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Conserved domains on  [gi|15595209|ref|NP_248701|]
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lipid A biosynthesis lauroyl acyltransferase [Pseudomonas aeruginosa PAO1]

Protein Classification

lysophospholipid acyltransferase family protein( domain architecture ID 10792591)

lysophospholipid acyltransferase (LPLAT) family protein may act as an acyltransferase of a de novo or remodeling pathway of glycerophospholipid biosynthesis, catalyzing the incorporation of an acyl group from either acyl-CoAs or acyl-acyl carrier proteins (acyl-ACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid; similar to Pseudomonas aeruginosa lipid A biosynthesis lauroyl acyltransferase

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK05645 PRK05645
lysophospholipid acyltransferase;
1-295 0e+00

lysophospholipid acyltransferase;


:

Pssm-ID: 135493 [Multi-domain]  Cd Length: 295  Bit Score: 586.49  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209    1 MEKFKGALVVGALRLFALLPWRAVQGVGAGIGWLMWKLPNRSREVVRINLSKCFPELSETELEKLVGQSLMDIGRTLTES 80
Cdd:PRK05645   1 MEKFKGALMVGALRLFALLPWRAVQGVGAGIGWLMWKLPNRSREVVRINLSKCFPELSPAELEKLVGQSLMDIGKTLTES 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209   81 ACAWIWPPEKSLRYIREVEGMEVLEEALASGDGLVGITSHLGNWEVLNHFYCSYAKPIIFYRPPKLKAVDELLKKQRVQL 160
Cdd:PRK05645  81 ACAWIWPPQKSLELVREVEGLEVLEQALASGKGVVGITSHLGNWEVLNHFYCSQCKPIIFYRPPKLKAVDELLRKQRVQL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209  161 GNRVAPSTPEGILSVIKEVKKGGCVGIPADPEPARTAGLFVPYLGTTALISKFVPQLLSRGKARGVFFHAVRLPDGSGYK 240
Cdd:PRK05645 161 GNRVAPSTKEGILSVIKEVRKGGQVGIPADPEPAESAGIFVPFLGTQALTSKFVPNMLAGGKAVGVFLHALRLPDGSGYK 240

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 15595209  241 VILEAAPADMYDKDLEVSVAAMSRELAKYVRAYPSQYMWSMKRFKNRPDGEKKWY 295
Cdd:PRK05645 241 VILEAAPEDMYSTDVEVSAAAMSKVVERYVRAYPSQYMWSMKRFKKRPAGEARWY 295
 
Name Accession Description Interval E-value
PRK05645 PRK05645
lysophospholipid acyltransferase;
1-295 0e+00

lysophospholipid acyltransferase;


Pssm-ID: 135493 [Multi-domain]  Cd Length: 295  Bit Score: 586.49  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209    1 MEKFKGALVVGALRLFALLPWRAVQGVGAGIGWLMWKLPNRSREVVRINLSKCFPELSETELEKLVGQSLMDIGRTLTES 80
Cdd:PRK05645   1 MEKFKGALMVGALRLFALLPWRAVQGVGAGIGWLMWKLPNRSREVVRINLSKCFPELSPAELEKLVGQSLMDIGKTLTES 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209   81 ACAWIWPPEKSLRYIREVEGMEVLEEALASGDGLVGITSHLGNWEVLNHFYCSYAKPIIFYRPPKLKAVDELLKKQRVQL 160
Cdd:PRK05645  81 ACAWIWPPQKSLELVREVEGLEVLEQALASGKGVVGITSHLGNWEVLNHFYCSQCKPIIFYRPPKLKAVDELLRKQRVQL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209  161 GNRVAPSTPEGILSVIKEVKKGGCVGIPADPEPARTAGLFVPYLGTTALISKFVPQLLSRGKARGVFFHAVRLPDGSGYK 240
Cdd:PRK05645 161 GNRVAPSTKEGILSVIKEVRKGGQVGIPADPEPAESAGIFVPFLGTQALTSKFVPNMLAGGKAVGVFLHALRLPDGSGYK 240

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 15595209  241 VILEAAPADMYDKDLEVSVAAMSRELAKYVRAYPSQYMWSMKRFKNRPDGEKKWY 295
Cdd:PRK05645 241 VILEAAPEDMYSTDVEVSAAAMSKVVERYVRAYPSQYMWSMKRFKKRPAGEARWY 295
LpxP COG1560
Palmitoleoyl-ACP: Kdo2-lipid-IV acyltransferase (lipid A biosynthesis) [Lipid transport and ...
 12-284 3.98e-83

Palmitoleoyl-ACP: Kdo2-lipid-IV acyltransferase (lipid A biosynthesis) [Lipid transport and metabolism]; Palmitoleoyl-ACP: Kdo2-lipid-IV acyltransferase (lipid A biosynthesis) is part of the Pathway/BioSystem: Lipid A biosynthesis


Pssm-ID: 441168 [Multi-domain]  Cd Length: 271  Bit Score: 251.26  E-value: 3.98e-83
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209  12 ALRLFALLPWRAVQGVGAGIGWLMWKLPNRSREVVRINLSKCFPELSETELEKLVGQSLMDIGRTLTESACAWIWPPEKS 91
Cdd:COG1560   1 LLRLLRLLPLRLLYRLGDLLGRLLYRLAGRRRRVARRNLALAFPELSEAEREALARASFRNLGRTLLETLRLWRLSPERL 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209  92 LRYIrEVEGMEVLEEALASGDGLVGITSHLGNWEVLNHFYCSYAKPI-IFYRPPKLKAVDELLKKQRVQLGNRVAPsTPE 170
Cdd:COG1560  81 RKRV-EVEGLEHLEAALAEGRGVILLTPHFGNWELAGAALALRGYPVtAVYRPLKNPLLDRLIRRGRERFGGELIP-RKD 158

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209 171 GILSVIKEVKKGGCVGIPADPEPARTAGLFVPYLGTTALISKFVPQLLSRGKARGVFFHAVRLPDGSGYKVILEAAPADm 250
Cdd:COG1560 159 GVRALLRALRKGGIVGLLPDQDPGRKSGVFVPFFGVPAATPTGPARLARRTGAPVVPVFARRLPDGRGYRLEIEPPLED- 237

