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Conserved domains on  [gi|15242147|ref|NP_197605|]
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Glyceraldehyde-3-phosphate dehydrogenase-like family protein [Arabidopsis thaliana]

Protein Classification

PLN02700 family protein( domain architecture ID 11477068)

PLN02700 family protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PLN02700 PLN02700
homoserine dehydrogenase family protein
1-376 0e+00

homoserine dehydrogenase family protein


:

Pssm-ID: 215377 [Multi-domain]  Cd Length: 377  Bit Score: 691.13  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147    1 MKKIPVLLMGCGGVGRHLLQHIVSCRSLHAKMGVHIRVIGVCDSKSLVAPMDVLKEELNDELLSEVCLIKSTGSALSKLG 80
Cdd:PLN02700   1 MKKIPVLLLGCGGVGRHLLRHIVSCRSLHAKQGVRIRVVGVCDSKSLVLAEDVLNEELDDALLSEVCLAKSKGSPLSALG 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147   81 AL-GGYRVVHDSELSTETEEIAKLLGKSTGLAVVDCSASMETIEILMKAVDLGCCIVLANKKPVTSTLEHYDKLALHPRF 159
Cdd:PLN02700  81 ALaGGCQVFNNSELSRKVIDIATLLGKSTGLVVVDCSASMETIGALNEAVDLGCCIVLANKKPLTSTLEDYDKLAAHPRR 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147  160 IRHESTVGAGLPVIASLNRIISSGDPVHRIVGSLSGTLGYVMSELEDGKPLSQVVQAAKKLGYTEPDPRDDLGGMDVARK 239
Cdd:PLN02700 161 IRHESTVGAGLPVIASLNRILSSGDPVHRIVGSLSGTLGYVMSELEDGKPFSEVVKQAKSLGYTEPDPRDDLGGMDVARK 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147  240 GLILARLLGKRIIMDSIKIESLYPEEMGPGLMSVDDFLHNGIVKLDQNIEERVKKASSKGCVLRYVCVIEGSSVQVGIRE 319
Cdd:PLN02700 241 ALILARLLGKRINMDSIKVESLYPEEMGPDLMSTDDFLHSGLVELDLPIEERVKEASLKGCVLRYVCVIEGSSCQVGIRE 320
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 15242147  320 VSKDSPLGRLRGSDNIVEIYSRCYKEQPLVIQGAGAGNDTTAAGVLADIIDLQDLFH 376
Cdd:PLN02700 321 LPKDSALGRLRGSDNVVEIYSRCYSEQPLVIQGAGAGNDTTAAGVLADILDLQDLFH 377
 
Name Accession Description Interval E-value
PLN02700 PLN02700
homoserine dehydrogenase family protein
1-376 0e+00

homoserine dehydrogenase family protein


Pssm-ID: 215377 [Multi-domain]  Cd Length: 377  Bit Score: 691.13  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147    1 MKKIPVLLMGCGGVGRHLLQHIVSCRSLHAKMGVHIRVIGVCDSKSLVAPMDVLKEELNDELLSEVCLIKSTGSALSKLG 80
Cdd:PLN02700   1 MKKIPVLLLGCGGVGRHLLRHIVSCRSLHAKQGVRIRVVGVCDSKSLVLAEDVLNEELDDALLSEVCLAKSKGSPLSALG 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147   81 AL-GGYRVVHDSELSTETEEIAKLLGKSTGLAVVDCSASMETIEILMKAVDLGCCIVLANKKPVTSTLEHYDKLALHPRF 159
Cdd:PLN02700  81 ALaGGCQVFNNSELSRKVIDIATLLGKSTGLVVVDCSASMETIGALNEAVDLGCCIVLANKKPLTSTLEDYDKLAAHPRR 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147  160 IRHESTVGAGLPVIASLNRIISSGDPVHRIVGSLSGTLGYVMSELEDGKPLSQVVQAAKKLGYTEPDPRDDLGGMDVARK 239
Cdd:PLN02700 161 IRHESTVGAGLPVIASLNRILSSGDPVHRIVGSLSGTLGYVMSELEDGKPFSEVVKQAKSLGYTEPDPRDDLGGMDVARK 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147  240 GLILARLLGKRIIMDSIKIESLYPEEMGPGLMSVDDFLHNGIVKLDQNIEERVKKASSKGCVLRYVCVIEGSSVQVGIRE 319
Cdd:PLN02700 241 ALILARLLGKRINMDSIKVESLYPEEMGPDLMSTDDFLHSGLVELDLPIEERVKEASLKGCVLRYVCVIEGSSCQVGIRE 320
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 15242147  320 VSKDSPLGRLRGSDNIVEIYSRCYKEQPLVIQGAGAGNDTTAAGVLADIIDLQDLFH 376
Cdd:PLN02700 321 LPKDSALGRLRGSDNVVEIYSRCYSEQPLVIQGAGAGNDTTAAGVLADILDLQDLFH 377
ThrA COG0460
Homoserine dehydrogenase [Amino acid transport and metabolism]; Homoserine dehydrogenase is ...
28-371 2.30e-72

