|
Name |
Accession |
Description |
Interval |
E-value |
| dgt |
PRK04926 |
deoxyguanosinetriphosphate triphosphohydrolase; Provisional |
2-498 |
0e+00 |
|
deoxyguanosinetriphosphate triphosphohydrolase; Provisional
Pssm-ID: 235320 [Multi-domain] Cd Length: 503 Bit Score: 781.80 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 2 PGAVDFKERISRQRPHDREtyghAGNTDLQDIVYQLESDRGRIVNSAAVRRLQQKTQVFPLERNAAVRSRLTHSLEVQQT 81
Cdd:PRK04926 1 MAMIDFRKKINWQRRYRSP----QGVKTEHEILRIFESDRGRIINSAAIRRLQQKTQVFPLERNAAVRSRLTHSLEVQQV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 82 GRFIVRTLFRQLGPRA--AEVGLDGLEGALESLVEMACLMHDVGNPPFGHFGEYAINDWFERNLDALF------------ 147
Cdd:PRK04926 77 GRYIAKEILSRLKEQKllEAYGLDELTGPFESIVEMACLMHDIGNPPFGHFGEAAINDWFRQRLDPDAesqpltddrcsv 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 148 -ERRIPPGQ-GDGLLQQRMLTDLKHFEGNAQAIRLVVKLLRLNLTYTQTAGLLKYVRPAYEPKPDkAAANHYLNKKPGFY 225
Cdd:PRK04926 157 aALRLRDGEePLNELRRKIRQDLCHFEGNAQGIRLVHTLLRLNLTYAQVACILKYTRPAWWRGPT-PASHHYLMKKPGYY 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 226 LSEEAFVDELRRVLGMRPGTRHPVAYIMEAADDISYCLADIEDSVEKGILDIRQLADLLVKKFAVHHSPDapipgdadnm 305
Cdd:PRK04926 236 LSEEAYVARLRKELNLAPYSRFPLTYIMEAADDISYCIADLEDAVEKRIFSVEQLYHHLHEAWGEHEKGD---------- 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 306 SFQRMVDYSLEKAEREPINKVSE--FFIRLRVKMIHPLVQHAAQQFIDNFEAVHAGTLGRALMEDGSLPHAIVQTFKDVA 383
Cdd:PRK04926 306 LFSLVVENAWEKSRANSLSRSSEdqFFMYLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNQALLEDASPASRLLKTFKNVA 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 384 MEWVFCHPEVETLELQGYRIIQGLLDFYAPLLRLPAEEFQALAEGRQ-AAAPHPQLLVRRLPSQQIKAYLEAMKGVAEDP 462
Cdd:PRK04926 386 RKHVFSHPEVEQLELQGYRVISGLLDIYSPLLALPLEDFTELVEKERhKRYPIETRLFHKLSTRHRLAYVEAVSKLPSDS 465
|
490 500 510
....*....|....*....|....*....|....*..
gi 15596321 463 L-QRQWEFYHRCRMLQDFVSGMTDQHAQDEYRALSAL 498
Cdd:PRK04926 466 PeFPLWEYYYRARLIQDYISGMTDLYAWDEYRRLMAV 502
|
|
| Dgt |
COG0232 |
dGTP triphosphohydrolase [Nucleotide transport and metabolism]; |
38-496 |
3.16e-110 |
|
dGTP triphosphohydrolase [Nucleotide transport and metabolism];
Pssm-ID: 440002 [Multi-domain] Cd Length: 345 Bit Score: 330.58 E-value: 3.16e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 38 ESDRGRIVNSAAVRRLQQKTQVFPLERNAAVRSRLTHSLEVQQTGRFIVRTLfrqlgpraaevgldgleGALESLVEMAC 117
Cdd:COG0232 8 QRDRDRIIHSAAFRRLQDKTQVFPLPEGDHYRTRLTHSLEVAQIARSIARAL-----------------GLNEDLVEAAA 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 118 LMHDVGNPPFGHFGEYAINDWFErnldalferrippgqgdgllqqrmltDLKHFEGNAQAIRLVVKLLR------LNLTY 191
Cdd:COG0232 71 LAHDLGHPPFGHAGEDALNELFR--------------------------DLGGFEGNAQSLRILTRLEKryafggLNLTY 124
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 192 TQTAGLLKYVRPAYEPKPDkaaanhylnKKPGFYLSEEAFVDELRRVLGMRPGT--RHPVAYIMEAADDISYCLADIEDS 269
Cdd:COG0232 125 ATLDGILKYPGPSLAAPKP---------KPKGFYQSEKDVFDWVREELGLLALGrpRTLEAQIVELADDIAYSVHDLEDA 195
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 270 VEKGILDIRQLADLLVKkfavhhspdapipgdadnmsfqrmvDYSLEKaerepinkvSEFFIRLRVKMIHPLVQHAAQQF 349
Cdd:COG0232 196 IRAGLLSLEDLPELLEY-------------------------LGPLDE---------RRRLGELRSRLIGRLVTDVIEAS 241
