|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10246 |
PRK10246 |
exonuclease subunit SbcC; Provisional |
1-1199 |
8.35e-101 |
|
exonuclease subunit SbcC; Provisional
Pssm-ID: 182330 [Multi-domain] Cd Length: 1047 Bit Score: 344.48 E-value: 8.35e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 1 MKILAIRLKNLASLAGEQEIDFTREPLSSAGLFAITGPTGAGKSTVLDALCLALFGSTPRLESTSASskvpdgrnelssn 80
Cdd:PRK10246 1 MKILSLRLKNLNSLKGEWKIDFTAEPFASNGLFAITGPTGAGKTTLLDAICLALYHETPRLNNVSQS------------- 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 81 dERNLLRRGCASGYAEVDFvGIDGHRYRARWETRRSRDKADGALQKSQQSLQDLETQQMLaANKKSEFREQLEQKLGLNF 160
Cdd:PRK10246 68 -QNDLMTRDTAECLAEVEF-EVKGEAYRAFWSQNRARNQPDGNLQAPRVELARCADGKIL-ADKVKDKLELTATLTGLDY 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 161 AQFTRAVLLAQSEFSAFLKASDNDRGALLEKLTDTGLYSQLSKAAYQRASQADEQRKQLEQRLEGSLPLAEQARAGLEAA 240
Cdd:PRK10246 145 GRFTRSMLLSQGQFAAFLNAKPKERAELLEELTGTEIYGQISAMVFEQHKSARTELEKLQAQASGVALLTPEQVQSLTAS 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 241 LESHAQARLQEQQALQRLEGQQQWFTEEQRLLQSCEHAQGQLAEARQAWDALATERETLQWLERLAPVRGLIERLKQLEQ 320
Cdd:PRK10246 225 LQVLTDEEKQLLTAQQQQQQSLNWLTRLDELQQEASRRQQALQQALAAEEKAQPQLAALSLAQPARQLRPHWERIQEQSA 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 321 ELRHSEqqqrqrteqqaagtERLQGLQARLQEARERQAqadnhlRQAQAPLREAFQLESEARRLERTLAERqelhrqsnq 400
Cdd:PRK10246 305 ALAHTR--------------QQIEEVNTRLQSTMALRA------RIRHHAAKQSAELQAQQQSLNTWLAEH--------- 355
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 401 rhaqqsDAARQLDMEQQRHVAEQAQLQaalRDSQALAALgdawvthQGQLATFVQRRqralesqAQLPELEKSLAhagep 480
Cdd:PRK10246 356 ------DRFRQWNNELAGWRAQFSQQT---SDREQLRQW-------QQQLTHAEQKL-------NALPAITLTLT----- 407
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 481 lerlqaqwtalhgsePDDLAARLVELRRQTDSLERQQALHKEWQQVLDQRAGLARRLGELDQRMVEQEQAlLDLKRQgsq 560
Cdd:PRK10246 408 ---------------ADEVAAALAQHAEQRPLRQRLVALHGQIVPQQKRLAQLQVAIQNVTQEQTQRNAA-LNEMRQ--- 468
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 561 caeEVKAAEQALQVTRELLQRQrlARSASVEQLRAGLVDGEACPVCGSQEHPYHHSEQLLaalgEHDDQEQVRAEqsLER 640
Cdd:PRK10246 469 ---RYKEKTQQLADVKTICEQE--ARIKDLEAQRAQLQAGQPCPLCGSTSHPAVEAYQAL----EPGVNQSRLDA--LEK 537
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 641 LRQTLvglregyssqrerlnqsRQEQQELTGQLAALDRQLDQWTlPEELRLLQPSAQLEWLAQRLDDLAGQRQQCQRDFD 720
Cdd:PRK10246 538 EVKKL-----------------GEEGAALRGQLDALTKQLQRDE-SEAQSLRQEEQALTQQWQAVCASLNITLQPQDDIQ 599
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 721 RLIARQrqtqqlqqelraaetilQQRQQALTEQRQRYEhLQQQVEEDSQQLRPLlsDEHWQRWQADPLRTFQALGESieq 800
Cdd:PRK10246 600 PWLDAQ-----------------EEHERQLRLLSQRHE-LQGQIAAHNQQIIQY--QQQIEQRQQQLLTALAGYALT--- 656
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 801 rrqqqarlqqieqrlqeLKQRCDESSWQlkqsDEQRNEARQAEERaQAELAELNGRLGAhlgqhacaqdWQLSLEHAAQA 880
Cdd:PRK10246 657 -----------------LPQEDEEASWL----ATRQQEAQSWQQR-QNELTALQNRIQQ----------LTPLLETLPQS 704
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 881 AQSAVETLQAPLDSLRE---EQLRLAEALEHLQQQRQRQQDEFQRLQADWQAWRERQDNLDDSRLDALLgLSEEQATQWR 957
Cdd:PRK10246 705 DDLPHSEETVALDNWRQvheQCLSLHSQLQTLQQQDVLEAQRLQKAQAQFDTALQASVFDDQQAFLAAL-LDEETLTQLE 783
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 958 EQLQRLQEEITRQQTLEAERQAQLLQHRRQRPE-----TDREALEDNLRQQRERLAASEQAYLETYSQLQADNQRREQSQ 1032
Cdd:PRK10246 784 QLKQNLENQRQQAQTLVTQTAQALAQHQQHRPDgldltVTVEQIQQELAQLAQQLRENTTRQGEIRQQLKQDADNRQQQQ 863
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 1033 ALLAELERARAEFRRWGRLNELIGSSSGDKFRRIAQGYNLDLLVQHSNVQLRQLARRYRLQRGGSE-LGLLVVDTEMGDE 1111
Cdd:PRK10246 864 ALMQQIAQATQQVEDWGYLNSLIGSKEGDKFRKFAQGLTLDNLVWLANQQLTRLHGRYLLQRKASEaLELEVVDTWQADA 943
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 1112 LRSVYSLSGGETFLISLALALGLASMASSKLRIESLFIDEGFGSLDPESLQLAMDALDNLQAQGRKVAVISHVQEMHERI 1191
Cdd:PRK10246 944 VRDTRTLSGGESFLVSLALALALSDLVSHKTRIDSLFLDEGFGTLDSETLDTALDALDALNASGKTIGVISHVEAMKERI 1023
|
....*...
gi 15599478 1192 PVQVRVQR 1199
Cdd:PRK10246 1024 PVQIKVKK 1031
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
1-1203 |
3.18e-59 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 222.15 E-value: 3.18e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 1 MKILAIRLKNLASLAGEQEIDFTREPlssaGLFAITGPTGAGKSTVLDALCLALFGSTPRLESTSASskvpdgrnelssn 80
Cdd:TIGR00618 1 MKPLRLTLKNFGSYKGTHTIDFTALG----PIFLICGKTGAGKTTLLDAITYALYGKLPRRSEVIRS------------- 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 81 dERNLLRRGCASGYAEVDFVgIDGHRYRARWETRRSRDKADGALQKSQQSLQDlETQQMLAANKKSEFREQLEQKLGLNF 160
Cdd:TIGR00618 64 -LNSLYAAPSEAAFAELEFS-LGTKIYRVHRTLRCTRSHRKTEQPEQLYLEQK-KGRGRILAAKKSETEEVIHDLLKLDY 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 161 AQFTRAVLLAQSEFSAFLKASDNDRGALLEKLTDTGLYSQLSKAAYQRASQADEQRKQLEQRLEGSLPLAEQARAGLEAA 240
Cdd:TIGR00618 141 KTFTRVVLLPQGEFAQFLKAKSKEKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHER 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 241 LESHAQARLQEQQALQRLEGQQQWFTEEQRLLQscehaqgqlaearqawdalaterETLQWLERLAPVRGLIERLKQLEQ 320
Cdd:TIGR00618 221 KQVLEKELKHLREALQQTQQSHAYLTQKREAQE-----------------------EQLKKQQLLKQLRARIEELRAQEA 277
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 321 ELrhseqqqrqrteqqaagterlqglqARLQEARERQAQADNHLRQAQAPLREAFQLESEARRLERTLAERQELHRQSNQ 400
Cdd:TIGR00618 278 VL-------------------------EETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAA 332
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 401 RHAQQSDAARQLDMEQQRHVAEQAQLQAAlrDSQALaalgdaWVTHQGQLATFVQRRQRALESQAQLPELEKSLAHAGEP 480
Cdd:TIGR00618 333 HVKQQSSIEEQRRLLQTLHSQEIHIRDAH--EVATS------IREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDI 404
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 481 LERLQAQWTALHGSEPDdlaarlvelrrqtdslERQQALHKEWQQVLDQRaglarRLGELDQRMVEQEQALLDLKRQGSQ 560
Cdd:TIGR00618 405 LQREQATIDTRTSAFRD----------------LQGQLAHAKKQQELQQR-----YAELCAAAITCTAQCEKLEKIHLQE 463
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 561 CAEEVKAAEQALQVTRELLQRQrlARSASVEQLRAGLVDGEACPVCGSQEHPYHHSEQL-----LAALGEHDDQEQVRAE 635
Cdd:TIGR00618 464 SAQSLKEREQQLQTKEQIHLQE--TRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIdnpgpLTRRMQRGEQTYAQLE 541
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 636 QSLERLRQTLVGLREGYSSQRERLNQSRQEQQELTGQLAALDRQLDQWTLPEELrlLQPSAQLEWLAQRLDDLAGQRQQC 715
Cdd:TIGR00618 542 TSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVR--LQDLTEKLSEAEDMLACEQHALLR 619
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 716 QrdfdrliarQRQTQQLQQELRAAETILQQRQQALTEQRQRYEHLQQQVEEDSQQLRPLLSDEHWQRWQADPlrtfQALG 795
Cdd:TIGR00618 620 K---------LQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLAL----QKMQ 686
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 796 ESIEQRRQQQARLQQIEQRLQELKQRcdesswqLKQSDEQRNEARQAEERAQAELAELNGRLGAHLGQHACAQDWQLSle 875
Cdd:TIGR00618 687 SEKEQLTYWKEMLAQCQTLLRELETH-------IEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLK-- 757
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 876 haAQAAQSAVETLQAPLDSLREEQLrlaealehlqqqrqrqqdefqrlqadwqawrerqdnlddsrldallglseEQATQ 955
Cdd:TIGR00618 758 --ARTEAHFNNNEEVTAALQTGAEL--------------------------------------------------SHLAA 785
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 956 WREQLQRLQEEITRQQTLEAERQAQLLQHRRQRPETDREALEDNLRQQRERLAASEQAYLETYSQLQADNQRREQSQALL 1035
Cdd:TIGR00618 786 EIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLT 865
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 1036 AELERARAEFRRWGRLNELIGSSSGDKFRRIAQGYNLDLLVQHSNVQLRQLARRYRLQR---GGSELGLLVVDTEMGDEL 1112
Cdd:TIGR00618 866 QEQAKIIQLSDKLNGINQIKIQFDGDALIKFLHEITLYANVRLANQSEGRFHGRYADSHvnaRKYQGLALLVADAYTGSV 945
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 1113 RSVYSLSGGETFLISLALALGLASMAS--SKLRIESLFIDEGFGSLDPESLQLAMDALDNLQAQGRKVAVISHVQEMHER 1190
Cdd:TIGR00618 946 RPSATLSGGETFLASLSLALALADLLStsGGTVLDSLFIDEGFGSLDEDSLDRAIGILDAIREGSKMIGIISHVPEFRER 1025
|
1210
....*....|...
gi 15599478 1191 IPVQVRVQREGNG 1203
Cdd:TIGR00618 1026 IPHRILVKKTNAG 1038
|
|
| ABC_sbcCD |
cd03279 |
ATP-binding cassette domain of sbcCD; SbcCD and other Mre11/Rad50 (MR) complexes are ... |
1113-1203 |
7.76e-32 |
|
ATP-binding cassette domain of sbcCD; SbcCD and other Mre11/Rad50 (MR) complexes are implicated in the metabolism of DNA ends. They cleave ends sealed by hairpin structures and are thought to play a role in removing protein bound to DNA termini.
Pssm-ID: 213246 [Multi-domain] Cd Length: 213 Bit Score: 123.92 E-value: 7.76e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 1113 RSVYSLSGGETFLISLALALGLASMASSKL--RIESLFIDEGFGSLDPESLQLAMDALDNLQAQGRKVAVISHVQEMHER 1190
Cdd:cd03279 119 RPVSTLSGGETFLASLSLALALSEVLQNRGgaRLEALFIDEGFGTLDPEALEAVATALELIRTENRMVGVISHVEELKER 198
|
90
....*....|...
gi 15599478 1191 IPVQVRVQREGNG 1203
Cdd:cd03279 199 IPQRLEVIKTPGG 211
|
|
| AAA_23 |
pfam13476 |
AAA domain; |
6-222 |
2.11e-26 |
|
AAA domain;
Pssm-ID: 463890 [Multi-domain] Cd Length: 190 Bit Score: 107.58 E-value: 2.11e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 6 IRLKNLASLaGEQEIDFtreplsSAGLFAITGPTGAGKSTVLDALCLALFGSTPRLestsasskvPDGRNELSSNDERNL 85
Cdd:pfam13476 1 LTIENFRSF-RDQTIDF------SKGLTLITGPNGSGKTTILDAIKLALYGKTSRL---------KRKSGGGFVKGDIRI 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 86 LRRGCASGYAEVDFVGIDGHR-YRARWETRRSRDKADGALQKSQQSLQDLETQQMlaankksefreqLEQKLGLNFAQFT 164
Cdd:pfam13476 65 GLEGKGKAYVEITFENNDGRYtYAIERSRELSKKKGKTKKKEILEILEIDELQQF------------ISELLKSDKIILP 132
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 15599478 165 RAVLLAQSEFSAFLKASDNDRGALLEKLTDTGLYSQLSKAAYQRASQADEQRKQLEQR 222
Cdd:pfam13476 133 LLVFLGQEREEEFERKEKKERLEELEKALEEKEDEKKLLEKLLQLKEKKKELEELKEE 190
|
|
| ABC_sbcCD |
cd03279 |
ATP-binding cassette domain of sbcCD; SbcCD and other Mre11/Rad50 (MR) complexes are ... |
1-179 |
1.23e-23 |
|
ATP-binding cassette domain of sbcCD; SbcCD and other Mre11/Rad50 (MR) complexes are implicated in the metabolism of DNA ends. They cleave ends sealed by hairpin structures and are thought to play a role in removing protein bound to DNA termini.
Pssm-ID: 213246 [Multi-domain] Cd Length: 213 Bit Score: 100.42 E-value: 1.23e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 1 MKILAIRLKNLASLAGEQEIDFTrePLSSAGLFAITGPTGAGKSTVLDALCLALFGSTPRLEstsasskvpdgrnelSSN 80
Cdd:cd03279 1 MKPLKLELKNFGPFREEQVIDFT--GLDNNGLFLICGPTGAGKSTILDAITYALYGKTPRYG---------------RQE 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 81 DERNLLRRGCASgyAEVDFV-GIDGHRYRArwetrrsrdkadgalqksqqslqdletqqmlaankksefreqlEQKLGLN 159
Cdd:cd03279 64 NLRSVFAPGEDT--AEVSFTfQLGGKKYRV-------------------------------------------ERSRGLD 98
|
170 180
....*....|....*....|
gi 15599478 160 FAQFTRAVLLAQSEFSAFLK 179
Cdd:cd03279 99 YDQFTRIVLLPQGEFDRFLA 118
|
|
| SbcC |
COG0419 |
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]; |
2-221 |
5.80e-20 |
|
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];
Pssm-ID: 440188 [Multi-domain] Cd Length: 204 Bit Score: 89.30 E-value: 5.80e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 2 KILAIRLKNLASLAGEQEIDFTReplssaGLFAITGPTGAGKSTVLDALCLALFGSTPRlestsasskvpdgrnelSSND 81
Cdd:COG0419 1 KLLRLRLENFRSYRDTETIDFDD------GLNLIVGPNGAGKSTILEAIRYALYGKARS-----------------RSKL 57
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 82 ERNLLRRGCASGYAEVDFVgIDGHRYRARWetrrsrdkadgalqksqqslqdletqqmlaankksefreqleqklglnfa 161
Cdd:COG0419 58 RSDLINVGSEEASVELEFE-HGGKRYRIER-------------------------------------------------- 86
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 162 qftravllAQSEFSAFLKASDNDRGALLEKLTDTGLYSQLSKAAYQRASQADEQRKQLEQ 221
Cdd:COG0419 87 --------RQGEFAEFLEAKPSERKEALKRLLGLEIYEELKERLKELEEALESALEELAE 138
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
311-1054 |
8.02e-17 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 86.26 E-value: 8.02e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 311 LIERLKQLEQELRHSEQQQRQRTEQQAAGTERLQGLQARLQEARERQAQADNHLRQAQAPLREAFQLESEA-RRLERTLA 389
Cdd:TIGR02168 230 LVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLeQQKQILRE 309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 390 ERQELHRQSNQRHAQQSDAARQLDMEQQRHVAEQAQLQAALRDSQALAALGDAWVthqgqlATFVQRRQRALESQAQLPE 469
Cdd:TIGR02168 310 RLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELE------AELEELESRLEELEEQLET 383
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 470 LEKSLAHAGEPLERLQAQWTALhGSEPDDLAARLVELRRQTDSLERQQALHkewqqvldQRAGLARRLGELDQRMVEQEQ 549
Cdd:TIGR02168 384 LRSKVAQLELQIASLNNEIERL-EARLERLEDRRERLQQEIEELLKKLEEA--------ELKELQAELEELEEELEELQE 454
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 550 ALLDLKRQGSQCAEEVKAAEQALQVTRELLQR--QRLARSASVEQLRAGLVDGEACPVCGSQEHPYHH---SEQ------ 618
Cdd:TIGR02168 455 ELERLEEALEELREELEEAEQALDAAERELAQlqARLDSLERLQENLEGFSEGVKALLKNQSGLSGILgvlSELisvdeg 534
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 619 ----LLAALGEH-------DDQEQVRAEQSLERLRQTLVGLREgYSSQRERLNQSRQEQQeLTGQLAALDRQLDQWTLPE 687
Cdd:TIGR02168 535 yeaaIEAALGGRlqavvveNLNAAKKAIAFLKQNELGRVTFLP-LDSIKGTEIQGNDREI-LKNIEGFLGVAKDLVKFDP 612
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 688 ELR-LLQPSAQLEWLAQRLDDLAGQRQQCQRDFdRLIARQRQTQQLQ-----QELRAAETILQQRQ------QALTEQRQ 755
Cdd:TIGR02168 613 KLRkALSYLLGGVLVVDDLDNALELAKKLRPGY-RIVTLDGDLVRPGgvitgGSAKTNSSILERRReieeleEKIEELEE 691
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 756 RYEHLQQQVEEDSQQLRPLLSDEHWQRWQADPLRTFQALGEsiEQRRQQQARLQQIEQRLQELKQRCDESSWQLKQSDEQ 835
Cdd:TIGR02168 692 KIAELEKALAELRKELEELEEELEQLRKELEELSRQISALR--KDLARLEAEVEQLEERIAQLSKELTELEAEIEELEER 769
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 836 RNEARQAEERAQAELAELNGRLGAHLGQHacaqdwqlslehaaQAAQSAVETLQAPLDSLREEQLRLAEALEHLQQQRQR 915
Cdd:TIGR02168 770 LEEAEEELAEAEAEIEELEAQIEQLKEEL--------------KALREALDELRAELTLLNEEAANLRERLESLERRIAA 835
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 916 QQDEFQRLqadwqawrerqdnlddsrldallglsEEQATQWREQLQRLQEEITRQQTL--EAERQAQLLQHRRQRPETDR 993
Cdd:TIGR02168 836 TERRLEDL--------------------------EEQIEELSEDIESLAAEIEELEELieELESELEALLNERASLEEAL 889
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15599478 994 EALEDNLRQQRERLAASEQAYLETYSQLQADNQRREQSQALLAELERARAEFRrwGRLNEL 1054
Cdd:TIGR02168 890 ALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQ--ERLSEE 948
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
341-922 |
1.50e-15 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 81.91 E-value: 1.50e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 341 ERLQGLQARLQEAR-ERQAQADNHLRQAQAPLREAFQ-LESEARRLERTLAERQELHRQSNQRHAQQSDAARQLDMEQQR 418
Cdd:COG1196 213 ERYRELKEELKELEaELLLLKLRELEAELEELEAELEeLEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYE 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 419 HVAEQAQLQAALRDSQALAAlgDAWVTHQGQLATFVQRRQRALESQAQLPELEKSLAHAGEPLERLQAQWTALHGSEPDD 498
Cdd:COG1196 293 LLAELARLEQDIARLEERRR--ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 499 LAARLVELRRQTDSLERQQALHKEWQQVLDQRAGLARRLGELDQRMVEQEQALLDLKRQGSQCAEEVKAAEQALQVTREL 578
Cdd:COG1196 371 EAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEE 450
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 579 LQRQRLARSASVEQLRAGLvdgeacpvcgsqehpyhhSEQLLAALGEHDDQEQVRAEQSLERLRQTLVGLREGYSSQRER 658
Cdd:COG1196 451 EAELEEEEEALLELLAELL------------------EEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKA 512
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 659 LNQsRQEQQELTGQLAALDrqldqwTLPEELRLLQPSAQLEWLAQRLDDLAGQRQQCQRDFDRLIARQRQTQQLQQELRA 738
Cdd:COG1196 513 ALL-LAGLRGLAGAVAVLI------GVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRAR 585
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 739 AETILQQRQQALTEQRQRYEHLQQQVEEDSQQLRPLLSDEhwQRWQADPLRTFQALGESIEQRRQQQARLQQIEQRLQEL 818
Cdd:COG1196 586 AALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGR--TLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLT 663
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 819 KQRCDESSWQLKQSDEQRNEARQAEERAQAELAELNGRLGAHLGQHACAQDWQLSLEHAAQAAQSAVETLQAPLDSLREE 898
Cdd:COG1196 664 GGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLE 743
|
570 580
....*....|....*....|....
