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Conserved domains on  [gi|30697397|ref|NP_200868|]
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4-hydroxy-3-methylbut-2-enyl diphosphate synthase [Arabidopsis thaliana]

Protein Classification

flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase( domain architecture ID 11477294)

flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate, part of an alternative non-mevalonate pathway for isoprenoid biosynthesis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLN02925 PLN02925
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase
 1-739 0e+00

4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase


:

Pssm-ID: 178513  Cd Length: 733  Bit Score: 1562.43  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397    1 MATGVLPAPVSGIKIPDSKVGFGKSMNLVRICDVRslrsarrRVSVIRNSNQGSDLAELQPASEGSPLLVPRQKYCESLH 80
Cdd:PLN02925   1 MATGVLPAPLSGLKTSDSKLGFGKSMDFVRICDVR-------SVSVIRNSNTGPDLVELQPASEGSPLLVPRQKYCESIH 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397   81 KTVRRKTRTVMVGNVALGSEHPIRIQTMTTSDTKDITGTVDEVMRIADKGADIVRITVQGKKEADACFEIKDKLVQLNYN 160
Cdd:PLN02925  74 KTVRRKTRTVMVGNVALGSEHPIRIQTMTTTDTKDVEATVDQVMRIADKGADIVRITVQGKKEADACFEIKNTLVQKGYN 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397  161 IPLVADIHFAPTVALRVAECFDKIRVNPGNFADRRAQFETIDYTEDEYQKELQHIEQVFTPLVEKCKKYGRAMRIGTNHG 240
Cdd:PLN02925 154 IPLVADIHFAPSVALRVAECFDKIRVNPGNFADRRAQFEKLEYTEDDYQKELEHIEEVFTPLVEKCKKYGRAMRIGTNHG 233

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397  241 SLSDRIMSYYGDSPRGMVESAFEFARICRKLDYHNFVFSMKASNPVIMVQAYRLLVAEMYVHGWDYPLHLGVTEAGEGED 320
Cdd:PLN02925 234 SLSDRIMSYYGDSPRGMVESAFEFARICRKLDYHNFVFSMKASNPVVMVQAYRLLVAEMYVLGWDYPLHLGVTEAGEGED 313

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397  321 GRMKSAIGIGTLLQDGLGDTIRVSLTEPPEEEIDPCRRLANLGTKAAKLQQG-APFEEKHRHYFDFQRRTGDLPVQKEGE 399
Cdd:PLN02925 314 GRMKSAIGIGTLLQDGLGDTIRVSLTEPPEEEIDPCRRLANLGMKAAALQQGvAPFEEKHRDYFDFQRRTGQLPVQKEGE 393

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397  400 EVDYRNVLHRDGSVLMSISLDQLKAPELLYRSLATKLVVGMPFKDLATVDSILLRELPPVDDQVARLALKRLIDVSMGVI 479
Cdd:PLN02925 394 EVDYRNVLHRDGSVLMSVSLDQLKAPELLYRSLAAKLVVGMPFKDLATVDSILLRELPPVDDEEARLALKRLIDVSMGVI 473

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397  480 APLSEQLTKPLPNAMVLVNLKELSGGAYKLLPEGTRLVVSLRGDEPYEELEILKNIDATMILHDVPFTEDKVSRVHAARR 559
Cdd:PLN02925 474 APLSEQLTKPLPNAMALVNLKELSSGAHKLLPEGTRLAVTLRGDEPYEELEILKDVDATMLLHDVPFTEDKVSRVHAARR 553

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397  560 LFEFLSENSVNFPVIHHINFPTGIHRDELVIHAGTYAGGLLVDGLGDGVMLEAPDQDFDFLRNTSFNLLQGCRMRNTKTE 639
Cdd:PLN02925 554 LFEYLSSNSLNFPVIHHIQFPAGIHRDDLVIQAGSQAGALLVDGLGDGVLLEAPDQDFDFLRNTSFGLLQGCRMRNTKTE 633

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397  640 YVSCPSCGRTLFDLQEISAEIREKTSHLPGVSIAIMGCIVNGPGEMADADFGYVGGSPGKIDLYVGKTVVKRGIAMTEAT 719
Cdd:PLN02925 634 YVSCPSCGRTLFDLQEVSAEIREKTSHLPGVSIAIMGCIVNGPGEMADADFGYVGGAPGKIDLYVGKEVVKRGIAMEEAT 713

                        730       740
                 ....*....|....*....|
gi 30697397  720 DALIGLIKEHGRWVDPPVAD 739
Cdd:PLN02925 714 DALIQLIKDHGRWVDPEVEE 733
 
Name Accession Description Interval E-value
PLN02925 PLN02925
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase
 1-739 0e+00

