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Conserved domains on  [gi|15832227|ref|NP_311000|]
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Shiga toxin 1 subunit B [Escherichia coli O157:H7 str. Sakai]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SLT_beta super family cl20230
Shiga-like toxin beta subunit; This family represents the B subunit of shiga-like toxin (SLT ...
 2-70 4.08e-40

Shiga-like toxin beta subunit; This family represents the B subunit of shiga-like toxin (SLT or verotoxin) produced by some strains of E.coli associated with hemorrhagic colitis and hemolytic uremic syndrome. SLT's are composed of one enzymatic A subunit and five cell binding B subunits.


The actual alignment was detected with superfamily member pfam02258:

Pssm-ID: 460513  Cd Length: 69  Bit Score: 126.78  E-value: 4.08e-40
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15832227    2 KKTLLIAASLSFFSASALATPDCVTGKVEYTKYNDDDTFTVKVGDKELFTNRWNLQSLLLSAQITGMTV 70
Cdd:pfam02258  1 TPDCVTGKVEYTKYNDDDTFTVKVGDKELFTNRWNLQSLLLSAQITGMTVTIKTNACHNGGGFSEVIFR 69
 
Name Accession Description Interval E-value
SLT_beta pfam02258
Shiga-like toxin beta subunit; This family represents the B subunit of shiga-like toxin (SLT ...
 2-70 4.08e-40

Shiga-like toxin beta subunit; This family represents the B subunit of shiga-like toxin (SLT or verotoxin) produced by some strains of E.coli associated with hemorrhagic colitis and hemolytic uremic syndrome. SLT's are composed of one enzymatic A subunit and five cell binding B subunits.


Pssm-ID: 460513  Cd Length: 69  Bit Score: 126.78  E-value: 4.08e-40
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15832227    2 KKTLLIAASLSFFSASALATPDCVTGKVEYTKYNDDDTFTVKVGDKELFTNRWNLQSLLLSAQITGMTV 70
Cdd:pfam02258  1 TPDCVTGKVEYTKYNDDDTFTVKVGDKELFTNRWNLQSLLLSAQITGMTVTIKTNACHNGGGFSEVIFR 69
COG5591 COG5591
Uncharacterized conserved protein [Function unknown];
1-26 2.24e-03

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 444330  Cd Length: 88  Bit Score: 33.76  E-value: 2.24e-03
                       10        20
               ....*....|....*....|....*...
gi 15832227  1 MKKTLL--IAASLSFFSASALATPDCVT 26
Cdd:COG5591  1 MKKLLLtaLALAALLAAGAALADDDCTN 28
 
Name Accession Description Interval E-value
SLT_beta pfam02258
Shiga-like toxin beta subunit; This family represents the B subunit of shiga-like toxin (SLT ...
 2-70 4.08e-40

Shiga-like toxin beta subunit; This family represents the B subunit of shiga-like toxin (SLT or verotoxin) produced by some strains of E.coli associated with hemorrhagic colitis and hemolytic uremic syndrome. SLT's are composed of one enzymatic A subunit and five cell binding B subunits.


Pssm-ID: 460513  Cd Length: 69  Bit Score: 126.78  E-value: 4.08e-40
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15832227    2 KKTLLIAASLSFFSASALATPDCVTGKVEYTKYNDDDTFTVKVGDKELFTNRWNLQSLLLSAQITGMTV 70
Cdd:pfam02258  1 TPDCVTGKVEYTKYNDDDTFTVKVGDKELFTNRWNLQSLLLSAQITGMTVTIKTNACHNGGGFSEVIFR 69
COG5591 COG5591
Uncharacterized conserved protein [Function unknown];
1-26 2.24e-03

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 444330  Cd Length: 88  Bit Score: 33.76  E-value: 2.24e-03
                       10        20
               ....*....|....*....|....*...
gi 15832227  1 MKKTLL--IAASLSFFSASALATPDCVT 26
Cdd:COG5591  1 MKKLLLtaLALAALLAAGAALADDDCTN 28
YdeI COG3111
Predicted periplasmic protein YdeI with OB-fold, BOF family [Function unknown];
1-43 3.31e-03

Predicted periplasmic protein YdeI with OB-fold, BOF family [Function unknown];


Pssm-ID: 442345  Cd Length: 125  Bit Score: 34.11  E-value: 3.31e-03
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*...
gi 15832227   1 MKKTLLIAASLSFFSASALATPDCVTG-----KVEYTKYNDDDTFTVK 43
Cdd:COG3111   1 MKKTLALAALLALASAPAFAADGGFKGppsaqDGGFTGPSDAAVTTVA 48
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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