NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|15595311|ref|NP_248803|]
View 

protoheme IX farnesyltransferase [Pseudomonas aeruginosa PAO1]

Protein Classification

protoheme IX farnesyltransferase( domain architecture ID 10792362)

protoheme IX farnesyltransferase acts in step 1 of the conversion protoheme IX to heme O in heme O biosynthesis

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
PRK04375 PRK04375
protoheme IX farnesyltransferase; Provisional
4-303 1.15e-138

protoheme IX farnesyltransferase; Provisional


:

Pssm-ID: 235293  Cd Length: 296  Bit Score: 393.35  E-value: 1.15e-138
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311    4 VIDRHSQPTWRDFLELTKPKVVVLMLITSLIGMLLATKapldGFVPWQVLIFGNLGIGLCAGAAAAVNHVVDRRIDSIMA 83
Cdd:PRK04375   1 VSSSSSRATLKDYLALTKPRVISLNLFTALGGMLLAPP----GVPPLLLLLLTLLGIALVAGAAGALNNYIDRDIDAKME 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311   84 RTHKRPLAEGRVSPSMALGFALLLALAGMAVLLAFTNPLTAWLTLASLLGYAALYTGFLKRATPQNIVIGGLAGAAPPLL 163
Cdd:PRK04375  77 RTKNRPLVTGRISPREALIFGLVLGVLGFLLLGLFVNPLAAWLTLAGIFFYVVVYTLWLKRRTPQNIVIGGAAGAMPPLI 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311  164 GWVAITGHLSAEPLLLVLIIFAWTPPHFWALCIHRKDEYAKADIPMLPVTHGERYTKLHILLYTLVLFAVSLMPFVIHMS 243
Cdd:PRK04375 157 GWAAVTGSLSWEALILFLIIFLWTPPHFWALAIFRKDDYAAAGIPMLPVVKGIRVTKRQILLYTVLLVAVSLLPVLLGMA 236
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311  244 GLVYLLCALALGARFLDWAWALYCDSRPHAAIKTFKYSIVYLFLLFMALLVDHYLPLKLL 303
Cdd:PRK04375 237 GLLYLVVALLLGAWFLYYAWRLYRKDDRKWARKLFRYSINYLTLLFVALLVDHLLLLSLL 296
 
Name Accession Description Interval E-value
PRK04375 PRK04375
protoheme IX farnesyltransferase; Provisional
4-303 1.15e-138

protoheme IX farnesyltransferase; Provisional


Pssm-ID: 235293  Cd Length: 296  Bit Score: 393.35  E-value: 1.15e-138
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311    4 VIDRHSQPTWRDFLELTKPKVVVLMLITSLIGMLLATKapldGFVPWQVLIFGNLGIGLCAGAAAAVNHVVDRRIDSIMA 83
Cdd:PRK04375   1 VSSSSSRATLKDYLALTKPRVISLNLFTALGGMLLAPP----GVPPLLLLLLTLLGIALVAGAAGALNNYIDRDIDAKME 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311   84 RTHKRPLAEGRVSPSMALGFALLLALAGMAVLLAFTNPLTAWLTLASLLGYAALYTGFLKRATPQNIVIGGLAGAAPPLL 163
Cdd:PRK04375  77 RTKNRPLVTGRISPREALIFGLVLGVLGFLLLGLFVNPLAAWLTLAGIFFYVVVYTLWLKRRTPQNIVIGGAAGAMPPLI 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311  164 GWVAITGHLSAEPLLLVLIIFAWTPPHFWALCIHRKDEYAKADIPMLPVTHGERYTKLHILLYTLVLFAVSLMPFVIHMS 243
Cdd:PRK04375 157 GWAAVTGSLSWEALILFLIIFLWTPPHFWALAIFRKDDYAAAGIPMLPVVKGIRVTKRQILLYTVLLVAVSLLPVLLGMA 236
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311  244 GLVYLLCALALGARFLDWAWALYCDSRPHAAIKTFKYSIVYLFLLFMALLVDHYLPLKLL 303
Cdd:PRK04375 237 GLLYLVVALLLGAWFLYYAWRLYRKDDRKWARKLFRYSINYLTLLFVALLVDHLLLLSLL 296
CyoE COG0109
Polyprenyltransferase (heme O synthase) [Coenzyme transport and metabolism, Lipid transport ...
2-300 6.86e-126

Polyprenyltransferase (heme O synthase) [Coenzyme transport and metabolism, Lipid transport and metabolism];


