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Conserved domains on  [gi|15598753|ref|NP_252247|]
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4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE [Pseudomonas aeruginosa PAO1]

Protein Classification

DMT family transporter( domain architecture ID 581036)

DMT (drug/metabolite transporter) family transporter is an inner membrane protein involved in the transport of one or more of a variety of substrates such as amino acids, drugs, metabolites, and sugar phosphates, among others

Gene Ontology:  GO:0055085|GO:0005215|GO:0005886
PubMed:  11432728
TCDB:  2.A.7

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
EamA super family cl23754
EamA-like transporter family; This family includes many hypothetical membrane proteins of ...
 63-115 3.78e-11

EamA-like transporter family; This family includes many hypothetical membrane proteins of unknown function. Many of the proteins contain two copies of the aligned region. The family used to be known as DUF6. Members of this family usually carry 5+5 transmembrane domains, and this domain attempts to model five of these.


The actual alignment was detected with superfamily member PRK15051:

Pssm-ID: 474045  Cd Length: 111  Bit Score: 55.59  E-value: 3.78e-11
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 15598753   63 QRVEVGSAYPMLALNFVLVTLAARFVFDEPVDRRHLAGLLLIVAGVALLGRSA 115
Cdd:PRK15051  59 QNVPVGIAYPMLSLNFVWVTLAAVKLWHEPVSPRHWCGVAFIIGGIVILGSTV 111
 
Name Accession Description Interval E-value
PRK15051 PRK15051
4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional
 63-115 3.78e-11

4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional


Pssm-ID: 185011  Cd Length: 111  Bit Score: 55.59  E-value: 3.78e-11
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 15598753   63 QRVEVGSAYPMLALNFVLVTLAARFVFDEPVDRRHLAGLLLIVAGVALLGRSA 115
Cdd:PRK15051  59 QNVPVGIAYPMLSLNFVWVTLAAVKLWHEPVSPRHWCGVAFIIGGIVILGSTV 111
EmrE COG2076
Multidrug transporter EmrE and related cation transporters [Defense mechanisms];
63-111 3.19e-06

Multidrug transporter EmrE and related cation transporters [Defense mechanisms];


Pssm-ID: 441679  Cd Length: 105  Bit Score: 42.39  E-value: 3.19e-06
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|
gi 15598753  63 QRVEVGSAYPML-ALNFVLVTLAARFVFDEPVDRRHLAGLLLIVAGVALL 111
Cdd:COG2076  50 KTLPVGTAYAVWtGIGAVGTALVGILLFGEPLSLARLLGIALIIAGVVGL 99
 
Name Accession Description Interval E-value
PRK15051 PRK15051
4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional
 63-115 3.78e-11

4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional


Pssm-ID: 185011  Cd Length: 111  Bit Score: 55.59  E-value: 3.78e-11
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 15598753   63 QRVEVGSAYPMLALNFVLVTLAARFVFDEPVDRRHLAGLLLIVAGVALLGRSA 115
Cdd:PRK15051  59 QNVPVGIAYPMLSLNFVWVTLAAVKLWHEPVSPRHWCGVAFIIGGIVILGSTV 111
EmrE COG2076
Multidrug transporter EmrE and related cation transporters [Defense mechanisms];
63-111 3.19e-06

Multidrug transporter EmrE and related cation transporters [Defense mechanisms];


Pssm-ID: 441679  Cd Length: 105  Bit Score: 42.39  E-value: 3.19e-06
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|
gi 15598753  63 QRVEVGSAYPML-ALNFVLVTLAARFVFDEPVDRRHLAGLLLIVAGVALL 111
Cdd:COG2076  50 KTLPVGTAYAVWtGIGAVGTALVGILLFGEPLSLARLLGIALIIAGVVGL 99
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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