|
Name |
Accession |
Description |
Interval |
E-value |
| FtsI |
COG0768 |
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ... |
1-548 |
0e+00 |
|
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain] Cd Length: 568 Bit Score: 580.24 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 1 MSSQRR----NYRFILVVTLFVLASLAVSGRLVYLQVHDHEFLADQGDLRSIRDLPIPVTRGMITDRNGEPLAVSTEVAS 76
Cdd:COG0768 1 MKRKKEkrlfRRRLLLLFLLVLLLFLLLVGRLFYLQVVEGDEYAELAEENRIRTVPIPAPRGLIYDRNGNVLATNVPVYS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 77 IWCNPREMAAHLDEVPRLAGALHRPAAALLAQLqaNPNKRF-LYLERGLSPIEASEVMALGITGVHQIKEYKRFYPSSEL 155
Cdd:COG0768 81 LYADPEEVKDPEETAEKLAKLLGLDPEELRKKL--KKKSRFpVYLKRNLSPEEAARIRALKLPGVYVEAEYKRYYPYGEL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 156 TAQLIGLVNI----DGRGQEGTELGFNDWLSGKDGVREVAINPRGSLVNSIKVLKTPKASQDVALSIDLRLQFIAYKALE 231
Cdd:COG0768 159 AAHVLGYVGEinggDGIGKSGLEKAYEDLLRGTPGKRRVEVDARGRVIRDLGEEKPPVPGKDLVLTIDSDLQKIAEEALK 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 232 KAVLKFGAHSGSAVLVNPKSGQILAMANFPSYNPNNRASFAPAFMRNRTLTDTFEPGSVIKPFSMSAALASGKFDENSQV 311
Cdd:COG0768 239 KAVEEYKAKSGAVVVMDPKTGEILAMASYPSFDPNLFVGGPDEPLRNRAVQGTYEPGSTFKPFTAAAALEEGVITPDTTF 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 312 SVaPGWMTIDGHTIHDVARRD--VLTMTGVLINSSNIGMSKVALQIGPKPILEQLGRVGFGAPLSLGFPGENPGYLPFHE 389
Cdd:COG0768 319 DC-PGYYRVGGRTIRDWDRGGhgTLTLTEALAKSSNVGFYKLALRLGIDKLYDYLKKFGLGQKTGIDLPGEASGLLPSPK 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 390 KWSNIATASMSFGYSLAVNTAELAQAYSVFANDGKLVPLSLLRD--NPQNQV--------RQAMDPQIARRIRAMLQTVV 459
Cdd:COG0768 398 RWYPGETATMSIGQGLSVTPLQLAQAYAAIANGGVLVKPHLVKEivDPDGEVvkeepevlRRVISPETAETVREGMEGVV 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 460 EDPKGV-VRARVPGYHVAGKSGTARKAS--GRGYADKSYRSLFVGMAPASDPQLVLAVMIDSPTRiGYFGGLVSAPTFSD 536
Cdd:COG0768 478 NEPGGTaRRAAIPGYRVAGKTGTAQVVDigNGGYYKGRHIASFVGFAPADNPRYAVAVVVENPGG-GAYGGTVAAPVFRE 556
|
570
....*....|..
gi 15597468 537 IMAGSLRALAIP 548
Cdd:COG0768 557 IMEAYLRLLGPP 568
|
|
| PRK15105 |
PRK15105 |
peptidoglycan synthase FtsI; Provisional |
7-552 |
9.91e-149 |
|
peptidoglycan synthase FtsI; Provisional
Pssm-ID: 185060 [Multi-domain] Cd Length: 578 Bit Score: 440.03 E-value: 9.91e-149
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 7 NYRFILVVTLFVLASLAVSGRLVYLQVHDHEFLADQGDLRSIRDLPIPVTRGMITDRNGEPLAVSTEVASIWCNPREMAA 86
Cdd:PRK15105 20 SWRFALLCGCILLALVFLLGRVAWLQVINPDMLVREGDMRSLRVQEVSTSRGMITDRSGRPLAVSVPVKAIWADPKEVHD 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 87 H----LDEVPR-LAGALHRPAAALLAQLQANPNKRFLYLERGLSPIEASEVMALGITGVHQIKEYKRFYPSSELTAQLIG 161
Cdd:PRK15105 100 AggisVDDRWKaLADALNIPLDQLSARINANPKGRFIYLARQVNPDMADYIKKLKLPGIHLREESRRYYPSGEVTAHLIG 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 162 LVNIDGRGQEGTELGFNDWLSGKDGVREVAINPRGSLVNSIKVLKTpKASQDVALSIDLRLQFIAYKALEKAVLKFGAHS 241
Cdd:PRK15105 180 FTNVDSQGIEGVEKSFDKWLTGQPGERIVRKDRYGRVIEDISSTDS-QAAHNLALSIDERLQALVYRELNNAVAFNKAES 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 242 GSAVLVNPKSGQILAMANFPSYNPNNRASFAPAFMRNRTLTDTFEPGSVIKPFSMSAALASGKFDENSQVSVAPgwMTID 321
Cdd:PRK15105 259 GSAVLVDVNTGEVLAMANSPSYNPNNLSGTPKDAMRNRAITDVFEPGSTVKPMVVMTALQRGVVKENSVLNTVP--YRIN 336
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 322 GHTIHDVARRDVLTMTGVLINSSNIGMSKVALQIGPKPILEQLGRVGFGAPLSLGFPGENPGYLPFHEKWSNIATASMSF 401
Cdd:PRK15105 337 GHEIKDVARYSELTLTGVLQKSSNVGVSKLALAMPSSALVDTYSRFGLGKATNLGLVGERSGLYPQKQRWSDIERATFSF 416
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 402 GYSLAVNTAELAQAYSVFANDGKLVPLSLLRDNPQNQVRQAMDPQIARRIRAMLQTVVEDPKGVVRARVPGYHVAGKSGT 481