Pssm-ID: 439879  Cd Length: 299  Bit Score: 361.37  E-value: 6.86e-126
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311   2 ATVIDRHSQPTWRDFLELTKPKVVVLMLITSLIGMLLATKapldGFVPWQVLIFGNLGIGLCAGAAAAVNHVVDRRIDSI 81
Cdd:COG0109   5 SASSAASLRSTLRDYLALTKPRIILLLLFTALAGMLLAAG----GLPDLLLLLLTLLGGALAAGAANALNNYIDRDIDAL 80
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311  82 MARTHKRPLAEGRVSPSMALGFALLLALAGMAVLLAFTNPLTAWLTLASLLGYAALYTGFLKRATPQNIVIGGLAGAAPP 161
Cdd:COG0109  81 MKRTKNRPLPTGRISPREALIFGLVLGVLGLALLALFVNPLAALLGLLGIFFYVVVYTLWLKRRTPQNIVIGGAAGAMPP 160
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311 162 LLGWVAITGHLSAEPLLLVLIIFAWTPPHFWALCIHRKDEYAKADIPMLPVTHGERYTKLHILLYTLVLFAVSLMPFVIH 241
Cdd:COG0109 161 LIGWAAVTGSLSLEALLLFLIIFLWTPPHFWALALKRRDDYARAGVPMLPVVKGERRTKRQILLYTLLLVPVSLLPYLLG 240
                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 15595311 242 MSGLVYLLCALALGARFLDWAWALYCDSRPHAAIKTFKYSIVYLFLLFMALLVDHYLPL 300
Cdd:COG0109 241 MAGLIYLVVALVLGAWFLYLAVRLYRRPDRKWARKLFKFSILYLTLLFLALLVDHLLLL 299
cyoE_ctaB TIGR01473
protoheme IX farnesyltransferase; This model describes protoheme IX farnesyltransferase, also ...
14-295 1.51e-107

protoheme IX farnesyltransferase; This model describes protoheme IX farnesyltransferase, also called heme O synthase, an enzyme that creates an intermediate in the biosynthesis of heme A. Prior to the description of its enzymatic function, this protein was often called a cytochrome o ubiquinol oxidase assembly factor. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin]


Pssm-ID: 273645  Cd Length: 280  Bit Score: 313.80  E-value: 1.51e-107
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311    14 RDFLELTKPKVVVLMLITSLIGMLLATKAPLdgfVPWQVLIFGNLGIGLCAGAAAAVNHVVDRRIDSIMARTHKRPLAEG 93
Cdd:TIGR01473   1 KDYLQLTKPRIISLLLITAFAGMWLAPGGAL---VNPPLLLLTLLGTTLAAASANAFNMYIDRDIDKKMKRTRNRPLVTG 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311    94 RVSPSMALGFALLLALAGMAVLLAFTNPLTAWLTLASLLGYAALYTGFLKRATPQNIVIGGLAGAAPPLLGWVAITGHLS 173
Cdd:TIGR01473  78 RISPREALAFGLLLGVLGVAILAAFVNPLAALLGLFGIFFYVIVYTIWLKRRTPQNTVIGGFAGAVPPLIGWAAVTGSIS 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311   174 AEPLLLVLIIFAWTPPHFWALCIHRKDEYAKADIPMLPVTHGERYTKLHILLYTLVLFAVSLMPFVIHMSGLVYLLCALA 253
Cdd:TIGR01473 158 LGAWLLFAIIFLWQPPHFWALALKYKDDYRAAGIPMLPVVKGERITKRQIALYTAALLPVSLLLAFLGGTGWLYLIVATL 237
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 15595311   254 LGARFLDWAWALYCDSRPHA-AIKTFKYSIVYLFLLFMALLVD 295
Cdd:TIGR01473 238 LGALFLYLAFKFYRDPTDRKkARKLFKFSLIYLALLFVALLID 280
PT_UbiA_Cox10 cd13957
Protoheme IX farnesyltransferase; Protoheme IX farnesyltransferase (also called heme O ...
17-291 2.65e-103

Protoheme IX farnesyltransferase; Protoheme IX farnesyltransferase (also called heme O synthase, heme A:farnesyltransferase, cytochrome c oxidase subunit X [Cox10]) converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of the heme B porphyrin ring with a hydroxyethyl farnesyl side group. It is localized at the mitochondrial inner membrane. Eukaryotic Cox10 is important for the maturation of the heme A prosthetic group of cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, that catalyzes the electron transfer from reduced cytochrome c to oxygen. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260120  Cd Length: 271  Bit Score: 302.82  E-value: 2.65e-103
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311  17 LELTKPKVVVLMLITSLIGMLLATKapldGFVPWQVLIFGNLGIGLCAGAAAAVNHVVDRRIDSIMARTHKRPLAEGRVS 96
Cdd:cd13957   1 LELTKPRITLLVLLTALAGYLLAPG----GVPDLLLLLLTLLGTALVSASANALNQYIERDIDAKMKRTRNRPLPSGRIS 76
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311  97 PSMALGFALLLALAGMAVLLAFTNPLTAWLTLASLLGYAALYTGFLKRATPQNIVIGGLAGAAPPLLGWVAITGHLSAEP 176
Cdd:cd13957  77 PKHALIFGLVLGILGLALLALFVNPLTALLGLLGIFLYVFVYTPLKKRTTPLNTVIGGIAGAIPPLIGWAAATGSLDLGA 156
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311 177 LLLVLIIFAWTPPHFWALCIHRKDEYAKADIPMLPVTHGERYTKLHILLYTLVLFAVSLMPFVIHMSGLVYLLCALALGA 256
Cdd:cd13957 157 WLLFLILFLWQPPHFWALAILYRDDYARAGIPMLPVVKGERRTKRQILLYTLLLVPLSLLLYLLGLTGWIYLVVALLLGL 236
                       250       260       270
                ....*....|....*....|....*....|....*
gi 15595311 257 RFLDWAWALYCDSRPHAAIKTFKYSIVYLFLLFMA 291
Cdd:cd13957 237 YFLYLAIKLYRSPDDKWARKLFFASLIYLPLLFLL 271
UbiA pfam01040
UbiA prenyltransferase family;
28-278 2.42e-45

UbiA prenyltransferase family;


