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Conserved domains on  [gi|15595421|ref|NP_248915|]
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class II aldolase/adducin domain-containing protein [Pseudomonas aeruginosa PAO1]

Protein Classification

class II aldolase/adducin family protein( domain architecture ID 10012880)

class II aldolase/adducin family protein similar to L-fuculose phosphate aldolase, which catalyzes the reversible aldol cleavage of L-fuculose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK07090 PRK07090
class II aldolase/adducin domain protein; Provisional
 1-260 0e+00

class II aldolase/adducin domain protein; Provisional


:

Pssm-ID: 180832  Cd Length: 260  Bit Score: 549.62  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421    1 MATTLELPKDQLIQHALKQMKSSLGDNTWTDRQKLALTCRILFEAGHDSGLAGQITSRGPEAGTYYTQQLGLGFDEISAG 80
Cdd:PRK07090   1 MAKTLSLSKDELVARAQRQMDNELKDSGWTLRQKLALTCRILFDAGHDSGLAGQITARAEAPGTYYTQRLGLGFDEITAS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421   81 NLLLVDEDLNVLHGHGMANPANRFHSWVYRARPDVNCIIHTHPLHIAALSTLEVPLQVSHMDLCPLYDDCAFLKDWPGVP 160
Cdd:PRK07090  81 NLLLVDEDLNVLDGEGMPNPANRFHSWIYRARPDVNCIIHTHPPHVAALSMLEVPLVVSHMDTCPLYDDCAFLKDWPGVP 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421  161 VGNEEGEIISAALGDKRAILLSHHGLLATGASIEEACVIAVLLERAAKMQLLAMAAGEIKPIPPALAREAHDWISTPKRH 240
Cdd:PRK07090 161 VGNEEGEIISAALGDKRAILLSHHGQLVAGKSIEEACVLALLIERAARLQLLAMAAGPIKPIPPELAREAHDWISTPKRS 240

                        250       260
                 ....*....|....*....|
gi 15595421  241 GAAFNYYARRCLPRNSDCLS 260
Cdd:PRK07090 241 AATFAYYARRALRRHPDCLD 260
 
Name Accession Description Interval E-value
PRK07090 PRK07090
class II aldolase/adducin domain protein; Provisional
 1-260 0e+00

class II aldolase/adducin domain protein; Provisional


Pssm-ID: 180832  Cd Length: 260  Bit Score: 549.62  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421    1 MATTLELPKDQLIQHALKQMKSSLGDNTWTDRQKLALTCRILFEAGHDSGLAGQITSRGPEAGTYYTQQLGLGFDEISAG 80
Cdd:PRK07090   1 MAKTLSLSKDELVARAQRQMDNELKDSGWTLRQKLALTCRILFDAGHDSGLAGQITARAEAPGTYYTQRLGLGFDEITAS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421   81 NLLLVDEDLNVLHGHGMANPANRFHSWVYRARPDVNCIIHTHPLHIAALSTLEVPLQVSHMDLCPLYDDCAFLKDWPGVP 160
Cdd:PRK07090  81 NLLLVDEDLNVLDGEGMPNPANRFHSWIYRARPDVNCIIHTHPPHVAALSMLEVPLVVSHMDTCPLYDDCAFLKDWPGVP 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421  161 VGNEEGEIISAALGDKRAILLSHHGLLATGASIEEACVIAVLLERAAKMQLLAMAAGEIKPIPPALAREAHDWISTPKRH 240
Cdd:PRK07090 161 VGNEEGEIISAALGDKRAILLSHHGQLVAGKSIEEACVLALLIERAARLQLLAMAAGPIKPIPPELAREAHDWISTPKRS 240

                        250       260
                 ....*....|....*....|
gi 15595421  241 GAAFNYYARRCLPRNSDCLS 260
Cdd:PRK07090 241 AATFAYYARRALRRHPDCLD 260
AraD COG0235
5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar ...
 29-235 2.55e-64

5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) [Amino acid transport and metabolism, Carbohydrate transport and metabolism]; 5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) is part of the Pathway/BioSystem: Urea cycle


Pssm-ID: 440005 [Multi-domain]  Cd Length: 208  Bit Score: 199.67  E-value: 2.55e-64
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421  29 WTDRQKLALTCRILFEAGHDSGLAGQITSRGPEaGTYYTQQLGLGFDEISAGNLLLVDEDLNVLHGHGMANPANRFHSWV 108
Cdd:COG0235   4 EELREELAAAGRRLARRGLVDGTAGNISVRLDD-DRFLITPSGVDFGELTPEDLVVVDLDGNVVEGDLKPSSETPLHLAI 82

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421 109 YRARPDVNCIIHTHPLHIAALSTLEVPLQVSHMDL-CPLYDDCAFLkDWPGvPVGNEEGEIISAALGDKRAILLSHHGLL 187
Cdd:COG0235  83 YRARPDVGAVVHTHSPYATALSALGEPLPPLEQTEaAAFLGDVPVV-PYAG-PGTEELAEAIAEALGDRPAVLLRNHGVV 160

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*...
gi 15595421 188 ATGASIEEACVIAVLLERAAKMQLLAMAAGEIKPIPPALAREAHDWIS 235
Cdd:COG0235 161 VWGKDLAEAFDRAEVLEEAARIQLLALALGGPLVLSDEEIDKLARKFG 208
Aldolase_II smart01007
Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and ...
 35-211 1.25e-45

Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and adducins which have not been ascribed any enzymatic function.


