|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
100-634 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 672.82 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 100 RVVTPRELLSDFIGSMVCVEGIVTKCSLVRPKVVKS---VHFCPSTGEFTNRDYRDITSHAGLPTGSVYPTRddkgnlLV 176
Cdd:smart00350 1 KPSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRAsftCEKCGATLGPEIQSGRETEPTVCPPRECQSPTP------FS 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 177 TEYGLCKYKDHQTLSIQEVPENAAPGQLPRSVDVIAEDDLVDSCKPGDRVSVFGIYKALP-GKSKGSVNG--VFRTILIA 253
Cdd:smart00350 75 LNHERSTFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVPyGFKLNTVKGlpVFATYIEA 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 254 NNIALLNK-------EANAPIYTKQDLDNIKNIARRDDAFDLLARSLAPSIYGHAWIKKAVVLLMLGGVEKNLKNGTHLR 326
Cdd:smart00350 155 NHVRKLDYkrsfedsSFSVQSLSDEEEEEIRKLSKDPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLPDGMKIR 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 327 GDINMMMVGDPSVAKSQLLRAIMNIAPLAISTTGRGSSGVGLTAAVTSDQETGERRLEAGAMVLADKGIVCIDEFDKMND 406
Cdd:smart00350 235 GDINILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEFDKMDD 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 407 QDRVAIHEVMEQQTVTIAKAGIHASLNARCSVVAAANPIYGTYDRSLTPTKNIGLPDSLLSRFDLLFIVLDQMDAGIDSM 486
Cdd:smart00350 315 SDRTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERDRE 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 487 ISEHVLRMHRYKNDRGEAGPDGSLPyarednaesemfvkynqtlhgkkkrgqthdktltIKFLKKYIHYAKHRITPKLTD 566
Cdd:smart00350 395 LAKHVVDLHRYSHPEEDEAFEPPLS----------------------------------QEKLRKYIAYAREKIKPKLSE 440
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15237411 567 EASERIAEAYADLRNAGSDTKTGGTLPITARTLETIIRLATAHAKMKLSSEVTKADAEAALKLMNFAI 634
Cdd:smart00350 441 EAADKLVKAYVDLRKEDSQTESRSSIPITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIRLLRESI 508
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
15-630 |
0e+00 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 588.69 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 15 FIQFLDS-MYMEEIKALVHQKRHR--LIINISDIHHHFREVASRILKNPNEYMqsfcDAATEATRAIDP-KYLKEGELVL 90
Cdd:COG1241 9 FEEFLRRyKYRDEILELAQEYPEKrsLVVDYNDLYSFDPDLADDLLENPDEVL----EAAEEALREIDLePYDVSLGDAH 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 91 VGFEGYFvsRVVTPRELLSDFIGSMVCVEGIVTKCSLVRPKVVKSVHFCPSTGEFT--NRDYRDITshaglptgsvYPTR 168
Cdd:COG1241 85 VRITNLP--ETVPIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRCGTETyvPQTGEKLQ----------EPHE 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 169 ----DDKGNL-LVTEygLCKYKDHQTLSIQEVPENAAPGQLPRSVDVIAEDDLVDSCKPGDRVSVFGIYKALPGKSKGSV 243
Cdd:COG1241 153 cpgcGRQGPFkLLPE--KSEFIDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGILRIEQRTSGRGK 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 244 NGVFRTILIANNIALLNKEANAPIYTKQDLDNIKNIARRDDAFDLLARSLAPSIYGHAWIKKAVVLLMLGGVEKNLKNGT 323
Cdd:COG1241 231 STIFDLYLEANSIEVEEKEFEEIEITEEDEEKIKELSKDPDIYEKIIASIAPSIYGYEEIKEAIALQLFGGVPKVLPDGS 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 324 HLRGDINMMMVGDPSVAKSQLLRAIMNIAPLAISTTGRGSSGVGLTAAVTSDQE-TGERRLEAGAMVLADKGIVCIDEFD 402
Cdd:COG1241 311 RIRGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAVRDDFgTGRWTLEAGALVLADGGLACIDELD 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 403 KMNDQDRVAIHEVMEQQTVTIAKAGIHASLNARCSVVAAANPIYGTYDRSLTPTKNIGLPDSLLSRFDLLFIVLDQMDAG 482
Cdd:COG1241 391 KMREEDRSALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGRFDPYEPIAEQIDLPPTLLSRFDLIFVLRDKPDEE 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 483 IDSMISEHVLRMHRykndrgEAGPDGSLPYAREDNAESEMfvkynqtlhgkkkrgqthDKTLtikfLKKYIHYAKHRITP 562
Cdd:COG1241 471 RDRELARHILKVHR------AGELLEQEIEEETEEVKPEI------------------DPDL----LRKYIAYARRNVFP 522
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15237411 563 KLTDEASERIAEAYADLRNAGSDtkTGGTLPITARTLETIIRLATAHAKMKLSSEVTKADAEAALKLM 630
Cdd:COG1241 523 VLTEEAKDLIEDFYVDMRKKGED--EDSPVPITARQLEALIRLAEASARMRLSDTVTEEDAERAIRLV 588
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
13-630 |
0e+00 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 566.86 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 13 RDFIQ-FLDSM----YMEEIKALVHQKRHRLIINISDIHHHFREVASRILKNPNEYMQSFCDAATEATRAIDPKYLKEGE 87
Cdd:NF040949 6 KEFIRtFRDSFgnekYKERIFEMIAMRKRSLVVDFNDLYMFDPELADLLIEKPDEVLPAASKALKEIVEEEDPEYAEEVA 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 88 LVLVGFEGyfVSRVVTPRELLSDFIGSMVCVEGIVTKCSLVRPKVVKSVHFCPSTG-EFtnrdyrditshaglptgsVYP 166
Cdd:NF040949 86 KFHVRFRN--LPRTVPLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCGcEF------------------EWP 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 167 TRDDKGNLLVTEYGLC----------------KYKDHQTLSIQEVPENAAPGQLPRSVDVIAEDDLVDSCKPGDRVSVFG 230
Cdd:NF040949 146 EEEEESYEIVEPPTVCpvcgkpgsfrllqeksKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTG 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 231 IYKALPGKS--KGSvNGVFRTILIANNIALLNKEANAPIYTKQDLDNIKNIARRDDAFDLLARSLAPSIYGHAWIKKAVV 308
Cdd:NF040949 226 ILRIKPDSSlkKGS-RPIFKNYIEANHIEVSQKELEEVEITEEDEEKILELAKDPWIREKIIASIAPSIYGHWEIKEAIA 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 309 LLMLGGVEKNLKNGTHLRGDINMMMVGDPSVAKSQLLRAIMNIAPLAISTTGRGSSGVGLTAAVTSDQETGERRLEAGAM 388
Cdd:NF040949 305 LLLFGGVPKVLPDGTRIRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRDKLTGEYYLEAGAL 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 389 VLADKGIVCIDEFDKMNDQDRVAIHEVMEQQTVTIAKAGIHASLNARCSVVAAANPIYGTYDRSLTPTKNIGLPDSLLSR 468
Cdd:NF040949 385 VLADGGVAVIDEIDKMREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFGRYDPNRSVAENIDLPPTILSR 464
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 469 FDLLFIVLDQMDAGIDSMISEHVLRMHRYKND-RGEAGPDgslpyarednaesemfvkynqtlhgkkkrgqthdktltik 547
Cdd:NF040949 465 FDLIFVIRDKPNEERDRRLARHILDVHSGKEKvKPEIDPD---------------------------------------- 504
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 548 FLKKYIHYAKHRITPKLTDEASERIAEAYADLRN-AGSDTKTGGTLPITARTLETIIRLATAHAKMKLSSEVTKADAEAA 626
Cdd:NF040949 505 LLKKYIAYARKYVRPKLTEEAKKLIEDFYVEMRKsSKSSEDPDSPIPITARQLEALIRLSEAHAKMRLKDEVTAEDAERA 584
|
....