4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase


Pssm-ID: 178513  Cd Length: 733  Bit Score: 1562.43  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397    1 MATGVLPAPVSGIKIPDSKVGFGKSMNLVRICDVRslrsarrRVSVIRNSNQGSDLAELQPASEGSPLLVPRQKYCESLH 80
Cdd:PLN02925   1 MATGVLPAPLSGLKTSDSKLGFGKSMDFVRICDVR-------SVSVIRNSNTGPDLVELQPASEGSPLLVPRQKYCESIH 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397   81 KTVRRKTRTVMVGNVALGSEHPIRIQTMTTSDTKDITGTVDEVMRIADKGADIVRITVQGKKEADACFEIKDKLVQLNYN 160
Cdd:PLN02925  74 KTVRRKTRTVMVGNVALGSEHPIRIQTMTTTDTKDVEATVDQVMRIADKGADIVRITVQGKKEADACFEIKNTLVQKGYN 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397  161 IPLVADIHFAPTVALRVAECFDKIRVNPGNFADRRAQFETIDYTEDEYQKELQHIEQVFTPLVEKCKKYGRAMRIGTNHG 240
Cdd:PLN02925 154 IPLVADIHFAPSVALRVAECFDKIRVNPGNFADRRAQFEKLEYTEDDYQKELEHIEEVFTPLVEKCKKYGRAMRIGTNHG 233

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397  241 SLSDRIMSYYGDSPRGMVESAFEFARICRKLDYHNFVFSMKASNPVIMVQAYRLLVAEMYVHGWDYPLHLGVTEAGEGED 320
Cdd:PLN02925 234 SLSDRIMSYYGDSPRGMVESAFEFARICRKLDYHNFVFSMKASNPVVMVQAYRLLVAEMYVLGWDYPLHLGVTEAGEGED 313

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397  321 GRMKSAIGIGTLLQDGLGDTIRVSLTEPPEEEIDPCRRLANLGTKAAKLQQG-APFEEKHRHYFDFQRRTGDLPVQKEGE 399
Cdd:PLN02925 314 GRMKSAIGIGTLLQDGLGDTIRVSLTEPPEEEIDPCRRLANLGMKAAALQQGvAPFEEKHRDYFDFQRRTGQLPVQKEGE 393

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397  400 EVDYRNVLHRDGSVLMSISLDQLKAPELLYRSLATKLVVGMPFKDLATVDSILLRELPPVDDQVARLALKRLIDVSMGVI 479
Cdd:PLN02925 394 EVDYRNVLHRDGSVLMSVSLDQLKAPELLYRSLAAKLVVGMPFKDLATVDSILLRELPPVDDEEARLALKRLIDVSMGVI 473

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397  480 APLSEQLTKPLPNAMVLVNLKELSGGAYKLLPEGTRLVVSLRGDEPYEELEILKNIDATMILHDVPFTEDKVSRVHAARR 559
Cdd:PLN02925 474 APLSEQLTKPLPNAMALVNLKELSSGAHKLLPEGTRLAVTLRGDEPYEELEILKDVDATMLLHDVPFTEDKVSRVHAARR 553

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397  560 LFEFLSENSVNFPVIHHINFPTGIHRDELVIHAGTYAGGLLVDGLGDGVMLEAPDQDFDFLRNTSFNLLQGCRMRNTKTE 639
Cdd:PLN02925 554 LFEYLSSNSLNFPVIHHIQFPAGIHRDDLVIQAGSQAGALLVDGLGDGVLLEAPDQDFDFLRNTSFGLLQGCRMRNTKTE 633

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397  640 YVSCPSCGRTLFDLQEISAEIREKTSHLPGVSIAIMGCIVNGPGEMADADFGYVGGSPGKIDLYVGKTVVKRGIAMTEAT 719
Cdd:PLN02925 634 YVSCPSCGRTLFDLQEVSAEIREKTSHLPGVSIAIMGCIVNGPGEMADADFGYVGGAPGKIDLYVGKEVVKRGIAMEEAT 713

                        730       740
                 ....*....|....*....|
gi 30697397  720 DALIGLIKEHGRWVDPPVAD 739
Cdd:PLN02925 714 DALIQLIKDHGRWVDPEVEE 733
GcpE pfam04551
GcpE protein; In a variety of organizms, including plants and several eubacteria, isoprenoids ...
 87-359 6.55e-128

GcpE protein; In a variety of organizms, including plants and several eubacteria, isoprenoids are synthesized by the mevalonate-independent 2-C-methyl-D-erythritol 4-phosphate (MEP) pathway. Although different enzymes of this pathway have been described, the terminal biosynthetic steps of the MEP pathway have not been fully elucidated. GcpE gene of Escherichia coli is involved in this pathway.