                       250       260       270
                ....*....|....*....|....*....|....
gi 15595209 251 YDKDLEVSVAAMSRELAKYVRAYPSQYMWSMKRF 284
Cdd:COG1560 238 FSEDVEADTQRLNRALEAWIREHPEQWLWLHRRW 271
Lip_A_acyltrans pfam03279
Bacterial lipid A biosynthesis acyltransferase;
8-285 5.59e-46

Bacterial lipid A biosynthesis acyltransferase;


Pssm-ID: 281296 [Multi-domain]  Cd Length: 294  Bit Score: 156.74  E-value: 5.59e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209     8 LVVGALRLFALLPWRAVQGVGAGIGWLMWKLPNRSREVVRINLSKCFPELSETELEKLVGQSLMDIGRTLTESACAWIWP 87
Cdd:pfam03279  17 LGIAVLRLLALLPYSALRRIGKGLGRLAGRFLKRRRKIARRNLALCFPEMSEAEREQIIDKSFASVGRAIVETGRVWFWP 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209    88 PEKSLRYIrEVEGMEVLEEALASGDGLVGITSHLGNWEVLNHFYCSYAKPIIFYRPPKLKA-VDELLKKQRVQLGNRVAP 166
Cdd:pfam03279  97 DSRIAKRF-EVIGLEHIKEALAQGRGAILVGPHFGNWDLGGRVLGQQYPGMAVYRPNLKNPlLDWLQTSGRERFGGRMLP 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209   167 STpEGILSVIKEVKKGGCVGIPADPEPARTAGLFVPYLG----TTALISKfvpqLLSRGKARGVFFHAVRLPDGSGYKVI 242
Cdd:pfam03279 176 RQ-NGIKGLIKALRKGEVVWYLPDQDLGRKDSVFVPFFGvpaaTTTGPAK----LALKTKAAVIPVFPIRNGDGSGYTVI 250

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 15595209   243 LEAAPADMYDKDLEVSVAAMSRELAKYVRAYPSQYMWSMKRFK 285
Cdd:pfam03279 251 VHPALDLTITDDVEQIAQAMNQIVEKFIMPAPEQYFWLHRRWK 293
lipid_A_htrB TIGR02207
lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase; This model represents a narrow ...
 8-295 2.82e-44

lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase; This model represents a narrow clade of acyltransferases, nearly all of which transfer a lauroyl group to KDO2-lipid IV-A, a lipid A precursor; these proteins are termed lipid A biosynthesis lauroyl acyltransferase, HtrB. An exception is a closely related paralog of E. coli HtrB, LpxP, which acts in cold shock conditions by transferring a palmitoleoyl rather than lauroyl group to the lipid A precursor. Members of this family are homologous to the family of acyltransferases responsible for the next step in lipid A biosynthesis. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 274031 [Multi-domain]  Cd Length: 303  Bit Score: 152.49  E-value: 2.82e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209     8 LVVGALRLFALLPWRAVQGVGAGIGWLMWKLPNRSREVVRINLSKCFPELSETELEKLVGQSLMDIGRTLTESACAWIWp 87
Cdd:TIGR02207  17 LGLGVLWLIVQLPYPVLLALGRGIGRLAMRLMKRRVHIARRNLELCFPHMSDAERERLLRENFESTGMALFETGMAWFW- 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209    88 PEKSLRYIREVEGMEVLEEALASGDGLVGITSHLGNWEVLNHFYCSYAKPIIFYRPPKLKAVDELLKKQRVQLGNRVAPS 167
Cdd:TIGR02207  96 SDARIKKWMQIEGLEHLQRAQKQGRGVLLVGVHFLTLELGARIFGQQQPGIGVYRPHNNPLFDWIQTRGRLRSNKAMIDR 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209   168 tpEGILSVIKEVKKGGCVGIPADPEPARTAGLFVPYLG------TTAliskfVPQLLSRGKARGVFFHAVRLPDGSGYKV 241
Cdd:TIGR02207 176 --KDLRGMIKALKNGERIWYAPDHDYGRKSSVFVPFFAvpdaatTTG-----TSILARLSKCAVVPFTPRRNEDGSGYRL 248

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 15595209   242 ILeAAPADMYDKDLEVSVAA-MSRELAKYVRAYPSQYMWSMKRFKNRPD-GEKKWY 295
Cdd:TIGR02207 249 KI-DPPLDDFPGDDEIAAAArMNKIVEKMIMRAPEQYMWLHRRFKTRPDeGESSLY 303
LPLAT_LABLAT-like cd07984
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; ...
 97-285 2.61e-42

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as lipid A biosynthesis lauroyl/myristoyl (LABLAT, HtrB) acyltransferases and similar proteins.


Pssm-ID: 153246 [Multi-domain]  Cd Length: 192  Bit Score: 143.89  E-value: 2.61e-42
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209  97 EVEGMEVLEEALASGDGLVGITSHLGNWEVLNHFYCSYAKPI-IFYRPPKLKAVDELLKKQRVQLGNRVAPSTpEGILSV 175
Cdd:cd07984   5 EREGLEHLEAALAKGKGVILLTAHFGNWELAGLALALLGYPVtVVYRPLKNPLLDRLITRGRERFGARLIPRG-GGLREL 83

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209 176 IKEVKKGGCVGIPADPEPARTAGLFVPYLGTTALISKFVPQLLSRGKARGVFFHAVRLPDGsGYKVILEAAPADMYDKDL 255
Cdd:cd07984  84 IRALKKGEIVGILPDQDPGRKGGVFVPFFGRPAATPTGPARLALKTGAPVVPAFAYRLPGG-GYRIEFEPPLENPPSEDV 162

                       170       180       190
                ....*....|....*....|....*....|
gi 15595209 256 EVSVAAMSRELAKYVRAYPSQYMWSMKRFK 285
Cdd:cd07984 163 EEDTQRLNDALEAAIREHPEQWLWFHRRWK 192
 
