|
Name |
Accession |
Description |
Interval |
E-value |
| rep |
TIGR01074 |
ATP-dependent DNA helicase Rep; Designed to identify rep members of the uvrD/rep subfamily. ... |
3-664 |
0e+00 |
|
ATP-dependent DNA helicase Rep; Designed to identify rep members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 130146 [Multi-domain] Cd Length: 664 Bit Score: 1197.26 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 3 RLNPRQQEAVNYVGGPLLVLAGAGSGKTSVITRKIAYLVQQCGIRAQYIVAVTFTNKAAREMKERVGTLLRGGEGKGLTV 82
Cdd:TIGR01074 1 KLNPQQQEAVEYVTGPCLVLAGAGSGKTRVITNKIAYLIQNCGYKARNIAAVTFTNKAAREMKERVAKTLGKGEARGLTI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 83 STFHNLGLNIIRKEHERLGYKPGFSIFDESDIKALLTDIMQKEY-SGDDGVDEIKNYIGAWKNDLILPEEALEKARNPKE 161
Cdd:TIGR01074 81 STFHTLGLDIIKREYNALGYKSNFSLFDETDQLALLKELTEGLIkDDKDLLDKLISTISNWKNDLLTPEQALASARGERE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 162 QTAAIVYLHYQRTLRAYNAVDFDDLILQPVKLFQEHPDVLQKWQNKVRYMLVDEYQDTNASQYLLVKLLVKDRAQFTVVG 241
Cdd:TIGR01074 161 QTFAHCYALYQAHLRAYNALDFDDLILLPTLLLQQNEEVRNRWQNKIRYLLVDEYQDTNTSQYELVKLLVGDRARFTVVG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 242 DDDQSIYAWRGARPENLMQLKEDFPSLKVVMLEQNYRSTSRILKCANVLIANNPHVFEKQLWSEMGHGDPIRVIRCRNED 321
Cdd:TIGR01074 241 DDDQSIYSWRGARPENLVLLKEDFPQLKVIKLEQNYRSTGRILKAANILIANNPHVFEKKLFSELGYGEKIKVIECNNEE 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 322 AEAERIAMEILTLHLRTERPYSEFAILYRGNHQAKLMELKLQHHQIPYRLSGGTSFFGRQEVKDLMSYFRLLVNPDDDNA 401
Cdd:TIGR01074 321 HEAERIAGEIIAHKLVNKTQYKDYAILYRGNHQSRLLEKALMQNRIPYKLSGGTSFFSRPEIKDLLSYLRLLVNPDDDAA 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 402 FLRVINVPRREIGSATLEKLGNYATQRKISMYAACDEMGLAEHLDSRFHERLQRFKRWMDGIRRQCAENEPIAVLRSMVM 481
Cdd:TIGR01074 401 FLRIVNTPKREIGPATLEKLGELAMERNKSLFTASFDMGLLQTLSGRGYESLQRFTDWLVEIRRLAERSEPIEAVRSLIE 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 482 DIDYENWLRQNASSDKVAEFRMSNVWFLIEALKNTLERDEEGD-MTIEQAIAKLVLRDMLeRQQEEEEGAEGVQMMTLHA 560
Cdd:TIGR01074 481 DIDYENWLYETSPSPKAAEMRMKNVNTLFSWFKEMLEGDEEDEpMTLTQVVTRLTLRDML-ERGEDEEELDQVQLMTLHA 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 561 SKGLEFPYVFIMGMEEEILPHRSSIEADTVEEERRLAYVGITRARQNLAMTFAAKRKQYGEIIDCSPSRFLDELPPEDLE 640
Cdd:TIGR01074 560 SKGLEFPYVFIVGMEEGILPHQSSIEEDNVEEERRLAYVGITRAQKELTFTLCKERRQYGELVRPEPSRFLDELPQEDLQ 639
|
650 660
....*....|....*....|....*
gi 15600489 641 WEGMEDAP-QEVKAAKGNAALADIR 664
Cdd:TIGR01074 640 WEGDDPVVsAEEKMEKGQAHLANLR 664
|
|
| UvrD |
COG0210 |
Superfamily I DNA or RNA helicase [Replication, recombination and repair]; |
1-647 |
0e+00 |
|
Superfamily I DNA or RNA helicase [Replication, recombination and repair];
Pssm-ID: 439980 [Multi-domain] Cd Length: 721 Bit Score: 855.00 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 1 MSRLNPRQQEAVNYVGGPLLVLAGAGSGKTSVITRKIAYLVQQCGIRAQYIVAVTFTNKAAREMKERVGTLLrGGEGKGL 80
Cdd:COG0210 4 LAGLNPEQRAAVEHPEGPLLVLAGAGSGKTRVLTHRIAYLIAEGGVDPEQILAVTFTNKAAREMRERIEALL-GRLARGL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 81 TVSTFHNLGLNIIRKEHERLGYKPGFSIFDESDIKALLTDIMqKEYSGDDG---VDEIKNYIGAWKNDLILPEEALEK-A 156
Cdd:COG0210 83 WVGTFHSLALRILRRHAELLGLPPNFTILDGDDQLRLIKELL-KELGLDEKrfpPRELLSLISRAKNEGLTPEELAELlA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 157 RNPKEQTAAIVYLHYQRTLRAYNAVDFDDLILQPVKLFQEHPDVLQKWQNKVRYMLVDEYQDTNASQYLLVKLLVKDRAQ 236
Cdd:COG0210 162 ADPEWRAAAELYEAYQERLRANNALDFDDLLLLAVRLLEENPEVLEKYQNRFRYILVDEYQDTNPAQYELLRLLAGDGRN 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 237 FTVVGDDDQSIYAWRGARPENLMQLKEDFPSLKVVMLEQNYRSTSRILKCANVLIANNPHVFEKQLWSEMGHGDPIRVIR 316
Cdd:COG0210 242 LCVVGDDDQSIYGFRGADPENILRFEKDFPDAKVIKLEQNYRSTQNILDAANAVIANNPGRLGKNLWTDNGEGEKVRLYV 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 317 CRNEDAEAERIAMEILTLHlRTERPYSEFAILYRGNHQAKLMELKLQHHQIPYRLSGGTSFFGRQEVKDLMSYFRLLVNP 396
Cdd:COG0210 322 APDEEEEARFVADEIRELH-EEGVPLSDIAVLYRTNAQSRALEEALRRAGIPYRVVGGLRFYERAEIKDLLAYLRLLANP 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 397 DDDNAFLRVINVPRREIGSATLEKLGNYATQRKISMYAACDEMGLAEHLDSRFHERLQRFKRWMDGIRRQCAENEPIAVL 476
Cdd:COG0210 401 DDDVALLRILNVPRRGIGAATLERLREAAREEGISLLEALRDLGELAGLSGRAAKALRRFAELLEALRAAAERLPLEELL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 477 RSMVMDIDYENWLRQNASSDkvAEFRMSNVWFLIEALKNTLERDEEGdmTIEQAIAKLVLRDMLerqQEEEEGAEGVQMM 556
Cdd:COG0210 481 EALLDESGYEEELREEAGEE--AERRLENLEELVDAAARFEERNPGA--SLEAFLEELALLSDL---DAADEDEDAVTLM 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 557 TLHASKGLEFPYVFIMGMEEEILPHRSSI-EADTVEEERRLAYVGITRARQNLAMTFAAKRKQYGEIIDCSPSRFLDELP 635
Cdd:COG0210 554 TLHAAKGLEFPVVFLVGLEEGLFPHQRSLdDEEELEEERRLFYVAITRARERLYLTYAASRRLWGETQDNEPSRFLDELP 633
|
650
....*....|..
