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Conserved domains on  [gi|15830917|ref|NP_309690|]
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outer membrane protease VII [Escherichia coli O157:H7 str. Sakai]

Protein Classification

omptin family outer membrane protease( domain architecture ID 10013698)

omptin family outer membrane protease similar to Escherichia coli protease VII that can cleave T7 RNA polymerase, ferric enterobactin receptor protein (FEP), antimicrobial peptide protamine and other proteins

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
PRK10993 PRK10993
omptin family outer membrane protease;
1-317 0e+00

omptin family outer membrane protease;


:

Pssm-ID: 236813  Cd Length: 314  Bit Score: 501.47  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830917    1 MRAKLLGIVLTTPIAISSFASTETLS--FTPDNINADISLGTLSGKTKERVYlAEEGGRKVSQLDWKFNNAAIIKGAINW 78
Cdd:PRK10993   1 MKKKLLAIALIAPLAISAFASTATASfdVTPDNVSVSISLGTLSGKSKELVY-DEEGGRKLSQLDWKIKNAAIIKGDINW 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830917   79 DLMPQISIGAAGWTTLGSRGGNMVDQDWMDSSNPGtWTDESRHPDTQLNYANEFDLNIKGWLLNEPNYRLGLMAGYQESR 158
Cdd:PRK10993  80 DLLPRLSLGASGWTTLASGGGHMVDYDWLDSSQPG-WTDRSHHPDTDLNYANEFDLNLKGWLLQNPNYRLGVMAGYQETR 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830917  159 YSFTARGGSYIYSsEEGFRDDIGSFPNGERAIGYKQRFKMPYIGLTGSYRYEDFELGGTFKYSGWVEASDNDEHYdpGKR 238
Cdd:PRK10993 159 FSWTAYGGSYIYS-NGGFRDDIGTFPDGERGIGYKQRFKMPYIGLTGSYRYDDFEFGGLLKYSGWVSASDNDEHY--LRN 235

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15830917  239 ITYRSKVKDQNYYSVSVNAGYYVTPNAKVYVEGTWNRVTNKKGNTSLYDHNDNTSDYSKNGAGIENYNFITTAGLKYTF 317
Cdd:PRK10993 236 LTFRDKFKNSPYYSASINAGYYVTPNAKLYVEGAYNRYFEGKGDTQIYDHATGTSSYFKDAAGIENQNYTVTAGLKYRF 314
 
Name Accession Description Interval E-value
PRK10993 PRK10993
omptin family outer membrane protease;
1-317 0e+00

omptin family outer membrane protease;


Pssm-ID: 236813  Cd Length: 314  Bit Score: 501.47  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830917    1 MRAKLLGIVLTTPIAISSFASTETLS--FTPDNINADISLGTLSGKTKERVYlAEEGGRKVSQLDWKFNNAAIIKGAINW 78
Cdd:PRK10993   1 MKKKLLAIALIAPLAISAFASTATASfdVTPDNVSVSISLGTLSGKSKELVY-DEEGGRKLSQLDWKIKNAAIIKGDINW 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830917   79 DLMPQISIGAAGWTTLGSRGGNMVDQDWMDSSNPGtWTDESRHPDTQLNYANEFDLNIKGWLLNEPNYRLGLMAGYQESR 158
Cdd:PRK10993  80 DLLPRLSLGASGWTTLASGGGHMVDYDWLDSSQPG-WTDRSHHPDTDLNYANEFDLNLKGWLLQNPNYRLGVMAGYQETR 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830917  159 YSFTARGGSYIYSsEEGFRDDIGSFPNGERAIGYKQRFKMPYIGLTGSYRYEDFELGGTFKYSGWVEASDNDEHYdpGKR 238
Cdd:PRK10993 159 FSWTAYGGSYIYS-NGGFRDDIGTFPDGERGIGYKQRFKMPYIGLTGSYRYDDFEFGGLLKYSGWVSASDNDEHY--LRN 235

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15830917  239 ITYRSKVKDQNYYSVSVNAGYYVTPNAKVYVEGTWNRVTNKKGNTSLYDHNDNTSDYSKNGAGIENYNFITTAGLKYTF 317
Cdd:PRK10993 236 LTFRDKFKNSPYYSASINAGYYVTPNAKLYVEGAYNRYFEGKGDTQIYDHATGTSSYFKDAAGIENQNYTVTAGLKYRF 314
Omptin pfam01278
Omptin family; The omptin family is a family of serine proteases.
 28-317 2.79e-155

Omptin family; The omptin family is a family of serine proteases.