gi 15237411 627 LKLM 630
Cdd:NF040949 585 IRLM 588
|
|
| MCM3 |
cd17754 |
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in ... |
288-633 |
0e+00 |
|
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350660 [Multi-domain] Cd Length: 299 Bit Score: 555.54 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 288 LLARSLAPSIYGHAWIKKAVVLLMLGGVEKNLKNGTHLRGDINMMMVGDPSVAKSQLLRAIMNIAPLAISTTGRGSSGVG 367
Cdd:cd17754 1 LLSKSLAPSIYGHEYIKKAILLMLLGGVEKNLENGSHLRGDINILLVGDPSVAKSQLLRYVLNTAPLAIATTGRGSSGVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 368 LTAAVTSDQETGERRLEAGAMVLADKGIVCIDEFDKMNDQDRVAIHEVMEQQTVTIAKAGIHASLNARCSVVAAANPIYG 447
Cdd:cd17754 81 LTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRVAIHEVMEQQTVTIAKAGIHASLNARCSVLAAANPVYG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 448 TYDRSLTPTKNIGLPDSLLSRFDLLFIVLDQMDAGIDSMISEHVLRMHRYkndrgeagpdgslpyarednaesemfvkyn 527
Cdd:cd17754 161 RYDVYKTPMENIGLPDSLLSRFDLLFIVLDDIDEERDRSISEHVLRMHRY------------------------------ 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 528 qtlhgkkkrgqthdktltIKFLKKYIHYAKHRITPKLTDEASERIAEAYADLRNAGSDTK-TGGTLPITARTLETIIRLA 606
Cdd:cd17754 211 ------------------IKFLRKYIHYAKERIKPKLTQEAAEYIAEEYADLRNDDNTKTdKARTSPITARTLETLIRLA 272
|
330 340
....*....|....*....|....*..
gi 15237411 607 TAHAKMKLSSEVTKADAEAALKLMNFA 633
Cdd:cd17754 273 TAHAKARLSKTVDKVDAEVALNLLRFA 299
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
272-495 |
5.07e-127 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 378.03 E-value: 5.07e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 272 DLDNIKNIARRDDAFDLLARSLAPSIYGHAWIKKAVVLLMLGGVEKNLKNGTHLRGDINMMMVGDPSVAKSQLLRAIMNI 351
Cdd:pfam00493 1 DEEEIKELAKRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVEKI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 352 APLAISTTGRGSSGVGLTAAVTSDQETGERRLEAGAMVLADKGIVCIDEFDKMNDQDRVAIHEVMEQQTVTIAKAGIHAS 431
Cdd:pfam00493 81 APRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIVAT 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15237411 432 LNARCSVVAAANPIYGTYDRSLTPTKNIGLPDSLLSRFDLLFIVLDQMDAGIDSMISEHVLRMH 495
Cdd:pfam00493 161 LNARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
103-636 |
9.58e-88 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 296.52 E-value: 9.58e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 103 TPRELLSDFIGSMVCVEGIVTKCSLVRPKVVKSVHFCPSTGEFTNRDYRDITSH------AGLPTGSVYPTRDDKGNLLV 176
Cdd:PTZ00111 217 CVGNLEPSMADSLVQFSGTVVRQTWIVPEITMACFRCRGQKKIGLNDYQPCTCEhyeyviQGEVNEPLLCNECNSKYTFE 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 177 TEYGLCKYKDHQTLSIQEVPENAAPGQLP--------------------RSVDVIAEDDLVDSCKPGDRVSVFGIYKALP 236
Cdd:PTZ00111 297 LNHNMCVYSTKKIVKLLQSNSSLNNPDKDgldnsvdnsglngeiymkdnEVINLNLYDDLIDSVKTGDRVTVVGILKVTP 376
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 237 ---GKSKGSVNGVFRTILIANNIALLNK-EANAPI-----------YTKQDLDNIKNIARRDDAFDLLARSLAPSIYGHA 301
Cdd:PTZ00111 377 irtSTTRRTLKSLYTYFVNVIHVKVINStNANQPEkglkylgnendFSDLQVYKILELSRNPMIYRILLDSFAPSIKARN 456
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 302 WIKKAVVLLMLGGVEKNLKNGT---------HLRGDINMMMVGDPSVAKSQLLRAIMNIAPLAISTTGRGSSGVGLTAAV 372
Cdd:PTZ00111 457 NVKIGLLCQLFSGNKNSSDFNKspdacykvdNFRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSVGLTASI 536
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 373 T-SDQETGERRLEAGAMVLADKGIVCIDEFDKMNDQDRVAIHEVMEQQTVTIAKAGIHASLNARCSVVAAANPIYGTYDR 451
Cdd:PTZ00111 537 KfNESDNGRAMIQPGAVVLANGGVCCIDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAILASCNPINSRYNK 616
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 452 SLTPTKNIGLPDSLLSRFDLLFIVLDQMDAGIDSMISEHVLRmhrykndrgeagpDGSLPYAREDNAESEMFVKYNqTLH 531
Cdd:PTZ00111 617 NKAVIENINISPSLFTRFDLIYLVLDHIDQDTDQLISLSIAK-------------DFLLPHMTGSGNDEDTYDRSN-TMH 682
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 532 GKKK--RGQTHDKTLTIKFLKKYIHYAKHRITPKLTDEASERIAEAYADLRNAGSDT--------------------KTG 589
Cdd:PTZ00111 683 VEDEslRSEKDYNKNDLDMLRMYIKFSKLHCFPKLSDEAKKVITREYVKMRQGNFQTsnldelehaqedddddlyyqSSG 762
|
570 580 590 600
....*....|....*....|....*....|....*....|....*...
gi 15237411 590 GTLP-ITARTLETIIRLATAHAKMKLSSEVTKADAEAALKLMNFAIYH 636
Cdd:PTZ00111 763 TRMIyVSSRMISSIIRISVSLARMRLSTVVTPADALQAVQIVKSSTFQ 810
|
|
| MCM_N |
pfam14551 |
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins. |
12-95 |
2.08e-11 |
|
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.
