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Conserved domains on  [gi|334188205|ref|NP_199331|]
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Flavin-binding monooxygenase family protein [Arabidopsis thaliana]

Protein Classification

flavin-containing monooxygenase( domain architecture ID 11449697)

flavin-containing monooxygenase (FMO) catalyses the flavin-dependent oxidation of ketones and cyclic ketones to esters and lactones, by using molecular oxygen and NAD(P)H.

CATH:  3.50.50.60
Gene Ontology:  GO:0016709|GO:0004497|GO:0050660
PubMed:  20015679|33588053

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 12-406 3.01e-75

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


:

Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 241.69  E-value: 3.01e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205  12 RVAIIGAGVSGLAAAKHLARHHP--QVFEASDSIGGVWRKCTYETTKLQSVRVSYELSDFLWPnRGESSFPTYVDVLDYL 89
Cdd:COG2072    8 DVVVIGAGQAGLAAAYHLRRAGIdfVVLEKADDVGGTWRDNRYPGLRLDTPSHLYSLPFFPNW-SDDPDFPTGDEILAYL 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205  90 EAYAKHFNLVKFIKFNSKVVELRFIGDGktlqmgdlgaygnllpgkPVWEVAVNTGDgdiQWHAfEYVVVCAGkYGDVPR 169
Cdd:COG2072   87 EAYADKFGLRRPIRFGTEVTSARWDEAD------------------GRWTVTTDDGE---TLTA-RFVVVATG-PLSRPK 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205 170 TPTFPvkkGPEIFKGKVLHSMDYsklqkeKASQLLHGKKVAVIGFKKSAIDLALESAlanqgKEGKTCTMVVRTPHWVIP 249
Cdd:COG2072  144 IPDIP---GLEDFAGEQLHSADW------RNPVDLAGKRVLVVGTGASAVQIAPELA-----RVAAHVTVFQRTPPWVLP 209

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205 250 ------------HYW---------RATVSKFIESYVLWKLPLEKYG-LKPDHAFeedyaSCQMALVPEKFFEEADKGMI- 306
Cdd:COG2072  210 rpnydpergrpaNYLgleappalnRRDARAWLRRLLRAQVKDPELGlLTPDYPP-----GCKRPLLSTDYYEALRRGNVe 284

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205 307 ----RFKRTTnwwfyDEGIEFEDGTTLEADVVILATGYDgmkklkaivpePFRSWLEFP-------WGIMPLYRGTIHPL 375
Cdd:COG2072  285 lvtgGIERIT-----EDGVVFADGTEHEVDVIVWATGFR-----------ADLPWLAPLdvrgrdgRSGPRAYLGVVVPG 348

                        410       420       430
                 ....*....|....*....|....*....|....*.
gi 334188205 376 IPNMGFIGYVQSSSNlkSS-----ELHSRWLSQLLD 406
Cdd:COG2072  349 FPNLFFLGPNSPSGH--SSltlgaERQARYIARLIA 382
 
Name Accession Description Interval E-value
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 12-406 3.01e-75

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 241.69  E-value: 3.01e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205  12 RVAIIGAGVSGLAAAKHLARHHP--QVFEASDSIGGVWRKCTYETTKLQSVRVSYELSDFLWPnRGESSFPTYVDVLDYL 89
Cdd:COG2072    8 DVVVIGAGQAGLAAAYHLRRAGIdfVVLEKADDVGGTWRDNRYPGLRLDTPSHLYSLPFFPNW-SDDPDFPTGDEILAYL 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205  90 EAYAKHFNLVKFIKFNSKVVELRFIGDGktlqmgdlgaygnllpgkPVWEVAVNTGDgdiQWHAfEYVVVCAGkYGDVPR 169
Cdd:COG2072   87 EAYADKFGLRRPIRFGTEVTSARWDEAD------------------GRWTVTTDDGE---TLTA-RFVVVATG-PLSRPK 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205 170 TPTFPvkkGPEIFKGKVLHSMDYsklqkeKASQLLHGKKVAVIGFKKSAIDLALESAlanqgKEGKTCTMVVRTPHWVIP 249
Cdd:COG2072  144 IPDIP---GLEDFAGEQLHSADW------RNPVDLAGKRVLVVGTGASAVQIAPELA-----RVAAHVTVFQRTPPWVLP 209

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205 250 ------------HYW---------RATVSKFIESYVLWKLPLEKYG-LKPDHAFeedyaSCQMALVPEKFFEEADKGMI- 306
Cdd:COG2072  210 rpnydpergrpaNYLgleappalnRRDARAWLRRLLRAQVKDPELGlLTPDYPP-----GCKRPLLSTDYYEALRRGNVe 284

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205 307 ----RFKRTTnwwfyDEGIEFEDGTTLEADVVILATGYDgmkklkaivpePFRSWLEFP-------WGIMPLYRGTIHPL 375
Cdd:COG2072  285 lvtgGIERIT-----EDGVVFADGTEHEVDVIVWATGFR-----------ADLPWLAPLdvrgrdgRSGPRAYLGVVVPG 348

                        410       420       430
                 ....*....|....*....|....*....|....*.
gi 334188205 376 IPNMGFIGYVQSSSNlkSS-----ELHSRWLSQLLD 406
Cdd:COG2072  349 FPNLFFLGPNSPSGH--SSltlgaERQARYIARLIA 382
FMO-like pfam00743
Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone ...
 12-459 1.52e-40

Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone mono-oxygenase and a number of different mono-oxygenases.


