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Conserved domains on  [gi|15598223|ref|NP_251717|]
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transcriptional regulator [Pseudomonas aeruginosa PAO1]

Protein Classification

AraC family transcriptional regulator( domain architecture ID 12117664)

AraC family transcriptional regulator containing an AraC family helix-turn-helix (HTH) DNA-binding domain and an N-terminal arabinose binding domain, may regulate the expression of genes with diverse biological functions including metabolism, stress response, and virulence

CATH:  1.10.10.10
Gene Ontology:  GO:0003677|GO:0006355|GO:0003700
PubMed:  12596232|10473770|15808743|9409145|33837749|11282467

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Arabinose_bd pfam12625
Arabinose-binding domain of AraC transcription regulator, N-term; AraC is a bacterial ...
 23-208 8.61e-51

Arabinose-binding domain of AraC transcription regulator, N-term; AraC is a bacterial transcriptional regulatory protein with a DNA-binding domain at the C-terminus, HTH_AraC, pfam00165, and this dimerization domain which harbours the arabinose-binding pocket at the N-terminus. AraC positively and negatively regulates expression of the proteins required for the uptake and catabolism of the sugar L-arabinose 1,2,3].


:

Pssm-ID: 432679  Cd Length: 185  Bit Score: 167.05  E-value: 8.61e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598223    23 GLDIAPALAAAGLQADQLNDNRQRLPGEAHEHLLGYFCEHSGDPLFGLHSARFVQPGSWSVLGYIAMNCATLGEAMSRIT 102
Cdd:pfam12625   1 GLDPAALLRRAGLDPALLADPDARVPLDQYLRLWEAAARELGDPALGLRLGRRLRPGSLGLLGYAALSSPTLGEALDRLL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598223   103 PYEKLVGDMGTSRI-EAAGGQVRLIWNCRHQTPLVRRHMVEHVLASWVLYARWIADLEGSPDEVWLEHDLPDgtRVEDYE 181
Cdd:pfam12625  81 RYLRLLSDALELRLeEGEGGLARLRLDVRPIPGRRRDFLLELALAALLRLARWLLGRRLPPLRVEFPHPAPA--DAAEYE 158

                         170       180
                  ....*....|....*....|....*..
gi 15598223   182 TFFGCPVRFAQPCSALLVPLDYLALPL 208
Cdd:pfam12625 159 RLFGCPVRFGAPRNALVFDAADLDRPL 185
AraC COG2207
AraC-type DNA-binding domain and AraC-containing proteins [Transcription];
130-341 1.03e-21

AraC-type DNA-binding domain and AraC-containing proteins [Transcription];


:

Pssm-ID: 441809 [Multi-domain]  Cd Length: 258  Bit Score: 92.92  E-value: 1.03e-21
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598223 130 RHQTPLVRRHMVEHVLASWVLYARWIADLEGSPDEVWLEHDLPDGTRVEDYETFFGCPVRFAQPCSALLVPLDYLALPLR 209
Cdd:COG2207  46 LLLLLLGLLGGLLLLLLLLLLLGLLLLLLLLLLGLLLLALLALLLLVGLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL 125

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598223 210 QADATLLRTLEEHALALMAELDDDEPLPLRVKNALRQLLKDGLPRKERVAEKFGMTVRTLQRHLQQA-GSSYQQTLDELR 288
Cdd:COG2207 126 LLLALLRALELLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLTLEELARELGLSPRTLSRLFKEEtGTSPKQYLRELR 205

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|...
gi 15598223 289 RELAEHYLLHSELPIQDIAQYLGFTESRSFHRSFKGWTGQTPGEYRQRRKEPA 341
Cdd:COG2207 206 LERAKRLLAETDLSISEIAYELGFSSQSHFSRAFKKRFGVTPSEYRKRLRARA 258
 
Name Accession Description Interval E-value
Arabinose_bd pfam12625
Arabinose-binding domain of AraC transcription regulator, N-term; AraC is a bacterial ...
 23-208 8.61e-51

Arabinose-binding domain of AraC transcription regulator, N-term; AraC is a bacterial transcriptional regulatory protein with a DNA-binding domain at the C-terminus, HTH_AraC, pfam00165, and this dimerization domain which harbours the arabinose-binding pocket at the N-terminus. AraC positively and negatively regulates expression of the proteins required for the uptake and catabolism of the sugar L-arabinose 1,2,3].


