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Conserved domains on  [gi|15607257|ref|NP_214629|]
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D-alpha-D-heptose-7-phosphate kinase HddA [Mycobacterium tuberculosis H37Rv]

Protein Classification

COG2605 family protein( domain architecture ID 11457575)

COG2605 family protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG2605 COG2605
Predicted kinase related to galactokinase and mevalonate kinase [General function prediction ...
 4-342 1.20e-130

Predicted kinase related to galactokinase and mevalonate kinase [General function prediction only];


:

Pssm-ID: 442017 [Multi-domain]  Cd Length: 328  Bit Score: 377.60  E-value: 1.20e-130
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15607257   4 LRGRAPLRLGLGGGGTDVEPYSSQFGGRILSVTIDKYAYAFAERGTGDEIAFRSPDRDRAgqasiddlASLEEDFPLHVA 83
Cdd:COG2605   1 IISRAPLRISFAGGGTDLPPYYLEHGGAVLNAAIDKYAYVTLEPRFDGKIRLSSSDTERV--------ETVDEDDDIPHP 72

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15607257  84 VYRRVIAEFNGGTPFplQLATQVDAPPGSGLGSSSALVVAMLLTTCALIGSSPGPYELARLAWEIERVDLGMAGGWQDHY 163
Cdd:COG2605  73 VIREALKLFGIGDGL--EITTDSDAPAGSGLGSSSALTVALLNALHALLGLPLSPYDLARLAYEIERNDLGEPGGKQDQY 150

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15607257 164 AAAFGGFNFMESRPNGEVVVNPLRIRREVIAELEASLLLYFGGVSRLSSEVIADQQRNVVERDADALAATHSICAEALEM 243
Cdd:COG2605 151 AAAFGGFNFIEFGPDGRVIVNPLRISPEILNELESNLLLFYTGITRESSDILKEQVKNVEDGDEATLEALHEMKELALEM 230

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15607257 244 KDLLVVGDIPGFADSLLRGWQAKKRTSTRISNPAIEHAYQVAQSSGMVAGKVSGAGGGGFLMMIVDPRRRIEVARSLERE 323
Cdd:COG2605 231 KEALLKGDLDEFGELLNEGWELKKRLASGISNPAIDEIYELARKAGALGGKLLGAGGGGFLLFYAPPERREAVREALSKA 310

                       330
                ....*....|....*....
gi 15607257 324 cGGSVAPCLFTKGGAVTWH 342
Cdd:COG2605 311 -GLRVVPFSFDKEGSQVWR 328
 
Name Accession Description Interval E-value
COG2605 COG2605
Predicted kinase related to galactokinase and mevalonate kinase [General function prediction ...
 4-342 1.20e-130

Predicted kinase related to galactokinase and mevalonate kinase [General function prediction only];


Pssm-ID: 442017 [Multi-domain]  Cd Length: 328  Bit Score: 377.60  E-value: 1.20e-130
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15607257   4 LRGRAPLRLGLGGGGTDVEPYSSQFGGRILSVTIDKYAYAFAERGTGDEIAFRSPDRDRAgqasiddlASLEEDFPLHVA 83
Cdd:COG2605   1 IISRAPLRISFAGGGTDLPPYYLEHGGAVLNAAIDKYAYVTLEPRFDGKIRLSSSDTERV--------ETVDEDDDIPHP 72

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15607257  84 VYRRVIAEFNGGTPFplQLATQVDAPPGSGLGSSSALVVAMLLTTCALIGSSPGPYELARLAWEIERVDLGMAGGWQDHY 163
Cdd:COG2605  73 VIREALKLFGIGDGL--EITTDSDAPAGSGLGSSSALTVALLNALHALLGLPLSPYDLARLAYEIERNDLGEPGGKQDQY 150

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15607257 164 AAAFGGFNFMESRPNGEVVVNPLRIRREVIAELEASLLLYFGGVSRLSSEVIADQQRNVVERDADALAATHSICAEALEM 243
Cdd:COG2605 151 AAAFGGFNFIEFGPDGRVIVNPLRISPEILNELESNLLLFYTGITRESSDILKEQVKNVEDGDEATLEALHEMKELALEM 230

