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Conserved domains on  [gi|15597327|ref|NP_250821|]
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fimbrial subunit CupA4 [Pseudomonas aeruginosa PAO1]

Protein Classification

fimbrial protein( domain architecture ID 646)

fimbrial protein similar to the type-1 fimbrial major subunit FimA, which is transported to the outer membrane by the lipoprotein sorting system, and a mature or processed FimA protein on the outer membrane is autopolymerized to form Fim fimbriae

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Fimbrial super family cl01416
Fimbrial protein;
25-453 7.37e-85

Fimbrial protein;


The actual alignment was detected with superfamily member PRK15247:

Pssm-ID: 445401  Cd Length: 441  Bit Score: 267.15  E-value: 7.37e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597327   25 ATCYRVTSVGSettTSNTQIRPGEgTAGSWTGACDTCNGSLGLPSVVNVSD-ESFQPYPTLIASAVAPLTQYGATGGYDP 103
Cdd:PRK15247  22 SSCIKVTDKSA---LSDAAIKAGY-TAQNWIGATDTNTGNIGLPTVISVSNsETFQPSGTLLASGIGNFLTAATGTPYSS 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597327  104 ERVFFRCSAGDA--VYEMFSTNGDDLYSGyytgadtvGNDI-GLQDAYRTAWPNVLLRLTNVETGETITPIWKERQLSGL 180
Cdd:PRK15247  98 KQVLYRCDSADAgkLYEMYSTNGDSAFAG--------AFFTpEVEGAYYDVERNVAVRMTNLSTGEYYSRFWKERQLTAD 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597327  181 DIDSRG-FQLVKAKNLAAVRAELYSapLEAIRYYSPTILSQPYSYTQPAAYIAIKGPGLTAPTV--GQAHvGGNWGGWYS 257
Cdd:PRK15247 170 SWFQDDkYIYIPASAFSNVLYEMFK--IDSRKYFAYQNPMDRDTWTQPRGYIAFKGPGLITERIkaGLDH-ASDYYGWPS 246

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597327  258 NWPGAIGLYRYVTLKRYPTCAVMTVTPHVQFPSITLAEIDSGGVREAPFELTFKCQSGMTNG----TGAGATALGIRVSS 333
Cdd:PRK15247 247 YWPGAWSTYNSVTYVRGALCKITDYPAIVKIPPVAVGILAAGGNSQAPFHVSLECESGAVSSalpsTSAANVAMGFVVNQ 326

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597327  334 -GALAASPALGLVNASGGLSYLLSDRYGEPGIARGVGIRIYRD-GTPMTLLANENSAGGSNAEatGWYPAIGGATQAngG 411
Cdd:PRK15247 327 pTAVAAARRLGLTTSAGGLSWLLDTHYGEPGVASGVGIRIYNDaGTPINLLPDRIKTGTGNAR--GWYGYKDLTTRV--S 402

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|..
gi 15597327  412 SGGIDLYRETFRARLEklALGSQpGVTAGRVEATAQVVIRVQ 453
Cdd:PRK15247 403 SGSVETYSGDFTASLE--AIGGQ-TVTAGSVNAQLQAVVSFQ 441
 
Name Accession Description Interval E-value
PRK15247 PRK15247
fimbrial usher protein StbD;
25-453 7.37e-85

fimbrial usher protein StbD;


Pssm-ID: 185159  Cd Length: 441  Bit Score: 267.15  E-value: 7.37e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597327   25 ATCYRVTSVGSettTSNTQIRPGEgTAGSWTGACDTCNGSLGLPSVVNVSD-ESFQPYPTLIASAVAPLTQYGATGGYDP 103
Cdd:PRK15247  22 SSCIKVTDKSA---LSDAAIKAGY-TAQNWIGATDTNTGNIGLPTVISVSNsETFQPSGTLLASGIGNFLTAATGTPYSS 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597327  104 ERVFFRCSAGDA--VYEMFSTNGDDLYSGyytgadtvGNDI-GLQDAYRTAWPNVLLRLTNVETGETITPIWKERQLSGL 180
Cdd:PRK15247  98 KQVLYRCDSADAgkLYEMYSTNGDSAFAG--------AFFTpEVEGAYYDVERNVAVRMTNLSTGEYYSRFWKERQLTAD 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597327  181 DIDSRG-FQLVKAKNLAAVRAELYSapLEAIRYYSPTILSQPYSYTQPAAYIAIKGPGLTAPTV--GQAHvGGNWGGWYS 257
Cdd:PRK15247 170 SWFQDDkYIYIPASAFSNVLYEMFK--IDSRKYFAYQNPMDRDTWTQPRGYIAFKGPGLITERIkaGLDH-ASDYYGWPS 246