gi 15599478 899 QLRLAEALEHLQQQRQRQQDEFQR 922
Cdd:COG1196 744 EEELLEEEALEELPEPPDLEELER 767
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
216-818 |
2.99e-15 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 81.14 E-value: 2.99e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 216 RKQLEQRLEgslPLAEQARAGLEA-ALESHAQARLQEQQALQR--LEGQQQWFTEEQRLLQS-CEHAQGQLAEARQAWDA 291
Cdd:COG1196 195 LGELERQLE---PLERQAEKAERYrELKEELKELEAELLLLKLreLEAELEELEAELEELEAeLEELEAELAELEAELEE 271
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 292 LATERETLQWL--ERLAPVRGLIERLKQLEQELRHSEQQQRQRTEQQAAGTERLQGLQARLQEARERQAQADNHLRQAQA 369
Cdd:COG1196 272 LRLELEELELEleEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEE 351
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 370 PLREA-FQLESEARRLERTLAERQELHRQSNQRHAQQSDAARQLDMEQQRHVAEQAQLQAALRD--------SQALAALG 440
Cdd:COG1196 352 ELEEAeAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERlerleeelEELEEALA 431
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 441 DAWVTHQGQLATFVQRRQRALESQAQLPELEKSLAHAGEPLERLQAQWTALHGSEPDDLAARLVELRRQTDSLERQQALH 520
Cdd:COG1196 432 ELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVK 511
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 521 KewQQVLDQRAGLARRLGELDQRMVEQEQALLDlkRQGSQCAEEVKAAEQALQVTRELLQRQRLARSASVEQLRAGlvdg 600
Cdd:COG1196 512 A--ALLLAGLRGLAGAVAVLIGVEAAYEAALEA--ALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIR---- 583
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 601 eacpvcGSQEHPYHHSEQLLAALGEHDDQEQVRAEQSLERLRQTLVGLregySSQRERLNQSRQEQQELTGQLAALdrql 680
Cdd:COG1196 584 ------ARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGR----TLVAARLEAALRRAVTLAGRLREV---- 649
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 681 dqwTLPEELRLLQPSAQLEWLAQRLDDLAGQRQQCQRDFDRLIARQRQTQQLQQELRAAETILQQRQQALTEQRQRYEHL 760
Cdd:COG1196 650 ---TLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEAL 726
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*...
gi 15599478 761 QQQVEEDSQQLRPLLSDEhwqrwQADPLRTFQALGESIEQRRQQQARLQQIEQRLQEL 818
Cdd:COG1196 727 EEQLEAEREELLEELLEE-----EELLEEEALEELPEPPDLEELERELERLEREIEAL 779
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
135-722 |
4.70e-15 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 80.37 E-value: 4.70e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 135 ETQQMLAANKKSEFREQLEQKlglnfaqfTRAVLLAQSEFSAFLKASDNDRGALLEKLTDTGLYSQLSKAAYQRASQADE 214
Cdd:COG1196 224 ELEAELLLLKLRELEAELEEL--------EAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 215 QRKQLEQRLEgslPLAEQARAGLEAALESHAQARLQEQQALQRLEGQQQWFTEEQRLLQSCEHAQGQLAEARQAWDALAT 294
Cdd:COG1196 296 ELARLEQDIA---RLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEA 372
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 295 ERETLQwlerlapvrgliERLKQLEQELRHSEQQQRQRTEQQAAGTERLQGLQARLQEARERQAQADNHLRQAQAPLREA 374
Cdd:COG1196 373 ELAEAE------------EELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEE 440
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 375 FQLESEARRLERTLAERQELHRQSNQRHAQQSDAARQLDMEQQRHVAEQAQLQAALRDSQALAALGDAWVTHQGQLATFV 454
Cdd:COG1196 441 EEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLR 520
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 455 QRRQRALESQAQLPELEKSLAHAGEPLERLQAQWTALHGSEPDDLAARLVELRRQTDSLERQQALHKEWQQVLDQRAGLA 534
Cdd:COG1196 521 GLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAA 600
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 535 RRLGELDQRMVEQEQALLDLKRQGSqcAEEVKAAEQALQVTRELLQRQRLARSASVEQLRAGLVDGeacpvcgsqehpyh 614
Cdd:COG1196 601 VDLVASDLREADARYYVLGDTLLGR--TLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTG-------------- 664
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 615 HSEQLLAALGEHDDQEQVRAEQSLERLRQTLVGLREGYSSQRERLNQSRQEQQELTGQLAALDRQLDQWTLPEELRLLQP 694
Cdd:COG1196 665 GSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEE 744
|
570 580
....*....|....*....|....*...
gi 15599478 695 SAQLEWLAQRLDDLAGQRQQCQRDFDRL 722
Cdd:COG1196 745 EELLEEEALEELPEPPDLEELERELERL 772
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
214-1052 |
1.57e-14 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 78.95 E-value: 1.57e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 214 EQRKQLEqRLEGSLPLAEQARAgLEAALEsHAQARLQEQQALQRLEGQQQWFTEEQRLLQSCEHAQGQLAEARQAWDALA 293
Cdd:TIGR02168 197 ELERQLK-SLERQAEKAERYKE-LKAELR-ELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELR 273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 294 TERETLQwlERLAPVRGLIERLKQ----LEQELRHSEQQQRQRTEQQAAGTERLQGLQARLQEARERQAQADNHLRQAQA 369
Cdd:TIGR02168 274 LEVSELE--EEIEELQKELYALANeisrLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKE 351
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 370 plreafQLESEARRLERTLAERQELHRQSNQRHAQQSDAARQLDMEQQRHVAEQAQLQAALRDSQALAALGDAWVTHQGQ 449
Cdd:TIGR02168 352 ------ELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEE 425
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 450 LATFVQRRQRAlESQAQLPELEKSLAHAGEPLERLQAQWTALHGS------EPDDLAARLVELRRQTDSLERQQALH--- 520
Cdd:TIGR02168 426 LLKKLEEAELK-ELQAELEELEEELEELQEELERLEEALEELREEleeaeqALDAAERELAQLQARLDSLERLQENLegf 504
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 521 ----KEWQQVLDQRAGLARRLGELDQRMVEQEQALldlkrqgsqcaeEVKAAEQALQVTRELLQRQRLArSASVEQLRAG 596
Cdd:TIGR02168 505 segvKALLKNQSGLSGILGVLSELISVDEGYEAAI------------EAALGGRLQAVVVENLNAAKKA-IAFLKQNELG 571
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 597 LVDGEACPVCGSQEHPYHHSEQLLAALGEHDD-QEQVRAEQSLERLRQTLVGLREGYSSQRERLNQSRQEQQE-----LT 670
Cdd:TIGR02168 572 RVTFLPLDSIKGTEIQGNDREILKNIEGFLGVaKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGyrivtLD 651
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 671 GQLAALDRQLDQWTLPEELRLLQPSAQLEWLAQRLDDLAGQRQQCQRDFDRLIARQRQTQQLQQELRAAETILQQRQQAL 750
Cdd:TIGR02168 652 GDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISAL 731
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 751 TEQRQRYEHLQQQVEEDSQQLRPLLSDEHWQRWQADplrtfqalgesiEQRRQQQARLQQIEQRLQELKQRCDESSWQLK 830
Cdd:TIGR02168 732 RKDLARLEAEVEQLEERIAQLSKELTELEAEIEELE------------ERLEEAEEELAEAEAEIEELEAQIEQLKEELK 799
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 831 QSDEQRNEARQAEERAQAELAELNGRLGAHLGQHACAQDWQLSLEHAAQAAQSAVETLQAPLDSLREEQLRLAEALEHLQ 910
Cdd:TIGR02168 800 ALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALL 879
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 911 qqrqrqqDEFQRLQADWQAWRERQDNLDDSRLDAllglsEEQATQWREQLQRLQEEITRQQtleaerqaqllqhrrqrpe 990
Cdd:TIGR02168 880 -------NERASLEEALALLRSELEELSEELREL-----ESKRSELRRELEELREKLAQLE------------------- 928
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15599478 991 TDREALEDNLRQQRERLAASEQAYLETYSQLQadNQRREQSQALLAELERARAEFRRWGRLN 1052
Cdd:TIGR02168 929 LRLEGLEVRIDNLQERLSEEYSLTLEEAEALE--NKIEDDEEEARRRLKRLENKIKELGPVN 988
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
499-1047 |
7.89e-14 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 76.51 E-value: 7.89e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 499 LAARLVELRRQTDSLERQ-------QALHKEWQQVLDQRAGLARRLGELDQRMVEQEQALLDLKRqgsqcaEEVKAAEQA 571
Cdd:COG1196 191 LEDILGELERQLEPLERQaekaeryRELKEELKELEAELLLLKLRELEAELEELEAELEELEAEL------EELEAELAE 264
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 572 LQVTRELLQRQRLARSASVEQLRAGLvdgeacpvcgsqehpYHHSEQLLAALGE--HDDQEQVRAEQSLERLRQTLVGLR 649
Cdd:COG1196 265 LEAELEELRLELEELELELEEAQAEE---------------YELLAELARLEQDiaRLEERRRELEERLEELEEELAELE 329
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 650 EGYSSQRERLNQSRQEQQELTGQLAALDRQLDQWtlpEELRLLQPSAQLEWLAQRLDDLagqrqqcQRDFDRLIARQRQT 729
Cdd:COG1196 330 EELEELEEELEELEEELEEAEEELEEAEAELAEA---EEALLEAEAELAEAEEELEELA-------EELLEALRAAAELA 399
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 730 QQLQQELRAAETILQQRQQALTEQRQRYEHLQQQVEEDSQQLRPLLSDehwQRWQADPLRTFQALGESIEQRRQQQARLQ 809
Cdd:COG1196 400 AQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA---AEEEAELEEEEEALLELLAELLEEAALLE 476
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 810 QIEQRLQELKQRCDESSWQLKQSDEQRNEARQAEERAQ--------------------AELAELNGRLGAHLGQHACAQD 869
Cdd:COG1196 477 AALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALllaglrglagavavligveaAYEAALEAALAAALQNIVVEDD 556
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 870 WQLS--LEHAAQAAQSAVETLQAPLDSLREEQLRLAEALEHLQQQRQRQQDEfQRLQADWQAWRERQDNLDDSRLDALLG 947
Cdd:COG1196 557 EVAAaaIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDL-READARYYVLGDTLLGRTLVAARLEAA 635
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 948 LSEEQATQWREQLQRLQEEITRQQTLEAERQAQLLQHRRQRPETDREALEDNLRQQRERLAASEQAYLETYSQLQADNQR 1027
Cdd:COG1196 636 LRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEE 715
|
570 580
....*....|....*....|
gi 15599478 1028 REQSQALLAELERARAEFRR 1047
Cdd:COG1196 716 RLEEELEEEALEEQLEAERE 735
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
6-432 |
1.76e-13 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 74.67 E-value: 1.76e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 6 IRLKNLASLaGEQEIDFTrepLSSAGLFAITGPTGAGKSTVLDALCLALFGSTPRlestsaSSKVPDGRNelsSNDERNL 85
Cdd:PHA02562 7 IRYKNILSV-GNQPIEIQ---LDKVKKTLITGKNGAGKSTMLEALTFALFGKPFR------DIKKGQLIN---SINKKDL 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 86 LrrgcasgyAEVDFvGIDGHRYRArweTRRSRDK-----ADGALQKSQQSLQDletqqmlaankkseFREQLEQKLGLNF 160
Cdd:PHA02562 74 L--------VELWF-EYGEKEYYI---KRGIKPNvfeiyCNGKLLDESASSKD--------------FQKYFEQMLGMNY 127
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 161 AQFTRAVLLAQSEFSAFLKASDNDRGALLEKLTDTGLYSQLSK-------AAYQRASQADEQRKQLEQRL-------EGS 226
Cdd:PHA02562 128 KSFKQIVVLGTAGYVPFMQLSAPARRKLVEDLLDISVLSEMDKlnkdkirELNQQIQTLDMKIDHIQQQIktynkniEEQ 207
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 227 LPLAEQARAGLEAALESHAQARLQEQQALQRLEGQQQWFTEEQrllqscEHAQGQLAEARQAWDALATERETLQWLERLA 306
Cdd:PHA02562 208 RKKNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDI------EDPSAALNKLNTAAAKIKSKIEQFQKVIKMY 281
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 307 PVRGLIERLKQ-LEQElrhseqqqrqrteqqaagterlqglQARLQEARERQAQADNHLRQAQAPLREAFQLESEARRLE 385
Cdd:PHA02562 282 EKGGVCPTCTQqISEG-------------------------PDRITKIKDKLKELQHSLEKLDTAIDELEEIMDEFNEQS 336
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....
gi 15599478 386 RTLAERQ---ELHRQSNQRHAQQSDAAR----QLDMEQQRHVAEQAQLQAALRD 432
Cdd:PHA02562 337 KKLLELKnkiSTNKQSLITLVDKAKKVKaaieELQAEFVDNAEELAKLQDELDK 390
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
410-1007 |
9.52e-13 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 73.05 E-value: 9.52e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 410 RQLD-MEQQRHVAEQAQ-LQAALRDSQA-LAALGDAWVTHQGQL--ATFVQRRQRALESQAQLPELEKSLAHAGEPLERL 484
Cdd:COG1196 200 RQLEpLERQAEKAERYReLKEELKELEAeLLLLKLRELEAELEEleAELEELEAELEELEAELAELEAELEELRLELEEL 279
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 485 QAQWTALHGSEpDDLAARLVELRRQTDSL-ERQQALHKEWQQVLDQRAGLARRLGELDQRMVEQEQALLDLKRQGSQCAE 563
Cdd:COG1196 280 ELELEEAQAEE-YELLAELARLEQDIARLeERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEA 358
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 564 EVKAAEQALQ-VTRELLQRQRLARSASVEQLRAGlvdgeacpvcgsqehpyhHSEQLLAALGEHDDQEQVRAEQSLERLR 642
Cdd:COG1196 359 ELAEAEEALLeAEAELAEAEEELEELAEELLEAL------------------RAAAELAAQLEELEEAEEALLERLERLE 420
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 643 QTLVGLREGYSSQRERLNQSRQEQQELTGQLAALDRQLDQwtlpEELRLLQPSAQLEWLAQRLDDLAGQRQQCQRDFDRL 722
Cdd:COG1196 421 EELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEA----LLELLAELLEEAALLEAALAELLEELAEAAARLLLL 496
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 723 IARQRQTQQLQQELRAAETILQQRQQALTEQRqryehLQQQVEEDSQQLRPLLSDEHWQRWQADPLRTFQALGESIEQRR 802
Cdd:COG1196 497 LEAEADYEGFLEGVKAALLLAGLRGLAGAVAV-----LIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKA 571
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 803 QQQARLQQIEQRLQELKQRCDESSWQLKQSDEQRNEARQAEERAQAELAELNGRLGAHLGQHACAQDWQLSLEHAAQAAQ 882
Cdd:COG1196 572 GRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTL 651
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 883 SAVETLQAPLDSLREEQLRLAEALEHLQQQRQRQQDEFQRLQADWQAWRERQDNLDDSRLDALLGLSEEQATQWREQLQR 962
Cdd:COG1196 652 EGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLE 731
|
570 580 590 600
....*....|....*....|....*....|....*....|....*...