Pssm-ID: 464206 [Multi-domain] Cd Length: 95 Bit Score: 60.77 E-value: 2.08e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 12 KRDFIQFLDS---------MYMEEIKALVHQKRHRLIINISDIHHHFREVASRILKNPNEYMQSFCDAATEATRAI--DP 80
Cdd:pfam14551 1 KRKFKDFLEEfredgdgefKYRDQLREMIEREQRSLEVDLDDLREFDPDLAEALLENPYEYLPLFEEALKEVVKELseDP 80
|
90
....*....|....*
gi 15237411 81 KYLKEGELVLVGFEG 95
Cdd:pfam14551 81 DYAEEEKEFQVRFYN 95
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
100-634 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 672.82 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 100 RVVTPRELLSDFIGSMVCVEGIVTKCSLVRPKVVKS---VHFCPSTGEFTNRDYRDITSHAGLPTGSVYPTRddkgnlLV 176
Cdd:smart00350 1 KPSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRAsftCEKCGATLGPEIQSGRETEPTVCPPRECQSPTP------FS 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 177 TEYGLCKYKDHQTLSIQEVPENAAPGQLPRSVDVIAEDDLVDSCKPGDRVSVFGIYKALP-GKSKGSVNG--VFRTILIA 253
Cdd:smart00350 75 LNHERSTFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVPyGFKLNTVKGlpVFATYIEA 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 254 NNIALLNK-------EANAPIYTKQDLDNIKNIARRDDAFDLLARSLAPSIYGHAWIKKAVVLLMLGGVEKNLKNGTHLR 326
Cdd:smart00350 155 NHVRKLDYkrsfedsSFSVQSLSDEEEEEIRKLSKDPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLPDGMKIR 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 327 GDINMMMVGDPSVAKSQLLRAIMNIAPLAISTTGRGSSGVGLTAAVTSDQETGERRLEAGAMVLADKGIVCIDEFDKMND 406
Cdd:smart00350 235 GDINILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEFDKMDD 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 407 QDRVAIHEVMEQQTVTIAKAGIHASLNARCSVVAAANPIYGTYDRSLTPTKNIGLPDSLLSRFDLLFIVLDQMDAGIDSM 486
Cdd:smart00350 315 SDRTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERDRE 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 487 ISEHVLRMHRYKNDRGEAGPDGSLPyarednaesemfvkynqtlhgkkkrgqthdktltIKFLKKYIHYAKHRITPKLTD 566
Cdd:smart00350 395 LAKHVVDLHRYSHPEEDEAFEPPLS----------------------------------QEKLRKYIAYAREKIKPKLSE 440
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15237411 567 EASERIAEAYADLRNAGSDTKTGGTLPITARTLETIIRLATAHAKMKLSSEVTKADAEAALKLMNFAI 634
Cdd:smart00350 441 EAADKLVKAYVDLRKEDSQTESRSSIPITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIRLLRESI 508
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
15-630 |
0e+00 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 588.69 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 15 FIQFLDS-MYMEEIKALVHQKRHR--LIINISDIHHHFREVASRILKNPNEYMqsfcDAATEATRAIDP-KYLKEGELVL 90
Cdd:COG1241 9 FEEFLRRyKYRDEILELAQEYPEKrsLVVDYNDLYSFDPDLADDLLENPDEVL----EAAEEALREIDLePYDVSLGDAH 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 91 VGFEGYFvsRVVTPRELLSDFIGSMVCVEGIVTKCSLVRPKVVKSVHFCPSTGEFT--NRDYRDITshaglptgsvYPTR 168
Cdd:COG1241 85 VRITNLP--ETVPIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRCGTETyvPQTGEKLQ----------EPHE 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 169 ----DDKGNL-LVTEygLCKYKDHQTLSIQEVPENAAPGQLPRSVDVIAEDDLVDSCKPGDRVSVFGIYKALPGKSKGSV 243
Cdd:COG1241 153 cpgcGRQGPFkLLPE--KSEFIDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGILRIEQRTSGRGK 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 244 NGVFRTILIANNIALLNKEANAPIYTKQDLDNIKNIARRDDAFDLLARSLAPSIYGHAWIKKAVVLLMLGGVEKNLKNGT 323
Cdd:COG1241 231 STIFDLYLEANSIEVEEKEFEEIEITEEDEEKIKELSKDPDIYEKIIASIAPSIYGYEEIKEAIALQLFGGVPKVLPDGS 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 324 HLRGDINMMMVGDPSVAKSQLLRAIMNIAPLAISTTGRGSSGVGLTAAVTSDQE-TGERRLEAGAMVLADKGIVCIDEFD 402
Cdd:COG1241 311 RIRGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAVRDDFgTGRWTLEAGALVLADGGLACIDELD 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 403 KMNDQDRVAIHEVMEQQTVTIAKAGIHASLNARCSVVAAANPIYGTYDRSLTPTKNIGLPDSLLSRFDLLFIVLDQMDAG 482
Cdd:COG1241 391 KMREEDRSALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGRFDPYEPIAEQIDLPPTLLSRFDLIFVLRDKPDEE 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 483 IDSMISEHVLRMHRykndrgEAGPDGSLPYAREDNAESEMfvkynqtlhgkkkrgqthDKTLtikfLKKYIHYAKHRITP 562
Cdd:COG1241 471 RDRELARHILKVHR------AGELLEQEIEEETEEVKPEI------------------DPDL----LRKYIAYARRNVFP 522
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15237411 563 KLTDEASERIAEAYADLRNAGSDtkTGGTLPITARTLETIIRLATAHAKMKLSSEVTKADAEAALKLM 630
Cdd:COG1241 523 VLTEEAKDLIEDFYVDMRKKGED--EDSPVPITARQLEALIRLAEASARMRLSDTVTEEDAERAIRLV 588
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
13-630 |
0e+00 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 566.86 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 13 RDFIQ-FLDSM----YMEEIKALVHQKRHRLIINISDIHHHFREVASRILKNPNEYMQSFCDAATEATRAIDPKYLKEGE 87