gi 15600489 636 PEDLEWEGMEDA 647
Cdd:COG0210 634 EELLEWVRPKAE 645
|
|
| PRK10919 |
PRK10919 |
ATP-dependent DNA helicase Rep; Provisional |
3-669 |
0e+00 |
|
ATP-dependent DNA helicase Rep; Provisional
Pssm-ID: 182838 [Multi-domain] Cd Length: 672 Bit Score: 849.51 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 3 RLNPRQQEAVNYVGGPLLVLAGAGSGKTSVITRKIAYLVQQCGIRAQYIVAVTFTNKAAREMKERVGTLLRGGEGKGLTV 82
Cdd:PRK10919 2 RLNPGQQQAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCGYQARHIAAVTFTNKAAREMKERVAQTLGRKEARGLMI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 83 STFHNLGLNIIRKEHERLGYKPGFSIFDESDIKALLTDIMQKEYSGD-DGVDEIKNYIGAWKNDLILPEEALEKARNPKE 161
Cdd:PRK10919 82 STFHTLGLDIIKREYAALGMKSNFSLFDDTDQLALLKELTEGLIEDDkVLLQQLISTISNWKNDLKTPAQAAAGAKGERD 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 162 QTAAIVYLHYQRTLRAYNAVDFDDLILQPVKLFQEHPDVLQKWQNKVRYMLVDEYQDTNASQYLLVKLLVKDRAQFTVVG 241
Cdd:PRK10919 162 RIFAHCYGLYDAHLKACNVLDFDDLILLPTLLLQRNEEVRERWQNKIRYLLVDEYQDTNTSQYELVKLLVGSRARFTVVG 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 242 DDDQSIYAWRGARPENLMQLKEDFPSLKVVMLEQNYRSTSRILKCANVLIANNPHVFEKQLWSEMGHGDPIRVIRCRNED 321
Cdd:PRK10919 242 DDDQSIYSWRGARPQNLVLLSQDFPALQVIKLEQNYRSSGRILKAANILIANNPHVFEKRLFSELGYGDELKVLSANNEE 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 322 AEAERIAMEILTLHLRTERPYSEFAILYRGNHQAKLMELKLQHHQIPYRLSGGTSFFGRQEVKDLMSYFRLLVNPDDDNA 401
Cdd:PRK10919 322 HEAERVTGELIAHHFVNKTQYKDYAILYRGNHQSRVFEKFLMQNRIPYKISGGTSFFSRPEIKDLLAYLRVLTNPDDDSA 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 402 FLRVINVPRREIGSATLEKLGNYATQRKISMYAACDEMGLAEHLDSRFHERLQRFKRWMDGIRRQcAENEPIAVLRSMVM 481
Cdd:PRK10919 402 FLRIVNTPKREIGPATLQKLGEWAMTRNKSLFTASFDMGLSQTLSGRGYESLTRFTHWLAEIQRL-AEREPVAAVRDLIH 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 482 DIDYENWLRQNASSDKVAEFRMSNVWFLIEALKNTLERDEEGD-MTIEQAIAKLVLRDMLeRQQEEEEGAEGVQMMTLHA 560
Cdd:PRK10919 481 GIDYESWLYETSPSPKAAEMRMKNVNQLFSWMTEMLEGSELDEpMTLTQVVTRFTLRDMM-ERGESEEELDQVQLMTLHA 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 561 SKGLEFPYVFIMGMEEEILPHRSSIEADTVEEERRLAYVGITRARQNLAMTFAAKRKQYGEIIDCSPSRFLDELPPEDLE 640
Cdd:PRK10919 560 SKGLEFPYVYLVGMEEGLLPHQSSIDEDNIDEERRLAYVGITRAQKELTFTLCKERRQYGELVRPEPSRFLLELPQDDLI 639
|
650 660 670
....*....|....*....|....*....|.
gi 15600489 641 WEGMED--APQEvKAAKGNAALADIRAMLKR 669
Cdd:PRK10919 640 WEQERKvvSAEE-RMQKGQSHLANLKAMLAA 669
|
|
| pcrA |
TIGR01073 |
ATP-dependent DNA helicase PcrA; Designed to identify pcrA members of the uvrD/rep subfamily. ... |
1-641 |
0e+00 |
|
ATP-dependent DNA helicase PcrA; Designed to identify pcrA members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273429 [Multi-domain] Cd Length: 726 Bit Score: 645.28 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 1 MSRLNPRQQEAVNYVGGPLLVLAGAGSGKTSVITRKIAYLVQQCGIRAQYIVAVTFTNKAAREMKERVGTLLrGGEGKGL 80
Cdd:TIGR01073 2 LAHLNPEQREAVKTTEGPLLIMAGAGSGKTRVLTHRIAHLIAEKNVAPWNILAITFTNKAAREMKERVEKLL-GPVAEDI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 81 TVSTFHNLGLNIIRKEHERLGYKPGFSIFDESDIKALLTDIMQKEysgddGVDE-------IKNYIGAWKNDLILPEEAL 153
Cdd:TIGR01073 81 WISTFHSMCVRILRRDIDRIGINRNFSIIDPTDQLSLMKTILKDK-----NLDPkkfeprsILGTISNAKNELLPPEDFA 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 154 EKARNPKEQTAAIVYLHYQRTLRAYNAVDFDDLILQPVKLFQEHPDVLQKWQNKVRYMLVDEYQDTNASQYLLVKLLVKD 233
Cdd:TIGR01073 156 KEATNYFEKVVAEVYQEYQKRLLRNNALDFDDLIMTTINLFQRVPDVLEYYQRKFQYIHVDEYQDTNRAQYTLVRLLASR 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 234 RAQFTVVGDDDQSIYAWRGARPENLMQLKEDFPSLKVVMLEQNYRSTSRILKCANVLIANNPHVFEKQLWSEMGHGDPIR 313
Cdd:TIGR01073 236 FRNLCVVGDADQSIYGWRGADIQNILSFEKDYPNATTILLEQNYRSTKNILQAANEVIEHNSNRKPKNLWTENSSGDKIT 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 314 VIRCRNEDAEAERIAMEILTLHLRTERPYSEFAILYRGNHQAKLMELKLQHHQIPYRLSGGTSFFGRQEVKDLMSYFRLL 393
Cdd:TIGR01073 316 YYEADTERDEAQFVAGEIDKLVKNGERKYGDFAILYRTNAQSRVFEETLLKANIPYKIVGGLKFYDRKEIKDILAYLRVI 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 394 VNPDDDNAFLRVINVPRREIGSATLEKLGNYATQRKISMYAACDEMGLAEHLDSRFHERLQRFKRWMDGIRRQCAENEPI 473
Cdd:TIGR01073 396 ANPDDDLSLLRIINVPKRGIGASSLEKIVNYALELNISLFEAIGEIDEIGGLAAKSANALLAFATMIENLRQQQEYLSPT 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 474 AVLRSMVMDIDYENWLRQNASSDkvAEFRMSNVWFLIEALKNTLERDEEGDMTIEQAIAKLVlrdMLERQQEEEEGAEGV 553
Cdd:TIGR01073 476 ELVEEVLDKSGYREMLKAEKTEE--AQSRLENLDEFLSVTKEFEDESEDKSLIDFLTDLALV---SDLDELEETEEGGAV 550
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 554 QMMTLHASKGLEFPYVFIMGMEEEILPH-RSSIEADTVEEERRLAYVGITRARQNLAMTFAAKRKQYGEIIDCSPSRFLD 632
Cdd:TIGR01073 551 TLMTLHAAKGLEFPVVFLIGMEEGVFPHsRSLMDEKELEEERRLAYVGITRAEEELYLTHATMRTLFGRIQMNPPSRFLN 630
|
....*....