gi 15599478 963 LQEEITRQQTLEAERQAQLLQHRRQRPETDREALE---DNLRQQRERL 1007
Cdd:COG1196 732 AEREELLEELLEEEELLEEEALEELPEPPDLEELErelERLEREIEAL 779
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
267-782 |
3.82e-12 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 71.10 E-value: 3.82e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 267 EEQRLLQSCEHAQGQLAEARQAWDALATERETlqwLERLAPVRGLIERLKQLEQELRHSEQQQRQRTEQQAAgtERLQGL 346
Cdd:COG4913 219 EEPDTFEAADALVEHFDDLERAHEALEDAREQ---IELLEPIRELAERYAAARERLAELEYLRAALRLWFAQ--RRLELL 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 347 QARLQEARERQAQADNHLRQAQAPLREAFQLESEARR------------LERTLAERQELHRQSNQRHAQQSDAARQLDM 414
Cdd:COG4913 294 EAELEELRAELARLEAELERLEARLDALREELDELEAqirgnggdrleqLEREIERLERELEERERRRARLEALLAALGL 373
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 415 EQQRHVAEQAQLQAALRdsQALAALGDAWVTHQGQLATFVQRRQRALESQAQLPELEKSLAHAG----EPLERLQAQWTA 490
Cdd:COG4913 374 PLPASAEEFAALRAEAA--ALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKsnipARLLALRDALAE 451
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 491 LHGSEPDDL--AARLVELRrqtdslerqqALHKEWQQ--------------VLDQRAGLARRL-------GELD-QRMVE 546
Cdd:COG4913 452 ALGLDEAELpfVGELIEVR----------PEEERWRGaiervlggfaltllVPPEHYAAALRWvnrlhlrGRLVyERVRT 521
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 547 QEQALLDLKRQGSQCAEEVKAAEQALQ--VTRELLQRQRLARSASVEQLR--------AGLVdgeacpvcgsqehpyHHS 616
Cdd:COG4913 522 GLPDPERPRLDPDSLAGKLDFKPHPFRawLEAELGRRFDYVCVDSPEELRrhpraitrAGQV---------------KGN 586
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 617 eqllAALGEHDDQEQVR--------AEQSLERLRQTLVGLREGYSSQRERLNQSRQEQQELTGQLAALDR-------QLD 681
Cdd:COG4913 587 ----GTRHEKDDRRRIRsryvlgfdNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRlaeyswdEID 662
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 682 QWTLPEEL--------RLLQPSAQLEWLAQRLDDLAGQRQQCQRDFDRLIarqrqtqqlqqelrAAETILQQRQQALTEQ 753
Cdd:COG4913 663 VASAEREIaeleaeleRLDASSDDLAALEEQLEELEAELEELEEELDELK--------------GEIGRLEKELEQAEEE 728
|
570 580
....*....|....*....|....*....
gi 15599478 754 RQRYEHLQQQVEEDSQQLRPLLSDEHWQR 782
Cdd:COG4913 729 LDELQDRLEAAEDLARLELRALLEERFAA 757
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
635-1016 |
3.86e-12 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 71.12 E-value: 3.86e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 635 EQSLERLRQTlvglregyssqRERLNQSRQEQQELTGQLAALDRQLDQ----WTLPEELRLLQpsaqLEWLAQRLDDLAG 710
Cdd:COG1196 175 EEAERKLEAT-----------EENLERLEDILGELERQLEPLERQAEKaeryRELKEELKELE----AELLLLKLRELEA 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 711 QRQQcqrdfdrliaRQRQTQQLQQELRAAETILQQRQQALTEQRQRYEHLQQQVEEDSQQLRpllsdehwqrwqadplrt 790
Cdd:COG1196 240 ELEE----------LEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEY------------------ 291
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 791 fqalgESIEQRRQQQARLQQIEQRLQELKQRCDESSWQLKQSDEQRNEARQAEERAQAELAELNGRLGAHLGQHACAQDW 870
Cdd:COG1196 292 -----ELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEA 366
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 871 QLSLEHAAQAAQSAVETLQAPLDSLREEQLRLAEALEHLQQQRQRQQDEFQRLQADWQAWRERQDNLDDSRLDALLGLSE 950
Cdd:COG1196 367 LLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEE 446
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15599478 951 EQATQWREQLQRLQEEITRQQTLEAERQAQLLQHRRQRPETDREALEDNLRQQRERLAASEQAYLE 1016
Cdd:COG1196 447 AAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKA 512
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
101-969 |
4.06e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 67.77 E-value: 4.06e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 101 GIDGHRYRaRWETRRSRDKADGALQKSQQSLQDLETQ------QMLAANKKSEFREQLEQK----LGLNFAQFTRAVLLA 170
Cdd:TIGR02168 166 GISKYKER-RKETERKLERTRENLDRLEDILNELERQlkslerQAEKAERYKELKAELRELelalLVLRLEELREELEEL 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 171 QSEFSAF---LKASDNDRGALLEKLTDTGLYSQLSKAAYQRASQADEQRKQLEQRLEGSLPLAEQARAGLEAALESHAQA 247
Cdd:TIGR02168 245 QEELKEAeeeLEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQ 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 248 RLQEQQALQRLEGQ-QQWFTEEQRLLQSCEHAQGQLAEARQAWDALATERETLQwlerlAPVRGLIERLKQLEQELRHSE 326
Cdd:TIGR02168 325 LEELESKLDELAEElAELEEKLEELKEELESLEAELEELEAELEELESRLEELE-----EQLETLRSKVAQLELQIASLN 399
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 327 QQQRQRTEQQAAGTERLQGLQARLQEARERQAQADNHLRQAQAPL--REAFQLESEARRLERTLAERQELHRQSNQrhaq 404
Cdd:TIGR02168 400 NEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEEleEELEELQEELERLEEALEELREELEEAEQ---- 475
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 405 qsdAARQLDMEQQRHVAEQAQLQAALRDSQALAALGDAWVTHQGQLATFVQRRQRALESQaqlPELEKSLAHAGEPL--- 481
Cdd:TIGR02168 476 ---ALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVD---EGYEAAIEAALGGRlqa 549
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 482 ---ERLQAQWTALHGSEPDDLAARLV-ELRRQTDSleRQQALHKEWQQVLDQRAGLARRLGELDQRMVEQEQALLDlkrq 557
Cdd:TIGR02168 550 vvvENLNAAKKAIAFLKQNELGRVTFlPLDSIKGT--EIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLG---- 623
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 558 GSQCAEEVkaaEQALQVTRELLQRQRLArsasveqlragLVDGEACPVCGSQehpyhhseqllaaLGEHDDQEQVRAEQS 637
Cdd:TIGR02168 624 GVLVVDDL---DNALELAKKLRPGYRIV-----------TLDGDLVRPGGVI-------------TGGSAKTNSSILERR 676
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 638 --LERLRQTLVGLREGYSSQRERLNQSRQEQQELTGQLAALDRQLDqwtlpeelrllQPSAQLEWLAQRLDDLAGQRQQC 715
Cdd:TIGR02168 677 reIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE-----------ELSRQISALRKDLARLEAEVEQL 745
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 716 QRDFDRLIARQRQTQQLQQELRAAETILQQRQQALTEQRQRYEHLQQQVEEDSQQLRpllsdehwqrwqadplrtfQALG 795
Cdd:TIGR02168 746 EERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALR-------------------EALD 806
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 796 ESIEQRRQQQARLQQIEQRLQELKQRCDESSWQLKQSDEQRNEARQAEERAQAELAELNGRLGAHLGQHACAQDWQLSLE 875
Cdd:TIGR02168 807 ELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLE 886
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 876 HAAQAAQSAVETLQAPLDSLREEQLRLAEALEHLQQQRQRQQDEFQRLQADWQAWRER-----QDNLDDsrLDALLGLSE 950
Cdd:TIGR02168 887 EALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERlseeySLTLEE--AEALENKIE 964
|
890
....*....|....*....
gi 15599478 951 EQATQWREQLQRLQEEITR 969
Cdd:TIGR02168 965 DDEEEARRRLKRLENKIKE 983
|
|
| ABC_Rad50 |
cd03240 |
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ... |
1117-1206 |
1.17e-10 |
|
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.
Pssm-ID: 213207 [Multi-domain] Cd Length: 204 Bit Score: 62.24 E-value: 1.17e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 1117 SLSGGETFLISLALALGLASMASSKLRIesLFIDEGFGSLDPESLQLAM-DALDNLQAQG-RKVAVISHVQEMHERIPVQ 1194
Cdd:cd03240 115 RCSGGEKVLASLIIRLALAETFGSNCGI--LALDEPTTNLDEENIEESLaEIIEERKSQKnFQLIVITHDEELVDAADHI 192
|
90
....*....|..
gi 15599478 1195 VRVQREGNGMSS 1206
Cdd:cd03240 193 YRVEKDGRQKSR 204
|
|
| ABC_Rad50 |
cd03240 |
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ... |
3-110 |
1.85e-10 |
|
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.
Pssm-ID: 213207 [Multi-domain] Cd Length: 204 Bit Score: 61.85 E-value: 1.85e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 3 ILAIRLKNLASLAGEQEIDFTReplssaGLFAITGPTGAGKSTVLDALCLALFGSTPRleSTSASSKVPDgrnelssnde 82
Cdd:cd03240 1 IDKLSIRNIRSFHERSEIEFFS------PLTLIVGQNGAGKTTIIEALKYALTGELPP--NSKGGAHDPK---------- 62
|
90 100
....*....|....*....|....*...
gi 15599478 83 rnLLRRGCASGYAEVDFVGIDGHRYRAR 110
Cdd:cd03240 63 --LIREGEVRAQVKLAFENANGKKYTIT 88
|
|
| ABC_Class2 |
cd03227 |
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ... |
1118-1205 |
4.81e-09 |
|
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.
Pssm-ID: 213194 [Multi-domain] Cd Length: 162 Bit Score: 56.60 E-value: 4.81e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 1118 LSGGETFLISLALALGLASMASSKLRIeslfIDEGFGSLDPESLQLAMDALDNLQAQGRKVAVISHVQEMHERIPVQVRV 1197
Cdd:cd03227 78 LSGGEKELSALALILALASLKPRPLYI----LDEIDRGLDPRDGQALAEAILEHLVKGAQVIVITHLPELAELADKLIHI 153
|
....*...
gi 15599478 1198 QREGNGMS 1205
Cdd:cd03227 154 KKVITGVY 161
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
482-1047 |
2.47e-08 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 58.77 E-value: 2.47e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 482 ERLQAQWTALHGSEpddlaARLVELRRQTDSLERQQALHKEWQQVLDQRAGL------------ARRLGELDQRMVEQEQ 549
Cdd:COG4913 228 DALVEHFDDLERAH-----EALEDAREQIELLEPIRELAERYAAARERLAELeylraalrlwfaQRRLELLEAELEELRA 302
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 550 ALLDLKRQGSQCAEEVKAAEQALQVTRELLQRQRLARSASVEQLRAGLVDGEAcpvcgSQEHPYHHSEQLLAALGEHDDQ 629
Cdd:COG4913 303 ELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELE-----ERERRRARLEALLAALGLPLPA 377
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 630 EqvraEQSLERLRQTLVGLREGYSSQRERLnqsRQEQQELTGQLAALDRQLDQwtLPEELRLLQ--PSAQLEWLAQRLDD 707
Cdd:COG4913 378 S----AEEFAALRAEAAALLEALEEELEAL---EEALAEAEAALRDLRRELRE--LEAEIASLErrKSNIPARLLALRDA 448
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 708 LAgqrQQCQRDFDRL--IARQRQTQQLQQE-LRAAETILqqRQQALT---------EQRQRYEHLQQQVEEDSQQLRPLL 775
Cdd:COG4913 449 LA---EALGLDEAELpfVGELIEVRPEEERwRGAIERVL--GGFALTllvppehyaAALRWVNRLHLRGRLVYERVRTGL 523
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 776 SDEHWQRWQADPLRTfqalgesiEQRRQQQARLQQIEQRLQELKQ-RCDESSWQLKQsdeqrnearqaEERA--QAELAE 852
Cdd:COG4913 524 PDPERPRLDPDSLAG--------KLDFKPHPFRAWLEAELGRRFDyVCVDSPEELRR-----------HPRAitRAGQVK 584
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 853 LNGRLGAHLGQHACAQDWQL---------SLEHAAQAAQSAVETLQAPLDSLREEQLRLAEALEHLQQQrqrqqDEFQRL 923
Cdd:COG4913 585 GNGTRHEKDDRRRIRSRYVLgfdnraklaALEAELAELEEELAEAEERLEALEAELDALQERREALQRL-----AEYSWD 659
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 924 QADWQAWRERQDNLDDSRLDALLGLS-----EEQATQWREQLQRLQEEITrqqtlEAERQAQLLQHRRQRPETDREALED 998
Cdd:COG4913 660 EIDVASAEREIAELEAELERLDASSDdlaalEEQLEELEAELEELEEELD-----ELKGEIGRLEKELEQAEEELDELQD 734
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|
gi 15599478 999 NLRQQRERLAASEQAYLET-YSQLQADNQRREQSQALLAELERARAEFRR 1047
Cdd:COG4913 735 RLEAAEDLARLELRALLEErFAAALGDAVERELRENLEERIDALRARLNR 784
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
208-896 |
7.43e-08 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 57.27 E-value: 7.43e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 208 RASQADEQRKQLEQRLEgslplaeQARAGLEAALESHAQARLQEQQALQRLEGQQQWFTEEQRLLQSCEHAQGQLAEARQ 287
Cdd:COG3096 362 RLEEQEEVVEEAAEQLA-------EAEARLEAAEEEVDSLKSQLADYQQALDVQQTRAIQYQQAVQALEKARALCGLPDL 434
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 288 AWDALATERETLQwlerlAPVRGLIERLKQLEQELRHSEQQQR------QRTEQQAAGTERLQGLQAR---LQEARERQA 358
Cdd:COG3096 435 TPENAEDYLAAFR-----AKEQQATEEVLELEQKLSVADAARRqfekayELVCKIAGEVERSQAWQTArelLRRYRSQQA 509
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 359 QADNhLRQAQAPLREAFQLESEARRLERTLAErqelhrqSNQRHAQQSDAARQLDMEQQRHVAEQAQLQAALRDSQA-LA 437
Cdd:COG3096 510 LAQR-LQQLRAQLAELEQRLRQQQNAERLLEE-------FCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEqRS 581
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 438 ALGDAWVTHQGQLATFVQRRQRALESQAQLPELEkslAHAGEPLERLQAQWTALHgsepdDLAARLVELRRQTDSL-ERQ 516
Cdd:COG3096 582 ELRQQLEQLRARIKELAARAPAWLAAQDALERLR---EQSGEALADSQEVTAAMQ-----QLLEREREATVERDELaARK 653
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 517 QALHKEWQQVL------DQR-AGLARRLG-----------------ELDQRMVEQEQALL--DLKRQGSQ------CAEE 564
Cdd:COG3096 654 QALESQIERLSqpggaeDPRlLALAERLGgvllseiyddvtledapYFSALYGPARHAIVvpDLSAVKEQlagledCPED 733
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 565 V---------------KAAEQALQVTRELLQRQ-------------RLARSASVEQLRA---GLVDGEACPVCGSQEHP- 612
Cdd:COG3096 734 LyliegdpdsfddsvfDAEELEDAVVVKLSDRQwrysrfpevplfgRAAREKRLEELRAerdELAEQYAKASFDVQKLQr 813
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 613 -YHHSEQLlaaLGEHDDQE-QVRAEQSLERLRQTLVGLREGYSSQRERLNQSRQEQQELTGQLAALDRQLDQWTLPEElr 690
Cdd:COG3096 814 lHQAFSQF---VGGHLAVAfAPDPEAELAALRQRRSELERELAQHRAQEQQLRQQLDQLKEQLQLLNKLLPQANLLAD-- 888
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 691 llqpsaqlEWLAQRLDDLAGQRQQCQRDfDRLIARQRQTQQLQQELRAAetiLQQRQQALTEQRQRYEHLQQQVEEDSQQ 770
Cdd:COG3096 889 --------ETLADRLEELREELDAAQEA-QAFIQQHGKALAQLEPLVAV---LQSDPEQFEQLQADYLQAKEQQRRLKQQ 956
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 771 LRPLlsDEHWQRwqadplRTFQALGESIEQRRQQQARLQQIEQRLQELKQRCDESSWQLKQSDEQRNEARQ-------AE 843
Cdd:COG3096 957 IFAL--SEVVQR------RPHFSYEDAVGLLGENSDLNEKLRARLEQAEEARREAREQLRQAQAQYSQYNQvlaslksSR 1028
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|...
gi 15599478 844 ERAQAELAELNGRLGAhLGQHACAQdwqlslehAAQAAQSAVETLQAPLDSLR 896
Cdd:COG3096 1029 DAKQQTLQELEQELEE-LGVQADAE--------AEERARIRRDELHEELSQNR 1072
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
556-1192 |
7.45e-08 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 56.70 E-value: 7.45e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 556 RQGSQCAEEVKAAEQALQVTRELLQRQRLARSAsVEQLRAGLVDGEAcpvcgSQEHPYHHSEQLLAALGEHDD-QEQVRA 634
Cdd:COG4717 64 RKPELNLKELKELEEELKEAEEKEEEYAELQEE-LEELEEELEELEA-----ELEELREELEKLEKLLQLLPLyQELEAL 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 635 EQSLERLRQTLVGLREGYSSQRERLNQSRQEQQELTGQLAALDRQLDQWTLPEELRLLQpsaqlewLAQRLDDLAGQRQQ 714
Cdd:COG4717 138 EAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQD-------LAEELEELQQRLAE 210
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 715 cqrdfdrliarqrqtqqlqqelraAETILQQRQQALTEQRQRYEHLQQQVEEDSQQLRplLSDEHWQRWQADPLRTFQAL 794
Cdd:COG4717 211 ------------------------LEEELEEAQEELEELEEELEQLENELEAAALEER--LKEARLLLLIAAALLALLGL 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 795 GESIEQRRQQQARLQQIEQRLQEL-KQRCDESSWQLKQSDEQRNEARQAEERAQAELAELNGRLGAHLGQHACAQDWQLS 873
Cdd:COG4717 265 GGSLLSLILTIAGVLFLVLGLLALlFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLD 344
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 874 LEHAAQAAQSAVETLQAPLDSLREEQLR---LAEALEHLQQQRQRQQDEFQRLQADWQAWRERQDNLDDSRLDALLGLSE 950
Cdd:COG4717 345 RIEELQELLREAEELEEELQLEELEQEIaalLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEA 424
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 951 EQATQWREQLQRLQEEItrqqtleaerqaqllqhrrqrpetdrEALEDNLRQQRERLAASEQAyletYSQLQADNQRREQ 1030
Cdd:COG4717 425 LDEEELEEELEELEEEL--------------------------EELEEELEELREELAELEAE----LEQLEEDGELAEL 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 1031 SQALLAELERARAEFRRWGRLNelIGSSSGDKFRRIAQGYNLDLLVQHSNVQLRQLAR-RYRLQRGGSELGLLVVDTEmg 1109
Cdd:COG4717 475 LQELEELKAELRELAEEWAALK--LALELLEEAREEYREERLPPVLERASEYFSRLTDgRYRLIRIDEDLSLKVDTED-- 550
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 1110 DELRSVYSLSGGETFLISLALALGLASMASSklRIESLFIDEGFGSLDPESLQLAMDALDNLqAQGRKVAVISHVQEMHE 1189
Cdd:COG4717 551 GRTRPVEELSRGTREQLYLALRLALAELLAG--EPLPLILDDAFVNFDDERLRAALELLAEL-AKGRQVIYFTCHEELVE 627
|
...
gi 15599478 1190 RIP 1192
Cdd:COG4717 628 LFQ 630
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
1083-1195 |
1.10e-07 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 52.63 E-value: 1.10e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 1083 LRQLARRYRLQRGGSELGLLVVDTEMGDELRS----VYSLSGGETFLISLALALglasMASSKLriesLFIDEGFGSLDP 1158
Cdd:cd00267 42 LRAIAGLLKPTSGEILIDGKDIAKLPLEELRRrigyVPQLSGGQRQRVALARAL----LLNPDL----LLLDEPTSGLDP 113
|
90 100 110
....*....|....*....|....*....|....*..
gi 15599478 1159 ESLQLAMDALDNLQAQGRKVAVISHVQEMHERIPVQV 1195
Cdd:cd00267 114 ASRERLLELLRELAEEGRTVIIVTHDPELAELAADRV 150
|
|
| ABC_Class2 |
cd03227 |
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ... |
5-97 |
2.40e-07 |
|
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.
