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Conserved domains on  [gi|15597547|ref|NP_251041|]
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ABC transporter permease [Pseudomonas aeruginosa PAO1]

Protein Classification

methionine ABC transporter permease( domain architecture ID 10005172)

methionine ABC transporter permease is the transmembrane (TM) subunit of the ABC transporter complex, such as MetNPQ, that is involved in methionine import, and is responsible for the translocation of the substrate across the membrane

EC:  7.4.2.11
Gene Ontology:  GO:0033232|GO:0048473|GO:0042626
PubMed:  22095702|11421270|25750732|24638992
TCDB:  3.A.1.24

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MetP COG2011
ABC-type methionine transport system, permease component [Amino acid transport and metabolism]; ...
 1-216 8.95e-98

ABC-type methionine transport system, permease component [Amino acid transport and metabolism];


:

Pssm-ID: 441614  Cd Length: 220  Bit Score: 283.10  E-value: 8.95e-98
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547   1 MSPMLERLWQGFLDTLLMIGASSAIVLLVGIPLALVLVTTGPGGIFEARLLNRILGGLVNVLRSVPFLILMVALIPFTRM 80
Cdd:COG2011   5 WSELWPLLLQATGETLYMVGVSTLIAVLLGLPLGVLLVLTRPGGLLPNPVLYRVLGVIVNIFRSIPFIILLVALIPLTRL 84

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547  81 IVGTSYGVWAAVVPLTIAATPFFARIAEVSLREVDHGLVEAAQAMGCERRHIICNVLLPEARPGIVGGFTITLVTMINSS 160
Cdd:COG2011  85 IVGTSIGTTAAIVPLTIAAIPFFARLVENALREVDPGVIEAAQAMGASPWQIIFKVLLPEALPSLILGLTVTLISLIGYS 164

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 15597547 161 AMAGAIGAGGLGDLAYRYGYQRFDTQVMLTVIIVLVLLVTLIQFGGDRLARLLNKR 216
Cdd:COG2011 165 AMAGAVGGGGLGDLAIRYGYQRFDTDVMLVTVVILIVLVQIIQFLGDRLARRLDHR 220
 
Name Accession Description Interval E-value
MetP COG2011
ABC-type methionine transport system, permease component [Amino acid transport and metabolism]; ...
 1-216 8.95e-98

ABC-type methionine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 441614  Cd Length: 220  Bit Score: 283.10  E-value: 8.95e-98
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547   1 MSPMLERLWQGFLDTLLMIGASSAIVLLVGIPLALVLVTTGPGGIFEARLLNRILGGLVNVLRSVPFLILMVALIPFTRM 80
Cdd:COG2011   5 WSELWPLLLQATGETLYMVGVSTLIAVLLGLPLGVLLVLTRPGGLLPNPVLYRVLGVIVNIFRSIPFIILLVALIPLTRL 84

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547  81 IVGTSYGVWAAVVPLTIAATPFFARIAEVSLREVDHGLVEAAQAMGCERRHIICNVLLPEARPGIVGGFTITLVTMINSS 160
Cdd:COG2011  85 IVGTSIGTTAAIVPLTIAAIPFFARLVENALREVDPGVIEAAQAMGASPWQIIFKVLLPEALPSLILGLTVTLISLIGYS 164

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 15597547 161 AMAGAIGAGGLGDLAYRYGYQRFDTQVMLTVIIVLVLLVTLIQFGGDRLARLLNKR 216
Cdd:COG2011 165 AMAGAVGGGGLGDLAIRYGYQRFDTDVMLVTVVILIVLVQIIQFLGDRLARRLDHR 220
PRK10782 PRK10782
D-methionine ABC transporter permease MetI;
4-216 3.92e-56

D-methionine ABC transporter permease MetI;


Pssm-ID: 182726  Cd Length: 217  Bit Score: 177.62  E-value: 3.92e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547    4 MLERLWQGFLDTLLMIGASSAIVLLVGIPLALVLVTTGPGGIFEARLLNRILGGLVNVLRSVPFLILMVALIPFTRMIVG 83
Cdd:PRK10782   5 MMWLLVRGVWETLAMTFVSGFFGFVIGLPVGVLLYVTRPGQIIANAKLYRTLSALVNIFRSIPFIILLVWMIPFTRVIVG 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547   84 TSYGVWAAVVPLTIAATPFFARIAEVSLREVDHGLVEAAQAMGCERRHIICNVLLPEARPGIVGGFTITLVTMINSSAMA 163
Cdd:PRK10782  85 TSIGLQAAIVPLTVGAAPFIARMVENALLEIPTGLIEASRAMGATPMQIVRKVLLPEALPGLVNAATITLITLVGYSAMG 164

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 15597547  164 GAIGAGGLGDLAYRYGYQRFDTQVMLTVIIVLVLLVTLIQFGGDRLARLLNKR 216
Cdd:PRK10782 165 GAVGAGGLGQIGYQYGYIGYNATVMNTVLVLLVILVYLIQFAGDRIVRAVTHK 217
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 49-217 1.63e-11

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 60.78  E-value: 1.63e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547    49 RLLNRILGGLVNVLRSVPFLILMVALIPFTRMIVgTSYGVWAAVVPLTIAATPFFARIAEVSLREVDHGLVEAAQAMGCE 128
Cdd:pfam00528  14 RRLDRLLRPLIDLLQALPSFVLAILLVVIAILSI-LGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGAS 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547   129 RRHIICNVLLPEARPGIVGGFTITLVTMINSSAMAGAIGAGGLGDLAYRYGYQRFDTQVMLTVIIVLVLLVTLIQFGGDR 208
Cdd:pfam00528  93 RWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAILGYDYPEIQGPVLAAALILLLLNLLVDI 172


                  ....*....
gi 15597547   209 LARLLNKRL 217
Cdd:pfam00528 173 LQRLLDPRV 181
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 12-202 2.19e-11

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 60.37  E-value: 2.19e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547  12 FLDTLLMIGASSAIVLLVGIPLALVLVttgpggiFEARLLNRILGGLVNVLRSVPFLILMVALIPFTRMIVGTS---YGV 88
Cdd:cd06261   1 LLNTLLLALIATLLALVLGLLLGIILA-------RKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGilpGLG 73

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547  89 WAAVVPLTIAATPFFARIAEVSLREVDHGLVEAAQAMGCERRHIICNVLLPEARPGIVGGFTITLVTMINSSAMAGAIGA 168
Cdd:cd06261  74 LPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGG 153

                       170       180       190
                ....*....|....*....|....*....|....
gi 15597547 169 GGLGDLAYRYGYQRFDTQVMLTVIIVLVLLVTLI 202
Cdd:cd06261 154 GEAPGPGTGLLLIFAILFPGDLGVAAAVALILLL 187
PhnE TIGR01097
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound ...
 5-147 1.81e-08

phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions]


Pssm-ID: 273441 [Multi-domain]  Cd Length: 250  Bit Score: 52.93  E-value: 1.81e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547     5 LERLWQGFLDTLLMIGASSAIVLLVGIPLALVlvttGPGGIFEARLLNRILGGLVNVLRSVPFLILmvALIpftrMIVGT 84
Cdd:TIGR01097  53 LPRILKALLETLAMAILGTVLAAVLAVPLALL----AARNITPSPWLYGLARLLLNFLRAIPELVW--ALI----FVAAV 122

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15597547    85 SYGVWAAVVPLTIAATPFFARIAEVSLREVDHGLVEAAQAMGCERRHIICNVLLPEARPGIVG 147
Cdd:TIGR01097 123 GLGPFAGVLALAFHTVGFLGKLFAEAIEEVDPGPVEALRATGASKLQVIRYGVLPQVLPQFLS 185
 
Name Accession Description Interval E-value
MetP COG2011
ABC-type methionine transport system, permease component [Amino acid transport and metabolism]; ...
 1-216 8.95e-98

ABC-type methionine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 441614  Cd Length: 220  Bit Score: 283.10  E-value: 8.95e-98
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547   1 MSPMLERLWQGFLDTLLMIGASSAIVLLVGIPLALVLVTTGPGGIFEARLLNRILGGLVNVLRSVPFLILMVALIPFTRM 80
Cdd:COG2011   5 WSELWPLLLQATGETLYMVGVSTLIAVLLGLPLGVLLVLTRPGGLLPNPVLYRVLGVIVNIFRSIPFIILLVALIPLTRL 84

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547  81 IVGTSYGVWAAVVPLTIAATPFFARIAEVSLREVDHGLVEAAQAMGCERRHIICNVLLPEARPGIVGGFTITLVTMINSS 160
Cdd:COG2011  85 IVGTSIGTTAAIVPLTIAAIPFFARLVENALREVDPGVIEAAQAMGASPWQIIFKVLLPEALPSLILGLTVTLISLIGYS 164

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 15597547 161 AMAGAIGAGGLGDLAYRYGYQRFDTQVMLTVIIVLVLLVTLIQFGGDRLARLLNKR 216
Cdd:COG2011 165 AMAGAVGGGGLGDLAIRYGYQRFDTDVMLVTVVILIVLVQIIQFLGDRLARRLDHR 220
PRK10782 PRK10782
D-methionine ABC transporter permease MetI;
4-216 3.92e-56

D-methionine ABC transporter permease MetI;


Pssm-ID: 182726  Cd Length: 217  Bit Score: 177.62  E-value: 3.92e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547    4 MLERLWQGFLDTLLMIGASSAIVLLVGIPLALVLVTTGPGGIFEARLLNRILGGLVNVLRSVPFLILMVALIPFTRMIVG 83
Cdd:PRK10782   5 MMWLLVRGVWETLAMTFVSGFFGFVIGLPVGVLLYVTRPGQIIANAKLYRTLSALVNIFRSIPFIILLVWMIPFTRVIVG 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547   84 TSYGVWAAVVPLTIAATPFFARIAEVSLREVDHGLVEAAQAMGCERRHIICNVLLPEARPGIVGGFTITLVTMINSSAMA 163
Cdd:PRK10782  85 TSIGLQAAIVPLTVGAAPFIARMVENALLEIPTGLIEASRAMGATPMQIVRKVLLPEALPGLVNAATITLITLVGYSAMG 164

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 15597547  164 GAIGAGGLGDLAYRYGYQRFDTQVMLTVIIVLVLLVTLIQFGGDRLARLLNKR 216
Cdd:PRK10782 165 GAVGAGGLGQIGYQYGYIGYNATVMNTVLVLLVILVYLIQFAGDRIVRAVTHK 217
OpuBB COG1174
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
 5-216 4.19e-12

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440787 [Multi-domain]  Cd Length: 212  Bit Score: 62.76  E-value: 4.19e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547   5 LERLWQGFLDTLLMIGASSAIVLLVGIPLALVLVTTGPGGifearllnRILGGLVNVLRSVPFLILMVALIPFTrmivgt 84
Cdd:COG1174  13 RDGILALLLEHLLLVLLALLIALLIAVPLGILITRRRRLA--------GLVLGVANILQTIPSLALLALLIPLL------ 78

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547  85 SYGVWAAVVPLTIAATPFFARIAEVSLREVDHGLVEAAQAMGCERRHIICNVLLPEARPGIVGGFTITLVTMINSSAMAG 164
Cdd:COG1174  79 GIGPAPAIIALVLYALLPILRNTYTGLRSVDPAVVEAARGMGMTPWQRLWRVELPLALPVILAGIRTAAVQNIGTATLAA 158

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|..
gi 15597547 165 AIGAGGLGDLAYRyGYQRFDTQVMLTVIIVLVLLVTLIQFGGDRLARLLNKR 216
Cdd:COG1174 159 LIGAGGLGDLIFD-GLQLNNTALILAGAILVALLALLVDLLLALLERLLTPR 209
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 49-217 1.63e-11

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 60.78  E-value: 1.63e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547    49 RLLNRILGGLVNVLRSVPFLILMVALIPFTRMIVgTSYGVWAAVVPLTIAATPFFARIAEVSLREVDHGLVEAAQAMGCE 128
Cdd:pfam00528  14 RRLDRLLRPLIDLLQALPSFVLAILLVVIAILSI-LGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGAS 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547   129 RRHIICNVLLPEARPGIVGGFTITLVTMINSSAMAGAIGAGGLGDLAYRYGYQRFDTQVMLTVIIVLVLLVTLIQFGGDR 208
Cdd:pfam00528  93 RWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAILGYDYPEIQGPVLAAALILLLLNLLVDI 172


                  ....*....
gi 15597547   209 LARLLNKRL 217
Cdd:pfam00528 173 LQRLLDPRV 181
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
 8-217 1.75e-11

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 61.70  E-value: 1.75e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547   8 LWQGFLDTLLMIGASSAIVLLVGIPLALVLVTTgpggifeaRLLNRILGGLVNVLRSVPflilMVALIPFTRMIVGtsYG 87
Cdd:COG0600  59 LWEHLLASLLRVLLGFALAALLGVPLGLLLGLS--------RLLRRLLDPLLVFLRPIP----PLALAPLLILWFG--IG 124

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547  88 VWAAVVPLTIAATPFFARIAEVSLREVDHGLVEAAQAMGCERRHIICNVLLPEARPGIVGGFTITLVT---------MIN 158
Cdd:COG0600 125 EASKIFVIFLGAFFPILLNTAAGVRSVDPELLELARSLGASRWQILRKVVLPAALPYIFTGLRIALGLawiglvvaeLLG 204

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15597547 159 SSAMagaigagglgdLAYR--YGYQRFDTQVMLTVIIVLVLLVTLIqfggDRLARLLNKRL 217
Cdd:COG0600 205 ASSG-----------LGYLilDARQLLDTDLVFAAILVIGLLGLLL----DLLLRLLERRL 250
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 12-202 2.19e-11

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 60.37  E-value: 2.19e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547  12 FLDTLLMIGASSAIVLLVGIPLALVLVttgpggiFEARLLNRILGGLVNVLRSVPFLILMVALIPFTRMIVGTS---YGV 88
Cdd:cd06261   1 LLNTLLLALIATLLALVLGLLLGIILA-------RKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGilpGLG 73

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547  89 WAAVVPLTIAATPFFARIAEVSLREVDHGLVEAAQAMGCERRHIICNVLLPEARPGIVGGFTITLVTMINSSAMAGAIGA 168
Cdd:cd06261  74 LPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGG 153

                       170       180       190
                ....*....|....*....|....*....|....
gi 15597547 169 GGLGDLAYRYGYQRFDTQVMLTVIIVLVLLVTLI 202
Cdd:cd06261 154 GEAPGPGTGLLLIFAILFPGDLGVAAAVALILLL 187
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 4-157 3.17e-11

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 60.90  E-value: 3.17e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547   4 MLERLWQGFLDTLLMIGASSAIVLLVGIPLALVLVTTGpggifeaRLLNRILGGLVNVLRSVPFLILMVALIpftrMIVG 83
Cdd:COG1173  70 VLSRLLYGARISLLVGLLAVLIALVIGVLLGLLAGYFG-------GWVDAVLMRLVDVLLAFPSLLLAIALV----AVLG 138

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15597547  84 TsyGVWAAVVPLTIAATPFFARI--AEV-SLREVDHglVEAAQAMGCERRHIICNVLLPEARPGIVGGFTITLVTMI 157
Cdd:COG1173 139 P--GLLNVILALGLTGWPGYARLvrAQVlSLREREY--VEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAI 211
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 6-152 2.91e-09

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 55.53  E-value: 2.91e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547   6 ERLWQGFLDTLLMIGASSAIVLLVGIPLALVLV-TTGPGgifearllNRILGGLVNVLRSVPFLILMVALI--------- 75
Cdd:COG0555  50 PRVLAALKLSLGTALIAALINLVFGLPLAWVLVrYRFPG--------KRLVDALVDLPFALPTAVAGIALLllfgpngwl 121

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15597547  76 --PFTRMIVGTSYGVWAAVVPLTIAATPFFARIAEVSLREVDHGLVEAAQAMGCERRHIICNVLLPEARPGIVGGFTIT 152
Cdd:COG0555 122 gqLLAPLGIKVAFTPLGIVLAQTFVSLPFVVRTVQPVLEELDPELEEAAATLGASRWQTFRRVILPLLLPALLTGFALA 200
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
7-159 7.40e-09

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 54.78  E-value: 7.40e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547   7 RLWQGFLDTLLMIGASSAIVLLVGIPLALVLVTTgpggifearllnRILG-GLVNVLRSVPFLI--LMVALI-------- 75
Cdd:COG1178  51 YLWRALGNTLLLALLVTLLSLLLGVPLAWLLART------------DFPGrRLLRWLLLLPLALppYVVALAwialfgpn 118

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547  76 ----PFTRMIVGTS----YGVWAAVVPLTIAATPFFARIAEVSLREVDHGLVEAAQAMGCERRHIICNVLLPEARPGIVG 147
Cdd:COG1178 119 gllnTLLRALFGLEppdiYGLGGIILVLVLFNYPYVYLLLRAALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAA 198

                       170
                ....*....|..
gi 15597547 148 GFTITLVTMINS 159
Cdd:COG1178 199 GALLVFLLCLAD 210
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 6-155 1.25e-08

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 53.58  E-value: 1.25e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547   6 ERLWQGFLDTLLMIGASSAIVLLVGIPLALVLVTTGPGGifearllNRILGGLVNVLRSVPFLILMVALIPFTRMIvGTS 85
Cdd:COG1177  57 PRLLDALLNSLLIALLSTLLATVLGTPAALALARYRFRG-------RRLLLALLLLPLVVPGIVLGVALLLLFSAL-GLS 128

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547  86 YGVWAAVVPLTIAATPFFARIAEVSLREVDHGLVEAAQAMGCERRHIICNVLLPEARPGIVGGFTITLVT 155
Cdd:COG1177 129 GGLWGLILAHVVFTLPFVVLVVLARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIAPGILAGALLAFTL 198
PhnE TIGR01097
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound ...
 5-147 1.81e-08

phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions]


Pssm-ID: 273441 [Multi-domain]  Cd Length: 250  Bit Score: 52.93  E-value: 1.81e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547     5 LERLWQGFLDTLLMIGASSAIVLLVGIPLALVlvttGPGGIFEARLLNRILGGLVNVLRSVPFLILmvALIpftrMIVGT 84
Cdd:TIGR01097  53 LPRILKALLETLAMAILGTVLAAVLAVPLALL----AARNITPSPWLYGLARLLLNFLRAIPELVW--ALI----FVAAV 122

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15597547    85 SYGVWAAVVPLTIAATPFFARIAEVSLREVDHGLVEAAQAMGCERRHIICNVLLPEARPGIVG 147
Cdd:TIGR01097 123 GLGPFAGVLALAFHTVGFLGKLFAEAIEEVDPGPVEALRATGASKLQVIRYGVLPQVLPQFLS 185
HisM COG0765
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 1-217 4.24e-08

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440528 [Multi-domain]  Cd Length: 218  Bit Score: 51.61  E-value: 4.24e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547   1 MSPMLERLWQGFLDTLLMIGASSAIVLLVGIPLALVLVTTGPggifearLLNRILGGLVNVLRSVPFLILMVaLIPFTRM 80
Cdd:COG0765   8 LLDYLPLLLEGLLVTLLLTVLAIVLGLVLGLLLALARLSPNP-------VLRWLATAYVEFFRGTPLLVQLF-FIYFGLP 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547  81 IVGTSYG-VWAAVVPLTIAATPFFARIAEVSLREVDHGLVEAAQAMGCERRHIICNVLLPEARPGIVGGFTITLVTMI-N 158
Cdd:COG0765  80 LLGIDLSpFVAAVIALTLNSAAYLAEIVRAGIQSVPKGQWEAARALGLSRWQTMRRIILPQALRIILPPLGNEFISLLkD 159

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 15597547 159 SSamagAIGAGGLGDLAYRYGYQRFDTQVMLTVIIVLVLLVTLIQFGGDRLARLLNKRL 217
Cdd:COG0765 160 TS----LVSVIGVPELTRAAQQIASRTFRPFEVYLVAALIYLVLTLPLSLLARRLERRL 214
PhnE COG3639
ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport ...
 5-147 8.81e-08

ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 442856 [Multi-domain]  Cd Length: 244  Bit Score: 50.85  E-value: 8.81e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547   5 LERLWQGFLDTLLMIGASSAIVLLVGIPLALVlvttGPGGIFEARLLNRILGGLVNVLRSVPFLILmvALIpftrMIVGT 84
Cdd:COG3639  46 LPDLLSALLETLAIALLGTLLGAVLALPLAFL----AARNLAPNPWVRLLARRLLNVLRAIPELVW--ALI----FVAAV 115

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15597547  85 SYGVWAAVVPLTIAATPFFAR-IAEvSLREVDHGLVEAAQAMGCERRHIICNVLLPEARPGIVG 147
Cdd:COG3639 116 GLGPFAGVLALAIHTIGFLGKlFAE-AIEEIDPGPVEALRATGASRLQVIRYGVLPQVLPQFLS 178
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 9-157 1.00e-06

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 48.22  E-value: 1.00e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547   9 WQGFLDTLLMIGASSAIVLLVGIPLALVLVTTGPGgifearlLNRILGGLVNVLRSVPFLILMVALI-------PFTRMI 81
Cdd:COG1176  66 LKVLLRTLWIALLTTLICLLLGYPIAYFLARAPPR-------WRNLLLLLVILPFWTSFLVRTYAWIvllgrngLLNSLL 138

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547  82 VGT---------SYGVWAAVVPLTIAATPFFARIAEVSLREVDHGLVEAAQAMGCERRHIICNVLLPEARPGIVGGFTIT 152
Cdd:COG1176 139 LALglideplrlLYTEFAVVIGLVYVYLPFMVLPLYAALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLV 218


                ....*
gi 15597547 153 LVTMI 157
Cdd:COG1176 219 FIPAL 223
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
7-158 1.12e-06

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 48.23  E-value: 1.12e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547   7 RLWQGFLDTLLMIGASSAIVLLVGIPLALVLVTTGpggifeaRLLNRILGGLVNVLRSVPFLILMVALI-PFTRMIVGTS 85
Cdd:COG1178 335 SLLRALLNSLLLALLAALLAVLLALLLAYLVRRRR-------GRLARLLDRLAMLPYAVPGIVLGLGLLlLFNRPLPLLL 407

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15597547  86 YGVWAAVV-PLTIAATPFFARIAEVSLREVDHGLVEAAQAMGCERRHIICNVLLPEARPGIVGGFTITLVTMIN 158
Cdd:COG1178 408 YGTLAILVlAYVVRFLPFALRSLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLVFVTSMK 481
phosphate_pstC TIGR02138
phosphate ABC transporter, permease protein PstC; The typical operon for the high affinity ...
 65-153 8.40e-05

phosphate ABC transporter, permease protein PstC; The typical operon for the high affinity inorganic phosphate ABC transporter encodes an ATP-binding protein, a phosphate-binding protein, and two permease proteins. This family consists of one of the two permease proteins, PstC, which is homologous to PstA (TIGR00974). In the model bacterium Escherichia coli, this transport system is induced when the concentration of extrallular inorganic phosphate is low. A constitutive, lower affinity transporter operates otherwise. [Transport and binding proteins, Anions]


Pssm-ID: 273992 [Multi-domain]  Cd Length: 295  Bit Score: 42.25  E-value: 8.40e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547    65 VPFL--ILMVALIPFTRMIVGTSYGVWAAVVPLTIAATPFFARIAEVSLREVDHGLVEAAQAMGCERRHIICNVLLPEAR 142
Cdd:TIGR02138 126 VPFLkpHFQPFLGSNLGLIPLFGGPILTAGIVLAIMILPTIASISRDALRAVPRSYKEASYALGATKWETIRRVILPAAR 205

                          90
                  ....*....|.
gi 15597547   143 PGIVGGFTITL 153
Cdd:TIGR02138 206 SGIVGAVVLGL 216
PRK09881 PRK09881
D,D-dipeptide ABC transporter permease;
29-146 9.57e-05

D,D-dipeptide ABC transporter permease;


Pssm-ID: 182131 [Multi-domain]  Cd Length: 296  Bit Score: 42.11  E-value: 9.57e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547   29 VGIPLALVLVTTGPGGIFEArlLNRILGG--------LVNVLRSVPFLILMVALIPftrmIVGTSygVWAAVVPLTIAAT 100
Cdd:PRK09881  97 ILAGLVVVAIAGMIGSLLGC--LSGVLGGradaiimrIMDIMLSIPSLVLTMALAA----ALGPS--LFNAMLAIAIVRI 168

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 15597547  101 PFFARIAE---VSLREvdHGLVEAAQAMGCERRHIICNVLLPEARPGIV 146
Cdd:PRK09881 169 PFYVRLARgqaLVVRQ--YTYVQAAKTFGASRWHLISWHILRNSLPPLI 215
PRK15050 PRK15050
2-aminoethylphosphonate transport system permease PhnU; Provisional
 15-158 3.94e-03

2-aminoethylphosphonate transport system permease PhnU; Provisional


Pssm-ID: 237888 [Multi-domain]  Cd Length: 296  Bit Score: 37.29  E-value: 3.94e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547   15 TLLMIGASSAIVLLVGIPLALVLVTTG-PGGIFEARLLNRILG-----------------GLVNvlrsvpflILMVALIP 76
Cdd:PRK15050  78 TLQIAFASTAGCLVLGVLLALVLAFVPfPGASLVGRFIDTFVAfpsflitlaftflygsaGSVN--------IALQRLFG 149

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547   77 FTRMIVGTSYGVWAAVVPLTIAATPFFARIAEVSLREVDHGLVEAAQAMGCERRHIICNVLLPEARPGIVGGFTITLVTM 156
Cdd:PRK15050 150 LEAPPLDFLYSPGGVILAEITFYTPFVVRPLLAAFAQLDARQLEAAASLGASPWRVARRVILPEAWPALAAGGSLCLLLT 229


                 ..
gi 15597547  157 IN 158
Cdd:PRK15050 230 LN 231
PRK10952 PRK10952
proline/glycine betaine ABC transporter permease ProW;
13-153 5.52e-03

proline/glycine betaine ABC transporter permease ProW;


Pssm-ID: 236805  Cd Length: 355  Bit Score: 36.99  E-value: 5.52e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547   13 LDTLLMIGA----SSAIVLLVGIPLALV--LVTTGPGGIFEARLLN--RILGGLVNVLRSVPFLILMVALIpftrMIVGT 84
Cdd:PRK10952 131 LVSLIAIGAigawSQAMVTLALVLTALLfcIVIGLPLGIWLARSPRaaKIIRPLLDAMQTTPAFVYLVPIV----MLFGI 206

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15597547   85 syGVWAAVVPLTIAATPFFARIAEVSLREVDHGLVEAAQAMGCERRHIICNVLLPEARPGIVGGFTITL 153
Cdd:PRK10952 207 --GNVPGVVVTIIFALPPIVRLTILGINQVPADLIEASRSFGASPRQMLFKVQLPLAMPTIMAGVNQTL 273
potC PRK09500
spermidine/putrescine ABC transporter membrane protein; Reviewed
 9-160 5.72e-03

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 236542 [Multi-domain]  Cd Length: 256  Bit Score: 36.89  E-value: 5.72e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547    9 WQGFL----------DTLLMIGASSAIVLLVGIPLALVLVTTGPGGIFEARLLNR-ILGGLVNVLRSVPFLILMVALIPF 77
Cdd:PRK09500  38 WKGFTtkwyellfnnDSLLQAAQHSLTMAVFSATFATLIGSLTAVALYRYRFRGKkFVSGMLFVVMMSPDIVMAISLLVL 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547   78 TrMIVGTSYGVWAAVVPLTIAATPFFARIAEVSLREVDHGLVEAAQAMGCERRHIICNVLLPEARPGIVGG----FTITL 153
Cdd:PRK09500 118 F-MLLGIQLGFWSLLFAHITFCLPFVVVTVYSRLKGFDVRMLEAAKDLGASEFTILRKIILPLALPAVAAGwllsFTLSL 196


                 ....*..
gi 15597547  154 VTMINSS 160
Cdd:PRK09500 197 DDVVVSS 203
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 8-159 6.90e-03

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 36.61  E-value: 6.90e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15597547   8 LWQGFLDTLLMIGASSAIVLLVGIPLALVLvttgpggifeARL---LNRILGGLVNVLRSVPFLILMvalIPFTRMIVGT 84
Cdd:COG0395  72 FGRYLLNSLIVAVVSTVLSLLLSSLAAYAL----------ARFrfrGRKLLFLLILATLMIPGQVLL---IPLYLLFRQL 138

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15597547  85 ----SYgvWAAVVPLTIAATPFFARIAEVSLREVDHGLVEAAQAMGCERRHIICNVLLPEARPGIVggfTITLVTMINS 159
Cdd:COG0395 139 gllnTY--WGLILPYLAFGLPFGIFLLRQFFRSIPRELEEAARIDGASEFRIFWRIVLPLSKPALA---TVAIFTFIGA 212
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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