Pssm-ID: 214970 [Multi-domain]  Cd Length: 185  Bit Score: 151.25  E-value: 1.25e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421     35 LALTCRILFEAGHDSGLAGQITSRGPEAGTYYTQQLGLGFDEISAGNLLLVDEDLNVLHGHGMANP--ANRFHSWVYRAR 112
Cdd:smart01007   1 LAAACRLLARRGLVEGTGGNISARVGEEDLFLITPSGVDFGELTASDLVVVDLDGNVVEGGGGPKPssETPLHLAIYRAR 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421    113 PDVNCIIHTHPLHIAALSTLEVPLQVSH--MDLCPLYDDCAFLKDWPGVPVGNEEGEIISAALGDK----RAILLSHHGL 186
Cdd:smart01007  81 PDVGAVVHTHSPYATALAALGKPLPLLPteQAAAFLGGEIPYAPYAGPGTELAEEGAELAEALAEAlpdrPAVLLRNHGL 160

                          170       180
                   ....*....|....*....|....*
gi 15595421    187 LATGASIEEACVIAVLLERAAKMQL 211
Cdd:smart01007 161 LVWGKTLEEAFDLAEELEEAAEIQL 185
Aldolase_II pfam00596
Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and ...
 33-211 5.35e-42

Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and adducins which have not been ascribed any enzymatic function.


Pssm-ID: 459862 [Multi-domain]  Cd Length: 178  Bit Score: 141.53  E-value: 5.35e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421    33 QKLALTCRILFEAGHDSGLAGQITSRGPEaGTYYTQQLGLGFDEISAGNLLLVDEDLNVLHGHGMANPANRFHSWVYRAR 112
Cdd:pfam00596   1 EELAAAGRLLARRGLVEGTGGNISVRLPG-DGFLITPSGVDFGELTPEDLVVVDLDGNVVEGGLKPSSETPLHLAIYRAR 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421   113 PDVNCIIHTHPLHIAALSTLEVPLQVSHMDLCPLyddcaFLKDWPGVP---VGNEE-GEIISAALG-DKRAILLSHHGLL 187
Cdd:pfam00596  80 PDAGAVVHTHSPYATALSLAKEGLPPITQEAADF-----LGGDIPIIPyytPGTEElGERIAEALGgDRKAVLLRNHGLL 154

                         170       180
                  ....*....|....*....|....
gi 15595421   188 ATGASIEEACVIAVLLERAAKMQL 211
Cdd:pfam00596 155 VWGKTLEEAFYLAEELERAAEIQL 178
Aldolase_II cd00398
Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes ...
 33-226 1.42e-27

Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). Class II enzymes are further divided into two sub-classes A and B. This family includes class II A aldolases and adducins which has not been ascribed any enzymatic function. Members of this class are primarily bacterial and eukaryotic in origin and include L-fuculose-1-phosphate, L-rhamnulose-1-phosphate aldolases and L-ribulose-5-phosphate 4-epimerases. They all share the ability to promote carbon-carbon bond cleavage and stabilize enolate intermediates using divalent cations.


Pssm-ID: 238232 [Multi-domain]  Cd Length: 209  Bit Score: 105.14  E-value: 1.42e-27
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421  33 QKLALTCRILFEAGHDSGLAGQITSRGPEAGTYYTQQLGLGFDEISAGNLLLVDEDLNVLHGhgmANPAN--RFHSWVYR 110
Cdd:cd00398   5 RKIIAACLLLDLYGWVTGTGGNVSARDRDRGYFLITPSGVDYEEMTASDLVVVDAQGKVVEG---KKPSSetPLHLALYR 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421 111 ARPDVNCIIHTHPLHIAALSTL-EVPLQVSH-MDLCPLYDDCAFLkDWPGVPVGNEE-GEIISAALGDKRAILLSHHGLL 187
Cdd:cd00398  82 ARPDIGCIVHTHSTHATAVSQLkEGLIPAGHtACAVYFTGDIPCT-PYMTPETGEDEiGTQRALGFPNSKAVLLRNHGLF 160

                       170       180       190       200
                ....*....|....*....|....*....|....*....|
gi 15595421 188 ATGASIEEACVIAVLLERAAKMQLLAMA-AGEIKPIPPAL 226
Cdd:cd00398 161 AWGPTLDEAFHLAVVLEVAAEIQLKALSmGGQLPPISLEL 200
 