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597327  258 NWPGAIGLYRYVTLKRYPTCAVMTVTPHVQFPSITLAEIDSGGVREAPFELTFKCQSGMTNG----TGAGATALGIRVSS 333
Cdd:PRK15247 247 YWPGAWSTYNSVTYVRGALCKITDYPAIVKIPPVAVGILAAGGNSQAPFHVSLECESGAVSSalpsTSAANVAMGFVVNQ 326

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597327  334 -GALAASPALGLVNASGGLSYLLSDRYGEPGIARGVGIRIYRD-GTPMTLLANENSAGGSNAEatGWYPAIGGATQAngG 411
Cdd:PRK15247 327 pTAVAAARRLGLTTSAGGLSWLLDTHYGEPGVASGVGIRIYNDaGTPINLLPDRIKTGTGNAR--GWYGYKDLTTRV--S 402

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|..
gi 15597327  412 SGGIDLYRETFRARLEklALGSQpGVTAGRVEATAQVVIRVQ 453
Cdd:PRK15247 403 SGSVETYSGDFTASLE--AIGGQ-TVTAGSVNAQLQAVVSFQ 441
Fimbrial pfam00419
Fimbrial protein;
263-453 1.01e-17

Fimbrial protein;


Pssm-ID: 425671  Cd Length: 152  Bit Score: 79.79  E-value: 1.01e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597327   263 IGLYRYVTlKRYPTCAVMTVTP-HVQFPSITLAEIDSGGV--REAPFELTFKCQSGMTngtgagATALGIRVSSGALAAS 339
Cdd:pfam00419   1 INFTGTVT-RVPATCKITAGTPiEVDFGQIPVNELNAGGEgsRQKPFSITLECSSGSS------AVKVTVGLFGTADASS 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597327   340 PALgLVNASGGlsyllsdrygepGIARGVGIRIYRDGTPMTLLANENSAggsnaeatgwypAIGGATQANGGSGgidlyr 419
Cdd:pfam00419  74 PNL-LLTGNGA------------GAATGVGIRLYDANGGALPPNNGTSS------------IPVSATAAVATGI------ 122

                         170       180       190
                  ....*....|....*....|....*....|....
gi 15597327   420 eTFRARLEKLALGSqpgVTAGRVEATAQVVIRVQ 453
Cdd:pfam00419 123 -TFTASLVATTGGT---PTAGDFNATATIVVDYQ 152
FimA COG3539
Pilin (type 1 fimbrial protein) [Cell motility];
275-450 4.17e-04

Pilin (type 1 fimbrial protein) [Cell motility];


Pssm-ID: 442760 [Multi-domain]  Cd Length: 172  Bit Score: 41.18  E-value: 4.17e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597327 275 PTCAVMTVTPH--VQFPSITLAEIDSGG--VREAPFELTFkcqsgmTNGTGAGATALGIRVSSGALAASPALGLVNASGG 350
Cdd:COG3539  35 PTCTINTGSKDqtVDLGTVSTSDLNGVGstSGPKPFSIKL------TNCDAGTSNSVKVTFTGTADSANPGLLANTGSGG 108

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597327 351 lsyllsdrygepgiARGVGIRIY-RDGTPMTLlaNENSAggsnaeatgwypaiggaTQANGGSGGIDLyreTFRARLEKL 429
Cdd:COG3539 109 --------------ASGVGIQLLdSDGTPIPL--GTPSS-----------------AVTLTSNGSATL---PFYARYVAT 152

                       170       180
                ....*....|....*....|.
gi 15597327 430 AlgsqPGVTAGRVEATAQVVI 450
Cdd:COG3539 153 G----ATVTAGSFNATATFTI 169
 
Name Accession Description Interval E-value
PRK15247 PRK15247
fimbrial usher protein StbD;
25-453 7.37e-85

fimbrial usher protein StbD;


