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Conserved domains on  [gi|15831221|ref|NP_309994|]
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hypothetical protein ECs_1967 [Escherichia coli O157:H7 str. Sakai]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DUF3950 super family cl16120
Domain of unknown function (DUF3950); This presumed domain is functionally uncharacterized. ...
21-50 3.59e-10

Domain of unknown function (DUF3950); This presumed domain is functionally uncharacterized. This domain family is found in bacteria and viruses, and is approximately 30 amino acids in length. There is a conserved NFS sequence motif.


The actual alignment was detected with superfamily member pfam13132:

Pssm-ID: 472859  Cd Length: 30  Bit Score: 49.64  E-value: 3.59e-10
                         10        20        30
                 ....*....|....*....|....*....|
gi 15831221   21 MIEQINIALDQKGSENFSAWVIESCRRELA 50
Cdd:pfam13132  1 MLEQIEIALEQEKTGNFSAWVKEACREKLC 30
 
Name Accession Description Interval E-value
DUF3950 pfam13132
Domain of unknown function (DUF3950); This presumed domain is functionally uncharacterized. ...
21-50 3.59e-10

Domain of unknown function (DUF3950); This presumed domain is functionally uncharacterized. This domain family is found in bacteria and viruses, and is approximately 30 amino acids in length. There is a conserved NFS sequence motif.


Pssm-ID: 404101  Cd Length: 30  Bit Score: 49.64  E-value: 3.59e-10
                         10        20        30
                 ....*....|....*....|....*....|
gi 15831221   21 MIEQINIALDQKGSENFSAWVIESCRRELA 50
Cdd:pfam13132  1 MLEQIEIALEQEKTGNFSAWVKEACREKLC 30
YlcI_YnfO_N NF041551
YlcI/YnfO family protein; The seed alignment of this HMM (86 proteins after ...
9-50 3.08e-04

YlcI/YnfO family protein; The seed alignment of this HMM (86 proteins after non-redundification to a maximum 80 percent amino acid identity) represents are a large expansion relative to PF13132.9 (3 proteins), named DUF3950. Members are small bacterial proteins, often from prophage regions. This model is short (42 amino acids), which high sequence diversity among seed members, and has relatively high cutoffs for its length. Some family members and additional apparent homologs scoring below the current cutoffs of the model include putative DNA-binding proteins such as HicB family antitoxin components of type II toxin-antitoxin systems.


Pssm-ID: 469436  Cd Length: 42  Bit Score: 34.33  E-value: 3.08e-04
                        10        20        30        40
                ....*....|....*....|....*....|....*....|..
gi 15831221   9 RTTTRNIRFPNQMIEQINiALDQKGsENFSAWVIESCRRELA 50
Cdd:NF041551  1 KSTRPTARVPHELREALE-AVKLEG-ESLSQFIVTAVRREIK 40
 
Name Accession Description Interval E-value
DUF3950 pfam13132
Domain of unknown function (DUF3950); This presumed domain is functionally uncharacterized. ...
21-50 3.59e-10

Domain of unknown function (DUF3950); This presumed domain is functionally uncharacterized. This domain family is found in bacteria and viruses, and is approximately 30 amino acids in length. There is a conserved NFS sequence motif.


Pssm-ID: 404101  Cd Length: 30  Bit Score: 49.64  E-value: 3.59e-10
                         10        20        30
                 ....*....|....*....|....*....|
gi 15831221   21 MIEQINIALDQKGSENFSAWVIESCRRELA 50
Cdd:pfam13132  1 MLEQIEIALEQEKTGNFSAWVKEACREKLC 30
YlcI_YnfO_N NF041551
YlcI/YnfO family protein; The seed alignment of this HMM (86 proteins after ...
9-50 3.08e-04

YlcI/YnfO family protein; The seed alignment of this HMM (86 proteins after non-redundification to a maximum 80 percent amino acid identity) represents are a large expansion relative to PF13132.9 (3 proteins), named DUF3950. Members are small bacterial proteins, often from prophage regions. This model is short (42 amino acids), which high sequence diversity among seed members, and has relatively high cutoffs for its length. Some family members and additional apparent homologs scoring below the current cutoffs of the model include putative DNA-binding proteins such as HicB family antitoxin components of type II toxin-antitoxin systems.


Pssm-ID: 469436  Cd Length: 42  Bit Score: 34.33  E-value: 3.08e-04
                        10        20        30        40
                ....*....|....*....|....*....|....*....|..
gi 15831221   9 RTTTRNIRFPNQMIEQINiALDQKGsENFSAWVIESCRRELA 50
Cdd:NF041551  1 KSTRPTARVPHELREALE-AVKLEG-ESLSQFIVTAVRREIK 40
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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