Homoserine dehydrogenase [Amino acid transport and metabolism]; Homoserine dehydrogenase is part of the Pathway/BioSystem: Methionine biosynthesis


Pssm-ID: 440228 [Multi-domain]  Cd Length: 302  Bit Score: 227.62  E-value: 2.30e-72
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147  28 LHAKMGVHIRVIGVCDSKslvaPMDVLKEELNDELLsevcliksTGSALSklgalggyrVVHDSELSTeteeiakllgks 107
Cdd:COG0460   7 LARRLGLDLRVVGVAVRD----GMKPRGIDLPRWLL--------TTDLEE---------LIKDPEIDV------------ 53
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147 108 tglaVVDCSASMETI-EILMKAVDLGCCIVLANKKPVTstlEHYDKLA----LHPRFIRHESTVGAGLPVIASLNRIISs 182
Cdd:COG0460  54 ----VVELTGGSEPArELYLAALEAGKHVVTANKALLA---EHGKELFelarKNGVDLLFEAAVGGGIPIIKTLRELLA- 125
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147 183 GDPVHRIVGSLSGTLGYVMSELED-GKPLSQVVQAAKKLGYTEPDPRDDLGGMDVARKGLILARLL-GKRIIMDSIKIEs 260
Cdd:COG0460 126 GDRITRIEGILNGTTNYILTKMEEeGLSFSEALKEAQELGYAEADPTADVEGIDAARKLAILARLAfGTPVELEDVYVE- 204
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147 261 lypeemgpglmsvddflhnGIVKLDQnieERVKKASSKGCVLRYVCVIE----GSSVQVGIREVSKDSPLGRLRGSDNIV 336
Cdd:COG0460 205 -------------------GITRITA---EDIAAAKELGYVIKLLAIAErtggGVEARVHPTLVPADHPLASVNGVDNAV 262
                       330       340       350
                ....*....|....*....|....*....|....*
gi 15242147 337 EIYSRCYKEqpLVIQGAGAGNDTTAAGVLADIIDL 371
Cdd:COG0460 263 LVETDAYGE--LMFYGPGAGAEPTASAVLADLLDI 295
Homoserine_dh pfam00742
Homoserine dehydrogenase;
171-368 1.68e-60

Homoserine dehydrogenase;


Pssm-ID: 459921 [Multi-domain]  Cd Length: 178  Bit Score: 192.97  E-value: 1.68e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147   171 PVIASLNRIISsGDPVHRIVGSLSGTLGYVMSEL-EDGKPLSQVVQAAKKLGYTEPDPRDDLGGMDVARKGLILARLL-G 248
Cdd:pfam00742   1 PIIRTLRLSLA-GDRITRIEGILNGTTNYILTRMeEEGLSFSEALKEAQELGYAEADPTDDVEGIDAARKLAILARLAfG 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147   249 KRIIMDSIKIEslypeemgpglmsvddflhnGIVKLDqniEERVKKASSKGCVLRYVCVIEGS----SVQVGIREVSKDS 324
Cdd:pfam00742  80 LDVELEDVEVE--------------------GITRLT---AEDIAYAKELGKVIKLVASAKRDdggvEARVGPTLVPKDH 136
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 15242147   325 PLGRLRGSDNIVEIYSRCYkeQPLVIQGAGAGNDTTAAGVLADI 368
Cdd:pfam00742 137 PLASVKGVDNAVVIETDRY--GELVFYGPGAGALPTASAVLADL 178
 