Cdd:NF040949 6 KEFIRtFRDSFgnekYKERIFEMIAMRKRSLVVDFNDLYMFDPELADLLIEKPDEVLPAASKALKEIVEEEDPEYAEEVA 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 88 LVLVGFEGyfVSRVVTPRELLSDFIGSMVCVEGIVTKCSLVRPKVVKSVHFCPSTG-EFtnrdyrditshaglptgsVYP 166
Cdd:NF040949 86 KFHVRFRN--LPRTVPLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCGcEF------------------EWP 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 167 TRDDKGNLLVTEYGLC----------------KYKDHQTLSIQEVPENAAPGQLPRSVDVIAEDDLVDSCKPGDRVSVFG 230
Cdd:NF040949 146 EEEEESYEIVEPPTVCpvcgkpgsfrllqeksKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTG 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 231 IYKALPGKS--KGSvNGVFRTILIANNIALLNKEANAPIYTKQDLDNIKNIARRDDAFDLLARSLAPSIYGHAWIKKAVV 308
Cdd:NF040949 226 ILRIKPDSSlkKGS-RPIFKNYIEANHIEVSQKELEEVEITEEDEEKILELAKDPWIREKIIASIAPSIYGHWEIKEAIA 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 309 LLMLGGVEKNLKNGTHLRGDINMMMVGDPSVAKSQLLRAIMNIAPLAISTTGRGSSGVGLTAAVTSDQETGERRLEAGAM 388
Cdd:NF040949 305 LLLFGGVPKVLPDGTRIRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRDKLTGEYYLEAGAL 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 389 VLADKGIVCIDEFDKMNDQDRVAIHEVMEQQTVTIAKAGIHASLNARCSVVAAANPIYGTYDRSLTPTKNIGLPDSLLSR 468
Cdd:NF040949 385 VLADGGVAVIDEIDKMREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFGRYDPNRSVAENIDLPPTILSR 464
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 469 FDLLFIVLDQMDAGIDSMISEHVLRMHRYKND-RGEAGPDgslpyarednaesemfvkynqtlhgkkkrgqthdktltik 547
Cdd:NF040949 465 FDLIFVIRDKPNEERDRRLARHILDVHSGKEKvKPEIDPD---------------------------------------- 504
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 548 FLKKYIHYAKHRITPKLTDEASERIAEAYADLRN-AGSDTKTGGTLPITARTLETIIRLATAHAKMKLSSEVTKADAEAA 626
Cdd:NF040949 505 LLKKYIAYARKYVRPKLTEEAKKLIEDFYVEMRKsSKSSEDPDSPIPITARQLEALIRLSEAHAKMRLKDEVTAEDAERA 584
|
....
gi 15237411 627 LKLM 630
Cdd:NF040949 585 IRLM 588
|
|
| MCM3 |
cd17754 |
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in ... |
288-633 |
0e+00 |
|
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350660 [Multi-domain] Cd Length: 299 Bit Score: 555.54 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 288 LLARSLAPSIYGHAWIKKAVVLLMLGGVEKNLKNGTHLRGDINMMMVGDPSVAKSQLLRAIMNIAPLAISTTGRGSSGVG 367
Cdd:cd17754 1 LLSKSLAPSIYGHEYIKKAILLMLLGGVEKNLENGSHLRGDINILLVGDPSVAKSQLLRYVLNTAPLAIATTGRGSSGVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 368 LTAAVTSDQETGERRLEAGAMVLADKGIVCIDEFDKMNDQDRVAIHEVMEQQTVTIAKAGIHASLNARCSVVAAANPIYG 447
Cdd:cd17754 81 LTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRVAIHEVMEQQTVTIAKAGIHASLNARCSVLAAANPVYG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 448 TYDRSLTPTKNIGLPDSLLSRFDLLFIVLDQMDAGIDSMISEHVLRMHRYkndrgeagpdgslpyarednaesemfvkyn 527
Cdd:cd17754 161 RYDVYKTPMENIGLPDSLLSRFDLLFIVLDDIDEERDRSISEHVLRMHRY------------------------------ 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 528 qtlhgkkkrgqthdktltIKFLKKYIHYAKHRITPKLTDEASERIAEAYADLRNAGSDTK-TGGTLPITARTLETIIRLA 606
Cdd:cd17754 211 ------------------IKFLRKYIHYAKERIKPKLTQEAAEYIAEEYADLRNDDNTKTdKARTSPITARTLETLIRLA 272
|
330 340
....*....|....*....|....*..
gi 15237411 607 TAHAKMKLSSEVTKADAEAALKLMNFA 633
Cdd:cd17754 273 TAHAKARLSKTVDKVDAEVALNLLRFA 299
|
|
| MCM |
cd17706 |
MCM helicase family; MCM helicases are a family of helicases that play an important role in ... |
288-633 |
1.14e-141 |
|
MCM helicase family; MCM helicases are a family of helicases that play an important role in replication and homologous recombination repair. The heterohexameric ring-shaped Mcm2-7 complex is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases. Mcm8 and Mcm9, form a complex required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350658 [Multi-domain] Cd Length: 311 Bit Score: 419.06 E-value: 1.14e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 288 LLARSLAPSIYGHAWIKKAVVLLMLGGVEKNLKNGTHLRGDINMMMVGDPSVAKSQLLRAIMNIAPLAISTTGRGSSGVG 367
Cdd:cd17706 1 ILADSIAPSIYGHEDVKKAVLLQLFGGVQKILEDGTRIRGDIHILLVGDPGTAKSQILKYVLKIAPRGVYTSGKGSSGAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 368 LTAAVTSDQETGERRLEAGAMVLADKGIVCIDEFDKMNDQDRVAIHEVMEQQTVTIAKAGIHASLNARCSVVAAANPIYG 447
Cdd:cd17706 81 LTAAVVRDSETGEWYLEAGALVLADGGVCCIDEFDKMKELDRTALHEAMEQQTISIAKAGIVTTLNARCSILAAANPKGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 448 TYDRSLTPTKNIGLPDSLLSRFDLLFIVLDQMDAGIDSMISEHVLRMHRYKNDrgeagpdgslpyAREDNAESEmfvkyn 527
Cdd:cd17706 161 RYNPKLSPIENINLPSPLLSRFDLIFVIRDDPDEERDEELAEHIIDLHRGSDP------------EEQVKPEED------ 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 528 qtlhgkkkrgqthDKTLTIKFLKKYIHYAKhRITPKLTDEASERIAEAYADLRNagsDTKTGGTLPITARTLETIIRLAT 607
Cdd:cd17706 223 -------------GIPIDIELLRKYILYAR-QIHPKISEEAREKLVRWYVELRK---ESERRSTIPITARQLESVIRLAE 285
|
330 340
....*....|....*....|....*.
