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Conserved domains on  [gi|15598294|ref|NP_251788|]
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type II secretion system protein J [Pseudomonas aeruginosa PAO1]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
T2SSJ super family cl42010
Type II secretion system (T2SS), protein J; The T2SJ proteins are pseudopilins, which are ...
 5-200 1.78e-97

Type II secretion system (T2SS), protein J; The T2SJ proteins are pseudopilins, which are targeted to the membrane in E. Coli. T2SJ forms a complex with T2SI (pfam02501) and T2SK (pfam03934) which is part of the Type II secretion apparatus involved in the translocation of proteins across the outer membrane in E.coli. The T2SK-I-J complex has quasihelical characteriztics.


The actual alignment was detected with superfamily member TIGR01711:

Pssm-ID: 455355 [Multi-domain]  Cd Length: 192  Bit Score: 282.57  E-value: 1.78e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598294     5 RGFTLLELLIAIAIFALLALATYRMFDSVMQTDQATRVQEQRMRELVRAMGALERDLTQAVERPVRDELG----DNRGAF 80
Cdd:TIGR01711   1 RGFTLLELLVAIAIFASLSLGAYQVLDSVMQSDEATRVQEARLRELQRAMGAMERDLTQMVERPVRDDGEaseqDLRGAF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598294    81 LSEGENDQIVEFTRGGWRNPLGQ-ARSRLQRVRWSLSGETLERRYWLVLDRAQDSKPRVQQVLDGVTALSWRFLDKeHNW 159
Cdd:TIGR01711  81 LSEGSDDQGVEFTRGGWRNPLGQqPRSRLQRVGWRLSGETLERRYWLYPDRAQGSKPRIQPVLDGVTALSWRFYDK-GNW 159

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 15598294   160 QGHWPTDegseeerlESLPLAVEMTLEHRHYGKLVRVWRLL 200
Cdd:TIGR01711 160 QGEWPTD--------NSLPLAVEVTLELRDYGKLVRVWLLG 192
 
Name Accession Description Interval E-value
gspJ TIGR01711
type II secretion system protein J; This model represents GspJ, one of two proteins highly ...
 5-200 1.78e-97

type II secretion system protein J; This model represents GspJ, one of two proteins highly conserved at their N-termini and described by pfam02501 but easily separable phylogenetically. The other is GspI. Both GspI and GspJ are proteins of the type II secretion pathway, or main terminal branch of the general secretion pathway. This pathway carries proteins across the outer membrane. Note that proteins of type II secretion are cryptic in E. coli K-12 - present but not yet demonstrated to act on any target.


Pssm-ID: 130772 [Multi-domain]  Cd Length: 192  Bit Score: 282.57  E-value: 1.78e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598294     5 RGFTLLELLIAIAIFALLALATYRMFDSVMQTDQATRVQEQRMRELVRAMGALERDLTQAVERPVRDELG----DNRGAF 80
Cdd:TIGR01711   1 RGFTLLELLVAIAIFASLSLGAYQVLDSVMQSDEATRVQEARLRELQRAMGAMERDLTQMVERPVRDDGEaseqDLRGAF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598294    81 LSEGENDQIVEFTRGGWRNPLGQ-ARSRLQRVRWSLSGETLERRYWLVLDRAQDSKPRVQQVLDGVTALSWRFLDKeHNW 159
Cdd:TIGR01711  81 LSEGSDDQGVEFTRGGWRNPLGQqPRSRLQRVGWRLSGETLERRYWLYPDRAQGSKPRIQPVLDGVTALSWRFYDK-GNW 159

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 15598294   160 QGHWPTDegseeerlESLPLAVEMTLEHRHYGKLVRVWRLL 200
Cdd:TIGR01711 160 QGEWPTD--------NSLPLAVEVTLELRDYGKLVRVWLLG 192
T2SSJ pfam11612
Type II secretion system (T2SS), protein J; The T2SJ proteins are pseudopilins, which are ...
 57-197 3.31e-47

Type II secretion system (T2SS), protein J; The T2SJ proteins are pseudopilins, which are targeted to the membrane in E. Coli. T2SJ forms a complex with T2SI (pfam02501) and T2SK (pfam03934) which is part of the Type II secretion apparatus involved in the translocation of proteins across the outer membrane in E.coli. The T2SK-I-J complex has quasihelical characteriztics.