Name Accession Description Interval E-value
PLN02700 PLN02700
homoserine dehydrogenase family protein
1-376 0e+00

homoserine dehydrogenase family protein


Pssm-ID: 215377 [Multi-domain]  Cd Length: 377  Bit Score: 691.13  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147    1 MKKIPVLLMGCGGVGRHLLQHIVSCRSLHAKMGVHIRVIGVCDSKSLVAPMDVLKEELNDELLSEVCLIKSTGSALSKLG 80
Cdd:PLN02700   1 MKKIPVLLLGCGGVGRHLLRHIVSCRSLHAKQGVRIRVVGVCDSKSLVLAEDVLNEELDDALLSEVCLAKSKGSPLSALG 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147   81 AL-GGYRVVHDSELSTETEEIAKLLGKSTGLAVVDCSASMETIEILMKAVDLGCCIVLANKKPVTSTLEHYDKLALHPRF 159
Cdd:PLN02700  81 ALaGGCQVFNNSELSRKVIDIATLLGKSTGLVVVDCSASMETIGALNEAVDLGCCIVLANKKPLTSTLEDYDKLAAHPRR 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147  160 IRHESTVGAGLPVIASLNRIISSGDPVHRIVGSLSGTLGYVMSELEDGKPLSQVVQAAKKLGYTEPDPRDDLGGMDVARK 239
Cdd:PLN02700 161 IRHESTVGAGLPVIASLNRILSSGDPVHRIVGSLSGTLGYVMSELEDGKPFSEVVKQAKSLGYTEPDPRDDLGGMDVARK 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147  240 GLILARLLGKRIIMDSIKIESLYPEEMGPGLMSVDDFLHNGIVKLDQNIEERVKKASSKGCVLRYVCVIEGSSVQVGIRE 319
Cdd:PLN02700 241 ALILARLLGKRINMDSIKVESLYPEEMGPDLMSTDDFLHSGLVELDLPIEERVKEASLKGCVLRYVCVIEGSSCQVGIRE 320
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 15242147  320 VSKDSPLGRLRGSDNIVEIYSRCYKEQPLVIQGAGAGNDTTAAGVLADIIDLQDLFH 376
Cdd:PLN02700 321 LPKDSALGRLRGSDNVVEIYSRCYSEQPLVIQGAGAGNDTTAAGVLADILDLQDLFH 377
thrA PRK09436
bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional
2-369 3.88e-94

bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional


Pssm-ID: 181856 [Multi-domain]  Cd Length: 819  Bit Score: 298.61  E-value: 3.88e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147    2 KKIPVLLMGCGGVGRHLLQHIVSCRSLHAKMGVHIRVIGVCDSKSLVapmdvlkeeLNDELLSevclikstgsalsklga 81
Cdd:PRK09436 464 QVLDVFVIGVGGVGGALLEQIKRQQPWLKKKNIDLRVCGIANSRKML---------LDEHGID----------------- 517
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147   82 LGGYRvvhdSELSTETEE--IAKLLG--KSTGLA---VVDCSASMETIEI---LMKAvdlGCCIVLANKKPVTSTLEHYD 151
Cdd:PRK09436 518 LDNWR----EELAEAGEPfdLDRLIRlvKEYHLLnpvIVDCTSSQAVADQyadFLAA---GFHVVTPNKKANTSSYAYYH 590
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147  152 KL---ALHPR--FiRHESTVGAGLPVIASLNRIISSGDPVHRIVGSLSGTLGYVMSELEDGKPLSQVVQAAKKLGYTEPD 226
Cdd:PRK09436 591 QLreaARKSRrkF-LYETNVGAGLPVIETLQNLLNAGDELLKFEGILSGSLSFIFGKLDEGMSFSEATRLAKEKGYTEPD 669
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147  227 PRDDLGGMDVARKGLILARLLGKRIIMDSIKIESLYPEEMGpGLMSVDDFLHNgIVKLDQNIEERVKKASSKGCVLRYVC 306
Cdd:PRK09436 670 PRDDLSGMDVARKLLILAREAGYELELEDIEVESVLPEEFD-ASGSVDEFMAR-LPELDAEFAARVAKARAEGKVLRYVG 747
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15242147  307 VIEGSSVQVGIREVSKDSPLGRLRGSDNIVEIYSRCYKEQPLVIQGAGAGNDTTAAGVLADII 369
Cdd:PRK09436 748 QIEDGKCRVGIAEVDANHPLYKVKGGENALAFYTRYYQPIPLVLRGYGAGNEVTAAGVFADLL 810
ThrA COG0460
Homoserine dehydrogenase [Amino acid transport and metabolism]; Homoserine dehydrogenase is ...
28-371 2.30e-72