Pssm-ID: 395602 [Multi-domain]  Cd Length: 531  Bit Score: 152.24  E-value: 1.52e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205   12 RVAIIGAGVSGLAAAKHLARH--HPQVFEASDSIGGVWRKCTY----ETTKLQSV--RVSYEL---SDFLWPNrgesSFP 80
Cdd:pfam00743   3 KVAVIGAGVSGLASIKCCLEEglEPTCFERSDDIGGLWRFTENveegRASIYKSVitNTSKEMscfSDFPFPE----DYP 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205   81 TYVD---VLDYLEAYAKHFNLVKFIKFNSKVVELRfigdgktlQMGDLGAYGNllpgkpvWEVaVNTGDGDIQWHAFEYV 157
Cdd:pfam00743  79 NFMHnskFLEYFRMFAKEFDLLKYIQFKTTVCSVK--------KRPDFSTSGQ-------WEV-VTEHEGKQESAVFDAV 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205  158 VVCAGKYGDvPRTP--TFPvkkGPEIFKGKVLHSMDYsklqkeKASQLLHGKKVAVIGFKKSAIDLALE-SALANQgkeg 234
Cdd:pfam00743 143 MVCTGHHTN-PHLPleSFP---GIEKFKGQYFHSRDY------KHPEGFTGKRVLVIGIGNSGGDIAVElSHTAAQ---- 208

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205  235 ktCTMVVRTPHWVIPHYW-----------------------RATVSKFIESYVLWKLPLEKYGLKPDH-------AFEED 284
Cdd:pfam00743 209 --VFLSTRRGSWVLSRVSdhgypwdmlfstrftsflrnilpTSISNWLMEKQMNRRFNHENYGLKPKNralskepVVNDD 286

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205  285 YASCQMAlvpekffeeadkGMIRFKRTTNwWFYDEGIEFEDGTTLEA-DVVILATGYDgmkklkaiVPEPF--RSWLEFP 361
Cdd:pfam00743 287 LPNRILC------------GAVKVKPNVK-EFTETSAIFEDGTVEEDiDVVIFATGYT--------FAFPFleESLVKVE 345

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205  362 WGIMPLYRGTIHPLI--PNMGFIGYVQS-SSNLKSSELHSRWLSQLLDGKFTLPSKEKMLDQFLKEMHVMRRSSRFFKNH 438
Cdd:pfam00743 346 NNKVSLYKYVFPPNLekPTLAIIGLIQPlGSIIPTVELQARWATRVFKGLCTLPSQSEMMAEINKRQEKKIKRFGDSQSH 425

                         490       500
                  ....*....|....*....|.
gi 334188205  439 CFSTFSIQHADDLSKDMNLKP 459
Cdd:pfam00743 426 TIQTDYIDYMDELALFIGAKP 446
PLN02172 PLN02172
flavin-containing monooxygenase FMO GS-OX
 1-419 4.25e-21

flavin-containing monooxygenase FMO GS-OX


Pssm-ID: 215116 [Multi-domain]  Cd Length: 461  Bit Score: 95.31  E-value: 4.25e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205   1 MAYNYNMHTSSRVAIIGAGVSGLAAAKHLAR--HHPQVFEASDSIGGVW--------------------RKCTYETTKLQ 58
Cdd:PLN02172   1 MAPAQNPINSQHVAVIGAGAAGLVAARELRRegHTVVVFEREKQVGGLWvytpksesdplsldptrsivHSSVYESLRTN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205  59 SVRVSYELSDFLW------PNRGESSFPTYVDVLDYLEAYAKHFNLVKFIKFNSKVVELRFIgDGKtlqmgdlgaygnll 132
Cdd:PLN02172  81 LPRECMGYRDFPFvprfddESRDSRRYPSHREVLAYLQDFAREFKIEEMVRFETEVVRVEPV-DGK-------------- 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205 133 pgkpvWEVAVNTGDGDIQWHAFEYVVVCAGKYGDvPRTPTFPvkkGPEIFKGKVLHSMDYsklqkeKASQLLHGKKVAVI 212
Cdd:PLN02172 146 -----WRVQSKNSGGFSKDEIFDAVVVCNGHYTE-PNVAHIP---GIKSWPGKQIHSHNY------RVPDPFKNEVVVVI 210

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205 213 GFKKSAIDLAlesalanqgkegKTCTMVVRTPHwviphywraTVSKFIESYVLWKLPlekyglkpdhafeedyascqmal 292
Cdd:PLN02172 211 GNFASGADIS------------RDIAKVAKEVH---------IASRASESDTYEKLP----------------------- 246

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205 293 VPEkffeeadkgmirfkrtTNWWFYDE--------GIEFEDGTTLEADVVILATGYDgmkklkaivpepfrswLEFPW-- 362
Cdd:PLN02172 247 VPQ----------------NNLWMHSEidtahedgSIVFKNGKVVYADTIVHCTGYK----------------YHFPFle 294

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 334188205 363 --GIM--------PLYRGTIHP-LIPNMGFIGYVQSSSNLKSSELHSRWLSQLLDGKFTLPSKEKMLD 419
Cdd:PLN02172 295 tnGYMridenrvePLYKHVFPPaLAPGLSFIGLPAMGIQFVMFEIQSKWVAAVLSGRVTLPSEDKMME 362
proto_IX_ox TIGR00562
protoporphyrinogen oxidase; This enzyme oxidizes protoporphyrinogen IX to protoporphyrin IX, a ...
 13-45 1.18e-04

protoporphyrinogen oxidase; This enzyme oxidizes protoporphyrinogen IX to protoporphyrin IX, a precursor of heme and chlorophyll. Bacillus subtilis HemY also has coproporphyrinogen III to coproporphyrin III oxidase activity in a heterologous expression system, although the role for this activity in vivo is unclear. This protein is a flavoprotein and has a beta-alpha-beta dinucleotide binding motif near the amino end. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin]