Name Accession Description Interval E-value
PRK05645 PRK05645
lysophospholipid acyltransferase;
1-295 0e+00

lysophospholipid acyltransferase;


Pssm-ID: 135493 [Multi-domain]  Cd Length: 295  Bit Score: 586.49  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209    1 MEKFKGALVVGALRLFALLPWRAVQGVGAGIGWLMWKLPNRSREVVRINLSKCFPELSETELEKLVGQSLMDIGRTLTES 80
Cdd:PRK05645   1 MEKFKGALMVGALRLFALLPWRAVQGVGAGIGWLMWKLPNRSREVVRINLSKCFPELSPAELEKLVGQSLMDIGKTLTES 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209   81 ACAWIWPPEKSLRYIREVEGMEVLEEALASGDGLVGITSHLGNWEVLNHFYCSYAKPIIFYRPPKLKAVDELLKKQRVQL 160
Cdd:PRK05645  81 ACAWIWPPQKSLELVREVEGLEVLEQALASGKGVVGITSHLGNWEVLNHFYCSQCKPIIFYRPPKLKAVDELLRKQRVQL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209  161 GNRVAPSTPEGILSVIKEVKKGGCVGIPADPEPARTAGLFVPYLGTTALISKFVPQLLSRGKARGVFFHAVRLPDGSGYK 240
Cdd:PRK05645 161 GNRVAPSTKEGILSVIKEVRKGGQVGIPADPEPAESAGIFVPFLGTQALTSKFVPNMLAGGKAVGVFLHALRLPDGSGYK 240

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 15595209  241 VILEAAPADMYDKDLEVSVAAMSRELAKYVRAYPSQYMWSMKRFKNRPDGEKKWY 295
Cdd:PRK05645 241 VILEAAPEDMYSTDVEVSAAAMSKVVERYVRAYPSQYMWSMKRFKKRPAGEARWY 295
LpxP COG1560
Palmitoleoyl-ACP: Kdo2-lipid-IV acyltransferase (lipid A biosynthesis) [Lipid transport and ...
 12-284 3.98e-83

Palmitoleoyl-ACP: Kdo2-lipid-IV acyltransferase (lipid A biosynthesis) [Lipid transport and metabolism]; Palmitoleoyl-ACP: Kdo2-lipid-IV acyltransferase (lipid A biosynthesis) is part of the Pathway/BioSystem: Lipid A biosynthesis


Pssm-ID: 441168 [Multi-domain]  Cd Length: 271  Bit Score: 251.26  E-value: 3.98e-83
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209  12 ALRLFALLPWRAVQGVGAGIGWLMWKLPNRSREVVRINLSKCFPELSETELEKLVGQSLMDIGRTLTESACAWIWPPEKS 91
Cdd:COG1560   1 LLRLLRLLPLRLLYRLGDLLGRLLYRLAGRRRRVARRNLALAFPELSEAEREALARASFRNLGRTLLETLRLWRLSPERL 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209  92 LRYIrEVEGMEVLEEALASGDGLVGITSHLGNWEVLNHFYCSYAKPI-IFYRPPKLKAVDELLKKQRVQLGNRVAPsTPE 170
Cdd:COG1560  81 RKRV-EVEGLEHLEAALAEGRGVILLTPHFGNWELAGAALALRGYPVtAVYRPLKNPLLDRLIRRGRERFGGELIP-RKD 158

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209 171 GILSVIKEVKKGGCVGIPADPEPARTAGLFVPYLGTTALISKFVPQLLSRGKARGVFFHAVRLPDGSGYKVILEAAPADm 250
Cdd:COG1560 159 GVRALLRALRKGGIVGLLPDQDPGRKSGVFVPFFGVPAATPTGPARLARRTGAPVVPVFARRLPDGRGYRLEIEPPLED- 237

                       250       260       270
                ....*....|....*....|....*....|....
gi 15595209 251 YDKDLEVSVAAMSRELAKYVRAYPSQYMWSMKRF 284
Cdd:COG1560 238 FSEDVEADTQRLNRALEAWIREHPEQWLWLHRRW 271
PRK08905 PRK08905
lysophospholipid acyltransferase family protein;
8-290 2.50e-49

lysophospholipid acyltransferase family protein;


Pssm-ID: 236348 [Multi-domain]  Cd Length: 289  Bit Score: 165.16  E-value: 2.50e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209    8 LVVGALRLFALLPWRAVQGVGAGIGWLMWKLPNRSREVVRINLSKCFPElsetELEKLVGQSLMDIGRTLTESACAWIWP 87
Cdd:PRK08905   1 LLTFLFRLLSRLPLSWLHALGGWLGRLAYRLPGRYRRRLRANLRQAGGD----PDPAMVKAAAAETGRMILELPYVWFRK 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209   88 PEKSLRYIREVEGMEVLEEALASGDGLVGITSHLGNWEVLNHFYCSYAKPIIFYRPPKLKAVDELLKKQRVQLGNRVAPS 167
Cdd:PRK08905  77 PEEIETMVKDDHGWEHVEAALAEGRGILFLTPHLGCFEVTARYIAQRFPLTAMFRPPRKAALRPLMEAGRARGNMRTAPA 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209  168 TPEGILSVIKEVKKGGCVGIPADPEPARTAGLFVPYLGTTALISKFVPQLLSRGKARGVFFHAVRLPDGSGYKVILEaAP 247
Cdd:PRK08905 157 TPQGVRMLVKALRRGEAVGILPDQVPSGGEGVWAPFFGRPAYTMTLVARLAEVTGVPVIFVAGERLPRGRGYRLHLR-PV 235

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 15595209  248 ADMYDKDLEVSVAAMSRELAKYVRAYPSQYMWSMKRFKnRPDG 290
Cdd:PRK08905 236 QEPLPGDKAADAAVINAEIERLIRRFPTQYLWGYNRYK-RPRG 277
Lip_A_acyltrans pfam03279
Bacterial lipid A biosynthesis acyltransferase;
8-285 5.59e-46

Bacterial lipid A biosynthesis acyltransferase;