Cdd:PRK15105 417 GYGLMVTPLQLARVYATIGSYGIYRPLSITKVDPPVPGERVFPESIVRTVVHMMESVALPGGGGVKAAIKGYRIAIKTGT 496
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15597468 482 ARKASGRG-YADKsYRSLFVGMAPASDPQLVLAVMIDSPTRIGYFGGLVSAPTFSDIMAGSLRALAIPPDNL 552
Cdd:PRK15105 497 AKKVGPDGrYINK-YIAYTAGVAPASQPRFALVVVINDPQAGKYYGGAVSAPVFGAIMGGVLRTMNIEPDAL 567
|
|
| Transpeptidase |
pfam00905 |
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ... |
242-539 |
2.66e-100 |
|
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain] Cd Length: 296 Bit Score: 305.49 E-value: 2.66e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 242 GSAVLVNPKSGQILAMANFPSYNPNNRASFapafMRNRTLTDTFEPGSVIKPFSMSAALASGKFDENSQVSVAPGWM--- 318
Cdd:pfam00905 1 GSAVVLDPKTGEVLAMVGKPSYDPNGFIGP----LRNRAVTSRYEPGSTFKPFTALAALDNGVLKPDETIFDWPGKQqgg 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 319 -TIDGHTIHDVARRdvlTMTGVLINSSNIGMSKVALQIGPKPILEQLGRVGFGAPLSLGFPGENPGYLPfhEKWSNIATA 397
Cdd:pfam00905 77 kSIGDWNQDQVGIG---TLRQALEYSSNWYMQKLAQKLGADKLRSYLKKFGYGNKTGIGLPGENAGYLT--PYWLEGATA 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 398 SmsFGYSLAVNTAELAQAYSVFANDGKLVPLSLL-----RDNPQNQVRQAMDPQIARRIRAMLQTVVEDPKGVVRARVPG 472
Cdd:pfam00905 152 S--FGIGLTITPLQQAQAYAAIANGGKLVPPHLVksiedKVDPKVLNKLPISKSTAEKVKDMLRLVVNDGTGTGTAAVPG 229
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15597468 473 YHVAGKSGTARKA--SGRGYADKSYRSLFVGMAPASDPQLVLAVMIDSPTRigYFGGLVSAPTFSDIMA 539
Cdd:pfam00905 230 YKVAGKTGTAQVAgpKGGGYYDGAQIGWFVGYAPADNPKYAFAVLIDDPKR--YYGGKVAAPIFKDILE 296
|
|
| pbp2_mrdA |
TIGR03423 |
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ... |
9-538 |
1.51e-94 |
|
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 274573 [Multi-domain] Cd Length: 592 Bit Score: 300.59 E-value: 1.51e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 9 RFILVVTLFVLASLAV-SGRLVYLQVHDHEFLADQGDLRSIRDLPIPVTRGMITDRNGEPLAVSTEVASIWCNPREMaAH 87
Cdd:TIGR03423 1 RRALVLGGLVLALFGVlAARLFYLQVIRGEEYATLSEDNRIRLVPIPPPRGLILDRNGVLLADNRPSFSLEIVPEKV-DD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 88 LDEV-PRLAGALH-RPAAALLAQLQANPNKRF--LYLERGLSPIEAS--EVMALGITGVHQIKEYKRFYPSSELTAQLIG 161
Cdd:TIGR03423 80 LDATlDRLAKLLDlDPEDIARFLKELKRSRRFepIPLKSDLTEEEVArfAVNQYRLPGVEIEARLKRYYPYGELAAHVLG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 162 LVN-IDGR----------------GQEGTELGFNDWLSGKDGVREVAINPRGslvNSIKVLKT--PKASQDVALSIDLRL 222
Cdd:TIGR03423 160 YVGeINEEdlerlepanyaggdyiGKSGIEKYYEDELRGKPGYREVEVNARG---RVIRTLSRvpPVPGKDLVLTIDARL 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 223 QFIAYKAlekavlkFGAHSGSAVLVNPKSGQILAMANFPSYNPN---NRASFA-----------PafMRNRTLTDTFEPG 288
Cdd:TIGR03423 237 QQAAEKA-------LGGRRGAVVVMDPRTGEILAMVSTPSFDPNlfvDGISSKdykallndpdrP--LLNRAIQGVYPPG 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 289 SVIKPFSMSAALASGKFDENSQVSvAPGWMTIDGHTIHDVARRD--VLTMTGVLINSSNIGMSKVALQIGPKPILEQLGR 366
Cdd:TIGR03423 308 STFKPVVALAALEEGVITPETRIY-CPGYFQLGGRRFRCWKRGGhgRVDLRKAIEESCDVYFYQLALRLGIDKIAEYAKR 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 367 VGFGAPLSLGFPGENPGYLP--------FHEKWSNIATASMSFG--YSLAvnTA-ELAQAYSVFANDGKLVPLSLLRD-- 433
Cdd:TIGR03423 387 FGFGQKTGIDLPGEKSGLVPsrewkrkrFGQPWYPGDTLNVSIGqgYVLV--TPlQLAVATAALANGGKLYKPHLVKSie 464
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 434 NPQNQVRQAMDPQIARR----------IRAMLQTVVEDPKG-VVRARVP-GYHVAGKSGTA----RKASGRGYAD---KS 494
Cdd:TIGR03423 465 DPDGGVVRRTEPEVLRPlpispenldvVREGMRDVVNGPGGtARRARLGlPYKMAGKTGTAqvvsLKQGEKYDAEqipER 544
|
570 580 590 600
....*....|....*....|....*....|....*....|....*.