Pssm-ID: 213540 [Multi-domain]  Cd Length: 462  Bit Score: 44.44  E-value: 1.18e-04
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 334188205   13 VAIIGAGVSGLAAAKHLARHHPQ------VFEASDSIGG 45
Cdd:TIGR00562   5 VVIIGGGISGLCAAYYLEKEIPElpveltLVEASDRVGG 43
 
Name Accession Description Interval E-value
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 12-406 3.01e-75

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 241.69  E-value: 3.01e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205  12 RVAIIGAGVSGLAAAKHLARHHP--QVFEASDSIGGVWRKCTYETTKLQSVRVSYELSDFLWPnRGESSFPTYVDVLDYL 89
Cdd:COG2072    8 DVVVIGAGQAGLAAAYHLRRAGIdfVVLEKADDVGGTWRDNRYPGLRLDTPSHLYSLPFFPNW-SDDPDFPTGDEILAYL 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205  90 EAYAKHFNLVKFIKFNSKVVELRFIGDGktlqmgdlgaygnllpgkPVWEVAVNTGDgdiQWHAfEYVVVCAGkYGDVPR 169
Cdd:COG2072   87 EAYADKFGLRRPIRFGTEVTSARWDEAD------------------GRWTVTTDDGE---TLTA-RFVVVATG-PLSRPK 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205 170 TPTFPvkkGPEIFKGKVLHSMDYsklqkeKASQLLHGKKVAVIGFKKSAIDLALESAlanqgKEGKTCTMVVRTPHWVIP 249
Cdd:COG2072  144 IPDIP---GLEDFAGEQLHSADW------RNPVDLAGKRVLVVGTGASAVQIAPELA-----RVAAHVTVFQRTPPWVLP 209

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205 250 ------------HYW---------RATVSKFIESYVLWKLPLEKYG-LKPDHAFeedyaSCQMALVPEKFFEEADKGMI- 306
Cdd:COG2072  210 rpnydpergrpaNYLgleappalnRRDARAWLRRLLRAQVKDPELGlLTPDYPP-----GCKRPLLSTDYYEALRRGNVe 284

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205 307 ----RFKRTTnwwfyDEGIEFEDGTTLEADVVILATGYDgmkklkaivpePFRSWLEFP-------WGIMPLYRGTIHPL 375
Cdd:COG2072  285 lvtgGIERIT-----EDGVVFADGTEHEVDVIVWATGFR-----------ADLPWLAPLdvrgrdgRSGPRAYLGVVVPG 348

                        410       420       430
                 ....*....|....*....|....*....|....*.
gi 334188205 376 IPNMGFIGYVQSSSNlkSS-----ELHSRWLSQLLD 406
Cdd:COG2072  349 FPNLFFLGPNSPSGH--SSltlgaERQARYIARLIA 382
FMO-like pfam00743
Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone ...
 12-459 1.52e-40

Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone mono-oxygenase and a number of different mono-oxygenases.


Pssm-ID: 395602 [Multi-domain]  Cd Length: 531  Bit Score: 152.24  E-value: 1.52e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205   12 RVAIIGAGVSGLAAAKHLARH--HPQVFEASDSIGGVWRKCTY----ETTKLQSV--RVSYEL---SDFLWPNrgesSFP 80
Cdd:pfam00743   3 KVAVIGAGVSGLASIKCCLEEglEPTCFERSDDIGGLWRFTENveegRASIYKSVitNTSKEMscfSDFPFPE----DYP 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205   81 TYVD---VLDYLEAYAKHFNLVKFIKFNSKVVELRfigdgktlQMGDLGAYGNllpgkpvWEVaVNTGDGDIQWHAFEYV 157
Cdd:pfam00743  79 NFMHnskFLEYFRMFAKEFDLLKYIQFKTTVCSVK--------KRPDFSTSGQ-------WEV-VTEHEGKQESAVFDAV 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205  158 VVCAGKYGDvPRTP--TFPvkkGPEIFKGKVLHSMDYsklqkeKASQLLHGKKVAVIGFKKSAIDLALE-SALANQgkeg 234
Cdd:pfam00743 143 MVCTGHHTN-PHLPleSFP---GIEKFKGQYFHSRDY------KHPEGFTGKRVLVIGIGNSGGDIAVElSHTAAQ---- 208

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205  235 ktCTMVVRTPHWVIPHYW-----------------------RATVSKFIESYVLWKLPLEKYGLKPDH-------AFEED 284
Cdd:pfam00743 209 --VFLSTRRGSWVLSRVSdhgypwdmlfstrftsflrnilpTSISNWLMEKQMNRRFNHENYGLKPKNralskepVVNDD 286

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205  285 YASCQMAlvpekffeeadkGMIRFKRTTNwWFYDEGIEFEDGTTLEA-DVVILATGYDgmkklkaiVPEPF--RSWLEFP 361
Cdd:pfam00743 287 LPNRILC------------GAVKVKPNVK-EFTETSAIFEDGTVEEDiDVVIFATGYT--------FAFPFleESLVKVE 345

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205  362 WGIMPLYRGTIHPLI--PNMGFIGYVQS-SSNLKSSELHSRWLSQLLDGKFTLPSKEKMLDQFLKEMHVMRRSSRFFKNH 438
Cdd:pfam00743 346 NNKVSLYKYVFPPNLekPTLAIIGLIQPlGSIIPTVELQARWATRVFKGLCTLPSQSEMMAEINKRQEKKIKRFGDSQSH 425