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 350 IDNFeavhagtLGRALMEDGSLPHAIVQTFKDVAMEWVFCHPEVETLELQGYRIIQGLLDFYApllrlpaeefqalaegr 429
Cdd:COG0232 242 RENL-------FDGPLIAFSPEVAAALKELKKFLFERVYRHPEVLRLELKGRRIIRELFDAFL----------------- 297
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15596321 430 qaaaphpQLLVRRLPSQQIKAYleamkgvaedplQRQWEFYHRCRMLQDFVSGMTDQHAQDEYRALS 496
Cdd:COG0232 298 -------EDPLELLPEEFRERY------------EAADDEYGRLRVVADYIAGMTDRYALRLYRRLF 345
|
|
| dGTP_triPase |
TIGR01353 |
deoxyguanosinetriphosphate triphosphohydrolase, putative; dGTP triphosphohydrolase (dgt) ... |
36-495 |
1.15e-106 |
|
deoxyguanosinetriphosphate triphosphohydrolase, putative; dGTP triphosphohydrolase (dgt) releases inorganic triphosphate, an unusual activity reaction product, from GTP. Its activity has been called limited to the Enterobacteriaceae, although homologous sequences are detected elsewhere. This finding casts doubt on whether the activity is shared in other species. In several of these other species, the homologous gene is found in an apparent operon with dnaG, the DNA primase gene. The enzyme from E. coli was shown to bind coopertatively to single stranded DNA. The biological role of dgt is unknown. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]
Pssm-ID: 273571 [Multi-domain] Cd Length: 381 Bit Score: 322.78 E-value: 1.15e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 36 QLESDRGRIVNSAAVRRLQQKTQVFPLERNAAVRSRLTHSLEVQQTGRFIVRTLFRQLGPRAAEVGLDglegalESLVEM 115
Cdd:TIGR01353 4 PFERDYDRIIHSSAFRRLQDKTQVFPLAENDFVRTRLTHSLEVAQVGRSIANLIGLRYDLELEELGPF------ERLAET 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 116 ACLMHDVGNPPFGHFGEYAINDWFERNldalferrippgqgdgllqqrmltdLKHFEGNAQAIRLVVKLLR-------LN 188
Cdd:TIGR01353 78 ACLAHDIGNPPFGHAGERALNDWMREY-------------------------GPGFEGNAQTFRILTTLEKrrrakggLN 132
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 189 LTYTQTAGLLKYVRPAYEpkpdKAAANHYLNKKPGFYLSEEAFVDELRRVLGMRpGTRHPVAYIMEAADDISYCLADIED 268
Cdd:TIGR01353 133 LTWRTLAGILKYPRPSSE----DAFKGGYLNKKKGIYDSELAVFDRVAELLGLT-WYRSPLAQLMEAADDIAYTVHDLED 207
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 269 SVEKGILDIRQLADLLvkkfavhhspdAPIPGDADNMSfqRMVDyslekaerEPINKVSEFFIRLRVKMIHPLVQHAAQ- 347
Cdd:TIGR01353 208 AIKLGLLTFDDLQHLL-----------LIQAGFEELGS--EMTD--------LSISAENEQIRSLRGKLITDLIESVAKa 266
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 348 QFIDNFEAVHAGTLGRALMEDGSLPHAIVQTFKDVAMEWVFCHPEVETLELQGYRIIQGLLDFYAPLLRlpaeefqalae 427
Cdd:TIGR01353 267 EFSSHLVAILIGTFHHTLVEFSPRLAELLEALKKFLRKRVYRHPDVERIEYQGEQIITGLFDAFMPDLP----------- 335
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15596321 428 grqaAAPHPQLLVRRLPSqqikayleamkgvaedplqrQWEFYHRCRMLQDFVSGMTDQHAQDEYRAL 495
Cdd:TIGR01353 336 ----PRLLPPELRSKLRK--------------------AEDNYYKARVVCDYIAGMTDRYALEEYRRL 379
|
|
| HDc |
smart00471 |
Metal dependent phosphohydrolases with conserved 'HD' motif; Includes eukaryotic cyclic ... |
67-140 |
5.83e-04 |
|
Metal dependent phosphohydrolases with conserved 'HD' motif; Includes eukaryotic cyclic nucleotide phosphodiesterases (PDEc). This profile/HMM does not detect HD homologues in bacterial glycine aminoacyl-tRNA synthetases (beta subunit).