Name Accession Description Interval E-value
PRK07090 PRK07090
class II aldolase/adducin domain protein; Provisional
 1-260 0e+00

class II aldolase/adducin domain protein; Provisional


Pssm-ID: 180832  Cd Length: 260  Bit Score: 549.62  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421    1 MATTLELPKDQLIQHALKQMKSSLGDNTWTDRQKLALTCRILFEAGHDSGLAGQITSRGPEAGTYYTQQLGLGFDEISAG 80
Cdd:PRK07090   1 MAKTLSLSKDELVARAQRQMDNELKDSGWTLRQKLALTCRILFDAGHDSGLAGQITARAEAPGTYYTQRLGLGFDEITAS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421   81 NLLLVDEDLNVLHGHGMANPANRFHSWVYRARPDVNCIIHTHPLHIAALSTLEVPLQVSHMDLCPLYDDCAFLKDWPGVP 160
Cdd:PRK07090  81 NLLLVDEDLNVLDGEGMPNPANRFHSWIYRARPDVNCIIHTHPPHVAALSMLEVPLVVSHMDTCPLYDDCAFLKDWPGVP 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421  161 VGNEEGEIISAALGDKRAILLSHHGLLATGASIEEACVIAVLLERAAKMQLLAMAAGEIKPIPPALAREAHDWISTPKRH 240
Cdd:PRK07090 161 VGNEEGEIISAALGDKRAILLSHHGQLVAGKSIEEACVLALLIERAARLQLLAMAAGPIKPIPPELAREAHDWISTPKRS 240

                        250       260
                 ....*....|....*....|
gi 15595421  241 GAAFNYYARRCLPRNSDCLS 260
Cdd:PRK07090 241 AATFAYYARRALRRHPDCLD 260
AraD COG0235
5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar ...
 29-235 2.55e-64

5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) [Amino acid transport and metabolism, Carbohydrate transport and metabolism]; 5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) is part of the Pathway/BioSystem: Urea cycle


Pssm-ID: 440005 [Multi-domain]  Cd Length: 208  Bit Score: 199.67  E-value: 2.55e-64
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421  29 WTDRQKLALTCRILFEAGHDSGLAGQITSRGPEaGTYYTQQLGLGFDEISAGNLLLVDEDLNVLHGHGMANPANRFHSWV 108
Cdd:COG0235   4 EELREELAAAGRRLARRGLVDGTAGNISVRLDD-DRFLITPSGVDFGELTPEDLVVVDLDGNVVEGDLKPSSETPLHLAI 82

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421 109 YRARPDVNCIIHTHPLHIAALSTLEVPLQVSHMDL-CPLYDDCAFLkDWPGvPVGNEEGEIISAALGDKRAILLSHHGLL 187
Cdd:COG0235  83 YRARPDVGAVVHTHSPYATALSALGEPLPPLEQTEaAAFLGDVPVV-PYAG-PGTEELAEAIAEALGDRPAVLLRNHGVV 160

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*...
gi 15595421 188 ATGASIEEACVIAVLLERAAKMQLLAMAAGEIKPIPPALAREAHDWIS 235
Cdd:COG0235 161 VWGKDLAEAFDRAEVLEEAARIQLLALALGGPLVLSDEEIDKLARKFG 208
PRK06208 PRK06208
class II aldolase/adducin family protein;
32-246 1.42e-53

class II aldolase/adducin family protein;


Pssm-ID: 235743  Cd Length: 274  Bit Score: 174.41  E-value: 1.42e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421   32 RQKLALTCRILFEAGHDSGLAGQITSRGPE-AGTYYTQQLGLGFDEISAGNLLLVDEDLNVLHGHGMANPAN-RFHSWVY 109
Cdd:PRK06208  44 KQRLAAAFRLFARFGFDEGLAGHITARDPElPDHFWVNPLGVHFSQIKVSDLLLVDHDGEVVEGDRPLNRAAfAIHSAIH 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421  110 RARPDVNCIIHTHPLHIAALSTLEVPLQVSHMDLCPLYDDCAFLKDWPGVPVGNEEGEIISAALGDKRAILLSHHGLLAT 189
Cdd:PRK06208 124 EARPDVVAAAHTHSTYGKAWSTLGRPLDPITQDACAFYEDHALFDDFTGVVVDTSEGRRIAAALGTHKAVILQNHGLLTV 203

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 15595421  190 GASIEEACVIAVLLERAAKMQLLAMAAGEIKPIPPALAREAHDWISTPkrHGAAFNY 246
Cdd:PRK06208 204 GPSVDAAAWWFIALERACQTQLLAEAAGPPQPIDHETARHTRSQVGSE--YGGWFNF 258
Aldolase_II smart01007
Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and ...
 35-211 1.25e-45

Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and adducins which have not been ascribed any enzymatic function.