Homoserine dehydrogenase [Amino acid transport and metabolism]; Homoserine dehydrogenase is part of the Pathway/BioSystem: Methionine biosynthesis


Pssm-ID: 440228 [Multi-domain]  Cd Length: 302  Bit Score: 227.62  E-value: 2.30e-72
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147  28 LHAKMGVHIRVIGVCDSKslvaPMDVLKEELNDELLsevcliksTGSALSklgalggyrVVHDSELSTeteeiakllgks 107
Cdd:COG0460   7 LARRLGLDLRVVGVAVRD----GMKPRGIDLPRWLL--------TTDLEE---------LIKDPEIDV------------ 53
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147 108 tglaVVDCSASMETI-EILMKAVDLGCCIVLANKKPVTstlEHYDKLA----LHPRFIRHESTVGAGLPVIASLNRIISs 182
Cdd:COG0460  54 ----VVELTGGSEPArELYLAALEAGKHVVTANKALLA---EHGKELFelarKNGVDLLFEAAVGGGIPIIKTLRELLA- 125
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147 183 GDPVHRIVGSLSGTLGYVMSELED-GKPLSQVVQAAKKLGYTEPDPRDDLGGMDVARKGLILARLL-GKRIIMDSIKIEs 260
Cdd:COG0460 126 GDRITRIEGILNGTTNYILTKMEEeGLSFSEALKEAQELGYAEADPTADVEGIDAARKLAILARLAfGTPVELEDVYVE- 204
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147 261 lypeemgpglmsvddflhnGIVKLDQnieERVKKASSKGCVLRYVCVIE----GSSVQVGIREVSKDSPLGRLRGSDNIV 336
Cdd:COG0460 205 -------------------GITRITA---EDIAAAKELGYVIKLLAIAErtggGVEARVHPTLVPADHPLASVNGVDNAV 262
                       330       340       350
                ....*....|....*....|....*....|....*
gi 15242147 337 EIYSRCYKEqpLVIQGAGAGNDTTAAGVLADIIDL 371
Cdd:COG0460 263 LVETDAYGE--LMFYGPGAGAEPTASAVLADLLDI 295
metL PRK09466
bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional
2-374 1.46e-63

bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional


Pssm-ID: 236530 [Multi-domain]  Cd Length: 810  Bit Score: 216.71  E-value: 1.46e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147    2 KKIPVLLMGCGGVGRHLLQHIVSCR-SLHAKMGVHIRVIGVCDS-KSLVAP--MDVL--KEELNDEllsevCLIKSTGSA 75
Cdd:PRK09466 457 KRIGLVLFGKGNIGSRWLELFAREQsTLSARTGFEFVLVGVVDSrRSLLNYdgLDASraLAFFDDE-----AVEWDEESL 531
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147   76 LSKLGALGgyrvvHDSelsteteeiakllgkstgLAVVDCSASMETIEILMKAVDLGCCIVLANKKPVTSTLEHY----D 151
Cdd:PRK09466 532 FLWLRAHP-----YDE------------------LVVLDVTASEQLALQYPDFASHGFHVISANKLAGSSPSNFYrqikD 588
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147  152 KLALHPRFIRHESTVGAGLPVIASLNRIISSGDPVHRIVGSLSGTLGYVMSELEDGKPLSQVVQAAKKLGYTEPDPRDDL 231
Cdd:PRK09466 589 AFAKTGRHWLYNATVGAGLPINHTVRDLRNSGDSILAISGIFSGTLSWLFLQFDGSVPFSELVDQAWQQGLTEPDPRDDL 668
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147  232 GGMDVARKGLILARLLGKRIIMDSIKIESLYPEEMGPGlmSVDDFLHNGiVKLDQNIEERVKKASSKGCVLRYVCVIEGS 311
Cdd:PRK09466 669 SGRDVMRKLVILAREAGYEIEPDDVRVESLVPAHLEDG--SLDQFFENG-DELDEQMLQRLEAAAEQGKVLRYVARFDAN 745
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15242147  312 -SVQVGIREVSKDSPLGRLRGSDNIVEIYSRCYKEQPLVIQGAGAGNDTTAAGVLADIIDL-QDL 374
Cdd:PRK09466 746 gKARVGVEAVRPDHPLANLLPCDNVFAIESRWYRDNPLVIRGPGAGREVTAGAIQSDLNRLaQLL 810
Homoserine_dh pfam00742
Homoserine dehydrogenase;
171-368 1.68e-60