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15607257 244 KDLLVVGDIPGFADSLLRGWQAKKRTSTRISNPAIEHAYQVAQSSGMVAGKVSGAGGGGFLMMIVDPRRRIEVARSLERE 323
Cdd:COG2605 231 KEALLKGDLDEFGELLNEGWELKKRLASGISNPAIDEIYELARKAGALGGKLLGAGGGGFLLFYAPPERREAVREALSKA 310

                       330
                ....*....|....*....
gi 15607257 324 cGGSVAPCLFTKGGAVTWH 342
Cdd:COG2605 311 -GLRVVPFSFDKEGSQVWR 328
fkp PRK13412
bifunctional fucokinase/L-fucose-1-P-guanylyltransferase; Provisional
 72-320 2.60e-11

bifunctional fucokinase/L-fucose-1-P-guanylyltransferase; Provisional


Pssm-ID: 237379 [Multi-domain]  Cd Length: 974  Bit Score: 65.24  E-value: 2.60e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15607257   72 ASLEEdfplhvavyrrVIAEFNGGtpfpLQLATQVDAPPGSGLGSSSALVVAMLLTTCALIGSSPGPYELARLAWEIERV 151
Cdd:PRK13412 714 ASLEE-----------QLKAFGSG----IEITLLAAIPAGSGLGTSSILAATVLGAISDFCGLAWDKNEICNRTLVLEQL 778

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15607257  152 dLGMAGGWQDHYAAAFGGFNFMESRP--NGEVVVNPLRIRREVIAELEASLLLYFGGVSRLSSEVIADQQRNVVERDADA 229
Cdd:PRK13412 779 -LTTGGGWQDQYGGVLPGVKLLQTGAgfAQSPLVRWLPDSLFTQPEYRDCHLLYYTGITRTAKGILAEIVRSMFLNSTAH 857

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15607257  230 LAATHSICAEALEMKDLLVVGDIPGFADSLLRGWQAKKRTSTRISNPAIEHAYQVAQSSGMVAgKVSGAGGGGFLMMIV- 308
Cdd:PRK13412 858 LQLLHEMKAHALDMYEAIQRGEFEEFGRLVGKTWEQNKALDSGTNPAAVEAIIELIKDYTLGY-KLPGAGGGGYLYMVAk 936

                        250
                 ....*....|..
gi 15607257  309 DPRRRIEVARSL 320
Cdd:PRK13412 937 DPGAAERIRKIL 948
GHMP_kinases_N pfam00288
GHMP kinases N terminal domain; This family includes homoserine kinases, galactokinases and ...
 107-169 1.69e-10

GHMP kinases N terminal domain; This family includes homoserine kinases, galactokinases and mevalonate kinases.


Pssm-ID: 395225 [Multi-domain]  Cd Length: 64  Bit Score: 56.40  E-value: 1.69e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15607257   107 DAPPGSGLGSSSALVVAMLLTTCALIGSspgpyELARLAWEIERVDLGMAGGWQDHYAAAFGG 169
Cdd:pfam00288   7 NIPLGAGLGSSAALAVALLLALNELFGL-----PLAKLALEAEELAGGGRGGGMDVAASLYGG 64
mevalon_kin TIGR00549
mevalonate kinase; This model represents mevalonate kinase, the third step in the mevalonate ...
 81-296 4.65e-08

mevalonate kinase; This model represents mevalonate kinase, the third step in the mevalonate pathway of isopentanyl pyrophosphate (IPP) biosynthesis. IPP is a common intermediate for a number of pathways including cholesterol biosynthesis. This model covers enzymes from eukaryotes, archaea and bacteria. The related enzyme from the same pathway, phosphmevalonate kinase, serves as an outgroup for this clade. Paracoccus exhibits two genes within the phosphomevalonate/mevalonate kinase family, one of which falls between trusted and noise cutoffs of this model. The degree of divergence is high, but if the trees created from this model are correct, the proper names of these genes have been swapped. [Central intermediary metabolism, Other]