Pssm-ID: 213194 [Multi-domain] Cd Length: 162 Bit Score: 51.59 E-value: 2.40e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 5 AIRLKNLASLAGEQEIDFTREPLssaglFAITGPTGAGKSTVLDALCLALFGSTPRLEStsaSSKVPDGRNELSSNDERN 84
Cdd:cd03227 1 KIVLGRFPSYFVPNDVTFGEGSL-----TIITGPNGSGKSTILDAIGLALGGAQSATRR---RSGVKAGCIVAAVSAELI 72
|
90
....*....|...
gi 15599478 85 LLRRGCASGYAEV 97
Cdd:cd03227 73 FTRLQLSGGEKEL 85
|
|
| SbcC |
COG0419 |
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]; |
1027-1184 |
5.18e-07 |
|
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];
Pssm-ID: 440188 [Multi-domain] Cd Length: 204 Bit Score: 51.55 E-value: 5.18e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 1027 RREQSQALlAELERARAEFRRwgRLNELIGSSSGDKFRRIAQGYNLDLLVQHSNVQLRQLARRYRLQRGgselgllvvdt 1106
Cdd:COG0419 85 ERRQGEFA-EFLEAKPSERKE--ALKRLLGLEIYEELKERLKELEEALESALEELAELQKLKQEILAQL----------- 150
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15599478 1107 emgDELRSVYSLSGGETflislaLALGLASMASsklriesLFIDegFGSLDPESLQLAMDALDNLQaqgrkvaVISHV 1184
Cdd:COG0419 151 ---SGLDPIETLSGGER------LRLALADLLS-------LILD--FGSLDEERLERLLDALEELA-------IITHV 203
|
|
| SbcC_Walker_B |
pfam13558 |
SbcC/RAD50-like, Walker B motif; This entry represents the Walker B domain of RAD50 from ... |
1113-1170 |
7.02e-07 |
|
SbcC/RAD50-like, Walker B motif; This entry represents the Walker B domain of RAD50 from eukaryotes and the prokaryotic homolog SbcCD complex subunit C. RAD50-ATPase forms a complex with Mre11-nuclease that detects and processes diverse and obstructed DNA ends. This domain is separated of the Walker A domain by a long coiled-coil domain and forms the nucleotide-binding domain (NBD) when the coiled coils fold back on themselves and bring together Walker A and B domains. Two RAD50-NBDs forms heterotetramers with a Mre11 nuclease dimer that assemble as catalytic head module that binds and cleaves DNA in an ATP-dependent reaction. Through secondary structural analysis, it has been suggested that there is a wide structural conservation in the Rad50/SMC protein family as seen in structural similarities between RAD50's hook and ABC-ATPase MukB's elbow region.
Pssm-ID: 463921 [Multi-domain] Cd Length: 90 Bit Score: 48.39 E-value: 7.02e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15599478 1113 RSVYSLSGGET-FLISLALALGLASMASSKL----RIESLFIDEGFGSLDPESLQLAMDALDN 1170
Cdd:pfam13558 28 RRSGGLSGGEKqLLAYLPLAAALAAQYGSAEgrppAPRLVFLDEAFAKLDEENIRTALELLRA 90
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
112-594 |
1.31e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 53.22 E-value: 1.31e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 112 ETRRSRD-KADGALQKSQQSLQDLETQQMLAANKKSEFREQLEQKLGLNFAQFTRAVLLAQSEFSAFLKASDNDRGA-LL 189
Cdd:PTZ00121 1216 EARKAEDaKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKAdEA 1295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 190 EKLTDTGLYSQLSKAAyQRASQADEQRKQLEQ---RLEGSLPLAEQARAGLEAALESHAQARLQEQQALQRLEGQQQWFT 266
Cdd:PTZ00121 1296 KKAEEKKKADEAKKKA-EEAKKADEAKKKAEEakkKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKE 1374
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 267 EEQRL----------LQSCEHAQGQLAEARQAWDAL---ATERETLQWLERLAPVRGLIERLKQLEQELRHSEQQQRQRT 333
Cdd:PTZ00121 1375 EAKKKadaakkkaeeKKKADEAKKKAEEDKKKADELkkaAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAE 1454
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 334 EQQAAGTERLQGLQARLQEARERQAQADNHLRQAQAPLREAFQLESEARRLERTLAERQELHRQSNQRHAQQSDAARQLD 413
Cdd:PTZ00121 1455 EAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAK 1534
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 414 MEQQRHVAEQAQLQAALRDSQALAALGDAWVTHQGQLATfvQRRQRALESQAQLPELEKSLAHAGEPLERLQAQWTAlhg 493
Cdd:PTZ00121 1535 KADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAE--EDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKA--- 1609
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 494 sepdDLAARLVELRRQTDSLERQQALHKEWQQVLDQRAGLARRLGELDQRMVEQEQALLDLKRQGSQ---CAEEVKAAEQ 570
Cdd:PTZ00121 1610 ----EEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEdkkKAEEAKKAEE 1685
|
490 500
....*....|....*....|....
gi 15599478 571 ALQVTRELLQRQRlARSASVEQLR 594
Cdd:PTZ00121 1686 DEKKAAEALKKEA-EEAKKAEELK 1708
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
112-969 |
2.19e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 52.37 E-value: 2.19e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 112 ETRRSRDKADGALQKSQQSLQDLETQQMLAANKKSEFREQLEQklglnfAQFTRAVLLAQSEFSAFLKASDNDRGALLEK 191
Cdd:TIGR02168 278 ELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEE------LEAQLEELESKLDELAEELAELEEKLEELKE 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 192 LtdtglysqlSKAAYQRASQADEQRKQLEQRLEGSLPLAEQARAGLEAALESHAQARLQEQQA---LQRLEGQQQWFTEE 268
Cdd:TIGR02168 352 E---------LESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLearLERLEDRRERLQQE 422
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 269 QRLLQScEHAQGQLAEARQAWDALATERETLQwlerlAPVRGLIERLKQLEQELRhseqqqrqrteqqaAGTERLQGLQA 348
Cdd:TIGR02168 423 IEELLK-KLEEAELKELQAELEELEEELEELQ-----EELERLEEALEELREELE--------------EAEQALDAAER 482
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 349 RLQEARERQAQADNHLRQAQAPLREAFQLESEARRLERTLAERQEL-HRQSNQRHAQQSDAARQLDMEQQRHVAEQAQLQ 427
Cdd:TIGR02168 483 ELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELiSVDEGYEAAIEAALGGRLQAVVVENLNAAKKAI 562
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 428 AALRDSQALAALGDAWVTHQGQLATFVQRrqRALESQAQLPELEKSLAHAGEPLERLQAQWTAlHGSEPDDLAARLvELR 507
Cdd:TIGR02168 563 AFLKQNELGRVTFLPLDSIKGTEIQGNDR--EILKNIEGFLGVAKDLVKFDPKLRKALSYLLG-GVLVVDDLDNAL-ELA 638
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 508 RQTDSLERQQALHKEWqqvLDQRAGLARRLGELDQRMVEQEQALLDLKRQGSQCAEEVKAAEQALQVTRELLQRQRlars 587
Cdd:TIGR02168 639 KKLRPGYRIVTLDGDL---VRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELE---- 711
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 588 ASVEQLRAGLVDgeacpvcgsQEHPYHHSEQLLAALGehddQEQVRAEQSLERLRQTLVGLREGYSSQRERLNQSRQEQQ 667
Cdd:TIGR02168 712 EELEQLRKELEE---------LSRQISALRKDLARLE----AEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELA 778
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 668 ELTGQLAALDRQLDQWtlpeelrllqpSAQLEWLAQRLDDLAGQRQQCQRDFDRLIARQRQTQQLQQELRAAETILQQRQ 747
Cdd:TIGR02168 779 EAEAEIEELEAQIEQL-----------KEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQI 847
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 748 QALTEQRQRYEHLQqqveEDSQQLRPLLSDEHwQRWQADPLRTFQALGESIEQRRQQQARLQQIEQRLQELKQRCDEssw 827
Cdd:TIGR02168 848 EELSEDIESLAAEI----EELEELIEELESEL-EALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEE--- 919
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 828 qlkqSDEQRNEARQAEERAQAELAELNGRLgahlgqhacAQDWQLSLEHAAQaaqsAVETLQAPLDSLREEQLRLAEALE 907
Cdd:TIGR02168 920 ----LREKLAQLELRLEGLEVRIDNLQERL---------SEEYSLTLEEAEA----LENKIEDDEEEARRRLKRLENKIK 982
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15599478 908 HLQQQRQRQQDEFQRLQadwqawrERQDNLDDSRLDallglseeqATQWREQLQRLQEEITR 969
Cdd:TIGR02168 983 ELGPVNLAAIEEYEELK-------ERYDFLTAQKED---------LTEAKETLEEAIEEIDR 1028
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
340-547 |
3.33e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 51.45 E-value: 3.33e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 340 TERLQGLQARLQEARERQAQADNHLRQAQAplreafqlesearrLERTLAERQELHRQSNQRHAQQSDAArqldmEQQRH 419
Cdd:COG4913 609 RAKLAALEAELAELEEELAEAEERLEALEA--------------ELDALQERREALQRLAEYSWDEIDVA-----SAERE 669
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 420 VAE-QAQLQAALRDSQALAALGDAWVTHQGQLATFVQRRQRALESQAQlpeLEKSLAHAGEPLERLQAQWTALHGSEPDD 498
Cdd:COG4913 670 IAElEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGR---LEKELEQAEEELDELQDRLEAAEDLARLE 746
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 15599478 499 LAARLVELRRQTDSLERQQALHKEWQqvlDQRAGLARRLGELDQRMVEQ 547
Cdd:COG4913 747 LRALLEERFAAALGDAVERELRENLE---ERIDALRARLNRAEEELERA 792
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
834-1047 |
3.40e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 50.92 E-value: 3.40e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 834 EQRNEARQAEERAQAELAELNGRLGAHLGQHACAQDWQLSLEHAAQAAQSAVETLQAPLDSLREEQLRLAEALEHLQQQR 913
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 914 QRQQDEFQRL---------QADWQAWRERQDNLDDSRLDALLGLSEEQATQWREQLQRLQEEITRQQTlEAERQAQLLQH 984
Cdd:COG4942 100 EAQKEELAELlralyrlgrQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRA-ELEAERAELEA 178
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15599478 985 RRQRPETDREALEDNLRQQRERLAASEQAYLETYSQLQADNQRREQSQALLAELERARAEFRR 1047
Cdd:COG4942 179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
|
|
| PksD |
COG3321 |
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites ... |
434-957 |
4.70e-06 |
|
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 442550 [Multi-domain] Cd Length: 1386 Bit Score: 51.03 E-value: 4.70e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 434 QALAALGDAWVT---------HQGQ------LATFVQRRQRALESQAQLPELEKSLAHAGEPLERLQAQWTALHGSEPDD 498
Cdd:COG3321 832 QLLTALAQLWVAgvpvdwsalYPGRgrrrvpLPTYPFQREDAAAALLAAALAAALAAAAALGALLLAALAAALAAALLAL 911
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 499 LAARLVELRRQTDSLERQQALHKEWQQVLDQRAGLARRLGE--LDQRMVEQEQALLDLKRQGSQCAEEVKAAEQALQVTR 576
Cdd:COG3321 912 AAAAAAALALAAAALAALLALVALAAAAAALLALAAAAAAAaaALAAAEAGALLLLAAAAAAAAAAAAAAAAAAAAAAAA 991
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 577 ELLQRQRLARSASVEQLRAGLVDGEACPVCGSQEHPYHHSEQLLAALGEHDDQEQVRAEQSLERLRQTLVGLREGYSSQR 656
Cdd:COG3321 992 AAAALAAAAALALLAAAALLLAAAAAAAALLALAALLAAAAAALAAAAAAAAAAAALAALAAAAAAAAALALALAALLLL 1071
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 657 ERLNQSRQEQQELTGQLAALDRQLDQWTLPEELRLLQPSAQL---------EWLAQRLDDLAGQRQQCQRDFDRLIARQR 727
Cdd:COG3321 1072 AALAELALAAAALALAAALAAAALALALAALAAALLLLALLAalalaaaaaALLALAALLAAAAAAAALAAAAAAAAALA 1151
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 728 QTQQLQQELRAAETILQQRQQALTEQRQRYEHLQQQVEEDSQQLRPLLSDEHWQRWQADPLRTFQALGESIEQRRQQQAR 807
Cdd:COG3321 1152 LAAAAAALAAALAAALLAAAALLLALALALAAALAAALAGLAALLLAALLAALLAALLALALAALAAAAAALLAAAAAAA 1231
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 808 LQQIEQRLQELKQRCDESSWQLKQSDEQRNEARQAEERAQAELAELNGRLGAHLGQHACAQDWQLSLEHAAQAAQSAVET 887
Cdd:COG3321 1232 ALALLALAAAAAAVAALAAAAAALLAALAALALLAAAAGLAALAAAAAAAAAALALAAAAAAAAAALAALLAAAAAAAAA 1311
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 888 LQAPLDSLREEQLRLAEALEHLQQQRQRQQDEFQRLQADWQAWRERQDNLDDSRLDALLGLSEEQATQWR 957
Cdd:COG3321 1312 AAAAAAAAALAAALLAAALAALAAAVAAALALAAAAAAAAAAAAAAAAAAALAAAAGAAAAAAALALAAL 1381
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
658-934 |
6.91e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 50.45 E-value: 6.91e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 658 RLNQSRQEQQELTGQLAALDRQLDQWT--LPE-ELRLLQPSAQLEWLAQRLDDLAGQRQQcqrdfdRLIARQRQTQQLQQ 734
Cdd:TIGR02169 231 EKEALERQKEAIERQLASLEEELEKLTeeISElEKRLEEIEQLLEELNKKIKDLGEEEQL------RVKEKIGELEAEIA 304
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 735 ELRAAETILQQRQQALTEQRQRYEHLQQQVEEDSQQLrpllsDEHWQRWQADPLRTFQALGESIEQRRQQQARLQQIEQR 814
Cdd:TIGR02169 305 SLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEEL-----EREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKE 379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 815 LQELKQRCDESSWQLKQSDEQRNEARQAEERAQAELAELNGRLGAHLGQHACAQDWQLSLEHAAQAAQSAV-------ET 887
Cdd:TIGR02169 380 FAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIkkqewklEQ 459
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 15599478 888 LQAPLDSLREEQLRLAEALEHLQQQRQRQQDEFQRLQADWQAWRERQ 934
Cdd:TIGR02169 460 LAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERV 506
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
179-854 |
7.13e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 50.52 E-value: 7.13e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 179 KASDNDRGALLEKLTDTGLYSQLSKAayQRASQADEQRKQLEQRLEGSLPLAEQARAgLEAALESHAQARLQEqqaLQRL 258
Cdd:PTZ00121 1147 KAEDAKRVEIARKAEDARKAEEARKA--EDAKKAEAARKAEEVRKAEELRKAEDARK-AEAARKAEEERKAEE---ARKA 1220
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 259 EGQQQwfTEEQRllqSCEHAQGQLAEARQAWDALATERETLQWLERLAPVRGLIERLKQLE----QELRHSEQQQRQRTE 334
Cdd:PTZ00121 1221 EDAKK--AEAVK---KAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEarkaDELKKAEEKKKADEA 1295
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 335 QQAAGTERLQGLQARLQEARerqaQADNHLRQAQAPLREAFQLESEArrlertlaerQELHRQSNQRHAQQSDAARQLDM 414
Cdd:PTZ00121 1296 KKAEEKKKADEAKKKAEEAK----KADEAKKKAEEAKKKADAAKKKA----------EEAKKAAEAAKAEAEAAADEAEA 1361
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 415 EQQRhvAEQAQLQAALRDSQALAALGDAWVTHQGQLAtfvqrRQRALESQAQLPELEKSLAhageplERLQAqwtalhgs 494
Cdd:PTZ00121 1362 AEEK--AEAAEKKKEEAKKKADAAKKKAEEKKKADEA-----KKKAEEDKKKADELKKAAA------AKKKA-------- 1420
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 495 epdDLAARLVELRRQTDSLeRQQALHKEWQQVLDQRAGLARRLGELDQRMVEQEQALlDLKRQgsqcAEEVKAAEQALQV 574
Cdd:PTZ00121 1421 ---DEAKKKAEEKKKADEA-KKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKAD-EAKKK----AEEAKKADEAKKK 1491
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 575 TRELLQRQRLARSASVEQLRAGlvdgEAcpvcgSQEHPYHHSEQLLAALGEHDDQEQVRAEQ--SLERLRQTlVGLREGY 652
Cdd:PTZ00121 1492 AEEAKKKADEAKKAAEAKKKAD----EA-----KKAEEAKKADEAKKAEEAKKADEAKKAEEkkKADELKKA-EELKKAE 1561
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 653 SSQRERLNQSRQEQQELTGQLAALDRQLDQWTLPEELRLLQPSAQLEW-LAQRLDDLAGQRQQCQRDFDRLIARQRQTQQ 731
Cdd:PTZ00121 1562 EKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAeEAKKAEEAKIKAEELKKAEEEKKKVEQLKKK 1641
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 732 LQQELRAAEtilqQRQQALTEQRQRYEHLQQQVEEDSQQLRPLLSDEHWQRWQADPLRTFQALGESIEQRRQQQARLQqi 811
Cdd:PTZ00121 1642 EAEEKKKAE----ELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEK-- 1715
|
650 660 670 680
....*....|....*....|....*....|....*....|...
gi 15599478 812 eQRLQELKQRCDESSWQLKQSDEQRNEARQAEERAQAELAELN 854
Cdd:PTZ00121 1716 -KKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKK 1757
|
|
| ABC_SMC_head |
cd03239 |
The SMC head domain belongs to the ATP-binding cassette superfamily; The structural ... |
3-99 |
1.15e-05 |
|
The SMC head domain belongs to the ATP-binding cassette superfamily; The structural maintenance of chromosomes (SMC) proteins are essential for successful chromosome transmission during replication and segregation of the genome in all organisms. SMCs are generally present as single proteins in bacteria, and as at least six distinct proteins in eukaryotes. The proteins range in size from approximately 110 to 170 kDa, and each has five distinct domains: amino- and carboxy-terminal globular domains, which contain sequences characteristic of ATPases, two coiled-coil regions separating the terminal domains , and a central flexible hinge. SMC proteins function together with other proteins in a range of chromosomal transactions, including chromosome condensation, sister-chromatid cohesion, recombination, DNA repair, and epigenetic silencing of gene expression.