gi 15600489 633 ELPPEDLEW 641
Cdd:TIGR01073 631 EIPAELLET 639
|
|
| uvrD |
PRK11773 |
DNA-dependent helicase II; Provisional |
4-640 |
5.13e-172 |
|
DNA-dependent helicase II; Provisional
Pssm-ID: 236976 [Multi-domain] Cd Length: 721 Bit Score: 508.26 E-value: 5.13e-172
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 4 LNPRQQEAVNYVGGPLLVLAGAGSGKTSVITRKIAYLVQQCGIRAQYIVAVTFTNKAAREMKERVGTLLRGGEGkGLTVS 83
Cdd:PRK11773 10 LNDKQREAVAAPLGNMLVLAGAGSGKTRVLVHRIAWLMQVENASPYSIMAVTFTNKAAAEMRHRIEQLLGTSQG-GMWVG 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 84 TFHNLGLNIIRKEHERLGYKPGFSIFDESDIKALLTDIMqKEYSGDDG---VDEIKNYIGAWKNDLILPEEaLEKARNPK 160
Cdd:PRK11773 89 TFHGLAHRLLRAHWQDANLPQDFQILDSDDQLRLLKRLI-KALNLDEKqwpPRQAQWYINGQKDEGLRPQH-IQSYGDPV 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 161 EQTAAIVYLHYQRTLRAYNAVDFDDLILQPVKLFQEHPDVLQKWQNKVRYMLVDEYQDTNASQYLLVKLLVKDRAQFTVV 240
Cdd:PRK11773 167 EQTWLKIYQAYQEACDRAGLVDFAELLLRAHELWLNKPHILQHYQERFTHILVDEFQDTNAIQYAWIRLLAGDTGKVMIV 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 241 GDDDQSIYAWRGARPENLMQLKEDFPSLKVVMLEQNYRSTSRILKCANVLIANNPHVFEKQLWSEMGHGDPIRVIRCRNE 320
Cdd:PRK11773 247 GDDDQSIYGWRGAQVENIQRFLNDFPGAETIRLEQNYRSTANILKAANALIANNNGRLGKELWTDGGDGEPISLYCAFNE 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 321 DAEA----ERIAMEiltlhLRTERPYSEFAILYRGNHQAKLMELKLQHHQIPYRLSGGTSFFGRQEVKDLMSYFRLLVNP 396
Cdd:PRK11773 327 LDEArfvvERIKTW-----QDNGGALSDCAILYRSNAQSRVLEEALLQAGIPYRIYGGMRFFERQEIKDALAYLRLIANR 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 397 DDDNAFLRVINVPRREIGSATLEKLGNYATQRKISMYAACDEMGLAEHLDSRFHERLQRFKRWMDGIRRQCAENePIAVL 476
Cdd:PRK11773 402 NDDAAFERVVNTPTRGIGDRTLDVVRQTARDRQLTLWQACRALLQEKVLAGRAASALQRFIELIDALAQETADM-PLHEQ 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 477 RSMVMDID--YENWlrQNASSDKvAEFRMSNVWFLIEALKNTLERDEEGDMTIEQAI---AKLVLRDMlerqqEEEEGAE 551
Cdd:PRK11773 481 TDRVIKDSglRAMY--EQEKGEK-GQARIENLEELVTATRQFSYPDEDEDLTPLQAFlshAALEAGEG-----QADAHED 552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 552 GVQMMTLHASKGLEFPYVFIMGMEEEILPHRSSI-EADTVEEERRLAYVGITRARQNLAMTFAAKRKQYGEIIDCSPSRF 630
Cdd:PRK11773 553 AVQLMTLHSAKGLEFPLVFIVGMEEGLFPSQMSLeEGGRLEEERRLAYVGITRAMQKLTLTYAESRRLYGKEVYHRPSRF 632
|
650
....*....|
gi 15600489 631 LDELPPEDLE 640
Cdd:PRK11773 633 IREIPEECVE 642
|
|
| uvrD |
TIGR01075 |
DNA helicase II; Designed to identify uvrD members of the uvrD/rep subfamily. [DNA metabolism, ... |
4-640 |
2.25e-162 |
|
DNA helicase II; Designed to identify uvrD members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 130147 [Multi-domain] Cd Length: 715 Bit Score: 483.54 E-value: 2.25e-162
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 4 LNPRQQEAVNYVGGPLLVLAGAGSGKTSVITRKIAYLVQQCGIRAQYIVAVTFTNKAAREMKERVGTLLRGGEGkGLTVS 83
Cdd:TIGR01075 5 LNDKQREAVAAPPGNLLVLAGAGSGKTRVLTHRIAWLLSVENASPHSIMAVTFTNKAAAEMRHRIGALLGTSAR-GMWIG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 84 TFHNLGLNIIRKEHERLGYKPGFSIFDESDIKALLTDIMQKEysgddGVDE-------IKNYIGAWKNDLILPEEaLEKA 156
Cdd:TIGR01075 84 TFHGLAHRLLRAHHLDAGLPQDFQILDSDDQLRLLKRLIKAL-----NLDEkqwpprqAMWYINNQKDEGLRPSH-IQAF 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 157 RNPKEQTAAIVYLHYQRTLRAYNAVDFDDLILQPVKLFQEHPDVLQKWQNKVRYMLVDEYQDTNASQYLLVKLLVKDRAQ 236
Cdd:TIGR01075 158 DNPVERTWIKIYQAYQEACDRAGLVDFAELLLRAHELLRNKPHILQHYQERFTHILVDEFQDTNKIQYAWIRLLAGNTGN 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 237 FTVVGDDDQSIYAWRGARPENLMQLKEDFPSLKVVMLEQNYRSTSRILKCANVLIANNPHVFEKQLWSEMGHGDPIRVIR 316
Cdd:TIGR01075 238 VMIVGDDDQSIYGWRGAQVENIQKFLKDFPGAETIRLEQNYRSTANILAAANALIANNDERLGKNLWTDGEVGEPISLYS 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 317 CRNEDAEAERIAMEILTLHlRTERPYSEFAILYRGNHQAKLMELKLQHHQIPYRLSGGTSFFGRQEVKDLMSYFRLLVNP 396
Cdd:TIGR01075 318 AFNELDEARFVVSRIKTWQ-RNGGALDECAVLYRSNAQSRVLEEALLQASIPYRIYGGMRFFERQEIKDALAYLRLIANR 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 397 DDDNAFLRVINVPRREIGSATLEKLGNYATQRKISMYAACDEMGLAEHLDSRFHERLQRFKRWMDGIRRQCAENEPIAVL 476
Cdd:TIGR01075 397 NDDAAFERVINTPTRGIGDRTLDVVRQAARDRGLTLWQAARELTQEKVLAGRAASALQRFVELIEALANETADMPLHVQT 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 477 RSMVMDIDYENWLRQNASSDkvAEFRMSNVWFLIEALKNTLERDEEGDMTIEQAIakLVLRDMLERQQEEEEGAEGVQMM 556
Cdd:TIGR01075 477 DHVIKDSGLREMYQQEKGEK--GQARIENLEELVTATRQFSLPENDEDMTPLTAF--LSHAALEAGEGQADAGQDAVQLM 552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 557 TLHASKGLEFPYVFIMGMEEEILP-HRSSIEADTVEEERRLAYVGITRARQNLAMTFAAKRKQYGEIIDCSPSRFLDELP 635
Cdd:TIGR01075 553 TLHSAKGLEFPLVFLVGMEEGMFPsQMSLDEGGRLEEERRLAYVGITRAMQKLTITYAETRRLYGKEVYHIPSRFIRELP 632
|
....*
gi 15600489 636 PEDLE 640
Cdd:TIGR01075 633 EECLH 637
|
|
| UvrD-helicase |
pfam00580 |
UvrD/REP helicase N-terminal domain; The Rep family helicases are composed of four structural ... |
4-266 |
6.52e-111 |
|
UvrD/REP helicase N-terminal domain; The Rep family helicases are composed of four structural domains. The Rep family function as dimers. REP helicases catalyze ATP dependent unwinding of double stranded DNA to single stranded DNA. Swiss:P23478, Swiss:P08394 have large insertions near to the carboxy-terminus relative to other members of the family.
Pssm-ID: 395462 [Multi-domain] Cd Length: 267 Bit Score: 334.98 E-value: 6.52e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 4 LNPRQQEAVNYVGGPLLVLAGAGSGKTSVITRKIAYLVQQCGIRAQYIVAVTFTNKAAREMKERVGTLLRGGEGKGLTVS 83
Cdd:pfam00580 1 LNPEQRKAVTHLGGPLLVLAGAGSGKTRVLTERIAYLILEGGIDPEEILAVTFTNKAAREMKERILKLLGKAELSELNIS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 84 TFHNLGLNIIRKEHERLGYKPGFSIFDESDIKALLTDIMQKEYSGDD----GVDEIKNYIGAWKNDLILPEEALEKARNP 159
Cdd:pfam00580 81 TFHSFCLRILRKYANRIGLLPNFSILDELDQLALLKELLEKDRLNLDpkllRKLELKELISKAKNRLLSPEELQQGAADP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 160 KEQTAAIVYLHYQRTLRAYNAVDFDDLILQPVKLFQEHPDVLQKWQNKVRYMLVDEYQDTNASQYLLVKLLVKDRAQFTV 239
Cdd:pfam00580 161 RDKLAAEFYQEYQERLKENNALDFDDLLLLTLELLRSDPELLEAYRERFKYILVDEFQDTNPIQYRLLKLLAGGHENLFL 240
|
250 260
....*....|....*....|....*..