gi 15237411 608 AHAKMKLSSEVTKADAEAALKLMNFA 633
Cdd:cd17706 286 AHAKMRLSEVVTEEDVEEAIRLVRHS 311
|
|
| MCM5 |
cd17756 |
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in ... |
288-629 |
1.86e-127 |
|
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350662 [Multi-domain] Cd Length: 317 Bit Score: 382.89 E-value: 1.86e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 288 LLARSLAPSIYGHAWIKKAVVLLMLGGVEKNLKNGTHLRGDINMMMVGDPSVAKSQLLRAIMNIAPLAISTTGRGSSGVG 367
Cdd:cd17756 1 IISKSIAPSIYGNEDIKKAIACLLFGGSRKRLPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 368 LTAAVTSDQETGERRLEAGAMVLADKGIVCIDEFDKMNDQDRVAIHEVMEQQTVTIAKAGIHASLNARCSVVAAANPIYG 447
Cdd:cd17756 81 LTASVMRDPSTREFYLEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRTSVLAAANPVFG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 448 TYDRSLTPTKNIGLPDSLLSRFDLLFIVLDQMDAGIDSMISEHVLRMHRykndrgeagpdGSLPYAREDNAESEmfvkyn 527
Cdd:cd17756 161 RYDDLKTPGDNIDFQTTILSRFDMIFIVKDKHDEERDITIAKHVINIHA-----------SARKASQSQENEGE------ 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 528 qtlhgkkkrgqthdktLTIKFLKKYIHYAKHRITPKLTDEASERIAEAY----ADLRNAGSDTKTGGTLPITARTLETII 603
Cdd:cd17756 224 ----------------IPISKLKRYIAYCRAKCAPRLSEEAAEKLSNHYvtirKDVRQNELESDNRSSIPITVRQLEAII 287
|
330 340
....*....|....*....|....*.
gi 15237411 604 RLATAHAKMKLSSEVTKADAEAALKL 629
Cdd:cd17756 288 RISESLAKMELSPIATEKHVEEAIRL 313
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
272-495 |
5.07e-127 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 378.03 E-value: 5.07e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 272 DLDNIKNIARRDDAFDLLARSLAPSIYGHAWIKKAVVLLMLGGVEKNLKNGTHLRGDINMMMVGDPSVAKSQLLRAIMNI 351
Cdd:pfam00493 1 DEEEIKELAKRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVEKI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 352 APLAISTTGRGSSGVGLTAAVTSDQETGERRLEAGAMVLADKGIVCIDEFDKMNDQDRVAIHEVMEQQTVTIAKAGIHAS 431
Cdd:pfam00493 81 APRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIVAT 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15237411 432 LNARCSVVAAANPIYGTYDRSLTPTKNIGLPDSLLSRFDLLFIVLDQMDAGIDSMISEHVLRMH 495
Cdd:pfam00493 161 LNARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| MCM_arch |
cd17761 |
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the ... |
287-630 |
2.74e-124 |
|
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the eukaryotic Mcm2-7 helicase and also function as the replicative helicase at the replication fork
Pssm-ID: 350667 [Multi-domain] Cd Length: 308 Bit Score: 374.48 E-value: 2.74e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 287 DLLARSLAPSIYGHAWIKKAVVLLMLGGVEKNLKNGTHLRGDINMMMVGDPSVAKSQLLRAIMNIAPLAISTTGRGSSGV 366
Cdd:cd17761 1 EKIISSIAPSIYGHEDVKEAIALQLFGGVPKVLPDGTRIRGDIHILLVGDPGTAKSQLLKYVSKVAPRAVYTTGKGSTAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 367 GLTAAVTSDQETGERRLEAGAMVLADKGIVCIDEFDKMNDQDRVAIHEVMEQQTVTIAKAGIHASLNARCSVVAAANPIY 446
Cdd:cd17761 81 GLTAAVVRDEGTGEWYLEAGALVLADKGIAVVDEIDKMRKEDRSALHEAMEQQTISIAKAGIVATLNARAAVLAAANPKF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 447 GTYDRSLTPTKNIGLPDSLLSRFDLLFIVLDQMDAGIDSMISEHVLRMHrykndrgeagpdgslpyarednAESEMFVKY 526
Cdd:cd17761 161 GRFDSYRPVAEQIDLPPTLLSRFDLIFVLKDTPNEEKDRRLANHILDTH----------------------SGGEMREIK 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 527 NQtlhgkkkrgqthdktLTIKFLKKYIHYAKHRITPKLTDEASERIAEAYADLRNAGSDTKTggTLPITARTLETIIRLA 606
Cdd:cd17761 219 PE---------------IDPDLLRKYIAYARKNVRPVLTEEAKQLIKDFYVEMRKSGQETPS--PVPITARQLEALVRLS 281
|
330 340
....*....|....*....|....
gi 15237411 607 TAHAKMKLSSEVTKADAEAALKLM 630
Cdd:cd17761 282 EASARMRLSQEVTLEDAERAIRIM 305
|
|
| MCM2 |
cd17753 |
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in ... |
292-630 |
1.79e-121 |
|
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350659 [Multi-domain] Cd Length: 325 Bit Score: 367.54 E-value: 1.79e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 292 SLAPSIYGHAWIKKAVVLLMLGGVEKNLKNGTHLRGDINMMMVGDPSVAKSQLLRAIMNIAPLAISTTGRGSSGVGLTAA 371
Cdd:cd17753 5 SIAPSIYGHDDIKTAIALALFGGVAKNPGGKHRIRGDINVLLLGDPGTAKSQFLKYVEKTAHRAVFTTGQGASAVGLTAS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 372 VTSDQETGERRLEAGAMVLADKGIVCIDEFDKMNDQDRVAIHEVMEQQTVTIAKAGIHASLNARCSVVAAANPIYGTYDR 451
Cdd:cd17753 85 VRKDPVTKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCSVIAAANPIGGRYNP 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 452 SLTPTKNIGLPDSLLSRFDLLFIVLDQMDAGIDSMISEHVLRMHRykndRGEAGPDgslpyareDNAESEMFVKYNQTLH 531
Cdd:cd17753 165 TLTFAQNVNLTEPILSRFDILCVVRDTVDPEEDERLAKFVVGSHV----RSHPEND--------EDREGEEEKNQRQRPK 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 532 GKKKRGQTHDktltikFLKKYIHYAKHRITPKLTDEASERIAEAYADLRNagsDTKTGGTLPITARTLETIIRLATAHAK 611
Cdd:cd17753 233 ETKVEPIPQE------LLRKYIHYAREKVRPKLNQMDMDKVSRVYADLRK---ESMATGSLPITVRHLESIIRISEAHAK 303
|
330
....*....|....*....