Pssm-ID: 214970 [Multi-domain]  Cd Length: 185  Bit Score: 151.25  E-value: 1.25e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421     35 LALTCRILFEAGHDSGLAGQITSRGPEAGTYYTQQLGLGFDEISAGNLLLVDEDLNVLHGHGMANP--ANRFHSWVYRAR 112
Cdd:smart01007   1 LAAACRLLARRGLVEGTGGNISARVGEEDLFLITPSGVDFGELTASDLVVVDLDGNVVEGGGGPKPssETPLHLAIYRAR 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421    113 PDVNCIIHTHPLHIAALSTLEVPLQVSH--MDLCPLYDDCAFLKDWPGVPVGNEEGEIISAALGDK----RAILLSHHGL 186
Cdd:smart01007  81 PDVGAVVHTHSPYATALAALGKPLPLLPteQAAAFLGGEIPYAPYAGPGTELAEEGAELAEALAEAlpdrPAVLLRNHGL 160

                          170       180
                   ....*....|....*....|....*
gi 15595421    187 LATGASIEEACVIAVLLERAAKMQL 211
Cdd:smart01007 161 LVWGKTLEEAFDLAEELEEAAEIQL 185
Aldolase_II pfam00596
Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and ...
 33-211 5.35e-42

Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and adducins which have not been ascribed any enzymatic function.


Pssm-ID: 459862 [Multi-domain]  Cd Length: 178  Bit Score: 141.53  E-value: 5.35e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421    33 QKLALTCRILFEAGHDSGLAGQITSRGPEaGTYYTQQLGLGFDEISAGNLLLVDEDLNVLHGHGMANPANRFHSWVYRAR 112
Cdd:pfam00596   1 EELAAAGRLLARRGLVEGTGGNISVRLPG-DGFLITPSGVDFGELTPEDLVVVDLDGNVVEGGLKPSSETPLHLAIYRAR 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421   113 PDVNCIIHTHPLHIAALSTLEVPLQVSHMDLCPLyddcaFLKDWPGVP---VGNEE-GEIISAALG-DKRAILLSHHGLL 187
Cdd:pfam00596  80 PDAGAVVHTHSPYATALSLAKEGLPPITQEAADF-----LGGDIPIIPyytPGTEElGERIAEALGgDRKAVLLRNHGLL 154

                         170       180
                  ....*....|....*....|....
gi 15595421   188 ATGASIEEACVIAVLLERAAKMQL 211
Cdd:pfam00596 155 VWGKTLEEAFYLAEELERAAEIQL 178
PRK06486 PRK06486
aldolase;
15-254 2.13e-28

aldolase;


Pssm-ID: 235814  Cd Length: 262  Bit Score: 108.65  E-value: 2.13e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421   15 HALKQMKSSLGDN--------TWTDRQKLALTCRILFEAGHDSGLAGQITSRGPE-AGTYYTQQLGLGFDEISAGNLLLV 85
Cdd:PRK06486   3 HSLTTDSAPPAGNrplldsdaVAQARVDLAACFRAAARHGLEEGICNHFSAVLPGhDDLFLVNPYGYAFSEITASDLLIC 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421   86 DEDLNVLHGHGMANPANRF-HSWVYRARPDVNCIIHTHPLHIAALSTLE-VPLQVSHMDLCPLYDDCAFLKDWPGVPVGN 163
Cdd:PRK06486  83 DFDGNVLAGRGEPEATAFFiHARIHRAIPRAKAAFHTHMPYATALSLTEgRPLTTLGQTALKFYGRTAVDEDYNGLALDA 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421  164 EEGEIISAALGDKRAILLSHHGLLATGASIEEACVIAVLLERAAKMQLLAMAAG-EIKPIPPALAREAHDWISTPKRHGA 242
Cdd:PRK06486 163 AEGDRIARAMGDADIVFLKNHGVMVCGPRIAEAWDDLYYLERACEVQVLAMSTGrPLVPVDPAIAAAVARQMREGDRESA 242

                        250
                 ....*....|...
gi 15595421  243 AFNYYA-RRCLPR 254
Cdd:PRK06486 243 RLHLEAlRRTLDR 255
PRK07044 PRK07044
aldolase II superfamily protein; Provisional
 71-243 2.63e-28

aldolase II superfamily protein; Provisional


Pssm-ID: 235916  Cd Length: 252  Bit Score: 108.01  E-value: 2.63e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421   71 GLGFDEISAGNLLLVDEDLNVLHGHGMA-NPAN-RFHSWVYRARPDVNCIIHTHPLHIAALSTLEVPLQVSHMDLCPLYD 148
Cdd:PRK07044  58 GLLFDEITASNLVKIDLDGNVVDDSPYPvNPAGfTIHSAIHAARPDAHCVMHTHTTAGVAVSAQRDGLLPLSQHALQFYG 137

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421  149 DCAFlKDWPGVPVGNEEGEIISAALGDKRAILLSHHGLLATGASIEEACVIAVLLERAAKMQLLAMAAG-EIKPIPPALA 227
Cdd:PRK07044 138 RLAY-HDYEGIALDLDEGERLVADLGDKPAMLLRNHGLLTVGRTVAEAFLLMYTLERACEIQVAAQAGGgELVLPPPEVA 216

                        170
                 ....*....|....*.
gi 15595421  228 REAHDWISTPKRHGAA 243
Cdd:PRK07044 217 ERTARQSLFDPGAGAG 232
Aldolase_II cd00398
Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes ...
 33-226 1.42e-27

Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). Class II enzymes are further divided into two sub-classes A and B. This family includes class II A aldolases and adducins which has not been ascribed any enzymatic function. Members of this class are primarily bacterial and eukaryotic in origin and include L-fuculose-1-phosphate, L-rhamnulose-1-phosphate aldolases and L-ribulose-5-phosphate 4-epimerases. They all share the ability to promote carbon-carbon bond cleavage and stabilize enolate intermediates using divalent cations.


