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Conserved domains on  [gi|15832228|ref|NP_311001|]
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Shiga toxin 1 subunit A [Escherichia coli O157:H7 str. Sakai]

Protein Classification

ribosome-inactivating family protein( domain architecture ID 10445387)

ribosome-inactivating family protein functions as an inactivator of protein synthesis, similar to Zea mays\tibosome-inactivating protein and Shigella dysenteriae Shiga toxin subunit A

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RIP pfam00161
Ribosome inactivating protein;
30-232 4.15e-43

Ribosome inactivating protein;


:

Pssm-ID: 459695  Cd Length: 197  Bit Score: 146.72  E-value: 4.15e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832228    30 STAKTYVDSLNVIRSAIGTPlqTISSGGTSLLMIDSGTGDNLFAVDVRGIDPEEgrfNNLRLIVERNNLYVTGFVNRtNN 109
Cdd:pfam00161   1 ATADSYRDFIEDLRKALASG--DHVSHGIPVLPPQVPPRQPARWVHVVLVNTGT---SSLTLALRVDNLYLVGFRNR-NG 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832228   110 VFYRFADFSHVTFPGTTAVTLSGDSSYTTLQRVAGISRTGMQINRHSLTTSYLDLMSHS-GTSLTQSVARAMLRFVTVTA 188
Cdd:pfam00161  75 YWYEFSDGSIYAALITGSTTLPFGGSYSLLENGGGANLENVPLGRQQLEEAVSALARYPpGGAPTADLARALAVLIQMVC 154

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 15832228   189 EALRFRQIQRGFRTTLDDLSGRSyvMTAEDVDLTLNWGRLSSVL 232
Cdd:pfam00161 155 EAARFRYIERTVAAGWDEGLGVS--PTGTMVKLENNWGDLSKAL 196
 
Name Accession Description Interval E-value
RIP pfam00161
Ribosome inactivating protein;
30-232 4.15e-43

Ribosome inactivating protein;


Pssm-ID: 459695  Cd Length: 197  Bit Score: 146.72  E-value: 4.15e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832228    30 STAKTYVDSLNVIRSAIGTPlqTISSGGTSLLMIDSGTGDNLFAVDVRGIDPEEgrfNNLRLIVERNNLYVTGFVNRtNN 109
Cdd:pfam00161   1 ATADSYRDFIEDLRKALASG--DHVSHGIPVLPPQVPPRQPARWVHVVLVNTGT---SSLTLALRVDNLYLVGFRNR-NG 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832228   110 VFYRFADFSHVTFPGTTAVTLSGDSSYTTLQRVAGISRTGMQINRHSLTTSYLDLMSHS-GTSLTQSVARAMLRFVTVTA 188
Cdd:pfam00161  75 YWYEFSDGSIYAALITGSTTLPFGGSYSLLENGGGANLENVPLGRQQLEEAVSALARYPpGGAPTADLARALAVLIQMVC 154

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 15832228   189 EALRFRQIQRGFRTTLDDLSGRSyvMTAEDVDLTLNWGRLSSVL 232
Cdd:pfam00161 155 EAARFRYIERTVAAGWDEGLGVS--PTGTMVKLENNWGDLSKAL 196
 
Name Accession Description Interval E-value
RIP pfam00161
Ribosome inactivating protein;
30-232 4.15e-43

Ribosome inactivating protein;


Pssm-ID: 459695  Cd Length: 197  Bit Score: 146.72  E-value: 4.15e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832228    30 STAKTYVDSLNVIRSAIGTPlqTISSGGTSLLMIDSGTGDNLFAVDVRGIDPEEgrfNNLRLIVERNNLYVTGFVNRtNN 109
Cdd:pfam00161   1 ATADSYRDFIEDLRKALASG--DHVSHGIPVLPPQVPPRQPARWVHVVLVNTGT---SSLTLALRVDNLYLVGFRNR-NG 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832228   110 VFYRFADFSHVTFPGTTAVTLSGDSSYTTLQRVAGISRTGMQINRHSLTTSYLDLMSHS-GTSLTQSVARAMLRFVTVTA 188
Cdd:pfam00161  75 YWYEFSDGSIYAALITGSTTLPFGGSYSLLENGGGANLENVPLGRQQLEEAVSALARYPpGGAPTADLARALAVLIQMVC 154

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 15832228   189 EALRFRQIQRGFRTTLDDLSGRSyvMTAEDVDLTLNWGRLSSVL 232
Cdd:pfam00161 155 EAARFRYIERTVAAGWDEGLGVS--PTGTMVKLENNWGDLSKAL 196
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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