Homoserine dehydrogenase;


Pssm-ID: 459921 [Multi-domain]  Cd Length: 178  Bit Score: 192.97  E-value: 1.68e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147   171 PVIASLNRIISsGDPVHRIVGSLSGTLGYVMSEL-EDGKPLSQVVQAAKKLGYTEPDPRDDLGGMDVARKGLILARLL-G 248
Cdd:pfam00742   1 PIIRTLRLSLA-GDRITRIEGILNGTTNYILTRMeEEGLSFSEALKEAQELGYAEADPTDDVEGIDAARKLAILARLAfG 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147   249 KRIIMDSIKIEslypeemgpglmsvddflhnGIVKLDqniEERVKKASSKGCVLRYVCVIEGS----SVQVGIREVSKDS 324
Cdd:pfam00742  80 LDVELEDVEVE--------------------GITRLT---AEDIAYAKELGKVIKLVASAKRDdggvEARVGPTLVPKDH 136
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 15242147   325 PLGRLRGSDNIVEIYSRCYkeQPLVIQGAGAGNDTTAAGVLADI 368
Cdd:pfam00742 137 PLASVKGVDNAVVIETDRY--GELVFYGPGAGALPTASAVLADL 178
PRK08374 PRK08374
homoserine dehydrogenase; Provisional
2-369 1.73e-29

homoserine dehydrogenase; Provisional


Pssm-ID: 169409 [Multi-domain]  Cd Length: 336  Bit Score: 116.44  E-value: 1.73e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147    2 KKIPVLLMGCGGVGRHLLQHIVS-CRSLHAKMGVHIRVIGVCDSKSLVApmdvLKEELNdelLSEVCLIK-STGsalsKL 79
Cdd:PRK08374   1 MEVKVSIFGFGNVGRAVAEVLAEkSRVFKERYGVELKVVSITDTSGTIW----LPEDID---LREAKEVKeNFG----KL 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147   80 GALGGYRVVHDSELSTETEEIAKLLgkstglaVVDCSASMETIEILMKAVDLGCCIVLANKKPVTstlEHYDKLALHPRF 159
Cdd:PRK08374  70 SNWGNDYEVYNFSPEEIVEEIDADI-------VVDVTNDKNAHEWHLEALKEGKSVVTSNKPPIA---FHYDELLDLANE 139
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147  160 ----IRHESTVGAGLPVIASLNRIISsGDPVHRIVGSLSGTLGYVMSELEDGKPLSQVVQAAKKLGYTEPDPRDDLGGMD 235
Cdd:PRK08374 140 rnlpYLFEATVMAGTPIIGLLRENLL-GDTVKRIEAVVNATTTFILTRMEQGKTFEEALKEAQTLGIAERDPSKDIDGID 218
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147  236 VARKGLILARLlgkriimdsikieSLYPEEmgpglmsvddFLHNGIVKLDQNIEERVKKASSKGCVLRYVCVIEGSSVQV 315
Cdd:PRK08374 219 AGYKATILHWV-------------AFPPIT----------FEEVGIRGIKDVTEGEIERAKAKGRNVRLVATVEEGRISV 275
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....
gi 15242147  316 GIREVSKDSPLGrLRGSDNIVEIYSRCYKEqpLVIQGAGAGNDTTAAGVLADII 369
Cdd:PRK08374 276 KPKKLPENSPLA-VEGVENAAVIKTDLLGE--LVLKGPGAGGKETASGVVTDII 326
PRK06270 PRK06270
homoserine dehydrogenase; Provisional
2-373 1.14e-25