Pssm-ID: 281296 [Multi-domain]  Cd Length: 294  Bit Score: 156.74  E-value: 5.59e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209     8 LVVGALRLFALLPWRAVQGVGAGIGWLMWKLPNRSREVVRINLSKCFPELSETELEKLVGQSLMDIGRTLTESACAWIWP 87
Cdd:pfam03279  17 LGIAVLRLLALLPYSALRRIGKGLGRLAGRFLKRRRKIARRNLALCFPEMSEAEREQIIDKSFASVGRAIVETGRVWFWP 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209    88 PEKSLRYIrEVEGMEVLEEALASGDGLVGITSHLGNWEVLNHFYCSYAKPIIFYRPPKLKA-VDELLKKQRVQLGNRVAP 166
Cdd:pfam03279  97 DSRIAKRF-EVIGLEHIKEALAQGRGAILVGPHFGNWDLGGRVLGQQYPGMAVYRPNLKNPlLDWLQTSGRERFGGRMLP 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209   167 STpEGILSVIKEVKKGGCVGIPADPEPARTAGLFVPYLG----TTALISKfvpqLLSRGKARGVFFHAVRLPDGSGYKVI 242
Cdd:pfam03279 176 RQ-NGIKGLIKALRKGEVVWYLPDQDLGRKDSVFVPFFGvpaaTTTGPAK----LALKTKAAVIPVFPIRNGDGSGYTVI 250

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 15595209   243 LEAAPADMYDKDLEVSVAAMSRELAKYVRAYPSQYMWSMKRFK 285
Cdd:pfam03279 251 VHPALDLTITDDVEQIAQAMNQIVEKFIMPAPEQYFWLHRRWK 293
PRK08734 PRK08734
lauroyl acyltransferase;
5-290 1.03e-45

lauroyl acyltransferase;


Pssm-ID: 181543 [Multi-domain]  Cd Length: 305  Bit Score: 156.20  E-value: 1.03e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209    5 KGALVVGALRLFALLPWRAVQGVGAGIGWLMWKLPNRSREVVRINLSKCFPELSETELEKLVGQSLMDIGRTLTESACAW 84
Cdd:PRK08734   6 KARLLYRTAALVGRLPWPLLKRLADLLAWSWRKLNARESRVTRRNLELAYPELSPQQRAQLHAQILRSTARQALEVLRTW 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209   85 IWPPEKSLRYIREVEGMEVLEEALASGDGLVGITSHLGNWEVLNHFYCSYAKPIIFYRPPKLKAVDELLkkQRVQLGNRV 164
Cdd:PRK08734  86 THPPAENLARLRQRHGQELYDAALASGRGVIVAAPHFGNWELLNQWLSERGPIAIVYRPPESEAVDGFL--QLVRGGDNV 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209  165 APSTPEG--ILSVIKEVKKGGCVGIPADPEPARTAGLFVPYLGTTALISKFVPQLLSRGKARGVFFHAVRLPDGSGYKVI 242
Cdd:PRK08734 164 RQVRAEGpaVRQLFKVLKDGGAVGILPDQQPKMGDGVFAPFFGIPALTMTLVNRLAERTGATVLYGWCERIGPDLEFALH 243

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 15595209  243 LEAAPADMYDKDLEVSVAAMSRELAKYVRAYPSQYMWSMKRFKNRPDG 290
Cdd:PRK08734 244 VQPADPAVADPDPLRAATALNAGIERIARRDPAQYQWTYKRYTLRPPG 291
lipid_A_htrB TIGR02207
lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase; This model represents a narrow ...
 8-295 2.82e-44

lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase; This model represents a narrow clade of acyltransferases, nearly all of which transfer a lauroyl group to KDO2-lipid IV-A, a lipid A precursor; these proteins are termed lipid A biosynthesis lauroyl acyltransferase, HtrB. An exception is a closely related paralog of E. coli HtrB, LpxP, which acts in cold shock conditions by transferring a palmitoleoyl rather than lauroyl group to the lipid A precursor. Members of this family are homologous to the family of acyltransferases responsible for the next step in lipid A biosynthesis. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 274031 [Multi-domain]  Cd Length: 303  Bit Score: 152.49  E-value: 2.82e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209     8 LVVGALRLFALLPWRAVQGVGAGIGWLMWKLPNRSREVVRINLSKCFPELSETELEKLVGQSLMDIGRTLTESACAWIWp 87
Cdd:TIGR02207  17 LGLGVLWLIVQLPYPVLLALGRGIGRLAMRLMKRRVHIARRNLELCFPHMSDAERERLLRENFESTGMALFETGMAWFW- 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209    88 PEKSLRYIREVEGMEVLEEALASGDGLVGITSHLGNWEVLNHFYCSYAKPIIFYRPPKLKAVDELLKKQRVQLGNRVAPS 167
Cdd:TIGR02207  96 SDARIKKWMQIEGLEHLQRAQKQGRGVLLVGVHFLTLELGARIFGQQQPGIGVYRPHNNPLFDWIQTRGRLRSNKAMIDR 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209   168 tpEGILSVIKEVKKGGCVGIPADPEPARTAGLFVPYLG------TTAliskfVPQLLSRGKARGVFFHAVRLPDGSGYKV 241
Cdd:TIGR02207 176 --KDLRGMIKALKNGERIWYAPDHDYGRKSSVFVPFFAvpdaatTTG-----TSILARLSKCAVVPFTPRRNEDGSGYRL 248

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 15595209   242 ILeAAPADMYDKDLEVSVAA-MSRELAKYVRAYPSQYMWSMKRFKNRPD-GEKKWY 295
Cdd:TIGR02207 249 KI-DPPLDDFPGDDEIAAAArMNKIVEKMIMRAPEQYMWLHRRFKTRPDeGESSLY 303
LPLAT_LABLAT-like cd07984
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; ...
 97-285 2.61e-42

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as lipid A biosynthesis lauroyl/myristoyl (LABLAT, HtrB) acyltransferases and similar proteins.