gi 15600489 240 VGDDDQSIYAWRGARPENLMQLKEDFP 266
Cdd:pfam00580 241 VGDPDQSIYGFRGADIENILKFEKDFP 267
|
|
| RecB |
COG1074 |
3#-5# helicase subunit RecB of the DNA repair enzyme RecBCD (exonuclease V) [Replication, ... |
1-618 |
9.82e-88 |
|
3#-5# helicase subunit RecB of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];
Pssm-ID: 440692 [Multi-domain] Cd Length: 866 Bit Score: 292.64 E-value: 9.82e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 1 MSRLNPRQQEAVNYVGGPLLVLAGAGSGKTSVITRKIAYLVQQCGIRAQYIVAVTFTNKAAREMKERVGTLLRGGEGK-- 78
Cdd:COG1074 3 EPPWTDAQRRALDPLGGSVLVEASAGSGKTYTLVARYLRLLLERGLDPEEILVVTFTRAAAAEMRERIRERLAEAADLed 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 79 ---------------------GLTVSTFHNLGLNIIRKEHERLGYKPGFSIFDESD---IKALLTDIMQKEYSGDDGV-- 132
Cdd:COG1074 83 pdleelararrrlaralenldRAAISTIHSFCQRLLREFAFEAGLDPNFELLDDAEallLEEAVDDLLREAYAPLDALal 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 133 -----------DEIKNYIGAW-----------------------KNDLILPEEALEKARNPKEQTAA-----------IV 167
Cdd:COG1074 163 arlldafgrddDSLEELLLALyklrsrpdwleelaeldealealREALLKAKEALAALREALAAAAApllaallrllaAV 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 168 YLHYQRTLRAYNAVDFDDLILQPVKLFQEH--PDVLQKWQNKVRYMLVDEYQDTNASQYLLVKLLVKDRAQ----FTVVG 241
Cdd:COG1074 243 LARYERRKRERGLLDFDDLLHRALRLLRDEdaPWVAERLRERYRHILVDEFQDTSPLQWEILRRLAGEALAdgrtLFLVG 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 242 DDDQSIYAWRGARPENLMQLKEDF---PSLKVVMLEQNYRSTSRILKCANvliannpHVFEKQLWSEM------------ 306
Cdd:COG1074 323 DPKQSIYRFRGADPELFLEARRALegrVDGERLTLTTNFRSTPEVVDAVN-------ALFAQLMGAGFgeipyepvealr 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 307 -GHGDPIRVIRCRNED--------AEAERIAMEILTLH------LRTERP--YSEFAILYRGNHQAKLMELKLQHHQIPY 369
Cdd:COG1074 396 pGAYPAVELWPLEPDDvseedareREARAVAARIRRLLaegttvEGGGRPvrPGDIAVLVRTRSEAAAIARALKAAGIPV 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 370 RLSGGTSFFGRQEVKDLMSYFRLLVNPDDDNAFLRVInvpRREIGSATLEKLGNYATQRKismyaacdEMGLAEHLdsRF 449
Cdd:COG1074 476 AASDRLSLFESPEVRDLLALLRALLNPEDDLALAAVL---RSPLFGLSDEDLAALAADRK--------GESLWEAL--RA 542
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 450 HERLQRFKRWMDGIRRQCAENEPIAVLRSMVMDIDYENWLRQNASsdkvAEFRMSNVWFLIEALKNTLERDEEGDMTIE- 528
Cdd:COG1074 543 YERLARALERLRALRELARRLGLAELLERLLEETGLLERLLALPG----GERRLANLLHLDELLQLALEYEQTGGPGLAg 618
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 529 --QAIAKLVLRDMLERQQEEEEGAEGVQMMTLHASKGLEFPYVFIMGMEEEilphrssIEADTVEEERRLAYVGITRARQ 606
Cdd:COG1074 619 flRWLERLIEDGGDEEKRRLESDADAVRIMTIHKSKGLEFPVVFLPALRER-------ARAEELAEELRLLYVALTRARD 691
|
730
....*....|..
gi 15600489 607 NLAMTFAAKRKQ 618
Cdd:COG1074 692 RLVLSGAVKKKD 703
|
|
| DEXQc_UvrD |
cd17932 |
DEXQD-box helicase domain of UvrD; UvrD is a highly conserved helicase involved in mismatch ... |
5-277 |
3.48e-84 |
|
DEXQD-box helicase domain of UvrD; UvrD is a highly conserved helicase involved in mismatch repair, nucleotide excision repair, and recombinational repair. It plays a critical role in maintaining genomic stability and facilitating DNA lesion repair in many prokaryotic species including Helicobacter pylori and Escherichia coli. UvrD is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350690 [Multi-domain] Cd Length: 189 Bit Score: 262.84 E-value: 3.48e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 5 NPRQQEAVNYVGGPLLVLAGAGSGKTSVITRKIAYLVQQCGIRAQYIVAVTFTNKAAREMKERVGTLLRGGEGKGLTVST 84
Cdd:cd17932 1 NPEQREAVTHPDGPLLVLAGAGSGKTRVLTHRIAYLILEGGVPPERILAVTFTNKAAKEMRERLRKLLGEQLASGVWIGT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 85 FHNLGLNIIRKEHerlgykpgfsifdesdikalltdimqkeysgddgvdeiknyigawkndlilpeealekarnpkeqta 164
Cdd:cd17932 81 FHSFALRILRRYG------------------------------------------------------------------- 93
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 165 aivylhyqrtlraynavDFDDLILQPVKLFQEHPDVLQKWQNKVRYMLVDEYQDTNASQYLLVKLLVKDRAQFTVVGDDD 244
Cdd:cd17932 94 -----------------DFDDLLLYALELLEENPDVREKLQSRFRYILVDEYQDTNPLQYELLKLLAGDGKNLFVVGDDD 156
|
250 260 270
....*....|....*....|....*....|...
gi 15600489 245 QSIYAWRGARPENLMQLKEDFPSLKVVMLEQNY 277
Cdd:cd17932 157 QSIYGFRGADPENILDFEKDFPDAKVIKLEENY 189
|
|
| UvrD_C |
pfam13361 |
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety ... |
271-613 |
7.25e-65 |
|
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety of helicase enzymes. This domain has a AAA-like structural fold.
Pssm-ID: 433145 [Multi-domain] Cd Length: 377 Bit Score: 218.81 E-value: 7.25e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 271 VMLEQNYRSTSRILKCANVLIANNPHV----FEKQLWSEMGHGDPIRVIRCRNEDAEAERIAMEILTLhLRTERPYSEFA 346
Cdd:pfam13361 1 IHLEINYRSTKNLLKAANEFINNNFGRatiyPKKILAETVEDGEKIKIIEAETEEEEAEWIALEIKKL-VARDEKYNDIA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 347 ILYRGNHQAKLMELKLQHHQIPYRLSGGTSFFGRQEVKDLMSYFRLLVNPDDDNAFLRVINVPRREIGSATLEKLGNYAT 426
Cdd:pfam13361 80 VLTRSNSDADLIEEALKKLGIPYFVVGQTKFFRREEIKDILAYLRLIANKHDSISLKRILNGPKRGIGNATLERIREYKK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 427 -----QRKISMYAACDEMGLAEHLDSRFH--------------------------------ERLQRFKRW---------- 459
Cdd:pfam13361 160 rglrlSDFINPDTLTYGDPFVIALEQDNIvvfdvettgldttedeiiqiaaiklnkkgvviESFERFLRLkkpvgdslqv 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 460 --MDGIRRQCAENEPIAVLRSMVMDI-----------DYENWLRQNASSDKVAEFrmsnvwflieaLK-NTLERDEEGDM 525
Cdd:pfam13361 240 hgFSDEFLQENGETPAEALRDFLEKLenlrelysilrEYDDIEETPEPEDALRNF-----------LEiATLSNSELEGS 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 526 TIEQAIaklvlrdmlerqqeeeegaegvQMMTLHASKGLEFPYVFIMGMEEEILPH-RSSIEADTVEEERRLAYVGITRA 604
Cdd:pfam13361 309 DIKERI----------------------PIMTIHQAKGLEFDTVFLAGLEEGIFPSyRSIKDEGNLEEERRLFYVAITRA 366
|
....*....
