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Conserved domains on  [gi|15600233|ref|NP_253727|]
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type 4 fimbrial biogenesis outer membrane protein PilQ [Pseudomonas aeruginosa PAO1]

Protein Classification

type IV pilus secretin PilQ( domain architecture ID 11469174)

type IV pilus secretin PilQ is required for type IV pilus biogenesis and competence, and could function as a pore for exit of the pilus but also as a channel for entry of heme and antimicrobial agents and uptake of transforming DNA

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HofQ COG4796
Type II secretory pathway, component HofQ [Intracellular trafficking, secretion, and vesicular ...
 107-710 0e+00

Type II secretory pathway, component HofQ [Intracellular trafficking, secretion, and vesicular transport];


:

Pssm-ID: 443824 [Multi-domain]  Cd Length: 570  Bit Score: 788.67  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233 107 LSSYTTRVEGNNLFVVVGNSPAGASVASAAPVKASPAPASyaqpikpkpyvpagrAIRNIDFQRGEKGEGNVVIDLSDPT 186
Cdd:COG4796   1 PVPYETRVEGNALLVTLGPAAAAAAAAAAAFAEAAAAAAN---------------AIRDIDFRRGEDGEGRVVVDLSDPG 65

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233 187 LSPDIQEQGGKIRLDFAKTQLPDALRVRLDVKDFATPVQFVNASAQSDRTSITIEPSGLYDYLVYQTDNRLTVSIKPMTT 266
Cdd:COG4796  66 VGVDIRQQGGKLVVDFLNTSLPEELRRRLDVTDFATPVQSIDAFQQGDNVRLVIEPRGDWEYSAYQTDNQFVVEVKPLTE 145

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233 267 EDAERRKKDNFAYTGEKLSLNFQDIDVRSVLQLIADFTDLNLVASDTVQGNITLRLQNVPWDQALDLVLKTKGLDKRKLG 346
Cdd:COG4796 146 DENKLAQGGKKGYTGEKLSLNFQDIPVRSVLQLIADFTGLNLVISDSVTGNITLRLKNVPWDQALDIILKAKGLDKRKNG 225

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233 347 NVLLVAPADEIAARERQELEAQKQIAELAPLRRELIQVNYAKAADIAKLFQsvtsdGGQEGKEGGRGSITVDDRTNSIIA 426
Cdd:COG4796 226 NVLLVAPAEELAAREKLELEAKQQIEELEPLRTEYIQLNYAKASDLAKLLK-----GQRGSLLSERGSVTVDERTNTLIV 300

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233 427 YQPQERLDELRRIVSQLDIPVRQVMIEARIVEANVGYDKSLGVRWGGAYHKGNwsgygkdgnigikdedGMNCGPIAGSC 506
Cdd:COG4796 301 RDTPSKLEEIRRLIAKLDIPVRQVLIEARIVEASDSFSRELGVRWGGSGANGT----------------GNNRGGIGGSL 364

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233 507 TFPTTGT-SKSPSPFVDLGAKDATSGIGIGF--ITDNIILDLQLSAMEKTGNGEIVSQPKVVTSDKETAKILKGSEVPYQ 583
Cdd:COG4796 365 NGTTAGTpLLPDGLNVNLPAANPAGSLGLTLakLGGGRLLDLELSALEAEGKGEIISSPRVITADQQEASIEQGTEIPYQ 444

                       490       500       510       520       530       540       550       560
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233 584 EASSSGATSTSFKEAALSLEVTPQITPDNRIIVEVKVTKDAPDYQNmLNGVPPINKNEVNAKILVNDGETIVIGGVFSNE 663
Cdd:COG4796 445 ESSSSGATSVEFKEAVLSLEVTPQITPDGRIILDLDVSKDSPGETV-AGGVPAIDTKEIKTQVLVENGETVVLGGIYEQT 523

                       570       580       590       600
                ....*....|....*....|....*....|....*....|....*..
gi 15600233 664 QSKSVEKVPFLGELPYLGRLFRRDTVTDRKNELLVFLTPRIMNNQAI 710
Cdd:COG4796 524 ESNSVDKVPFLGDIPLLGWLFKNTTKTDEKRELLIFITPRIVKDALA 570
AMIN pfam11741
AMIN domain; This N-terminal domain of various bacterial protein families is crucial for the ...
 35-123 1.02e-06

AMIN domain; This N-terminal domain of various bacterial protein families is crucial for the targetting of periplasmic or extracellular proteins to specific regions of the bacterial envelope. AMIN is derived from the N-terminal domain of AmiC, an N-acetylmuramoyl-l-alanine amidase of Escherichia coli which localizes to the septal ring during division and plays a key role in the separation of daughter cells. The AMIN domain is present in several protein families besides amidases suggesting that AMIN may represent a general targetting determinant involved in the localization of periplasmic protein complexes.


:

Pssm-ID: 463338  Cd Length: 96  Bit Score: 47.30  E-value: 1.02e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233    35 PGDRVELKLQfdePVAAPRGYTIEQPARIALDLPGVQNKLGTKNRELSVGNTRSVTVV-EAKDRTRLIINL--TALSSYT 111
Cdd:pfam11741   8 DGTELELETS---GGEKYQVFTLSNPNRLVIDIPGAQLGLPLKRIENPSPGIKSVRVGqFDPNTVRVVVDLdgSVLPQVP 84

                          90
                  ....*....|..
gi 15600233   112 TRVEGNNLFVVV 123
Cdd:pfam11741  85 VFKSGEGLVVDL 96
 
Name Accession Description Interval E-value
HofQ COG4796
Type II secretory pathway, component HofQ [Intracellular trafficking, secretion, and vesicular ...
 107-710 0e+00

Type II secretory pathway, component HofQ [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443824 [Multi-domain]  Cd Length: 570  Bit Score: 788.67  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233 107 LSSYTTRVEGNNLFVVVGNSPAGASVASAAPVKASPAPASyaqpikpkpyvpagrAIRNIDFQRGEKGEGNVVIDLSDPT 186
Cdd:COG4796   1 PVPYETRVEGNALLVTLGPAAAAAAAAAAAFAEAAAAAAN---------------AIRDIDFRRGEDGEGRVVVDLSDPG 65