gi 15597468 495 YR--SLFVGMAPASDPQLVLAVMIDSptriGYFGGLVSAPTFSDIM 538
Cdd:TIGR03423 545 LRdhALFVAFAPYDNPKIAVAVIVEH----GGGGSSAAAPIARKIM 586
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| FtsI |
COG0768 |
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ... |
1-548 |
0e+00 |
|
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain] Cd Length: 568 Bit Score: 580.24 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 1 MSSQRR----NYRFILVVTLFVLASLAVSGRLVYLQVHDHEFLADQGDLRSIRDLPIPVTRGMITDRNGEPLAVSTEVAS 76
Cdd:COG0768 1 MKRKKEkrlfRRRLLLLFLLVLLLFLLLVGRLFYLQVVEGDEYAELAEENRIRTVPIPAPRGLIYDRNGNVLATNVPVYS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 77 IWCNPREMAAHLDEVPRLAGALHRPAAALLAQLqaNPNKRF-LYLERGLSPIEASEVMALGITGVHQIKEYKRFYPSSEL 155
Cdd:COG0768 81 LYADPEEVKDPEETAEKLAKLLGLDPEELRKKL--KKKSRFpVYLKRNLSPEEAARIRALKLPGVYVEAEYKRYYPYGEL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 156 TAQLIGLVNI----DGRGQEGTELGFNDWLSGKDGVREVAINPRGSLVNSIKVLKTPKASQDVALSIDLRLQFIAYKALE 231
Cdd:COG0768 159 AAHVLGYVGEinggDGIGKSGLEKAYEDLLRGTPGKRRVEVDARGRVIRDLGEEKPPVPGKDLVLTIDSDLQKIAEEALK 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 232 KAVLKFGAHSGSAVLVNPKSGQILAMANFPSYNPNNRASFAPAFMRNRTLTDTFEPGSVIKPFSMSAALASGKFDENSQV 311
Cdd:COG0768 239 KAVEEYKAKSGAVVVMDPKTGEILAMASYPSFDPNLFVGGPDEPLRNRAVQGTYEPGSTFKPFTAAAALEEGVITPDTTF 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 312 SVaPGWMTIDGHTIHDVARRD--VLTMTGVLINSSNIGMSKVALQIGPKPILEQLGRVGFGAPLSLGFPGENPGYLPFHE 389
Cdd:COG0768 319 DC-PGYYRVGGRTIRDWDRGGhgTLTLTEALAKSSNVGFYKLALRLGIDKLYDYLKKFGLGQKTGIDLPGEASGLLPSPK 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 390 KWSNIATASMSFGYSLAVNTAELAQAYSVFANDGKLVPLSLLRD--NPQNQV--------RQAMDPQIARRIRAMLQTVV 459
Cdd:COG0768 398 RWYPGETATMSIGQGLSVTPLQLAQAYAAIANGGVLVKPHLVKEivDPDGEVvkeepevlRRVISPETAETVREGMEGVV 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 460 EDPKGV-VRARVPGYHVAGKSGTARKAS--GRGYADKSYRSLFVGMAPASDPQLVLAVMIDSPTRiGYFGGLVSAPTFSD 536
Cdd:COG0768 478 NEPGGTaRRAAIPGYRVAGKTGTAQVVDigNGGYYKGRHIASFVGFAPADNPRYAVAVVVENPGG-GAYGGTVAAPVFRE 556
|
570
....*....|..