Pssm-ID: 460038 [Multi-domain]  Cd Length: 250  Bit Score: 153.92  E-value: 2.42e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311    28 MLITSLIGMLLATkaplDGFVPWQVLIFGNLGIGLCAGAAAAVNHVVDRRIDSIMARTHKRPLAEGRVSPSMALGFALLL 107
Cdd:pfam01040   1 LLIPALAGLALAA----GGVPDLLLLLLALLGTVLARAAANALNDYYDRDIDAIMPRTPNRPLPSGRISPREALIFALVL 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311   108 ALAGMAVLLaFTNPLTAWLTLASLLGYAaLYTGFLKRATPQNIVIGGLAGAAPPLLGWVAITGHLSAEPLLLVLIIFAWT 187
Cdd:pfam01040  77 LALGLLLLL-LLNPLTALLGLAALLLYV-LYTLRLKRRTLLGQLVGGLAFGLPPLLGWAAVTGSLSPLALLLALALFLWT 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311   188 PPHFWALCIHRKDEYAKADIPMLPVTHGERYTKLHILLYTLVLFAVsLMPFVIHMSGLVYLLCALALGARFLDWAWALYC 267
Cdd:pfam01040 155 WAIALANDLRDREDDRKAGIKTLPVVLGRKAARILLALLLAVALLL-LLLLLLLLLGGLYLLLALLLAALALLYAARLLR 233
                         250
                  ....*....|.
gi 15595311   268 DSRPHAAIKTF 278
Cdd:pfam01040 234 LRDPKKDAKAF 244
 
Name Accession Description Interval E-value
PRK04375 PRK04375
protoheme IX farnesyltransferase; Provisional
4-303 1.15e-138

protoheme IX farnesyltransferase; Provisional


Pssm-ID: 235293  Cd Length: 296  Bit Score: 393.35  E-value: 1.15e-138
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311    4 VIDRHSQPTWRDFLELTKPKVVVLMLITSLIGMLLATKapldGFVPWQVLIFGNLGIGLCAGAAAAVNHVVDRRIDSIMA 83
Cdd:PRK04375   1 VSSSSSRATLKDYLALTKPRVISLNLFTALGGMLLAPP----GVPPLLLLLLTLLGIALVAGAAGALNNYIDRDIDAKME 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311   84 RTHKRPLAEGRVSPSMALGFALLLALAGMAVLLAFTNPLTAWLTLASLLGYAALYTGFLKRATPQNIVIGGLAGAAPPLL 163
Cdd:PRK04375  77 RTKNRPLVTGRISPREALIFGLVLGVLGFLLLGLFVNPLAAWLTLAGIFFYVVVYTLWLKRRTPQNIVIGGAAGAMPPLI 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311  164 GWVAITGHLSAEPLLLVLIIFAWTPPHFWALCIHRKDEYAKADIPMLPVTHGERYTKLHILLYTLVLFAVSLMPFVIHMS 243
Cdd:PRK04375 157 GWAAVTGSLSWEALILFLIIFLWTPPHFWALAIFRKDDYAAAGIPMLPVVKGIRVTKRQILLYTVLLVAVSLLPVLLGMA 236
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311  244 GLVYLLCALALGARFLDWAWALYCDSRPHAAIKTFKYSIVYLFLLFMALLVDHYLPLKLL 303
Cdd:PRK04375 237 GLLYLVVALLLGAWFLYYAWRLYRKDDRKWARKLFRYSINYLTLLFVALLVDHLLLLSLL 296
CyoE COG0109
Polyprenyltransferase (heme O synthase) [Coenzyme transport and metabolism, Lipid transport ...
2-300 6.86e-126

Polyprenyltransferase (heme O synthase) [Coenzyme transport and metabolism, Lipid transport and metabolism];


Pssm-ID: 439879  Cd Length: 299  Bit Score: 361.37  E-value: 6.86e-126
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311   2 ATVIDRHSQPTWRDFLELTKPKVVVLMLITSLIGMLLATKapldGFVPWQVLIFGNLGIGLCAGAAAAVNHVVDRRIDSI 81
Cdd:COG0109   5 SASSAASLRSTLRDYLALTKPRIILLLLFTALAGMLLAAG----GLPDLLLLLLTLLGGALAAGAANALNNYIDRDIDAL 80
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311  82 MARTHKRPLAEGRVSPSMALGFALLLALAGMAVLLAFTNPLTAWLTLASLLGYAALYTGFLKRATPQNIVIGGLAGAAPP 161
Cdd:COG0109  81 MKRTKNRPLPTGRISPREALIFGLVLGVLGLALLALFVNPLAALLGLLGIFFYVVVYTLWLKRRTPQNIVIGGAAGAMPP 160
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311 162 LLGWVAITGHLSAEPLLLVLIIFAWTPPHFWALCIHRKDEYAKADIPMLPVTHGERYTKLHILLYTLVLFAVSLMPFVIH 241
Cdd:COG0109 161 LIGWAAVTGSLSLEALLLFLIIFLWTPPHFWALALKRRDDYARAGVPMLPVVKGERRTKRQILLYTLLLVPVSLLPYLLG 240
                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 15595311 242 MSGLVYLLCALALGARFLDWAWALYCDSRPHAAIKTFKYSIVYLFLLFMALLVDHYLPL 300
Cdd:COG0109 241 MAGLIYLVVALVLGAWFLYLAVRLYRRPDRKWARKLFKFSILYLTLLFLALLVDHLLLL 299
cyoE_ctaB TIGR01473
protoheme IX farnesyltransferase; This model describes protoheme IX farnesyltransferase, also ...
14-295 1.51e-107

protoheme IX farnesyltransferase; This model describes protoheme IX farnesyltransferase, also called heme O synthase, an enzyme that creates an intermediate in the biosynthesis of heme A. Prior to the description of its enzymatic function, this protein was often called a cytochrome o ubiquinol oxidase assembly factor. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin]