Pssm-ID: 431959  Cd Length: 137  Bit Score: 152.86  E-value: 3.31e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598294    57 LERDLTQAVERPVRDELGDNRGAFLSE--GENDQIVEFTRGGWRNPLGQARSRLQRVRWSLSGETLERRYWLVLDRAQDS 134
Cdd:pfam11612   1 LERDLSQAVPRPVRDAGGDPAPAFAGRglDSDDPGLEFTRLGWPNPDGAPRSELQRVGYRLEDGRLERLTWPYLDGAVGQ 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15598294   135 KPRVQQVLDGVTALSWRFLDKEhNWQGHWPTDEGSeeerlESLPLAVEMTLEHRHYGKLVRVW 197
Cdd:pfam11612  81 EPQVQVLLDGVESLRLRFLDDG-QWQDRWPPAAAD-----QALPRAVEITLELKDGGEIRRLF 137
PulJ COG4795
Type II secretory pathway, PulJ/GspJ component [Intracellular trafficking, secretion, and ...
 1-121 7.44e-35

Type II secretory pathway, PulJ/GspJ component [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443823 [Multi-domain]  Cd Length: 118  Bit Score: 120.50  E-value: 7.44e-35
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598294   1 MRLQRGFTLLELLIAIAIFALLALATYRMFDSVMQTDQATRVQEQRMRELVRAMGALERDLTQAVERPvrDELGDNRGAF 80
Cdd:COG4795   5 RRRQRGFTLLELLVALAIFALLLLAAYRGLDSVLRSRERLEQQAERLQELQRALALLERDLRQAGPRP--DEGGDPEPAL 82

                        90       100       110       120
                ....*....|....*....|....*....|....*....|.
gi 15598294  81 lsEGENDQIVEFTRGGWRNPLgqaRSRLQRVRWSLSGETLE 121
Cdd:COG4795  83 --SGGGSCLIDLNRNGWWNPL---RSELQRVGYRLRDGALE 118
PRK10557 PRK10557
prepilin peptidase-dependent protein;
4-64 1.88e-04

prepilin peptidase-dependent protein;


Pssm-ID: 236714  Cd Length: 192  Bit Score: 41.12  E-value: 1.88e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15598294    4 QRGFTLLELLIAIAIFALLALATYRMF----DSVMQTDQATRVQEqrmrELVRAMGALERDLTQA 64
Cdd:PRK10557   6 QRGFSLLEVLLAMAIGSVLLLGAARFLpalqRQILTLTRQLRLED----EIWQRVFTVEKDLRRA 66
T4P_ComGE NF041013
competence type IV pilus minor pilin ComGE;
5-85 1.34e-03

competence type IV pilus minor pilin ComGE;


Pssm-ID: 468942 [Multi-domain]  Cd Length: 83  Bit Score: 36.79  E-value: 1.34e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598294    5 RGFTLLELLIAIAIFALLALATYRMFDSVMQTDQATRVQEQRMRELVRAMGALERDLTQAvERPVRDELGDNRGAFLSEG 84
Cdd:NF041013   4 KGFILLESLVALALLALIVSLLLPSLTQIQKEREEIKQKEEALQVLYEALQTYQLHLELN-GVEITVERSNTQIKVYWEG 82


                 .
gi 15598294   85 E 85
Cdd:NF041013  83 K 83
pilin_ComGF NF041002
competence type IV pilus minor pilin ComGF; ComGF is one of several minor pilins in the type ...
 4-86 2.52e-03

competence type IV pilus minor pilin ComGF; ComGF is one of several minor pilins in the type IV pilus involved in the competence system of natural transformation by various Gram-positive bacteria. Oddly, while nearly all members have an N-terminal region with a consensus site for cleavage and methylation, ComGF from Bacillus subtilis appears N-terminally truncated, and may be functional despite the truncation.