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233 187 LSPDIQEQGGKIRLDFAKTQLPDALRVRLDVKDFATPVQFVNASAQSDRTSITIEPSGLYDYLVYQTDNRLTVSIKPMTT 266
Cdd:COG4796  66 VGVDIRQQGGKLVVDFLNTSLPEELRRRLDVTDFATPVQSIDAFQQGDNVRLVIEPRGDWEYSAYQTDNQFVVEVKPLTE 145

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233 267 EDAERRKKDNFAYTGEKLSLNFQDIDVRSVLQLIADFTDLNLVASDTVQGNITLRLQNVPWDQALDLVLKTKGLDKRKLG 346
Cdd:COG4796 146 DENKLAQGGKKGYTGEKLSLNFQDIPVRSVLQLIADFTGLNLVISDSVTGNITLRLKNVPWDQALDIILKAKGLDKRKNG 225

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233 347 NVLLVAPADEIAARERQELEAQKQIAELAPLRRELIQVNYAKAADIAKLFQsvtsdGGQEGKEGGRGSITVDDRTNSIIA 426
Cdd:COG4796 226 NVLLVAPAEELAAREKLELEAKQQIEELEPLRTEYIQLNYAKASDLAKLLK-----GQRGSLLSERGSVTVDERTNTLIV 300

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233 427 YQPQERLDELRRIVSQLDIPVRQVMIEARIVEANVGYDKSLGVRWGGAYHKGNwsgygkdgnigikdedGMNCGPIAGSC 506
Cdd:COG4796 301 RDTPSKLEEIRRLIAKLDIPVRQVLIEARIVEASDSFSRELGVRWGGSGANGT----------------GNNRGGIGGSL 364

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233 507 TFPTTGT-SKSPSPFVDLGAKDATSGIGIGF--ITDNIILDLQLSAMEKTGNGEIVSQPKVVTSDKETAKILKGSEVPYQ 583
Cdd:COG4796 365 NGTTAGTpLLPDGLNVNLPAANPAGSLGLTLakLGGGRLLDLELSALEAEGKGEIISSPRVITADQQEASIEQGTEIPYQ 444

                       490       500       510       520       530       540       550       560
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233 584 EASSSGATSTSFKEAALSLEVTPQITPDNRIIVEVKVTKDAPDYQNmLNGVPPINKNEVNAKILVNDGETIVIGGVFSNE 663
Cdd:COG4796 445 ESSSSGATSVEFKEAVLSLEVTPQITPDGRIILDLDVSKDSPGETV-AGGVPAIDTKEIKTQVLVENGETVVLGGIYEQT 523

                       570       580       590       600
                ....*....|....*....|....*....|....*....|....*..
gi 15600233 664 QSKSVEKVPFLGELPYLGRLFRRDTVTDRKNELLVFLTPRIMNNQAI 710
Cdd:COG4796 524 ESNSVDKVPFLGDIPLLGWLFKNTTKTDEKRELLIFITPRIVKDALA 570
IV_pilus_PilQ TIGR02515
type IV pilus secretin (or competence protein) PilQ; A number of proteins homologous to PilQ ...
 281-706 0e+00

type IV pilus secretin (or competence protein) PilQ; A number of proteins homologous to PilQ are involved in type IV pilus formation, competence for transformation, type III secretion, and type II secretion (also called the main terminal branch of the general secretion pathway). Members of this family include PilQ itself, which is a component of the type IV pilus structure, from a number of species. In Haemophilus influenzae, the member of this family is associated with competence for transformation with exogenous DNA rather than with formation of a type IV pilus; the surface structure required for competence may be considered an unusual, incomplete type IV pilus structure. [Cell envelope, Surface structures]


Pssm-ID: 274173 [Multi-domain]  Cd Length: 418  Bit Score: 558.08  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233   281 GEKLSLNFQDIDVRSVLQLIADFTDLNLVASDTVQGNITLRLQNVPWDQALDLVLKTKGLDKRKLGNVLLVAPADEIAAR 360
Cdd:TIGR02515   1 GEKISLNFQDIPVRTVLQVIAEFTGLNIVVSDSVQGNITLRLKNVPWDQALDIVLKSKGLDKRRDGNIIYIAPLDELAAQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233   361 ERQELEAQKQIAELAPLRRELIQVNYAKAADIAKLFQSVTsdGGQEGKEGGRGSITVDDRTNSIIAYQPQERLDELRRIV 440
Cdd:TIGR02515  81 EKDELEAKKQIENLEPLQTELIQLNYAKASDIAKVLTGVT--GGSGGLLSPRGSVTVDPRTNTLIVTDTPENLARIRKLI 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233   441 SQLDIPVRQVMIEARIVEANVGYDKSLGVRWGGAYHKGNWSGYGkdGNIGIKDEDGMNCGPIAGSCTFPTTgtskspsPF 520
Cdd:TIGR02515 159 AELDIPVRQVLIEARIVEATDSFSRELGVRWGITDKNGNGNGTA--GGIGGNNGTTATGAGGTGNPPFGDN-------LN 229

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233   521 VDLGAKDATSGIGI--GFITDNIILDLQLSAMEKTGNGEIVSQPKVVTSDKETAKILKGSEVPYQEASSSGATSTSFKEA 598
Cdd:TIGR02515 230 VNLATATTAAGISFalGKIGSGRLLDLELSALESEGKGEIISSPRVLTANNKEAKIEQGTEIPYQQTSSSGATSVEFKEA 309

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233   599 ALSLEVTPQITPDNRIIVEVKVTKDAPD-YQNMLNGVPPINKNEVNAKILVNDGETIVIGGVFSNEQSKSVEKVPFLGEL 677
Cdd:TIGR02515 310 VLSLEVTPQITPDGRIIMDLLVSKDSPGvVAQAGGGVPAIDKQEINTQVLVKNGETVVIGGIYEQTQTNSEDKVPLLGDI 389

                         410       420
                  ....*....|....*....|....*....
gi 15600233   678 PYLGRLFRRDTVTDRKNELLVFLTPRIMN 706
Cdd:TIGR02515 390 PVLGNLFKKTGKSDEKSELLIFITPRIVN 418
hofQ PRK13568
DNA uptake porin HofQ;
296-705 3.14e-87

DNA uptake porin HofQ;