Pssm-ID: 273645  Cd Length: 280  Bit Score: 313.80  E-value: 1.51e-107
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311    14 RDFLELTKPKVVVLMLITSLIGMLLATKAPLdgfVPWQVLIFGNLGIGLCAGAAAAVNHVVDRRIDSIMARTHKRPLAEG 93
Cdd:TIGR01473   1 KDYLQLTKPRIISLLLITAFAGMWLAPGGAL---VNPPLLLLTLLGTTLAAASANAFNMYIDRDIDKKMKRTRNRPLVTG 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311    94 RVSPSMALGFALLLALAGMAVLLAFTNPLTAWLTLASLLGYAALYTGFLKRATPQNIVIGGLAGAAPPLLGWVAITGHLS 173
Cdd:TIGR01473  78 RISPREALAFGLLLGVLGVAILAAFVNPLAALLGLFGIFFYVIVYTIWLKRRTPQNTVIGGFAGAVPPLIGWAAVTGSIS 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311   174 AEPLLLVLIIFAWTPPHFWALCIHRKDEYAKADIPMLPVTHGERYTKLHILLYTLVLFAVSLMPFVIHMSGLVYLLCALA 253
Cdd:TIGR01473 158 LGAWLLFAIIFLWQPPHFWALALKYKDDYRAAGIPMLPVVKGERITKRQIALYTAALLPVSLLLAFLGGTGWLYLIVATL 237
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 15595311   254 LGARFLDWAWALYCDSRPHA-AIKTFKYSIVYLFLLFMALLVD 295
Cdd:TIGR01473 238 LGALFLYLAFKFYRDPTDRKkARKLFKFSLIYLALLFVALLID 280
PT_UbiA_Cox10 cd13957
Protoheme IX farnesyltransferase; Protoheme IX farnesyltransferase (also called heme O ...
17-291 2.65e-103

Protoheme IX farnesyltransferase; Protoheme IX farnesyltransferase (also called heme O synthase, heme A:farnesyltransferase, cytochrome c oxidase subunit X [Cox10]) converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of the heme B porphyrin ring with a hydroxyethyl farnesyl side group. It is localized at the mitochondrial inner membrane. Eukaryotic Cox10 is important for the maturation of the heme A prosthetic group of cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, that catalyzes the electron transfer from reduced cytochrome c to oxygen. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260120  Cd Length: 271  Bit Score: 302.82  E-value: 2.65e-103
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311  17 LELTKPKVVVLMLITSLIGMLLATKapldGFVPWQVLIFGNLGIGLCAGAAAAVNHVVDRRIDSIMARTHKRPLAEGRVS 96
Cdd:cd13957   1 LELTKPRITLLVLLTALAGYLLAPG----GVPDLLLLLLTLLGTALVSASANALNQYIERDIDAKMKRTRNRPLPSGRIS 76
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311  97 PSMALGFALLLALAGMAVLLAFTNPLTAWLTLASLLGYAALYTGFLKRATPQNIVIGGLAGAAPPLLGWVAITGHLSAEP 176
Cdd:cd13957  77 PKHALIFGLVLGILGLALLALFVNPLTALLGLLGIFLYVFVYTPLKKRTTPLNTVIGGIAGAIPPLIGWAAATGSLDLGA 156
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311 177 LLLVLIIFAWTPPHFWALCIHRKDEYAKADIPMLPVTHGERYTKLHILLYTLVLFAVSLMPFVIHMSGLVYLLCALALGA 256
Cdd:cd13957 157 WLLFLILFLWQPPHFWALAILYRDDYARAGIPMLPVVKGERRTKRQILLYTLLLVPLSLLLYLLGLTGWIYLVVALLLGL 236
                       250       260       270
                ....*....|....*....|....*....|....*
gi 15595311 257 RFLDWAWALYCDSRPHAAIKTFKYSIVYLFLLFMA 291
Cdd:cd13957 237 YFLYLAIKLYRSPDDKWARKLFFASLIYLPLLFLL 271
UbiA pfam01040
UbiA prenyltransferase family;
28-278 2.42e-45

UbiA prenyltransferase family;