Pssm-ID: 426174  Cd Length: 282  Bit Score: 435.63  E-value: 2.79e-155
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830917    28 TPDNINADISLGTLSGKTKERVYLAEeGGRKVSQLDWKFNNAAIIKGAINWDLMPQISIGAAGWTTLGSRGGNMVDQDWM 107
Cdd:pfam01278   1 TPDNFSLSTSLGVLSGKAKEYVYDPE-TGRKLSQLDWKIKNAAIIKGEIEWDITPRLTLSASGWTTLASGSGVMDDYDWL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830917   108 DSSNPgTWTDESRHPDTQLNYANEFDLNIKGWLLNEPNYRLGLMAGYQESRYSFTARGGSYIYSseegFRDDIGSFPNGE 187
Cdd:pfam01278  80 DPNQP-TWTDWSHHPDTQLNYANEADLNAKGWLLQQNNYRLGALAGYQETRFSWTARGGSYSYN----NGTDIGSFPDGV 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830917   188 RAIGYKQRFKMPYIGLTGSYRYEDFELGGTFKYSGWVEASDNDEHYDpgKRITYRSKVKDQNYYSVSVNAGYYVTPNAKV 267
Cdd:pfam01278 155 RGIGYKQRFKMPYIGLAGSYRINNFEFNALLKYSPWVRARDNDNHYL--RSLTFKDKSKNSNYYSLSINAGYYVTPNAKL 232

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 15830917   268 YVEGTWNRVTNKKGNTSLYDHNDNTSDYSKNGAGIENYNFITTAGLKYTF 317
Cdd:pfam01278 233 FLEAAWNRYSNGKGDTTILDNRTGTSSVGENSAGIENQNYTLTVGLQYRF 282
OmpT COG4571
Outer membrane protease [Cell wall/membrane/envelope biogenesis];
1-317 3.35e-154

Outer membrane protease [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443628  Cd Length: 315  Bit Score: 434.03  E-value: 3.35e-154
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830917   1 MRAKLL-GIVLTTPIAISSFASTET--LSFTPDNINADISLGTLSGKTKERVYLaEEGGRKVSQLDWKFNNAAIIKGAIN 77
Cdd:COG4571   1 MKKKLLvALFLLAPLALPALANAATvePEFTPDSVSFSLSLGVLSGESKEYVYD-PDGGRKLSQLDWKIDNAPIIKGGLS 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830917  78 WDLMPQISIGAAGWTTLGSRGGNMVDQDWMDSSNPGtWTDESRHPDTQLNYANEFDLNIKGWLLNEPNYRLGLMAGYQES 157
Cdd:COG4571  80 WDPLPWLSLGASGWTTLGSGSGYMDDYDWLNPGQTD-WTDWSSHPKTRLNYANEFDLNAKGWLLKENNYSLGVLAGYQED 158

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830917 158 RYSFTARGGSYIYSsEEGFRDDIGSFPNGERAIGYKQRFKMPYIGLTGSYRYEDFELGGTFKYSGWVEASDNDEHYdpGK 237
Cdd:COG4571 159 RFSWTARGGSYIYS-DNGFRDDVGTFPDGEKGISYKQRFKVPYIGLTGSYRYGNWEFGGLLKYSPWVRARDNDHHY--LR 235

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830917 238 RITYRSKVKDQNYYSVSVNAGYYVTPNAKVYVEGTWNRVTNKKGNTSLYDHNDNTSDYSKNGAGIENYNFITTAGLKYTF 317
Cdd:COG4571 236 DLTFKDKFKNSNYYSLSLNAGYYVTPNLKFFVEASYSRYTEAKGDTTIYDLTTGTSSYGGDAAGIDNYSYTVSLGLKYRF 315
 