gi 15600489 605 RQNLAMTFA 613
Cdd:pfam13361 367 KKRLYISYS 375
|
|
| helD |
PRK11054 |
DNA helicase IV; Provisional |
2-304 |
6.87e-30 |
|
DNA helicase IV; Provisional
Pssm-ID: 182930 [Multi-domain] Cd Length: 684 Bit Score: 125.45 E-value: 6.87e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 2 SRLNPRQQEAVnyVGGP--LLVLAGAGSGKTSVITRKIAYLVQQCGIRAQYIVAVTFTNKAAREMKER----VGTllrgg 75
Cdd:PRK11054 195 SPLNPSQARAV--VNGEdsLLVLAGAGSGKTSVLVARAGWLLARGQAQPEQILLLAFGRQAAEEMDERirerLGT----- 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 76 egKGLTVSTFHNLGLNIIRK-EHERlgykPGFSIFdESDIKA---LLTDIMQKEYSgddgvdEIKNYIGAWKNDLI---- 147
Cdd:PRK11054 268 --EDITARTFHALALHIIQQgSKKV----PVISKL-ENDSKArhaLLIAEWRKQCS------EKKAQAKGWRQWLTeelq 334
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 148 --LPEEalEKARNPK---------EQTAAIVYLH--------------------------------YQRTLRAYNAVDFD 184
Cdd:PRK11054 335 wdVPEG--NFWDDEKlqrrlasrlERWVSLMRMHggsqaemiaqapeevrdlfqkrlklmapllkaWKKALKAENAVDFS 412
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 185 DLILQPVklfqehpDVLQK------WqnkvRYMLVDEYQDTNASQYLLVKLLVKDRAQFTV--VGDDDQSIYAWRGARPE 256
Cdd:PRK11054 413 GLIHQAV-------NYLEKgrfispW----KHILVDEFQDISPQRAALLAALRKQNSQTTLfaVGDDWQAIYRFSGADLS 481
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 15600489 257 NLMQLKEDFPSLKVVMLEQNYRSTSRILKCANVLIANNPHVFEKQLWS 304
Cdd:PRK11054 482 LTTAFHERFGEGDRCHLDTTYRFNSRIGEVANRFIQQNPHQLKKPLNS 529
|
|
| addA_Gpos |
TIGR02785 |
helicase-exonuclease AddAB, AddA subunit, Firmicutes type; AddAB, also called RexAB, ... |
6-608 |
3.66e-28 |
|
helicase-exonuclease AddAB, AddA subunit, Firmicutes type; AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the Firmicutes (as modeled here) and the alphaproteobacteria, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 274299 [Multi-domain] Cd Length: 1230 Bit Score: 121.35 E-value: 3.66e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 6 PRQQEAVNYVGGPLLVLAGAGSGKTSVITRKIAYLVQQcGIRAQYIVAVTFTNKAAREMKERVGT-----LLRGGEGKGL 80
Cdd:TIGR02785 4 DEQWQAIYTRGQDILVSASAGSGKTAVLVERIIRKITR-GVDVDRLLVVTFTNAAAREMKERIAEalekeLVQEPNSKHL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 81 ----------TVSTFHNLGLNIIRKEHERLGYKPGFSIFDESD----IKALLTDIMQKEYSGDD--GVDEI-KNYIG--- 140
Cdd:TIGR02785 83 rrqlallntaNISTLHSFCLKVIRKHYYLLDLDPSFRILTDTEqlllIKEVLDDVFEEEYYKEDkeAFFELvDNFSGdrs 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 141 ----------------------AWKNDLILP---------------------------------EEALEK---------- 155
Cdd:TIGR02785 163 ddglrdlilqlydfsrstpnpeKWLNNLAEAyevkekftieslklqqqikellkneleglqeklQRALELfmaedglapr 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 156 --------------------------------------------------------------------------ARNPKE 161
Cdd:TIGR02785 243 lenfqldlqnideliqeslaqadwnelrkavaafkfknlkaakgdeedadlleeadklreeakkqleklktdyfTRSEED 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 162 QTAAIVYLH----------------YQRTLRAYNAVDFDDL---ILQPVKLFQEHPD-VLQKWQNKVRYMLVDEYQDTNA 221
Cdd:TIGR02785 323 HLRIMQEMKpvvktlvqlvkdfierFGAEKREKNILDFSDLehyALQILTNENESPSeAAEFYREKFHEVLVDEYQDTNL 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 222 SQYLLVKLLVKDRAQFT---VVGDDDQSIYAWRGARPENLMQLKEDFPSL-----KVVMLEQNYRSTSRILKCANVLI-- 291
Cdd:TIGR02785 403 VQESILQLVKRGPEEEGnlfMVGDVKQSIYRFRQADPLLFLEKYHRFAQEgeehgKRIDLAENFRSRAEVLDTTNFLFkq 482
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 292 ------------------------------ANNPHVFEKQLW--SEMGHGDPIRVIRCRNEdAEAERIAMEILTL----- 334
Cdd:TIGR02785 483 lmdeevgeidydeeaqlkfgaakypenpdnKTEELLYEKLLIeeAEEEEIDEEAEILDKAQ-QEATMVAERIKALikegf 561
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 335 -----HLRTERP--YSEFAILYRGNHQAKLMELKLQHHQIPYRLSGGTSFFGRQEVKDLMSYFRLLVNPDDDNAFLRVIN 407
Cdd:TIGR02785 562 kvydkKTGTYRPvtYRDIVILTRSRGWNLQIMEEFKKYGIPVFANDAENYFQTTEVRVMLSLLRVIDNPYQDIPLVAVLR 641
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 408 VPrreIGSATLEKLGNYATQRKIS-MYAACDEMGLAEHLDSRFHERLQRFKRWMDGIRRQcAENEPIAVLRSMVMD---- 482
Cdd:TIGR02785 642 SP---IVGFDENELALIRLENKDSsYYEAVKDYVKAGLIEDELYEKLNTFLDSLQKWREF-ARTHSVSELIWKIYNdtgy 717
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 483 IDYENWL-----RQ---NASSDKVAEFRMSNVWFLIEALkNTLERDEEGDMTIEQAIAklvlrdmlerqqeEEEGAEGVQ 554
Cdd:TIGR02785 718 YDYVGGLpggkqRQanlYALYERARQYESTSFKGLFQFI-RFIERMQERQKDLASAVA-------------VGEAENAVR 783
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 555 MMTLHASKGLEFPYVFIMGME---------EEILPHRSS--------------------------IEADTVEEERRLAYV 599
Cdd:TIGR02785 784 LMTIHKSKGLEFPVVFVLGMGkqfnkqdlnSSYLLDRQLglgikyidpqerlsypslpkvaikqkMKRELLSEEMRVLYV 863
|
....*....