Pssm-ID: 460038 [Multi-domain]  Cd Length: 250  Bit Score: 153.92  E-value: 2.42e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311    28 MLITSLIGMLLATkaplDGFVPWQVLIFGNLGIGLCAGAAAAVNHVVDRRIDSIMARTHKRPLAEGRVSPSMALGFALLL 107
Cdd:pfam01040   1 LLIPALAGLALAA----GGVPDLLLLLLALLGTVLARAAANALNDYYDRDIDAIMPRTPNRPLPSGRISPREALIFALVL 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311   108 ALAGMAVLLaFTNPLTAWLTLASLLGYAaLYTGFLKRATPQNIVIGGLAGAAPPLLGWVAITGHLSAEPLLLVLIIFAWT 187
Cdd:pfam01040  77 LALGLLLLL-LLNPLTALLGLAALLLYV-LYTLRLKRRTLLGQLVGGLAFGLPPLLGWAAVTGSLSPLALLLALALFLWT 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311   188 PPHFWALCIHRKDEYAKADIPMLPVTHGERYTKLHILLYTLVLFAVsLMPFVIHMSGLVYLLCALALGARFLDWAWALYC 267
Cdd:pfam01040 155 WAIALANDLRDREDDRKAGIKTLPVVLGRKAARILLALLLAVALLL-LLLLLLLLLGGLYLLLALLLAALALLYAARLLR 233
                         250
                  ....*....|.
gi 15595311   268 DSRPHAAIKTF 278
Cdd:pfam01040 234 LRDPKKDAKAF 244
PLN02776 PLN02776
prenyltransferase
19-299 1.06e-38

prenyltransferase


Pssm-ID: 215415  Cd Length: 341  Bit Score: 139.11  E-value: 1.06e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311   19 LTKPKVVVLMLITSLIGMLLATKAPLDgfvpWQVLIFGNLGIGLCAGAAAAVNHVVDRRIDSIMARTHKRPLAEGRVSPS 98
Cdd:PLN02776   1 LSKARLSALVVATSGAGFVLGSGEAID----LPGLGWTCAGTMLCAASANTLNQVFEVKNDSKMKRTMRRPLPSGRISVP 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311   99 MALGFALLLALAGMAVLLAFTNPLTAWLTLASLLGYAALYTgFLKRATPQNIVIGGLAGAAPPLLGWVAITGHLSAEPLL 178
Cdd:PLN02776  77 HAVAWAVVVGAAGVALLAYKTNMLTAGLGAGNILLYAFVYT-PLKQIHPANTWVGAVVGAIPPLMGWAAASGQLDAGAMV 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311  179 LVLIIFAWTPPHFWALCIHRKDEYAKADIPMLPVTHGE-RYTKLHILLYTLVLFAVslmPFVIHMSGLV---YLLCALAL 254
Cdd:PLN02776 156 LAAALYFWQMPHFMALAYMCRDDYAAGGYRMLSLADATgRRTALVALRNCLYLAPL---GFLAYDWGVTsspFALEAALL 232
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 15595311  255 GARFLDWAWALYCDSRPHAAIKTFKYSIVYLfLLFMALLVDHYLP 299
Cdd:PLN02776 233 TAYLAASAASFYREPTNANARKMFHGSLLYL-PAFMALLLLHRVP 276
UbiA COG0382
4-hydroxybenzoate polyprenyltransferase [Coenzyme transport and metabolism]; 4-hydroxybenzoate ...
14-294 1.03e-18

4-hydroxybenzoate polyprenyltransferase [Coenzyme transport and metabolism]; 4-hydroxybenzoate polyprenyltransferase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440151  Cd Length: 280  Bit Score: 84.13  E-value: 1.03e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311  14 RDFLELT---KPKVVVLMLITSLIGMLLATkaplDGFVPWQVLIFGNLGIGLCAGAAAAVNHVVDRRIDSIMARTHKRPL 90
Cdd:COG0382   1 RAYLRLLrldRPIGILLLLWPTLWALFLAA----GGLPDLLLLLLAVLGTVLMRSAGYVINDYFDREIDRINERKPNRPL 76
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311  91 AEGRVSPsMALGFALLLALAGMAVLLAFTNPLTAWLTLASLLGyAALYTGFLKRATPQNIVIGGLAGAAPPLLGWVAITG 170
Cdd:COG0382  77 ASGRISL-REALLLAIVLLLLALALALLLNPLTFLLALAALAL-AWAYSLFLKRFTLLGNLVLGLLFGLGILMGFAAVTG 154
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311 171 HLSAEPLLLVLIIFAWTpphfWALCI----HRKDEYAKADIPMLPVTHGERYTKLHILLYTLVLFAVSLMPFVIHMSGLV 246
Cdd:COG0382 155 SLPLSAWLLALAAFLWT----LAYDTiydlEDREGDRKIGIKTLAILFGVRDALIIAGVLYALAVLLLLLLGLLAGLGLL 230
                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|
gi 15595311 247 YLLCALALGARFLDWAWALYCDSR--PHAAIKTFKYSIVYLFLLFMALLV 294
Cdd:COG0382 231 YLLGLLAALLLLYLSQLWLLRPRKkdPARALKLFKLNMLLGLLLFLGIAL 280
PT_UbiA_COQ2 cd13959
4-Hydroxybenzoate polyprenyltransferase; 4-Hydroxybenzoate polyprenyltransferase, also known ...
17-295 8.63e-17