Pssm-ID: 428003 [Multi-domain]  Cd Length: 343  Bit Score: 383.99  E-value: 6.55e-128
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397    87 TRTVMVGNVALGSEHPIRIQTMTTSDTKDITGTVDEVMRIADKGADIVRITVQGKKEADACFEIKDKLvqlnyNIPLVAD 166
Cdd:pfam04551   1 TRQVRVGNVPIGGGAPIVVQSMTNTDTRDVEATVAQIRRLAEAGCEIVRVAVPDMEAAEALKEIKKRL-----PIPLVAD 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397   167 IHFAPTVALRVAEC-FDKIRVNPGNFADRRAqfetidytedeyqkelqhieqvFTPLVEKCKKYGRAMRIGTNHGSLSDR 245
Cdd:pfam04551  76 IHFDYRLALEAAEAgVDKIRINPGNIGSEEK----------------------VREVVEAAKERGIPIRIGVNSGSLEKD 133

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397   246 IMSYYGD-SPRGMVESAFEFARICRKLDYHNFVFSMKASNPVIMVQAYRLLVAEMyvhgwDYPLHLGVTEAGEGEDGRMK 324
Cdd:pfam04551 134 LLEKYGGpTPEALVESALEHVRILEELGFDDIVISLKASDVPLTVEAYRLLAERC-----DYPLHLGVTEAGTGESGTIK 208

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 30697397   325 SAIGIGTLLQDGLGDTIRVSLTEPPEEEIDPCRRL 359
Cdd:pfam04551 209 SAVGIGALLAEGIGDTIRVSLTGDPVEEVKVAKEI 243
IspG COG0821
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE [Lipid transport and metabolism] ...
 84-353 7.14e-110

4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE [Lipid transport and metabolism]; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE is part of the Pathway/BioSystem: Isoprenoid biosynthesis


Pssm-ID: 440583 [Multi-domain]  Cd Length: 363  Bit Score: 338.17  E-value: 7.14e-110
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397  84 RRKTRTVMVGNVALGSEHPIRIQTMTTSDTKDITGTVDEVMRIADKGADIVRITVQGKKEADACFEIKDKLvqlnyNIPL 163
Cdd:COG0821   8 RRKTRQVRVGNVAIGGGAPISVQSMTNTDTADVEATVAQIKALAEAGCEIVRVAVPDEEAAAALPEIKKQL-----PVPL 82

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397 164 VADIHFAPTVALRVAECF-DKIRVNPGNFADRRAqfetidytedeyqkelqhieqvFTPLVEKCKKYGRAMRIGTNHGSL 242
Cdd:COG0821  83 VADIHFDYRLALEAAEAGvDKLRINPGNIGSDEK----------------------VREVVEAAKERGIPIRIGVNAGSL 140

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397 243 SDRIMSYYGD-SPRGMVESAFEFARICRKLDYHNFVFSMKASNPVIMVQAYRLLVAEMyvhgwDYPLHLGVTEAGEGEDG 321
Cdd:COG0821 141 EKDLLEKYGDpTPEALVESALEHARILEELGFDDIKISLKASDVQDTIAAYRLLAERC-----DYPLHLGVTEAGTGRKG 215

                       250       260       270
                ....*....|....*....|....*....|..
gi 30697397 322 RMKSAIGIGTLLQDGLGDTIRVSLTEPPEEEI 353
Cdd:COG0821 216 TVKSAAGLGILLAEGIGDTIRVSLTADPVEEV 247
ispG_gcpE TIGR00612
1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; This protein of previously unknown ...
 84-366 9.18e-105

1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; This protein of previously unknown biochemical function has now been identified as an enzyme of the non-mevalonate pathway of IPP biosynthesis. Chlamydial members of the family have a long insert. The family is largely restricted to Bacteria, where it is widely but not universally distributed. No homology can be detected between the GcpE family and other proteins. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]


Pssm-ID: 273174 [Multi-domain]  Cd Length: 346  Bit Score: 324.38  E-value: 9.18e-105
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397    84 RRKTRTVMVGNVALGSEHPIRIQTMTTSDTKDITGTVDEVMRIADKGADIVRITVQGKKEADACFEIKDKLvqlnyNIPL 163
Cdd:TIGR00612   1 RRKTRQVRVGNVKVGGDAPIVVQSMTNTDTHDVDATVAQIRRLEEAGCEIVRVTVPDKESAEALEEIKEGS-----NVPL 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397   164 VADIHFAPTVALR-VAECFDKIRVNPGNFADRRaqfetidytedeyqkelqhieqVFTPLVEKCKKYGRAMRIGTNHGSL 242
Cdd:TIGR00612  76 VADIHFAYSYAALaMAKGVAKVRINPGNIGFEE----------------------RVRDIVEKARRHGKAMRIGVNHGSL 133

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397   243 SDRIMSYYGD-SPRGMVESAFEFARICRKLDYHNFVFSMKASNPVIMVQAYRLLVAEMyvhgwDYPLHLGVTEAGEGEDG 321
Cdd:TIGR00612 134 ERRLLEKYGDpTAEAMVQSALEWAEILEKLGFRNVVVSMKASDVLQTVAAYRLLAERS-----DYPLHLGVTEAGMGVKG 208