Pssm-ID: 237430 [Multi-domain]  Cd Length: 381  Bit Score: 278.92  E-value: 3.14e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233  296 VLQLIADFTDLNLVASDTVQGNITLRLQNVPWDQALDLVLKTKGLDKRKLGNVLLVAPADEIAARER-QELEAQKQIAEL 374
Cdd:PRK13568   1 VLQALADYQQLNLVTAPGVGGNLSLRLIEVPWEQALAIILRMGKLSAEREGNVLMVFPEQEIQERQQkTKQQAAPQEQML 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233  375 aPLRRELIQVNYAKAADIAKlfqSVTSDGGQEGKEggRGSITVDDRTNSIIAYQPQERLDELRRIVSQLDIPVRQVMIEA 454
Cdd:PRK13568  81 -PLANLTLTLQYADAEEVAD---SLQSQRGGLLSP--RGSVTADKRTNTLLIRDTPAALAQLKNWLIELDLPLQQVQLAA 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233  455 RIVEANVGYDKSLGVRWG-GAYHKGNWSGYGKDGNIGIkdedgmncgpiagsctfPTtgtskspspfvdlgakdATSGIG 533
Cdd:PRK13568 155 HIVTISSESLQELGVRWGmGEGKQGNTALRINDFNVNL-----------------PL-----------------PNPAAS 200

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233  534 IGFITDNI---ILDLQLSAMEKTGNGEIVSQPKVVTSDKETAKILKGSEVPYQ-EASSSGATSTSFKEAALSLEVTPQIT 609
Cdd:PRK13568 201 AGFHLARLggrLLDLELSALEQENQVDIIASPRLFTSHQQTASIKQGTEIPYTvSSGKSGSTSIEFKEAVLGMEVTPKIL 280

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233  610 PDNRIIVEVKVTKDAPDyQNMLNG---VPPINKNEVNAKILVNDGETIVIGGVFSNEQSKSVEKVPFLGELPYLGRLFRR 686
Cdd:PRK13568 281 RNGRITLKLKISQNMPG-RTIKRGegeMLAIDKQEIQTQVTVKDGETIVLGGIFQQQKRQSVNKVPLLGDIPLLGALFRQ 359

                        410
                 ....*....|....*....
gi 15600233  687 DTVTDRKNELLVFLTPRIM 705
Cdd:PRK13568 360 DTQQQSRRELVIFITPKLI 378
Secretin pfam00263
Bacterial type II and III secretion system protein;
549-705 4.78e-55

Bacterial type II and III secretion system protein;


Pssm-ID: 459738 [Multi-domain]  Cd Length: 159  Bit Score: 185.41  E-value: 4.78e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233   549 AMEKTGNGEIVSQPKVVTSDKETAKILKGSEVPYQEASSSGATSTS---FKEAALSLEVTPQITPDNRIIVEVKVTKDAP 625
Cdd:pfam00263   1 ALEQNGKAKILSSPSLLTLDNQEASIKVGQEVPVPTTSTTGGTTTTtveFKDAGLSLKVTPQVTPDGTITLKINPEVSSP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233   626 DyQNMLNGVPPINKNEVNAKILVNDGETIVIGGVFSNEQSKSVEKVPFLGELPYLGRLFRRDTVTDRKNELLVFLTPRIM 705
Cdd:pfam00263  81 D-GNGGNGVPTINTREISTTVRVKDGQTVVIGGLIQEEDSETESKVPLLGDIPLLGALFRSTSKSKEKTELLIFITPRIV 159
AMIN pfam11741
AMIN domain; This N-terminal domain of various bacterial protein families is crucial for the ...
 35-123 1.02e-06

AMIN domain; This N-terminal domain of various bacterial protein families is crucial for the targetting of periplasmic or extracellular proteins to specific regions of the bacterial envelope. AMIN is derived from the N-terminal domain of AmiC, an N-acetylmuramoyl-l-alanine amidase of Escherichia coli which localizes to the septal ring during division and plays a key role in the separation of daughter cells. The AMIN domain is present in several protein families besides amidases suggesting that AMIN may represent a general targetting determinant involved in the localization of periplasmic protein complexes.


Pssm-ID: 463338  Cd Length: 96  Bit Score: 47.30  E-value: 1.02e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233    35 PGDRVELKLQfdePVAAPRGYTIEQPARIALDLPGVQNKLGTKNRELSVGNTRSVTVV-EAKDRTRLIINL--TALSSYT 111
Cdd:pfam11741   8 DGTELELETS---GGEKYQVFTLSNPNRLVIDIPGAQLGLPLKRIENPSPGIKSVRVGqFDPNTVRVVVDLdgSVLPQVP 84

                          90
                  ....*....|..
gi 15600233   112 TRVEGNNLFVVV 123
Cdd:pfam11741  85 VFKSGEGLVVDL 96
STN smart00965
Secretin and TonB N terminus short domain; This is a short domain found at the N-terminus of ...
 306-354 5.43e-06

Secretin and TonB N terminus short domain; This is a short domain found at the N-terminus of the Secretins of the bacterial type II/III secretory system as well as the TonB-dependent receptor proteins. These proteins are involved in TonB-dependent active uptake of selective substrates.


Pssm-ID: 198033 [Multi-domain]  Cd Length: 52  Bit Score: 44.03  E-value: 5.43e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 15600233    306 LNLVASD-TVQG-NITLRLQNVPWDQALDLVLKTKGLDKRKL-GNVLLVAPA 354
Cdd:smart00965   1 LNFVYDPaLVAGrRVSLLLGNVTVEQALDRLLAGTGLTYRRIgGNTIVLSPA 52
 
Name Accession Description Interval E-value
HofQ COG4796
Type II secretory pathway, component HofQ [Intracellular trafficking, secretion, and vesicular ...
 107-710 0e+00

Type II secretory pathway, component HofQ [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443824 [Multi-domain]  Cd Length: 570  Bit Score: 788.67  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233 107 LSSYTTRVEGNNLFVVVGNSPAGASVASAAPVKASPAPASyaqpikpkpyvpagrAIRNIDFQRGEKGEGNVVIDLSDPT 186
Cdd:COG4796   1 PVPYETRVEGNALLVTLGPAAAAAAAAAAAFAEAAAAAAN---------------AIRDIDFRRGEDGEGRVVVDLSDPG 65

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233 187 LSPDIQEQGGKIRLDFAKTQLPDALRVRLDVKDFATPVQFVNASAQSDRTSITIEPSGLYDYLVYQTDNRLTVSIKPMTT 266
Cdd:COG4796  66 VGVDIRQQGGKLVVDFLNTSLPEELRRRLDVTDFATPVQSIDAFQQGDNVRLVIEPRGDWEYSAYQTDNQFVVEVKPLTE 145