Pssm-ID: 273130 [Multi-domain]  Cd Length: 273  Bit Score: 53.83  E-value: 4.65e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15607257    81 HVAVYRRVIAEFNGGTPFPLQLATQVDAPPGSGLGSSSALVVAMLLTTCALIGSSPGPYELARLAWEIERVDLGMAGGwQ 160
Cdd:TIGR00549  60 LKYVLAEFLSRFSELNPPPLEITIESEIPPGRGLGSSAAVAVALIRALADYFGSELSKEELAELANEAEKIAHGKPSG-I 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15607257   161 DHYAAAFGGFNFMESRPNgevvvnplriRREVIAELEASLLLYFGGVSRLSSEVIADqQRNVVERDADALAATHSICAE- 239
Cdd:TIGR00549 139 DTATSTSGGPVYFEKGEG----------EFTKLISLDGYFVIADTGVSGSTKEAVAR-VRQLLERFPELIDSIMDAIGEl 207

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15607257   240 ------ALEMKDLLVVGDIPGFADSLLRgwqakkrtSTRISNPAIEHAYQVAQSSGMVAGKVS 296
Cdd:TIGR00549 208 tleakaALQDGDVESLGELMNINQGLLK--------ALGVSHPKLDQLVEIARKAGALGAKLT 262
 
Name Accession Description Interval E-value
COG2605 COG2605
Predicted kinase related to galactokinase and mevalonate kinase [General function prediction ...
 4-342 1.20e-130

Predicted kinase related to galactokinase and mevalonate kinase [General function prediction only];


Pssm-ID: 442017 [Multi-domain]  Cd Length: 328  Bit Score: 377.60  E-value: 1.20e-130
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15607257   4 LRGRAPLRLGLGGGGTDVEPYSSQFGGRILSVTIDKYAYAFAERGTGDEIAFRSPDRDRAgqasiddlASLEEDFPLHVA 83
Cdd:COG2605   1 IISRAPLRISFAGGGTDLPPYYLEHGGAVLNAAIDKYAYVTLEPRFDGKIRLSSSDTERV--------ETVDEDDDIPHP 72

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15607257  84 VYRRVIAEFNGGTPFplQLATQVDAPPGSGLGSSSALVVAMLLTTCALIGSSPGPYELARLAWEIERVDLGMAGGWQDHY 163
Cdd:COG2605  73 VIREALKLFGIGDGL--EITTDSDAPAGSGLGSSSALTVALLNALHALLGLPLSPYDLARLAYEIERNDLGEPGGKQDQY 150

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15607257 164 AAAFGGFNFMESRPNGEVVVNPLRIRREVIAELEASLLLYFGGVSRLSSEVIADQQRNVVERDADALAATHSICAEALEM 243
Cdd:COG2605 151 AAAFGGFNFIEFGPDGRVIVNPLRISPEILNELESNLLLFYTGITRESSDILKEQVKNVEDGDEATLEALHEMKELALEM 230

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15607257 244 KDLLVVGDIPGFADSLLRGWQAKKRTSTRISNPAIEHAYQVAQSSGMVAGKVSGAGGGGFLMMIVDPRRRIEVARSLERE 323
Cdd:COG2605 231 KEALLKGDLDEFGELLNEGWELKKRLASGISNPAIDEIYELARKAGALGGKLLGAGGGGFLLFYAPPERREAVREALSKA 310

                       330
                ....*....|....*....
gi 15607257 324 cGGSVAPCLFTKGGAVTWH 342
Cdd:COG2605 311 -GLRVVPFSFDKEGSQVWR 328
ERG12 COG1577
Mevalonate kinase [Lipid transport and metabolism]; Mevalonate kinase is part of the Pathway ...
 28-296 6.09e-17

Mevalonate kinase [Lipid transport and metabolism]; Mevalonate kinase is part of the Pathway/BioSystem: Isoprenoid biosynthesis


Pssm-ID: 441185 [Multi-domain]  Cd Length: 277  Bit Score: 80.27  E-value: 6.09e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15607257  28 FGGRILSVTIDKYAYAFAERGTGDEIAFRSPDrdraGQASIDDLASLEEDF-PLHVAVyrRVIAEFNGGTPFPLQLATQV 106
Cdd:COG1577  15 YGQPAIAVAVDRRATVTVEPSDDDKLRIESPD----LGGTLDLDPLADAALrYIKAAI--EAALEYLGLPLKGFDIEIDS 88