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 30697397   322 RMKSAIGIGTLLQDGLGDTIRVSLTEPPEEEIDPCRR-LANLGTKA 366
Cdd:TIGR00612 209 IIKSSVGIGILLAMGIGDTIRVSLTDDPVVEVPVAYEiLQSLGLRR 254
 
Name Accession Description Interval E-value
PLN02925 PLN02925
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase
 1-739 0e+00

4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase


Pssm-ID: 178513  Cd Length: 733  Bit Score: 1562.43  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397    1 MATGVLPAPVSGIKIPDSKVGFGKSMNLVRICDVRslrsarrRVSVIRNSNQGSDLAELQPASEGSPLLVPRQKYCESLH 80
Cdd:PLN02925   1 MATGVLPAPLSGLKTSDSKLGFGKSMDFVRICDVR-------SVSVIRNSNTGPDLVELQPASEGSPLLVPRQKYCESIH 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397   81 KTVRRKTRTVMVGNVALGSEHPIRIQTMTTSDTKDITGTVDEVMRIADKGADIVRITVQGKKEADACFEIKDKLVQLNYN 160
Cdd:PLN02925  74 KTVRRKTRTVMVGNVALGSEHPIRIQTMTTTDTKDVEATVDQVMRIADKGADIVRITVQGKKEADACFEIKNTLVQKGYN 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397  161 IPLVADIHFAPTVALRVAECFDKIRVNPGNFADRRAQFETIDYTEDEYQKELQHIEQVFTPLVEKCKKYGRAMRIGTNHG 240
Cdd:PLN02925 154 IPLVADIHFAPSVALRVAECFDKIRVNPGNFADRRAQFEKLEYTEDDYQKELEHIEEVFTPLVEKCKKYGRAMRIGTNHG 233

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397  241 SLSDRIMSYYGDSPRGMVESAFEFARICRKLDYHNFVFSMKASNPVIMVQAYRLLVAEMYVHGWDYPLHLGVTEAGEGED 320
Cdd:PLN02925 234 SLSDRIMSYYGDSPRGMVESAFEFARICRKLDYHNFVFSMKASNPVVMVQAYRLLVAEMYVLGWDYPLHLGVTEAGEGED 313

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397  321 GRMKSAIGIGTLLQDGLGDTIRVSLTEPPEEEIDPCRRLANLGTKAAKLQQG-APFEEKHRHYFDFQRRTGDLPVQKEGE 399
Cdd:PLN02925 314 GRMKSAIGIGTLLQDGLGDTIRVSLTEPPEEEIDPCRRLANLGMKAAALQQGvAPFEEKHRDYFDFQRRTGQLPVQKEGE 393

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397  400 EVDYRNVLHRDGSVLMSISLDQLKAPELLYRSLATKLVVGMPFKDLATVDSILLRELPPVDDQVARLALKRLIDVSMGVI 479
Cdd:PLN02925 394 EVDYRNVLHRDGSVLMSVSLDQLKAPELLYRSLAAKLVVGMPFKDLATVDSILLRELPPVDDEEARLALKRLIDVSMGVI 473

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397  480 APLSEQLTKPLPNAMVLVNLKELSGGAYKLLPEGTRLVVSLRGDEPYEELEILKNIDATMILHDVPFTEDKVSRVHAARR 559
Cdd:PLN02925 474 APLSEQLTKPLPNAMALVNLKELSSGAHKLLPEGTRLAVTLRGDEPYEELEILKDVDATMLLHDVPFTEDKVSRVHAARR 553

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397  560 LFEFLSENSVNFPVIHHINFPTGIHRDELVIHAGTYAGGLLVDGLGDGVMLEAPDQDFDFLRNTSFNLLQGCRMRNTKTE 639
Cdd:PLN02925 554 LFEYLSSNSLNFPVIHHIQFPAGIHRDDLVIQAGSQAGALLVDGLGDGVLLEAPDQDFDFLRNTSFGLLQGCRMRNTKTE 633

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397  640 YVSCPSCGRTLFDLQEISAEIREKTSHLPGVSIAIMGCIVNGPGEMADADFGYVGGSPGKIDLYVGKTVVKRGIAMTEAT 719
Cdd:PLN02925 634 YVSCPSCGRTLFDLQEVSAEIREKTSHLPGVSIAIMGCIVNGPGEMADADFGYVGGAPGKIDLYVGKEVVKRGIAMEEAT 713

                        730       740
                 ....*....|....*....|
gi 30697397  720 DALIGLIKEHGRWVDPPVAD 739
Cdd:PLN02925 714 DALIQLIKDHGRWVDPEVEE 733
PRK00694 PRK00694
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated
 78-735 0e+00