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233 267 EDAERRKKDNFAYTGEKLSLNFQDIDVRSVLQLIADFTDLNLVASDTVQGNITLRLQNVPWDQALDLVLKTKGLDKRKLG 346
Cdd:COG4796 146 DENKLAQGGKKGYTGEKLSLNFQDIPVRSVLQLIADFTGLNLVISDSVTGNITLRLKNVPWDQALDIILKAKGLDKRKNG 225

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233 347 NVLLVAPADEIAARERQELEAQKQIAELAPLRRELIQVNYAKAADIAKLFQsvtsdGGQEGKEGGRGSITVDDRTNSIIA 426
Cdd:COG4796 226 NVLLVAPAEELAAREKLELEAKQQIEELEPLRTEYIQLNYAKASDLAKLLK-----GQRGSLLSERGSVTVDERTNTLIV 300

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233 427 YQPQERLDELRRIVSQLDIPVRQVMIEARIVEANVGYDKSLGVRWGGAYHKGNwsgygkdgnigikdedGMNCGPIAGSC 506
Cdd:COG4796 301 RDTPSKLEEIRRLIAKLDIPVRQVLIEARIVEASDSFSRELGVRWGGSGANGT----------------GNNRGGIGGSL 364

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233 507 TFPTTGT-SKSPSPFVDLGAKDATSGIGIGF--ITDNIILDLQLSAMEKTGNGEIVSQPKVVTSDKETAKILKGSEVPYQ 583
Cdd:COG4796 365 NGTTAGTpLLPDGLNVNLPAANPAGSLGLTLakLGGGRLLDLELSALEAEGKGEIISSPRVITADQQEASIEQGTEIPYQ 444

                       490       500       510       520       530       540       550       560
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233 584 EASSSGATSTSFKEAALSLEVTPQITPDNRIIVEVKVTKDAPDYQNmLNGVPPINKNEVNAKILVNDGETIVIGGVFSNE 663
Cdd:COG4796 445 ESSSSGATSVEFKEAVLSLEVTPQITPDGRIILDLDVSKDSPGETV-AGGVPAIDTKEIKTQVLVENGETVVLGGIYEQT 523

                       570       580       590       600
                ....*....|....*....|....*....|....*....|....*..
gi 15600233 664 QSKSVEKVPFLGELPYLGRLFRRDTVTDRKNELLVFLTPRIMNNQAI 710
Cdd:COG4796 524 ESNSVDKVPFLGDIPLLGWLFKNTTKTDEKRELLIFITPRIVKDALA 570
IV_pilus_PilQ TIGR02515
type IV pilus secretin (or competence protein) PilQ; A number of proteins homologous to PilQ ...
 281-706 0e+00

type IV pilus secretin (or competence protein) PilQ; A number of proteins homologous to PilQ are involved in type IV pilus formation, competence for transformation, type III secretion, and type II secretion (also called the main terminal branch of the general secretion pathway). Members of this family include PilQ itself, which is a component of the type IV pilus structure, from a number of species. In Haemophilus influenzae, the member of this family is associated with competence for transformation with exogenous DNA rather than with formation of a type IV pilus; the surface structure required for competence may be considered an unusual, incomplete type IV pilus structure. [Cell envelope, Surface structures]


Pssm-ID: 274173 [Multi-domain]  Cd Length: 418  Bit Score: 558.08  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233   281 GEKLSLNFQDIDVRSVLQLIADFTDLNLVASDTVQGNITLRLQNVPWDQALDLVLKTKGLDKRKLGNVLLVAPADEIAAR 360
Cdd:TIGR02515   1 GEKISLNFQDIPVRTVLQVIAEFTGLNIVVSDSVQGNITLRLKNVPWDQALDIVLKSKGLDKRRDGNIIYIAPLDELAAQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233   361 ERQELEAQKQIAELAPLRRELIQVNYAKAADIAKLFQSVTsdGGQEGKEGGRGSITVDDRTNSIIAYQPQERLDELRRIV 440
Cdd:TIGR02515  81 EKDELEAKKQIENLEPLQTELIQLNYAKASDIAKVLTGVT--GGSGGLLSPRGSVTVDPRTNTLIVTDTPENLARIRKLI 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233   441 SQLDIPVRQVMIEARIVEANVGYDKSLGVRWGGAYHKGNWSGYGkdGNIGIKDEDGMNCGPIAGSCTFPTTgtskspsPF 520
Cdd:TIGR02515 159 AELDIPVRQVLIEARIVEATDSFSRELGVRWGITDKNGNGNGTA--GGIGGNNGTTATGAGGTGNPPFGDN-------LN 229

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233   521 VDLGAKDATSGIGI--GFITDNIILDLQLSAMEKTGNGEIVSQPKVVTSDKETAKILKGSEVPYQEASSSGATSTSFKEA 598
Cdd:TIGR02515 230 VNLATATTAAGISFalGKIGSGRLLDLELSALESEGKGEIISSPRVLTANNKEAKIEQGTEIPYQQTSSSGATSVEFKEA 309

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233   599 ALSLEVTPQITPDNRIIVEVKVTKDAPD-YQNMLNGVPPINKNEVNAKILVNDGETIVIGGVFSNEQSKSVEKVPFLGEL 677
Cdd:TIGR02515 310 VLSLEVTPQITPDGRIIMDLLVSKDSPGvVAQAGGGVPAIDKQEINTQVLVKNGETVVIGGIYEQTQTNSEDKVPLLGDI 389

                         410       420
                  ....*....|....*....|....*....
gi 15600233   678 PYLGRLFRRDTVTDRKNELLVFLTPRIMN 706
Cdd:TIGR02515 390 PVLGNLFKKTGKSDEKSELLIFITPRIVN 418
hofQ PRK13568
DNA uptake porin HofQ;
296-705 3.14e-87

DNA uptake porin HofQ;