Pssm-ID: 214679 [Multi-domain] Cd Length: 124 Bit Score: 39.97 E-value: 5.83e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15596321 67 AVRSRLTHSLEVQQTGRFIvrtlfrqlgprAAEVGLDGLEgalesLVEMACLMHDVGNPPFGHFGEYAINDWFE 140
Cdd:smart00471 1 SDYHVFEHSLRVAQLAAAL-----------AEELGLLDIE-----LLLLAALLHDIGKPGTPDSFLVKTSVLED 58
|
|
| HD |
pfam01966 |
HD domain; HD domains are metal dependent phosphohydrolases. |
71-129 |
4.36e-03 |
|
HD domain; HD domains are metal dependent phosphohydrolases.
Pssm-ID: 460398 [Multi-domain] Cd Length: 110 Bit Score: 36.83 E-value: 4.36e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 15596321 71 RLTHSLEVQQtgrfIVRTLFRQLGPRAAEvgldglegalesLVEMACLMHDVGNPPFGH 129
Cdd:pfam01966 1 RLEHSLRVAL----LARELAEELGELDRE------------LLLLAALLHDIGKGPFGD 43
|
|
| HDc |
cd00077 |
Metal dependent phosphohydrolases with conserved 'HD' motif |
69-135 |
6.76e-03 |
|
Metal dependent phosphohydrolases with conserved 'HD' motif
Pssm-ID: 238032 [Multi-domain] Cd Length: 145 Bit Score: 37.32 E-value: 6.76e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15596321 69 RSRLTHSLEVQQTGRFIVRTLfrqlgpraaevgldGLEGALESLVEMACLMHDVGNPPFGHFGEYAI 135
Cdd:cd00077 1 EHRFEHSLRVAQLARRLAEEL--------------GLSEEDIELLRLAALLHDIGKPGTPDAITEEE 53
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| dgt |
PRK04926 |
deoxyguanosinetriphosphate triphosphohydrolase; Provisional |
2-498 |
0e+00 |
|
deoxyguanosinetriphosphate triphosphohydrolase; Provisional
Pssm-ID: 235320 [Multi-domain] Cd Length: 503 Bit Score: 781.80 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 2 PGAVDFKERISRQRPHDREtyghAGNTDLQDIVYQLESDRGRIVNSAAVRRLQQKTQVFPLERNAAVRSRLTHSLEVQQT 81
Cdd:PRK04926 1 MAMIDFRKKINWQRRYRSP----QGVKTEHEILRIFESDRGRIINSAAIRRLQQKTQVFPLERNAAVRSRLTHSLEVQQV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 82 GRFIVRTLFRQLGPRA--AEVGLDGLEGALESLVEMACLMHDVGNPPFGHFGEYAINDWFERNLDALF------------ 147
Cdd:PRK04926 77 GRYIAKEILSRLKEQKllEAYGLDELTGPFESIVEMACLMHDIGNPPFGHFGEAAINDWFRQRLDPDAesqpltddrcsv 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 148 -ERRIPPGQ-GDGLLQQRMLTDLKHFEGNAQAIRLVVKLLRLNLTYTQTAGLLKYVRPAYEPKPDkAAANHYLNKKPGFY 225
Cdd:PRK04926 157 aALRLRDGEePLNELRRKIRQDLCHFEGNAQGIRLVHTLLRLNLTYAQVACILKYTRPAWWRGPT-PASHHYLMKKPGYY 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 226 LSEEAFVDELRRVLGMRPGTRHPVAYIMEAADDISYCLADIEDSVEKGILDIRQLADLLVKKFAVHHSPDapipgdadnm 305
Cdd:PRK04926 236 LSEEAYVARLRKELNLAPYSRFPLTYIMEAADDISYCIADLEDAVEKRIFSVEQLYHHLHEAWGEHEKGD---------- 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 306 SFQRMVDYSLEKAEREPINKVSE--FFIRLRVKMIHPLVQHAAQQFIDNFEAVHAGTLGRALMEDGSLPHAIVQTFKDVA 383