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15607257 107 DAPPGSGLGSSSALVVAMLLTTCALIGSSPGPYELARLAWEIERVDLGMAGGwQDHYAAAFGGFNFMESRPNGEvvvnPL 186
Cdd:COG1577  89 EIPRKRGLGSSAAVAVAVIRALAAFYGVELSKEELFKLALEAEKIVHGNPSG-LDTAASTYGGPIYYQRGDRAE----PL 163

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15607257 187 RIRREViaeleaSLLLYFGGVSRLSSEVIAD------QQRNVVERDADALAATHSICAEALEMKDLLVVGDIPGFADSLL 260
Cdd:COG1577 164 ELPKNL------PLVVGDTGVPASTKELVAKvrklkeRNPELYEAFLEEIGDLVEEAIEALEEGDLEALGELMNENHGLL 237

                       250       260       270
                ....*....|....*....|....*....|....*.
gi 15607257 261 RGWQakkrtstrISNPAIEHAYQVAQSSGMVAGKVS 296
Cdd:COG1577 238 RALG--------VSTPELDRLVEAARKAGALGAKLT 265
GalK COG0153
Galactokinase [Carbohydrate transport and metabolism];
29-173 3.03e-13

Galactokinase [Carbohydrate transport and metabolism];


Pssm-ID: 439923 [Multi-domain]  Cd Length: 380  Bit Score: 70.19  E-value: 3.03e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15607257  29 GGRILSVTIDKYAYAFAERGTGDEIAFRSPDRDRAGQASIDDLASLEEDfplHVAVY-RRVIAEFN--GGTPFPLQLATQ 105
Cdd:COG0153  38 GGFVLPAAIDRGTYAAARPRDDRKVRVYSADFDEEVEFDLDDLEPGEED---GWANYvRGVAWALQerGYKLGGFDLVID 114

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15607257 106 VDAPPGSGLGSSSALVVAMLLTTCALIGSSPGPYELARLAWEIERVDLGMAGGWQDHYAAAFGGFNFM 173
Cdd:COG0153 115 GDVPLGAGLSSSAALEVAVALALNDLFGLGLDPVELAKIGQRAENEFVGVPCGIMDQFASALGKKGHA 182
fkp PRK13412
bifunctional fucokinase/L-fucose-1-P-guanylyltransferase; Provisional
 72-320 2.60e-11

bifunctional fucokinase/L-fucose-1-P-guanylyltransferase; Provisional


Pssm-ID: 237379 [Multi-domain]  Cd Length: 974  Bit Score: 65.24  E-value: 2.60e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15607257   72 ASLEEdfplhvavyrrVIAEFNGGtpfpLQLATQVDAPPGSGLGSSSALVVAMLLTTCALIGSSPGPYELARLAWEIERV 151
Cdd:PRK13412 714 ASLEE-----------QLKAFGSG----IEITLLAAIPAGSGLGTSSILAATVLGAISDFCGLAWDKNEICNRTLVLEQL 778

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15607257  152 dLGMAGGWQDHYAAAFGGFNFMESRP--NGEVVVNPLRIRREVIAELEASLLLYFGGVSRLSSEVIADQQRNVVERDADA 229
Cdd:PRK13412 779 -LTTGGGWQDQYGGVLPGVKLLQTGAgfAQSPLVRWLPDSLFTQPEYRDCHLLYYTGITRTAKGILAEIVRSMFLNSTAH 857

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15607257  230 LAATHSICAEALEMKDLLVVGDIPGFADSLLRGWQAKKRTSTRISNPAIEHAYQVAQSSGMVAgKVSGAGGGGFLMMIV- 308
Cdd:PRK13412 858 LQLLHEMKAHALDMYEAIQRGEFEEFGRLVGKTWEQNKALDSGTNPAAVEAIIELIKDYTLGY-KLPGAGGGGYLYMVAk 936

                        250
                 ....*....|..
gi 15607257  309 DPRRRIEVARSL 320
Cdd:PRK13412 937 DPGAAERIRKIL 948
GHMP_kinases_N pfam00288
GHMP kinases N terminal domain; This family includes homoserine kinases, galactokinases and ...
 107-169 1.69e-10

GHMP kinases N terminal domain; This family includes homoserine kinases, galactokinases and mevalonate kinases.