                         490       500
                  ....*....|....*....|.
gi 334188205  439 CFSTFSIQHADDLSKDMNLKP 459
Cdd:pfam00743 426 TIQTDYIDYMDELALFIGAKP 446
PLN02172 PLN02172
flavin-containing monooxygenase FMO GS-OX
 1-419 4.25e-21

flavin-containing monooxygenase FMO GS-OX


Pssm-ID: 215116 [Multi-domain]  Cd Length: 461  Bit Score: 95.31  E-value: 4.25e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205   1 MAYNYNMHTSSRVAIIGAGVSGLAAAKHLAR--HHPQVFEASDSIGGVW--------------------RKCTYETTKLQ 58
Cdd:PLN02172   1 MAPAQNPINSQHVAVIGAGAAGLVAARELRRegHTVVVFEREKQVGGLWvytpksesdplsldptrsivHSSVYESLRTN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205  59 SVRVSYELSDFLW------PNRGESSFPTYVDVLDYLEAYAKHFNLVKFIKFNSKVVELRFIgDGKtlqmgdlgaygnll 132
Cdd:PLN02172  81 LPRECMGYRDFPFvprfddESRDSRRYPSHREVLAYLQDFAREFKIEEMVRFETEVVRVEPV-DGK-------------- 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205 133 pgkpvWEVAVNTGDGDIQWHAFEYVVVCAGKYGDvPRTPTFPvkkGPEIFKGKVLHSMDYsklqkeKASQLLHGKKVAVI 212
Cdd:PLN02172 146 -----WRVQSKNSGGFSKDEIFDAVVVCNGHYTE-PNVAHIP---GIKSWPGKQIHSHNY------RVPDPFKNEVVVVI 210

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205 213 GFKKSAIDLAlesalanqgkegKTCTMVVRTPHwviphywraTVSKFIESYVLWKLPlekyglkpdhafeedyascqmal 292
Cdd:PLN02172 211 GNFASGADIS------------RDIAKVAKEVH---------IASRASESDTYEKLP----------------------- 246

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205 293 VPEkffeeadkgmirfkrtTNWWFYDE--------GIEFEDGTTLEADVVILATGYDgmkklkaivpepfrswLEFPW-- 362
Cdd:PLN02172 247 VPQ----------------NNLWMHSEidtahedgSIVFKNGKVVYADTIVHCTGYK----------------YHFPFle 294

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 334188205 363 --GIM--------PLYRGTIHP-LIPNMGFIGYVQSSSNLKSSELHSRWLSQLLDGKFTLPSKEKMLD 419
Cdd:PLN02172 295 tnGYMridenrvePLYKHVFPPaLAPGLSFIGLPAMGIQFVMFEIQSKWVAAVLSGRVTLPSEDKMME 362
Pyr_redox_3 pfam13738
Pyridine nucleotide-disulphide oxidoreductase;
79-342 2.18e-11

Pyridine nucleotide-disulphide oxidoreductase;


Pssm-ID: 404603 [Multi-domain]  Cd Length: 296  Bit Score: 64.55  E-value: 2.18e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205   79 FPTYVDVLDYLEAYAKHFNLVkfIKFNSKVVELRFIGDGKTlqmgdlgaygnllpgkpvwevaVNTGDGDIQWHafeYVV 158
Cdd:pfam13738  71 HPSGNEYAEYLRRVADHFELP--INLFEEVTSVKKEDDGFV----------------------VTTSKGTYQAR---YVI 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205  159 VCAGKYgDVPRTPTFPVKKgpeIFKGKVLHSMDYSklqkekasqllhGKKVAVIGFKKSAIDLALEsaLANQGKEgktCT 238
Cdd:pfam13738 124 IATGEF-DFPNKLGVPELP---KHYSYVKDFHPYA------------GQKVVVIGGYNSAVDAALE--LVRKGAR---VT 182

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205  239 MVVRTPHWVIPHywratvskfiesyvlwklPLEKYGLKPD--HAFEEDYASCQMALVPEKFFEEadkgmIRFKRTTnwwf 316
Cdd:pfam13738 183 VLYRGSEWEDRD------------------SDPSYSLSPDtlNRLEELVKNGKIKAHFNAEVKE-----ITEVDVS---- 235

                         250       260
                  ....*....|....*....|....*..
gi 334188205  317 YDegIEFEDGTTLEA-DVVILATGYDG 342
Cdd:pfam13738 236 YK--VHTEDGRKVTSnDDPILATGYHP 260
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 12-90 2.39e-09

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 59.08  E-value: 2.39e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205  12 RVAIIGAGVSGLAAAKHLAR--HHPQVFEASDSIGGvwrkctyettKLQSVRVsyelSDFLWPNRGESSFPTYVDVLDYL 89
Cdd:COG1232    3 RVAVIGGGIAGLTAAYRLAKagHEVTVLEASDRVGG----------LIRTVEV----DGFRIDRGPHSFLTRDPEVLELL 68


                 .
gi 334188205  90 E 90
Cdd:COG1232   69 R 69
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
12-47 3.70e-09

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 58.39  E-value: 3.70e-09
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 334188205  12 RVAIIGAGVSGLAAAKHLAR--HHPQVFEASDSIGG-VW 47
Cdd:COG1231    9 DVVIVGAGLAGLAAARELRKagLDVTVLEARDRVGGrVW 47
Ppro0129 COG2907
Predicted flavin-containing amine oxidase [General function prediction only];
9-45 4.54e-09

Predicted flavin-containing amine oxidase [General function prediction only];