Pssm-ID: 468931 [Multi-domain]  Cd Length: 138  Bit Score: 37.21  E-value: 2.52e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598294    4 QRGFTLLELLIAIAIFALLALATYRMFDSVMQTDQATRVQEQrmRELVRAMGALERDLTQAVERPVRDELGDNRGAFLSE 83
Cdd:NF041002   1 EKGFTLLECLVALLVLSLILLLIPLLIKLLLKVEQYLNNSDQ--LEWLLFLQQLESELKESTFKVKNNKLYVKLDLIKSN 78


                 ...
gi 15598294   84 GEN 86
Cdd:NF041002  79 GKT 81
 
Name Accession Description Interval E-value
gspJ TIGR01711
type II secretion system protein J; This model represents GspJ, one of two proteins highly ...
 5-200 1.78e-97

type II secretion system protein J; This model represents GspJ, one of two proteins highly conserved at their N-termini and described by pfam02501 but easily separable phylogenetically. The other is GspI. Both GspI and GspJ are proteins of the type II secretion pathway, or main terminal branch of the general secretion pathway. This pathway carries proteins across the outer membrane. Note that proteins of type II secretion are cryptic in E. coli K-12 - present but not yet demonstrated to act on any target.


Pssm-ID: 130772 [Multi-domain]  Cd Length: 192  Bit Score: 282.57  E-value: 1.78e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598294     5 RGFTLLELLIAIAIFALLALATYRMFDSVMQTDQATRVQEQRMRELVRAMGALERDLTQAVERPVRDELG----DNRGAF 80
Cdd:TIGR01711   1 RGFTLLELLVAIAIFASLSLGAYQVLDSVMQSDEATRVQEARLRELQRAMGAMERDLTQMVERPVRDDGEaseqDLRGAF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598294    81 LSEGENDQIVEFTRGGWRNPLGQ-ARSRLQRVRWSLSGETLERRYWLVLDRAQDSKPRVQQVLDGVTALSWRFLDKeHNW 159
Cdd:TIGR01711  81 LSEGSDDQGVEFTRGGWRNPLGQqPRSRLQRVGWRLSGETLERRYWLYPDRAQGSKPRIQPVLDGVTALSWRFYDK-GNW 159

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 15598294   160 QGHWPTDegseeerlESLPLAVEMTLEHRHYGKLVRVWRLL 200
Cdd:TIGR01711 160 QGEWPTD--------NSLPLAVEVTLELRDYGKLVRVWLLG 192
T2SSJ pfam11612
Type II secretion system (T2SS), protein J; The T2SJ proteins are pseudopilins, which are ...
 57-197 3.31e-47

Type II secretion system (T2SS), protein J; The T2SJ proteins are pseudopilins, which are targeted to the membrane in E. Coli. T2SJ forms a complex with T2SI (pfam02501) and T2SK (pfam03934) which is part of the Type II secretion apparatus involved in the translocation of proteins across the outer membrane in E.coli. The T2SK-I-J complex has quasihelical characteriztics.


Pssm-ID: 431959  Cd Length: 137  Bit Score: 152.86  E-value: 3.31e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598294    57 LERDLTQAVERPVRDELGDNRGAFLSE--GENDQIVEFTRGGWRNPLGQARSRLQRVRWSLSGETLERRYWLVLDRAQDS 134
Cdd:pfam11612   1 LERDLSQAVPRPVRDAGGDPAPAFAGRglDSDDPGLEFTRLGWPNPDGAPRSELQRVGYRLEDGRLERLTWPYLDGAVGQ 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15598294   135 KPRVQQVLDGVTALSWRFLDKEhNWQGHWPTDEGSeeerlESLPLAVEMTLEHRHYGKLVRVW 197
Cdd:pfam11612  81 EPQVQVLLDGVESLRLRFLDDG-QWQDRWPPAAAD-----QALPRAVEITLELKDGGEIRRLF 137
PulJ COG4795
Type II secretory pathway, PulJ/GspJ component [Intracellular trafficking, secretion, and ...
 1-121 7.44e-35

Type II secretory pathway, PulJ/GspJ component [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443823 [Multi-domain]  Cd Length: 118  Bit Score: 120.50  E-value: 7.44e-35
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598294   1 MRLQRGFTLLELLIAIAIFALLALATYRMFDSVMQTDQATRVQEQRMRELVRAMGALERDLTQAVERPvrDELGDNRGAF 80
Cdd:COG4795   5 RRRQRGFTLLELLVALAIFALLLLAAYRGLDSVLRSRERLEQQAERLQELQRALALLERDLRQAGPRP--DEGGDPEPAL 82