Cdd:PRK04926 306 LFSLVVENAWEKSRANSLSRSSEdqFFMYLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNQALLEDASPASRLLKTFKNVA 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 384 MEWVFCHPEVETLELQGYRIIQGLLDFYAPLLRLPAEEFQALAEGRQ-AAAPHPQLLVRRLPSQQIKAYLEAMKGVAEDP 462
Cdd:PRK04926 386 RKHVFSHPEVEQLELQGYRVISGLLDIYSPLLALPLEDFTELVEKERhKRYPIETRLFHKLSTRHRLAYVEAVSKLPSDS 465
|
490 500 510
....*....|....*....|....*....|....*..
gi 15596321 463 L-QRQWEFYHRCRMLQDFVSGMTDQHAQDEYRALSAL 498
Cdd:PRK04926 466 PeFPLWEYYYRARLIQDYISGMTDLYAWDEYRRLMAV 502
|
|
| Dgt |
COG0232 |
dGTP triphosphohydrolase [Nucleotide transport and metabolism]; |
38-496 |
3.16e-110 |
|
dGTP triphosphohydrolase [Nucleotide transport and metabolism];
Pssm-ID: 440002 [Multi-domain] Cd Length: 345 Bit Score: 330.58 E-value: 3.16e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 38 ESDRGRIVNSAAVRRLQQKTQVFPLERNAAVRSRLTHSLEVQQTGRFIVRTLfrqlgpraaevgldgleGALESLVEMAC 117
Cdd:COG0232 8 QRDRDRIIHSAAFRRLQDKTQVFPLPEGDHYRTRLTHSLEVAQIARSIARAL-----------------GLNEDLVEAAA 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 118 LMHDVGNPPFGHFGEYAINDWFErnldalferrippgqgdgllqqrmltDLKHFEGNAQAIRLVVKLLR------LNLTY 191
Cdd:COG0232 71 LAHDLGHPPFGHAGEDALNELFR--------------------------DLGGFEGNAQSLRILTRLEKryafggLNLTY 124
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 192 TQTAGLLKYVRPAYEPKPDkaaanhylnKKPGFYLSEEAFVDELRRVLGMRPGT--RHPVAYIMEAADDISYCLADIEDS 269
Cdd:COG0232 125 ATLDGILKYPGPSLAAPKP---------KPKGFYQSEKDVFDWVREELGLLALGrpRTLEAQIVELADDIAYSVHDLEDA 195
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 270 VEKGILDIRQLADLLVKkfavhhspdapipgdadnmsfqrmvDYSLEKaerepinkvSEFFIRLRVKMIHPLVQHAAQQF 349
Cdd:COG0232 196 IRAGLLSLEDLPELLEY-------------------------LGPLDE---------RRRLGELRSRLIGRLVTDVIEAS 241
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 350 IDNFeavhagtLGRALMEDGSLPHAIVQTFKDVAMEWVFCHPEVETLELQGYRIIQGLLDFYApllrlpaeefqalaegr 429
Cdd:COG0232 242 RENL-------FDGPLIAFSPEVAAALKELKKFLFERVYRHPEVLRLELKGRRIIRELFDAFL----------------- 297
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15596321 430 qaaaphpQLLVRRLPSQQIKAYleamkgvaedplQRQWEFYHRCRMLQDFVSGMTDQHAQDEYRALS 496
Cdd:COG0232 298 -------EDPLELLPEEFRERY------------EAADDEYGRLRVVADYIAGMTDRYALRLYRRLF 345
|
|
| dGTP_triPase |
TIGR01353 |
deoxyguanosinetriphosphate triphosphohydrolase, putative; dGTP triphosphohydrolase (dgt) ... |
36-495 |
1.15e-106 |
|
deoxyguanosinetriphosphate triphosphohydrolase, putative; dGTP triphosphohydrolase (dgt) releases inorganic triphosphate, an unusual activity reaction product, from GTP. Its activity has been called limited to the Enterobacteriaceae, although homologous sequences are detected elsewhere. This finding casts doubt on whether the activity is shared in other species. In several of these other species, the homologous gene is found in an apparent operon with dnaG, the DNA primase gene. The enzyme from E. coli was shown to bind coopertatively to single stranded DNA. The biological role of dgt is unknown. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]