Pssm-ID: 238232 [Multi-domain]  Cd Length: 209  Bit Score: 105.14  E-value: 1.42e-27
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421  33 QKLALTCRILFEAGHDSGLAGQITSRGPEAGTYYTQQLGLGFDEISAGNLLLVDEDLNVLHGhgmANPAN--RFHSWVYR 110
Cdd:cd00398   5 RKIIAACLLLDLYGWVTGTGGNVSARDRDRGYFLITPSGVDYEEMTASDLVVVDAQGKVVEG---KKPSSetPLHLALYR 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421 111 ARPDVNCIIHTHPLHIAALSTL-EVPLQVSH-MDLCPLYDDCAFLkDWPGVPVGNEE-GEIISAALGDKRAILLSHHGLL 187
Cdd:cd00398  82 ARPDIGCIVHTHSTHATAVSQLkEGLIPAGHtACAVYFTGDIPCT-PYMTPETGEDEiGTQRALGFPNSKAVLLRNHGLF 160

                       170       180       190       200
                ....*....|....*....|....*....|....*....|
gi 15595421 188 ATGASIEEACVIAVLLERAAKMQLLAMA-AGEIKPIPPAL 226
Cdd:cd00398 161 AWGPTLDEAFHLAVVLEVAAEIQLKALSmGGQLPPISLEL 200
PRK06557 PRK06557
L-ribulose-5-phosphate 4-epimerase; Validated
 52-232 6.39e-20

L-ribulose-5-phosphate 4-epimerase; Validated


Pssm-ID: 235829 [Multi-domain]  Cd Length: 221  Bit Score: 85.06  E-value: 6.39e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421   52 AGQITSRGPEAGTYYTQQLGLGFDEISAGNLLLVDEDLNVLHGHGMANPANRFHSWVYRARPDVNCIIHTHPLHIAALST 131
Cdd:PRK06557  32 SGNVSARDPGTDLVVIKPSGVSYDDLTPEDMVVVDLDGNVVEGDLKPSSDTASHLYVYRHMPDVGGVVHTHSTYATAWAA 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421  132 LEVPLQVshmdLCPLYDDcAFLKDWPGVP---VGNEE-GEIISAAL--GDKRAILLSHHGLLATGASIEEACVIAVLLER 205
Cdd:PRK06557 112 RGEPIPC----VLTAMAD-EFGGPIPVGPfalIGDEAiGKGIVETLkgGRSPAVLMQNHGVFTIGKDAEDAVKAAVMVEE 186

                        170       180
                 ....*....|....*....|....*..
gi 15595421  206 AAKMQLLAMAAGEIKPIPPALAREAHD 232
Cdd:PRK06557 187 VARTVHIARQLGEPIPIPQEEIDRLYD 213
PRK06661 PRK06661
hypothetical protein; Provisional
 32-225 2.18e-19

hypothetical protein; Provisional


Pssm-ID: 168637  Cd Length: 231  Bit Score: 84.11  E-value: 2.18e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421   32 RQKLALTCRILFEAGHDSGLAGQITSRGPEAGTYYTQQLGLGFDEISAGNLLLVDEDLNVLHGHGMA-NPANRF-HSWVY 109
Cdd:PRK06661   4 KYNLAAAYRIMAYLSLDDHTYTHLSARPKNADFYYIYPFGLRFEEVTTENLLKVSLDGQILEGEEYQyNKTGYFiHGSIY 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421  110 RARPDVNCIIHTHPLHIAALSTLEVPL-QVSHMDLcPLYDDCAFLKDWPGVPVGNEEGEIISAALGDKRAILLSHHGLLA 188
Cdd:PRK06661  84 KTRPDISAIFHYHTPASIAVSALKCGLlPISQWAL-HFYDRISYHNYNSLALDADKQSSRLVNDLKQNYVMLLRNHGAIT 162

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 15595421  189 TGASIEEACVIAVLLERAAKMQLLAMAAGEIKPIPPA 225
Cdd:PRK06661 163 CGKTIHEAMFYTYHLEQACKTQCLLNSTKKQELIIPS 199
PRK07490 PRK07490
hypothetical protein; Provisional
 26-233 6.17e-18