                        90       100       110       120
                ....*....|....*....|....*....|....*....|.
gi 15598294  81 lsEGENDQIVEFTRGGWRNPLgqaRSRLQRVRWSLSGETLE 121
Cdd:COG4795  83 --SGGGSCLIDLNRNGWWNPL---RSELQRVGYRLRDGALE 118
PilW COG4966
Type IV pilus assembly protein PilW [Cell motility, Extracellular structures];
1-75 3.93e-11

Type IV pilus assembly protein PilW [Cell motility, Extracellular structures];


Pssm-ID: 443992 [Multi-domain]  Cd Length: 158  Bit Score: 59.42  E-value: 3.93e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598294   1 MRLQRGFTLLELLIAIAIFALLALATYRMFDSVMQT----DQATRVQEQ-RMrelvrAMGALERDLTQAVERPVRDELGD 75
Cdd:COG4966   1 RRRQRGFTLVELMVALAIGLIVLAAVLQLFLSSRRSyrtqEALARLQENgRF-----ALDLLSRDLRQAGYFGCASGNGN 75
PulG COG2165
Type II secretory pathway, pseudopilin PulG [Cell motility, Intracellular trafficking, ...
 1-60 1.54e-10

Type II secretory pathway, pseudopilin PulG [Cell motility, Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 441768 [Multi-domain]  Cd Length: 99  Bit Score: 56.46  E-value: 1.54e-10
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598294   1 MRLQRGFTLLELLIAIAIFALLALATYRMFDSVMQTDQATRVQEQrMRELVRAMGALERD 60
Cdd:COG2165   7 RRRQRGFTLIELLVVIAIIGILAALALPALQGARERARRAELRSN-LRQIQQALERYRLD 65
N_methyl pfam07963
Prokaryotic N-terminal methylation motif; This short motif directs methylation of the ...
 1-27 9.69e-09

Prokaryotic N-terminal methylation motif; This short motif directs methylation of the conserved phenylalanine residue. It is most often found at the N-terminus of pilins and other proteins involved in secretion, see pfam00114, pfam05946, pfam02501 and pfam07596.


Pssm-ID: 429756 [Multi-domain]  Cd Length: 27  Bit Score: 49.68  E-value: 9.69e-09
                          10        20
                  ....*....|....*....|....*..
gi 15598294     1 MRLQRGFTLLELLIAIAIFALLALATY 27
Cdd:pfam07963   1 MRKQRGFTLIELLVALAILAILLAAAL 27
PilV COG4967
Type IV pilus assembly protein PilV [Cell motility, Extracellular structures];
1-54 3.82e-08

Type IV pilus assembly protein PilV [Cell motility, Extracellular structures];


Pssm-ID: 443993 [Multi-domain]  Cd Length: 86  Bit Score: 49.60  E-value: 3.82e-08
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15598294   1 MRLQRGFTLLELLIAIAIFA--LLALATY-----RMFDSVMQTDQATRVQEQRMrELVRAM 54
Cdd:COG4967   7 RRRQRGFTLIEVLVALVILSigLLGLAGLqaaslRSSQDARQRTQAALLAQDLL-ERLRAN 66
PilE COG4968
Type IV pilus assembly protein PilE [Cell motility, Extracellular structures];
1-63 5.92e-08

Type IV pilus assembly protein PilE [Cell motility, Extracellular structures];


Pssm-ID: 443994 [Multi-domain]  Cd Length: 124  Bit Score: 50.07  E-value: 5.92e-08
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15598294   1 MRLQRGFTLLELLIAIAIFALLALATYRMFdsvmqTDQATRVQEQRMR-ELVRAMGALERDLTQ 63
Cdd:COG4968   6 RRRQRGFTLIELMIVVAIIGILAAIAIPSY-----QDYVERARRAEAKaALLELAQAQERYYAD 64
IV_pilin_GFxxxE TIGR02532
prepilin-type N-terminal cleavage/methylation domain; This model describes many but not all ...
 4-27 2.44e-07