Pssm-ID: 237430 [Multi-domain]  Cd Length: 381  Bit Score: 278.92  E-value: 3.14e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233  296 VLQLIADFTDLNLVASDTVQGNITLRLQNVPWDQALDLVLKTKGLDKRKLGNVLLVAPADEIAARER-QELEAQKQIAEL 374
Cdd:PRK13568   1 VLQALADYQQLNLVTAPGVGGNLSLRLIEVPWEQALAIILRMGKLSAEREGNVLMVFPEQEIQERQQkTKQQAAPQEQML 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233  375 aPLRRELIQVNYAKAADIAKlfqSVTSDGGQEGKEggRGSITVDDRTNSIIAYQPQERLDELRRIVSQLDIPVRQVMIEA 454
Cdd:PRK13568  81 -PLANLTLTLQYADAEEVAD---SLQSQRGGLLSP--RGSVTADKRTNTLLIRDTPAALAQLKNWLIELDLPLQQVQLAA 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233  455 RIVEANVGYDKSLGVRWG-GAYHKGNWSGYGKDGNIGIkdedgmncgpiagsctfPTtgtskspspfvdlgakdATSGIG 533
Cdd:PRK13568 155 HIVTISSESLQELGVRWGmGEGKQGNTALRINDFNVNL-----------------PL-----------------PNPAAS 200

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233  534 IGFITDNI---ILDLQLSAMEKTGNGEIVSQPKVVTSDKETAKILKGSEVPYQ-EASSSGATSTSFKEAALSLEVTPQIT 609
Cdd:PRK13568 201 AGFHLARLggrLLDLELSALEQENQVDIIASPRLFTSHQQTASIKQGTEIPYTvSSGKSGSTSIEFKEAVLGMEVTPKIL 280

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233  610 PDNRIIVEVKVTKDAPDyQNMLNG---VPPINKNEVNAKILVNDGETIVIGGVFSNEQSKSVEKVPFLGELPYLGRLFRR 686
Cdd:PRK13568 281 RNGRITLKLKISQNMPG-RTIKRGegeMLAIDKQEIQTQVTVKDGETIVLGGIFQQQKRQSVNKVPLLGDIPLLGALFRQ 359

                        410
                 ....*....|....*....
gi 15600233  687 DTVTDRKNELLVFLTPRIM 705
Cdd:PRK13568 360 DTQQQSRRELVIFITPKLI 378
hofQ PRK10560
outer membrane porin HofQ; Provisional
 290-708 4.99e-74

outer membrane porin HofQ; Provisional


Pssm-ID: 182549 [Multi-domain]  Cd Length: 386  Bit Score: 244.34  E-value: 4.99e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233  290 DIDVRSVLQLIADFTDLNLVASDTVQGNITLRLQNVPWDQALDLVLKTKGLDKRKLGNVLLVAPAD-EIAARERQELEAQ 368
Cdd:PRK10560   4 DVPVAQVLQALAEQEKLNLVVSPDVSGTVSLHLTDVPWKQALQTVVKSAGLILRQEGNILSVHSQAwQNENIARQEAEQA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233  369 KQIAELaPLRRELIQVNYAKAADIAKLFQSVTSdggqegkegGRGSITVDDRTNSIIAYQPQERLDELRRIVSQLDIPVR 448
Cdd:PRK10560  84 RAQANL-PLENRSITLQYADAGELAKAGEKLLS---------AKGSMTVDKRTNRLLLRDNKTALSALEQWVAQMDLPVG 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233  449 QVMIEARIVEANVGYDKSLGVRWGGAyhkgnwsgygkdgnigikDEDGmncgpiAGSCTFPTTGTSkspspfvDLGAKDA 528
Cdd:PRK10560 154 QVELAAHIVTINEKSLRELGVKWTLA------------------DAQQ------AGGVGQVTTLGS-------DLSVATA 202

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233  529 TSGIG--IGFItDNIILDLQLSAMEKTGNGEIVSQPKVVTSDKETAKILKGSEVPYQ-EASSSGATSTSFKEAALSLEVT 605
Cdd:PRK10560 203 TTRVGfnIGRI-NGRLLDLELSALEQKQQLDIIASPRLLASHLQPASIKQGSEIPYQvSSGESGATSVEFKEAVLGMEVT 281

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233  606 PQITPDNRIIVEVKVTKDAPD--YQNMLNGVPPINKNEVNAKILVNDGETIVIGGVFSNEQSKSVEKVPFLGELPYLGRL 683
Cdd:PRK10560 282 PTVLQKGRIRLKLHISQNVPGqvLQQADGEVLAIDKQEIETQVEVKSGETLALGGIFSRKNKSGQDSVPLLGDIPWLGQL 361

                        410       420
                 ....*....|....*....|....*
gi 15600233  684 FRRDTVTDRKNELLVFLTPRIMNNQ 708
Cdd:PRK10560 362 FRHDGKEDERRELVVFITPRLVSSE 386
PulD COG1450
Type II secretory pathway component GspD/PulD (secretin) [Intracellular trafficking, secretion, ...
 379-709 1.95e-70

Type II secretory pathway component GspD/PulD (secretin) [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 441059 [Multi-domain]  Cd Length: 333  Bit Score: 232.89  E-value: 1.95e-70
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233 379 RELIQVNYAKAADIAKLFQSVTSdggqegkEGGRGSITVDDRTNSIIAYQPQERLDELRRIVSQLDIPVRQVMIEARIVE 458
Cdd:COG1450  17 RDVLRALYADAEDLAKVLRSLLG-------GAAGVSVVADPRTNSLIVRATPEQLREIEELIEQLDVPRRQVLIEAKIVE 89

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233 459 ANVGYDKSLGVRWGGAYHKGNWSGYGKDGNIGikdedgmncgpiagscTFPTTGTskspspfvdlgakdATSGIGIGFIT 538
Cdd:COG1450  90 VSLSDLRELGIDWSALGGNGGGVNFGGTGSLG----------------SLAAAGS--------------LGGGLNLGLLG 139

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233 539 DNIiLDLQLSAMEKTGNGEIVSQPKVVTSDKETAKILKGSEVPYQEASSSGATSTS------FKEAALSLEVTPQITPDN 612
Cdd:COG1450 140 GGN-FGALLNALESNGDANVLSSPSILTLNNQEAVIKVGQTVPYVTGSTTTSSTGNptttieYVDVGITLKVTPQINEDG 218

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233 613 RIIVEVKVTKD--APDYQNMLNGVPPINKNEVNAKILVNDGETIVIGGVFSNEQSKSVEKVPFLGELPYLGRLFRRDTVT 690
Cdd:COG1450 219 TVTLDINPEVSsvTGSTTGGGNGLPTINKREISTTVRVKDGQTVVLGGLIRDEESESESKVPLLGDIPLLGRLFRSTSKS 298

