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Conserved domains on  [gi|15242346|ref|NP_197065|]
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Proteasome component (PCI) domain protein [Arabidopsis thaliana]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PCI pfam01399
PCI domain; This domain has also been called the PINT motif (Proteasome, Int-6, Nip-1 and ...
 258-359 2.46e-13

PCI domain; This domain has also been called the PINT motif (Proteasome, Int-6, Nip-1 and TRIP-15).


:

Pssm-ID: 460195  Cd Length: 105  Bit Score: 65.70  E-value: 2.46e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242346   258 PVYQLLKIFLTQRLDAYMEFQNANSG-FLQTYGLVE--EDCVAKMRLLSLVDLASDDSgKIPYASIKNTLQVNDEEVELW 334
Cdd:pfam01399   2 AYRDLLRAFYSGDLSEFEEILADYKEeLLLDDGLAEhlEDLRRKIREHNLRQLSKPYS-SISLSDLAKLLGLSVDEVEKI 80

                          90       100
                  ....*....|....*....|....*
gi 15242346   335 VVKAITAKLVACKMDQMNQVVIVRQ 359
Cdd:pfam01399  81 LAKLIRDGRIRAKIDQVNGIVVFSK 105
eIF3m_C_helix pfam18005
eIF3 subunit M, C-terminal helix; This is the C-terminal helix domain found in Eukaryotic ...
 392-420 5.05e-10

eIF3 subunit M, C-terminal helix; This is the C-terminal helix domain found in Eukaryotic translation initiation factor 3 subunit M (eIF3m). In mammalian eIF3a, the C-terminal helix following the PCI domain is involved in interactions with other core subunits.


:

Pssm-ID: 465614  Cd Length: 29  Bit Score: 54.02  E-value: 5.05e-10
                          10        20
                  ....*....|....*....|....*....
gi 15242346   392 REFGQKQWQSLRTKLAAWRDNVRNVISTI 420
Cdd:pfam18005   1 RVFGKEQWQELRSRLDAWKSNLANVLEVI 29
 
Name Accession Description Interval E-value
PCI pfam01399
PCI domain; This domain has also been called the PINT motif (Proteasome, Int-6, Nip-1 and ...
 258-359 2.46e-13

PCI domain; This domain has also been called the PINT motif (Proteasome, Int-6, Nip-1 and TRIP-15).


Pssm-ID: 460195  Cd Length: 105  Bit Score: 65.70  E-value: 2.46e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242346   258 PVYQLLKIFLTQRLDAYMEFQNANSG-FLQTYGLVE--EDCVAKMRLLSLVDLASDDSgKIPYASIKNTLQVNDEEVELW 334
Cdd:pfam01399   2 AYRDLLRAFYSGDLSEFEEILADYKEeLLLDDGLAEhlEDLRRKIREHNLRQLSKPYS-SISLSDLAKLLGLSVDEVEKI 80

                          90       100
                  ....*....|....*....|....*
gi 15242346   335 VVKAITAKLVACKMDQMNQVVIVRQ 359
Cdd:pfam01399  81 LAKLIRDGRIRAKIDQVNGIVVFSK 105
eIF3m_C_helix pfam18005
eIF3 subunit M, C-terminal helix; This is the C-terminal helix domain found in Eukaryotic ...
 392-420 5.05e-10

eIF3 subunit M, C-terminal helix; This is the C-terminal helix domain found in Eukaryotic translation initiation factor 3 subunit M (eIF3m). In mammalian eIF3a, the C-terminal helix following the PCI domain is involved in interactions with other core subunits.


Pssm-ID: 465614  Cd Length: 29  Bit Score: 54.02  E-value: 5.05e-10
                          10        20
                  ....*....|....*....|....*....
gi 15242346   392 REFGQKQWQSLRTKLAAWRDNVRNVISTI 420
Cdd:pfam18005   1 RVFGKEQWQELRSRLDAWKSNLANVLEVI 29
PINT smart00088
motif in proteasome subunits, Int-6, Nip-1 and TRIP-15; Also called the PCI (Proteasome, COP9, ...
 292-362 1.01e-06

motif in proteasome subunits, Int-6, Nip-1 and TRIP-15; Also called the PCI (Proteasome, COP9, Initiation factor 3) domain. Unknown function.


Pssm-ID: 214509 [Multi-domain]  Cd Length: 88  Bit Score: 46.47  E-value: 1.01e-06
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15242346    292 EEDCVAKMRLLSLVDLASDDSgKIPYASIKNTLQVNDEEVELWVVKAITAKLVACKMDQMNQVVIVRQVSN 362
Cdd:smart00088   3 VERLQRKIRLTNLLQLSEPYS-SISLSDLAKLLGLSVPEVEKLVSKAIRDGEISAKIDQVNGIVEFEEVDP 72
 
Name Accession Description Interval E-value
PCI pfam01399
PCI domain; This domain has also been called the PINT motif (Proteasome, Int-6, Nip-1 and ...
 258-359 2.46e-13

PCI domain; This domain has also been called the PINT motif (Proteasome, Int-6, Nip-1 and TRIP-15).


Pssm-ID: 460195  Cd Length: 105  Bit Score: 65.70  E-value: 2.46e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242346   258 PVYQLLKIFLTQRLDAYMEFQNANSG-FLQTYGLVE--EDCVAKMRLLSLVDLASDDSgKIPYASIKNTLQVNDEEVELW 334
Cdd:pfam01399   2 AYRDLLRAFYSGDLSEFEEILADYKEeLLLDDGLAEhlEDLRRKIREHNLRQLSKPYS-SISLSDLAKLLGLSVDEVEKI 80

                          90       100
                  ....*....|....*....|....*
gi 15242346   335 VVKAITAKLVACKMDQMNQVVIVRQ 359
Cdd:pfam01399  81 LAKLIRDGRIRAKIDQVNGIVVFSK 105
eIF3m_C_helix pfam18005
eIF3 subunit M, C-terminal helix; This is the C-terminal helix domain found in Eukaryotic ...
 392-420 5.05e-10

eIF3 subunit M, C-terminal helix; This is the C-terminal helix domain found in Eukaryotic translation initiation factor 3 subunit M (eIF3m). In mammalian eIF3a, the C-terminal helix following the PCI domain is involved in interactions with other core subunits.


Pssm-ID: 465614  Cd Length: 29  Bit Score: 54.02  E-value: 5.05e-10
                          10        20
                  ....*....|....*....|....*....
gi 15242346   392 REFGQKQWQSLRTKLAAWRDNVRNVISTI 420
Cdd:pfam18005   1 RVFGKEQWQELRSRLDAWKSNLANVLEVI 29
PINT smart00088
motif in proteasome subunits, Int-6, Nip-1 and TRIP-15; Also called the PCI (Proteasome, COP9, ...
 292-362 1.01e-06

motif in proteasome subunits, Int-6, Nip-1 and TRIP-15; Also called the PCI (Proteasome, COP9, Initiation factor 3) domain. Unknown function.


Pssm-ID: 214509 [Multi-domain]  Cd Length: 88  Bit Score: 46.47  E-value: 1.01e-06
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15242346    292 EEDCVAKMRLLSLVDLASDDSgKIPYASIKNTLQVNDEEVELWVVKAITAKLVACKMDQMNQVVIVRQVSN 362
Cdd:smart00088   3 VERLQRKIRLTNLLQLSEPYS-SISLSDLAKLLGLSVPEVEKLVSKAIRDGEISAKIDQVNGIVEFEEVDP 72
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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