Pssm-ID: 273571 [Multi-domain] Cd Length: 381 Bit Score: 322.78 E-value: 1.15e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 36 QLESDRGRIVNSAAVRRLQQKTQVFPLERNAAVRSRLTHSLEVQQTGRFIVRTLFRQLGPRAAEVGLDglegalESLVEM 115
Cdd:TIGR01353 4 PFERDYDRIIHSSAFRRLQDKTQVFPLAENDFVRTRLTHSLEVAQVGRSIANLIGLRYDLELEELGPF------ERLAET 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 116 ACLMHDVGNPPFGHFGEYAINDWFERNldalferrippgqgdgllqqrmltdLKHFEGNAQAIRLVVKLLR-------LN 188
Cdd:TIGR01353 78 ACLAHDIGNPPFGHAGERALNDWMREY-------------------------GPGFEGNAQTFRILTTLEKrrrakggLN 132
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 189 LTYTQTAGLLKYVRPAYEpkpdKAAANHYLNKKPGFYLSEEAFVDELRRVLGMRpGTRHPVAYIMEAADDISYCLADIED 268
Cdd:TIGR01353 133 LTWRTLAGILKYPRPSSE----DAFKGGYLNKKKGIYDSELAVFDRVAELLGLT-WYRSPLAQLMEAADDIAYTVHDLED 207
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 269 SVEKGILDIRQLADLLvkkfavhhspdAPIPGDADNMSfqRMVDyslekaerEPINKVSEFFIRLRVKMIHPLVQHAAQ- 347
Cdd:TIGR01353 208 AIKLGLLTFDDLQHLL-----------LIQAGFEELGS--EMTD--------LSISAENEQIRSLRGKLITDLIESVAKa 266
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 348 QFIDNFEAVHAGTLGRALMEDGSLPHAIVQTFKDVAMEWVFCHPEVETLELQGYRIIQGLLDFYAPLLRlpaeefqalae 427
Cdd:TIGR01353 267 EFSSHLVAILIGTFHHTLVEFSPRLAELLEALKKFLRKRVYRHPDVERIEYQGEQIITGLFDAFMPDLP----------- 335
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15596321 428 grqaAAPHPQLLVRRLPSqqikayleamkgvaedplqrQWEFYHRCRMLQDFVSGMTDQHAQDEYRAL 495
Cdd:TIGR01353 336 ----PRLLPPELRSKLRK--------------------AEDNYYKARVVCDYIAGMTDRYALEEYRRL 379
|
|
| PRK01096 |
PRK01096 |
deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional |
38-496 |
1.32e-94 |
|
deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional
Pssm-ID: 234897 [Multi-domain] Cd Length: 440 Bit Score: 293.75 E-value: 1.32e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 38 ESDRGRIVNSAAVRRLQQKTQVFPLERNAAVRSRLTHSLEVQQTGrfivrtlfRQLGPRAAEVGLDGLE------GALES 111
Cdd:PRK01096 29 HKDYDRIIFSGSFRRLQRKTQVHPLAKNDHIHTRLTHSLEVSCVG--------RSLGMRVGETLKEEKLpdwispADIGA 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 112 LVEMACLMHDVGNPPFGHFGEYAINDWFERNLDALFERRIPPgqgdgllqqRMLTDLKHFEGNAQAIRLVVKLLRL---- 187
Cdd:PRK01096 101 IVQSACLAHDIGNPPFGHFGEDAIREWFQDAAGRGFLDDLSP---------QERADFLNFEGNAQGFRVLTKLEYHqddg 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 188 --NLTYTQTAGLLKYvrPAYEPKPDKAAanhYLNKKPGFYLSEEAFVDELRRVLGMRPGT-----RHPVAYIMEAADDIS 260