gi 15597468 537 IMAGSLRALAIP 548
Cdd:COG0768 557 IMEAYLRLLGPP 568
|
|
| PRK15105 |
PRK15105 |
peptidoglycan synthase FtsI; Provisional |
7-552 |
9.91e-149 |
|
peptidoglycan synthase FtsI; Provisional
Pssm-ID: 185060 [Multi-domain] Cd Length: 578 Bit Score: 440.03 E-value: 9.91e-149
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 7 NYRFILVVTLFVLASLAVSGRLVYLQVHDHEFLADQGDLRSIRDLPIPVTRGMITDRNGEPLAVSTEVASIWCNPREMAA 86
Cdd:PRK15105 20 SWRFALLCGCILLALVFLLGRVAWLQVINPDMLVREGDMRSLRVQEVSTSRGMITDRSGRPLAVSVPVKAIWADPKEVHD 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 87 H----LDEVPR-LAGALHRPAAALLAQLQANPNKRFLYLERGLSPIEASEVMALGITGVHQIKEYKRFYPSSELTAQLIG 161
Cdd:PRK15105 100 AggisVDDRWKaLADALNIPLDQLSARINANPKGRFIYLARQVNPDMADYIKKLKLPGIHLREESRRYYPSGEVTAHLIG 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 162 LVNIDGRGQEGTELGFNDWLSGKDGVREVAINPRGSLVNSIKVLKTpKASQDVALSIDLRLQFIAYKALEKAVLKFGAHS 241
Cdd:PRK15105 180 FTNVDSQGIEGVEKSFDKWLTGQPGERIVRKDRYGRVIEDISSTDS-QAAHNLALSIDERLQALVYRELNNAVAFNKAES 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 242 GSAVLVNPKSGQILAMANFPSYNPNNRASFAPAFMRNRTLTDTFEPGSVIKPFSMSAALASGKFDENSQVSVAPgwMTID 321
Cdd:PRK15105 259 GSAVLVDVNTGEVLAMANSPSYNPNNLSGTPKDAMRNRAITDVFEPGSTVKPMVVMTALQRGVVKENSVLNTVP--YRIN 336
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 322 GHTIHDVARRDVLTMTGVLINSSNIGMSKVALQIGPKPILEQLGRVGFGAPLSLGFPGENPGYLPFHEKWSNIATASMSF 401
Cdd:PRK15105 337 GHEIKDVARYSELTLTGVLQKSSNVGVSKLALAMPSSALVDTYSRFGLGKATNLGLVGERSGLYPQKQRWSDIERATFSF 416
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 402 GYSLAVNTAELAQAYSVFANDGKLVPLSLLRDNPQNQVRQAMDPQIARRIRAMLQTVVEDPKGVVRARVPGYHVAGKSGT 481
Cdd:PRK15105 417 GYGLMVTPLQLARVYATIGSYGIYRPLSITKVDPPVPGERVFPESIVRTVVHMMESVALPGGGGVKAAIKGYRIAIKTGT 496
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15597468 482 ARKASGRG-YADKsYRSLFVGMAPASDPQLVLAVMIDSPTRIGYFGGLVSAPTFSDIMAGSLRALAIPPDNL 552
Cdd:PRK15105 497 AKKVGPDGrYINK-YIAYTAGVAPASQPRFALVVVINDPQAGKYYGGAVSAPVFGAIMGGVLRTMNIEPDAL 567
|
|
| Transpeptidase |
pfam00905 |
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ... |
242-539 |
2.66e-100 |
|
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain] Cd Length: 296 Bit Score: 305.49 E-value: 2.66e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 242 GSAVLVNPKSGQILAMANFPSYNPNNRASFapafMRNRTLTDTFEPGSVIKPFSMSAALASGKFDENSQVSVAPGWM--- 318
Cdd:pfam00905 1 GSAVVLDPKTGEVLAMVGKPSYDPNGFIGP----LRNRAVTSRYEPGSTFKPFTALAALDNGVLKPDETIFDWPGKQqgg 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 319 -TIDGHTIHDVARRdvlTMTGVLINSSNIGMSKVALQIGPKPILEQLGRVGFGAPLSLGFPGENPGYLPfhEKWSNIATA 397
Cdd:pfam00905 77 kSIGDWNQDQVGIG---TLRQALEYSSNWYMQKLAQKLGADKLRSYLKKFGYGNKTGIGLPGENAGYLT--PYWLEGATA 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 398 SmsFGYSLAVNTAELAQAYSVFANDGKLVPLSLL-----RDNPQNQVRQAMDPQIARRIRAMLQTVVEDPKGVVRARVPG 472
Cdd:pfam00905 152 S--FGIGLTITPLQQAQAYAAIANGGKLVPPHLVksiedKVDPKVLNKLPISKSTAEKVKDMLRLVVNDGTGTGTAAVPG 229
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15597468 473 YHVAGKSGTARKA--SGRGYADKSYRSLFVGMAPASDPQLVLAVMIDSPTRigYFGGLVSAPTFSDIMA 539
Cdd:pfam00905 230 YKVAGKTGTAQVAgpKGGGYYDGAQIGWFVGYAPADNPKYAFAVLIDDPKR--YYGGKVAAPIFKDILE 296
|
|
| pbp2_mrdA |
TIGR03423 |
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ... |