4-Hydroxybenzoate polyprenyltransferase; 4-Hydroxybenzoate polyprenyltransferase, also known as Coq2, catalyzes the prenylation of p-hydroxybenzoate with an all-trans polyprenyl group, an important step in ubiquinone (CoQ) biosynthesis. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260122 [Multi-domain]  Cd Length: 272  Bit Score: 78.28  E-value: 8.63e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311  17 LELTKPKVVVLMLITSLIGMLLATkAPLDGFVPWQVLIFGnLGIGLCAGAAAAVNHVVDRRIDSIMARTHKRPLAEGRVS 96
Cdd:cd13959   1 MRLDKPIGTLLLLPPALWGLLLAA-GGLPLPLLKLLLLFL-LGAFLMRSAGCTINDIADRDIDAKVPRTKNRPLASGAIS 78
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311  97 PSmALGFALLLALAGMAVLLAFTNPLTAWLTLASLLGyAALYTgFLKRAT--PQniVIGGLAGAAPPLLGWVAITGHLSA 174
Cdd:cd13959  79 VK-EALLFLAVQLLLGLALLLQLNPLTILLSPIALLL-VLIYP-LMKRFTywPQ--LVLGLAFGWGPLMGWAAVTGSLPL 153
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311 175 EPLLLVLIIFAWTpphfwalcIHRKDEYAKADIP--------MLPVTHGERyTKLHILLYTLVLFAVSLMPFVIHMSGLV 246
Cdd:cd13959 154 PALLLYLAVIFWT--------AGYDTIYAHQDREddrkigvkSTAVLFGDR-TKLILALLLHLFVALLLLAGGLAGLGWP 224
                       250       260       270       280
                ....*....|....*....|....*....|....*....|....*....
gi 15595311 247 YLLcALALGARFLDWAWALYCDSRPHAAIKTFKYSIVYLFLLFMALLVD 295
Cdd:cd13959 225 YYL-GLGAAAHLLWQEHRLDLPDPLRSCLAFFLSNGWVGLLLFAGLLLD 272
PT_UbiA cd13956
UbiA family of prenyltransferases (PTases); Many characterized members of the UbiA ...
17-294 6.84e-14

UbiA family of prenyltransferases (PTases); Many characterized members of the UbiA prenyltransferase family are aromatic prenyltransferases and play an important role in the biosynthesis of heme, chlorophyll, vitamin E, and vitamin K. They contain two copies of a motif similar to the active site DxxD motif of trans-prenyltransferases and are potentially related. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260119 [Multi-domain]  Cd Length: 271  Bit Score: 70.07  E-value: 6.84e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311  17 LELTKPKVVVLMLITSLIGMLLATKAPLDGFVPWQVLIFGnlgIGLCAGAAAAVNHVVDRRIDSImaRTHKRPLAEGRVS 96
Cdd:cd13956   1 LRLMRPYTLLYVLAPALAGAALAGAFAGPLPALLLLALLA---VFLGAGAGYALNDYTDRELDAI--NKPDRPLPSGRLS 75
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311  97 PSMALGFALLLALAGmaVLLAFT-NPLTAWLTLASLLGyAALYTGFLKR-ATPQNIVIGGLAGAAPPLLGWVAITGHLSA 174
Cdd:cd13956  76 PRQALAFAAALLLVG--LALALAlGPLALLLLLAGLLL-GLAYSLGLKRlKLGGWGVLGYATGLALLPGLGAVAAGGLVP 152
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311 175 EPLLLVLIIFAWTPPHFWALCIHRKDEYAKADIPMLPVTHGERYTKLHILLYTLVLFAVSLMPFVIHMSGLVYLLCALAL 254
Cdd:cd13956 153 LALLLALVFLLLGLGINLYNDLPDVEGDRAAGIRTLPVRLGPRRARRLAAGLLLAALILVVLLAVAGLLGPLALLALLAV 232
                       250       260       270       280
                ....*....|....*....|....*....|....*....|
gi 15595311 255 GARFLdWAWALYCDSRPHAAIKTFKYSIVYLFLLFMALLV 294
Cdd:cd13956 233 ALLAL-RARFARADRLPALPRGFLLLAVYRLLLFAALLLA 271
ubiA PRK12882
prenyltransferase; Reviewed
12-294 2.02e-07

prenyltransferase; Reviewed


Pssm-ID: 183811  Cd Length: 276  Bit Score: 51.13  E-value: 2.02e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311   12 TWRDFLELTKPKVVVLMLITSLIGMLLATKAPLDGFVPwqVLIFgnLGIGLCAGAAAAVNHVVDRRIDSImaRTHKRPLA 91
Cdd:PRK12882   3 TVRGYLELTRPVNAVVAGVAAFIGAFIAGGILSSPSLT--GLAF--AAVFLATGAGNAINDYFDREIDRI--NRPDRPIP 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311   92 EGRVSPSMALGFALLLALAGMAVLLaFTNPLTAWLTLASLLGYAaLYTGFLKRaTP--QNIVIGGLAGAAppLLGWVAIT 169
Cdd:PRK12882  77 SGAVSPRGALAFSILLFAAGVALAF-LLPPLCLAIALFNSLLLV-LYAETLKG-TPglGNASVAYLTGST--FLFGGAAV 151
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311  170 GhlsAEPLLLVLIIFAWTpphfWALCIHRK----------DEYAKADipMLPVTHGERYTKLHILLYTLVLFAVSLMPFV 239
Cdd:PRK12882 152 G---TEGLLALLVLFALA----ALATLAREiikdvediegDRAEGAR--TLPILIGVRKALYVAAAFLLVAVAASPLPYL 222
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 15595311  240 IHMSGLVYLLCALALGARFLDWAWALYCDSRPHAAIKTFKYSivylflLFMALLV 294
Cdd:PRK12882 223 LSTFGLWYLVLVAPADLVMLAAAYRSLKKTDPTASQKLLKYG------MFLALAA 271
PT_UbiA_DGGGPS cd13961
Geranylgeranylglycerol-phosphate geranylgeranyltransferase; Digeranylgeranylglyceryl phosphate ...
16-290 3.12e-07