Pssm-ID: 213206 [Multi-domain] Cd Length: 178 Bit Score: 47.30 E-value: 1.15e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 3 ILAIRLKNLASLAGEQEIDFtreplsSAGLFAITGPTGAGKSTVLDALCLALFGSTPRLESTSasskvpdgrnELSSNDE 82
Cdd:cd03239 1 IKQITLKNFKSYRDETVVGG------SNSFNAIVGPNGSGKSNIVDAICFVLGGKAAKLRRGS----------LLFLAGG 64
|
90
....*....|....*..
gi 15599478 83 RNllRRGCASGYAEVDF 99
Cdd:cd03239 65 GV--KAGINSASVEITF 79
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
201-724 |
1.53e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 49.53 E-value: 1.53e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 201 LSKAAYQRASQADEQRKQLEQRLEGSLPLAEQARAGLEAALESHAQARLQEQQALQRLEGQQqwfteEQRLLQSCEHAQG 280
Cdd:COG4913 278 RAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDR-----LEQLEREIERLER 352
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 281 QLAEARQAWDALAteretlqwlerlapvrgliERLKQLEQELRHSEqqqrqrteqqaagterlQGLQARLQEARERQAQA 360
Cdd:COG4913 353 ELEERERRRARLE-------------------ALLAALGLPLPASA-----------------EEFAALRAEAAALLEAL 396
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 361 DNHLRQAQAPLREAFQLESEARR-LERTLAERQEL-HRQSN---QRHAQQSDAARQLDMEQQ--RHVAE----------- 422
Cdd:COG4913 397 EEELEALEEALAEAEAALRDLRReLRELEAEIASLeRRKSNipaRLLALRDALAEALGLDEAelPFVGElievrpeeerw 476
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 423 QAQLQAALR--------DSQALAALGDAWVTHQGQLATFVQRRQRALESQAQLPELEKSLAH--------AGEPLERLQA 486
Cdd:COG4913 477 RGAIERVLGgfaltllvPPEHYAAALRWVNRLHLRGRLVYERVRTGLPDPERPRLDPDSLAGkldfkphpFRAWLEAELG 556
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 487 QWTALHGSE-PDDL--------AARLVELRRQTDSLERQQALHKEW---QQVLDQRAGLARRLGELDQRMVEQEQALLDL 554
Cdd:COG4913 557 RRFDYVCVDsPEELrrhpraitRAGQVKGNGTRHEKDDRRRIRSRYvlgFDNRAKLAALEAELAELEEELAEAEERLEAL 636
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 555 KRQGSQCAEEVKAAEQALQVTRELLQRQRLARS-ASVEQLRAGLVDGEAcpvcgsqehpyhhseqLLAALgehdDQEQVR 633
Cdd:COG4913 637 EAELDALQERREALQRLAEYSWDEIDVASAEREiAELEAELERLDASSD----------------DLAAL----EEQLEE 696
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 634 AEQSLERLRQTLVGLREGYSSQRERLNQSRQEQQELTGQLAALDRQLDQWT-------LPEELRLLQPSAQLEWLAQRLD 706
Cdd:COG4913 697 LEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELralleerFAAALGDAVERELRENLEERID 776
|
570
....*....|....*...
gi 15599478 707 DLAGQRQQCQRDFDRLIA 724
Cdd:COG4913 777 ALRARLNRAEEELERAMR 794
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
6-1044 |
1.60e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 49.30 E-value: 1.60e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 6 IRLKNLASLAGEQEIDFTReplssaGLFAITGPTGAGKSTVLDALCLALFGSTPR-LESTSASSKVPDGRNELSSNDern 84
Cdd:TIGR02169 5 IELENFKSFGKKKVIPFSK------GFTVISGPNGSGKSNIGDAILFALGLSSSKaMRAERLSDLISNGKNGQSGNE--- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 85 llrrgcasGYAEVDFvGIDGHRYRARWETRRSRDKADgalqKSQQSLQDLETQqmlaANKKSEFREQLeQKLGLNFAQFT 164
Cdd:TIGR02169 76 --------AYVTVTF-KNDDGKFPDELEVVRRLKVTD----DGKYSYYYLNGQ----RVRLSEIHDFL-AAAGIYPEGYN 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 165 ravLLAQSEFSAFLKASDNDRGALLEKLTDTGLYSQLSKAAYQRASQA-----------DEQRKQLEqRLEGSLPLAEQA 233
Cdd:TIGR02169 138 ---VVLQGDVTDFISMSPVERRKIIDEIAGVAEFDRKKEKALEELEEVeenierldliiDEKRQQLE-RLRREREKAERY 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 234 RAGLEAALESHAQARLQEQQA-----------LQRLEGQQQWFTEE-QRLLQSCEHAQGQLAEARQAWDALaTERETLQW 301
Cdd:TIGR02169 214 QALLKEKREYEGYELLKEKEAlerqkeaierqLASLEEELEKLTEEiSELEKRLEEIEQLLEELNKKIKDL-GEEEQLRV 292
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 302 LERLAPVRGLIERLKQ----LEQELRHSEQQQRQRTEQQAAGTERLQGLQARLQEARERQAQADNHLRQAQAPLREAFQ- 376
Cdd:TIGR02169 293 KEKIGELEAEIASLERsiaeKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAe 372
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 377 ---LESEARRLERTLAERQELHRQSNQRHAQQSDAARQLDMEQQRHVAEQAQLQAALRD-SQALAALGDAWVTHQGQLAT 452
Cdd:TIGR02169 373 leeVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGiEAKINELEEEKEDKALEIKK 452
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 453 FVQRRQRAlesQAQLPELEKSLAHAGEPLERLQaqwtalhgSEPDDLAARLVELRRQTDSLERQQALHKEWQQVLDQRA- 531
Cdd:TIGR02169 453 QEWKLEQL---AADLSKYEQELYDLKEEYDRVE--------KELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIq 521
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 532 ---GLARRLGELDQRMVEQEQALLDLKRQGSQCAEEVKAAEQAlqvtrELLQRQRLARSA--SVEQLRAGLVDGEACPVC 606
Cdd:TIGR02169 522 gvhGTVAQLGSVGERYATAIEVAAGNRLNNVVVEDDAVAKEAI-----ELLKRRKAGRATflPLNKMRDERRDLSILSED 596
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 607 GSQEHPYHhseqllaaLGEHDDQEQVRAEQSlerLRQTLVglREGYSSQRERLNQSRQ-----EQQELTGQLAALDRQLD 681
Cdd:TIGR02169 597 GVIGFAVD--------LVEFDPKYEPAFKYV---FGDTLV--VEDIEAARRLMGKYRMvtlegELFEKSGAMTGGSRAPR 663
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 682 QwtlpEELRLLQPSAQLEWLAQRLDDLAGQRQQCQRDFDRLIARQRQTQQLQQELRAAETILQQRQQALTEQRQRYEHLQ 761
Cdd:TIGR02169 664 G----GILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERL 739
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 762 QQVEEDSQQLrpllsdehwQRWQADPLRTFQALGESIEqrrQQQARLQQIEQRLQELKQRCDESSWQlkQSDEQRNEARQ 841
Cdd:TIGR02169 740 EELEEDLSSL---------EQEIENVKSELKELEARIE---ELEEDLHKLEEALNDLEARLSHSRIP--EIQAELSKLEE 805
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 842 AEERAQAELAELNGRLGAHLGQHACA-------QDWQLSLEHAAQAAQSAVETLQAPLDSLREEQLRLAEALEHLQQQRQ 914
Cdd:TIGR02169 806 EVSRIEARLREIEQKLNRLTLEKEYLekeiqelQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLG 885
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 915 RQQDEFQRLQADWQAWRERQDNLDDSRLDAllglsEEQATQWREQLQRLQEEITR--------QQTLEAERQAQLLQHRR 986
Cdd:TIGR02169 886 DLKKERDELEAQLRELERKIEELEAQIEKK-----RKRLSELKAKLEALEEELSEiedpkgedEEIPEEELSLEDVQAEL 960
|
1050 1060 1070 1080 1090
....*....|....*....|....*....|....*....|....*....|....*....
gi 15599478 987 QRPETDREALED-NLRQQRErLAASEQAYLETYSQLQADNQRREQSQALLAELERARAE 1044
Cdd:TIGR02169 961 QRVEEEIRALEPvNMLAIQE-YEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKRE 1018
|
|
| COG3903 |
COG3903 |
Predicted ATPase [General function prediction only]; |
205-659 |
1.86e-05 |
|
Predicted ATPase [General function prediction only];
Pssm-ID: 443109 [Multi-domain] Cd Length: 933 Bit Score: 49.25 E-value: 1.86e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 205 AYQRASQADEQRKQLEQRLEGSLPLAEQARAGLEAALESHAQARLQEQQALQRLEGQQQWFTEEQrllqscEHAQGQLAE 284
Cdd:COG3903 477 AAERLAEAGERAAARRRHADYYLALAERAAAELRGPDQLAWLARLDAEHDNLRAALRWALAHGDA------ELALRLAAA 550
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 285 ARQAWDALATERETLQWLERLAPVRGLIERLKQLEQELRHSEQQQRQRTEQQAAGTERLQGLQARLQEARERQAQADNHL 364
Cdd:COG3903 551 LAPFWFLRGLLREGRRWLERALAAAGEAAAALAAAAALAAAAAAARAAAAAAAAAAAAAAAAAAAAAAAAAALLLLAALA 630
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 365 RQAQAPLREAFQLESEARRLERTLAERQELHRQSNQRHAQQSDAARQLDMEQQRHVAEQAQLQAALRDSQALAALGDAWV 444
Cdd:COG3903 631 AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAAAAAAAAALAAAAAALAAAAAAAALAAAAAAA 710
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 445 THQGQLATFVQRRQRALESQAQLPELEKSLAHAGEPLERLQAQWTALHGSEPDDLAARLVELRRQTDSLERQQALHKEWQ 524
Cdd:COG3903 711 LAAAAAAAAAAAAAAALLAAAAAAALAAAAAAAALALAAAAAAAAAAAAAAALAAAAAAAALAALLLALAAAAAALAAAA 790
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 525 QVLDQRAGLARRLGELDQRMVEQEQALLDLKRQGSQCAEEVKAAEQALQVTRELLQRQRLARSASVEQLRAGLVDGEACP 604
Cdd:COG3903 791 AAAAAAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAALAAALAAAAAAAAAAAAAAAAAAALAAALAAAAAAAAAAAL 870
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*
gi 15599478 605 VCGSQEHPYHHSEQLLAALGEHDDQEQVRAEQSLERLRQTLVGLREGYSSQRERL 659
Cdd:COG3903 871 AAAAAAAAAAAAALLAAAAAAAAAAAAAAAAAAALAAAAAAAAAAALAAAAAAAA 925
|
|
| AAA_29 |
pfam13555 |
P-loop containing region of AAA domain; |
26-67 |
2.21e-05 |
|
P-loop containing region of AAA domain;
Pssm-ID: 433304 [Multi-domain] Cd Length: 61 Bit Score: 43.36 E-value: 2.21e-05
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 15599478 26 PLSSAGLFAITGPTGAGKSTVLDALcLALFGSTPRLESTSAS 67
Cdd:pfam13555 18 PIDPRGNTLLTGPSGSGKSTLLDAI-QTLLVPAKRARFNKAA 58
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
99-441 |
2.46e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 48.90 E-value: 2.46e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 99 FVGIDGHRYRARWETRRSRDKADGALQKSQQSLQDLETQQMLAANKKSEFREQLEQKLGLNFAQFTRAVLLAQSEFSAFL 178
Cdd:TIGR02168 647 IVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSR 726
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 179 KASDNDRGALLEKLTDTGLYSQLSKAAYQRAsQADEQRKQLEQRLEGSLPLAEQARAGLEAALESHAQARLQEQQALQRL 258
Cdd:TIGR02168 727 QISALRKDLARLEAEVEQLEERIAQLSKELT-ELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREAL 805
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 259 EGQQQWFTEEQRLLQSCEHAQGQLAEARQAWDALATEREtLQWLERLAPVRGLIERLKQLEQELRHSEQQQRQRTEQQAA 338
Cdd:TIGR02168 806 DELRAELTLLNEEAANLRERLESLERRIAATERRLEDLE-EQIEELSEDIESLAAEIEELEELIEELESELEALLNERAS 884
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 339 GTERLQGLQARLQEARERQAQADNHLRQAQAPLREAFQLESEAR-RLERTLAERQELHRQSNqrhAQQSDAARQLDMEQQ 417
Cdd:TIGR02168 885 LEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLElRLEGLEVRIDNLQERLS---EEYSLTLEEAEALEN 961
|
330 340
....*....|....*....|....*
gi 15599478 418 RHVAEQAQLQAALRD-SQALAALGD 441
Cdd:TIGR02168 962 KIEDDEEEARRRLKRlENKIKELGP 986
|
|
| MARTX_Nterm |
NF012221 |
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ... |
180-437 |
2.50e-05 |
|
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.
Pssm-ID: 467957 [Multi-domain] Cd Length: 1848 Bit Score: 49.06 E-value: 2.50e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 180 ASDNDRGALLEKLTDtglySQLSKAAYQRASQADEQRKQLEQRLEGSLplaeQARAGLEAALESHAQARLQEQQALQR-- 257
Cdd:NF012221 1539 ESSQQADAVSKHAKQ----DDAAQNALADKERAEADRQRLEQEKQQQL----AAISGSQSQLESTDQNALETNGQAQRda 1610
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 258 LEGQQQWFTEEqrllqscehaqgqLAEARQAWDAL-----ATERETLQWLERLApvRGLIERL-KQLEQELRHSEQQQRQ 331
Cdd:NF012221 1611 ILEESRAVTKE-------------LTTLAQGLDALdsqatYAGESGDQWRNPFA--GGLLDRVqEQLDDAKKISGKQLAD 1675
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 332 RTEQQAAgteRLQGLQARLQEARERQAQADNHLRQAQAPLREAfQLESEARRLErTLAERQELHRQSNQRHAQQSDAarq 411
Cdd:NF012221 1676 AKQRHVD---NQQKVKDAVAKSEAGVAQGEQNQANAEQDIDDA-KADAEKRKDD-ALAKQNEAQQAESDANAAANDA--- 1747
|
250 260
....*....|....*....|....*.
gi 15599478 412 ldmeQQRhvAEQAQLQAALRDSQALA 437
Cdd:NF012221 1748 ----QSR--GEQDASAAENKANQAQA 1767
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
276-772 |
7.84e-05 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 46.96 E-value: 7.84e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 276 EHAQGQLAEARQAWDALAteretlqwlERLAPVRGLIERLKQLEQELRHSEQQQRQRTEQQAAGTERLQGLQARLQEARE 355
Cdd:PRK02224 223 ERYEEQREQARETRDEAD---------EVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEE 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 356 R--QAQADNHLRQAQAPLREAFQLESEARRLErtLAERQELHRQSNQRHAQQSDAARQlDMEQQRHVAEQAQLQAALRDS 433
Cdd:PRK02224 294 ErdDLLAEAGLDDADAEAVEARREELEDRDEE--LRDRLEECRVAAQAHNEEAESLRE-DADDLEERAEELREEAAELES 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 434 QALAAlgdawvthqgqLATFVQRRQRALESQAQLPELEKSLAHAGEPLERLQAQWTALHgSEPDDLAARLVE----LRRQ 509
Cdd:PRK02224 371 ELEEA-----------REAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELR-EERDELREREAEleatLRTA 438
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 510 TDSLERQQALHKEW------QQVLDqrAGLARRLGELDQRMVEQEQALLDLKRQGSQCAEEVKAAEQALQVTREL--LQR 581
Cdd:PRK02224 439 RERVEEAEALLEAGkcpecgQPVEG--SPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRIerLEE 516
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 582 QRLARSASVEQLRAGLVDGEacpvcgsqehpyHHSEQLLAALGEHDDQEQVRAEQSLErlrqtlvgLREGYSSQRERLNQ 661
Cdd:PRK02224 517 RREDLEELIAERRETIEEKR------------ERAEELRERAAELEAEAEEKREAAAE--------AEEEAEEAREEVAE 576
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 662 SRQEQQELTGQLAALDRQLDQWTLPEELRllqpsAQLEWLAQRLDDLAGQRQQCQrdfDRLiarqrqTQQLQQELRAAET 741
Cdd:PRK02224 577 LNSKLAELKERIESLERIRTLLAAIADAE-----DEIERLREKREALAELNDERR---ERL------AEKRERKRELEAE 642
|
490 500 510
....*....|....*....|....*....|.