Pssm-ID: 432679  Cd Length: 185  Bit Score: 167.05  E-value: 8.61e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598223    23 GLDIAPALAAAGLQADQLNDNRQRLPGEAHEHLLGYFCEHSGDPLFGLHSARFVQPGSWSVLGYIAMNCATLGEAMSRIT 102
Cdd:pfam12625   1 GLDPAALLRRAGLDPALLADPDARVPLDQYLRLWEAAARELGDPALGLRLGRRLRPGSLGLLGYAALSSPTLGEALDRLL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598223   103 PYEKLVGDMGTSRI-EAAGGQVRLIWNCRHQTPLVRRHMVEHVLASWVLYARWIADLEGSPDEVWLEHDLPDgtRVEDYE 181
Cdd:pfam12625  81 RYLRLLSDALELRLeEGEGGLARLRLDVRPIPGRRRDFLLELALAALLRLARWLLGRRLPPLRVEFPHPAPA--DAAEYE 158

                         170       180
                  ....*....|....*....|....*..
gi 15598223   182 TFFGCPVRFAQPCSALLVPLDYLALPL 208
Cdd:pfam12625 159 RLFGCPVRFGAPRNALVFDAADLDRPL 185
AraC COG2207
AraC-type DNA-binding domain and AraC-containing proteins [Transcription];
130-341 1.03e-21

AraC-type DNA-binding domain and AraC-containing proteins [Transcription];


Pssm-ID: 441809 [Multi-domain]  Cd Length: 258  Bit Score: 92.92  E-value: 1.03e-21
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598223 130 RHQTPLVRRHMVEHVLASWVLYARWIADLEGSPDEVWLEHDLPDGTRVEDYETFFGCPVRFAQPCSALLVPLDYLALPLR 209
Cdd:COG2207  46 LLLLLLGLLGGLLLLLLLLLLLGLLLLLLLLLLGLLLLALLALLLLVGLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL 125

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598223 210 QADATLLRTLEEHALALMAELDDDEPLPLRVKNALRQLLKDGLPRKERVAEKFGMTVRTLQRHLQQA-GSSYQQTLDELR 288
Cdd:COG2207 126 LLLALLRALELLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLTLEELARELGLSPRTLSRLFKEEtGTSPKQYLRELR 205

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|...
gi 15598223 289 RELAEHYLLHSELPIQDIAQYLGFTESRSFHRSFKGWTGQTPGEYRQRRKEPA 341
Cdd:COG2207 206 LERAKRLLAETDLSISEIAYELGFSSQSHFSRAFKKRFGVTPSEYRKRLRARA 258
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
256-334 3.09e-20

helix_turn_helix, arabinose operon control protein;


Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 83.76  E-value: 3.09e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598223    256 ERVAEKFGMTVRTLQRHLQQA-GSSYQQTLDELRRELAEHYLLHSELPIQDIAQYLGFTESRSFHRSFKGWTGQTPGEYR 334
Cdd:smart00342   5 EDLAEALGVSPRHLQRLFKKEtGTTPKQYLRDRRLERARRLLRDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTPSEYR 84
HTH_18 pfam12833
Helix-turn-helix domain;
258-336 2.35e-19

Helix-turn-helix domain;


Pssm-ID: 432818 [Multi-domain]  Cd Length: 81  Bit Score: 81.10  E-value: 2.35e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598223   258 VAEKFGMTVRTLQRHLQQA-GSSYQQTLDELRRELAEHYLLH-SELPIQDIAQYLGFTESRSFHRSFKGWTGQTPGEYRQ 335
Cdd:pfam12833   1 LAAALGMSPRTLSRLFKRElGLSPKEYLRRLRLERARRLLLEdTGLSVAEIALALGFSDASHFSRAFRRLFGLTPSEYRR 80