hypothetical protein; Provisional


Pssm-ID: 236031 [Multi-domain]  Cd Length: 245  Bit Score: 80.15  E-value: 6.17e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421   26 DNTWTDRQKLALTCRILFEAGHDSGLAGQITSRGPEAGT-YYTQQLGLGFDEISAGNLLLVD-EDLNVLHGHGMANP-AN 102
Cdd:PRK07490   6 SDEEQIRVDLAAAFRWIARLGMHEAVANHFSAAVSADGKqFLLNPKWKHFSRIRASDLLLLDaDDPSTAERPDVPDAtAW 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421  103 RFHSWVYRARPDVNCIIHTHPLHIAALSTLEVPlqvshmDLCPLYDDCAFLKDWPGVPVG------NEEGEIISAALGDK 176
Cdd:PRK07490  86 AIHGQIHRRLPHARCVMHVHSVYATALACLADP------TLPPIDQNTARFFNRVAVDTLyggmalEEEGERLAGLLGDK 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 15595421  177 RAILLSHHGLLATGASIEEACVIAVLLERAAKMQLLAMAAG-EIKPIPPALARE-AHDW 233
Cdd:PRK07490 160 RRLLMGNHGVLVTGDTVAEAFDDLYYFERACQTYITALSTGqPLRVLSDAVAEKtARDW 218
PRK08087 PRK08087
L-fuculose-phosphate aldolase;
31-223 2.97e-16

L-fuculose-phosphate aldolase;


Pssm-ID: 181226 [Multi-domain]  Cd Length: 215  Bit Score: 75.16  E-value: 2.97e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421   31 DRQKLAL----TCRILFEAGHDSGLAGQITSRgpeagtYYTQQL----GLGFDEISAGNLLLVDEDLNVLHGHgMANPAN 102
Cdd:PRK08087   2 ERNKLARqiidTCLEMTRLGLNQGTAGNVSVR------YQDGMLitptGIPYEKLTESHIVFVDGNGKHEEGK-LPSSEW 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421  103 RFHSWVYRARPDVNCIIHTHPLHIAALSTLEVPLQVSHMDLCplyddCAFLKDWPGVPVGN----EEGEIISAALGDKRA 178
Cdd:PRK08087  75 RFHMAAYQTRPDANAVVHNHAVHCTAVSILNRPIPAIHYMIA-----AAGGNSIPCAPYATfgtrELSEHVALALKNRKA 149

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 15595421  179 ILLSHHGLLATGASIEEACVIAVLLERAAKMQLLAMAAGEikPIP 223
Cdd:PRK08087 150 TLLQHHGLIACEVNLEKALWLAHEVEVLAQLYLKTLAITD--PVP 192
PRK08130 PRK08130
putative aldolase; Validated
 39-212 4.46e-15

putative aldolase; Validated


Pssm-ID: 181241 [Multi-domain]  Cd Length: 213  Bit Score: 71.83  E-value: 4.46e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421   39 CRI---LFEAGHDSGLAGQITSRGPEAGTYYTQQlGLGFDEISAGNLLLVDEDLNVLHGhgmaNPANR---FHSWVYRAR 112
Cdd:PRK08130  11 VRLgrsLFQRGYTVGSAGNISARLDDGGWLVTPT-GSCLGRLDPARLSKVDADGNWLSG----DKPSKevpLHRAIYRNN 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421  113 PDVNCIIHTHPLHIAALSTLEV--------PL------QVSHMDLCPLYDdcaflkdwPGVPvgnEEGEIISAALGDKRA 178
Cdd:PRK08130  86 PECGAVVHLHSTHLTALSCLGGldptnvlpPFtpyyvmRVGHVPLIPYYR--------PGDP---AIAEALAGLAARYRA 154

                        170       180       190
                 ....*....|....*....|....*....|....
gi 15595421  179 ILLSHHGLLATGASIEEACVIAVLLERAAKMQLL 212
Cdd:PRK08130 155 VLLANHGPVVWGSSLEAAVNATEELEETAKLILL 188
PRK06833 PRK06833
L-fuculose-phosphate aldolase;
31-223 2.02e-13

L-fuculose-phosphate aldolase;


Pssm-ID: 180717 [Multi-domain]  Cd Length: 214  Bit Score: 67.47  E-value: 2.02e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421   31 DRQKLALTCRILFEAGHDSGLAGQITSRGPEAGTYYTQQLGLGFDEISAGNLLLVDEDLNVLHGHGMANPANRFHSWVYR 110
Cdd:PRK06833   6 EREEIVAYGKKLISSGLTKGTGGNISIFNREQGLMAITPSGIDYFEIKPEDIVIMDLDGKVVEGERKPSSELDMHLIFYR 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421  111 ARPDVNCIIHTHPLHIAALSTLEVPLQVSHMDLcplyddcAFLKdwPGVPVGN-------EEGEIISAALGDKRAILLSH 183
Cdd:PRK06833  86 NREDINAIVHTHSPYATTLACLGWELPAVHYLI-------AVAG--PNVRCAEyatfgtkELAENAFEAMEDRRAVLLAN 156

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 15595421  184 HGLLATGASIEEACVIAVLLERAAKMQLLAMAAGEIKPIP 223
Cdd:PRK06833 157 HGLLAGANNLKNAFNIAEEIEFCAEIYYQTKSIGEPKLLP 196
PRK08333 PRK08333
aldolase;
32-209 1.53e-12

aldolase;