gi 15600489 600 GITRARQNL 608
Cdd:TIGR02785 864 ALTRAKEKL 872
|
|
| AddB |
COG3857 |
ATP-dependent helicase/DNAse subunit B [Replication, recombination and repair]; |
20-669 |
1.69e-24 |
|
ATP-dependent helicase/DNAse subunit B [Replication, recombination and repair];
Pssm-ID: 443066 [Multi-domain] Cd Length: 1019 Bit Score: 109.45 E-value: 1.69e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 20 LVLAGAGSGKTSVITRKIAYLVQQcGIRAQYIVAVTFTnkaaREMKERVGTLLRGGEGKGLTVSTFHNLGLNIIRkehER 99
Cdd:COG3857 2 FILGRAGSGKTTYLLEEIKEELKE-GKPIILLVPEQMT----FQAERALLKRLGLGGSIRAQVLSFSRLAWRVLQ---ET 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 100 LGYKPgfSIFDESDIKALLTDIMQKE---------YSGDDG-VDEIKNYIGAWKNDLILPEEALEKARNPKEQTA--AIV 167
Cdd:COG3857 74 GGATR--PLLSDAGKRMLLRKILEEHkdelkvfarAADKPGfIEQLAELITELKRYGITPEDLEEAAELLKEKLRdlALI 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 168 YLHYQRTLRAYNaVDFDDLIlqpvKLFQEHPDVLQKWQNKVRYmlVDEYQDTNASQYLLVKLLVKDRAQFTVVGDDDQSI 247
Cdd:COG3857 152 YEAYEEKLAGRY-IDSEDLL----RLLAEKLEKSEFLEGAEIY--IDGFTDFTPQELELLEALLKKAKEVTITLTLDPDE 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 248 YAWRGARPENLMQLKEDFPSLKVvmlEQNYRSTSRILKCANVLIANNPHvfekqlwsemGHGDPIRVIRCRNEDAEAERI 327
Cdd:COG3857 225 LDLFSATGETYERLLELAKENGV---EVEFKKSPELAHLERNLFAYPPE----------EEPEGIEIIEAANRRAEVEAV 291
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 328 AMEILTLHLRTERPYSEFAILYRG-NHQAKLMELKLQHHQIPYRLSGGTSFFGRQEVKDLMSYFRLLVNPDDDNAFLRVI 406
Cdd:COG3857 292 AREIRRLVREEGYRYRDIAVVVRDlEAYAPLIERVFAEYGIPYFIDEKRPLSHHPLVELILSLLELVRSNFRYEDVFRLL 371
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 407 ------NVPRREIgsatlEKLGNYATQRKISMYA----ACDEMGLAEHLDSRFHERLQRFKR----WMDGIRRQCAENEP 472
Cdd:COG3857 372 ktgllrPLSREEI-----DRLENYVLAYGIRGRRwlerYLEEEEELTDEEEEDLERLNELRDrllePLLPLRERLKKAKT 446
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 473 IA----VLRSMVMDIDYENWLRQNASSDKVAEFRMSN----VWF-LIEALKNTLERDEEGDMTIEQAIAklVLRDMLERQ 543
Cdd:COG3857 447 VRewaeALYEFLEELGVPEKLEEWREAEEAGDLEEAReheqAWNaLIELLDELVEVLGDEKLSLEEFLR--ILESGLEEL 524
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 544 QEEE--EGAEGVQMMTLHASKGLEFPYVFIMGMEEEILPHRSSIE----------------------ADTVEEERRLAYV 599
Cdd:COG3857 525 TFGLipPSLDQVQVGGLDRARGLDFKAVFVLGLNEGVFPARPREDgllsdeererlnelglelpptsRERLLEERFLFYR 604
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15600489 600 GITRARQNLAMTFAAKRKQYGEIidcSPSRFLDELPPEDLEWEGMEDAPQEVKA-AKGNAALADIRAMLKR 669
Cdd:COG3857 605 ALTRASERLYLSYPLADEEGKAL---LPSPLIDRLRELFPELEERSLLEEELEYiGTPESALSELAAALRQ 672
|
|
| SF1_C_UvrD |
cd18807 |
C-terminal helicase domain of UvrD family helicases; UvrD is a highly conserved helicase ... |
279-611 |
4.86e-24 |
|
C-terminal helicase domain of UvrD family helicases; UvrD is a highly conserved helicase involved in mismatch repair, nucleotide excision repair, and recombinational repair. It plays a critical role in maintaining genomic stability and facilitating DNA lesion repair in many prokaryotic species including Helicobacter pylori and Escherichia coli. This family also includes ATP-dependent helicase/nuclease AddA and helicase/nuclease RecBCD subunit RecB, among others. UvrD family helicases are DEAD-like helicases belonging to superfamily (SF)1, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF2 helicases, SF1 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350194 [Multi-domain] Cd Length: 150 Bit Score: 98.46 E-value: 4.86e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 279 STSRILKCANVLIANNPHVFEKQLWSEMGHGDPIRVIRCRNEDAEAERIAMEILTLHLRTERPYSEFAILYRGNHQAKLM 358
Cdd:cd18807 1 STKNILDAANSLIKQNKNRPKKPLKAGNKSGGPVELLLAKDEADEAKAIADEIKRLIESGPVQYSDIAILVRTNRQARVI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 359 Elklqhhqipyrlsggtsffgrqevkdlmsyfrllvnpdddnaflrvinvprreigsatleklgnyatqrkismyaacde 438
Cdd:cd18807 81 E------------------------------------------------------------------------------- 81
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 439 mglaehldsrfherlqrfkrwmdgirrqcaenepiavlrsmvmdidyenwlrqnassdkvaefrmsnvwfliEALKntle 518
Cdd:cd18807 82 ------------------------------------------------------------------------EALR---- 85
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 519 rdeegdmtieqaiaklvlrdmlerqqeeeegaegVQMMTLHASKGLEFPYVFIMGMEEEILPHRSSIEA-----DTVEEE 593
Cdd:cd18807 86 ----------------------------------VTLMTIHASKGLEFPVVFIVGLGEGFIPSDASYHAakedeERLEEE 131
|
330
....*....|....*...
gi 15600489 594 RRLAYVGITRARQNLAMT 611
Cdd:cd18807 132 RRLLYVALTRAKKELYLV 149
|
|
| addA_alphas |
TIGR02784 |
double-strand break repair helicase AddA, alphaproteobacterial type; AddAB, also called RexAB, ... |
171-608 |
9.77e-22 |
|
double-strand break repair helicase AddA, alphaproteobacterial type; AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the alphaproteobacteria (as modeled here) and the Firmicutes, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 274298 [Multi-domain] Cd Length: 1135 Bit Score: 100.53 E-value: 9.77e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 171 YQRTLRAYNAVDFDDLILQPVKLFQEhPD----VLQKWQNKVRYMLVDEYQDTNASQYLLVKLLV---------KDRAQF 237
Cdd:TIGR02784 351 YARLKKARGLLDFNDLIERTVALLAR-PGagawVHYKLDRGIDHILVDEAQDTSPEQWDIIQALAeeffsgegaRSGVER 429
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 238 T--VVGDDDQSIYAWRGARPENLMQLKEDFPS--------LKVVMLEQNYRSTSRILKCANVLIANN------PHVFEKQ 301
Cdd:TIGR02784 430 TifAVGDEKQSIYSFQGADPERFAEERREFSRkvravgrkFEDLSLNYSFRSTPDVLAAVDLVFADPenarglSADSDAP 509
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 302 LWSEMGHGDPIRVI---RCRNEDAE---------------------AERIAMEILTLHLRTE------RP--YSEFAILY 349
Cdd:TIGR02784 510 VHEAFRDDLPGRVDlwdLISKEEGEepedwtdpvdelgerapevrlAERIAAEIRAWLDRGTpipgrgRAvrPGDILVLV 589
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 350 RG-NHQAKLMELKLQHHQIPY----RLSGGtsffGRQEVKDLMSYFRLLVNPDDDNAFLRVINVPRREIGSATLEKLGny 424