4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated


Pssm-ID: 234812  Cd Length: 606  Bit Score: 581.41  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397   78 SLHKTVRRKTRTVMVGNVALGSEHPIRIQTMTTSDTKDITGTVDEVMRIADKGADIVRITVQGKKEADACFEIKDKLVQL 157
Cdd:PRK00694   6 CIQNAFRRKTHPVRIGNLFVGSEHSIKIQSMTTTATTDVDGTVRQICALQEWGCDIVRVTVQGLKEAQACEHIKERLIQQ 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397  158 NYNIPLVADIHFAPTVALRVAECFDKIRVNPGNFADRRAQFETIDYTEDEYQKELQHIEQVFTPLVEKCKKYGRAMRIGT 237
Cdd:PRK00694  86 GISIPLVADIHFFPQAAMHVADFVDKVRINPGNYVDKRNMFTGKIYTDEQYAHSLLRLEEKFSPLVEKCKRLGKAMRIGV 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397  238 NHGSLSDRIMSYYGDSPRGMVESAFEFARICRKLDYHNFVFSMKASNPVIMVQAYRLLVAEMYVHGWDYPLHLGVTEAGE 317
Cdd:PRK00694 166 NHGSLSERVMQRYGDTIEGMVYSALEYIEVCEKLDYRDVVFSMKSSNPKVMVAAYRQLAKDLDARGWLYPLHLGVTEAGS 245

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397  318 GEDGRMKSAIGIGTLLQDGLGDTIRVSLTEPPEEEIDPCRRLANLGTKAAKL-QQGAPFEEKHRHYFDFQrrtgdlpVQK 396
Cdd:PRK00694 246 GTDGIIKSAVGIGTLLSEGLGDTIRCSLTGCPTNEIPVCISLLKHTTEYLELpEKDNPFALHHSEQFVSA-------TRK 318

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397  397 EGEEVDYRNVLhrdgSVLMSISLDQL--KAPELLYRSLATKLVVGMpfKDLATVDsillrelppvddqvarlalkrlidv 474
Cdd:PRK00694 319 TLKTTPWGNVY----GVFIKLTDVHLltAEPEELLECLGIDPTTGK--KDFTTPE------------------------- 367

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397  475 smGVIAPlseqltKPLPNAMVLVNLKElsggaykllpegtRLVVSLRGDEP--YEELEILKNIDATmilHDVPFTEDKVS 552
Cdd:PRK00694 368 --GVVVP------KAMRSSPIVSELEK-------------HLLVFHHHDVPclYEMNEEIWLSEEV---LSAPFVHFHAT 423

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397  553 --RVHAARRLFEFLSENSVnfPVihHINFPTGIH-RDELVIHAGTYAGGLLVDGLGDGVMLEAPDQDFDFLRNTSFNLLQ 629
Cdd:PRK00694 424 dpFIHTARRFFSKRQHSTQ--PV--KLVFSLDPDsKNEAAIDIATEFGALLLDGLGECVLLDLPNIKLSDVRTIAFGTLQ 499

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397  630 GCRMRNTKTEYVSCPSCGRTLFDLQEISAEIREKTSHLPGVSIAIMGCIVNGPGEMADADFGYVGGSPGKIDLYVGKTVV 709
Cdd:PRK00694 500 SAGVRLVKTEYISCPGCGRTLFDLLEVTQRIRERTQHLPGLKIAVMGCIVNGPGEMADADFGFVGSKTGMIDLYVKHTCV 579

                        650       660
                 ....*....|....*....|....*.
gi 30697397  710 KRGIAMTEATDALIGLIKEHGRWVDP 735
Cdd:PRK00694 580 KAHIPMENAEEELVQLLKEHGVWKDP 605
PRK02048 PRK02048
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Provisional
 84-733 0e+00

4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Provisional


Pssm-ID: 179361  Cd Length: 611  Bit Score: 539.80  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397   84 RRKTRTVMVGNVALGSEHPIRIQTMTTSDTKDITGTVDEVMRIADKGADIVRITVQGKKEADACFEIKDKLVQLNYNIPL 163
Cdd:PRK02048   8 RRKTSVVNIGATPLGGPNPIRIQSMTNTSTMDTEACVAQAKRIIDAGGEYVRLTTQGVREAENLMNINIGLRSQGYMVPL 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397  164 VADIHFAPTVALRVAECFDKIRVNPGNFADRRAQFETIDYTEDEYQKELQHIEQVFTPLVEKCKKYGRAMRIGTNHGSLS 243
Cdd:PRK02048  88 VADVHFNPKVADVAAQYAEKVRINPGNYVDPGRTFKKLEYTDEEYAQEIQKIRDRFVPFLNICKENHTAIRIGVNHGSLS 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397  244 DRIMSYYGDSPRGMVESAFEFARICRKLDYHNFVFSMKASNPVIMVQAYRLLVAEMYVHGWDYPLHLGVTEAGEGEDGRM 323
Cdd:PRK02048 168 DRIMSRYGDTPEGMVESCMEFLRICVEEHFTDVVISIKASNTVVMVRTVRLLVAVMEAEGMHYPLHLGVTEAGDGEDGRI 247