Geranylgeranylglycerol-phosphate geranylgeranyltransferase; Digeranylgeranylglyceryl phosphate synthase (DGGGPS) transfers a geranylgeranyl group from geranylgeranyl diphosphate to (S)-3-O-geranylgeranylglyceryl phosphate to form (S)-2,3-di-O-geranylgeranylglyceryl phosphate, as part of the isoprenoid ether lipid biosynthesis. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260124  Cd Length: 270  Bit Score: 50.58  E-value: 3.12e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311  16 FLELTKPKVVVLMLITSLIGMLLATkaPLDGFVPWQVLIFGNLGIGLCAGAAAAVNHVVDRRIDSIMARthKRPLAEGRV 95
Cdd:cd13961   2 YLELIRPPNLLMAALAQYLGALFAL--GPLLSLNDLELLLLFLSVFLIAAAGYIINDYFDVEIDRINKP--DRPIPSGRI 77
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311  96 SPSMALGFALLLALAGMAVLLAFTNPLTAWLTLASLLGYaaLYTGFLKRAT-PQNIVIGGLAGAaPPLLGWVAitghlsA 174
Cdd:cd13961  78 SRREALILSILLNALGLILAFLLSPLALLIALLNSLLLW--LYSHKLKRTPlIGNLLVALLTGL-PFLFGGLA------A 148
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311 175 EPLLLVLIIFAwtpphFWALCIH--R---KDEY-----AKADIPMLPVTHGERYTKLHILLYTLVLFAVSLMPFVIHMSG 244
Cdd:cd13961 149 GNLLLIILLLA-----LFAFLITlgReivKDIEdvegdRAEGARTLPIVYGIKKAKKIAALLLLLAILLSPLPYLLGGLG 223
                       250       260       270       280
                ....*....|....*....|....*....|....*....|....*..
gi 15595311 245 LVYLLCALALGARFLDWA-WALYCDSRPHAAIKTFKYSIVYLFLLFM 290
Cdd:cd13961 224 ILYLILIIIADLLFLYSAiRLAKSPKDYSKLSKLLKLAMLLGLLAFL 270
ubiA PRK12884
prenyltransferase; Reviewed
14-294 4.28e-07

prenyltransferase; Reviewed


Pssm-ID: 183812  Cd Length: 279  Bit Score: 50.34  E-value: 4.28e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311   14 RDFLELTKPKVVVLMLITSLIGMLLAtkaplDGFVPWQVLIFGNLGIGLCAGAAAAVNHVVDRRIDSIMARThkRPLAEG 93
Cdd:PRK12884   5 KAYLELLRPEHGLMAGIAVVLGAIIA-----LGGLPLDEALLGFLTAFFASGSANALNDYFDYEVDRINRPD--RPIPSG 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311   94 RVSpSMALGFALLLALAGMAVLLAFTNPLtAWLTLASLLGYAALYTGFLKRA-TPQNIVIGGLAGaAPPLLGWVAItGHL 172
Cdd:PRK12884  78 RIS-RREALLLAILLFILGLIAAYLISPL-AFLVVILVSVLGILYNWKLKEYgLIGNLYVAFLTG-MTFIFGGIAV-GEL 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311  173 SAEPLLLVLIIFAWTPPHFWALCIHRKDEYAKADIPMLPVTHGERYT-KLHILLYTLVLfAVSLMPFVIHMSGLVYLLCA 251
Cdd:PRK12884 154 NEAVILLAAMAFLMTLGREIMKDIEDVEGDRLRGARTLAILYGEKIAgRIAAALFILAV-LLSPLPYLFGIFNILYLAPV 232
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 15595311  252 LALGARFLDWAWALYCDSRPHAAIKTFKYSIVYLFLLFMALLV 294
Cdd:PRK12884 233 LVADLIFLYSAYSLLRSQDRETIRKVRKITLTAMLLALVAFAL 275
ubiA PRK12888
4-hydroxybenzoate octaprenyltransferase;
14-186 2.49e-06

4-hydroxybenzoate octaprenyltransferase;


Pssm-ID: 183814  Cd Length: 284  Bit Score: 48.18  E-value: 2.49e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311   14 RDFLELTKPKVVVLMLITSLIGMLLATKApLDGFVPWQVLIFGNLGIGLCAGAAAAVNHVVDRRIDSIMARTHKRPLAEG 93
Cdd:PRK12888   3 RAFLRLVAIEHSVFALPFAYIAALTAMFA-SDGSVHWADLLLVTVAMVGARTFAMAANRIIDREIDARNPRTAGRELVTG 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311   94 RVSPSMALGFALLLALAGMAVLLAFtNPLT---AWLTLASLLGYAalytgFLKRATPQNIVIGGLAGAAPPLLGWVAITG 170
Cdd:PRK12888  82 AVSVRTAWTGALVALAVFLGAAALL-NPLClalAPLAVAPLVVYP-----YAKRFTNFPHAILGLAQAVGPVGAWIAVTG 155
                        170
                 ....*....|....*.
gi 15595311  171 HLSAEPLLLVLIIFAW 186
Cdd:PRK12888 156 TWSWPAVLLGLAVGLW 171
ubiA PRK12874
4-hydroxybenzoate polyprenyltransferase;
14-187 2.57e-06