                  .
gi 15598223   336 R 336
Cdd:pfam12833  81 R 81
PRK13503 PRK13503
HTH-type transcriptional activator RhaS;
256-337 1.41e-10

HTH-type transcriptional activator RhaS;


Pssm-ID: 184094 [Multi-domain]  Cd Length: 278  Bit Score: 61.23  E-value: 1.41e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598223  256 ERVAEKFGMTVRTLQRHL-QQAGSSYQQTLDELRRELAEHYLLHSELPIQDIAQYLGFTESRSFHRSFKGWTGQTPGEYR 334
Cdd:PRK13503 191 EALADQFSLSLRTLHRQLkQQTGLTPQRYLNRLRLLKARHLLRHSDASVTDIAYRCGFGDSNHFSTLFRREFSWSPRDIR 270


                 ...
gi 15598223  335 QRR 337
Cdd:PRK13503 271 QGR 273
 
Name Accession Description Interval E-value
Arabinose_bd pfam12625
Arabinose-binding domain of AraC transcription regulator, N-term; AraC is a bacterial ...
 23-208 8.61e-51

Arabinose-binding domain of AraC transcription regulator, N-term; AraC is a bacterial transcriptional regulatory protein with a DNA-binding domain at the C-terminus, HTH_AraC, pfam00165, and this dimerization domain which harbours the arabinose-binding pocket at the N-terminus. AraC positively and negatively regulates expression of the proteins required for the uptake and catabolism of the sugar L-arabinose 1,2,3].


Pssm-ID: 432679  Cd Length: 185  Bit Score: 167.05  E-value: 8.61e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598223    23 GLDIAPALAAAGLQADQLNDNRQRLPGEAHEHLLGYFCEHSGDPLFGLHSARFVQPGSWSVLGYIAMNCATLGEAMSRIT 102
Cdd:pfam12625   1 GLDPAALLRRAGLDPALLADPDARVPLDQYLRLWEAAARELGDPALGLRLGRRLRPGSLGLLGYAALSSPTLGEALDRLL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598223   103 PYEKLVGDMGTSRI-EAAGGQVRLIWNCRHQTPLVRRHMVEHVLASWVLYARWIADLEGSPDEVWLEHDLPDgtRVEDYE 181
Cdd:pfam12625  81 RYLRLLSDALELRLeEGEGGLARLRLDVRPIPGRRRDFLLELALAALLRLARWLLGRRLPPLRVEFPHPAPA--DAAEYE 158

                         170       180
                  ....*....|....*....|....*..
gi 15598223   182 TFFGCPVRFAQPCSALLVPLDYLALPL 208
Cdd:pfam12625 159 RLFGCPVRFGAPRNALVFDAADLDRPL 185
AraC COG2207
AraC-type DNA-binding domain and AraC-containing proteins [Transcription];
130-341 1.03e-21

AraC-type DNA-binding domain and AraC-containing proteins [Transcription];


Pssm-ID: 441809 [Multi-domain]  Cd Length: 258  Bit Score: 92.92  E-value: 1.03e-21
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598223 130 RHQTPLVRRHMVEHVLASWVLYARWIADLEGSPDEVWLEHDLPDGTRVEDYETFFGCPVRFAQPCSALLVPLDYLALPLR 209
Cdd:COG2207  46 LLLLLLGLLGGLLLLLLLLLLLGLLLLLLLLLLGLLLLALLALLLLVGLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL 125

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598223 210 QADATLLRTLEEHALALMAELDDDEPLPLRVKNALRQLLKDGLPRKERVAEKFGMTVRTLQRHLQQA-GSSYQQTLDELR 288
Cdd:COG2207 126 LLLALLRALELLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLTLEELARELGLSPRTLSRLFKEEtGTSPKQYLRELR 205