gi 15599478 742 ILQQRQQALTEQRQRYEHLQQQVEEDSQQLR 772
Cdd:PRK02224 643 FDEARIEEAREDKERAEEYLEQVEEKLDELR 673
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
828-1060 |
8.46e-05 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 47.25 E-value: 8.46e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 828 QLKQSDEQRNEARQAEERAQAELAELNGRLGAHLGQHACAQDWqLSLEHAAQAAQSAVETLQAPLDSL----REEQLRLA 903
Cdd:COG3096 293 ELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQAASDH-LNLVQTALRQQEKIERYQEDLEELterlEEQEEVVE 371
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 904 EALEHLQQQRQRQQ---DEFQRLQ---ADWQ-----------AWRERQDNLDDSR-LDALLGLSEEQATQWREQLQRLQE 965
Cdd:COG3096 372 EAAEQLAEAEARLEaaeEEVDSLKsqlADYQqaldvqqtraiQYQQAVQALEKARaLCGLPDLTPENAEDYLAAFRAKEQ 451
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 966 EITrQQTLEAERQAQLLQHRRQRPETDREALEdNLRQQRERLAASEQA--YLETYSQLQADNQRREQSQALLAELERARA 1043
Cdd:COG3096 452 QAT-EEVLELEQKLSVADAARRQFEKAYELVC-KIAGEVERSQAWQTAreLLRRYRSQQALAQRLQQLRAQLAELEQRLR 529
|
250
....*....|....*..
gi 15599478 1044 EFRRWGRLNELIGSSSG 1060
Cdd:COG3096 530 QQQNAERLLEEFCQRIG 546
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
738-1043 |
1.19e-04 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 46.48 E-value: 1.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 738 AAETILQQRQQALTEQRQRYEHLQQQVEEDSQQLRPLLSD-----EHWQRwqadpLRTFQALGESIEQRrqqqarlqqiE 812
Cdd:COG3096 289 ELRRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDyqaasDHLNL-----VQTALRQQEKIERY----------Q 353
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 813 QRLQELKQRCDESSWQLKQSDEQRNEARQAEERAQAELAELNGRLG----AHLGQHACAQDWQ----------------- 871
Cdd:COG3096 354 EDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLAdyqqALDVQQTRAIQYQqavqalekaralcglpd 433
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 872 LSLEHAAQAAQSAVETLQAPLDSLR--EEQLRLAEA----LEHLQQQRQRQQDEFQRLQAdWQAWRERQDNLDDSRLDAl 945
Cdd:COG3096 434 LTPENAEDYLAAFRAKEQQATEEVLelEQKLSVADAarrqFEKAYELVCKIAGEVERSQA-WQTARELLRRYRSQQALA- 511
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 946 lglseEQATQWREQLQRLQEEITRQQtlEAERQAQLLQHRRQRPETDREALEDNLRQQRERLAASEQAYLETYSQLQADN 1025
Cdd:COG3096 512 -----QRLQQLRAQLAELEQRLRQQQ--NAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELR 584
|
330
....*....|....*...
gi 15599478 1026 QRREQSQALLAELeRARA 1043
Cdd:COG3096 585 QQLEQLRARIKEL-AARA 601
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
147-1005 |
1.21e-04 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 46.49 E-value: 1.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 147 EFREQLEQKLGLNFAQFTRAVLLAQS-----EFSAFLKASDNDRGALLEKLTDTGLYSQLSKAA---YQRASQADEQRKQ 218
Cdd:PRK04863 280 ERRVHLEEALELRRELYTSRRQLAAEqyrlvEMARELAELNEAESDLEQDYQAASDHLNLVQTAlrqQEKIERYQADLEE 359
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 219 LEQRLEGSLPLAEQARaglEAALESHAQARLQEQQALqRLEGQ----QQWFTEEQRLLQSCEHAQGQLAEARQAWDALAT 294
Cdd:PRK04863 360 LEERLEEQNEVVEEAD---EQQEENEARAEAAEEEVD-ELKSQladyQQALDVQQTRAIQYQQAVQALERAKQLCGLPDL 435
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 295 ERETLQ-WLERL-APVRGLIERLKQLEQELRHSEQQQRQ------RTEQQAAGTERLQGLQ---ARLQEARERQAQADNh 363
Cdd:PRK04863 436 TADNAEdWLEEFqAKEQEATEELLSLEQKLSVAQAAHSQfeqayqLVRKIAGEVSRSEAWDvarELLRRLREQRHLAEQ- 514
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 364 LRQAQAPLREAFQLESEARRLERTLaerqelhRQSNQRHAQQSDAARQLDMEQQRHVAEQAQLQAALRDSQALAALGDAw 443
Cdd:PRK04863 515 LQQLRMRLSELEQRLRQQQRAERLL-------AEFCKRLGKNLDDEDELEQLQEELEARLESLSESVSEARERRMALRQ- 586
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 444 vtHQGQLATFVQR-RQRALESQAQLPELEKSLAHAGEPLERLQAQWTALHgsepdDLAARLVELRRQTDSLERQQalhke 522
Cdd:PRK04863 587 --QLEQLQARIQRlAARAPAWLAAQDALARLREQSGEEFEDSQDVTEYMQ-----QLLERERELTVERDELAARK----- 654
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 523 wQQVLDQRAGLARRLGELDQRMVeqeqalldlkrqgsQCAEEVKA---AEQALQVTREllqrQRLARSASVEQLRAGLVD 599
Cdd:PRK04863 655 -QALDEEIERLSQPGGSEDPRLN--------------ALAERFGGvllSEIYDDVSLE----DAPYFSALYGPARHAIVV 715
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 600 GEACPVcgsqehpyhhSEQLLAALGEHDDQEQVraEQSLERLRQTLVGLREGY------SSQRErLNQSRQEQQELTGQL 673
Cdd:PRK04863 716 PDLSDA----------AEQLAGLEDCPEDLYLI--EGDPDSFDDSVFSVEELEkavvvkIADRQ-WRYSRFPEVPLFGRA 782
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 674 AaldrqldqwtlpEELRLLQPSAQLEWLAQRLDDLAGQRQQCQR---DFDRLIARQRQTQQLQQELRAAETILQQRQQAL 750
Cdd:PRK04863 783 A------------REKRIEQLRAEREELAERYATLSFDVQKLQRlhqAFSRFIGSHLAVAFEADPEAELRQLNRRRVELE 850
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 751 TE----------QRQRYEHLQQQVeEDSQQLRP---LLSDEHWQrwqadplRTFQALGESIEQRRQQQARLQQIEQRLQE 817
Cdd:PRK04863 851 RAladhesqeqqQRSQLEQAKEGL-SALNRLLPrlnLLADETLA-------DRVEEIREQLDEAEEAKRFVQQHGNALAQ 922
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 818 LKQ-----RCDESSWQLKQSDEQRNEARQAEERAQA-ELAELNGRLgAHLGQHACAQDwqlslehaAQAAQSAVETLQAP 891
Cdd:PRK04863 923 LEPivsvlQSDPEQFEQLKQDYQQAQQTQRDAKQQAfALTEVVQRR-AHFSYEDAAEM--------LAKNSDLNEKLRQR 993
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 892 LDSLREEQLRLAEALEHLQQQRQRQQDEFQRLQADWQAWR----ERQDNLDDSRLDALLGLsEEQATQWREQL-QRLQEe 966
Cdd:PRK04863 994 LEQAEQERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRqmlqELKQELQDLGVPADSGA-EERARARRDELhARLSA- 1071
|
890 900 910
....*....|....*....|....*....|....*....
gi 15599478 967 iTRQQTLEAERQAQLLQHRRQRPETDREALEDNLRQQRE 1005
Cdd:PRK04863 1072 -NRSRRNQLEKQLTFCEAEMDNLTKKLRKLERDYHEMRE 1109
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
918-1055 |
1.47e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 46.06 E-value: 1.47e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 918 DEFQRLQADWQAWRERQDNLDDSR--LDALLGLSE--EQATQWREQLQRLQEEITRQQTLEAERQAQLLQHRRQRPETDR 993
Cdd:COG4913 225 EAADALVEHFDDLERAHEALEDAReqIELLEPIRElaERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAEL 304
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15599478 994 EALEDNLRQQRERLAASEQAYLETYSQL-QADNQRREQSQALLAELERARAE-FRRWGRLNELI 1055
Cdd:COG4913 305 ARLEAELERLEARLDALREELDELEAQIrGNGGDRLEQLEREIERLERELEErERRRARLEALL 368
|
|
| COG3899 |
COG3899 |
Predicted ATPase [General function prediction only]; |
363-760 |
1.74e-04 |
|
Predicted ATPase [General function prediction only];
Pssm-ID: 443106 [Multi-domain] Cd Length: 1244 Bit Score: 46.00 E-value: 1.74e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 363 HLRQAQAPLREAFQLESEARRLERTLAERQELHRQSNQRHAQQSDAARQLDMEQQRHVAEQAQLQAALRDSQALAALGDA 442
Cdd:COG3899 845 PLREALELLREALEAGLETGDAALALLALAAAAAAAAAAAALAAAAAAAARLLAAAAAALAAAAAAAALAAAELARLAAA 924
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 443 WVTHQGQLATFVQRRQRALESQAQLPELEKSLAHAGEPLERLQAQW--TALHGSEPDDLAARLVELRRQTDSLERQQALH 520
Cdd:COG3899 925 AAAAAALALAAAAAAAAAAALAAAAAAAALAAALALAAAAAAAAAAalAAAAAAAAAAAAAAAAAALEAAAAALLALLAA 1004
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 521 KEWQQVLDQRAGLARRLGELDQRMVEQEQALLDLKRQGSQCAEEVKAAEQALQVTRELLQRQRLARSASVEQLRAGLVDG 600
Cdd:COG3899 1005 AAAAAAAAAALAAALLAAALAALAAAAAAAALLAAAAALALLAALAAAAAAAAAAAALAAAAALLAAAAAAAAAAAAAAA 1084
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 601 EACPVCGSQEHPYHHSEQLLAALGEHDDQEQVRAEQSLERLRQTLVGLREGYSSQRERLNQSRQEQQELTGQLAALDRQL 680
Cdd:COG3899 1085 AAALAAALAAAALAAAAAAALALAAALAALALAAALAALALAAAARAAAALLLLAAALALALAALLLLAALLLALALLLL 1164
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 681 DQWTLPEELRLLQPSAQLEWLAQRLDDLAGQRQQCQRDFDRLIARQRQTQQLQQELRAAETILQQRQQALTEQRQRYEHL 760
Cdd:COG3899 1165 ALAALALAAALAALAAALLAAAAAAAAAAALLAALLALAARLAALLALALLALEAAALLLLLLLAALALAAALLALRLLA 1244
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
209-438 |
2.53e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 44.75 E-value: 2.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 209 ASQADEQRKQLEQRLEgslplaeQARAGLEAALESHAQARLQEQQALQRLEGQQQWFTEEQRLLQScehAQGQLAEARQA 288
Cdd:COG4942 15 AAAQADAAAEAEAELE-------QLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRA---LEQELAALEAE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 289 WDALATERETLQwlERLAPVRGLIERLKQLEQELRHSEQQQRQRTEQQAAGTERLQGLQARLQEARERQAQADNHLRQAQ 368
Cdd:COG4942 85 LAELEKEIAELR--AELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAEL 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 369 APLREafQLESEARRLERTLAERQELHRQSNQRHAQQSDAARQLDMEQQRHVAEQAQLQAALRDSQALAA 438
Cdd:COG4942 163 AALRA--ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIA 230
|
|
| ABC_SMC_barmotin |
cd03278 |
ATP-binding cassette domain of barmotin, a member of the SMC protein family; Barmotin is a ... |
6-54 |
3.32e-04 |
|
ATP-binding cassette domain of barmotin, a member of the SMC protein family; Barmotin is a tight junction-associated protein expressed in rat epithelial cells which is thought to have an important regulatory role in tight junction barrier function. Barmotin belongs to the SMC protein family. SMC proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).
Pssm-ID: 213245 [Multi-domain] Cd Length: 197 Bit Score: 43.22 E-value: 3.32e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 15599478 6 IRLKNLASLAGEQEIDFTReplssaGLFAITGPTGAGKSTVLDALCLAL 54
Cdd:cd03278 4 LELKGFKSFADKTTIPFPP------GLTAIVGPNGSGKSNIIDAIRWVL 46
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
267-1004 |
3.42e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 45.13 E-value: 3.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 267 EEQRLLQSCEHAQGQLAEARQAWDALATE-RETLQWLERLAPVRGlIERLKQLE-----QELRHSEQQQRQRTEQQAAGT 340
Cdd:PTZ00121 1085 EDNRADEATEEAFGKAEEAKKTETGKAEEaRKAEEAKKKAEDARK-AEEARKAEdarkaEEARKAEDAKRVEIARKAEDA 1163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 341 ERLQgLQARLQEARE-RQAQADNHLRQAQApLREAfqleSEARRLERtlAERQELHRQSNQrhAQQSDAARQLD----ME 415
Cdd:PTZ00121 1164 RKAE-EARKAEDAKKaEAARKAEEVRKAEE-LRKA----EDARKAEA--ARKAEEERKAEE--ARKAEDAKKAEavkkAE 1233
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 416 QQRHVAEQAQLQAALRDSQALAALGDAWVTHQGQLATFVQRRQ-RALESQAQLPELEKS--LAHAGEPLERLQAQWTALH 492
Cdd:PTZ00121 1234 EAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEaRKADELKKAEEKKKAdeAKKAEEKKKADEAKKKAEE 1313
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 493 GSEPDDLAARLVELRRQTDSLERQQALHKEWQQVLD-------QRAGLARRLGELDQRMVEQEQALLD-LKRQgsqcAEE 564
Cdd:PTZ00121 1314 AKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKaeaeaaaDEAEAAEEKAEAAEKKKEEAKKKADaAKKK----AEE 1389
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 565 VKAAEQALQVTRELLQRQRLARSASVEQLRAGLVDGEACPVCGSQEHPYHHSEQLLAALGEHDDQEQVRAEQSLERLRQt 644
Cdd:PTZ00121 1390 KKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEE- 1468
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 645 lvglrEGYSSQRERLNQSRQEQQELTGQLAALDRQLDQWTLPEELRLLQPSAQLEWLAQRLDDLagQRQQCQRDFDRliA 724
Cdd:PTZ00121 1469 -----AKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEA--KKAEEAKKADE--A 1539
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 725 RQRQTQQLQQELRAAETILQQRQQALTEQRQRYEHLQQQVEEDSQQLRpllsdehwqrwQADPLRTFQALGESIEQRRQQ 804
Cdd:PTZ00121 1540 KKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAK-----------KAEEARIEEVMKLYEEEKKMK 1608
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 805 QARLQQIEQ---RLQELKQRCDESSWQLKQSDEQRNEARQAEERAQAElaELNGRLGAHLGQHACAQDWQLS-LEHAAQA 880
Cdd:PTZ00121 1609 AEEAKKAEEakiKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAE--EENKIKAAEEAKKAEEDKKKAEeAKKAEED 1686
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 881 AQSAVETLQAPLDSLRE-EQLRLAEALEHLQQQRQRQQDEFQRLQADwQAWRErqdnlddsrldallglsEEQATQWREQ 959
Cdd:PTZ00121 1687 EKKAAEALKKEAEEAKKaEELKKKEAEEKKKAEELKKAEEENKIKAE-EAKKE-----------------AEEDKKKAEE 1748
|
730 740 750 760
....*....|....*....|....*....|....*....|....*
gi 15599478 960 LQRLQEEITRQQTLEAERQAQLLQHRRQRPETDREALEDNLRQQR 1004
Cdd:PTZ00121 1749 AKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRR 1793
|
|
| COG1106 |
COG1106 |
ATPase/GTPase, AAA15 family [General function prediction only]; |
6-117 |
4.87e-04 |
|
ATPase/GTPase, AAA15 family [General function prediction only];
Pssm-ID: 440723 [Multi-domain] Cd Length: 330 Bit Score: 43.88 E-value: 4.87e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 6 IRLKNLASLAGEQEIDFTREPLSSAGLFAITGPTGAGKSTVLDALclalfgstprlesTSASSKVPDGRNELSSNDERNL 85
Cdd:COG1106 5 FSIENFRSFKDELTLSMVASGLRLLRVNLIYGANASGKSNLLEAL-------------YFLRNLVLNSSQPGDKLVEPFL 71
|
90 100 110
....*....|....*....|....*....|....
gi 15599478 86 LRRGCASGYA--EVDFVgIDGHRYRARWETRRSR 117
Cdd:COG1106 72 LDSESKNEPSefEILFL-LDGVRYEYGFELDKER 104
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
166-411 |
6.13e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 43.60 E-value: 6.13e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 166 AVLLAQSEFSAFLKASDNDRGALLEKLTDTGLYSQLSKAAYQRASQADEQRKQLEQRLEGSLPLAEQARAGLEAALESHA 245
Cdd:COG4942 7 LALLLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELA 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 246 QARLQEQQALQRLEGQQQWFTEEQRLLQScEHAQGQLAEARQAWDALATEReTLQWLERLAPVR-GLIERLKQLEQELRH 324
Cdd:COG4942 87 ELEKEIAELRAELEAQKEELAELLRALYR-LGRQPPLALLLSPEDFLDAVR-RLQYLKYLAPARrEQAEELRADLAELAA 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 325 SEQQQRQRTEQQAAGTERLQGLQARLQEARERQAQADNHLRQAQAPLR-EAFQLESEARRLERTLAERQELHRQSNQRHA 403
Cdd:COG4942 165 LRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAaELAELQQEAEELEALIARLEAEAAAAAERTP 244
|
....*...