4-hydroxybenzoate polyprenyltransferase;


Pssm-ID: 237242  Cd Length: 291  Bit Score: 48.08  E-value: 2.57e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311   14 RDFLELTKPKVVVLMLITSLIGMLLATKAPLD-GFVPWQVLIfgnLGIGLCAGA---AAAVNHVVDRRIDSIMARTHKRP 89
Cdd:PRK12874   9 KDISELVVFKHSIFSLPFIFIAMIVASKQKNDtGWFGFKLLI---LGILAAVSArnfAMAFNRLVDRDIDKDNPRTANRP 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311   90 LAEGRVSPSmALGFALLLALAGMAVLLAFTNPLTAWLTLAsLLGYAALYTGFlKRATPQNIVIGGLAGAAPPLLGWVAIT 169
Cdd:PRK12874  86 SVDGRISVK-SMVLFIVLNALIFIGVSYFINPLAFKLSFP-FLIVLGGYSYF-KRFSSLAHLVLGLSLGLAPIAGVVAVL 162
                        170
                 ....*....|....*...
gi 15595311  170 GHLSAEPLLLVLIIFAWT 187
Cdd:PRK12874 163 GEIPLWSVFLALGVMFWV 180
ubiA PRK12886
prenyltransferase; Reviewed
66-186 1.23e-05

prenyltransferase; Reviewed


Pssm-ID: 237247  Cd Length: 291  Bit Score: 45.84  E-value: 1.23e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311   66 AAAAVNHVVDRRIDSIMARTHKRPLAEGRVSpSMALGFALLLALAGMAVLLAFTNPLTAWL---TLASLLGYAalytgFL 142
Cdd:PRK12886  57 AAMGFNRLIDAEIDARNPRTAGRAIPAGLIS-KGSAILFIVLSSLLMLFAAWFLNPLCLYLsppALFFLLLYS-----YC 130
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 15595311  143 KRATPQNIVIGGLAGAAPPLLGWVAITGHLSAEPLLLVLIIFAW 186
Cdd:PRK12886 131 KRFTALAHVVLGFCLALAPLGAWIAIRGTIELPAILLGLAVLFW 174
PRK09573 PRK09573
(S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase; Reviewed
16-294 1.03e-03

(S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase; Reviewed


Pssm-ID: 181963  Cd Length: 279  Bit Score: 39.94  E-value: 1.03e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311   16 FLELTKPKVVVLMLITSLIGMLLATKAPLDgfvpWQVLIFGNLGIGLCAGAAAAVNHVVDRRIDSImaRTHKRPLAEGRV 95
Cdd:PRK09573   6 YFELIRPKNCIGASIGAIIGYLIASNFKID----LKGIILAALVVFLVCAGGNVINDIYDIEIDKI--NKPERPIPSGRI 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311   96 SPSMALGFALLLALA--GMAVLLAFTNPLTAWLTLASLLGYAALYTgflKRATPQNIVIGGLAGAappllgwVAITGHLS 173
Cdd:PRK09573  80 SLKEAKIFSITLFIVglILSIFINIYAFLIALLNSILLYLYAKDLK---KTGLIGNLIVAYLTGL-------SFIFGGLA 149
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311  174 AEPLLLVLIIFAWTPPHFWALCIHRKDEYAKADIP----MLPVTHGERYTKLHILLYTLVLFAVSLMPFVIHMSGLVYLL 249
Cdd:PRK09573 150 VFNVLRIIILFLCAFFSTWSREIVKDIEDIEGDLKenviTLPIKYGIKKSWYIAKILLILAIVLSPLPYFLGIFGIYYLI 229
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 15595311  250 CALALGARFLDWAWALYCDSRPHAAIKTFKYSIVYLFLLFMALLV 294
Cdd:PRK09573 230 VVIICDILFIIAMLILLKNPSIEGASKASKYLKIIMILGLIAFLI 274
PLN02809 PLN02809
4-hydroxybenzoate nonaprenyltransferase
54-98 4.01e-03

4-hydroxybenzoate nonaprenyltransferase


Pssm-ID: 178405  Cd Length: 289  Bit Score: 38.13  E-value: 4.01e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 15595311   54 IFGnLGIGLCAGAAAAVNHVVDRRIDSIMARTHKRPLAEGRVSPS 98
Cdd:PLN02809  49 LFG-CGALLLRGAGCTINDLLDRDIDKKVERTKLRPIASGALTPF 92
ubiA PRK12873
4-hydroxybenzoate polyprenyltransferase;
7-98 5.93e-03

4-hydroxybenzoate polyprenyltransferase;


Pssm-ID: 171787 [Multi-domain]  Cd Length: 294  Bit Score: 37.72  E-value: 5.93e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595311    7 RHSQPTWRDFLEL---TKPKVVVLMLITSLIGMLLATKAPLDGFVPWQVLIfGNLgigLCAGAAAAVNHVVDRRIDSIMA 83
Cdd:PRK12873   1 KSRSIKLSPWFELlrwNKPTGRLILLIPAGWSLWLTPSAPPSLLLLLLIIL-GGL---AVSGAGCIANDLWDRRIDRKVE 76
                         90
                 ....*....|....*
gi 15595311   84 RTHKRPLAEGRVSPS 98
Cdd:PRK12873  77 RTKNRPLARGKISLK 91
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH