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Conserved domains on  [gi|15598199|ref|NP_251693|]
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hypothetical protein PA3003 [Pseudomonas aeruginosa PAO1]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CsiV super family cl12546
Peptidoglycan-binding protein, CsiV; CsiV, a small periplasmic protein (cell-shape integrity ...
 24-174 4.83e-39

Peptidoglycan-binding protein, CsiV; CsiV, a small periplasmic protein (cell-shape integrity in Vibrio), is essential for growth of Vibrio cholerae in the presence of DAA, non-canonical amino-acids, the typical components of peptidoglycan side-chains in Vibrio cholerae. CsiV interacts with LpoA, the lipoprotein activator of penicillin-binding-protein1A that is necessary for mediating the assembly of peptidoglycan. CsiV acts through LpoA to promote peptidoglycan biogenesis in V. cholerae and other vibrio species as well as in the other genera where this protein is found.


The actual alignment was detected with superfamily member pfam10972:

Pssm-ID: 431567  Cd Length: 207  Bit Score: 133.31  E-value: 4.83e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598199    24 YQVELVVFRQAGDAVPSSQPAPDDWATGA--------------QPLASDALRATALDNQLAKLSQDNGYTVLLHKAWRQD 89
Cdd:pfam10972  22 YQVEVIVFRQNVPPGESAEYWPDDWPPIDseetldlltpyisqLGLLLLPESQLQLNDIAQRLEREAGYQPLLHLAWQQP 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598199    90 IGE--TPVKIALSEGQEQDHHFPV---EGTLTLSQVRFVDMEADFWVNRFGDDGFLA----------------GSQHIRQ 148
Cdd:pfam10972 102 VASrsRAPPIRIFGGEDFFDHFPVwelDGTLKIYLSRYLHIDTDLWLRRPSQKGQIEndletqepnpeesaetESYRLDQ 181

                         170       180
                  ....*....|....*....|....*.
gi 15598199   149 GTRLKNGELTYLDHPSLGILIKVVPV 174
Cdd:pfam10972 182 KRRVRSGELHYLDHPLLGVLVQIRPV 207
 
Name Accession Description Interval E-value
CsiV pfam10972
Peptidoglycan-binding protein, CsiV; CsiV, a small periplasmic protein (cell-shape integrity ...
 24-174 4.83e-39

Peptidoglycan-binding protein, CsiV; CsiV, a small periplasmic protein (cell-shape integrity in Vibrio), is essential for growth of Vibrio cholerae in the presence of DAA, non-canonical amino-acids, the typical components of peptidoglycan side-chains in Vibrio cholerae. CsiV interacts with LpoA, the lipoprotein activator of penicillin-binding-protein1A that is necessary for mediating the assembly of peptidoglycan. CsiV acts through LpoA to promote peptidoglycan biogenesis in V. cholerae and other vibrio species as well as in the other genera where this protein is found.


Pssm-ID: 431567  Cd Length: 207  Bit Score: 133.31  E-value: 4.83e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598199    24 YQVELVVFRQAGDAVPSSQPAPDDWATGA--------------QPLASDALRATALDNQLAKLSQDNGYTVLLHKAWRQD 89
Cdd:pfam10972  22 YQVEVIVFRQNVPPGESAEYWPDDWPPIDseetldlltpyisqLGLLLLPESQLQLNDIAQRLEREAGYQPLLHLAWQQP 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598199    90 IGE--TPVKIALSEGQEQDHHFPV---EGTLTLSQVRFVDMEADFWVNRFGDDGFLA----------------GSQHIRQ 148
Cdd:pfam10972 102 VASrsRAPPIRIFGGEDFFDHFPVwelDGTLKIYLSRYLHIDTDLWLRRPSQKGQIEndletqepnpeesaetESYRLDQ 181

                         170       180
                  ....*....|....*....|....*.
gi 15598199   149 GTRLKNGELTYLDHPSLGILIKVVPV 174
Cdd:pfam10972 182 KRRVRSGELHYLDHPLLGVLVQIRPV 207
 
Name Accession Description Interval E-value
CsiV pfam10972
Peptidoglycan-binding protein, CsiV; CsiV, a small periplasmic protein (cell-shape integrity ...
 24-174 4.83e-39

Peptidoglycan-binding protein, CsiV; CsiV, a small periplasmic protein (cell-shape integrity in Vibrio), is essential for growth of Vibrio cholerae in the presence of DAA, non-canonical amino-acids, the typical components of peptidoglycan side-chains in Vibrio cholerae. CsiV interacts with LpoA, the lipoprotein activator of penicillin-binding-protein1A that is necessary for mediating the assembly of peptidoglycan. CsiV acts through LpoA to promote peptidoglycan biogenesis in V. cholerae and other vibrio species as well as in the other genera where this protein is found.


Pssm-ID: 431567  Cd Length: 207  Bit Score: 133.31  E-value: 4.83e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598199    24 YQVELVVFRQAGDAVPSSQPAPDDWATGA--------------QPLASDALRATALDNQLAKLSQDNGYTVLLHKAWRQD 89
Cdd:pfam10972  22 YQVEVIVFRQNVPPGESAEYWPDDWPPIDseetldlltpyisqLGLLLLPESQLQLNDIAQRLEREAGYQPLLHLAWQQP 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598199    90 IGE--TPVKIALSEGQEQDHHFPV---EGTLTLSQVRFVDMEADFWVNRFGDDGFLA----------------GSQHIRQ 148
Cdd:pfam10972 102 VASrsRAPPIRIFGGEDFFDHFPVwelDGTLKIYLSRYLHIDTDLWLRRPSQKGQIEndletqepnpeesaetESYRLDQ 181

                         170       180
                  ....*....|....*....|....*.
gi 15598199   149 GTRLKNGELTYLDHPSLGILIKVVPV 174
Cdd:pfam10972 182 KRRVRSGELHYLDHPLLGVLVQIRPV 207
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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