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|...
gi 15598223 289 RELAEHYLLHSELPIQDIAQYLGFTESRSFHRSFKGWTGQTPGEYRQRRKEPA 341
Cdd:COG2207 206 LERAKRLLAETDLSISEIAYELGFSSQSHFSRAFKKRFGVTPSEYRKRLRARA 258
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
256-334 3.09e-20

helix_turn_helix, arabinose operon control protein;


Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 83.76  E-value: 3.09e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598223    256 ERVAEKFGMTVRTLQRHLQQA-GSSYQQTLDELRRELAEHYLLHSELPIQDIAQYLGFTESRSFHRSFKGWTGQTPGEYR 334
Cdd:smart00342   5 EDLAEALGVSPRHLQRLFKKEtGTTPKQYLRDRRLERARRLLRDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTPSEYR 84
HTH_18 pfam12833
Helix-turn-helix domain;
258-336 2.35e-19

Helix-turn-helix domain;


Pssm-ID: 432818 [Multi-domain]  Cd Length: 81  Bit Score: 81.10  E-value: 2.35e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598223   258 VAEKFGMTVRTLQRHLQQA-GSSYQQTLDELRRELAEHYLLH-SELPIQDIAQYLGFTESRSFHRSFKGWTGQTPGEYRQ 335
Cdd:pfam12833   1 LAAALGMSPRTLSRLFKRElGLSPKEYLRRLRLERARRLLLEdTGLSVAEIALALGFSDASHFSRAFRRLFGLTPSEYRR 80


                  .
gi 15598223   336 R 336
Cdd:pfam12833  81 R 81
GlxA COG4977
Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH ...
 204-343 1.16e-14

Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH domain [Transcription];


Pssm-ID: 444002 [Multi-domain]  Cd Length: 318  Bit Score: 73.65  E-value: 1.16e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598223 204 LALPLRQADATLLRtleehALALMAElDDDEPLPLrvknalrqllkdglprkERVAEKFGMTVRTLQRHLQQA-GSSYQQ 282
Cdd:COG4977 201 LLVPLGHRDPRLAR-----AQAWMEA-NLEEPLSV-----------------DELARRAGMSPRTLERRFRAAtGTTPAR 257

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15598223 283 TLDELRRELAEHYLLHSELPIQDIAQYLGFTESRSFHRSFKGWTGQTPGEYRQRRKEPAAQ 343
Cdd:COG4977 258 YLQRLRLERARRLLETTDLSIEEIAAACGFGSASHFRRAFRRRFGVSPSAYRRRFRARAAA 318
PRK13503 PRK13503
HTH-type transcriptional activator RhaS;
256-337 1.41e-10

HTH-type transcriptional activator RhaS;


Pssm-ID: 184094 [Multi-domain]  Cd Length: 278  Bit Score: 61.23  E-value: 1.41e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598223  256 ERVAEKFGMTVRTLQRHL-QQAGSSYQQTLDELRRELAEHYLLHSELPIQDIAQYLGFTESRSFHRSFKGWTGQTPGEYR 334
Cdd:PRK13503 191 EALADQFSLSLRTLHRQLkQQTGLTPQRYLNRLRLLKARHLLRHSDASVTDIAYRCGFGDSNHFSTLFRREFSWSPRDIR 270


                 ...
gi 15598223  335 QRR 337
Cdd:PRK13503 271 QGR 273
AdaA COG2169
Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), ...
 240-338 3.30e-07

Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains [Replication, recombination and repair];


Pssm-ID: 441772 [Multi-domain]  Cd Length: 358  Bit Score: 51.21  E-value: 3.30e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598223 240 VKNALRqLLKDGLPRKERV---AEKFGMTVRTLQRHLQQA-GSSYQQTLDELRRELAEHyLLHSELPIQDIAQYLGFTES 315
Cdd:COG2169  86 VARACR-LIEAGAEDRPSLedlAARLGLSPRHLRRLFKAHtGVTPKAYARARRLLRARQ-LLQTGLSVTDAAYAAGFGSL 163