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397  324 KSAIGIGTLLQDGLGDTIRVSLTEPPEEEIDPCRRLANLGTKaaklqqgapfEEKHRHyfdfqrrtgdLPVqKEGEEVDY 403
Cdd:PRK02048 248 KSAVGIGALLADGIGDTIRVSLSEEPEAEIPVARKLVDYIRS----------RENHPY----------IPG-MEAPGFDY 306

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397  404 RNVLHRDGSVLMSISLDQLKApellyrSLATKLVVGMPFKDLATVDSILL-RELPP-VDDQVARLALKRLIDVSMGVIap 481
Cdd:PRK02048 307 LSPSRRKTRAVRNIGGDHLPV------VIADRMDGDFEFDPQFLPDYIYAgRELPEqREPGVQYILDADVWKEEPNTW-- 378

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397  482 lseqltkPLPNAMVLVNLKELSgGAYKLLpegtrlvvSLRGDEPYEE-LEILKNIDATMILhdvpFTEDKVSRVHAARRL 560
Cdd:PRK02048 379 -------PAFNYAQLELMETCA-AELKFL--------FLPYMALTDEvLACLKAHPEVVVI----LQSNHPNRVGEHRAL 438

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397  561 FEFLSENSVNFPVIHHINFPTGiHRDELVIHAGTYAGGLLVDGLGDGVML----EAPDQDFDflrNTSFNLLQGCRMRNT 636
Cdd:PRK02048 439 AHQLMVAGLENPVIFFQHYAET-TAEDLQLKAAADMGALIFDGLCDGIFLfnqgKLSHVVVD---ATAFGILQAGRLRTS 514

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397  637 KTEYVSCPSCGRTLFDLQEISAEIREKTSHLPGVSIAIMGCIVNGPGEMADADFGYVGGSPGKIDLYVGKTVVKRGIAMT 716
Cdd:PRK02048 515 KTEYISCPGCGRTLYDLQSTIARIKEATSHLKGLKIGIMGCIVNGPGEMADADYGYVGAGRGKISLYKQKECVEKNIPEE 594

                        650
                 ....*....|....*..
gi 30697397  717 EATDALIGLIKEHGRWV 733
Cdd:PRK02048 595 EAVERLIELIKANGDWE 611
GcpE pfam04551
GcpE protein; In a variety of organizms, including plants and several eubacteria, isoprenoids ...
 87-359 6.55e-128

GcpE protein; In a variety of organizms, including plants and several eubacteria, isoprenoids are synthesized by the mevalonate-independent 2-C-methyl-D-erythritol 4-phosphate (MEP) pathway. Although different enzymes of this pathway have been described, the terminal biosynthetic steps of the MEP pathway have not been fully elucidated. GcpE gene of Escherichia coli is involved in this pathway.


Pssm-ID: 428003 [Multi-domain]  Cd Length: 343  Bit Score: 383.99  E-value: 6.55e-128
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397    87 TRTVMVGNVALGSEHPIRIQTMTTSDTKDITGTVDEVMRIADKGADIVRITVQGKKEADACFEIKDKLvqlnyNIPLVAD 166
Cdd:pfam04551   1 TRQVRVGNVPIGGGAPIVVQSMTNTDTRDVEATVAQIRRLAEAGCEIVRVAVPDMEAAEALKEIKKRL-----PIPLVAD 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397   167 IHFAPTVALRVAEC-FDKIRVNPGNFADRRAqfetidytedeyqkelqhieqvFTPLVEKCKKYGRAMRIGTNHGSLSDR 245
Cdd:pfam04551  76 IHFDYRLALEAAEAgVDKIRINPGNIGSEEK----------------------VREVVEAAKERGIPIRIGVNSGSLEKD 133

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397   246 IMSYYGD-SPRGMVESAFEFARICRKLDYHNFVFSMKASNPVIMVQAYRLLVAEMyvhgwDYPLHLGVTEAGEGEDGRMK 324
Cdd:pfam04551 134 LLEKYGGpTPEALVESALEHVRILEELGFDDIVISLKASDVPLTVEAYRLLAERC-----DYPLHLGVTEAGTGESGTIK 208

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 30697397   325 SAIGIGTLLQDGLGDTIRVSLTEPPEEEIDPCRRL 359
Cdd:pfam04551 209 SAVGIGALLAEGIGDTIRVSLTGDPVEEVKVAKEI 243
IspG COG0821
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE [Lipid transport and metabolism] ...
 84-353 7.14e-110

4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE [Lipid transport and metabolism]; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE is part of the Pathway/BioSystem: Isoprenoid biosynthesis