9-538 |
1.51e-94 |
|
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 274573 [Multi-domain] Cd Length: 592 Bit Score: 300.59 E-value: 1.51e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 9 RFILVVTLFVLASLAV-SGRLVYLQVHDHEFLADQGDLRSIRDLPIPVTRGMITDRNGEPLAVSTEVASIWCNPREMaAH 87
Cdd:TIGR03423 1 RRALVLGGLVLALFGVlAARLFYLQVIRGEEYATLSEDNRIRLVPIPPPRGLILDRNGVLLADNRPSFSLEIVPEKV-DD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 88 LDEV-PRLAGALH-RPAAALLAQLQANPNKRF--LYLERGLSPIEAS--EVMALGITGVHQIKEYKRFYPSSELTAQLIG 161
Cdd:TIGR03423 80 LDATlDRLAKLLDlDPEDIARFLKELKRSRRFepIPLKSDLTEEEVArfAVNQYRLPGVEIEARLKRYYPYGELAAHVLG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 162 LVN-IDGR----------------GQEGTELGFNDWLSGKDGVREVAINPRGslvNSIKVLKT--PKASQDVALSIDLRL 222
Cdd:TIGR03423 160 YVGeINEEdlerlepanyaggdyiGKSGIEKYYEDELRGKPGYREVEVNARG---RVIRTLSRvpPVPGKDLVLTIDARL 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 223 QFIAYKAlekavlkFGAHSGSAVLVNPKSGQILAMANFPSYNPN---NRASFA-----------PafMRNRTLTDTFEPG 288
Cdd:TIGR03423 237 QQAAEKA-------LGGRRGAVVVMDPRTGEILAMVSTPSFDPNlfvDGISSKdykallndpdrP--LLNRAIQGVYPPG 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 289 SVIKPFSMSAALASGKFDENSQVSvAPGWMTIDGHTIHDVARRD--VLTMTGVLINSSNIGMSKVALQIGPKPILEQLGR 366
Cdd:TIGR03423 308 STFKPVVALAALEEGVITPETRIY-CPGYFQLGGRRFRCWKRGGhgRVDLRKAIEESCDVYFYQLALRLGIDKIAEYAKR 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 367 VGFGAPLSLGFPGENPGYLP--------FHEKWSNIATASMSFG--YSLAvnTA-ELAQAYSVFANDGKLVPLSLLRD-- 433
Cdd:TIGR03423 387 FGFGQKTGIDLPGEKSGLVPsrewkrkrFGQPWYPGDTLNVSIGqgYVLV--TPlQLAVATAALANGGKLYKPHLVKSie 464
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 434 NPQNQVRQAMDPQIARR----------IRAMLQTVVEDPKG-VVRARVP-GYHVAGKSGTA----RKASGRGYAD---KS 494
Cdd:TIGR03423 465 DPDGGVVRRTEPEVLRPlpispenldvVREGMRDVVNGPGGtARRARLGlPYKMAGKTGTAqvvsLKQGEKYDAEqipER 544
|
570 580 590 600
....*....|....*....|....*....|....*....|....*.
gi 15597468 495 YR--SLFVGMAPASDPQLVLAVMIDSptriGYFGGLVSAPTFSDIM 538
Cdd:TIGR03423 545 LRdhALFVAFAPYDNPKIAVAVIVEH----GGGGSSAAAPIARKIM 586
|
|
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
217-554 |
1.45e-40 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 155.85 E-value: 1.45e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 217 SIDLRLQFIAYKALEKAV--LKFGAHSGSAVLVNPKSGQILAMANFPSYNPNNRasfapafmrNRTLTDTFEPGSVIKPF 294
Cdd:COG0744 300 TLDPKLQKAAEKAVKNVLpeGKPGGLQAALVVVDPKTGEVLAMVGGRDYGKSQF---------NRATQAKRQPGSTFKPF 370
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 295 SMSAALASGkFDENSQVSVAPGWMTIDGHTIHDVARRDV--LTMTGVLINSSNIGMSKVALQIGPKPILEQLGRvgfgap 372
Cdd:COG0744 371 VYAAALEQG-YTPATTVDDEPVTFPGGGWSPKNYDGRYRgpVTLREALANSLNTPAVRLAQEVGLDKVVDTARR------ 443
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 373 lsLGFPGENPGYLpfhekwsniataSMSFGySLAVNTAELAQAYSVFANDGKLVPLSLLR----------DNPQNQVRQA 442
Cdd:COG0744 444 --LGITSPLDPNP------------SLALG-TSEVSPLEMASAYATFANGGVYVEPHAITkvtdadgkvlYEAKPKCEQV 508
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 443 MDPQIARRIRAMLQTVVEDPKGvVRARVPGYHVAGKSGTArkasgRGYADksyrSLFVGMapasDPQLVLAVMI--DSPT 520
Cdd:COG0744 509 ISPEVAYLMTDMLQDVVTSGTG-RAARLPGRPVAGKTGTT-----NDNRD----AWFVGY----TPQLVTAVWVgnDDNS 574
|
330 340 350
....*....|....*....|....*....|....*....