Pssm-ID: 442151 [Multi-domain]  Cd Length: 423  Bit Score: 58.20  E-value: 4.54e-09
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 334188205   9 TSSRVAIIGAGVSGLAAAKHLARHHP-QVFEASDSIGG 45
Cdd:COG2907    2 ARMRIAVIGSGISGLTAAWLLSRRHDvTLFEANDRLGG 39
YdhS COG4529
Uncharacterized NAD(P)/FAD-binding protein YdhS [General function prediction only];
7-235 5.82e-09

Uncharacterized NAD(P)/FAD-binding protein YdhS [General function prediction only];


Pssm-ID: 443597 [Multi-domain]  Cd Length: 466  Bit Score: 58.04  E-value: 5.82e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205   7 MHTSS-RVAIIGAGVSGLAAAKHLARHHPQ-----VFEASDSIG-GVwrkcTYETT------KLQSVRVSY---ELSDFL 70
Cdd:COG4529    1 MTGARkRIAIIGGGASGTALAIHLLRRAPEplritLFEPRPELGrGV----AYSTDspehllNVPAGRMSAfpdDPDHFL 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205  71 -W---------PNRGESSFPT------YV-DVLDYLEAYAKHFNLVKFIkfNSKVVELRFIGDGktlqmgdlgaygnllp 133
Cdd:COG4529   77 rWlrengaraaPAIDPDAFVPrrlfgeYLrERLAEALARAPAGVRLRHI--RAEVVDLERDDGG---------------- 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205 134 gkpvweVAVNTGDGdiQWHAFEYVVVCAGkygdvprtpTFPVKKGPEIFKG--KVLHSM-DYSKLqkekaSQLLHGKKVA 210
Cdd:COG4529  139 ------YRVTLADG--ETLRADAVVLATG---------HPPPAPPPGLAAGspRYIADPwPPGAL-----ARIPPDARVL 196

                        250       260
                 ....*....|....*....|....*
gi 334188205 211 VIGFKKSAIDLALesALANQGKEGK 235
Cdd:COG4529  197 IIGTGLTAIDVVL--SLAARGHRGP 219
GltD COG0493
NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport ...
 12-213 1.05e-08

NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]; NADPH-dependent glutamate synthase beta chain or related oxidoreductase is part of the Pathway/BioSystem: Glutamine biosynthesis


Pssm-ID: 440259 [Multi-domain]  Cd Length: 434  Bit Score: 57.07  E-value: 1.05e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205  12 RVAIIGAGVSGLAAAKHLAR--HHPQVFEASDSIGGVwrkctyettklqsvrVSYELSDFLWPNrgessfptyvDVLD-- 87
Cdd:COG0493  123 KVAVVGSGPAGLAAAYQLARagHEVTVFEALDKPGGL---------------LRYGIPEFRLPK----------DVLDre 177

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205  88 --YLEAYAkhfnlVKFiKFNSKVvelrfigdGKTLQMGDLgaygnllpgkpvwevavntgdgdiqWHAFEYVVVCAGKYG 165
Cdd:COG0493  178 ieLIEALG-----VEF-RTNVEV--------GKDITLDEL-------------------------LEEFDAVFLATGAGK 218

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 334188205 166 dvPRTPTFPvkkGpEIFKGkVLHSMDY---SKLQKEKASQLLHGKKVAVIG 213
Cdd:COG0493  219 --PRDLGIP---G-EDLKG-VHSAMDFltaVNLGEAPDTILAVGKRVVVIG 262
PRK07233 PRK07233
hypothetical protein; Provisional
 12-45 1.37e-08

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 56.82  E-value: 1.37e-08
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 334188205  12 RVAIIGAGVSGLAAAKHLAR--HHPQVFEASDSIGG 45
Cdd:PRK07233   1 KIAIVGGGIAGLAAAYRLAKrgHEVTVFEADDQLGG 36
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 12-340 1.52e-07

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 52.71  E-value: 1.52e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205   12 RVAIIGAGVSGLAAAKHLARHHPQVfeasdSIGGVWRKCTYETTKLqsvrvSYELSDFLWPNRGESSFPTYVDVLDylea 91
Cdd:pfam07992   2 DVVVIGGGPAGLAAALTLAQLGGKV-----TLIEDEGTCPYGGCVL-----SKALLGAAEAPEIASLWADLYKRKE---- 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205   92 yAKHFNLVKFIKFNSKVVELRFIGDGKTLqmgdlgaygnllpgkpvweVAVNTGDGDIQWHAFEYVVVCAGKygdVPRTP 171
Cdd:pfam07992  68 -EVVKKLNNGIEVLLGTEVVSIDPGAKKV-------------------VLEELVDGDGETITYDRLVIATGA---RPRLP 124

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205  172 TFPVKKGPEIFKGKVLHSMDYSKLQKEkasqllhGKKVAVIGFKKSAIDLAleSALANQGKEgktCTMVVRTPHWVIPHy 251
Cdd:pfam07992 125 PIPGVELNVGFLVRTLDSAEALRLKLL-------PKRVVVVGGGYIGVELA--AALAKLGKE---VTLIEALDRLLRAF- 191

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205  252 wRATVSKFIESYvlwklpLEKYGLKpdhafeedyascqmaLVPEKFFEEADKGMIRFKRTTnwwfydegiefEDGTTLEA 331
Cdd:pfam07992 192 -DEEISAALEKA------LEKNGVE---------------VRLGTSVKEIIGDGDGVEVIL-----------KDGTEIDA 238