Pssm-ID: 395225 [Multi-domain]  Cd Length: 64  Bit Score: 56.40  E-value: 1.69e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15607257   107 DAPPGSGLGSSSALVVAMLLTTCALIGSspgpyELARLAWEIERVDLGMAGGWQDHYAAAFGG 169
Cdd:pfam00288   7 NIPLGAGLGSSAALAVALLLALNELFGL-----PLAKLALEAEELAGGGRGGGMDVAASLYGG 64
mevalon_kin TIGR00549
mevalonate kinase; This model represents mevalonate kinase, the third step in the mevalonate ...
 81-296 4.65e-08

mevalonate kinase; This model represents mevalonate kinase, the third step in the mevalonate pathway of isopentanyl pyrophosphate (IPP) biosynthesis. IPP is a common intermediate for a number of pathways including cholesterol biosynthesis. This model covers enzymes from eukaryotes, archaea and bacteria. The related enzyme from the same pathway, phosphmevalonate kinase, serves as an outgroup for this clade. Paracoccus exhibits two genes within the phosphomevalonate/mevalonate kinase family, one of which falls between trusted and noise cutoffs of this model. The degree of divergence is high, but if the trees created from this model are correct, the proper names of these genes have been swapped. [Central intermediary metabolism, Other]


Pssm-ID: 273130 [Multi-domain]  Cd Length: 273  Bit Score: 53.83  E-value: 4.65e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15607257    81 HVAVYRRVIAEFNGGTPFPLQLATQVDAPPGSGLGSSSALVVAMLLTTCALIGSSPGPYELARLAWEIERVDLGMAGGwQ 160
Cdd:TIGR00549  60 LKYVLAEFLSRFSELNPPPLEITIESEIPPGRGLGSSAAVAVALIRALADYFGSELSKEELAELANEAEKIAHGKPSG-I 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15607257   161 DHYAAAFGGFNFMESRPNgevvvnplriRREVIAELEASLLLYFGGVSRLSSEVIADqQRNVVERDADALAATHSICAE- 239
Cdd:TIGR00549 139 DTATSTSGGPVYFEKGEG----------EFTKLISLDGYFVIADTGVSGSTKEAVAR-VRQLLERFPELIDSIMDAIGEl 207

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15607257   240 ------ALEMKDLLVVGDIPGFADSLLRgwqakkrtSTRISNPAIEHAYQVAQSSGMVAGKVS 296
Cdd:TIGR00549 208 tleakaALQDGDVESLGELMNINQGLLK--------ALGVSHPKLDQLVEIARKAGALGAKLT 262
PduX COG4542
PduX protein involved in propanediol utilization and related proteins [Secondary metabolites ...
 28-152 5.55e-08

PduX protein involved in propanediol utilization and related proteins [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443608 [Multi-domain]  Cd Length: 286  Bit Score: 53.70  E-value: 5.55e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15607257  28 FGGRILSVT--IDKYAYAFAERGTGdeiaFRSPDRDRAGQASiddlasleedfplhvavyRRVIAEFnGGTPFPLQLATQ 105
Cdd:COG4542  20 IGGREFLVTcpIDLYSTVTVEPGPG----GIPAERPKARRAA------------------ELTLEHL-GLPPLGGRIELR 76

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*..
gi 15607257 106 VDAPPGSGLGSSSALVVAMLLTTCALIGSSPGPYELARLAWEIERVD 152
Cdd:COG4542  77 SDIPVGKGMASSTADIAATARAVARALGKELSPEELARLAVAIEPTD 123
ThrB COG0083
Homoserine kinase [Amino acid transport and metabolism]; Homoserine kinase is part of the ...
 82-183 7.39e-07

Homoserine kinase [Amino acid transport and metabolism]; Homoserine kinase is part of the Pathway/BioSystem: Threonine biosynthesis