gi 15597468 521 RIGY-FGGLVSAPTFSDIMAGSLRALAI----PPDNLQD 554
Cdd:COG0744 575 PMGYvTGGSLPAPIWRDFMEAALEGLPVedfpKPSGVVR 613
|
|
| PRK10795 |
PRK10795 |
penicillin-binding protein 2; Provisional |
1-538 |
1.63e-30 |
|
penicillin-binding protein 2; Provisional
Pssm-ID: 236761 [Multi-domain] Cd Length: 634 Bit Score: 126.04 E-value: 1.63e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 1 MSSQRRNYR--------FILVVTLFVLASLAVSGRLV----YLQVHDHEFLADQGDLRSIRDLPIPVTRGMITDRNGEPL 68
Cdd:PRK10795 1 MKKLQNSFRdytaesalFVRRALVAFLGILLLTGVLIanlyNLQIVRFTDYQTRSNENRIKLVPIAPSRGIIYDRNGTPL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 69 AVSTEVASIWCNPREmaahLDEVPRLAGALhRPAAALLAQLQANPNK------RF--LYLERGLSPIEASE--VMALGIT 138
Cdd:PRK10795 81 ALNRTIYQLEMMPEK----VDNLQQTLDAL-RSVVDLTDDDIAAFRKerarsrRFtsIPVKTNLTEVQVARfaVNQYRFP 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 139 GVhQIKEYK-RFYPSSELTAQLIGLVN-IDGR--------------------GQEGTELGFNDWLSGKDGVREVAINPRG 196
Cdd:PRK10795 156 GV-EVKGYQrRYYPYGSALTHVIGYVSkINDKdverldkegklanyaathdiGKLGIERYYEDVLHGKTGYEEVEVNNRG 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 197 SLVNSIKVlKTPKASQDVALSIDLRLQFIAYKALekavlkfgAHSGSAVLV-NPKSGQILAMANFPSYNPN--------- 266
Cdd:PRK10795 235 RVIRQLHE-QPPQAGHDIYLTLDLKLQQYIETLL--------AGSRAAVVVtDPRTGGILALVSTPSYDPNlfvdgissk 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 267 ---------NRAsfapafMRNRTLTDTFEPGSVIKPFSMSAALASGKFDENSQVsVAPGWMTIDGhtiHDVARRD----- 332
Cdd:PRK10795 306 dysgllndpNRP------LINRATQGVYPPASTVKPYVAVSALSAGVITRNTSL-FDPGWWQLPG---SEKRYRDwkkwg 375
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 333 --VLTMTGVLINSSNIGMSKVALQIGPKPILEQLGRVGFGAPLSLGFPGENPGYLP--------FHEKWSNIATASMSFG 402
Cdd:PRK10795 376 hgRLNVTKSLEESADTFFYQVAYDMGIDRLSEWMGKFGYGHYTGIDLAEERSGNMPtrewkqkrFKKPWYQGDTIPVGIG 455
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 403 YSLAVNTA-ELAQAYSVFANDGKLVPLSLLRDNPQNQV----RQAMDPQIArRIRAMLQTVVED--------PKGVVR-- 467
Cdd:PRK10795 456 QGYWTATPiQMSKALMTLINDGIVKVPHLLMSTAEDGKqvpwVQPHEPPVG-DIHSGYWEIAKDgmygvanrPNGTAHky 534
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 468 -ARVPgYHVAGKSGTARKASGRgyADKSYRS-----------LFVGMAPASDPQLVLAVMIDSptrigyfGGlvSAPTFS 535
Cdd:PRK10795 535 fASAP-YKIAAKSGTAQVFGLK--ANETYNAhkiaerlrdhkLMTAFAPYNNPQVAVAIILEN-------GG--AGPAVG 602
|
...
gi 15597468 536 DIM 538
Cdd:PRK10795 603 TIM 605
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
213-539 |
6.90e-30 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 123.52 E-value: 6.90e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 213 DVALSIDLRLQFIAYKALEKAVLKFGAHSG-----SAVLVNPKSGQILAMANFPSYNPN--NRASFApafMRnrtltdtf 285
Cdd:TIGR02074 223 KIYTTLDLDAQKAAEKVLNTGLRVAGRRDGddlqaALVAIDPDTGAVRALVGGRDYGKSqfNRATQA---KR-------- 291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 286 EPGSVIKPFSMSAALASGkFDENSQVSVAP-GWMTIDGHTIHDVAR--RDVLTMTGVLINSSNIGMSKVALQIGPKPILE 362
Cdd:TIGR02074 292 QPGSTFKPFVYAAALEKG-LTPATIVNDEPiTYNGNGPWSPKNYGGgyRGNVTLRQALAQSRNIPAVRLLQEVGLDKVVA 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 363 QLGRVGFGAPLslgfpgeNPGYlpfhekwsniataSMSFGySLAVNTAELAQAYSVFANDGKLVPLSLLRD--------- 433
Cdd:TIGR02074 371 LAKRFGITSPL-------DPVL-------------SLALG-TVEVSPLEMASAYAVFANGGKYVEPHGIRKivdrdgkvi 429
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 434 -NPQNQVRQAMDPQIARRIRAMLQTVVEDPKGvVRARVPGYHVAGKSGTarkasgrgyADKSYRSLFVGMApasdPQLVL 512
Cdd:TIGR02074 430 yENKPKTTQVISPATAYIMTDMLKGVVESGTG-RSARLPGRPVAGKTGT---------TQNWRDAWFVGYT----PYYVT 495
|
330 340 350
....*....|....*....|....*....|..
gi 15597468 513 AVMI-----DSPTRIGYfGGLVSAPTFSDIMA 539
Cdd:TIGR02074 496 AVWVgyddkKTLGKSGT-GGGLAAPIWRDFMA 526
|
|
| MrcA |
COG5009 |
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis]; |
241-543 |
3.43e-20 |
|
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 444033 [Multi-domain] Cd Length: 785 Bit Score: 94.84 E-value: 3.43e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 241 SGSAVLVNPKSGQILAMANFPSYNPN--NRASFApafMRnrtltdtfEPGSVIKPFSMSAALASGkFDENSQVSVAPgwm 318
Cdd:COG5009 422 QGALVALDPHTGAVLALVGGFDFEQSkfNRATQA---KR--------QPGSSFKPFVYAAALDNG-YTPATIINDAP--- 486
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 319 tidgHTIHDVARRDV-------------LTMTGVLINSSNIGMSKVALQIGPKPILEQLGRVGFGAPLslgfpgenPGYL 385
Cdd:COG5009 487 ----IVFDDGGGGGVwrpknysgkfygpTTLREALEKSRNLVTVRLLQDVGIDYVIDYAERFGIYSKL--------PPNL 554
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 386 pfhekwsniataSMSFGySLAVNTAELAQAYSVFANDGKLV--------------------PLSLLRDNPQNQV------ 439
Cdd:COG5009 555 ------------SLALG-SGEVTPLEMARAYAVFANGGYRVepylidriedrngkviyradPARACEDCDAAEWdgaepr 621
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 440 -----RQAMDPQIARRIRAMLQTVVEDPKGvVRARVPGYHVAGKSGT---ARKASgrgyadksyrslFVGMApasdPQLV 511
Cdd:COG5009 622 lpdpaEQVIDPRTAYQMTSMLRGVVQRGTG-RRARALGRDIAGKTGTtndSKDAW------------FVGFT----PDLV 684
|
330 340 350
....*....|....*....|....*....|....*.