                       330
                ....*....|....*....
gi 15600233 691 DRKNELLVFLTPRIMNNQA 709
Cdd:COG1450 299 KEKTELVIFITPTIIRDGE 317
IV PHA00019
phage assembly protein
 277-706 2.76e-60

phage assembly protein


Pssm-ID: 222772 [Multi-domain]  Cd Length: 428  Bit Score: 208.90  E-value: 2.76e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233  277 FAYTGEKLSLNFQDIDVRSVLQLIADFTDLNLVASDTVQGNITLR---LQNVPWDQALDLVLKTKGLDKRKLGNVLLV-- 351
Cdd:PHA00019  17 LSFSSFALPVELNNSPIREFVSWYSQQTGKSVVLGPDVKGNVTVYsadVNPANLPQFFDSVLRANGFDLVAGGPAVVIkq 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233  352 -----APADEIAARERQE----LEAQKQIAELAPLRRELIQVNYAKAADIAKLFQSVTSDGGQEGkeggrGSITVDDRTN 422
Cdd:PHA00019  97 npnqeDYADDLRDSRDDVfydnSVPSGAPEVPNDLIVRTFNINNVRASDLLPLVKIFVKSNGAPG-----GSVTDLPGTN 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233  423 SIIAYQPQERLDELRRIVSQLDIPVRQVMIEARIVEA----NVGYDKSLGVRWGGAYHKGNWSGygkdgnigikdedgmn 498
Cdd:PHA00019 172 SLVVSGSASQLPALADFISAIDVPRRQVLIEALIFETslgdGVDLSFAAGLASGGKVAGGFNTA---------------- 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233  499 cgpiagsctfpTTGTSKSpspfvdlgakdaTSGIGIGFITDNIiLDLQLSAMEKTGNGEIVSQPKVVTSDKETAKILKGS 578
Cdd:PHA00019 236 -----------RLTTVLS------------SAGGSFGIFNGNV-LGLSVKALENSSNSRVLSRPRILTLSGQSGYISVGQ 291

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233  579 EVPY--------QEASSSGATSTSFKEAALSLEVTPQITPDNRIIVEVKVTKDAPDYQNMLNGVPpINKNEVNAKILVND 650
Cdd:PHA00019 292 NVPFvtgrvtgeAANVNNPFQTIERKDVGVSLEVTPVVMGDGQLVLDIDTKADSLSDSTIASDII-TNQRSLQTTVQVKD 370

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 15600233  651 GETIVIGGVFSNEQSKSVEKVPFLGELPYLGRLFRRDTVTDRKNELLVFLTPRIMN 706
Cdd:PHA00019 371 GQTLLLGGLISSNNTDGDSSVPFLSKIPLIGWLFRSKSDSNEQRTLYVLLTARVIK 426
type_II_gspD TIGR02517
type II secretion system protein D; In Gram-negative bacteria, proteins that have first ...
 344-707 1.79e-59

type II secretion system protein D; In Gram-negative bacteria, proteins that have first crossed the inner member by Sec-dependent protein transport can be exported across the outer membrane by type II secretion, also called the main terminal branch of the general secretion pathway. Members of this family are general secretion pathway protein D. In Yersinia enterocolitica, a second member of this family is part of a novel second type II secretion system specifically associated with virulence (See ). This family is closely homologous to the type IV pilus outer membrane secretin PilQ (TIGR02515) and to the type III secretion system pore YscC/HrcC (TIGR02516). [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274175 [Multi-domain]  Cd Length: 594  Bit Score: 211.09  E-value: 1.79e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233   344 KLGNVLLVAPADEIAARERQELEAQKQIAElAPLRRELIQVNYAKAADIAKLFQSVTSDGGQEGK--------------- 408
Cdd:TIGR02517 202 RRNNILIRAGSPEALERIKKLISQLDVPAS-EGGNVRVYYLRNADAEELAKTLQGVFGGGGNEPGsssspglggavnpgg 280

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233   409 ----------EGGRGSITVDDRTNSIIAYQPQERLDELRRIVSQLDIPVRQVMIEARIVEANVGYDKSLGVRWGGAYHKG 478
Cdd:TIGR02517 281 sqsaqaassaSGGSVSGSADKATNSLIITASPQDYKNIRAVIKQLDVRRAQVLVEAIIVEVSLDDALELGVQWLIAGTGG 360

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233   479 NWSGYGKDGNIGIKDEDGmncgpiagsctfPTTGTSKSPSPFVDLGAKDATSGIGIGFITDNIILdlQLSAMEKTGNGEI 558
Cdd:TIGR02517 361 GVNFSTGSPNSGSLLGAS------------ASAISLGSAGIGLLVTSSSTTSGVGGTGGGPNLGV--LLNALKQDTGFNV 426

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233   559 VSQPKVVTSDKETAKILKGSEVPYQEASSSGATSTS---------FKEAALSLEVTPQITPDNRIIVEVKVTKDAPDYQN 629
Cdd:TIGR02517 427 LSTPSLLTLDNQEAEINVGQEVPVLTGSYNTGTGGTnanpfntyqRKDVGIKLKVTPQINEGGTVRLEIYQEVSSVAPTT 506

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233   630 MLNGV--PPINKNEVNAKILVNDGETIVIGGVFSNEQSKSVEKVPFLGELPYLGRLFRRDTVTDRKNELLVFLTPRIMNN 707
Cdd:TIGR02517 507 VGSAAsgPTFNKREIKTVVLVDNGDTVVLGGLIQDKTSESVTKVPLLGDIPVLGWLFRSTTTERTKTNLMVFITPRIIRD 586
Secretin pfam00263
Bacterial type II and III secretion system protein;
549-705 4.78e-55

Bacterial type II and III secretion system protein;