Pssm-ID: 153246 [Multi-domain]  Cd Length: 192  Bit Score: 143.89  E-value: 2.61e-42
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209  97 EVEGMEVLEEALASGDGLVGITSHLGNWEVLNHFYCSYAKPI-IFYRPPKLKAVDELLKKQRVQLGNRVAPSTpEGILSV 175
Cdd:cd07984   5 EREGLEHLEAALAKGKGVILLTAHFGNWELAGLALALLGYPVtVVYRPLKNPLLDRLITRGRERFGARLIPRG-GGLREL 83

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209 176 IKEVKKGGCVGIPADPEPARTAGLFVPYLGTTALISKFVPQLLSRGKARGVFFHAVRLPDGsGYKVILEAAPADMYDKDL 255
Cdd:cd07984  84 IRALKKGEIVGILPDQDPGRKGGVFVPFFGRPAATPTGPARLALKTGAPVVPAFAYRLPGG-GYRIEFEPPLENPPSEDV 162

                       170       180       190
                ....*....|....*....|....*....|
gi 15595209 256 EVSVAAMSRELAKYVRAYPSQYMWSMKRFK 285
Cdd:cd07984 163 EEDTQRLNDALEAAIREHPEQWLWFHRRWK 192
PRK05646 PRK05646
lipid A biosynthesis lauroyl acyltransferase; Provisional
 8-295 1.88e-39

lipid A biosynthesis lauroyl acyltransferase; Provisional


Pssm-ID: 235543 [Multi-domain]  Cd Length: 310  Bit Score: 139.95  E-value: 1.88e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209    8 LVVGALRLFALLPWRAVQGVGAGIGWLMWKLPNRSREVVRINLSKCFPELSETELEKLVGQSLMDIGRTLTESACAWIWP 87
Cdd:PRK05646  20 LGLGLLWLVVQLPYRVLLWLGRALGALMYRLAGSRRRIAARNLELCFPEKSAAERERLLKENFASTGIAFFEMAMSWWWP 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209   88 pEKSLRYIREVEGMEVLEEALASGDGLVGITSHLGNWEVLNHFYCSYAKPIIFYRPPKlKAVDELLKKQRVQLGNRVAPS 167
Cdd:PRK05646 100 -KARLARLAHIEGLEHLQQAQQEGQGVILMALHFTTLEIGAALLGQQHTIDGMYREHK-NPVFDFIQRRGRERHNLDSTA 177

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209  168 TP-EGILSVIKEVKKGGCVGIPADPEPARTAGLFVPYLGTTALISKFVPQLLSRGKARGVFFHAVRLPDGSGYKVILEAA 246
Cdd:PRK05646 178 IErEDVRGMLKLLRAGRAIWYAPDQDYGAKQSIFVPLFGIPAATVTATTKFARLGRARVIPFTQKRLADGSGYRLVIHPP 257

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 15595209  247 PADMYDKDLEVSVAAMSRELAKYVRAYPSQYMWSMKRFKNRPDGEKKWY 295
Cdd:PRK05646 258 LEDFPGESEEADCLRINQWVERVVRECPEQYLWAHRRFKSRPEGEPKLY 306
PRK06946 PRK06946
lipid A biosynthesis lauroyl acyltransferase; Provisional
 1-295 4.38e-39

lipid A biosynthesis lauroyl acyltransferase; Provisional


Pssm-ID: 180770 [Multi-domain]  Cd Length: 293  Bit Score: 138.66  E-value: 4.38e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209    1 MEKFKGALVVGALRLFALLPWRAVQGVGAGIGWLMWKLPNRSREVVRINLSKCFPELSETELEKLVGQSLMDIGRTLTES 80
Cdd:PRK06946   1 LGRLGTALAIGLLKLLAFLPYGLTARFGDGLGWLLYRIPSRRRRIVHTNLKLCFPDWSDARREELARRHFRHVIRSYVER 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209   81 ACAWiWPPEKSLRYIREVEGmevlEEALASGDG----LVGItsHLGNWEV----LNHfycSYAKPI-IFYRPPKLKAVDE 151
Cdd:PRK06946  81 SVQW-FGSEKKLEKLVQVDS----AIDLTDPDGpptiFLGL--HFVGIEAgsiwLNY---SLRRRVgSLYTPMSNPLLDA 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209  152 LLKKQRVQLGNRVAPSTpEGILSVIKEVKKGGCVGIPADPEPARTAGLFVPYLGTTALISKFVPQLLSRGKARGVFFHAV 231
Cdd:PRK06946 151 IAKAARGRFGAEMVSRA-DSARQVLRWLRDGKPVMLGADMDFGLRDSTFVPFFGVPACTLTAVSRLARTGGAQVVPFITE 229

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15595209  232 RLPDGSGYKVILEAAPADMYDKDLEVSVAAMSRELAKYVRAYPSQYMWSMKRFKNRPDGEKKWY 295
Cdd:PRK06946 230 VLPDYKGYRLRVFKPWENYPTGDDDLDARRMNAFLEEQIRLMPEQYYWVHKRFKTRPPGEPSVY 293
PRK06860 PRK06860
lipid A biosynthesis lauroyl acyltransferase; Provisional
 8-295 1.27e-35

lipid A biosynthesis lauroyl acyltransferase; Provisional


Pssm-ID: 235880 [Multi-domain]  Cd Length: 309  Bit Score: 130.03  E-value: 1.27e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209    8 LVVGALRLFALLPWRAVQGVGAGIGWLMWKLPNRSREVVRINLSKCFPELSETELEKLVGQSLMDIGRTLTESACAWIWP 87
Cdd:PRK06860  23 LGIGLLWLIVLLPYPVLYKLGRGLGKLALRFMKRRAKIARRNLELCFPEMSEQEREAIVVKNFESVGMALIETGMAWFWP 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209   88 PEKSLRYIrEVEGMEVLEEALASGDGLVGITSHLGNWEVLNHFYCSYAKPIIFYRPPKLKAVDELLKKQRVQLGNRVAPS 167
Cdd:PRK06860 103 DWRIKRWT-EVEGLEHIREVQAQGRGVLLVGVHFLTLELGARIFGMHNPGIGVYRPNDNPLYDWLQTWGRLRSNKSMLDR 181