Pssm-ID: 181393 [Multi-domain]  Cd Length: 184  Bit Score: 64.46  E-value: 1.53e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421   32 RQKLALTCRILFEAGHDSGLAGQITSRgpeAGTY-YTQQLGLGFDEISAGNLLLVDEDLNVLHGhgmANPAN--RFHSWV 108
Cdd:PRK08333   5 KAQLVKYSKLAHERGLTAAFGGNLSIR---VGNLvFIKATGSVMDELTREQVAVIDLNGNQLSS---VRPSSeyRLHLAV 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421  109 YRARPDVNCIIHTHPLHIAALSTL---EVPLQVSHMDLcplyddcaFLKDWPGV---PVGNEE-GEIISAALGDKRAILL 181
Cdd:PRK08333  79 YRNRPDVRAIAHLHPPYSIVASTLleeELPIITPEAEL--------YLKKIPILpfrPAGSVElAEQVAEAMKEYDAVIM 150

                        170       180
                 ....*....|....*....|....*...
gi 15595421  182 SHHGLLATGASIEEACVIAVLLERAAKM 209
Cdd:PRK08333 151 ERHGIVTVGRSLREAFYKAELVEESAKL 178
PRK05874 PRK05874
L-fuculose-phosphate aldolase; Validated
 50-228 3.88e-12

L-fuculose-phosphate aldolase; Validated


Pssm-ID: 102036 [Multi-domain]  Cd Length: 217  Bit Score: 63.89  E-value: 3.88e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421   50 GLAGQITSRGPEAGTYYTQQlGLGFDEISAGNLLLVDEDLNVLHGHGMANPAN--RFHSWVYRARPDVNCIIHTHPL--H 125
Cdd:PRK05874  26 GTAGNISARRSDGNVVITPS-SVDYAEMLLHDLVLVDAGGAVLHAKDGRSPSTelNLHLACYRAFDDIGSVIHSHPVwaT 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421  126 IAALSTLEVPLQVSHMDL-CPLYDDCAFLKDwPGVPvgnEEGEIISAALGDKRAILLSHHGLLATGASIEEACVIAVLLE 204
Cdd:PRK05874 105 MFAVAHEPIPACIDEFAIyCGGDVRCTEYAA-SGTP---EVGRNAVRALEGRAAALIANHGLVAVGPRPDQVLRVTALVE 180

                        170       180
                 ....*....|....*....|....
gi 15595421  205 RAAKMQLLAMAAGEIKPIPPALAR 228
Cdd:PRK05874 181 RTAQIVWGARALGGPVPIPEDVCR 204
PRK08660 PRK08660
aldolase;
33-213 7.06e-11

aldolase;


Pssm-ID: 181527 [Multi-domain]  Cd Length: 181  Bit Score: 59.59  E-value: 7.06e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421   33 QKLALTCRILFEAGHDSGLAGQITSRGpEAGTYYTQQlGLGFDEISAGNLLLVDedlnvLHGHG----MANPANRFHSWV 108
Cdd:PRK08660   3 QEFARIGKKLFAHGLVSSHFGNISVRT-GDGLLITRT-GSMLDEITEGDVIEVG-----IDDDGsvdpLASSETPVHRAI 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421  109 YRaRPDVNCIIHTHPLHIAALSTLE---VPLqvshmDLCPLYddcaFLKDWPGV--PVGNEE-GEIISAALGDKRAILLS 182
Cdd:PRK08660  76 YR-RTSAKAIVHAHPPYAVALSLLEdeiVPL-----DSEGLY----FLGTIPVVggDIGSGElAENVARALSEHKGVVVR 145

                        170       180       190
                 ....*....|....*....|....*....|.
gi 15595421  183 HHGLLATGASIEEACVIAVLLERAAKMQLLA 213
Cdd:PRK08660 146 GHGTFAIGKTLEEAYIYTSQLEHSCKVLYLV 176
sgaE PRK12348
L-ribulose-5-phosphate 4-epimerase; Reviewed
 71-250 1.80e-08

L-ribulose-5-phosphate 4-epimerase; Reviewed


Pssm-ID: 183460  Cd Length: 228  Bit Score: 53.65  E-value: 1.80e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421   71 GLGFDEISAGNLLLVDEDLNVLHGHGMANPANRFHSWVYRARPDVNCIIHTHPLHIAAL--STLEVP-LQVSHMDLcpLY 147
Cdd:PRK12348  44 GVAYETMKADDMVVVDMSGKVVEGEYRPSSDTATHLELYRRYPSLGGIVHTHSTHATAWaqAGLAIPaLGTTHADY--FF 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421  148 DDCAFLKDWPGVPVGNE----EGEIISAALGDKR-----AILLSHHGLLATGASIEEACVIAVLLERAAKMQLLAMAAG- 217
Cdd:PRK12348 122 GDIPCTRGLSEEEVQGEyelnTGKVIIETLGNAEplhtpGIVVYQHGPFAWGKDAHDAVHNAVVMEEVAKMAWIARGINp 201