Cdd:TIGR02784 590 RKrDAFFSALIRALKRRGIPVagadRLKLT----SHIAVKDLMALGRFVLQPEDDLSLAALLKSPLFGLDEDDLFRLA-- 663
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 425 ATQRKISMYAAcdemgLAEHlDSRFHERLQRFKRWMDGIRRqcaenEPIAVLRSMVMDIDYEnwlRQ-------NASSDK 497
Cdd:TIGR02784 664 AGRSGGSLWAA-----LRRR-EAEFAATLAVLRDWLSLADF-----LTPFEFYARLLGRDGG---RRkllarlgAEAEDI 729
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 498 VAEfrmsnvwFLIEALknTLERDE----EGDMTIEQAIAKLVLRDMlerqqeeEEGAEGVQMMTLHASKGLEFPYVFIM- 572
Cdd:TIGR02784 730 LDE-------FLSQAL--AYERTGlpglQAFLSWLEADDPEIKREM-------DQARDEVRVMTVHGAKGLEAPVVFLVd 793
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15600489 573 ------------------GMEEEILPHRSSIEADT--------------VEEERRLAYVGITRARQNL 608
Cdd:TIGR02784 794 tgskpfasqraplllatgGSGGKAPLWRPASAFDPslsaaarerlkeraEDEYRRLLYVAMTRAEDRL 861
|
|
| PRK13909 |
PRK13909 |
RecB-like helicase; |
23-608 |
3.72e-18 |
|
RecB-like helicase;
Pssm-ID: 237554 [Multi-domain] Cd Length: 910 Bit Score: 88.87 E-value: 3.72e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 23 AGAGSGKTSVIT-RKIAYLVQqcGIRAQYIVAVTFTNKAAREMKERV-GTLLRGGEGKG--------------------- 79
Cdd:PRK13909 5 ASAGSGKTFALSvRFLALLFK--GANPSEILALTFTKKAANEMKERIiDTLLNLEKEKEeselneleeklglskeellnk 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 80 ------------LTVSTFHNLGLNIIRKEHERLGYKPGFSIFDES---------------DIKALLTDIMQKEYSGDDGV 132
Cdd:PRK13909 83 rdkvyqeflnseLKISTIDAFFQKILRKFCLNLGLSPDFSIKEDTkeelnekflsalskeELLELLAFIKQCESKKNNSF 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 133 DEI-------KNYIGAWKNDLILP----EEALEKARNPKEQTAAIVYlHYQRTLRAYNAVDFDDLILQPV---------- 191
Cdd:PRK13909 163 FELleklyekNNELKLFEKAKNPIefdeEKFLEELRSLKQQIQSIET-ASKNAKKAFKKEDFEELLNSSKtwlekeseyr 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 192 ------------------------------KLFQEHPDVLQKWQN----------------------------------- 206
Cdd:PRK13909 242 yfkklyneeldaefeelknalkryydakenYKLSKLFKLLQLYKEaknelnkkknaldfddiskkvyellgeeeidkdfl 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 207 ------KVRYMLVDEYQDTNASQYLLVKLL---------VKDRAQFTVVGDDDQSIYAWRGARPENLMQLKEDFpSLKVV 271
Cdd:PRK13909 322 yfrldsKISHILIDEFQDTSVLQYKILLPLideiksgegQKKFRSFFYVGDVKQSIYRFRGGKKELFDKVSKDF-KQKVD 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 272 MLEQNYRSTSRILKCANVLIANNPHVFEKQLWSEMGHGDPIRVIRCRNEDAE-AERIAMEILTLhLRTERPYSEFAILYR 350
Cdd:PRK13909 401 NLDTNYRSAPLIVDFVNEVFKKKYKNYKTQYAEQHKSGGYVEVVEVADESEElLEQLLQEIQFL-LEKGIDPDDIAILCW 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 351 GNHQAKLMELKLQ-HHQIPYRLSGGTSFFGRQEVKDLMSYFRLLVNPDddnaflrvinvprrEIGSATLEKLGNYATQRK 429
Cdd:PRK13909 480 TNDDALEIKEFLQeQFGIKAVTESSAKLINQPEVKALIEALKYCLFGE--------------EIYKHNVLKLLGKEPDKI 545
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 430 ISMYAAcdEMGLAEHLdsrfHERLQRFKRWMDGIRRqCAEnepIAVlrsmvmdiDYENwlrqnassdkVAEFrmsnvwfl 509
Cdd:PRK13909 546 PSFLPK--EESVAEFV----KKLIEELKLYDENLLK-FLE---LAS--------GYED----------IEEF-------- 589
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 510 iealkntLERDEEGDMTIEQAIAKlvlrdmlerqqeeeegaeGVQMMTLHASKGLEFPYVFIM----------------- 572
Cdd:PRK13909 590 -------LFKLEPCDKEIASEESK------------------GVQIMTVHKSKGLEFEHVIVCdrlgkpnsdssnllfey 644
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|..
gi 15600489 573 -GMEEEILPHRSS---------------IEADTVEEERRLAYVGITRARQNL 608
Cdd:PRK13909 645 dGIELWQIYYRIKgrenfdkdyaralekEKALKYEEEINVLYVAFTRAKNSL 696
|
|
| AAA_19 |
pfam13245 |
AAA domain; |
8-251 |
2.09e-14 |
|
AAA domain;
Pssm-ID: 433059 [Multi-domain] Cd Length: 136 Bit Score: 70.32 E-value: 2.09e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 8 QQEAVNY--VGGPLLVLAGAGSGKTSVITRKIAYLVQQCGIRAQyIVAVTFTNKAAREMKERVgtllrggegkGLTVSTF 85
Cdd:pfam13245 1 QREAVRTalPSKVVLLTGGPGTGKTTTIRHIVALLVALGGVSFP-ILLAAPTGRAAKRLSERT----------GLPASTI 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 86 HNLglniirkeherLGYKPGfsifdesdikalltdimqkeysgddgvdeiknyigawkndlilpeEALEKARNPKEqtaa 165
Cdd:pfam13245 70 HRL-----------LGFDDL---------------------------------------------EAGGFLRDEEE---- 89
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 166 ivylhyqrtlraynavdfddlilqpvklfQEHPDVLqkwqnkvrymLVDEYQDTNA-SQYLLVKLLvKDRAQFTVVGDDD 244
Cdd:pfam13245 90 -----------------------------PLDGDLL----------IVDEFSMVDLpLAYRLLKAL-PDGAQLLLVGDPD 129
|
....*..
gi 15600489 245 QSIYAWR 251
Cdd:pfam13245 130 QLPSVGP 136
|
|
| COG3972 |
COG3972 |
Superfamily I DNA and RNA helicases [Replication, recombination and repair]; |
7-385 |
2.26e-13 |
|
Superfamily I DNA and RNA helicases [Replication, recombination and repair];
Pssm-ID: 443172 [Multi-domain] Cd Length: 565 Bit Score: 73.33 E-value: 2.26e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 7 RQQE--AVNYVGGPLLVLAGAGSGKTSVITRKIAYLVQqcgIRAQYIVAVTFTNKA-AREMKERVG-TLLRGGEGKG--- 79
Cdd:COG3972 162 LQQEriARSIPDGPQRIRGVAGSGKTVLLAAKAAYLAL---KHPGWRILVTCFNRSlADHLRDLIPrFLRRFSNGEPedn 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 80 LTVSTFHNLGlniiRKEHERLGYKPGfsifdesdikalltdimqKEYSGDDGVDEiknyigawkndliLPEEALEKARNP 159
Cdd:COG3972 239 VKLIVFHAWG----GKLLKQYGIPPL------------------TFSQPNEAFDE-------------ACKALLEAIQGE 283
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 160 KEQTAaivylhyqrtlraynavdFDdlilqpvklfqehpdvlqkwqnkvrYMLVDEYQDTNASQY-LLVKLLVKDRAQFT 238
Cdd:COG3972 284 IIPPI------------------YD-------------------------AILIDEAQDFEPEFLrLLYQLLKPPKKRLI 320
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 239 VVGDDDQSIYawrgaRPENLMQLKEDFPSLKVVMLEQNYRSTSRILKCAN----------VLIANNPHVFEKQLWSEMG- 307
Cdd:COG3972 321 WAYDEAQNIY-----GRKIPSAGGIPAGIGRDTILKKNYRNTRPILTFAHafgmgllrppGLLQGDAEDYEVERPGDKVt 395
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 308 ----------HGDPIRVIRCRNEDAEAERIAMEILTLHLRTERPYSEFAILYRGNHQAK--LMELK--LQHHQIPYRLSG 373
Cdd:COG3972 396 lirppepagrKGPLPEFKKYDDRAEELEAIAEEIKKNLRDEGLRPSDIAVIYLGNNEAKelGDRLAaaLERQGIDSYIAG 475
|
410
....*....|..