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209  168 TpeGILSVIKEVKKGGCVGIPADPEPARTAGLFVPYLGttaliskfVPQ---------LLSRGKARGVFFHAVRLPDGSG 238
Cdd:PRK06860 182 K--DLKGMIKALKKGERIWYAPDHDYGPRSSVFVPFFA--------VEQaatttgtwmLARMSKAAVIPFVPRRKPDGKG 251

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 15595209  239 YKVILEAAPADMYDKDLEVSVAAMSRELAKYVRAYPSQYMWSMKRFKNRPDGEKKWY 295
Cdd:PRK06860 252 YELIILPPEDSPPLDDAEATAAWMNKVVEKCILMAPEQYMWLHRRFKTRPEGVPSRY 308
PRK08706 PRK08706
lipid A biosynthesis lauroyl acyltransferase; Provisional
 13-295 3.48e-31

lipid A biosynthesis lauroyl acyltransferase; Provisional


Pssm-ID: 169557 [Multi-domain]  Cd Length: 289  Bit Score: 117.66  E-value: 3.48e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209   13 LRLFALLPWRAVQGVGAGIGWLMWKLPNRSREVVRINLSKCFPELSETELEKLVGQSLMDIGRTLTESACAWiWPPEKSL 92
Cdd:PRK08706   8 LYVLQFLPFALLHKLADLTGLLAYLLVKPRRRIGEINLAKCFPEWDEEKRKTVLKQHFKHMAKLMLEYGLYW-YAPAGRL 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209   93 RYIREVEGMEVLEEALASGDGLVGITSHLGNWEVLNHFYCSYAKPIIFYRPPKLKAVDELLKKQRVQLGNRVAPSTPEGI 172
Cdd:PRK08706  87 KSLVRYRNKHYLDDALAAGEKVIILYPHFTAFEMAVYALNQDVPLISMYSHQKNKILDEQILKGRNRYHNVFLIGRTEGL 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209  173 LSVIKEVKKGGC--VGIPaDPEPARTAGLFVPYLGTTALISKFVPQLLSRGKARGVFFHAVRLPDGsgyKVILEAAPA-- 248
Cdd:PRK08706 167 RALVKQFRKSSApfLYLP-DQDFGRNDSVFVDFFGIQTATITGLSRIAALANAKVIPAIPVREADN---TVTLHFYPAwd 242

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 15595209  249 DMYDKDLEVSVAAMSRELAKYVRAYPSQYMWSMKRFKNRPDGEKKWY 295
Cdd:PRK08706 243 SFPSEDAQADAQRMNRFIEERVREHPEQYFWLHKRFKTRPEGSPDFY 289
PRK08733 PRK08733
LpxL/LpxP family Kdo(2)-lipid IV(A) lauroyl/palmitoleoyl acyltransferase;
8-295 2.31e-30

LpxL/LpxP family Kdo(2)-lipid IV(A) lauroyl/palmitoleoyl acyltransferase;


Pssm-ID: 181542 [Multi-domain]  Cd Length: 306  Bit Score: 116.16  E-value: 2.31e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209    8 LVVGALRLFALLPWRAVQGVGAGIGWLMWKLPNRSREVVRINLSKCFPELSETELEKLVGQSLMDIGRTLTESACAWiWP 87
Cdd:PRK08733  23 LGLAVMVLAARLPWTLQRALGRGVGWVAMRLAGTRRRAAEVNLKLCFPEQDDAWRARLLRDSFDALGVGLFEFARAW-WG 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209   88 PEKSLRYIREVEGMEVLEEALASGDGLVGITSHLGNWEVLNHFYCSYAKPIIFYRPPKLKAVDELLKKQRVQLGNRVAPS 167
Cdd:PRK08733 102 SIDVIRPGVQIEGLEHLQQLQQQGRGVLLVSGHFMTLEMCGRLLCDHVPLAGMYRRHRNPVFEWAVKRGRLRYATHMFAN 181

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209  168 tpEGILSVIKEVKKGGCVGIPADPEPARTAGLFVPYLGTTALISKFVPQLLS-RGKARGVFFHAVRlpdgsGYKVILEAA 246
Cdd:PRK08733 182 --EDLRATIKHLKRGGFLWYAPDQDMRGKDTVFVPFFGHPASTITATHQLARlTGCAVVPYFHRRE-----GGRYVLKIA 254

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|.
gi 15595209  247 P--ADMYDKDLEVSVAAMSRELAKYVRAYPSQYMWSMKRFKNRPDGEKKWY 295
Cdd:PRK08733 255 PplADFPSDDVIADTTRVNAAIEDMVREAPDQYLWIHRRFKRQPGGRSDFY 305
PRK08943 PRK08943
lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; Validated
 8-291 1.04e-27

lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; Validated


Pssm-ID: 236355  Cd Length: 314  Bit Score: 109.19  E-value: 1.04e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209    8 LVVGALRLFALLPWRAVQGVGAGIGWLMWKLPNRSREVVRINLSKCFPELSETELEKLV-------GQSLMDIGRTLTES 80
Cdd:PRK08943  28 LGIGALAGLALMPPRLRDPLAAKLGRLVGKLAKKARRRARINLSLCFPEKSEAEREAIIdemfataPQAMLMMAELALRS 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209   81 acawiwpPEKSLRYIrEVEGMEVLEEALASGDGLVGITSHlgNWEV------LNhfycSYAKPII-FYRPPKLKAVDELL 153
Cdd:PRK08943 108 -------PKHLQRRV-EWHGLEILEEARANGENVIFLVPH--GWAIdipamlLA----SQGQPMAaMFHNQRNPLFDWLW 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209  154 KKQRVQLGNRVApSTPEGILSVIKEVKKgGCVG--IPaDPEPARTAGLFVPYLGTTALISKFVPQLLSRGKARGVFFHAV 231
Cdd:PRK08943 174 NRVRRRFGGRLH-AREDGIKPFISSVRQ-GYWGyyLP-DEDHGPEHSVFVDFFATYKATLPGIGRLAKVCRARVVPLFPV 250