Name Accession Description Interval E-value
PRK10993 PRK10993
omptin family outer membrane protease;
1-317 0e+00

omptin family outer membrane protease;


Pssm-ID: 236813  Cd Length: 314  Bit Score: 501.47  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830917    1 MRAKLLGIVLTTPIAISSFASTETLS--FTPDNINADISLGTLSGKTKERVYlAEEGGRKVSQLDWKFNNAAIIKGAINW 78
Cdd:PRK10993   1 MKKKLLAIALIAPLAISAFASTATASfdVTPDNVSVSISLGTLSGKSKELVY-DEEGGRKLSQLDWKIKNAAIIKGDINW 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830917   79 DLMPQISIGAAGWTTLGSRGGNMVDQDWMDSSNPGtWTDESRHPDTQLNYANEFDLNIKGWLLNEPNYRLGLMAGYQESR 158
Cdd:PRK10993  80 DLLPRLSLGASGWTTLASGGGHMVDYDWLDSSQPG-WTDRSHHPDTDLNYANEFDLNLKGWLLQNPNYRLGVMAGYQETR 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830917  159 YSFTARGGSYIYSsEEGFRDDIGSFPNGERAIGYKQRFKMPYIGLTGSYRYEDFELGGTFKYSGWVEASDNDEHYdpGKR 238
Cdd:PRK10993 159 FSWTAYGGSYIYS-NGGFRDDIGTFPDGERGIGYKQRFKMPYIGLTGSYRYDDFEFGGLLKYSGWVSASDNDEHY--LRN 235

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15830917  239 ITYRSKVKDQNYYSVSVNAGYYVTPNAKVYVEGTWNRVTNKKGNTSLYDHNDNTSDYSKNGAGIENYNFITTAGLKYTF 317
Cdd:PRK10993 236 LTFRDKFKNSPYYSASINAGYYVTPNAKLYVEGAYNRYFEGKGDTQIYDHATGTSSYFKDAAGIENQNYTVTAGLKYRF 314
Omptin pfam01278
Omptin family; The omptin family is a family of serine proteases.
 28-317 2.79e-155

Omptin family; The omptin family is a family of serine proteases.


Pssm-ID: 426174  Cd Length: 282  Bit Score: 435.63  E-value: 2.79e-155
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830917    28 TPDNINADISLGTLSGKTKERVYLAEeGGRKVSQLDWKFNNAAIIKGAINWDLMPQISIGAAGWTTLGSRGGNMVDQDWM 107
Cdd:pfam01278   1 TPDNFSLSTSLGVLSGKAKEYVYDPE-TGRKLSQLDWKIKNAAIIKGEIEWDITPRLTLSASGWTTLASGSGVMDDYDWL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830917   108 DSSNPgTWTDESRHPDTQLNYANEFDLNIKGWLLNEPNYRLGLMAGYQESRYSFTARGGSYIYSseegFRDDIGSFPNGE 187
Cdd:pfam01278  80 DPNQP-TWTDWSHHPDTQLNYANEADLNAKGWLLQQNNYRLGALAGYQETRFSWTARGGSYSYN----NGTDIGSFPDGV 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830917   188 RAIGYKQRFKMPYIGLTGSYRYEDFELGGTFKYSGWVEASDNDEHYDpgKRITYRSKVKDQNYYSVSVNAGYYVTPNAKV 267
Cdd:pfam01278 155 RGIGYKQRFKMPYIGLAGSYRINNFEFNALLKYSPWVRARDNDNHYL--RSLTFKDKSKNSNYYSLSINAGYYVTPNAKL 232

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 15830917   268 YVEGTWNRVTNKKGNTSLYDHNDNTSDYSKNGAGIENYNFITTAGLKYTF 317
Cdd:pfam01278 233 FLEAAWNRYSNGKGDTTILDNRTGTSSVGENSAGIENQNYTLTVGLQYRF 282
OmpT COG4571
Outer membrane protease [Cell wall/membrane/envelope biogenesis];
1-317 3.35e-154