Cdd:PRK01096 172 gmRLTYATLGTYIKY--PWSSRHANKQQ---IKKKKFGCYQSELPLFEQIAEALGLPQLGeqrwcRHPLTYLLEAADDIC 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 261 YCLADIEDSVEKGILDIRQLADLLVkkfavhhspdaPIPGDADnmsfqRMVDYSLEKAEREPINkvseffiRLRVKMIHP 340
Cdd:PRK01096 247 YALIDLEDGLEMGLLNYQEVEALFL-----------ELIGDKE-----KYRQLGPQDSRRQKLA-------RLRGKAIGR 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 341 LVQHAAQQFIDNFEAVHAGTLGRALME--DGSLpHAIVQTFKDVAMEWVFCHPEVETLELQGYRIIQGLLDFYAPllrlp 418
Cdd:PRK01096 304 LVNAVAEAFVENYDAILAGTLPGDLIEhcDPDA-KRCVQQAKDLAREKIFQHKRKVELEIGAYTILEILLDAFVP----- 377
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15596321 419 aeefqalaegrqaaAPHPQLLVRRLPSQQiKAYLEAMKGVAEDPlqrQWEFYHRCRMLQDFVSGMTDQHAQDEYRALS 496
Cdd:PRK01096 378 --------------AALYYDSGTTPSFKD-KRLLDLLGDNAPDP---TMKLYLRLLRVLDFISGMTDSYAKELAQELT 437
|
|
| PRK05318 |
PRK05318 |
deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional |
17-495 |
4.93e-44 |
|
deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional
Pssm-ID: 235403 [Multi-domain] Cd Length: 432 Bit Score: 160.81 E-value: 4.93e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 17 HDRETYGHAGNTDLQDIVYQleSDRGRIVNSAAVRRLQQKTQVFPLERNAAVRSRLTHSLEVQQTGRFIVRTLFRQLGPR 96
Cdd:PRK05318 7 QERRLGEDKQRRNDHRSPYQ--RDRARILHSAAFRRLQAKTQVLGVGENDFYRTRLTHSLEVAQIGTGIVAQLKKEKQPE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 97 aaevgldgLEGALES--LVEMACLMHDVGNPPFGHFGEYAINdwfernldalferrippgqgdgllqqRMLTDLKHFEGN 174
Cdd:PRK05318 85 --------LKPLLPSdsLIESLCLAHDIGHPPFGHGGEVALN--------------------------YMMRDHGGFEGN 130
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 175 AQAIRLVVKL------LRLNLTYTQTAGLLKYvrPA-----YEPKPDKAAANHYLNK----KP--GFYLSEEAFVDEL-- 235
Cdd:PRK05318 131 GQTFRILTKLepytehFGMNLTRRTLLGILKY--PAlyselVAQYPPPDVANHRQLKasdwKPpkGIFDDDQDIFDWVle 208
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 236 ------------RRVLGMRPGTRHPVAY------IMEAADDISYCLADIEDSVEKGILDIRQLADLLVKKFAvhHSPDAP 297
Cdd:PRK05318 209 plsendralfqsLRPEPDSPKEHLKTRYksldcsIMELADDIAYGVHDLEDAIVLGLVTRSQWQEDVAPQLA--QCGDPW 286
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 298 IPGDADNMSfQRMvdYSLEKAER-EPINK-VSEFFIRLRVKMI----HPLVQHAAqQFIDNFEAVhagtlgralmedgsl 371
Cdd:PRK05318 287 LEEEIETIG-EKL--FSGEHHLRkDAIGTlVNYFITSIRIKENeefeEPLLRYNA-ALEPEFAAA--------------- 347
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 372 phaiVQTFKDVAMEWVFCHPEVETLELQGYRIIQGLldfyapllrlpaeeFQALAEGrqaaaphPQllvRRLPSQQIKAY 451
Cdd:PRK05318 348 ----LEVLKQFVYKYVIRKPEVQRLEYKGQQIVMEL--------------FEALSSD-------PE---RLLPRNTQERW 399
|
490 500 510 520
....*....|....*....|....*....|....*....|....