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209  232 RLPDGSGYKVILEAAPADMYDKDLEVSVAAMSRELAKYVRAYPSQYMWSMKRFKNRPDGE 291
Cdd:PRK08943 251 YNGKTHRLDIEIRPPMDDLLSADDETIARRMNEEVEQFVGPHPEQYMWILKLLKTRKPGE 310
PRK08025 PRK08025
kdo(2)-lipid IV(A) palmitoleoyltransferase;
10-295 3.09e-22

kdo(2)-lipid IV(A) palmitoleoyltransferase;


Pssm-ID: 181200  Cd Length: 305  Bit Score: 94.03  E-value: 3.09e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209   10 VGALRLFALLPWRAVQGVGAGIGWLMWKLPNRSREVVRINLSKCFPELSETELEKLVGQSLMDIGRTLTESACAWIWPPE 89
Cdd:PRK08025  23 LGVLWLLVQLPYPVLCFLGTRIGRMSRPFLKRRESIARKNLELCFPQMSAEEREKMIAENFRSLGMALLETGMAWFWPDS 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209   90 KSLRYIrEVEGMEVLEEALASGDGLVGITSHLGNWEvLNHFYCSYAKPII-FYRPPKLKAVDELLKKQRVQlGNRvAPST 168
Cdd:PRK08025 103 RVRKWF-DVEGLDNLKRAQMQNRGVMVVGVHFMSLE-LGGRVMGLCQPMMaTYRPHNNKLMEWVQTRGRMR-SNK-AMIG 178

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209  169 PEGILSVIKEVKKGGCVGIPADPEPARTAGLFVPYLGTTALISKFVPQLLSR-GKARGVFFHAVRLPDGSGYKVILEAAP 247
Cdd:PRK08025 179 RNNLRGIVGALKKGEAVWFAPDQDYGPKGSSFAPFFAVENVATTNGTYVLSRlSGAAMLTVTMVRKADYSGYRLFITPEM 258

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 15595209  248 ADmYDKDLEVSVAAMSRELAKYVRAYPSQYMWSMKRFKNRPDGEKKWY 295
Cdd:PRK08025 259 EG-YPTDENQAAAYMNKIIEKEIMRAPEQYLWIHRRFKTRPVGESSLY 305
PRK06553 PRK06553
lipid A biosynthesis lauroyl acyltransferase; Provisional
 6-283 2.36e-20

lipid A biosynthesis lauroyl acyltransferase; Provisional


Pssm-ID: 235827 [Multi-domain]  Cd Length: 308  Bit Score: 88.88  E-value: 2.36e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209    6 GALVVGALRLFALLPwraVQGVGAGIGWLMWKLPNRSRE--VVRINLSKCFPELSETELEKLVGQSLMDIGRTLTESA-- 81
Cdd:PRK06553  25 AQLVFGLLGLLRLFP---ADKAINFFGRLARLIGPLLPRhrVALDNLRAAFPEKSEAEIEAIALGMWDNLGRLGAEYAfl 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209   82 -CAWIWPPEKSLRYIREVEGMEVLEEALASGDGLVGITSHLGNWEVLnhfycsyakPI----------IFYRPPKLKAVD 150
Cdd:PRK06553 102 dAIFDYDPEAPEPGRVEVRGIEIFERLRDDGKPALIFTAHLGNWELL---------AIaaaafgldvtVLFRPPNNPYAA 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209  151 ELLKKQR-VQLGNRVaPSTPEGILSVIKEVKKGGCVGIPADPEPARtaGLFVPYLGTTALISKFVPQLlsrgkAR----- 224
Cdd:PRK06553 173 RKVLEARrTTMGGLV-PSGAGAAFALAGVLERGGHVGMLVDQKFTR--GVEVTFFGRPVKTNPLLAKL-----ARqydcp 244

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15595209  225 --GVffHAVRLPDGSgYKVILEAAPADMYDKDLEVSVAA----MSRELAKYVRAYPSQYMWSMKR 283
Cdd:PRK06553 245 vhGA--RCIRLPGGR-FRLELTERVELPRDADGQIDVQAtmqaLTDVVEGWVREYPGQWLWLHRR 306
PRK08419 PRK08419
lipid A biosynthesis lauroyl acyltransferase; Reviewed
 14-286 1.47e-16

lipid A biosynthesis lauroyl acyltransferase; Reviewed


Pssm-ID: 181420 [Multi-domain]  Cd Length: 298  Bit Score: 78.14  E-value: 1.47e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209   14 RLFALLPWRAVQGVGAGIGWLMWKLPNRSREVVRINLSKCFPE-LSETELEKLVGQSLMDIGRTLTESACAWIWPPEKSL 92
Cdd:PRK08419  15 FFLAKMPHCIFLRLAKALAFIMRYLDKKRRKIAKANLDFCFGEsKSQEEKKRIIKKCYENFAFFGLDFIRNQNTTKEEIL 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209   93 RYIrEVEGMEVLEEALASGDGLVGITSHLGNWEVLNHFYCSYAKPI-IFYRPPKLKAVDELLKKQRVQLGNRVAPSTpEG 171
Cdd:PRK08419  95 NKV-TFINEENLLDALKKKRPIIVTTAHYGYWELFSLALAAYYGAVsIVGRLLKSAPINEMISKRREQFGIELIDKK-GA 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209  172 ILSVIKEVKKGGCVGIPADPEPARTAGLFVPYLGTTALISKfVPQLLSRGkargvfFHAVRLP------DGSGYKVI-LE 244
Cdd:PRK08419 173 MKELLKALKQGRALGILVDQNVVPKEGVEVKFFNKRVTHTT-IASILARR------YNALIIPvfifndDYSHFTITfFP 245

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 15595209  245 AAPADMYDK---DLEVSVAAMSRELAKYVRAYPSQYMWSMKRFKN 286
Cdd:PRK08419 246 PIRSKITDDaeaDILEATQAQASACEEMIRKKPDEYFWFHRRFKS 290
COG4261 COG4261
Predicted acyltransferase, LPLAT superfamily [General function prediction only];
97-279 4.35e-11

