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Conserved domains on  [gi|15830499|ref|NP_309272|]
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regulatory protein MokC for HokC [Escherichia coli O157:H7 str. Sakai]

Protein Classification

type I toxin-antitoxin system Hok family toxin( domain architecture ID 10486807)

type I toxin-antitoxin system Hok family toxin similar to Hok, a small, toxic protein encoded on the parB (hok/sok) locus of plasmid R1, that mediates plasmid stabilization by killing plasmid-free cells

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HOK_GEF pfam01848
Hok/gef family;
26-66 1.49e-12

Hok/gef family;


:

Pssm-ID: 426473  Cd Length: 41  Bit Score: 55.46  E-value: 1.49e-12
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 15830499   26 MLIALIVICLTVIVTALVTRKDLCEVRIRTGQTEVAVFVDY 66
Cdd:pfam01848  1 ALVALIVICITVLLFTLVTRKSLCELRIRQGQTEVAAFLAC 41
 
Name Accession Description Interval E-value
HOK_GEF pfam01848
Hok/gef family;
26-66 1.49e-12

Hok/gef family;


Pssm-ID: 426473  Cd Length: 41  Bit Score: 55.46  E-value: 1.49e-12
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 15830499   26 MLIALIVICLTVIVTALVTRKDLCEVRIRTGQTEVAVFVDY 66
Cdd:pfam01848  1 ALVALIVICITVLLFTLVTRKSLCELRIRQGQTEVAAFLAC 41
PRK09738 PRK09738
small toxic polypeptide; Provisional
 26-70 1.47e-08

small toxic polypeptide; Provisional


Pssm-ID: 182055  Cd Length: 52  Bit Score: 45.55  E-value: 1.47e-08
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*
gi 15830499  26 MLIALIVICLTVIVTALVTRKDLCEVRIRTGQTEVAVFVDYESEK 70
Cdd:PRK09738  8 LVWCVLIVCLTLLIFTYLTRKSLCELRYRDGDREVAAFMAYESGK 52
 
Name Accession Description Interval E-value
HOK_GEF pfam01848
Hok/gef family;
26-66 1.49e-12

Hok/gef family;


Pssm-ID: 426473  Cd Length: 41  Bit Score: 55.46  E-value: 1.49e-12
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 15830499   26 MLIALIVICLTVIVTALVTRKDLCEVRIRTGQTEVAVFVDY 66
Cdd:pfam01848  1 ALVALIVICITVLLFTLVTRKSLCELRIRQGQTEVAAFLAC 41
PRK09738 PRK09738
small toxic polypeptide; Provisional
 26-70 1.47e-08

small toxic polypeptide; Provisional


Pssm-ID: 182055  Cd Length: 52  Bit Score: 45.55  E-value: 1.47e-08
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*
gi 15830499  26 MLIALIVICLTVIVTALVTRKDLCEVRIRTGQTEVAVFVDYESEK 70
Cdd:PRK09738  8 LVWCVLIVCLTLLIFTYLTRKSLCELRYRDGDREVAAFMAYESGK 52
PRK09759 PRK09759
type I toxin-antitoxin system toxin HokA;
23-64 2.30e-06

type I toxin-antitoxin system toxin HokA;


Pssm-ID: 182063  Cd Length: 50  Bit Score: 39.91  E-value: 2.30e-06
                        10        20        30        40
                ....*....|....*....|....*....|....*....|..
gi 15830499  23 QKAMLIALIVICLTVIVTALVTRKDLCEVRIRTGQTEVAVFV 64
Cdd:PRK09759  3 QKYRLLSLIVICFTLLFFTWMIRDSLCELHIKQGSYELAAFL 44
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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