                  ....*....
gi 334188205  332 DVVILATGY 340
Cdd:pfam07992 239 DLVVVAIGR 247
gltD PRK12810
glutamate synthase subunit beta; Reviewed
 12-45 1.95e-07

glutamate synthase subunit beta; Reviewed


Pssm-ID: 237213 [Multi-domain]  Cd Length: 471  Bit Score: 53.24  E-value: 1.95e-07
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 334188205  12 RVAIIGAGVSGLAAAKHLAR--HHPQVFEASDSIGG 45
Cdd:PRK12810 145 KVAVVGSGPAGLAAADQLARagHKVTVFERADRIGG 180
COG3380 COG3380
Predicted NAD/FAD-dependent oxidoreductase [General function prediction only];
7-45 2.26e-07

Predicted NAD/FAD-dependent oxidoreductase [General function prediction only];


Pssm-ID: 442607 [Multi-domain]  Cd Length: 331  Bit Score: 52.57  E-value: 2.26e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 334188205   7 MHTSsRVAIIGAGVSGLAAAKHLAR--HHPQVFEASDSIGG 45
Cdd:COG3380    1 MSMP-DIAIIGAGIAGLAAARALQDagHEVTVFEKSRGVGG 40
PLN02576 PLN02576
protoporphyrinogen oxidase
 10-73 2.74e-07

protoporphyrinogen oxidase


Pssm-ID: 215314 [Multi-domain]  Cd Length: 496  Bit Score: 52.71  E-value: 2.74e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205  10 SSRVAIIGAGVSGLAAAKHLARHHPQ---VFEASDSIGGvwrkctyettKLQSVrvsyELSDFLW---PN 73
Cdd:PLN02576  12 SKDVAVVGAGVSGLAAAYALASKHGVnvlVTEARDRVGG----------NITSV----SEDGFIWeegPN 67
COG3349 COG3349
Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function ...
 9-45 7.17e-07

Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function prediction only];


Pssm-ID: 442577 [Multi-domain]  Cd Length: 445  Bit Score: 51.39  E-value: 7.17e-07
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 334188205   9 TSSRVAIIGAGVSGLAAAKHLAR--HHPQVFEASDSIGG 45
Cdd:COG3349    2 MPPRVVVVGGGLAGLAAAVELAEagFRVTLLEARPRLGG 40
PRK11883 PRK11883
protoporphyrinogen oxidase; Reviewed
 12-62 8.36e-07

protoporphyrinogen oxidase; Reviewed


Pssm-ID: 237009 [Multi-domain]  Cd Length: 451  Bit Score: 51.00  E-value: 8.36e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 334188205  12 RVAIIGAGVSGLAAAKHLARHHPQ----VFEASDSIGGvwrkctyettKLQSVRV 62
Cdd:PRK11883   2 KVAIIGGGITGLSAAYRLHKKGPDaditLLEASDRLGG----------KIQTVRK 46
PRK12771 PRK12771
putative glutamate synthase (NADPH) small subunit; Provisional
 9-48 1.87e-06

putative glutamate synthase (NADPH) small subunit; Provisional


Pssm-ID: 237198 [Multi-domain]  Cd Length: 564  Bit Score: 50.26  E-value: 1.87e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 334188205   9 TSSRVAIIGAGVSGLAAAKHLAR--HHPQVFEASDSIGGVWR 48
Cdd:PRK12771 136 TGKRVAVIGGGPAGLSAAYHLRRmgHAVTIFEAGPKLGGMMR 177
NAD_binding_9 pfam13454
FAD-NAD(P)-binding;
14-124 1.91e-06

FAD-NAD(P)-binding;


Pssm-ID: 433222 [Multi-domain]  Cd Length: 155  Bit Score: 47.66  E-value: 1.91e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205   14 AIIGAGVSGLAAAKHLARHHPQ------VFEASDS-IGGVWRK--CTYETTKLQSVRVSY---ELSDFL-W--------- 71
Cdd:pfam13454   1 AIVGGGPSGLALLERLLARAPKrpleitLFDPSPPgAGGVYRTdqSPEHLLNVPASRMSLfpdDPPHFLeWlrargalde 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 334188205   72 -PNRGESSFPTYVDVLDYLEAYAKHF-----NLVKFIKFNSKVVELRFIGDGKTLQMGD 124
Cdd:pfam13454  81 aPGLDPDDFPPRALYGRYLRDRFEEAlarapAGVTVRVHRARVTDLRPRGDGYRVLLAD 139
PRK11749 PRK11749
dihydropyrimidine dehydrogenase subunit A; Provisional
 9-46 2.84e-06

dihydropyrimidine dehydrogenase subunit A; Provisional


Pssm-ID: 236967 [Multi-domain]  Cd Length: 457  Bit Score: 49.41  E-value: 2.84e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 334188205   9 TSSRVAIIGAGVSGLAAAKHLARHHPQV--FEASDSIGGV 46
Cdd:PRK11749 139 TGKKVAVIGAGPAGLTAAHRLARKGYDVtiFEARDKAGGL 178
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
15-89 4.88e-06

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 44.06  E-value: 4.88e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 334188205   15 IIGAGVSGLAAAKHLAR--HHPQVFEASDSIGGVWRkctyeTTKLQSVRVSYELSDFLWPNRGESSfptyvDVLDYL 89
Cdd:pfam13450   1 IVGAGLAGLVAAALLAKrgFRVLVLEKRDRLGGNAY-----SYRVPGYVFDYGAHIFHGSDEPNVR-----DLLDEL 67
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 9-45 1.00e-05

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 47.92  E-value: 1.00e-05
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 334188205   9 TSSRVAIIGAGVSGLAAAKHLAR--HHPQVFEASDSIGG 45
Cdd:COG1233    2 MMYDVVVIGAGIGGLAAAALLARagYRVTVLEKNDTPGG 40
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 12-45 4.21e-05

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 45.47  E-value: 4.21e-05
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 334188205   12 RVAIIGAGVSGLAAAKHLARHHPQV--FEASDSIGG 45
Cdd:pfam01266   1 DVVVIGGGIVGLSTAYELARRGLSVtlLERGDDPGS 36
Amino_oxidase pfam01593
Flavin containing amine oxidoreductase; This family consists of various amine oxidases, ...
 20-125 5.19e-05

Flavin containing amine oxidoreductase; This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.