Pssm-ID: 439853 [Multi-domain]  Cd Length: 302  Bit Score: 50.48  E-value: 7.39e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15607257  82 VAVYRRVIAEFnGGTPFPLQLATQVDAPPGSGLGSSSALVVAMLLTTCALIGSSPGPYELARLAWEIERvdlgmaggwqd 161
Cdd:COG0083  62 YQAALALLEKL-GKEPPGLRIEIEKGIPLGRGLGSSAAAIVAGLVAANALLGLPLSKEELLELATEGEG----------- 129

                        90       100
                ....*....|....*....|....*.
gi 15607257 162 HY----AAAFGGFNFMESRPNGEVVV 183
Cdd:COG0083 130 HPdnvaPALLGGLVLSRSDGEPVRVV 155
PRK03926 PRK03926
mevalonate kinase; Provisional
 87-217 1.35e-05

mevalonate kinase; Provisional


Pssm-ID: 179677 [Multi-domain]  Cd Length: 302  Bit Score: 46.58  E-value: 1.35e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15607257   87 RVIAEFNGgtpfpLQLATQVDAPPGSGLGSSSALVVAMLLTTCALIGSSPGPYELARLAWEIERVDLGMAGGwQDHYAAA 166
Cdd:PRK03926  68 REEADKDG-----VTVSITSQIPVGSGLGSSAAVTVATIGALNRLLGLGLSLEEIAKLGHKVELLVQGAASP-TDTYVST 141

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15607257  167 FGGFNFMESR-------------------PNGEVVVNpLRIRREVIAELEASLLLYFGGVSRLSSEVIAD 217
Cdd:PRK03926 142 MGGFVTIPDRkklpfpecgivvgytgssgSTKELVAN-VRKLKEEYPELIEPILSSIGKISEKGEELILS 210
PRK03817 PRK03817
galactokinase; Provisional
 88-168 4.36e-05

galactokinase; Provisional


Pssm-ID: 235163 [Multi-domain]  Cd Length: 351  Bit Score: 44.99  E-value: 4.36e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15607257   88 VIAEF--NGGTPFPLQLATQVDAPPGSGLGSSSALVVAMLLTTCALIGSSPGPYELARLAWEIERVDLGMAGGWQDHYAA 165
Cdd:PRK03817  73 VIWVLekRGYEVGGVKGKVSSNLPIGAGLSSSASLEVAVAYALNEAYNLNLSKLELALLAREAENEFVGVPCGIMDQFAV 152


                 ...
gi 15607257  166 AFG 168
Cdd:PRK03817 153 AFG 155
PRK01212 PRK01212
homoserine kinase; Provisional
 82-183 1.95e-04

homoserine kinase; Provisional


Pssm-ID: 234920 [Multi-domain]  Cd Length: 301  Bit Score: 42.83  E-value: 1.95e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15607257   82 VAVYRRVIAEFngGTPFPLQLATQVDAPPGSGLGSSSALVVAMLLTTCALIGSSPGPYELARLAWEIERvdlgmaggwqd 161
Cdd:PRK01212  66 YQAALKFLEKL--GKPPGLRIELEKNIPLGRGLGSSAASIVAGLVAANELAGLPLSKEELLQLATEGEG----------- 132

                         90       100
                 ....*....|....*....|....*.
gi 15607257  162 HY----AAAFGGFNFMESRPNGEVVV 183
Cdd:PRK01212 133 HPdnvaPALLGGLVLALEENGVISVK 158
PRK00555 PRK00555
galactokinase; Provisional
 107-168 5.54e-04

galactokinase; Provisional


Pssm-ID: 179063 [Multi-domain]  Cd Length: 363  Bit Score: 41.77  E-value: 5.54e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15607257  107 DAPPGSGLGSSSALVVAMLLTTCALIGSSPGPYELARLAWEIERVDLGMAGGWQDHYAAAFG 168
Cdd:PRK00555  99 DVEIGSGLSSSAALECAVLGAVGAATGTRIDRLEQARLAQRAENEYVGAPTGLLDQLAALFG 160
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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