Pssm-ID: 440583 [Multi-domain]  Cd Length: 363  Bit Score: 338.17  E-value: 7.14e-110
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397  84 RRKTRTVMVGNVALGSEHPIRIQTMTTSDTKDITGTVDEVMRIADKGADIVRITVQGKKEADACFEIKDKLvqlnyNIPL 163
Cdd:COG0821   8 RRKTRQVRVGNVAIGGGAPISVQSMTNTDTADVEATVAQIKALAEAGCEIVRVAVPDEEAAAALPEIKKQL-----PVPL 82

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397 164 VADIHFAPTVALRVAECF-DKIRVNPGNFADRRAqfetidytedeyqkelqhieqvFTPLVEKCKKYGRAMRIGTNHGSL 242
Cdd:COG0821  83 VADIHFDYRLALEAAEAGvDKLRINPGNIGSDEK----------------------VREVVEAAKERGIPIRIGVNAGSL 140

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397 243 SDRIMSYYGD-SPRGMVESAFEFARICRKLDYHNFVFSMKASNPVIMVQAYRLLVAEMyvhgwDYPLHLGVTEAGEGEDG 321
Cdd:COG0821 141 EKDLLEKYGDpTPEALVESALEHARILEELGFDDIKISLKASDVQDTIAAYRLLAERC-----DYPLHLGVTEAGTGRKG 215

                       250       260       270
                ....*....|....*....|....*....|..
gi 30697397 322 RMKSAIGIGTLLQDGLGDTIRVSLTEPPEEEI 353
Cdd:COG0821 216 TVKSAAGLGILLAEGIGDTIRVSLTADPVEEV 247
ispG PRK00366
flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase;
84-353 8.48e-108

flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase;


Pssm-ID: 234737 [Multi-domain]  Cd Length: 360  Bit Score: 332.42  E-value: 8.48e-108
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397   84 RRKTRTVMVGNVALGSEHPIRIQTMTTSDTKDITGTVDEVMRIADKGADIVRITVQGKKEADACFEIKDKLvqlnyNIPL 163
Cdd:PRK00366   9 RRKTRQVKVGNVPIGGDAPIVVQSMTNTDTADVEATVAQIKRLARAGCEIVRVAVPDMEAAAALPEIKKQL-----PVPL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397  164 VADIHFAPTVALRVAE-CFDKIRVNPGNFADRRAQFETIdytedeyqkelqhieqvftplVEKCKKYGRAMRIGTNHGSL 242
Cdd:PRK00366  84 VADIHFDYRLALAAAEaGADALRINPGNIGKRDERVREV---------------------VEAAKDYGIPIRIGVNAGSL 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397  243 SDRIMSYYGD-SPRGMVESAFEFARICRKLDYHNFVFSMKASNPVIMVQAYRLLVAEMyvhgwDYPLHLGVTEAGEGEDG 321
Cdd:PRK00366 143 EKDLLEKYGEpTPEALVESALRHAKILEELGFDDIKISVKASDVQDLIAAYRLLAKRC-----DYPLHLGVTEAGMGFKG 217

                        250       260       270
                 ....*....|....*....|....*....|..
gi 30697397  322 RMKSAIGIGTLLQDGLGDTIRVSLTEPPEEEI 353
Cdd:PRK00366 218 TVKSAAGLGALLQEGIGDTIRVSLTADPVEEV 249
ispG_gcpE TIGR00612
1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; This protein of previously unknown ...
 84-366 9.18e-105

1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; This protein of previously unknown biochemical function has now been identified as an enzyme of the non-mevalonate pathway of IPP biosynthesis. Chlamydial members of the family have a long insert. The family is largely restricted to Bacteria, where it is widely but not universally distributed. No homology can be detected between the GcpE family and other proteins. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]


Pssm-ID: 273174 [Multi-domain]  Cd Length: 346  Bit Score: 324.38  E-value: 9.18e-105
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397    84 RRKTRTVMVGNVALGSEHPIRIQTMTTSDTKDITGTVDEVMRIADKGADIVRITVQGKKEADACFEIKDKLvqlnyNIPL 163
Cdd:TIGR00612   1 RRKTRQVRVGNVKVGGDAPIVVQSMTNTDTHDVDATVAQIRRLEEAGCEIVRVTVPDKESAEALEEIKEGS-----NVPL 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397   164 VADIHFAPTVALR-VAECFDKIRVNPGNFADRRaqfetidytedeyqkelqhieqVFTPLVEKCKKYGRAMRIGTNHGSL 242
Cdd:TIGR00612  76 VADIHFAYSYAALaMAKGVAKVRINPGNIGFEE----------------------RVRDIVEKARRHGKAMRIGVNHGSL 133

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397   243 SDRIMSYYGD-SPRGMVESAFEFARICRKLDYHNFVFSMKASNPVIMVQAYRLLVAEMyvhgwDYPLHLGVTEAGEGEDG 321
Cdd:TIGR00612 134 ERRLLEKYGDpTAEAMVQSALEWAEILEKLGFRNVVVSMKASDVLQTVAAYRLLAERS-----DYPLHLGVTEAGMGVKG 208