gi 15597468 512 LAVMI--DSPTRIGY--FGGLVSAPTFSDIMAGSLR 543
Cdd:COG5009 685 AGVWVgfDDPRSLGRgeTGGRAALPIWIDFMKAALK 720
|
|
| PBP_dimer |
pfam03717 |
Penicillin-binding Protein dimerization domain; This domain is found at the N terminus of ... |
52-196 |
1.19e-15 |
|
Penicillin-binding Protein dimerization domain; This domain is found at the N terminus of Class B High Molecular Weight Penicillin-Binding Proteins. Its function has not been precisely defined, but is strongly implicated in PBP polymerization. The domain forms a largely disordered 'sugar tongs' structure.
Pssm-ID: 427460 [Multi-domain] Cd Length: 178 Bit Score: 75.05 E-value: 1.19e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 52 PIPVTRGMITDRNGEPLAVSTEVASIWCNPREM--AAHLDEVPRLAGALHRPAAA-------LLAQLQANPNKRFLYLER 122
Cdd:pfam03717 1 PIPAPRGEIYDRNGVVLATNKPVYSLTITPSKLkkADALKTALKLAKLLSNYEDLddedlteRFLKMNSYKSYYPVVIKK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 123 GLSPIEASEV--MALGITGVHQIKEYKRFYPSSELTAQLIGLVN-IDGR----------------GQEGTELGFNDWLSG 183
Cdd:pfam03717 81 NLSEEEVARIeeNLLELPGVSIETDPVRYYPYGELAAHLLGYVGeITEEelekyldkgysrgdlvGKSGLEKQYESVLRG 160
|
170
....*....|...
gi 15597468 184 KDGVREVAINPRG 196
Cdd:pfam03717 161 KDGVRQVEVDALG 173
|
|
| PbpC |
COG4953 |
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope ... |
214-553 |
4.04e-11 |
|
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443980 [Multi-domain] Cd Length: 773 Bit Score: 66.01 E-value: 4.04e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 214 VALSIDLRLQfiayKALEKAVLKF-------GAHSGSAVLVNPKSGQILAMANFPSYNPNNRASFAPAFMRNRTltdtfe 286
Cdd:COG4953 274 IRTTLDAGLQ----RRLERLVRRYvrrlkqnGIHNAAVLVVDNRTGEVLAYVGSADFFDASRQGQVDMVRALRS------ 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 287 PGSVIKPFSMSAALASGKfdensqvsVAPgwMTIdghtIHDVARR---------------DVlTMTGVLINSSNIGMSKV 351
Cdd:COG4953 344 PGSTLKPFLYGLALDQGL--------IHP--ETL----LADVPTSfggyrpenfdgtfqgPV-SAREALARSLNIPAVRL 408
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 352 ALQIGPKPILEQLGRVGFGAPLSlgfPGENPGylpfhekwsniatASMSFGySLAVNTAELAQAYSVFANDGKLVPLSLL 431
Cdd:COG4953 409 LEALGPARFYARLRRAGLRLLLP---PAEHYG-------------LSLILG-GAEVTLEELVGLYAALARGGEARPLRLL 471
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 432 RDNPQNQVRQAMDPQIARRIRAMLQTVVE-DPKGVVRARVPGYHVAGKSGTArkasgRGYADksyrslfvGMAPASDPQL 510
Cdd:COG4953 472 AGEPASPGRRLLSPGAAWLVRDILSDVPRpDGAFGWRALDSPPPIAWKTGTS-----YGFRD--------AWAVGFTGRY 538
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 15597468 511 VLAVMI---DSPTRIGYFGGLVSAPTFSDIMA---GSLRALAIP-PDNLQ 553
Cdd:COG4953 539 TVGVWVgnpDGTPVPGLTGAEAAAPLLFDIFDllpASRWPLPFPpPAGLL 588
|
|
| PBP_1c |
TIGR02073 |
penicillin-binding protein 1C; This subfamily of the penicillin binding proteins includes the ... |
207-539 |
4.12e-07 |
|
penicillin-binding protein 1C; This subfamily of the penicillin binding proteins includes the member from E. coli designated penicillin-binding protein 1C. Members have both transglycosylase and transpeptidase domains and are involved in forming cross-links in the late stages of peptidoglycan biosynthesis. All members of this subfamily are presumed to have the same basic function. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273954 [Multi-domain] Cd Length: 727 Bit Score: 52.81 E-value: 4.12e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 207 TPKASQDVALSIDLRLQFIAYKALE---KAVLKFGAHSGSAVLVNPKSGQILAMANfpSYNPNNRASFAPAFMRN--RTl 281
Cdd:TIGR02073 237 RPEIASVIVSTLDADLQRRLEELARrylSALRPRGISNLAILVVDNRSGAVLAYVG--SADFFDDSNSGQVDGVRapRS- 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 282 tdtfePGSVIKPFSMSAALASGKFDENSQVSVAPgwMTIDGHTIHDVARR--DVLTMTGVLINSSNIGMSKVALQIGPKP 359
Cdd:TIGR02073 314 -----PGSTLKPFLYALALDDGLLHPDSLLKDVP--LRFGDYAPENFDKTfhGPVPAREALARSLNIPAVRLLERVGPPR 386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 360 ILEQLGRVGFgaplslgfpgenpgylpfhekwSNIATASMSFGYSLAVNTAE-----LAQAYSVFANDGKLVPL-SLLRD 433
Cdd:TIGR02073 387 FADFLRQAGL----------------------NLLKPKSDYYGLSLALGGAEitlqdLANLYAMLANQGLSGPLrFLQTD 444
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 434 NPQNQVRQAMDPQIARRIRAML----QTVVEDPKGVVRARVPgyhVAGKSGTA---RKASGRGYadksyrslfvgmapas 506
Cdd:TIGR02073 445 AKRPERERLLSPGAAWIVLDILkdrpRPDDTLPLSALPTRLP---LAWKTGTSygfRDAWAAGV---------------- 505
|
330 340 350
....*....|....*....|....*....|....*.