Pssm-ID: 459738 [Multi-domain]  Cd Length: 159  Bit Score: 185.41  E-value: 4.78e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233   549 AMEKTGNGEIVSQPKVVTSDKETAKILKGSEVPYQEASSSGATSTS---FKEAALSLEVTPQITPDNRIIVEVKVTKDAP 625
Cdd:pfam00263   1 ALEQNGKAKILSSPSLLTLDNQEASIKVGQEVPVPTTSTTGGTTTTtveFKDAGLSLKVTPQVTPDGTITLKINPEVSSP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233   626 DyQNMLNGVPPINKNEVNAKILVNDGETIVIGGVFSNEQSKSVEKVPFLGELPYLGRLFRRDTVTDRKNELLVFLTPRIM 705
Cdd:pfam00263  81 D-GNGGNGVPTINTREISTTVRVKDGQTVVIGGLIQEEDSETESKVPLLGDIPLLGALFRSTSKSKEKTELLIFITPRIV 159
CpaC COG4964
Flp pilus assembly protein, secretin CpaC [Intracellular trafficking, secretion, and vesicular ...
 438-704 1.35e-34

Flp pilus assembly protein, secretin CpaC [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 443990 [Multi-domain]  Cd Length: 456  Bit Score: 137.31  E-value: 1.35e-34
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233 438 RIVSQLDIP-VRQVMIEARIVEANVGYDKSLGVRWGGAYHKGNWSGygkdgnigikdedgmncgPIAGSCTFPTTGTSKS 516
Cdd:COG4964 164 KVINLLTVGgPQQVMLKVRVAEVSRSVLKQLGINWSGLGSSGGFSF------------------GLLTGGLLSGLLGGAT 225

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233 517 PSPFVdlgakdatsgigiGFITDNIILDLQLSAMEKTGNGEIVSQPKVVTSDKETAKILKGSEVPYQEASSSGATSTSFK 596
Cdd:COG4964 226 AGAFS-------------GFGFGNASISATLDALEQNGLARVLAEPNLTALSGETASFLAGGEFPIPVAQGDGTITVEYK 292

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233 597 EAALSLEVTPQITPDNRIIVEVKVTKDAPDYQN--MLNG--VPPINKNEVNAKILVNDGETIVIGGVFSNEQSKSVEKVP 672
Cdd:COG4964 293 EFGVSLNFTPTVLSNGRISLKVAPEVSELDPSNavTLNGitIPGLTTRRAETTVELRSGQSFAIAGLLSSNTRQNVSKVP 372

                       250       260       270
                ....*....|....*....|....*....|..
gi 15600233 673 FLGELPYLGRLFRRDTVTDRKNELLVFLTPRI 704
Cdd:COG4964 373 GLGDIPILGALFRSRSFQRNETELVIIVTPYL 404
type_III_yscC TIGR02516
type III secretion outer membrane pore, YscC/HrcC family; A number of proteins homologous to ...
 345-706 1.67e-32

type III secretion outer membrane pore, YscC/HrcC family; A number of proteins homologous to the type IV pilus secretin PilQ (TIGR02515) are involved in type IV pilus formation, competence for transformation, type III secretion, and type II secretion (also called the main terminal branch of the general secretion pathway). The clade described by this model contains the outer membrane pore proteins of bacterial type III secretion systems, typified by YscC for animal pathogens and HrcC for plant pathogens. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]


Pssm-ID: 274174 [Multi-domain]  Cd Length: 462  Bit Score: 131.34  E-value: 1.67e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233   345 LGNVLLV--APA--DEIAARERQeLEAQKQIAELAPLRRELIQVNYAKAADI--------------AKLFQSVTSdGGQE 406
Cdd:TIGR02516 111 EEGTVYVsgPPAyiDLVRNAATA-LEKQDQGRAGNRQVVKVFPLKYASASDRtynyrdqkvtipgvATILRRLLS-GGRQ 188

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233   407 GKEGGR----GSITVDDRTNSIIAYQPQERLDELRRIVSQLDIPVRQVMIEARIVEANVGYDKSLGVRWGGAYHKGNwsg 482
Cdd:TIGR02516 189 GAGGGRasasPKISADPRTNAVLIRDRPERMAIYEQLIQQLDVPPRLIEISAWIIDIDASDLSQLGVDWQATLGAGD--- 265

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233   483 ygkdgnigikdedgmncgpiagsctfptTGTSKSPSPFVDLGAKDATSGIGIG--FITDniildlqLSAMEKTGNGEIVS 560
Cdd:TIGR02516 266 ----------------------------RQTGFNVSAGAGLGATGSSIVTSDGdyFMAR-------VNALEQTGKAKIVS 310

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233   561 QPKVVTSDKETAkILKGSEVPYQEASSSGATSTSFKEAALSLEVTPQITPDN------RIIVEVKVTKDAPDYQNMLNGV 634
Cdd:TIGR02516 311 RPSVLTLENVQA-VLDNNRTFYVKVSGERVADLESVTAGTSLRVTPRVIGDEgaqrqiKLNVDIEDGQQKTDGTSTVDAL 389

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15600233   635 PPINKNEVNAKILVNDGETIVIGGVFSNEQSKSVEKVPFLGELPYLGRLFRRDTVTDRKNELLVFLTPRIMN 706
Cdd:TIGR02516 390 PEIKRTEINTQARVGHGQSLLIGGYYRDESADSVDGIPLLGDIPLLGNLFRSTSKEKSRVVRLFLITPKIVR 461
Secretin_N pfam03958
Bacterial type II/III secretion system short domain; This is a short, often repeated, domain ...
 380-449 5.77e-13

Bacterial type II/III secretion system short domain; This is a short, often repeated, domain found in bacterial type II/III secretory system proteins. All previous NolW-like domains fall into this family.


Pssm-ID: 461109 [Multi-domain]  Cd Length: 68  Bit Score: 64.16  E-value: 5.77e-13
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233   380 ELIQVNYAKAADIAKLFQSVtsdGGQEGKEGGRGSITVDDRTNSIIAYQPQERLDELRRIVSQLDIPVRQ 449
Cdd:pfam03958   2 RVIPLKYASAEDLASALRSL---LGGSGLLSKRGSVVADPRTNSLIVSGPPEYVELVRQLIKQLDVPRAQ 68
PRK15346 PRK15346
EscC/YscC/HrcC family type III secretion system outer membrane ring protein;
361-688 6.69e-13

EscC/YscC/HrcC family type III secretion system outer membrane ring protein;


Pssm-ID: 237950 [Multi-domain]  Cd Length: 499  Bit Score: 71.65  E-value: 6.69e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233  361 ERQELEAQKQIAELAPLrreliqvNYAKAADIAKLF--QSVTSDG--------------GQEGKEGGRGS--------IT 416
Cdd:PRK15346 167 QAQKRKQNKETVKVFPL-------KYASATDTTYQYrdQNVVVPGvvsvlremaqgnslPLPGSNAVEGSpasqalpvFS 239