                        90       100
                ....*....|....*....|...
gi 15598223 316 RSFHRSFKGWTGQTPGEYRQRRK 338
Cdd:COG2169 164 SRFYEAFKKLLGMTPSAYRRGGA 186
HTH_AraC pfam00165
Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the ...
 291-335 3.35e-06

Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the N-terminal arm of AraC binds to the DNA binding domain (pfam00165) and helps to hold the two DNA binding domains in a relative orientation that favours DNA looping. In the presence of arabinose, the arms bind over the arabinose on the dimerization domain, thus freeing the DNA-binding domains. The freed DNA-binding domains are then able to assume a conformation suitable for binding to the adjacent DNA sites that are utilized when AraC activates transcription, and hence AraC ceases looping the DNA when arabinose is added.


Pssm-ID: 425497 [Multi-domain]  Cd Length: 42  Bit Score: 43.30  E-value: 3.35e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 15598223   291 LAEHYllHSELPIQDIAQYLGFTESrSFHRSFKGWTGQTPGEYRQ 335
Cdd:pfam00165   1 LRENL--STNLTIADIADELGFSRS-YFSRLFKKYTGVTPSQYRH 42
ftrA PRK09393
transcriptional activator FtrA; Provisional
 257-336 3.38e-06

transcriptional activator FtrA; Provisional


Pssm-ID: 181818 [Multi-domain]  Cd Length: 322  Bit Score: 48.04  E-value: 3.38e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598223  257 RVAEKFGMTVRTLQRHLQQAG--SSYQQTLDElRRELAEHYLLHSELPIQDIAQYLGFTESRSFHRSFKGWTGQTPGEYR 334
Cdd:PRK09393 239 SLAARAAMSPRTFLRRFEAATgmTPAEWLLRE-RLARARDLLESSALSIDQIAERAGFGSEESLRHHFRRRAATSPAAYR 317


                 ..
gi 15598223  335 QR 336
Cdd:PRK09393 318 KR 319
PRK09685 PRK09685
DNA-binding transcriptional activator FeaR; Provisional
 208-336 3.73e-06

DNA-binding transcriptional activator FeaR; Provisional


Pssm-ID: 236612 [Multi-domain]  Cd Length: 302  Bit Score: 47.72  E-value: 3.73e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598223  208 LRQADATLLR-TLEEHalalmaelDDDEPLPLRVKNALRQLLKDGLP----RKERVAEKFGMTVRTLQRHLQQAGSSYQQ 282
Cdd:PRK09685 173 LLEALIALLRpALHQR--------ESVQPRRERQFQKVVALIDQSIQeeilRPEWIAGELGISVRSLYRLFAEQGLVVAQ 244

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 15598223  283 TLDELRRELAEHYL--LHSELPIQDIAQYLGFTESRSFHRSFKGWTGQTPGEYRQR 336
Cdd:PRK09685 245 YIRNRRLDRCADDLrpAADDEKITSIAYKWGFSDSSHFSTAFKQRFGVSPGEYRRK 300
PRK10219 PRK10219
superoxide response transcriptional regulator SoxS;
256-336 4.05e-06

superoxide response transcriptional regulator SoxS;


Pssm-ID: 182314 [Multi-domain]  Cd Length: 107  Bit Score: 44.92  E-value: 4.05e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598223  256 ERVAEKFGMTVRTLQRHLQqagSSYQQTLDELRRE----LAEHYLLHSELPIQDIAQYLGFTESRSFHRSFKGWTGQTPG 331
Cdd:PRK10219  25 DVVAKKSGYSKWYLQRMFR---TVTHQTLGDYIRQrrllLAAVELRTTERPIFDIAMDLGYVSQQTFSRVFRRQFDRTPS 101


                 ....*
gi 15598223  332 EYRQR 336
Cdd:PRK10219 102 DYRHR 106
PRK09978 PRK09978
DNA-binding transcriptional regulator GadX; Provisional
 257-339 3.46e-05