gi 15237411 612 MKLSSEVTKADAEAALKLM 630
Cdd:cd17753 304 MHLREYVSEEDVDMAIRVM 322
|
|
| MCM6 |
cd17757 |
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in ... |
289-631 |
5.41e-120 |
|
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350663 [Multi-domain] Cd Length: 307 Bit Score: 363.23 E-value: 5.41e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 289 LARSLAPSIYGHAWIKKAVVLLMLGGVEKNLKNGTHLRGDINMMMVGDPSVAKSQLLRAIMNIAPLAISTTGRGSSGVGL 368
Cdd:cd17757 2 LVRSIAPSIYGHEEVKKGILLMLLGGVHKITREGISLRGDINVCIVGDPSTAKSQFLKYVEEFSPRAVYTSGKASSAAGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 369 TAAVTSDQETGERRLEAGAMVLADKGIVCIDEFDKMNDQDRVAIHEVMEQQTVTIAKAGIHASLNARCSVVAAANPIYGT 448
Cdd:cd17757 82 TAAVVRDEETGDFVIEAGALMLADNGICCIDEFDKMDIKDQVAIHEAMEQQTISITKAGIQATLNARTSILAAANPVGGR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 449 YDRSLTPTKNIGLPDSLLSRFDLLFIVLDQMDAGIDSMISEHVLRMHRYKNDRGEAgpdgslPYAREDnaesemfvkynq 528
Cdd:cd17757 162 YDRSKSLKQNINISAPIMSRFDLFFVLLDECNEVTDYAIASHIVDLHSKREEAIEP------PFTAEQ------------ 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 529 tlhgkkkrgqthdktltikfLKKYIHYAKhRITPKLTDEASERIAEAYADLRNAGSDTKTGGTLPITARTLETIIRLATA 608
Cdd:cd17757 224 --------------------LKRYIAYAR-TFKPKLTKEAKDELVEQYKELRQDDASGSTRSSYRITVRQLESLIRLSEA 282
|
330 340
....*....|....*....|...
gi 15237411 609 HAKMKLSSEVTKADAEAALKLMN 631
Cdd:cd17757 283 IARLHCSDEVTPEHVEEAARLLK 305
|
|
| MCM7 |
cd17758 |
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in ... |
289-633 |
1.45e-119 |
|
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350664 [Multi-domain] Cd Length: 306 Bit Score: 362.11 E-value: 1.45e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 289 LARSLAPSIYGHAWIKKAVVLLMLGGVEKNlKNGTHLRGDINMMMVGDPSVAKSQLLRAIMNIAPLAISTTGRGSSGVGL 368
Cdd:cd17758 2 LAASIAPEIYGHEDVKKALLLLLVGGVDKR-GDGMKIRGDINICLMGDPGVAKSQLLKYICRIAPRSVYTTGRGSSGVGL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 369 TAAVTSDQETGERRLEAGAMVLADKGIVCIDEFDKMNDQDRVAIHEVMEQQTVTIAKAGIHASLNARCSVVAAANPIYGT 448
Cdd:cd17758 81 TAAVMKDPVTGEMTLEGGALVLADQGICCIDEFDKMDESDRTAIHEVMEQQTISIAKAGITTTLNARTSILAAANPAYGR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 449 YDRSLTPTKNIGLPDSLLSRFDLLFIVLDQMDAGIDSMISEHVLRMHrykndrgeagpdgslpyarednaesemfvkynq 528
Cdd:cd17758 161 YNPRRSPEQNINLPAALLSRFDLLFLILDKPDRDNDLRLAEHVTYVH--------------------------------- 207
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 529 tLHGKKKRGQThdKTLTIKFLKKYIHYAKhRITPKLTDEASERIAEAYADLRNAGSDTKTGGTlpITARTLETIIRLATA 608
Cdd:cd17758 208 -QHNKQPDSDF--EPLDPKLLRAYIALAK-RKRPTVPPALADYIVQAYVEMRQEAKRSKDFTF--TTPRTLLAILRLSQA 281
|
330 340
....*....|....*....|....*
gi 15237411 609 HAKMKLSSEVTKADAEAALKLMNFA 633
Cdd:cd17758 282 LARLRLSDSVEIDDVEEALRLMEMS 306
|
|
| MCM4 |
cd17755 |
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in ... |
288-633 |
2.08e-117 |
|
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350661 [Multi-domain] Cd Length: 309 Bit Score: 356.75 E-value: 2.08e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 288 LLARSLAPSIYGHAWIKKAVVLLMLGGVEKNL-KNGTHLRGDINMMMVGDPSVAKSQLLRAIMNIAPLAISTTGRGSSGV 366
Cdd:cd17755 1 RLARSIAPSIYELEDVKKGILLQLFGGTRKDFtKTGGKYRGDINILLCGDPGTSKSQLLQYVHKISPRGVYTSGKGSSAV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 367 GLTAAVTSDQETGERRLEAGAMVLADKGIVCIDEFDKMNDQDRVAIHEVMEQQTVTIAKAGIHASLNARCSVVAAANPIY 446
Cdd:cd17755 81 GLTAYVTRDPDTKQLVLESGALVLSDGGICCIDEFDKMSDSTRSVLHEVMEQQTLSIAKAGIITTLNARTSILASANPIG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 447 GTYDRSLTPTKNIGLPDSLLSRFDLLFIVLDQMDAGIDSMISEHVLRMHrYKNDRGEAGPDgslpyarednaesemfvky 526
Cdd:cd17755 161 SRYNPKLTVVENIDLPPTLLSRFDLIYLVLDKVDEKYDRRLAKHLVSLY-LEDTPEHIQDE------------------- 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 527 nqtlhgkkkrgqthdkTLTIKFLKKYIHYAKHRITPKLTDEASERIAEAYADLRNAGSDtkTGGTLPITARTLETIIRLA 606
Cdd:cd17755 221 ----------------VLDVEVLTDYISYAREHIHPKLSEEAAQELVQAYVDMRKMGSD--ARKRITATPRQLESLIRLA 282
|
330 340
....*....|....*....|....*..