homoserine dehydrogenase; Provisional


Pssm-ID: 235763 [Multi-domain]  Cd Length: 341  Bit Score: 105.72  E-value: 1.14e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147    2 KKIPVLLMGCGGVGRHLLQHIVS-CRSLHAKMGVHIRVIGVCDSK-SLVAPmdvlkEELNDELLSEVclIKSTGsalsKL 79
Cdd:PRK06270   1 MEMKIALIGFGGVGQGVAELLAEkREYLKKRYGLDLKVVAIADSSgSAIDP-----DGLDLELALKV--KEETG----KL 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147   80 GALGGYRVVHDSELSTETEEiAKLLGKSTGLAVVDCSASMETIeilMKAVDLGCCIVLANKKPVTStleHYDKLAL---- 155
Cdd:PRK06270  70 ADYPEGGGEISGLEVIRSVD-ADVVVEATPTNIETGEPALSHC---RKALERGKHVVTSNKGPLAL---AYKELKElakk 142
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147  156 HPRFIRHESTVGAGLPVIASLNRIISSGDpVHRIVGSLSGTLGYVMSEL-EDGKPLSQVVQAAKKLGYTEPDPRDDLGGM 234
Cdd:PRK06270 143 NGVRFRYEATVGGAMPIINLAKETLAGND-IKSIKGILNGTTNYILTRMeEEGLSYEQALAEAQELGYAEADPTYDVEGI 221
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147  235 DVARKGLILAR-LLGKRIIMDSIKIEslypeemgpglmsvddflhnGIVKLDqniEERVKKASSKGCVLRYVC-VIEGSS 312
Cdd:PRK06270 222 DAALKVVILANsILGADLTIKDVEVE--------------------GITKIT---PEAIELAAKEGYRIKLIGeVSREKD 278
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15242147  313 VQVGIREVSKDSPLgRLRGSDNIVEIysRCYKEQPLVIQGAGAGNDTTAAGVLADIIDLQD 373
Cdd:PRK06270 279 LSVSPRLVPLDHPL-AVSGTLNAATF--ETDLAGDVTVVGRGAGSIETASAILSDLIAIHD 336
PRK06392 PRK06392
homoserine dehydrogenase; Provisional
4-261 1.75e-17

homoserine dehydrogenase; Provisional


Pssm-ID: 102354 [Multi-domain]  Cd Length: 326  Bit Score: 82.23  E-value: 1.75e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147    4 IPVLLMGCGGVGRHLLQhIVSCRSLHAKMGVHIRVIGVCDSKSLVAPMDVLKeelndelLSEVCLIKSTGSAlsklgalg 83
Cdd:PRK06392   1 IRISIIGLGNVGLNVLR-IIKSRNDDRRNNNGISVVSVSDSKLSYYNERGLD-------IGKIISYKEKGRL-------- 64
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147   84 gyrvvhdSELSTETEEIAKLLGKSTGLaVVDCS-ASMETIE---ILMKAVDLGCCIVLANKKPVTSTL-EHYDKLALHPR 158
Cdd:PRK06392  65 -------EEIDYEKIKFDEIFEIKPDV-IVDVTpASKDGIReknLYINAFEHGIDVVTANKSGLANHWhDIMDSASKNRR 136
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147  159 FIRHESTVGAGLPVIASLNRIISSGDpVHRIVGSLSGTLGYVMSELEDGKPLSQVVQAAKKLGYTEPDPRDDLGGMDVAR 238
Cdd:PRK06392 137 IIRYEATVAGGVPLFSLRDYSTLPSR-IKNFRGIVSSTINYVIRQEANGRGFLDVVKIAQKMGIAETNYSDDLMGLDAAR 215
                        250       260
                 ....*....|....*....|....
gi 15242147  239 KGLILA-RLLGKRIIMDSIKIESL 261
Cdd:PRK06392 216 KSVILAnHLFGKDYTLRDVTYDGI 239
PRK06349 PRK06349
homoserine dehydrogenase; Provisional
123-371 5.04e-16