DNA-binding transcriptional regulator GadX; Provisional


Pssm-ID: 137624 [Multi-domain]  Cd Length: 274  Bit Score: 44.92  E-value: 3.46e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598223  257 RVAEKFGMTVRTLQRHLQQAGSSYQQTLDELRRELAEHYLLHSELPIQDIAQYLGFTESRSFHRSFKGWTGQTPGEYRQR 336
Cdd:PRK09978 163 RIASELLMSPSLLKKKLREEETSYSQLLTECRMQRALQLIVIHGFSIKRVAVSCGYHSVSYFIYVFRNYYGMTPTEYQER 242


                 ...
gi 15598223  337 RKE 339
Cdd:PRK09978 243 SAQ 245
PRK10572 PRK10572
arabinose operon transcriptional regulator AraC;
272-339 3.70e-05

arabinose operon transcriptional regulator AraC;


Pssm-ID: 236717 [Multi-domain]  Cd Length: 290  Bit Score: 44.96  E-value: 3.70e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598223  272 HL--QQAGSSYQQTLDELRRELAEHYLLHSELPIQDIAQYLGFTESRSFHRSFKGWTGQTPGEYRQRRKE 339
Cdd:PRK10572 218 HLfrQQLGISVLRWREDQRISRAKLLLQTTRMPIATIGRNVGYDDQLYFSRVFKKCTGASPSEFRARCEE 287
PRK13500 PRK13500
HTH-type transcriptional activator RhaR;
270-335 3.89e-05

HTH-type transcriptional activator RhaR;


Pssm-ID: 184091 [Multi-domain]  Cd Length: 312  Bit Score: 44.71  E-value: 3.89e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15598223  270 QRHLQQAGSSYQQTLDELRRELAEHYLLHSELPIQDIAQYLGFTESRSFHRSFKGWTGQTPGEYRQ 335
Cdd:PRK13500 241 QQFRQQTGMTINQYLRQVRVCHAQYLLQHSRLLISDISTECGFEDSNYFSVVFTRETGMTPSQWRH 306
PRK13502 PRK13502
HTH-type transcriptional activator RhaR;
215-335 5.38e-05

HTH-type transcriptional activator RhaR;


Pssm-ID: 184093 [Multi-domain]  Cd Length: 282  Bit Score: 44.27  E-value: 5.38e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598223  215 LLRTLEEHALAlmaelDDDEPLPLR--VKNALRQLLKDGLPRK---ERVAEKFGMTVRTL-QRHLQQAGSSYQQTLDELR 288
Cdd:PRK13502 155 LVMTLKRHRYA-----TDDLPATSRetLLDKLITALANSLECPfalDAFCQQEQCSERVLrQQFRAQTGMTINQYLRQVR 229

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 15598223  289 RELAEHYLLHSELPIQDIAQYLGFTESRSFHRSFKGWTGQTPGEYRQ 335
Cdd:PRK13502 230 ICHAQYLLQHSPLMISEISMQCGFEDSNYFSVVFTRETGMTPSQWRH 276
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
300-343 8.22e-04

helix_turn_helix, arabinose operon control protein;


Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 37.92  E-value: 8.22e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*
gi 15598223    300 ELPIQDIAQYLGFTEsRSFHRSFKGWTGQTPGEY-RQRRKEPAAQ 343
Cdd:smart00342   1 PLTLEDLAEALGVSP-RHLQRLFKKETGTTPKQYlRDRRLERARR 44
PRK13501 PRK13501
HTH-type transcriptional activator RhaR;
274-336 8.88e-04

HTH-type transcriptional activator RhaR;


Pssm-ID: 184092 [Multi-domain]  Cd Length: 290  Bit Score: 40.66  E-value: 8.88e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15598223  274 QQAGSSYQQTLDELRRELAEHYLLHSELPIQDIAQYLGFTESRSFHRSFKGWTGQTPGEYRQR 336
Cdd:PRK13501 215 QQTGMSISHYLRQIRLCHAKCLLRGSEHRISDIAARCGFEDSNYFSAVFTREAGMTPRDYRQR 277
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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