Predicted acyltransferase, LPLAT superfamily [General function prediction only];


Pssm-ID: 443403  Cd Length: 300  Bit Score: 62.13  E-value: 4.35e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209  97 EVEGMEVLEEALASGDGLVGITSHLGNWEVLNHF---YCSYAKPIIFYRP--PKLKAVDELLKKQR----VQLGNRvaps 167
Cdd:COG4261 100 DVDGEELLRALLAQGRGGILLGAHLGNFEVLRALarrRPGLKINVLMHTEhaQKINRLLEALNPKSainiIQVGED---- 175

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209 168 tPEGILSVIKEVKKGGCVGIPAD--PEPARTAGlfVPYLGTTALIskfvPQ----LLSRGKARGVFFHAVRLPdGSGYKV 241
Cdd:COG4261 176 -PSTMLELKEALDRGELVAILGDrtPGGEKTVE--VDFLGAPAPF----PQgpflLAALLKVPVYLVFGLKEG-GNRYHL 247

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*
gi 15595209 242 ILEAApADMYDK-------DLEVSVAAMSRELAKYVRAYPsqYMW 279
Cdd:COG4261 248 YFEPF-ADFLDLprkereaALQELLQRYAARLEHYCRKAP--YQW 289
PRK06628 PRK06628
lipid A biosynthesis lauroyl acyltransferase; Provisional
 44-285 6.97e-10

lipid A biosynthesis lauroyl acyltransferase; Provisional


Pssm-ID: 102471  Cd Length: 290  Bit Score: 58.79  E-value: 6.97e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209   44 EVVRINLSKCFPELseTELEKLVGQSLMDIGRTLTESACAWIWPpEKSLRYIREVEGMEVLEEAlaSGDGLVGITSHLGN 123
Cdd:PRK06628  51 KIARRNIKAVFGDM--CDVEKIIDQTWDNFGRFIGEFTYVNKMD-EAELERRIEIIGIENIKKL--EGQPFLLFSGHFAN 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209  124 WEV-LNHFYCSYAKPIIFYRPPKLKAVDELLKKQRVQLGNRVAPSTPEGILSVIKEVKKGGCVGIPADPEpaRTAGLFVP 202
Cdd:PRK06628 126 WDIsLKILHKFYPKVAVIYRKANNPYVNKLVNESRAGDKLRLIPKGPEGSRALVRAIKESESIVMLVDQK--MNDGIEVP 203

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209  203 YLGTTALISKFVPQLLSRGKARGVFFHAVRlPDGSGYKVILEA---------APADMYDKDLEVsvaamSRELAKYVRAY 273
Cdd:PRK06628 204 FLGHPAMTASAIAKIALQYKYPIIPCQIIR-TKGSYFKVIVHPqlkfeqtgdNKADCYNIMLNI-----NQMLGEWVKQN 277

                        250
                 ....*....|..
gi 15595209  274 PSQYMWSMKRFK 285
Cdd:PRK06628 278 PAQWFWFHNRWK 289
PRK05906 PRK05906
lipid A biosynthesis lauroyl acyltransferase; Provisional
 8-287 2.50e-07

lipid A biosynthesis lauroyl acyltransferase; Provisional


Pssm-ID: 168292 [Multi-domain]  Cd Length: 454  Bit Score: 51.71  E-value: 2.50e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209    8 LVVGALRLFALLPWRAVQGVGAGIGWLMWKLPNRSREVVRINLSKCFPELSETELEKLVGQSLMDIGRTLTESACAwiwp 87
Cdd:PRK05906  20 LGLGVITILRLLPRSSLRLFGKGLGTLLFYFISDYRKTALTNLALAFPEKSFAERYQIARQSVQHVIITFLELLAV---- 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209   88 pEKSLRYI------------------REVEGMEVLEEA---LASGDGLVGITSHLGNWEvLNHFYCS-------YAKPII 139
Cdd:PRK05906  96 -EKLAGHIdeliaiatsedapegffpEEVSSQQELEHTfsrLDEQEGAILFCGHQANWE-LPFLYITkrypglaFAKPIK 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209  140 FYR-PPKLKAVDELLKkqrvqlGNRVAPStpEGILSVIKEVKKGGCVGIPADpEPARTAGLFVPYLGTTALISKfVPQLL 218
Cdd:PRK05906 174 NRRlNKKIFSLRESFK------GKIVPPK--NGINQALRALHQGEVVGIVGD-QALLSSSYSYPLFGSQAFTTT-SPALL 243

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15595209  219 SRGKARGVFFHAV-RLPDgsGYKVILEAApadMY-DKDLEV--SVAA----MSRELAKYVRAYPSQYMWSMKRFKNR 287
Cdd:PRK05906 244 AYKTGKPVIAVAIyRKPN--GYLVVPSKK---FYaNKSLPIkeSTEQlmdrLMRFLEKGIACKPEQWMWLHKRWKRK 315
PRK07920 PRK07920
lipid A biosynthesis lauroyl acyltransferase; Provisional
 14-125 2.76e-07

lipid A biosynthesis lauroyl acyltransferase; Provisional


Pssm-ID: 236131 [Multi-domain]  Cd Length: 298  Bit Score: 51.09  E-value: 2.76e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595209   14 RLFALLPWRAVQGVGAGIGWLMWKLPNRSREVVRINLSKCFPELSETELEKLVGQSLMDIGRTLTESACAWIWPPEKSLR 93
Cdd:PRK07920   9 RLVRALPEPVARRLFDAGADVAWRRRGGGVRQLRRNLARVVPDAPAAVLDALVRAAMRSYARYWREAFRLPSMSRERLAA 88

                         90       100       110
                 ....*....|....*....|....*....|...
gi 15595209   94 YIR-EVEGMEVLEEALASGDGLVGITSHLGNWE 125
Cdd:PRK07920  89 RVRvSIEGLEHLDAALAAGRGVVLALPHSGNWD 121
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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