gi 15237411 607 TAHAKMKLSSEVTKADAEAALKLMNFA 633
Cdd:cd17755 283 EAHAKMRLSNVVEAEDVEEAVRLIREA 309
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
103-636 |
9.58e-88 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 296.52 E-value: 9.58e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 103 TPRELLSDFIGSMVCVEGIVTKCSLVRPKVVKSVHFCPSTGEFTNRDYRDITSH------AGLPTGSVYPTRDDKGNLLV 176
Cdd:PTZ00111 217 CVGNLEPSMADSLVQFSGTVVRQTWIVPEITMACFRCRGQKKIGLNDYQPCTCEhyeyviQGEVNEPLLCNECNSKYTFE 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 177 TEYGLCKYKDHQTLSIQEVPENAAPGQLP--------------------RSVDVIAEDDLVDSCKPGDRVSVFGIYKALP 236
Cdd:PTZ00111 297 LNHNMCVYSTKKIVKLLQSNSSLNNPDKDgldnsvdnsglngeiymkdnEVINLNLYDDLIDSVKTGDRVTVVGILKVTP 376
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 237 ---GKSKGSVNGVFRTILIANNIALLNK-EANAPI-----------YTKQDLDNIKNIARRDDAFDLLARSLAPSIYGHA 301
Cdd:PTZ00111 377 irtSTTRRTLKSLYTYFVNVIHVKVINStNANQPEkglkylgnendFSDLQVYKILELSRNPMIYRILLDSFAPSIKARN 456
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 302 WIKKAVVLLMLGGVEKNLKNGT---------HLRGDINMMMVGDPSVAKSQLLRAIMNIAPLAISTTGRGSSGVGLTAAV 372
Cdd:PTZ00111 457 NVKIGLLCQLFSGNKNSSDFNKspdacykvdNFRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSVGLTASI 536
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 373 T-SDQETGERRLEAGAMVLADKGIVCIDEFDKMNDQDRVAIHEVMEQQTVTIAKAGIHASLNARCSVVAAANPIYGTYDR 451
Cdd:PTZ00111 537 KfNESDNGRAMIQPGAVVLANGGVCCIDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAILASCNPINSRYNK 616
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 452 SLTPTKNIGLPDSLLSRFDLLFIVLDQMDAGIDSMISEHVLRmhrykndrgeagpDGSLPYAREDNAESEMFVKYNqTLH 531
Cdd:PTZ00111 617 NKAVIENINISPSLFTRFDLIYLVLDHIDQDTDQLISLSIAK-------------DFLLPHMTGSGNDEDTYDRSN-TMH 682
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 532 GKKK--RGQTHDKTLTIKFLKKYIHYAKHRITPKLTDEASERIAEAYADLRNAGSDT--------------------KTG 589
Cdd:PTZ00111 683 VEDEslRSEKDYNKNDLDMLRMYIKFSKLHCFPKLSDEAKKVITREYVKMRQGNFQTsnldelehaqedddddlyyqSSG 762
|
570 580 590 600
....*....|....*....|....*....|....*....|....*...
gi 15237411 590 GTLP-ITARTLETIIRLATAHAKMKLSSEVTKADAEAALKLMNFAIYH 636
Cdd:PTZ00111 763 TRMIyVSSRMISSIIRISVSLARMRLSTVVTPADALQAVQIVKSSTFQ 810
|
|
| MCM8 |
cd17759 |
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a ... |
288-630 |
7.54e-80 |
|
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a complex with Mcm9 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350665 [Multi-domain] Cd Length: 289 Bit Score: 257.85 E-value: 7.54e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 288 LLARSLAPSIYGHAWIKKAVVLLMLGGVEK--NLKNGTHLRGDINMMMVGDPSVAKSQLLRAIMNIAPLAISTTGRGSSG 365
Cdd:cd17759 1 LIVNSLCPAIYGHELVKAGLLLSLFGGKQKyaDDKNRIPIRGDPHVLIVGDPGLGKSQMLQAACNIAPRGVYVCGNTTTT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 366 VGLTAAVTSDQETGERRLEAGAMVLADKGIVCIDEFDKMNDQDRvAIHEVMEQQTVTIAKAGIHASLNARCSVVAAANPI 445
Cdd:cd17759 81 SGLTVTLTKDGRSGDFALEAGALVLGDQGICGIDEFDKMGSQHQ-ALLEAMEQQSVSLAKAGVVCSLPARTSVIAAANPV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 446 YGTYDRSLTPTKNIGLPDSLLSRFDLLFIVLDQMDAGIDSMISEHvlrmhrykndrgeagpdgslpyarednaesemfvk 525
Cdd:cd17759 160 GGHYNKGKTVSENLKMGPALLSRFDLVFILLDTPSEEHDHLLSEH----------------------------------- 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 526 ynqtlhgkkkrgqtHDktltikFLKKYIHYAKHRITPKLTDEASERIAEAYADLRNAGsdtKTGGTLPITARTLETIIRL 605
Cdd:cd17759 205 --------------HQ------LLRKYISYARQYVNPVLSKDASEALQEFYLELRKQN---QLADSSPITTRQLESLIRL 261
|
330 340
....*....|....*....|....*
gi 15237411 606 ATAHAKMKLSSEVTKADAEAALKLM 630
Cdd:cd17759 262 TEARARLELREEATKEDAEDVIEIM 286
|
|
| MCM9 |
cd17760 |
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a ... |
288-630 |
1.07e-66 |
|
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a complex with Mcm8 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350666 [Multi-domain] Cd Length: 299 Bit Score: 223.19 E-value: 1.07e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 288 LLARSLAPSIYGHAWIKKAVVLLMLGGVEKNLKNGTHLRGDINMMMVGDPSVAKSQLLRAIMNIAPLAISTTGRGSSGVG 367
Cdd:cd17760 1 EILASLCPQVFGLYNVKLAVAMVLAGGVQRIDASGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTAGIGSTSAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 368 LTaaVTSDQETGERRLEAGAMVLADKGIVCIDEFDKMNDQDRVAIHEVMEQQTVTIAKAGIHASLNARCSVVAAANPiYG 447
Cdd:cd17760 81 LT--VTAVKDGGEWNLEAGALVLADGGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNP-KG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 448 TYDRSLTPTKNIGLPDSLLSRFDLLFIVLDQMDAGIDSMISEHVLRmhryknDRGEagPDGSlpyarednaesemfvkyn 527
Cdd:cd17760 158 QYDPNESISVNIALASPLLSRFDLVLVLLDTKNEDWDRIISSFILE------NKGE--PSKS------------------ 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 528 qtlhgkkkrgqthDKTLTIKFLKKYIHYAKhRITPKLTDEASERIAEAY-----ADLRNAGSDtktggtlpiTARTLETI 602
Cdd:cd17760 212 -------------SKLWSMEKMRTYFCLIK-NLRPVLSDEANAILLRYYqlqrqSDCRNAART---------TIRMLESL 268
|
330 340
....*....|....*....|....*...
gi 15237411 603 IRLATAHAKMKLSSEVTKADAEAALKLM 630
Cdd:cd17760 269 IRLAEAHARLMFRETVTEEDAITVVSVM 296
|
|
| MCM_OB |
pfam17207 |
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains ... |
105-236 |
3.50e-44 |
|
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains an insertion at the zinc binding motif.