                        170       180       190
                 ....*....|....*....|....*....|...
gi 15595421  218 EIKPIPPALaREAHDWistpKRHGAAfNYYARR 250
Cdd:PRK12348 202 QLNHIDSYL-MNKHFM----RKHGPN-AYYGQK 228
PRK06357 PRK06357
hypothetical protein; Provisional
 31-220 4.11e-08

hypothetical protein; Provisional


Pssm-ID: 180541 [Multi-domain]  Cd Length: 216  Bit Score: 52.47  E-value: 4.11e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421   31 DRQKLALTCRILFEAGHDSGLAGQITSR-GPEAGTYY---------TQQLGlgfdEISAGNLLLVD-EDLNVLHGHGMAN 99
Cdd:PRK06357   6 EREDLAKVVKTMFDRKETNAAGGNISVRmTAEKNKEYiimtptlmsEAKLC----DLSPYQILVVDlNTGEVIEGVGRVT 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421  100 PANRFHSWVYRARPDVNCIIHTHPLH--IAALSTLEVPlqvshmDLCPLYDDCAFLKDWPGVPVGNEE-GEIISAAL--- 173
Cdd:PRK06357  82 REINMHEAAYVANPKIKCVYHSHAKEsmFWATLGLEMP------NLTEATQKLGKIPTLPFAPATSPElAEIVRKHLiel 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 15595421  174 GDKR---AILLSHHGLLATGASIEEACVIAVLLERAAKM---QLLAMAAGEIK 220
Cdd:PRK06357 156 GDKAvpsAFLLNSHGIVITDTSLHKAYDILETIEWNAYIayqATVFDKLGLLK 208
araD PRK13145
L-ribulose-5-phosphate 4-epimerase; Provisional
 61-226 1.42e-07

L-ribulose-5-phosphate 4-epimerase; Provisional


Pssm-ID: 183870 [Multi-domain]  Cd Length: 234  Bit Score: 50.99  E-value: 1.42e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421   61 EAGTYYTQQLGLGFDEISAGNLLLVDEDLNVLHGHgmANPANRF--HSWVYRARPDVNCIIHTHPLHIA--ALSTLEVPL 136
Cdd:PRK13145  36 ELGRIVIKPSGVDYDELTPENMVVTDLDGNVVEGD--LNPSSDLptHVELYKAWPEVGGIVHTHSTEAVgwAQAGRDIPF 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421  137 Q-VSHMDLcpLYDD--CA--FLKDWPGVPVGNEEGEIISAALGDKR-------AILLSHHGLLATGASIEEACVIAVLLE 204
Cdd:PRK13145 114 YgTTHADY--FYGPipCArsLTKDEVNGAYEKETGSVIIEEFEKRGldpmavpGIVVRNHGPFTWGKNPEQAVYHSVVLE 191

                        170       180
                 ....*....|....*....|...
gi 15595421  205 RAAKM-QLLAMAAGEIKPIPPAL 226
Cdd:PRK13145 192 EVAKMnRLTEQINPRVEPAPQYI 214
PRK03634 PRK03634
rhamnulose-1-phosphate aldolase; Provisional
 113-220 7.33e-07

rhamnulose-1-phosphate aldolase; Provisional


Pssm-ID: 179615 [Multi-domain]  Cd Length: 274  Bit Score: 49.21  E-value: 7.33e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421  113 PDVNCIIHTHPLHIAALS-TLEVPLQVSHMDLCPLYDDC-AFLKDWPG-----VPVGNEEGEIISAALGDKRAILLSHHG 185
Cdd:PRK03634 134 GKDRVIMHCHATNLIALTyVLELDEAVFTRTLWEMSTEClVVFPDGVGivpwmVPGTDEIGQATAEKMQKHDLVLWPKHG 213

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 15595421  186 LLATGASIEEACVIAVLLERAAKMQLLAMAAGEIK 220
Cdd:PRK03634 214 VFGSGPTLDEAFGLIDTAEKSAEIYVKVLSMGGMK 248
araD PRK13213
L-ribulose-5-phosphate 4-epimerase; Reviewed
 53-212 4.98e-04

L-ribulose-5-phosphate 4-epimerase; Reviewed


Pssm-ID: 106181  Cd Length: 231  Bit Score: 40.48  E-value: 4.98e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421   53 GQITSRGPEAGTYYTQQLGLGFDEISAGNLLLVD-EDLNVLHGHGMANPANRFHSWVYRARPDVNCIIHTHPLH------ 125
Cdd:PRK13213  27 GNVSGIDREHGLVVIKPSGVEYDVMSVNDMVVVDlATGKVVEGDKKPSSDTDTHLVLYRAFAEIGGIVHTHSRHatiwaq 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595421  126 ----IAALSTLEVPLQVSHMDLCPLYDDCAFLKDWPgvpvgNEEGEIISAAL-------GDKRAILLSHHGLLATGASIE 194
Cdd:PRK13213 107 agksLSALGTTHADYFYGPIPCTRLMTEAEITGDYE-----HETGKVIVETFaeqglraADIPAVLVNGHGPFAWGSNAA 181

                        170
                 ....*....|....*...
gi 15595421  195 EACVIAVLLERAAKMQLL 212
Cdd:PRK13213 182 NAVHNAVVLEEIAYMNLF 199
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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