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Conserved domains on  [gi|15596915|ref|NP_250409|]
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type III export protein PscE [Pseudomonas aeruginosa PAO1]

Protein Classification

EscE/YscE/SsaE family type III secretion system needle protein co-chaperone( domain architecture ID 10020795)

EscE/YscE/SsaE family type III secretion system (T3SS) needle protein co-chaperone functions in stabilizing the T3SS needle prior to secretion

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
type_III_yscE TIGR02501
type III secretion system protein, YseE family; Members of this family are found exclusively ...
 2-67 4.42e-16

type III secretion system protein, YseE family; Members of this family are found exclusively in type III secretion appparatus gene clusters in bacteria. Those bacteria with a protein from this family tend to target animal cells, as does Yersinia pestis. This protein is small (about 70 amino acids) and not well characterized. [Cellular processes, Pathogenesis]


:

Pssm-ID: 274167  Cd Length: 67  Bit Score: 65.06  E-value: 4.42e-16
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15596915    2 MTALETRLSVADGThAAALRQRLQAALAECRRELARGACPEHFQFLQQQARALEGGLGILSQLTED 67
Cdd:TIGR02501  1 MTQLEDRLSHADTA-ARAIIEQLEAALAELKEQLSRGGDPQQYQEWQLLADAIEAAIKIIEILTGR 65
 
Name Accession Description Interval E-value
type_III_yscE TIGR02501
type III secretion system protein, YseE family; Members of this family are found exclusively ...
 2-67 4.42e-16

type III secretion system protein, YseE family; Members of this family are found exclusively in type III secretion appparatus gene clusters in bacteria. Those bacteria with a protein from this family tend to target animal cells, as does Yersinia pestis. This protein is small (about 70 amino acids) and not well characterized. [Cellular processes, Pathogenesis]


Pssm-ID: 274167  Cd Length: 67  Bit Score: 65.06  E-value: 4.42e-16
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15596915    2 MTALETRLSVADGThAAALRQRLQAALAECRRELARGACPEHFQFLQQQARALEGGLGILSQLTED 67
Cdd:TIGR02501  1 MTQLEDRLSHADTA-ARAIIEQLEAALAELKEQLSRGGDPQQYQEWQLLADAIEAAIKIIEILTGR 65
T3SS_needle_E pfam08988
Type III secretion system, cytoplasmic E component of needle; T3SS_needle_E is a family of ...
 2-67 3.31e-15

Type III secretion system, cytoplasmic E component of needle; T3SS_needle_E is a family of proteins from the operon that builds and controls the needle of the injection system of type III secretion. The YscE protein, produced by the pathogen Yersinia, assumes a secondary structure composed of two anti-parallel alpha-helices separated by a flexible loop. The family is cytoplasmic and may help to stabilize and prevent early polymerization of the needle-protein F.


Pssm-ID: 430358  Cd Length: 66  Bit Score: 62.76  E-value: 3.31e-15
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15596915    2 MTALETRLSVADgTHAAALRQRLQAALAECRRELARGACPEHFQFLQQQARALEGGLGILSQLTED 67
Cdd:pfam08988  1 ITALEDRLKNDP-EHAKAILQRLEAALAQLKQQLSRGQTPERYQQLQLLADALESAEGIINILTYR 65
 
Name Accession Description Interval E-value
type_III_yscE TIGR02501
type III secretion system protein, YseE family; Members of this family are found exclusively ...
 2-67 4.42e-16

type III secretion system protein, YseE family; Members of this family are found exclusively in type III secretion appparatus gene clusters in bacteria. Those bacteria with a protein from this family tend to target animal cells, as does Yersinia pestis. This protein is small (about 70 amino acids) and not well characterized. [Cellular processes, Pathogenesis]


Pssm-ID: 274167  Cd Length: 67  Bit Score: 65.06  E-value: 4.42e-16
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15596915    2 MTALETRLSVADGThAAALRQRLQAALAECRRELARGACPEHFQFLQQQARALEGGLGILSQLTED 67
Cdd:TIGR02501  1 MTQLEDRLSHADTA-ARAIIEQLEAALAELKEQLSRGGDPQQYQEWQLLADAIEAAIKIIEILTGR 65
T3SS_needle_E pfam08988
Type III secretion system, cytoplasmic E component of needle; T3SS_needle_E is a family of ...
 2-67 3.31e-15

Type III secretion system, cytoplasmic E component of needle; T3SS_needle_E is a family of proteins from the operon that builds and controls the needle of the injection system of type III secretion. The YscE protein, produced by the pathogen Yersinia, assumes a secondary structure composed of two anti-parallel alpha-helices separated by a flexible loop. The family is cytoplasmic and may help to stabilize and prevent early polymerization of the needle-protein F.


Pssm-ID: 430358  Cd Length: 66  Bit Score: 62.76  E-value: 3.31e-15
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15596915    2 MTALETRLSVADgTHAAALRQRLQAALAECRRELARGACPEHFQFLQQQARALEGGLGILSQLTED 67
Cdd:pfam08988  1 ITALEDRLKNDP-EHAKAILQRLEAALAQLKQQLSRGQTPERYQQLQLLADALESAEGIINILTYR 65
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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