Pssm-ID: 465381 [Multi-domain] Cd Length: 126 Bit Score: 154.95 E-value: 3.50e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 105 RELLSDFIGSMVCVEGIVTKCSLVRPKVVKSVHFCPSTGEFTNRDYRDITSHAGLPTGSVYPtrddkgNLLVTEygLCKY 184
Cdd:pfam17207 3 RDLRSEHIGKLVSVSGIVTRTSEVRPKLKKATFTCRKCGHTVGVKITEPTKCPNPECGNKDP------FKLVHE--KSKF 74
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 15237411 185 KDHQTLSIQEVPENAAPGQLPRSVDVIAEDDLVDSCKPGDRVSVFGIYKALP 236
Cdd:pfam17207 75 VDFQKIKIQESPEEVPAGELPRSLDVILDDDLVDRVKPGDRVTVTGIYRVVP 126
|
|
| MCM_lid |
pfam17855 |
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins. |
548-634 |
9.65e-32 |
|
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins.
Pssm-ID: 465534 [Multi-domain] Cd Length: 86 Bit Score: 118.41 E-value: 9.65e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 548 FLKKYIHYAKHRITPKLTDEASERIAEAYADLRNAGSDTktGGTLPITARTLETIIRLATAHAKMKLSSEVTKADAEAAL 627
Cdd:pfam17855 2 LLRKYIAYAREKIKPKLSEEAREKLVDAYVELRKESTGS--GSSIPITVRQLESLIRLSEAHAKMRLSEIVTEEDVEEAI 79
|
....*..
gi 15237411 628 KLMNFAI 634
Cdd:pfam17855 80 RLLKESL 86
|
|
| MCM_N |
pfam14551 |
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins. |
12-95 |
2.08e-11 |
|
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.
Pssm-ID: 464206 [Multi-domain] Cd Length: 95 Bit Score: 60.77 E-value: 2.08e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 12 KRDFIQFLDS---------MYMEEIKALVHQKRHRLIINISDIHHHFREVASRILKNPNEYMQSFCDAATEATRAI--DP 80
Cdd:pfam14551 1 KRKFKDFLEEfredgdgefKYRDQLREMIEREQRSLEVDLDDLREFDPDLAEALLENPYEYLPLFEEALKEVVKELseDP 80
|
90
....*....|....*
gi 15237411 81 KYLKEGELVLVGFEG 95
Cdd:pfam14551 81 DYAEEEKEFQVRFYN 95
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
330-469 |
2.92e-06 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 47.29 E-value: 2.92e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 330 NMMMVGDPSVAKSQLLRAimniapLAISTTGRGSSGVGLTAAVTSDQETGERRLEAGAMVLAD---------KGIVCIDE 400
Cdd:pfam07728 1 GVLLVGPPGTGKTELAER------LAAALSNRPVFYVQLTRDTTEEDLFGRRNIDPGGASWVDgplvraareGEIAVLDE 74
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15237411 401 FDKMNDQDRVAIHEVMEQQTVTIAKAG--IHASLNARcSVVAAANPIygtyDRSLTPtknigLPDSLLSRF 469
Cdd:pfam07728 75 INRANPDVLNSLLSLLDERRLLLPDGGelVKAAPDGF-RLIATMNPL----DRGLNE-----LSPALRSRF 135
|
|
| MoxR |
COG0714 |
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway ... |
335-477 |
1.09e-03 |
|
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 440478 [Multi-domain] Cd Length: 292 Bit Score: 41.69 E-value: 1.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 335 GDPSVAKSQLLRAI---MNIAPLAISTTgrgssgVGLTAA-VT----SDQETGERRLEAGAmVLAdkGIVCIDEFDKMND 406
Cdd:COG0714 38 GVPGVGKTTLAKALaraLGLPFIRIQFT------PDLLPSdILgtyiYDQQTGEFEFRPGP-LFA--NVLLADEINRAPP 108
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15237411 407 QDRVAIHEVMEQQTVTIAKAGIHASlnARCSVVAAANPI--YGTYDrsltptknigLPDSLLSRFdLLFIVLD 477
Cdd:COG0714 109 KTQSALLEAMEERQVTIPGGTYKLP--EPFLVIATQNPIeqEGTYP----------LPEAQLDRF-LLKLYIG 168
|
|
| Mg_chelatase |
pfam01078 |
Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that ... |
330-444 |
1.42e-03 |
|
Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that catalyzes the insertion of Mg2+ into protoporphyrin IX. This is the first unique step in the synthesis of (bacterio)chlorophyll. Due to this, it is thought that Mg-chelatase has an important role in channelling inter- mediates into the (bacterio)chlorophyll branch in response to conditions suitable for photosynthetic growth. ChlI and BchD have molecular weight between 38-42 kDa.
Pssm-ID: 426032 [Multi-domain] Cd Length: 207 Bit Score: 40.60 E-value: 1.42e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 330 NMMMVGDPSVAKSQLLRAIMNIAP----------LAI-STTGRG-----------------SSGVGLTAavtsdqetGER 381
Cdd:pfam01078 24 NLLMIGPPGSGKTMLAKRLPGILPplteaealevTAIhSVAGLGgdgglirrrpfraphhsASAAALVG--------GGS 95
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15237411 382 RLEAGAMVLADKGIVCIDE---FDKmndqdRV--AIHEVMEQQTVTIAKAGIHASLNARCSVVAAANP 444
Cdd:pfam01078 96 IPRPGEISLAHNGVLFLDElpeFKR-----RVleSLRQPLEDGEITISRARAKVTFPARFQLVAAMNP 158
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
330-475 |
3.21e-03 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 39.05 E-value: 3.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237411 330 NMMMVGDPSVAKSQLLRAIMNIAP------LAISTTGRGSSGVGLtaavtSDQETGERRLEAGAMVLADKGIVCIDEFDK 403
Cdd:cd00009 21 NLLLYGPPGTGKTTLARAIANELFrpgapfLYLNASDLLEGLVVA-----ELFGHFLVRLLFELAEKAKPGVLFIDEIDS 95
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15237411 404 MNDQDRVAIHEVMEQQTVTIAKagihaslNARCSVVAAANPIYgtydrsltptkNIGLPDSLLSRFDLLFIV 475
Cdd:cd00009 96 LSRGAQNALLRVLETLNDLRID-------RENVRVIGATNRPL-----------LGDLDRALYDRLDIRIVI 149
|
|
| |