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 30697397   322 RMKSAIGIGTLLQDGLGDTIRVSLTEPPEEEIDPCRR-LANLGTKA 366
Cdd:TIGR00612 209 IIKSSVGIGILLAMGIGDTIRVSLTDDPVVEVPVAYEiLQSLGLRR 254
GcpE pfam04551
GcpE protein; In a variety of organizms, including plants and several eubacteria, isoprenoids ...
 597-728 3.86e-38

GcpE protein; In a variety of organizms, including plants and several eubacteria, isoprenoids are synthesized by the mevalonate-independent 2-C-methyl-D-erythritol 4-phosphate (MEP) pathway. Although different enzymes of this pathway have been described, the terminal biosynthetic steps of the MEP pathway have not been fully elucidated. GcpE gene of Escherichia coli is involved in this pathway.


Pssm-ID: 428003 [Multi-domain]  Cd Length: 343  Bit Score: 145.17  E-value: 3.86e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397   597 GGLLVDGLGDG--VML-EAPDQDFDflrnTSFNLLQGCRMRNTKTEYVSCPSCGRTLFDLQEISAEIREKTSHLP-GVSI 672
Cdd:pfam04551 214 GALLAEGIGDTirVSLtGDPVEEVK----VAKEILQSLGLRKRGVEIISCPTCGRTEIDLIELAEEVEERLEHLKkPLKV 289

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 30697397   673 AIMGCIVNGPGEMADADFGYVGGSpGKIDLYVGKTVVkRGIAMTEATDALIGLIKE 728
Cdd:pfam04551 290 AVMGCVVNGPGEAKEADIGIAGGK-GEGLLFKKGEIV-RKVPEEELVEELLEEIEK 343
ispG_gcpE TIGR00612
1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; This protein of previously unknown ...
 597-727 3.49e-34

1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; This protein of previously unknown biochemical function has now been identified as an enzyme of the non-mevalonate pathway of IPP biosynthesis. Chlamydial members of the family have a long insert. The family is largely restricted to Bacteria, where it is widely but not universally distributed. No homology can be detected between the GcpE family and other proteins. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]


Pssm-ID: 273174 [Multi-domain]  Cd Length: 346  Bit Score: 134.09  E-value: 3.49e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397   597 GGLLVDGLGDGV---MLEAPDQDFDflrnTSFNLLQGCRMRNTKTEYVSCPSCGRTLFDLQEISAEIREKTSHLPG-VSI 672
Cdd:TIGR00612 217 GILLAMGIGDTIrvsLTDDPVVEVP----VAYEILQSLGLRRRGVEIVACPSCGRTGFDLEKVVKEVQEALSHLKTpLKV 292

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 30697397   673 AIMGCIVNGPGEMADADFGYVGGSPGKIDLYVGKTvVKRGIAMTEATDALIGLIK 727
Cdd:TIGR00612 293 AVMGCVVNGPGEAKHADIGISGPGTGFAWLFKHGK-PKAKVPETDMVDELIKLIQ 346
IspG COG0821
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE [Lipid transport and metabolism] ...
 625-728 4.42e-24

4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE [Lipid transport and metabolism]; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE is part of the Pathway/BioSystem: Isoprenoid biosynthesis


Pssm-ID: 440583 [Multi-domain]  Cd Length: 363  Bit Score: 104.74  E-value: 4.42e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397 625 FNLLQGCRMRNTKTEYVSCPSCGRTLFDLQEISAEIREKTSHLP-GVSIAIMGCIVNGPGEMADADFGYVGGsPGKIDLY 703
Cdd:COG0821 251 QEILKSLGLRSRGPEVISCPTCGRTEIDLIQLAEEVEERLRDIKePLKVAVMGCVVNGPGEAKEADIGIAGG-GGEGLLF 329

                        90       100
                ....*....|....*....|....*.
gi 30697397 704 V-GKTVVKrgIAMTEATDALIGLIKE 728
Cdd:COG0821 330 KkGEIIRK--VPEDEIVEELLEEIEK 353
ispG PRK00366
flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase;
625-710 2.54e-23

flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase;


Pssm-ID: 234737 [Multi-domain]  Cd Length: 360  Bit Score: 102.07  E-value: 2.54e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30697397  625 FNLLQGCRMRNTKTEYVSCPSCGRTLFDLQEISAEIREKTSHLPG-VSIAIMGCIVNGPGEMADADFGYVGGSPgKIDLY 703
Cdd:PRK00366 253 QEILQSLGLRSRGPEVISCPTCGRTEFDVIQELAEVEQRLEHIKMpLKVAVMGCVVNGPGEAKEADIGIAGGNP-KGPVF 331


                 ....*...
gi 30697397  704 V-GKTVVK 710
Cdd:PRK00366 332 VdGEKIKT 339
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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