Outer membrane protease [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443628  Cd Length: 315  Bit Score: 434.03  E-value: 3.35e-154
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830917   1 MRAKLL-GIVLTTPIAISSFASTET--LSFTPDNINADISLGTLSGKTKERVYLaEEGGRKVSQLDWKFNNAAIIKGAIN 77
Cdd:COG4571   1 MKKKLLvALFLLAPLALPALANAATvePEFTPDSVSFSLSLGVLSGESKEYVYD-PDGGRKLSQLDWKIDNAPIIKGGLS 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830917  78 WDLMPQISIGAAGWTTLGSRGGNMVDQDWMDSSNPGtWTDESRHPDTQLNYANEFDLNIKGWLLNEPNYRLGLMAGYQES 157
Cdd:COG4571  80 WDPLPWLSLGASGWTTLGSGSGYMDDYDWLNPGQTD-WTDWSSHPKTRLNYANEFDLNAKGWLLKENNYSLGVLAGYQED 158

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830917 158 RYSFTARGGSYIYSsEEGFRDDIGSFPNGERAIGYKQRFKMPYIGLTGSYRYEDFELGGTFKYSGWVEASDNDEHYdpGK 237
Cdd:COG4571 159 RFSWTARGGSYIYS-DNGFRDDVGTFPDGEKGISYKQRFKVPYIGLTGSYRYGNWEFGGLLKYSPWVRARDNDHHY--LR 235

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830917 238 RITYRSKVKDQNYYSVSVNAGYYVTPNAKVYVEGTWNRVTNKKGNTSLYDHNDNTSDYSKNGAGIENYNFITTAGLKYTF 317
Cdd:COG4571 236 DLTFKDKFKNSNYYSLSLNAGYYVTPNLKFFVEASYSRYTEAKGDTTIYDLTTGTSSYGGDAAGIDNYSYTVSLGLKYRF 315
PRK12580 PRK12580
omptin family plasminogen activator Pla;
2-317 9.36e-94

omptin family plasminogen activator Pla;


Pssm-ID: 79055  Cd Length: 312  Bit Score: 280.86  E-value: 9.36e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830917    2 RAKLLGIVLTTPIAISSFASTETL-SFTPDNINADISLGTLSGKTKERVYLAEEGgRKVSQLDWKFNNAAIIKGAINWDL 80
Cdd:PRK12580   3 KSSIVATIITILSGSANAASSQLIpNISPDSFTVAASTGMLSGKSHEMLYDAETG-RKISQLDWKIKNVAILKGDISWDP 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830917   81 MPQISIGAAGWTTLGSRGGNMVDQDWMDSsNPGTWTDESRHPDTQLNYANEFDLNIKGWLLNEPNYRLGLMAGYQESRYS 160
Cdd:PRK12580  82 YSFLTLNARGWTSLASGSGNMDDYDWMNE-NQSEWTDHSSHPATNVNHANEYDLNVKGWLLQDENYKAGITAGYQETRFS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830917  161 FTARGGSYIYSSEEGfrddIGSFPNGERAIGYKQRFKMPYIGLTGSYRYEDFELGGTFKYSGWVEASDNDEHYdpGKRIT 240
Cdd:PRK12580 161 WTATGGSYSYNNGAY----TGNFPKGVRVIGYNQRFSMPYIGLAGQYRINDFELNALFKFSDWVRAHDNDEHY--MRDLT 234

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15830917  241 YRSKVKDQNYYSVSVNAGYYVTPNAKVYVEGTWNRVTNKKGNTSLYDHNDNTS-DYSKNGAGIENYNFITTAGLKYTF 317
Cdd:PRK12580 235 FREKTSGSRYYGTVINAGYYVTPNAKVFAEFTYSKYDEGKGGTQTIDKNSGDSvSIGGDAAGISNKNYTVTAGLQYRF 312
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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