gi 15597468 507 DPQLVLAVMIDSPT---RIGYFGGLVSAPTFSDIMA 539
Cdd:TIGR02073 506 SGRYTIGVWVGNFDgkpNPGFFGAAAAAPLLFDILD 541
|
|
| mrcB |
PRK09506 |
bifunctional glycosyl transferase/transpeptidase; Reviewed |
225-481 |
3.00e-05 |
|
bifunctional glycosyl transferase/transpeptidase; Reviewed
Pssm-ID: 236544 [Multi-domain] Cd Length: 830 Bit Score: 47.07 E-value: 3.00e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 225 IAYKALEKAV------LKFGAH----SGSAVLVNPKSGQILAM--ANFPSYNPNNRAsfapafMRNRTLTdtfepGSVIK 292
Cdd:PRK09506 443 VSQDAAEKAVeegipaLKKQRKlsdlETAMVVVDRFSGEVRAMvgGSEPQFAGYNRA------MQARRSI-----GSLAK 511
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 293 PFSMSAALAS-GKFDENSQVSVAPGWMTIDGHTI-----HDVARRDVLTMTGVLINSSNIGMSKVALQIGPKPILEQLGR 366
Cdd:PRK09506 512 PATYLTALSQpDKYRLNTWIADAPISLRQPNGQVwspqnDDRRFSGRVMLVDALTRSMNVPTVNLGMALGLPAVTDTWIK 591
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 367 vgfgaplsLGFPGENPGYLPfhekwsniataSMSFGySLAVNTAELAQAYSVFANDGKLVPLSLLR-----DNP---QN- 437
Cdd:PRK09506 592 --------LGVPKDQLNPVP-----------AMLLG-ALNLTPIEVAQAFQTIASGGNRAPLSALRsviaeDGKvlyQSf 651
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 15597468 438 -QVRQAMDPQIAR-RIRAMLQTVVEDPKGVVRARVPGYHVAGKSGT 481
Cdd:PRK09506 652 pQAERAVPAQAAYlTLYTMQQVVQRGTGRQLGAKYPNLHLAGKTGT 697
|
|
| PRK14850 |
PRK14850 |
penicillin-binding protein 1b; Provisional |
222-481 |
7.81e-03 |
|
penicillin-binding protein 1b; Provisional
Pssm-ID: 237835 [Multi-domain] Cd Length: 764 Bit Score: 39.06 E-value: 7.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 222 LQFIAYKALEKAV--------LKFGAH--SGSAVLVNPKSGQILAM--ANFPSYNPNNRASFApafmrNRTLtdtfepGS 289
Cdd:PRK14850 386 LDYISQNAAEQAVkigipilkRKKRLKdlEVAMVIIDRFSGEVRALigSSKPEFNGYNRALKA-----RRSI------GS 454
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 290 VIKPFSMSAALAS-GKFDENSQVSVAPGWMTIDGHTI-----HDVARRDVLTMTGVLINSSNIGMSKVALQIGPKPILEQ 363
Cdd:PRK14850 455 LSKPITYLTALSQpEKYHLNTWISDTPISIKLDNGQYwtpknNNFSFSGKVMLIDALIHSINIPTVHLSINLGLKKLVDS 534
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597468 364 LGRVGFGAPLSLGFPgenpgylpfhekwsniataSMSFGySLAVNTAELAQAYSVFANDGKLVPLSLLRD--NPQN---- 437
Cdd:PRK14850 535 WILLGISSNYITPLP-------------------SISLG-AINLTPMEVAQVFQIIGSGGYKSSLSSIRSiiSDDNkvly 594
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 15597468 438 ----QVRQAMDPQIARRIRAMLQTVVEdpKGVVRA---RVPGYHVAGKSGT 481
Cdd:PRK14850 595 qnfpQSKHVESSQASYLTLYAMQQVVK--SGTAKSlgtIFKEFSLAGKTGT 643
|
|
| |