prepilin-type N-terminal cleavage/methylation domain; This model describes many but not all examples of the N-terminal region of bacterial proteins that resemble type IV pilins at their N-terminus, with a cleavage site G^FxxxE followed by a hydrophobic stretch. The new N-terminal residue, usually Phe, is methylated. Separate domains of the prepilin peptidase appear responsible for cleavage and methylation. Proteins with this N-terminal region include type IV pilins and other components of pilus biogenesis, competence proteins, and type II secretion proteins. Typically several proteins in a single operon have this N-terminal domain. The N-terminal cleavage and methylation site is described by PROSITE motif PS00409 as [KRHEQSTAG]-G-[FYLIVM]-[ST]-[LT]-[LIVP]-E-[LIVMFWSTAG](14). [Cell envelope, Surface structures, Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274182 [Multi-domain]  Cd Length: 24  Bit Score: 45.76  E-value: 2.44e-07
                          10        20
                  ....*....|....*....|....
gi 15598294     4 QRGFTLLELLIAIAIFALLALATY 27
Cdd:TIGR02532   1 QRGFTLIELLVVLAILGILALIAL 24
FimT COG4970
Type IV pilus assembly protein FimT [Cell motility, Extracellular structures];
1-45 5.02e-07

Type IV pilus assembly protein FimT [Cell motility, Extracellular structures];


Pssm-ID: 443996 [Multi-domain]  Cd Length: 73  Bit Score: 45.99  E-value: 5.02e-07
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*
gi 15598294   1 MRLQRGFTLLELLIAIAIFALLALATYRMFDSVMQTDQATRVQEQ 45
Cdd:COG4970   5 RRRQRGFTLIELLVVLAILAILAAIAVPSFSSLIARQRLRAAANE 49
gspI TIGR01707
type II secretion system protein I; This model represents GspI, one of two proteins highly ...
 6-85 2.46e-06

type II secretion system protein I; This model represents GspI, one of two proteins highly conserved at their N-termini and described by pfam02501 but easily separable phylogenetically. The other is GspJ. Both GspI and GspJ are proteins of the type II secretion pathway, or main terminal branch of the general secretion pathway. This pathway carries proteins across the outer membrane. Note that proteins of type II secretion are cryptic in E. coli K-12 - present but not yet demonstrated to act on any target.


Pssm-ID: 273767 [Multi-domain]  Cd Length: 101  Bit Score: 44.82  E-value: 2.46e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598294     6 GFTLLELLIAIAIFALLALatyrmfdSVMQTDQATRVQEQRMRELVRAMGALERDLTQAVERPVRDELGDNRGAFLSEGE 85
Cdd:TIGR01707   1 GFTLLEVLVALAIFAAAAL-------ALISSVGGQTNAIGRLRDKTLALWIADNRLAELSLGVGPPALGRNSGKELIAGR 73
PilA COG4969
Type IV pilus assembly protein, major pilin PilA [Cell motility, Extracellular structures];
1-23 2.70e-05

Type IV pilus assembly protein, major pilin PilA [Cell motility, Extracellular structures];


Pssm-ID: 443995 [Multi-domain]  Cd Length: 134  Bit Score: 42.77  E-value: 2.70e-05
                        10        20
                ....*....|....*....|....
gi 15598294   1 MRL-QRGFTLLELLIAIAIFALLA 23
Cdd:COG4969   1 MKKkQKGFTLIELMIVVAIIGILA 24
PRK10557 PRK10557
prepilin peptidase-dependent protein;
4-64 1.88e-04

prepilin peptidase-dependent protein;


Pssm-ID: 236714  Cd Length: 192  Bit Score: 41.12  E-value: 1.88e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15598294    4 QRGFTLLELLIAIAIFALLALATYRMF----DSVMQTDQATRVQEqrmrELVRAMGALERDLTQA 64
Cdd:PRK10557   6 QRGFSLLEVLLAMAIGSVLLLGAARFLpalqRQILTLTRQLRLED----EIWQRVFTVEKDLRRA 66
PRK10574 PRK10574
putative major pilin subunit; Provisional
 1-22 2.39e-04

putative major pilin subunit; Provisional


Pssm-ID: 236718 [Multi-domain]  Cd Length: 146  Bit Score: 40.02  E-value: 2.39e-04
                         10        20
                 ....*....|....*....|..
gi 15598294    1 MRLQRGFTLLELLIAIAIFALL 22
Cdd:PRK10574   1 MDKQRGFTLIELMVVIAIIAIL 22
ComGC COG4537
Competence protein ComGC [Mobilome: prophages, transposons];
1-24 8.94e-04