Pssm-ID: 185159  Cd Length: 441  Bit Score: 267.15  E-value: 7.37e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597327   25 ATCYRVTSVGSettTSNTQIRPGEgTAGSWTGACDTCNGSLGLPSVVNVSD-ESFQPYPTLIASAVAPLTQYGATGGYDP 103
Cdd:PRK15247  22 SSCIKVTDKSA---LSDAAIKAGY-TAQNWIGATDTNTGNIGLPTVISVSNsETFQPSGTLLASGIGNFLTAATGTPYSS 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597327  104 ERVFFRCSAGDA--VYEMFSTNGDDLYSGyytgadtvGNDI-GLQDAYRTAWPNVLLRLTNVETGETITPIWKERQLSGL 180
Cdd:PRK15247  98 KQVLYRCDSADAgkLYEMYSTNGDSAFAG--------AFFTpEVEGAYYDVERNVAVRMTNLSTGEYYSRFWKERQLTAD 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597327  181 DIDSRG-FQLVKAKNLAAVRAELYSapLEAIRYYSPTILSQPYSYTQPAAYIAIKGPGLTAPTV--GQAHvGGNWGGWYS 257
Cdd:PRK15247 170 SWFQDDkYIYIPASAFSNVLYEMFK--IDSRKYFAYQNPMDRDTWTQPRGYIAFKGPGLITERIkaGLDH-ASDYYGWPS 246

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597327  258 NWPGAIGLYRYVTLKRYPTCAVMTVTPHVQFPSITLAEIDSGGVREAPFELTFKCQSGMTNG----TGAGATALGIRVSS 333
Cdd:PRK15247 247 YWPGAWSTYNSVTYVRGALCKITDYPAIVKIPPVAVGILAAGGNSQAPFHVSLECESGAVSSalpsTSAANVAMGFVVNQ 326

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597327  334 -GALAASPALGLVNASGGLSYLLSDRYGEPGIARGVGIRIYRD-GTPMTLLANENSAGGSNAEatGWYPAIGGATQAngG 411
Cdd:PRK15247 327 pTAVAAARRLGLTTSAGGLSWLLDTHYGEPGVASGVGIRIYNDaGTPINLLPDRIKTGTGNAR--GWYGYKDLTTRV--S 402

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|..
gi 15597327  412 SGGIDLYRETFRARLEklALGSQpGVTAGRVEATAQVVIRVQ 453
Cdd:PRK15247 403 SGSVETYSGDFTASLE--AIGGQ-TVTAGSVNAQLQAVVSFQ 441
Fimbrial pfam00419
Fimbrial protein;
263-453 1.01e-17

Fimbrial protein;


Pssm-ID: 425671  Cd Length: 152  Bit Score: 79.79  E-value: 1.01e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597327   263 IGLYRYVTlKRYPTCAVMTVTP-HVQFPSITLAEIDSGGV--REAPFELTFKCQSGMTngtgagATALGIRVSSGALAAS 339
Cdd:pfam00419   1 INFTGTVT-RVPATCKITAGTPiEVDFGQIPVNELNAGGEgsRQKPFSITLECSSGSS------AVKVTVGLFGTADASS 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597327   340 PALgLVNASGGlsyllsdrygepGIARGVGIRIYRDGTPMTLLANENSAggsnaeatgwypAIGGATQANGGSGgidlyr 419
Cdd:pfam00419  74 PNL-LLTGNGA------------GAATGVGIRLYDANGGALPPNNGTSS------------IPVSATAAVATGI------ 122

                         170       180       190
                  ....*....|....*....|....*....|....
gi 15597327   420 eTFRARLEKLALGSqpgVTAGRVEATAQVVIRVQ 453
Cdd:pfam00419 123 -TFTASLVATTGGT---PTAGDFNATATIVVDYQ 152
FimA COG3539
Pilin (type 1 fimbrial protein) [Cell motility];
275-450 4.17e-04

Pilin (type 1 fimbrial protein) [Cell motility];


Pssm-ID: 442760 [Multi-domain]  Cd Length: 172  Bit Score: 41.18  E-value: 4.17e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597327 275 PTCAVMTVTPH--VQFPSITLAEIDSGG--VREAPFELTFkcqsgmTNGTGAGATALGIRVSSGALAASPALGLVNASGG 350
Cdd:COG3539  35 PTCTINTGSKDqtVDLGTVSTSDLNGVGstSGPKPFSIKL------TNCDAGTSNSVKVTFTGTADSANPGLLANTGSGG 108

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597327 351 lsyllsdrygepgiARGVGIRIY-RDGTPMTLlaNENSAggsnaeatgwypaiggaTQANGGSGGIDLyreTFRARLEKL 429
Cdd:COG3539 109 --------------ASGVGIQLLdSDGTPIPL--GTPSS-----------------AVTLTSNGSATL---PFYARYVAT 152

                       170       180
                ....*....|....*....|.
gi 15597327 430 AlgsqPGVTAGRVEATAQVVI 450
Cdd:COG3539 153 G----ATVTAGSFNATATFTI 169
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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