gi 15596321 452 LEamkgvAEDPLQRQwefyhrcRMLQDFVSGMTDQHAQDEYRAL 495
Cdd:PRK05318 400 RK-----AEDEENSM-------RVICDYISGMTDEYAYRLYQQL 431
|
|
| PRK03007 |
PRK03007 |
deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional |
40-283 |
2.71e-34 |
|
deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional
Pssm-ID: 235098 [Multi-domain] Cd Length: 428 Bit Score: 133.53 E-value: 2.71e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 40 DRGRIVNSAAVRRLQQKTQVF-PLERNAAvRSRLTHSLEVQQTGRFIvrtlfrqlgprAAEVGLDglegalESLVEMACL 118
Cdd:PRK03007 40 DRARVLHSAALRRLADKTQVVgPREGDTP-RTRLTHSLEVAQIGRGI-----------AAGLGCD------PDLVDLAGL 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 119 MHDVGNPPFGHFGEYAINDWfernldalferrippgqgdgllqqrmLTDLKHFEGNAQAIRLVVKL-----------LRL 187
Cdd:PRK03007 102 AHDIGHPPYGHNGERALDEV--------------------------AADCGGFEGNAQTLRILTRLepkvldpdgrsAGL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 188 NLTYTQTAGLLKYVRPAYEPKPDKaaanhylNKKPGFYLSEEAFVDELRRvlgMRPGTRHPV-AYIMEAADDISYCLADI 266
Cdd:PRK03007 156 NLTRASLDAACKYPWTRGEADGSP-------RRKFGFYDDDREVFAWVRQ---GAPAGRPCLeAQVMDWADDVAYSVHDV 225
|
250
....*....|....*..
gi 15596321 267 EDSVEKGILDIRQLADL 283
Cdd:PRK03007 226 EDGVVSGRIDLRVLADP 242
|
|
| PRK01286 |
PRK01286 |
deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional |
40-495 |
2.19e-23 |
|
deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional
Pssm-ID: 234934 [Multi-domain] Cd Length: 336 Bit Score: 101.01 E-value: 2.19e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 40 DRGRIVNSAAVRRLQQKTQVFPLERNAAVRSRLTHSLEVQQTGRFIVRTLfrqlgpraaevGLDglegalESLVEMACLM 119
Cdd:PRK01286 32 DRDRIIHSKAFRRLKHKTQVFINPEGDHYRTRLTHTLEVAQIARTIARAL-----------RLN------EDLTEAIALG 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 120 HDVGNPPFGHFGEYAINdwfernldalfeRRIPPGQGdgllqqrmltdlkhFEGNAQAIRLVVKLLR----LNLTYTQTA 195
Cdd:PRK01286 95 HDLGHTPFGHAGEDALN------------ELMKEYGG--------------FEHNEQSLRVVDKLEKrydgLNLTWEVRE 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 196 GLLKYVRPayepkpdkaaanhyLNKKPGFYLSEEAFVdelrrvlgmrpgtrhpVAYimeaADDISYCLADIEDSVEKGIL 275
Cdd:PRK01286 149 GILKHSGP--------------RNAPLGTAATLEGQI----------------VRL----ADEIAYNNHDIDDGIRAGLI 194
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 276 DIRQLADLLVKkfAVHHSPdapipgdadnmsfqrmvdyslekaeREPINkvseffirlrvKMIHPLVQHAaqqfIDNFEA 355
Cdd:PRK01286 195 TLEDLPEDVRR--LLGETH-------------------------RRRIN-----------TLVVDLIKNT----QRNLAE 232
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 356 VHAGTlGRALMEDGSlpHAIVQTFKDVAMEWVFCHPEVETLELQGYRIIQGLLDFYapllrlpaeefqaLAegrqaaapH 435
Cdd:PRK01286 233 GAAAP-PLVSFSEEV--AEAMKELRRFLFENVYRHPKVKREREKAKRIVQDLFEYY-------------ME--------D 288
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 436 PQLlvrrLPSQqikayleamkgvaedpLQRQWEFYHRCRMLQDFVSGMTDQHAQDEYRAL 495
Cdd:PRK01286 289 PEL----LPPE----------------YQNIAEEEGLERAVADYIAGMTDRYALREYRRL 328
|
|
| HDc |
smart00471 |
Metal dependent phosphohydrolases with conserved 'HD' motif; Includes eukaryotic cyclic ... |
67-140 |
5.83e-04 |
|
Metal dependent phosphohydrolases with conserved 'HD' motif; Includes eukaryotic cyclic nucleotide phosphodiesterases (PDEc). This profile/HMM does not detect HD homologues in bacterial glycine aminoacyl-tRNA synthetases (beta subunit).