gi 15600489 374 GTSFFGRQEVKD 385
Cdd:COG3972 476 ARSDPNFFWKDG 487
|
|
| HelD |
COG3973 |
DNA helicase IV [Replication, recombination and repair]; |
207-334 |
4.77e-13 |
|
DNA helicase IV [Replication, recombination and repair];
Pssm-ID: 443173 [Multi-domain] Cd Length: 699 Bit Score: 72.20 E-value: 4.77e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 207 KVRYMLVDEYQDTNASQYLLVKLLVKdRAQFTVVGDDDQSIYAWRGARPENLMqLKE-DFPSLKVVMLEQNYRSTSRILK 285
Cdd:COG3973 469 TYGHVVVDEAQDLSPMQWRVLKRRFP-SASFTIVGDLAQAIHPYRGAESWEEV-LEPlGGDRARLVELTKSYRSTAEIME 546
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 15600489 286 CAN-VLIANNPHV-----FEKqlwsemgHGDPIRVIRCRNEDAEAERIAMEILTL 334
Cdd:COG3973 547 FANrVLRAAGPDLpppesVRR-------HGEPPRVVRVPSEAELAAAVVEAVREL 594
|
|
| DExxQc_SF1-N |
cd17914 |
DEXQ-box helicase domain of superfamily 1 helicase; The superfamily (SF)1 family members ... |
206-277 |
8.17e-12 |
|
DEXQ-box helicase domain of superfamily 1 helicase; The superfamily (SF)1 family members include UvrD/Rep, Pif1-like, and Upf-1-like proteins. Like SF2, they do not form toroidal, predominantly hexameric structures like SF3-6. Their helicase core is surrounded by C and N-terminal domains with specific functions such as nucleases, RNA or DNA binding domains or domains engaged in protein-protein interactions. SF1 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438706 [Multi-domain] Cd Length: 121 Bit Score: 62.50 E-value: 8.17e-12
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15600489 206 NKVRYMLVDEYQDTNASQYLLVKLLVKDRAQFTVVGDDDQSIYAWRGARPENLMQLKE-----DFPSLKVVMLEQNY 277
Cdd:cd17914 45 AQLDNILVDEAAQILEPETSRLIDLALDQGRVILVGDHDQLGPVWRGAVLAKICNEQSlftrlVRLGVSLIRLQVQY 121
|
|
| SF1_C |
cd18786 |
C-terminal helicase domain of superfamily 1 DEAD/H-box helicases; Superfamily (SF)1 family ... |
535-611 |
8.47e-11 |
|
C-terminal helicase domain of superfamily 1 DEAD/H-box helicases; Superfamily (SF)1 family members include UvrD/Rep, Pif1-like, and Upf-1-like proteins. Similar to SF2 helicases, they do not form toroidal, predominantly hexameric structures like SF3-6. SF1 helicases are a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Their helicase core is surrounded by C- and N-terminal domains with specific functions such as nucleases, RNA or DNA binding domains, or domains engaged in protein-protein interactions. The core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350173 [Multi-domain] Cd Length: 89 Bit Score: 58.60 E-value: 8.47e-11
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15600489 535 VLRDMLERQQEEEEGAEGVQMMTLHASKGLEFPYVFIMGMEEEilphrssieadtvEEERRLAYVGITRARQNLAMT 611
Cdd:cd18786 25 YLNQYLQGLSLDEFDLQLVGAITIDSSQGLTFDVVTLYLPTAN-------------SLTPRRLYVALTRARKRLVIY 88
|
|
| DExxQc_SF1-N |
cd17914 |
DEXQ-box helicase domain of superfamily 1 helicase; The superfamily (SF)1 family members ... |
18-66 |
2.24e-09 |
|
DEXQ-box helicase domain of superfamily 1 helicase; The superfamily (SF)1 family members include UvrD/Rep, Pif1-like, and Upf-1-like proteins. Like SF2, they do not form toroidal, predominantly hexameric structures like SF3-6. Their helicase core is surrounded by C and N-terminal domains with specific functions such as nucleases, RNA or DNA binding domains or domains engaged in protein-protein interactions. SF1 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438706 [Multi-domain] Cd Length: 121 Bit Score: 55.57 E-value: 2.24e-09
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 15600489 18 PLLVLAGAGSGKTSVITRKIAYLVQQCGIRAQYIVAVTFTNKAAREMKE 66
Cdd:cd17914 1 LSLIQGPPGTGKTRVLVKIVAALMQNKNGEPGRILLVTPTNKAAAQLDN 49
|
|
| UvrD_C_2 |
pfam13538 |
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety ... |
556-606 |
8.96e-07 |
|
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety of helicase enzymes. This domain has a AAA-like structural fold.
Pssm-ID: 463913 [Multi-domain] Cd Length: 52 Bit Score: 46.03 E-value: 8.96e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 15600489 556 MTLHASKGLEFPYVFIMGMEEeilphrssIEADTVEEERRLAYVGITRARQ 606
Cdd:pfam13538 5 LTVHKAQGSEFPAVFLVDPDL--------TAHYHSMLRRRLLYTAVTRARK 47
|
|
| RecD |
COG0507 |
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) ... |
3-69 |
1.53e-06 |
|
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];
Pssm-ID: 440273 [Multi-domain] Cd Length: 514 Bit Score: 51.13 E-value: 1.53e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600489 3 RLNPRQQEAVNYV--GGPLLVLAG-AGSGKTSVItRKIAYLVQQCGIRaqyIVAVTFTNKAAREMKERVG 69
Cdd:COG0507 124 TLSDEQREAVALAltTRRVSVLTGgAGTGKTTTL-RALLAALEALGLR---VALAAPTGKAAKRLSESTG 189
|
|
| DEXSc_RecD-like |
cd17933 |
DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1. ... |
8-69 |
2.64e-05 |
|
DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350691 [Multi-domain] Cd Length: 155 Bit Score: 44.85 E-value: 2.64e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15600489 8 QQEAVNYV-GGPLLVLAG-AGSGKTSVItRKIAYLVQQCGIRaqyIVAVTFTNKAAREMKERVG 69
Cdd:cd17933 2 QKAAVRLVlRNRVSVLTGgAGTGKTTTL-KALLAALEAEGKR---VVLAAPTGKAAKRLSESTG 61
|
|
| SF1_C_RecD |
cd18809 |
C-terminal helicase domain of RecD family helicases; RecD is a member of the RecBCD (EC 3.1.11. ... |
556-606 |
2.86e-05 |
|
C-terminal helicase domain of RecD family helicases; RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD family helicases are DEAD-like helicases belonging to superfamily (SF)1, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF2 helicases, SF1 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350196 [Multi-domain] Cd Length: 80 Bit Score: 42.55 E-value: 2.86e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 15600489 556 MTLHASKGLEFPYVFImgmeeeILPHRSSieadtvEEERRLAYVGITRARQ 606
Cdd:cd18809 36 MTIHKSQGSEFDRVIV------VLPTSHP------MLSRGLLYTALTRARK 74
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| RecD |
COG0507 |
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) ... |
556-630 |
2.19e-04 |
|
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];
Pssm-ID: 440273 [Multi-domain] Cd Length: 514 Bit Score: 44.20 E-value: 2.19e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15600489 556 MTLHASKGLEFPYVFImgmeeeILPHRSSIEADtveeeRRLAYVGITRARQNLamTFAAKRKQYGEIIDCSPSRF 630
Cdd:COG0507 445 ITVHKSQGSTFDRVIL------VLPSEHSPLLS-----RELLYTALTRARELL--TLVGDRDALARAVRRDTARA 506
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|
| DEAD-like_helicase_N |
cd17912 |
N-terminal helicase domain of the DEAD-box helicase superfamily; The DEAD-like helicase ... |
19-64 |
2.24e-04 |
|
N-terminal helicase domain of the DEAD-box helicase superfamily; The DEAD-like helicase superfamily is a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. The N-terminal domain contains the ATP-binding region.
Pssm-ID: 350670 [Multi-domain] Cd Length: 81 Bit Score: 40.20 E-value: 2.24e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 15600489 19 LLVLAGAGSGKTSVITRKIAYLVQQCGiraqYIVAVTFTNKAAREM 64
Cdd:cd17912 2 ILHLGPTGSGKTLVAIQKIASAMSSGK----SVLVVTPTKLLAHEI 43
|
|
| AAA_30 |
pfam13604 |
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ... |
3-69 |
4.93e-04 |
|
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. There is a Walker A and Walker B.
Pssm-ID: 433343 [Multi-domain] Cd Length: 191 Bit Score: 41.78 E-value: 4.93e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15600489 3 RLNPRQQEAVNYV---GGPLLVL-AGAGSGKTSVItRKIAYLVQQCGIRaqyIVAVTFTNKAAREMKERVG 69
Cdd:pfam13604 1 TLNAEQAAAVRALltsGDRVAVLvGPAGTGKTTAL-KALREAWEAAGYR---VIGLAPTGRAAKVLGEELG 67
|
|
| recB |
PRK10876 |
exonuclease V subunit beta; Provisional |
553-604 |
1.05e-03 |
|
exonuclease V subunit beta; Provisional
Pssm-ID: 236784 [Multi-domain] Cd Length: 1181 Bit Score: 42.27 E-value: 1.05e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15600489 553 VQMMTLHASKGLEFPYV---FIMG--MEEEILPH-RSSIEA-----------DTVEEER-----RLAYVGITRA 604
Cdd:PRK10876 736 VQIVTIHKSKGLEYPLVwlpFITNfrVQDQAFYHdRHSFEAvldlnaaeesvALAEEERlaedlRLLYVALTRS 809
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