Pssm-ID: 396255 [Multi-domain]  Cd Length: 446  Bit Score: 45.56  E-value: 5.19e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205   20 VSGLAAAKHLARHHPQV--FEASDSIGGvwrkctyettklqsvRV-SYELSDFLWpNRGESSFPTYvdvLDYLEAYAKHF 96
Cdd:pfam01593   1 LAGLAAARELLRAGHDVtvLEARDRVGG---------------RIrTVRDDGFLI-ELGAMWFHGA---QPPLLALLKEL 61

                          90       100
                  ....*....|....*....|....*....
gi 334188205   97 NLVKFIKFNSKVVELRFIGDGKTLQMGDL 125
Cdd:pfam01593  62 GLEDRLVLPDPAPFYTVLFAGGRRYPGDF 90
NirB COG1251
NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];
10-339 9.37e-05

NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];


Pssm-ID: 440863 [Multi-domain]  Cd Length: 402  Bit Score: 44.36  E-value: 9.37e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205  10 SSRVAIIGAGVSGLAAAKHLARHHPQ----VFEAsdsiggvwrkctyETtklqsvRVSYE---LSDFLwpnRGESSF-PT 81
Cdd:COG1251    1 KMRIVIIGAGMAGVRAAEELRKLDPDgeitVIGA-------------EP------HPPYNrppLSKVL---AGETDEeDL 58

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205  82 YVDVLDYLEAyakhfNLVKFIkFNSKVVELRFigDGKTLQmgdlgaygnllpgkpvwevavnTGDGDIqwHAFEYVVVCA 161
Cdd:COG1251   59 LLRPADFYEE-----NGIDLR-LGTRVTAIDR--AARTVT----------------------LADGET--LPYDKLVLAT 106

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205 162 GKYgdvPRTPTFPVKKGPEIFkgkVLHSM-DYSKLQKEkasqLLHGKKVAVIG--FkksaidLALE--SALANQGKEgkt 236
Cdd:COG1251  107 GSR---PRVPPIPGADLPGVF---TLRTLdDADALRAA----LAPGKRVVVIGggL------IGLEaaAALRKRGLE--- 167

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205 237 CTMVVRTPHW---VIPhywrATVSKFIESYvlwklpLEKYGLKpdhafeedyascqmalvpekffeeadkgmIRFKRTTN 313
Cdd:COG1251  168 VTVVERAPRLlprQLD----EEAGALLQRL------LEALGVE-----------------------------VRLGTGVT 208

                        330       340
                 ....*....|....*....|....*....
gi 334188205 314 WWFYD---EGIEFEDGTTLEADVVILATG 339
Cdd:COG1251  209 EIEGDdrvTGVRLADGEELPADLVVVAIG 237
PRK07208 PRK07208
hypothetical protein; Provisional
 13-53 1.03e-04

hypothetical protein; Provisional


Pssm-ID: 235967 [Multi-domain]  Cd Length: 479  Bit Score: 44.49  E-value: 1.03e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 334188205  13 VAIIGAGVSGLAAAKHLAR--HHPQVFEASDSIGGVWRKCTYE 53
Cdd:PRK07208   7 VVIIGAGPAGLTAAYELLKrgYPVTVLEADPVVGGISRTVTYK 49
proto_IX_ox TIGR00562
protoporphyrinogen oxidase; This enzyme oxidizes protoporphyrinogen IX to protoporphyrin IX, a ...
 13-45 1.18e-04

protoporphyrinogen oxidase; This enzyme oxidizes protoporphyrinogen IX to protoporphyrin IX, a precursor of heme and chlorophyll. Bacillus subtilis HemY also has coproporphyrinogen III to coproporphyrin III oxidase activity in a heterologous expression system, although the role for this activity in vivo is unclear. This protein is a flavoprotein and has a beta-alpha-beta dinucleotide binding motif near the amino end. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin]


Pssm-ID: 213540 [Multi-domain]  Cd Length: 462  Bit Score: 44.44  E-value: 1.18e-04
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 334188205   13 VAIIGAGVSGLAAAKHLARHHPQ------VFEASDSIGG 45
Cdd:TIGR00562   5 VVIIGGGISGLCAAYYLEKEIPElpveltLVEASDRVGG 43
PRK12814 PRK12814
putative NADPH-dependent glutamate synthase small subunit; Provisional
 9-48 1.94e-04

putative NADPH-dependent glutamate synthase small subunit; Provisional


Pssm-ID: 139246 [Multi-domain]  Cd Length: 652  Bit Score: 43.95  E-value: 1.94e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 334188205   9 TSSRVAIIGAGVSGLAAAKHLAR--HHPQVFEASDSIGGVWR 48
Cdd:PRK12814 192 SGKKVAIIGAGPAGLTAAYYLLRkgHDVTIFDANEQAGGMMR 233
PRK12769 PRK12769
putative oxidoreductase Fe-S binding subunit; Reviewed
 9-45 5.23e-04