Pssm-ID: 214679 [Multi-domain] Cd Length: 124 Bit Score: 39.97 E-value: 5.83e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15596321 67 AVRSRLTHSLEVQQTGRFIvrtlfrqlgprAAEVGLDGLEgalesLVEMACLMHDVGNPPFGHFGEYAINDWFE 140
Cdd:smart00471 1 SDYHVFEHSLRVAQLAAAL-----------AEELGLLDIE-----LLLLAALLHDIGKPGTPDSFLVKTSVLED 58
|
|
| HD |
pfam01966 |
HD domain; HD domains are metal dependent phosphohydrolases. |
71-129 |
4.36e-03 |
|
HD domain; HD domains are metal dependent phosphohydrolases.
Pssm-ID: 460398 [Multi-domain] Cd Length: 110 Bit Score: 36.83 E-value: 4.36e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 15596321 71 RLTHSLEVQQtgrfIVRTLFRQLGPRAAEvgldglegalesLVEMACLMHDVGNPPFGH 129
Cdd:pfam01966 1 RLEHSLRVAL----LARELAEELGELDRE------------LLLLAALLHDIGKGPFGD 43
|
|
| HDc |
cd00077 |
Metal dependent phosphohydrolases with conserved 'HD' motif |
69-135 |
6.76e-03 |
|
Metal dependent phosphohydrolases with conserved 'HD' motif
Pssm-ID: 238032 [Multi-domain] Cd Length: 145 Bit Score: 37.32 E-value: 6.76e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15596321 69 RSRLTHSLEVQQTGRFIVRTLfrqlgpraaevgldGLEGALESLVEMACLMHDVGNPPFGHFGEYAI 135
Cdd:cd00077 1 EHRFEHSLRVAQLARRLAEEL--------------GLSEEDIELLRLAALLHDIGKPGTPDAITEEE 53
|
|
| HD_assoc |
pfam13286 |
Phosphohydrolase-associated domain; This domain is found on bacterial and archaeal ... |
380-493 |
9.81e-03 |
|
Phosphohydrolase-associated domain; This domain is found on bacterial and archaeal metal-dependent phosphohydrolases.
Pssm-ID: 433087 [Multi-domain] Cd Length: 91 Bit Score: 35.58 E-value: 9.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596321 380 KDVAMEWVFCHPEVETLELQGYRIIQGLLDFYA--PLLrLPaEEFQALAEGRQAAAPHpqllvrrlpsqqikayleamkg 457
Cdd:pfam13286 15 KRFLFEYVYRHPRVQREEEKARRIIRELFEALMadPEL-LP-PEFRARWEAAGDDARA---------------------- 70
|
90 100 110
....*....|....*....|....*....|....*.
gi 15596321 458 vaedplqrqwefyhrcRMLQDFVSGMTDQHAQDEYR 493
Cdd:pfam13286 71 ----------------RVVCDYIAGMTDRYALRLHR 90
|
|
|