gi 15599478 404 QQSDAARQ 411
Cdd:COG4942 245 AAGFAALK 252
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
752-1044 |
8.65e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 43.98 E-value: 8.65e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 752 EQRQRYEHLQQQVEEDSQqlrpllSDEhwQRWQADPLRTFQALGESIEQRRQQQARLQQIEQ--RLQELKQRCDES---S 826
Cdd:PTZ00121 1428 EEKKKADEAKKKAEEAKK------ADE--AKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEakKADEAKKKAEEAkkkA 1499
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 827 WQLKQSDEQR---NEARQAEERAQAELAElngrlgahlgqhacaqdwqlslehAAQAAQSAVETLQAPlDSLREEQLRLA 903
Cdd:PTZ00121 1500 DEAKKAAEAKkkaDEAKKAEEAKKADEAK------------------------KAEEAKKADEAKKAE-EKKKADELKKA 1554
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 904 EAL---EHLQQQRQRQQDEFQRLQADWQAWRERQdnLDDSRLDALLGLSEEQATQWREQLQRLQEEITRQQTL--EAERQ 978
Cdd:PTZ00121 1555 EELkkaEEKKKAEEAKKAEEDKNMALRKAEEAKK--AEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELkkAEEEK 1632
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15599478 979 AQLLQHRRQRPETDREALEDNLRQQRERLAASEQAYLETYSQLQADNQRREQSQALLAELERARAE 1044
Cdd:PTZ00121 1633 KKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEA 1698
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
1113-1183 |
9.47e-04 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 42.07 E-value: 9.47e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15599478 1113 RSVYSLSGGETFLISLALALglasMASSKLriesLFIDEGFGSLDPESLQLAMDALDNLQAQGRKVAVISH 1183
Cdd:cd03225 130 RSPFTLSGGQKQRVAIAGVL----AMDPDI----LLLDEPTAGLDPAGRRELLELLKKLKAEGKTIIIVTH 192
|
|
| ABC_RecN |
cd03241 |
ATP-binding cassette domain of RecN; RecN ATPase involved in DNA repair; similar to ABC ... |
6-56 |
1.07e-03 |
|
ATP-binding cassette domain of RecN; RecN ATPase involved in DNA repair; similar to ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213208 [Multi-domain] Cd Length: 276 Bit Score: 42.57 E-value: 1.07e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 15599478 6 IRLKNLAsLAGEQEIDFtreplsSAGLFAITGPTGAGKSTVLDALcLALFG 56
Cdd:cd03241 4 LSIKNFA-LIEELELDF------EEGLTVLTGETGAGKSILLDAL-SLLLG 46
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
6-1047 |
1.14e-03 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 43.42 E-value: 1.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 6 IRLKNLASLAGEQEIDFTReplssaGLFAITGPTGAGKSTVLDALCLALFgstprlESTSASSKVPDGRNELSSNDERNL 85
Cdd:pfam02463 5 IEIEGFKSYAKTVILPFSP------GFTAIVGPNGSGKSNILDAILFVLG------ERSAKSLRSERLSDLIHSKSGAFV 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 86 LrrgcaSGYAEVDFVGIDG--HRYRARWETRRSRDKADG---ALQKSQQSLQDLetqqmlaankKSEFREQLEQKLGLNF 160
Cdd:pfam02463 73 N-----SAEVEITFDNEDHelPIDKEEVSIRRRVYRGGDseyYINGKNVTKKEV----------AELLESQGISPEAYNF 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 161 aqftravLLAQSEFSAFLKASDNDRGALLEKLTDTGLYSQLSKAAYQ----RASQADEQRKQLEQRLEgSLPLAEQARAG 236
Cdd:pfam02463 138 -------LVQGGKIEIIAMMKPERRLEIEEEAAGSRLKRKKKEALKKlieeTENLAELIIDLEELKLQ-ELKLKEQAKKA 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 237 LeaaleshaqaRLQEQQALQRLEGQQQWFTEEQRLLQSCEHAQGQLAEARQAWDALATERETlqwlerlapvrgLIERLK 316
Cdd:pfam02463 210 L----------EYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIE------------KEEEKL 267
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 317 QLEQELRHSEQQQRQRTEQQAAGTERLQGLQARLQEARERQAQADNhlrqaqaplREAFQLESEARRLERTLAERQELhr 396
Cdd:pfam02463 268 AQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDE---------EKLKESEKEKKKAEKELKKEKEE-- 336
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 397 QSNQRHAQQSDAARQLDMEQQRHVAEQAQLQAALRDSQALAALGDAWVTHQGQLATFVQRRQRALESQAQLPELEKSLAH 476
Cdd:pfam02463 337 IEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQ 416
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 477 AGEPLERLQAQWTALHGSEPDDLAARLVELRRQTDSLERQQALHKEWQQVLDQRAGLARRLGELDQRMVEQEQALLDLKR 556
Cdd:pfam02463 417 LEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLE 496
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 557 QGSQ---CAEEVKAAEQALQVTRELLQRQRLARSASVEQLRAGLVDGEACPVCGSQEHPYH---HSEQLLAALGEHDDQE 630
Cdd:pfam02463 497 ERSQkesKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATAdevEERQKLVRALTELPLG 576
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 631 QVRAEQSLERLRQTLVGLREGYSSQRERLNQSRQEQQELTGQLAA-------LDRQLDQWTLPEELRLLQPSAQLEWLAQ 703
Cdd:pfam02463 577 ARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRakvvegiLKDTELTKLKESAKAKESGLRKGVSLEE 656
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 704 RLDDLAGQRQQCQRDFDRLIARQRQTQQLQQELRAAETILQQRQQALTEQRQRYEHLQQQVEEDSQQLRPLLSDEHWQRW 783
Cdd:pfam02463 657 GLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINE 736
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 784 QADPLRTFQALGESIEQRRQQQARLQQIEQRLQELKQRCDESSWQLKQSDEQRNEARQAEERAQAELAELNgrlgAHLGQ 863
Cdd:pfam02463 737 ELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALE----EELKE 812
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 864 HACAQDWQLSLEHAAQAAQSAVETLQAPLDSLREEQLRLAEALEHLQQQRQRQQDEFQRLQADwQAWRERQDNLDDSRLD 943
Cdd:pfam02463 813 EAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLK-EEELEEQKLKDELESK 891
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 944 ALLGLSEEQATQWREQLQRLQEEITRQQTLEAERQAQLLQHRRQRPETDR-------EALEDNLRQQRERLAASEQAYLE 1016
Cdd:pfam02463 892 EEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLleeadekEKEENNKEEEEERNKRLLLAKEE 971
|
1050 1060 1070
....*....|....*....|....*....|...
gi 15599478 1017 TYSQ--LQADNQRREQSQALLAELERARAEFRR 1047
Cdd:pfam02463 972 LGKVnlMAIEEFEEKEERYNKDELEKERLEEEK 1004
|
|
| PRK10929 |
PRK10929 |
putative mechanosensitive channel protein; Provisional |
316-595 |
1.22e-03 |
|
putative mechanosensitive channel protein; Provisional
Pssm-ID: 236798 [Multi-domain] Cd Length: 1109 Bit Score: 43.12 E-value: 1.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 316 KQLEQELRhseQQQRQRTEQQAAGTERLQGLQARLQEARERQAQADNHLR------QAQAPLREAFQLESEARRLERTLA 389
Cdd:PRK10929 26 KQITQELE---QAKAAKTPAQAEIVEALQSALNWLEERKGSLERAKQYQQvidnfpKLSAELRQQLNNERDEPRSVPPNM 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 390 ERQELHRQSNQRHAQQSDAARQLDMEQQRHV----------AEQAQLQAALRD-SQALAALGDAwVTHQGQlATFVQRRQ 458
Cdd:PRK10929 103 STDALEQEILQVSSQLLEKSRQAQQEQDRAReisdslsqlpQQQTEARRQLNEiERRLQTLGTP-NTPLAQ-AQLTALQA 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 459 RALESQAQLPELEKSLAHAG--EPLERLQAQwtaLHGSEPDDLAARLVELRRQTDSLERQQAlhkewQQVLDQRAGLARR 536
Cdd:PRK10929 181 ESAALKALVDELELAQLSANnrQELARLRSE---LAKKRSQQLDAYLQALRNQLNSQRQREA-----ERALESTELLAEQ 252
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15599478 537 LGELDQRMVEQEQALLDLKRQGSQCAEEV--------KAAEQALQV------TREllQRQRLARSASV-EQLRA 595
Cdd:PRK10929 253 SGDLPKSIVAQFKINRELSQALNQQAQRMdliasqqrQAASQTLQVrqalntLRE--QSQWLGVSNALgEALRA 324
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
199-431 |
1.41e-03 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 43.02 E-value: 1.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 199 SQLSKAAYQRASQADEQRKQLEQ--RLEGSLPL---------AEQARAGLEAALESHAQARlQEQQALQRLEGQ----QQ 263
Cdd:COG3096 853 AQHRAQEQQLRQQLDQLKEQLQLlnKLLPQANLladetladrLEELREELDAAQEAQAFIQ-QHGKALAQLEPLvavlQS 931
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 264 WFTEEQRLLQSCEHAQGQLAEARQAWDAL---ATERETLQWLE---RLAPVRGLIERLKQ----LEQELRHSeqqqrqrt 333
Cdd:COG3096 932 DPEQFEQLQADYLQAKEQQRRLKQQIFALsevVQRRPHFSYEDavgLLGENSDLNEKLRArleqAEEARREA-------- 1003
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 334 eqqaagTERLQGLQARLQEARERQAQADNHLRQAQAPLREAFQ------LESEARRLERTLAERQELHRQSNQRHAQQSd 407
Cdd:COG3096 1004 ------REQLRQAQAQYSQYNQVLASLKSSRDAKQQTLQELEQeleelgVQADAEAEERARIRRDELHEELSQNRSRRS- 1076
|
250 260
....*....|....*....|....
gi 15599478 408 aarQLDMEQQRHVAEQAQLQAALR 431
Cdd:COG3096 1077 ---QLEKQLTRCEAEMDSLQKRLR 1097
|
|
| YbjD |
COG3593 |
Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM ... |
1-54 |
1.43e-03 |
|
Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains [Replication, recombination and repair];
Pssm-ID: 442812 [Multi-domain] Cd Length: 359 Bit Score: 42.30 E-value: 1.43e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 15599478 1 MKILAIRLKNLASLaGEQEIDFtreplsSAGLFAITGPTGAGKSTVLDALCLAL 54
Cdd:COG3593 1 MKLEKIKIKNFRSI-KDLSIEL------SDDLTVLVGENNSGKSSILEALRLLL 47
|
|
| Ras_like_GTPase |
cd00882 |
Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Ras-like ... |
34-124 |
2.01e-03 |
|
Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Ras-like GTPase superfamily. The Ras-like superfamily of small GTPases consists of several families with an extremely high degree of structural and functional similarity. The Ras superfamily is divided into at least four families in eukaryotes: the Ras, Rho, Rab, and Sar1/Arf families. This superfamily also includes proteins like the GTP translation factors, Era-like GTPases, and G-alpha chain of the heterotrimeric G proteins. Members of the Ras superfamily regulate a wide variety of cellular functions: the Ras family regulates gene expression, the Rho family regulates cytoskeletal reorganization and gene expression, the Rab and Sar1/Arf families regulate vesicle trafficking, and the Ran family regulates nucleocytoplasmic transport and microtubule organization. The GTP translation factor family regulates initiation, elongation, termination, and release in translation, and the Era-like GTPase family regulates cell division, sporulation, and DNA replication. Members of the Ras superfamily are identified by the GTP binding site, which is made up of five characteristic sequence motifs, and the switch I and switch II regions.
Pssm-ID: 206648 [Multi-domain] Cd Length: 161 Bit Score: 40.13 E-value: 2.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 34 AITGPTGAGKSTVLDALCLALFGSTPRLESTSASSKVpdGRNELSSNDERNLLrrgcasgyaeVDFVGI-DGHRYRARWE 112
Cdd:cd00882 1 VVVGRGGVGKSSLLNALLGGEVGEVSDVPGTTRDPDV--YVKELDKGKVKLVL----------VDTPGLdEFGGLGREEL 68
|
90
....*....|..
gi 15599478 113 TRRSRDKADGAL 124
Cdd:cd00882 69 ARLLLRGADLIL 80
|
|
| PRK11447 |
PRK11447 |
cellulose synthase subunit BcsC; Provisional |
106-467 |
2.08e-03 |
|
cellulose synthase subunit BcsC; Provisional
Pssm-ID: 183140 [Multi-domain] Cd Length: 1157 Bit Score: 42.38 E-value: 2.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 106 RYRARWETRRSRDKADGALQKSQQSLQDLETQQmlaankKSEFREQLEQKLGLNfaqftravllAQSEFSAFLKASDNDR 185
Cdd:PRK11447 240 KYLQVFSDGDSVAAARSQLAEQQKQLADPAFRA------RAQGLAAVDSGQGGK----------AIPELQQAVRANPKDS 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 186 ---GALLEKLTDTGLYSQlSKAAYQRASQADEQRKQLE--QRLEGS---LPLAEQARAGLEAalESHAQARLQEQQAlqr 257
Cdd:PRK11447 304 ealGALGQAYSQQGDRAR-AVAQFEKALALDPHSSNRDkwESLLKVnryWLLIQQGDAALKA--NNLAQAERLYQQA--- 377
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 258 legQQQWFTEEQRLLqscehAQGQLAEARQawDALATERETLQWLeRLAP-----VRGLIeRLKQLEQELRHSEQQQRQR 332
Cdd:PRK11447 378 ---RQVDNTDSYAVL-----GLGDVAMARK--DYAAAERYYQQAL-RMDPgntnaVRGLA-NLYRQQSPEKALAFIASLS 445
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 333 TEQQAAGTERLQGLQ-ARLQ------EARERQAQADNHLRQAQAPLREAFQLeseARRLERTLaerqelhRQSNQRhaQQ 405
Cdd:PRK11447 446 ASQRRSIDDIERSLQnDRLAqqaealENQGKWAQAAELQRQRLALDPGSVWL---TYRLAQDL-------RQAGQR--SQ 513
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15599478 406 SDAARQLDMEQQRHVAEQAQ-----LQAALRDSQALAALG----DAWVTHQGQLATFVQRRQrALESQAQL 467
Cdd:PRK11447 514 ADALMRRLAQQKPNDPEQVYayglyLSGSDRDRAALAHLNtlprAQWNSNIQELAQRLQSDQ-VLETANRL 583
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1-857 |
2.16e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 42.36 E-value: 2.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 1 MKILAIRLKNLASLAgEQEIDFTReplssaGLFAITGPTGAGKSTVLDALCLALFGSTPRLESTsasskvpdgrneLSSN 80
Cdd:PRK03918 1 MKIEELKIKNFRSHK-SSVVEFDD------GINLIIGQNGSGKSSILEAILVGLYWGHGSKPKG------------LKKD 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 81 DernlLRRGCASGYAEVDFVGIDGHRYRArweTRRSrdKADGALQKSQQSLQDLETQQmlaankkSEFREQLEQKLGLNF 160
Cdd:PRK03918 62 D----FTRIGGSGTEIELKFEKNGRKYRI---VRSF--NRGESYLKYLDGSEVLEEGD-------SSVREWVERLIPYHV 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 161 aqFTRAVLLAQSEFSAFLKaSDNDRGALLEKLTDTGLYSQlskaAYQRASqadEQRKQLEQRLEgslplaeqaragleaA 240
Cdd:PRK03918 126 --FLNAIYIRQGEIDAILE-SDESREKVVRQILGLDDYEN----AYKNLG---EVIKEIKRRIE---------------R 180
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 241 LESHAQArlqEQQALQRLEGQQQWFTEEQRLLQSCEHAQGQLAearqawdalateretlqwlERLAPVRGLIERLKQLEQ 320
Cdd:PRK03918 181 LEKFIKR---TENIEELIKEKEKELEEVLREINEISSELPELR-------------------EELEKLEKEVKELEELKE 238
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 321 ELRHSEQQQRQRTEQQAAGTERLQGLQARLQEARERqaqadnhlrqaqapLREafqLESEARRLERtLAERQELHRQSNQ 400
Cdd:PRK03918 239 EIEELEKELESLEGSKRKLEEKIRELEERIEELKKE--------------IEE---LEEKVKELKE-LKEKAEEYIKLSE 300
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 401 RHAQQSDAARQLDMEQQRHVAEQAQLQAALRDSQALAAlgdawvthqgQLATFVQRRQRALESQAQLPELEKSLAHAGEP 480
Cdd:PRK03918 301 FYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEE----------RLEELKKKLKELEKRLEELEERHELYEEAKAK 370
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 481 LERLQAQWTALHGSEPDDLAARLVELRRQTDSLErqqalhkewqqvlDQRAGLARRLGELDQRMVEQEQALLDLKRQGSQ 560
Cdd:PRK03918 371 KEELERLKKRLTGLTPEKLEKELEELEKAKEEIE-------------EEISKITARIGELKKEIKELKKAIEELKKAKGK 437
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 561 CA------EEVKAAEQALQVTRELLQ-RQRLARSASVE-QLRAGLVDGEACPVCGSQEHPYHH-SEQLLAA---LGEHDD 628
Cdd:PRK03918 438 CPvcgrelTEEHRKELLEEYTAELKRiEKELKEIEEKErKLRKELRELEKVLKKESELIKLKElAEQLKELeekLKKYNL 517
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 629 QEQVRAEQSLERLRQTLVGLRegysSQRERLNQSRQEQQELTGQLAALDRQLDqwTLPEELRLLQpsAQLEWLA-QRLDD 707
Cdd:PRK03918 518 EELEKKAEEYEKLKEKLIKLK----GEIKSLKKELEKLEELKKKLAELEKKLD--ELEEELAELL--KELEELGfESVEE 589
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 708 LAGQRQQCQ---RDFDRLIARQRQTQQLQQELRAAETILQQRQQALTEQRQRYEHLQQQVEEdsqqLRPLLSDEHWQRWQ 784
Cdd:PRK03918 590 LEERLKELEpfyNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEE----LEKKYSEEEYEELR 665
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15599478 785 adplrtfqalgesiEQRRQQQARLQQIEQRLQELKQRCDESSWQLKQSDEQRNEARQAE------ERAQAELAELNGRL 857
Cdd:PRK03918 666 --------------EEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKkeleklEKALERVEELREKV 730
|
|
| KpsE |
COG3524 |
Capsule polysaccharide export protein KpsE/RkpR [Cell wall/membrane/envelope biogenesis]; |
895-1047 |
2.85e-03 |
|
Capsule polysaccharide export protein KpsE/RkpR [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442746 [Multi-domain] Cd Length: 370 Bit Score: 41.37 E-value: 2.85e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 895 LREEQLRLAEAlehlqqQRQRQQDEFQRLQADWQAWRERQDNLDdsrldallglSEEQATQWREQLQRLQEEITRqqtLE 974
Cdd:COG3524 174 AREDAVRFAEE------EVERAEERLRDAREALLAFRNRNGILD----------PEATAEALLQLIATLEGQLAE---LE 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 975 AERQAQLLQHRRQRP-----ETDREALEDNLRQQRERLAASEQ-----AYLETYSQLQADNQRREQS-QALLAELERARA 1043
Cdd:COG3524 235 AELAALRSYLSPNSPqvrqlRRRIAALEKQIAAERARLTGASGgdslaSLLAEYERLELEREFAEKAyTSALAALEQARI 314
|
....
