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Conserved domains on  [gi|1447699370|ref|NP_309145|]
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phage tail assembly protein [Escherichia coli O157:H7 str. Sakai]

Protein Classification

tail assembly protein( domain architecture ID 8240)

tail assembly protein similar to Ravinvirus N15 tail tip assembly protein I that plays a role in tail tip complex assembly

Gene Ontology:  GO:0098003

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Lambda_tail_I super family cl01945
Bacteriophage lambda tail assembly protein I; This family consists of tail assembly proteins ...
 2-181 1.42e-55

Bacteriophage lambda tail assembly protein I; This family consists of tail assembly proteins from lambdoid and T1 phages and related prophages, e.g. the tail assembly protein I (TAPI). Members of this family contain a core ubiquitin fold domain. The exact function of TAPI is not clear but it is not incorporated into the mature tail. Gene neighborhoods reveal that TAPI co-occurs with genes encoding the host-specificity protein TapJ, and TapK, which contains a JAB metallopeptidase fused to an NlpC/P60 peptidase. It is proposed that the TAPI protein is processed by the peptidase domains of TapK.


The actual alignment was detected with superfamily member COG4723:

Pssm-ID: 470403  Cd Length: 197  Bit Score: 174.33  E-value: 1.42e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699370   2 NTAAEAIRALSMQMPGFRRQMNEG-----WYQIRIAGDDTAPEAVyarlhEQLGEGTVIHIVPRLAGAGKGGL-QIVLGA 75
Cdd:COG4723    24 ASPAEAIRALCVTIPGFEQFMRTShkrglTYAVFRGKRNIGEDEL-----ELPVGGADIRIVPVIIGAKRGGLfQTILGA 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699370  76 AAIVGSFFTAGASMALWGSALAAggfsattMLFSLGASMILGGVAQMLAPKAKTPDYRATDNGRQNTYFSSLDNMIAQGN 155
Cdd:COG4723    99 ALIVAAFFFGGGSLAAFGGGAAG-------ALAMLGASMALGGVVQMLSPQPKGLSSRQSPDNKPSYAFGGPVNTTAQGN 171

                         170       180
                  ....*....|....*....|....*.
gi 1447699370 156 PMPVPYGEMLVGSRRISQDISTRDEG 181
Cdd:COG4723   172 PVPLLYGERRIGGAVISAGIYAEDQQ 197
 
Name Accession Description Interval E-value
COG4723 COG4723
Phage-related protein, tail assembly protein I [Mobilome: prophages, transposons];
2-181 1.42e-55

Phage-related protein, tail assembly protein I [Mobilome: prophages, transposons];


Pssm-ID: 443758  Cd Length: 197  Bit Score: 174.33  E-value: 1.42e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699370   2 NTAAEAIRALSMQMPGFRRQMNEG-----WYQIRIAGDDTAPEAVyarlhEQLGEGTVIHIVPRLAGAGKGGL-QIVLGA 75
Cdd:COG4723    24 ASPAEAIRALCVTIPGFEQFMRTShkrglTYAVFRGKRNIGEDEL-----ELPVGGADIRIVPVIIGAKRGGLfQTILGA 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699370  76 AAIVGSFFTAGASMALWGSALAAggfsattMLFSLGASMILGGVAQMLAPKAKTPDYRATDNGRQNTYFSSLDNMIAQGN 155
Cdd:COG4723    99 ALIVAAFFFGGGSLAAFGGGAAG-------ALAMLGASMALGGVVQMLSPQPKGLSSRQSPDNKPSYAFGGPVNTTAQGN 171

                         170       180
                  ....*....|....*....|....*.
gi 1447699370 156 PMPVPYGEMLVGSRRISQDISTRDEG 181
Cdd:COG4723   172 PVPLLYGERRIGGAVISAGIYAEDQQ 197
Lambda_tail_I pfam06805
Bacteriophage lambda tail assembly protein I; This family consists of tail assembly proteins ...
 3-64 2.67e-05

Bacteriophage lambda tail assembly protein I; This family consists of tail assembly proteins from lambdoid and T1 phages and related prophages, e.g. the tail assembly protein I (TAPI). Members of this family contain a core ubiquitin fold domain. The exact function of TAPI is not clear but it is not incorporated into the mature tail. Gene neighborhoods reveal that TAPI co-occurs with genes encoding the host-specificity protein TapJ, and TapK, which contains a JAB metallopeptidase fused to an NlpC/P60 peptidase. It is proposed that the TAPI protein is processed by the peptidase domains of TapK.


Pssm-ID: 284272  Cd Length: 82  Bit Score: 41.02  E-value: 2.67e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1447699370   3 TAAEAIRALSMQMPGFRRqmnegWYQIRIAGDDTAPEAVYARLHEQLGEGTVIHIVPRLAGA 64
Cdd:pfam06805  26 TLGEAIRALGIQEDCFEA-----LSDGPEAGVDGMTVPVGIYAVETIVDGEVVTIVPWPAGG 82
 
Name Accession Description Interval E-value
COG4723 COG4723
Phage-related protein, tail assembly protein I [Mobilome: prophages, transposons];
2-181 1.42e-55

Phage-related protein, tail assembly protein I [Mobilome: prophages, transposons];


Pssm-ID: 443758  Cd Length: 197  Bit Score: 174.33  E-value: 1.42e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699370   2 NTAAEAIRALSMQMPGFRRQMNEG-----WYQIRIAGDDTAPEAVyarlhEQLGEGTVIHIVPRLAGAGKGGL-QIVLGA 75
Cdd:COG4723    24 ASPAEAIRALCVTIPGFEQFMRTShkrglTYAVFRGKRNIGEDEL-----ELPVGGADIRIVPVIIGAKRGGLfQTILGA 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699370  76 AAIVGSFFTAGASMALWGSALAAggfsattMLFSLGASMILGGVAQMLAPKAKTPDYRATDNGRQNTYFSSLDNMIAQGN 155
Cdd:COG4723    99 ALIVAAFFFGGGSLAAFGGGAAG-------ALAMLGASMALGGVVQMLSPQPKGLSSRQSPDNKPSYAFGGPVNTTAQGN 171

                         170       180
                  ....*....|....*....|....*.
gi 1447699370 156 PMPVPYGEMLVGSRRISQDISTRDEG 181
Cdd:COG4723   172 PVPLLYGERRIGGAVISAGIYAEDQQ 197
Lambda_tail_I pfam06805
Bacteriophage lambda tail assembly protein I; This family consists of tail assembly proteins ...
 3-64 2.67e-05

Bacteriophage lambda tail assembly protein I; This family consists of tail assembly proteins from lambdoid and T1 phages and related prophages, e.g. the tail assembly protein I (TAPI). Members of this family contain a core ubiquitin fold domain. The exact function of TAPI is not clear but it is not incorporated into the mature tail. Gene neighborhoods reveal that TAPI co-occurs with genes encoding the host-specificity protein TapJ, and TapK, which contains a JAB metallopeptidase fused to an NlpC/P60 peptidase. It is proposed that the TAPI protein is processed by the peptidase domains of TapK.


Pssm-ID: 284272  Cd Length: 82  Bit Score: 41.02  E-value: 2.67e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1447699370   3 TAAEAIRALSMQMPGFRRqmnegWYQIRIAGDDTAPEAVYARLHEQLGEGTVIHIVPRLAGA 64
Cdd:pfam06805  26 TLGEAIRALGIQEDCFEA-----LSDGPEAGVDGMTVPVGIYAVETIVDGEVVTIVPWPAGG 82
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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