putative oxidoreductase Fe-S binding subunit; Reviewed


Pssm-ID: 183733 [Multi-domain]  Cd Length: 654  Bit Score: 42.43  E-value: 5.23e-04
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 334188205   9 TSSRVAIIGAGVSGLAAAKHLARH--HPQVFEASDSIGG 45
Cdd:PRK12769 326 SDKRVAIIGAGPAGLACADVLARNgvAVTVYDRHPEIGG 364
PLN02612 PLN02612
phytoene desaturase
 12-45 5.55e-04

phytoene desaturase


Pssm-ID: 215330 [Multi-domain]  Cd Length: 567  Bit Score: 42.52  E-value: 5.55e-04
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 334188205  12 RVAIIGAGVSGLAAAKHLAR--HHPQVFEASDSIGG 45
Cdd:PLN02612  95 KVVIAGAGLAGLSTAKYLADagHKPILLEARDVLGG 130
MurD COG0771
UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell wall/membrane/envelope biogenesis]; ...
 12-42 5.61e-04

UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramoylalanine-D-glutamate ligase is part of the Pathway/BioSystem: Mureine biosynthesis


Pssm-ID: 440534 [Multi-domain]  Cd Length: 445  Bit Score: 41.99  E-value: 5.61e-04
                         10        20        30
                 ....*....|....*....|....*....|.
gi 334188205  12 RVAIIGAGVSGLAAAKHLARHHPQVFeASDS 42
Cdd:COG0771    6 KVLVLGLGKSGLAAARLLAKLGAEVT-VSDD 35
PLN02676 PLN02676
polyamine oxidase
 9-49 7.73e-04

polyamine oxidase


Pssm-ID: 215362 [Multi-domain]  Cd Length: 487  Bit Score: 41.62  E-value: 7.73e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 334188205   9 TSSRVAIIGAGVSGLAAAKHLARHHPQ---VFEASDSIGGVWRK 49
Cdd:PLN02676  25 PSPSVIIVGAGMSGISAAKTLSEAGIEdilILEATDRIGGRMRK 68
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
9-41 7.94e-04

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 41.43  E-value: 7.94e-04
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 334188205   9 TSSRVAIIGAGVSGLAAAKHLAR--HHPQVFEASD 41
Cdd:COG0665    1 ATADVVVIGGGIAGLSTAYHLARrgLDVTVLERGR 35
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
12-54 1.52e-03

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 41.00  E-value: 1.52e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 334188205  12 RVAIIGAGVSGLAAAKHLARHHPQVF--EASDSIGGVWRK--CTYET 54
Cdd:COG1148  142 RALVIGGGIAGMTAALELAEQGYEVYlvEKEPELGGRAAQlhKTFPG 188
crtI_fam TIGR02734
phytoene desaturase; Phytoene is converted to lycopene by desaturation at four (two ...
 13-49 1.55e-03

phytoene desaturase; Phytoene is converted to lycopene by desaturation at four (two symmetrical pairs of) sites. This is achieved by two enzymes (crtP and crtQ) in cyanobacteria (Gloeobacter being an exception) and plants, but by a single enzyme in most other bacteria and in fungi. This single enzyme is called the bacterial-type phytoene desaturase, or CrtI. Most members of this family, part of the larger pfam01593, which also contains amino oxidases, are CrtI itself; it is likely that all members act on either phytoene or on related compounds such as dehydrosqualene, for carotenoid biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]


Pssm-ID: 274273 [Multi-domain]  Cd Length: 495  Bit Score: 40.72  E-value: 1.55e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 334188205   13 VAIIGAGVSGLAAAKHLAR--HHPQVFEASDSIGG---VWRK 49
Cdd:TIGR02734   1 AVVIGAGFGGLALAIRLAAagIPVTVVEQRDKPGGragVLED 42
PRK12778 PRK12778
bifunctional dihydroorotate dehydrogenase B NAD binding subunit/NADPH-dependent glutamate ...
 12-46 2.33e-03

bifunctional dihydroorotate dehydrogenase B NAD binding subunit/NADPH-dependent glutamate synthase;


Pssm-ID: 237200 [Multi-domain]  Cd Length: 752  Bit Score: 40.50  E-value: 2.33e-03
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 334188205  12 RVAIIGAGVSGLAAAKHLAR--HHPQVFEASDSIGGV 46
Cdd:PRK12778 433 KVAVIGSGPAGLSFAGDLAKrgYDVTVFEALHEIGGV 469
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 12-124 7.27e-03

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 38.38  E-value: 7.27e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188205  12 RVAIIGAGVSGLAAAKHLAR--HHPQVFEASDSIG-------------------GVWRKCTYETTKLQSVRVSY-----E 65
Cdd:COG0654    5 DVLIVGGGPAGLALALALARagIRVTVVERAPPPRpdgrgialsprslellrrlGLWDRLLARGAPIRGIRVRDgsdgrV 84

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 334188205  66 LSDFlwpNRGESSFPTYV-----DVLDYLEAYAKHFNLVkfIKFNSKVVELRFIGDGKTLQMGD 124
Cdd:COG0654   85 LARF---DAAETGLPAGLvvpraDLERALLEAARALGVE--LRFGTEVTGLEQDADGVTVTLAD 143
PRK08163 PRK08163
3-hydroxybenzoate 6-monooxygenase;
7-44 9.92e-03

3-hydroxybenzoate 6-monooxygenase;


Pssm-ID: 181262 [Multi-domain]  Cd Length: 396  Bit Score: 38.09  E-value: 9.92e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 334188205   7 MHTSSRVAIIGAGVSGLAAAKHLAR--HHPQVFEASDSIG 44
Cdd:PRK08163   1 MTKVTPVLIVGGGIGGLAAALALARqgIKVKLLEQAAEIG 40
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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