gi 15599478 1044 EFRR 1047
Cdd:COG3524 315 EAAR 318
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
449-1017 |
2.91e-03 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 41.95 E-value: 2.91e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 449 QLATFVQRRQRAleSQAQLPeLEKSLAHAGEPLERLQAQwtaLHGSEPDDLAARLVELRRQ----TDSLERQQALHKEWQ 524
Cdd:PRK02224 160 QLGKLEEYRERA--SDARLG-VERVLSDQRGSLDQLKAQ---IEEKEEKDLHERLNGLESElaelDEEIERYEEQREQAR 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 525 QVLDQRAGLARRLGELDQRMVEQEQALLDLKRQGSQCAEEVKAAEQALQVTRELLQRQRLARSASVEqlRAGLVDGEACP 604
Cdd:PRK02224 234 ETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLA--EAGLDDADAEA 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 605 VcgsqehpyhhsEQLLAALGEHDDQEQVRAEQ---SLERLRQTLVGLREGYSSQRERLNQSRQEQQELTGQLAAL----- 676
Cdd:PRK02224 312 V-----------EARREELEDRDEELRDRLEEcrvAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAreave 380
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 677 DRQLDQWTLPEELRLLQPS-----AQLEWLAQRLDDLAGQRQQCQRDFDRLIARQRQTQQLQQELRA------------- 738
Cdd:PRK02224 381 DRREEIEELEEEIEELRERfgdapVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEAlleagkcpecgqp 460
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 739 ------AETILQQRQQA--LTEQRQRYEHLQQQVEEDSQQLRPLLSDEHwqrwQADPLR-TFQALGESIEQRRQQQARLq 809
Cdd:PRK02224 461 vegsphVETIEEDRERVeeLEAELEDLEEEVEEVEERLERAEDLVEAED----RIERLEeRREDLEELIAERRETIEEK- 535
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 810 qiEQRLQELKQRCDESSWQLKQSDEQRNEARQAEERAQAELAELNGRLGAHlgqhacaqdwqlsleHAAQAAQSAVETLQ 889
Cdd:PRK02224 536 --RERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAEL---------------KERIESLERIRTLL 598
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 890 APLDSLREEQLRLAEALEHLQQQRQRQQDefqRLQADWQAWRERQDNLDDSRLdallglseEQATQWREQLQRLQEEITR 969
Cdd:PRK02224 599 AAIADAEDEIERLREKREALAELNDERRE---RLAEKRERKRELEAEFDEARI--------EEAREDKERAEEYLEQVEE 667
|
570 580 590 600
....*....|....*....|....*....|....*....|....*....
gi 15599478 970 Q-QTLEAERQAqlLQHRRQRPETDREALEDnLRQQRERLAASEQaYLET 1017
Cdd:PRK02224 668 KlDELREERDD--LQAEIGAVENELEELEE-LRERREALENRVE-ALEA 712
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
1118-1191 |
2.98e-03 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 40.07 E-value: 2.98e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15599478 1118 LSGGETFLISLALALglasMASSKLriesLFIDEGFGSLDPESLQLAMDALDNLQAQGRKVAVISHVQEMHERI 1191
Cdd:cd03230 96 LSGGMKQRLALAQAL----LHDPEL----LILDEPTSGLDPESRREFWELLRELKKEGKTILLSSHILEEAERL 161
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
341-587 |
3.47e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 41.29 E-value: 3.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 341 ERLQGLQARLQEARERQAQADNHLRQAQAplreafQLESEARRLERTLAERQELHRQSNQRHAQQSDAARQLDMEQQRHV 420
Cdd:COG4942 27 AELEQLQQEIAELEKELAALKKEEKALLK------QLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 421 AEQAQLQAALRDSQALAAlgdawvthqgqlatfvQRRQRALESQAQLPELEKSLAHAGEPLERLQAQWTALHgSEPDDLA 500
Cdd:COG4942 101 AQKEELAELLRALYRLGR----------------QPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELR-ADLAELA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 501 ARLVELRRQTDSLERQQALHKEWQQVLDQ-RAGLARRLGELDQRMVEQEQALLDLKRQGSQCAEEVKAAEQALQVTRELL 579
Cdd:COG4942 164 ALRAELEAERAELEALLAELEEERAALEAlKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243
|
....*...
gi 15599478 580 QRQRLARS 587
Cdd:COG4942 244 PAAGFAAL 251
|
|
| ABC_SMC5_euk |
cd03277 |
ATP-binding cassette domain of eukaryotic SMC5 proteins; The structural maintenance of ... |
3-97 |
4.53e-03 |
|
ATP-binding cassette domain of eukaryotic SMC5 proteins; The structural maintenance of chromosomes (SMC) proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).
Pssm-ID: 213244 [Multi-domain] Cd Length: 213 Bit Score: 39.89 E-value: 4.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 3 ILAIRLKNLASLAgeqEIDFTREPlssaGLFAITGPTGAGKSTVLDALCLALFGSTPRLestsasskvpdGRnelsSNDE 82
Cdd:cd03277 3 IVRIKLENFVTYD---ETEFRPGP----SLNMIIGPNGSGKSSIVCAICLGLGGKPKLL-----------GR----AKKV 60
|
90
....*....|....*
gi 15599478 83 RNLLRRGCASGYAEV 97
Cdd:cd03277 61 GEFVKRGCDEGTIEI 75
|
|
| EntF |
COG1020 |
EntF, seryl-AMP synthase component of non-ribosomal peptide synthetase [Secondary metabolites ... |
838-1092 |
5.12e-03 |
|
EntF, seryl-AMP synthase component of non-ribosomal peptide synthetase [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 440643 [Multi-domain] Cd Length: 1329 Bit Score: 41.38 E-value: 5.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 838 EARQAEERAQAELAELNGRLGAHLGQHACAQDWQLSLEHAAQAAQSAVETLQAPLDSLREEQLRLAEALEHLQQQRQRQQ 917
Cdd:COG1020 4 AAAAALPPAAAAAPLPLSAAQQRLWLLLLLLLGSAAYNLALALLLLGLLLVAALLLLAALLARRRRALRTRLRTRAGRPV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 918 DEFQRLQADWQAWRERQDNLDDSRLDALLGLSEEQATQWREQLQRLQEEITRQQTLEAERQAQLLQHRRQRPETDREALE 997
Cdd:COG1020 84 QVIQPVVAAPLPVVVLLVDLEALAEAAAEAAAAAEALAPFDLLRGPLLRLLLLLLLLLLLLLLLALHHIISDGLSDGLLL 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 998 DNLRQQRERLAASEQAYLETYSQLQADNQRREQSQALLAELERARAEFRRWGRLNELIGSSSGDKFRRIAQGYNLDLLVQ 1077
Cdd:COG1020 164 AELLRLYLAAYAGAPLPLPPLPIQYADYALWQREWLQGEELARQLAYWRQQLAGLPPLLELPTDRPRPAVQSYRGARVSF 243
|
250
....*....|....*....
gi 15599478 1078 HSNV----QLRQLARRYRL 1092
Cdd:COG1020 244 RLPAeltaALRALARRHGV 262
|
|
| Spy |
COG3914 |
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ... |
353-573 |
5.59e-03 |
|
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443119 [Multi-domain] Cd Length: 658 Bit Score: 40.75 E-value: 5.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 353 ARERQAQADNHLRQAQAPLREAFQLESEARRLERTLAERQELHRQSNQRHAQQSDAARQLDMeqqrHVAEQAQLQAALRD 432
Cdd:COG3914 1 AAAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLAL----AAGEAAAAAAALLL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 433 SQALAALGDAWVTHQGQLATFVQRRQRALESQAQLPELEKSLAHAGEPLERLQAQWTALH---GSEPDDLAA--RLVELR 507
Cdd:COG3914 77 LAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRralALNPDFAEAylNLGEAL 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15599478 508 RQTDSLErqQALhKEWQQVLDQRAGLA---RRLGeldqrmveqeQALLDLKRQgsqcAEEVKAAEQALQ 573
Cdd:COG3914 157 RRLGRLE--EAI-AALRRALELDPDNAealNNLG----------NALQDLGRL----EEAIAAYRRALE 208
|
|
| cbiO |
PRK13631 |
cobalt transporter ATP-binding subunit; Provisional |
1113-1186 |
6.35e-03 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 40.22 E-value: 6.35e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15599478 1113 RSVYSLSGGETFLISLALALGLASmassklriESLFIDEGFGSLDPESLQLAMDALDNLQAQGRKVAVISHVQE 1186
Cdd:PRK13631 172 RSPFGLSGGQKRRVAIAGILAIQP--------EILIFDEPTAGLDPKGEHEMMQLILDAKANNKTVFVITHTME 237
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
1113-1183 |
6.46e-03 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 39.62 E-value: 6.46e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15599478 1113 RSVYSLSGGETFLISLALALglaSMASsklriESLFIDEGFGSLDPESLQLAMDALDNLQAQGRKVAVISH 1183
Cdd:COG1122 130 RPPHELSGGQKQRVAIAGVL---AMEP-----EVLVLDEPTAGLDPRGRRELLELLKRLNKEGKTVIIVTH 192
|
|
| ABC_SMC4_euk |
cd03274 |
ATP-binding cassette domain of eukaryotic SMC4 proteins; The structural maintenance of ... |
3-56 |
6.74e-03 |
|
ATP-binding cassette domain of eukaryotic SMC4 proteins; The structural maintenance of chromosomes (SMC) proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).
Pssm-ID: 213241 [Multi-domain] Cd Length: 212 Bit Score: 39.59 E-value: 6.74e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 15599478 3 ILAIRLKNLASLAGEQEI-----DFTreplssaglfAITGPTGAGKSTVLDALcLALFG 56
Cdd:cd03274 3 ITKLVLENFKSYAGEQVIgpfhkSFS----------AIVGPNGSGKSNVIDSM-LFVFG 50
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1-586 |
6.86e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 40.52 E-value: 6.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 1 MKILAIRLKNLASLAgEQEIDFtreplsSAGLFAITGPTGAGKSTVLDALCLALFGstpRLESTSASSKVPDGRNELSSN 80
Cdd:COG4717 1 MKIKELEIYGFGKFR-DRTIEF------SPGLNVIYGPNEAGKSTLLAFIRAMLLE---RLEKEADELFKPQGRKPELNL 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 81 DERNLLRrgcasgyaevdfvgidghryrarwETRRSRDKADGALQKSQQSLQDLETQQMLAANKKSEFREQLEQklgLNF 160
Cdd:COG4717 71 KELKELE------------------------EELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEK---LEK 123
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 161 AQFTRAVLLAQSEFSAFLKASDNDRGALLEKLTDtglYSQLSKAAYQRASQADEQRKQLEQRLEGSLPLAEQARAGLEAA 240
Cdd:COG4717 124 LLQLLPLYQELEALEAELAELPERLEELEERLEE---LRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEE 200
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 241 LESHAQARLQEQQALQRLEgqqqwfteeqrllQSCEHAQGQLAEArQAWDALATERETLQWLERLAPVRGLIERLKQLEQ 320
Cdd:COG4717 201 LEELQQRLAELEEELEEAQ-------------EELEELEEELEQL-ENELEAAALEERLKEARLLLLIAAALLALLGLGG 266
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 321 ELRHSEQQQRQRTEQQAAGTERLQGLQARLQEARERQAQADNHLRQAQaplreafqlESEARRLERTLAERQELHRQSNQ 400
Cdd:COG4717 267 SLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALE---------ELEEEELEELLAALGLPPDLSPE 337
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 401 RHAQQSDAARQLDMEQQRHVAEQAQLQAALRDSQALAALGDAWVTHQGQLATFVQRRQRALESQAQLPELEKSLAHAGEP 480
Cdd:COG4717 338 ELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGE 417
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 481 LERLQAQWTalhgsePDDLAARLVELRRQTDSLERQQALHKEWQQVLDQRAGLARRLGELDQRMVEQEQALLDLKRQGSQ 560
Cdd:COG4717 418 LEELLEALD------EEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQELEELKAELRELAEE 491
|
570 580
....*....|....*....|....*.
gi 15599478 561 cAEEVKAAEQALQVTRELLQRQRLAR 586
Cdd:COG4717 492 -WAALKLALELLEEAREEYREERLPP 516
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
18-55 |
7.01e-03 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 38.38 E-value: 7.01e-03
10 20 30
....*....|....*....|....*....|....*...
gi 15599478 18 QEIDFTrepLSSAGLFAITGPTGAGKSTVLDALCLALF 55
Cdd:cd00267 16 DNVSLT---LKAGEIVALVGPNGSGKSTLLRAIAGLLK 50
|
|
| COG3903 |
COG3903 |
Predicted ATPase [General function prediction only]; |
257-645 |
7.31e-03 |
|
Predicted ATPase [General function prediction only];
Pssm-ID: 443109 [Multi-domain] Cd Length: 933 Bit Score: 40.77 E-value: 7.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 257 RLEGQQQWFTEEQRLLQSCEHAQGQLAEARQAWDALATERETLQWLERLAPVRGLIERLKQLEQELRHSEQQQRQRTEQQ 336
Cdd:COG3903 546 RLAAALAPFWFLRGLLREGRRWLERALAAAGEAAAALAAAAALAAAAAAARAAAAAAAAAAAAAAAAAAAAAAAAAALLL 625
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 337 AAGTERLQGLQARLQEARERQAQADNHLRQAQAPLREAFQLESEARRLERTLAERQELHRQSNQRHAQQSDAARQLDMEQ 416
Cdd:COG3903 626 LAALAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAAAAAAAAALAAAAAALAAAAAAAALAA 705
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 417 QRHVAEQAQLQAALRDSQALAALGDAWVTHQGQLATFVQRRQRALESQAQLPELEKSLAHAGEPLERLQAQWTALHGSEP 496
Cdd:COG3903 706 AAAAALAAAAAAAAAAAAAAALLAAAAAAALAAAAAAAALALAAAAAAAAAAAAAAALAAAAAAAALAALLLALAAAAAA 785
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 497 DDLAARLVELRRQtdsLERQQALHKEWQQVLDQRAGLARRLGELDQRMVEQEQALLDLKRQGSQCAEEVKAAEQALQVTR 576
Cdd:COG3903 786 LAAAAAAAAAAAA---AAAAAAAAAAAAAAAAALAAAAAAAAAAAAALAAALAAAAAAAAAAAAAAAAAAALAAALAAAA 862
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15599478 577 ELLQRQRLARSASVEQLRAGLVDGEACPVCGSQEHPYHHSEQLLAALGEHDDQEQVRAEQSLERLRQTL 645
Cdd:COG3903 863 AAAAAAALAAAAAAAAAAAAALLAAAAAAAAAAAAAAAAAAALAAAAAAAAAAALAAAAAAAAAAAAAA 931
|
|
| COG5283 |
COG5283 |
Phage-related tail protein [Mobilome: prophages, transposons]; |
315-486 |
7.73e-03 |
|
Phage-related tail protein [Mobilome: prophages, transposons];
Pssm-ID: 444094 [Multi-domain] Cd Length: 747 Bit Score: 40.61 E-value: 7.73e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 315 LKQLEQELRHSEQQQRQRTEQQAAGTERLQGLQARLQEARERQAQADNHLRQAQAPLREAFQLEseARRLERTLAERQEL 394
Cdd:COG5283 5 LGAVDKPFKSALESAKQRVAALAQALKALEAPTRALARALERAKQAAARLQTKYNKLRQSLQRL--RQALDQAGIDTRQL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 395 HRQSNQRHAQQSDAARQLDMEQQRHVAEQAQLQAALRDSQALAALGDAWVTHQGQLATFVQRRQRALESQAQLPELeKSL 474
Cdd:COG5283 83 SAAQRRLRSSLEQTNRQLERQQQRLARLGARQDRLKAARARLQRLAGAGAAAAAIGAALAASVKPAIDFEDAMADV-AAT 161
|
170
....*....|..
gi 15599478 475 AHAGEPLERLQA 486
Cdd:COG5283 162 VDLDKSSEQFKA 173
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
1113-1183 |
7.95e-03 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 39.05 E-value: 7.95e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15599478 1113 RSVYSLSGGETFLISLALALglASMAssKLriesLFIDEGFGSLDPESLQLAMDALDNLQAQGRKVAVISH 1183
Cdd:cd03235 128 RQIGELSGGQQQRVLLARAL--VQDP--DL----LLLDEPFAGVDPKTQEDIYELLRELRREGMTILVVTH 190
|
|
| COG3903 |
COG3903 |
Predicted ATPase [General function prediction only]; |
381-749 |
8.23e-03 |
|
Predicted ATPase [General function prediction only];
Pssm-ID: 443109 [Multi-domain] Cd Length: 933 Bit Score: 40.39 E-value: 8.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 381 ARRLERTLAERQELHRQSNQRHAQQSDAARQLDMEQQRHVAEQAQLQAALRDSQALAALGDAWVTHQGQLATFVQRRQRA 460
Cdd:COG3903 565 RRWLERALAAAGEAAAALAAAAALAAAAAAARAAAAAAAAAAAAAAAAAAAAAAAAAALLLLAALAAAAAAAAAAAAAAA 644
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 461 LESQAQLPELEKSLAHAGEPLERLQAQWTALHGSEPDDLAARLVELRRQTDSLERQQALHKEWQQVLDQRAGLARRLGEL 540
Cdd:COG3903 645 AAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAAAAAAAAALAAAAAALAAAAAAAALAAAAAAALAAAAAAAAAAAAA 724
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 541 DQRMVEQEQALLDLKRQGSQCAEEVKAAEQALQVTRELLQRQRLARSASVEQLRAGLVDGEACPVCGSQEHPYHHSEQLL 620
Cdd:COG3903 725 AALLAAAAAAALAAAAAAAALALAAAAAAAAAAAAAAALAAAAAAAALAALLLALAAAAAALAAAAAAAAAAAAAAAAAA 804
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599478 621 AALGEHDDQEQVRAEQSLERLRQTLVGLREGYSSQRERLNQSRQEQQELTGQLAALDRQLDQWTLPEELRLLQPSAQLEW 700
Cdd:COG3903 805 AAAAAAAAAAALAAAAAAAAAAAAALAAALAAAAAAAAAAAAAAAAAAALAAALAAAAAAAAAAALAAAAAAAAAAAAAL 884
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 15599478 701 LAQRLDDLAGQRQQCQRDFDRLIARQRQTQQLQQELRAAETILQQRQQA 749
Cdd:COG3903 885 LAAAAAAAAAAAAAAAAAAALAAAAAAAAAAALAAAAAAAAAAAAAAAA 933
|
|
| |