homoserine dehydrogenase; Provisional


Pssm-ID: 235783 [Multi-domain]  Cd Length: 426  Bit Score: 78.96  E-value: 5.04e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147  123 EILMKAVDLGCCIVLANKkpvtstlehyDKLALH-----------PRFIRHESTVGAGLPVIASLNRiiS-SGDPVHRIV 190
Cdd:PRK06349  88 ELILKALEAGKHVVTANK----------ALLAVHgaelfaaaeekGVDLYFEAAVAGGIPIIKALRE--GlAANRITRVM 155
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147  191 GSLSGTLGYVMSELED-GKPLSQVVQAAKKLGYTEPDPRDDLGGMDVARKGLILARL-LGKRIIMDSIKIEslypeemgp 268
Cdd:PRK06349 156 GIVNGTTNYILTKMTEeGLSFEDALKEAQRLGYAEADPTFDVEGIDAAHKLAILASLaFGTRVDFDDVYVE--------- 226
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147  269 glmsvddflhnGIVKLDQnieERVKKASSKGCVLRYVCVIEGSSVQVGIRE----VSKDSPLGRLRGSDNIVEIYSRCYK 344
Cdd:PRK06349 227 -----------GISKITA---EDIAYAKELGYRIKLLGIAERTEEGIELRVhptlIPKSHPLANVNGVMNAVFVEGDAVG 292
                        250       260
                 ....*....|....*....|....*..
gi 15242147  345 EqpLVIQGAGAGNDTTAAGVLADIIDL 371
Cdd:PRK06349 293 E--TMFYGPGAGGLPTASAVVADLVDI 317
PRK06813 PRK06813
homoserine dehydrogenase; Validated
3-371 2.09e-07

homoserine dehydrogenase; Validated


Pssm-ID: 168683 [Multi-domain]  Cd Length: 346  Bit Score: 52.17  E-value: 2.09e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147    3 KIPVLLMGCGGVGRHLLQHIVSCRSLHAKM-GVHIRVIGVCDSKSLVapmdvlkeeLNDELLS-EVCLIKSTGSAlsklg 80
Cdd:PRK06813   2 KIKVVLSGYGTVGREFIKLLNEKYLYINETyGIDLVVSGVLGRNVAI---------HNEDGLSiHHLLRYGGGSC----- 67
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147   81 ALGGYRVVHDSELSTETEEiAKLLGKSTGLAVVDCSASMETIEilmKAVDLGCCIVLANKKPVTSTLEHYDKLALHPRF- 159
Cdd:PRK06813  68 AIEKYIEHHPEERATDNIS-GTVLVESTVTNLKDGNPGKQYIK---QAIEKKMDIVAISKGALVTNWREINEAAKIANVr 143
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147  160 IRHESTVGAGLPVIaSLNRIISSGDPVHRIVGSLSGTLGYVMSEL-EDGKPLSQVVQAAKKLGYTEPDPRDDLGGMDVAR 238
Cdd:PRK06813 144 IRYSGATAAALPTL-DIGQFSLAGCHIEKIEGILNGTTNYILTKMnEEDITFEEALKEAQSKGIAETNPILDVSGSDSAC 222
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147  239 KGLILA-RLLGKRIIMDSIKIeslypeemgpglmsvddflhNGIVKLDQnieERVKKASSKGCVLRYVCVI----EGS-S 312
Cdd:PRK06813 223 KLLLLTnSLMGTENKLTDIHI--------------------KGIEHVTK---QQIRNAKEQNKIIKLIASAykdnEGNvN 279
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242147  313 VQVGIREVSKDSPLGRLRGSDNIVEIysrCYKEQPLVIQGAGAGNDT-TAAGVLADIIDL 371
Cdd:PRK06813 280 LNVEPYKIEKNHPLANVNGTEKGITF---FTDTMGQVTTIGGASNPRgAAAAALKDIINL 336
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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