Competence protein ComGC [Mobilome: prophages, transposons];


Pssm-ID: 443603 [Multi-domain]  Cd Length: 108  Bit Score: 37.60  E-value: 8.94e-04
                        10        20
                ....*....|....*....|....
gi 15598294   1 MRLQRGFTLLELLIAIAIFALLAL 24
Cdd:COG4537   8 LKKEKGFTLIEMLIVLLIISILLL 31
T4P_ComGE NF041013
competence type IV pilus minor pilin ComGE;
5-85 1.34e-03

competence type IV pilus minor pilin ComGE;


Pssm-ID: 468942 [Multi-domain]  Cd Length: 83  Bit Score: 36.79  E-value: 1.34e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598294    5 RGFTLLELLIAIAIFALLALATYRMFDSVMQTDQATRVQEQRMRELVRAMGALERDLTQAvERPVRDELGDNRGAFLSEG 84
Cdd:NF041013   4 KGFILLESLVALALLALIVSLLLPSLTQIQKEREEIKQKEEALQVLYEALQTYQLHLELN-GVEITVERSNTQIKVYWEG 82


                 .
gi 15598294   85 E 85
Cdd:NF041013  83 K 83
PRK10506 PRK10506
prepilin peptidase-dependent protein;
1-24 2.00e-03

prepilin peptidase-dependent protein;


Pssm-ID: 236704 [Multi-domain]  Cd Length: 162  Bit Score: 37.67  E-value: 2.00e-03
                         10        20
                 ....*....|....*....|....
gi 15598294    1 MRLQRGFTLLELLIAIAIFALLAL 24
Cdd:PRK10506   5 MKKQRGYTLIELLVVMTIVSILSA 28
pilin_ComGF NF041002
competence type IV pilus minor pilin ComGF; ComGF is one of several minor pilins in the type ...
 4-86 2.52e-03

competence type IV pilus minor pilin ComGF; ComGF is one of several minor pilins in the type IV pilus involved in the competence system of natural transformation by various Gram-positive bacteria. Oddly, while nearly all members have an N-terminal region with a consensus site for cleavage and methylation, ComGF from Bacillus subtilis appears N-terminally truncated, and may be functional despite the truncation.


Pssm-ID: 468931 [Multi-domain]  Cd Length: 138  Bit Score: 37.21  E-value: 2.52e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598294    4 QRGFTLLELLIAIAIFALLALATYRMFDSVMQTDQATRVQEQrmRELVRAMGALERDLTQAVERPVRDELGDNRGAFLSE 83
Cdd:NF041002   1 EKGFTLLECLVALLVLSLILLLIPLLIKLLLKVEQYLNNSDQ--LEWLLFLQQLESELKESTFKVKNNKLYVKLDLIKSN 78


                 ...
gi 15598294   84 GEN 86
Cdd:NF041002  79 GKT 81
TIGR02596 TIGR02596
Verru_Chthon cassette protein D; This model describes a nearly twenty member protein family in ...
 7-69 6.62e-03

Verru_Chthon cassette protein D; This model describes a nearly twenty member protein family in Verrucomicrobium spinosum and a somewhat smaller paralogous family in Chthoniobacter flavus. All members share a type IV pilin-like N-terminal leader sequence (TIGR02532). These proteins occur in the four-gene Verru_Chthon cassette, in which two other genes likewise encode a cleavage/methylation domain. Most of these cassettes occur next to an unusually large PEP-CTERM protein with an autotransporter domain. [Cell envelope, Surface structures]


Pssm-ID: 274219 [Multi-domain]  Cd Length: 195  Bit Score: 36.68  E-value: 6.62e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15598294     7 FTLLELLIAIAIFALL-ALATYrMFDSVMQTDQATRVQEQRMRELvramgALERDLTQAVERPV 69
Cdd:TIGR02596   1 FTLVELLVVIAIAALLmALSTP-VVNQVLAAQQLGSSATRLANEL-----AAAAQLAVRENRPV 58
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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