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233  417 VDDRTNSIIAYQPQERLDELRRIVSQLDIpvRQVMIE--ARIVEANVGYDKSLGVRWGGAYHKGNwsgygkdgnigikde 494
Cdd:PRK15346 240 ADPRQNAVIVRDRAANMAIYRSLITQLDQ--RPQMIEisVSIIDVDAGDINQLGIDWSASASLGG--------------- 302

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233  495 dgmncgpiaGSCTFPttgtskspSPFVDLGAKDATSGIGIgfiTDNIILdlQLSAMEKTGNGEIVSQPKVVTSDKETAKI 574
Cdd:PRK15346 303 ---------GKISFN--------SGFADGNASGFSTVISN---TGNFMV--RLNALEKNSKAKILSQPSVVTLNNIQAVL 360

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233  575 ---------LKGSEVPYQEASSSgatstsfkeAALsLEVTPQITPDNRIiVEVKVTKDAPDYQ-----NMLNGVPPINKN 640
Cdd:PRK15346 361 dknvtfytkLQGEKVAKLESITT---------GSL-LRVTPRLIDDNGT-QKVMLNLNIQDGQqsatqSETDPLPEVQNS 429

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*...
gi 15600233  641 EVNAKILVNDGETIVIGGVFSNEQSKSVEKVPFLGELPYLGRLFRRDT 688
Cdd:PRK15346 430 EIATQATLKAGQSLLLGGFIQDKQIESQNKIPLLGDIPLIGGLFRSTD 477
AMIN pfam11741
AMIN domain; This N-terminal domain of various bacterial protein families is crucial for the ...
 35-123 1.02e-06

AMIN domain; This N-terminal domain of various bacterial protein families is crucial for the targetting of periplasmic or extracellular proteins to specific regions of the bacterial envelope. AMIN is derived from the N-terminal domain of AmiC, an N-acetylmuramoyl-l-alanine amidase of Escherichia coli which localizes to the septal ring during division and plays a key role in the separation of daughter cells. The AMIN domain is present in several protein families besides amidases suggesting that AMIN may represent a general targetting determinant involved in the localization of periplasmic protein complexes.


Pssm-ID: 463338  Cd Length: 96  Bit Score: 47.30  E-value: 1.02e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233    35 PGDRVELKLQfdePVAAPRGYTIEQPARIALDLPGVQNKLGTKNRELSVGNTRSVTVV-EAKDRTRLIINL--TALSSYT 111
Cdd:pfam11741   8 DGTELELETS---GGEKYQVFTLSNPNRLVIDIPGAQLGLPLKRIENPSPGIKSVRVGqFDPNTVRVVVDLdgSVLPQVP 84

                          90
                  ....*....|..
gi 15600233   112 TRVEGNNLFVVV 123
Cdd:pfam11741  85 VFKSGEGLVVDL 96
PRK15339 PRK15339
EscC/YscC/HrcC family type III secretion system outer membrane ring protein;
421-703 2.72e-06

EscC/YscC/HrcC family type III secretion system outer membrane ring protein;


Pssm-ID: 237948 [Multi-domain]  Cd Length: 559  Bit Score: 50.54  E-value: 2.72e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233  421 TNSIIAYQPQERLDELRRIVSQLDIPVRQVMIEARIVEANVGYDKSLGVrwggayhkgNWSGygkdgNIGIKDEDGmncg 500
Cdd:PRK15339 274 TNSLLVKGTAEQVHFIEMLVKALDVAKRHVELSLWIIDLDKSDLEQLGV---------NWSG-----SITIGDKLG---- 335

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233  501 piagsctfpttgtskspspfVDLGAKDATSGIGIGFITdniildlQLSAMEKTGNGEIVSQPKVVTSDKETAkILKGSEV 580
Cdd:PRK15339 336 --------------------VSLNQSSISTLDGSRFIA-------AVMALEQKKKANVVSRPVVLTQENIPA-IFDNNRT 387

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600233  581 PYQEASSSGATSTSFKEAALSLEVTPQITPDNRIIVEVKV---TKDAPDYQNMLN--GVPPINKNEVNAKILVNDGETIV 655
Cdd:PRK15339 388 FYTKLVGERNVALEHVTYGTMISVLPRFSADGQIEMSLDIedgNEKTPQSDTTTSvdALPEVGRTLISTIARVPQGKSLL 467

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 15600233  656 IGGVFSNEQSKSVEKVPFLGELPYLGRLFRRDTvTDRKNELLVFLT-PR 703
Cdd:PRK15339 468 IGGYTRDANTDEVQSIPFLGSLPLIGSLFRYSS-KNKSNIVRVFLIePR 515
STN smart00965
Secretin and TonB N terminus short domain; This is a short domain found at the N-terminus of ...
 306-354 5.43e-06

Secretin and TonB N terminus short domain; This is a short domain found at the N-terminus of the Secretins of the bacterial type II/III secretory system as well as the TonB-dependent receptor proteins. These proteins are involved in TonB-dependent active uptake of selective substrates.


Pssm-ID: 198033 [Multi-domain]  Cd Length: 52  Bit Score: 44.03  E-value: 5.43e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 15600233    306 LNLVASD-TVQG-NITLRLQNVPWDQALDLVLKTKGLDKRKL-GNVLLVAPA 354
Cdd:smart00965   1 LNFVYDPaLVAGrRVSLLLGNVTVEQALDRLLAGTGLTYRRIgGNTIVLSPA 52
STN pfam07660
Secretin and TonB N terminus short domain; This is a short domain found at the N-terminus of ...
 308-354 2.25e-05

Secretin and TonB N terminus short domain; This is a short domain found at the N-terminus of the Secretins of the bacterial type II/III secretory system as well as the TonB-dependent receptor proteins. These proteins are involved in TonB-dependent active uptake of selective substrates.


Pssm-ID: 429580 [Multi-domain]  Cd Length: 51  Bit Score: 42.12  E-value: 2.25e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 15600233   308 LVASDTVQGN--ITLRLQNVPWDQALDLVLKTKGLDKRKLGNVLLVAPA 354
Cdd:pfam07660   3 LYDSDLVDGKqsVSLNVGNVTLEEALDQLLAGTGLSYEIGGNTIVLRPK 51
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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