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Conserved domains on  [gi|15597011|ref|NP_250505|]
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hypothetical protein PA1814 [Pseudomonas aeruginosa PAO1]

Protein Classification

class I SAM-dependent methyltransferase( domain architecture ID 106779)

class I SAM-dependent methyltransferase catalyzes the methylation of one or more specific substrates using S-adenosyl-L-methionine (SAM or AdoMet) as the methyl donor

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Methyltransf_11 super family cl48003
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
92-132 7.58e-07

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


The actual alignment was detected with superfamily member pfam08241:

Pssm-ID: 462406 [Multi-domain]  Cd Length: 94  Bit Score: 46.12  E-value: 7.58e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 15597011    92 PLSEHAADVVLLQHGLDFCLSPHRLLREAARTVRPGGHLLL 132
Cdd:pfam08241  54 PFPDNSFDLVLSSEVLHHVEDPERALREIARVLKPGGILII 94
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
64-148 1.09e-06

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


:

Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 46.91  E-value: 1.09e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597011  64 PSTGQIQRGVRLGPPLpGVDIACEEG---AWPLSEHAADVVLLQHGLDFCLSPHRLLREAARTVRPGGHLLLIGINPWSL 140
Cdd:COG2226  52 ISPEMLELARERAAEA-GLNVEFVVGdaeDLPFPDGSFDLVISSFVLHHLPDPERALAEIARVLKPGGRLVVVDFSPPDL 130

                ....*...
gi 15597011 141 WGIRHYFA 148
Cdd:COG2226 131 AELEELLA 138
 
Name Accession Description Interval E-value
Methyltransf_11 pfam08241
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
92-132 7.58e-07

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 462406 [Multi-domain]  Cd Length: 94  Bit Score: 46.12  E-value: 7.58e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 15597011    92 PLSEHAADVVLLQHGLDFCLSPHRLLREAARTVRPGGHLLL 132
Cdd:pfam08241  54 PFPDNSFDLVLSSEVLHHVEDPERALREIARVLKPGGILII 94
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
64-148 1.09e-06

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 46.91  E-value: 1.09e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597011  64 PSTGQIQRGVRLGPPLpGVDIACEEG---AWPLSEHAADVVLLQHGLDFCLSPHRLLREAARTVRPGGHLLLIGINPWSL 140
Cdd:COG2226  52 ISPEMLELARERAAEA-GLNVEFVVGdaeDLPFPDGSFDLVISSFVLHHLPDPERALAEIARVLKPGGRLVVVDFSPPDL 130

                ....*...
gi 15597011 141 WGIRHYFA 148
Cdd:COG2226 131 AELEELLA 138
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
90-132 1.13e-03

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 38.07  E-value: 1.13e-03
                        10        20        30        40
                ....*....|....*....|....*....|....*....|...
gi 15597011  90 AWPLSEHAADVVLLQHGLDFCLSPHRLLREAARTVRPGGHLLL 132
Cdd:COG2227  80 DLPLEDGSFDLVICSEVLEHLPDPAALLRELARLLKPGGLLLL 122
 
Name Accession Description Interval E-value
Methyltransf_11 pfam08241
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
92-132 7.58e-07

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 462406 [Multi-domain]  Cd Length: 94  Bit Score: 46.12  E-value: 7.58e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 15597011    92 PLSEHAADVVLLQHGLDFCLSPHRLLREAARTVRPGGHLLL 132
Cdd:pfam08241  54 PFPDNSFDLVLSSEVLHHVEDPERALREIARVLKPGGILII 94
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
64-148 1.09e-06

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 46.91  E-value: 1.09e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597011  64 PSTGQIQRGVRLGPPLpGVDIACEEG---AWPLSEHAADVVLLQHGLDFCLSPHRLLREAARTVRPGGHLLLIGINPWSL 140
Cdd:COG2226  52 ISPEMLELARERAAEA-GLNVEFVVGdaeDLPFPDGSFDLVISSFVLHHLPDPERALAEIARVLKPGGRLVVVDFSPPDL 130

                ....*...
gi 15597011 141 WGIRHYFA 148
Cdd:COG2226 131 AELEELLA 138
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
90-132 1.13e-03

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 38.07  E-value: 1.13e-03
                        10        20        30        40
                ....*....|....*....|....*....|....*....|...
gi 15597011  90 AWPLSEHAADVVLLQHGLDFCLSPHRLLREAARTVRPGGHLLL 132
Cdd:COG2227  80 DLPLEDGSFDLVICSEVLEHLPDPAALLRELARLLKPGGLLLL 122
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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