|
Name |
Accession |
Description |
Interval |
E-value |
| LacY_symp |
pfam01306 |
LacY proton/sugar symporter; This family is closely related to the sugar transporter family. |
4-411 |
0e+00 |
|
LacY proton/sugar symporter; This family is closely related to the sugar transporter family.
Pssm-ID: 396050 Cd Length: 413 Bit Score: 551.68 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 4 NIPFRN-AYYRFASSYSFLFFIsWSLWWSLYAIWLKGHLGLTGTELGTLYSVNQFTSILFMMFYGIVQDKLGLKKPLIWC 82
Cdd:pfam01306 1 MYPLKNtNFWMFGLFFFFYFFI-MSAYFPFFPIWLHDVNHLSKTDTGIVFSCISLFSILFQPLFGLISDKLGLRKHLLWC 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 83 MSFILVLTGPFMIYVYEPLLQSNFSVGLILGALFFGLGYLAGCGLLDSFTEKMARNFHFEYGTARAWGSFGYAIGAFFAG 162
Cdd:pfam01306 80 ITGLLVLFAPFFIYVFGPLLQSNILVGAIVGGVYLGFVFSAGAGAIEAYIEKVSRRSNFEYGKARMFGCVGWALCASIAG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 163 IFFSISPHINFWLVSLFGAVFMMINMCFK-DKDHQCVAADAGGVKKEDF-----IAVFKDRNFWVFVIFIVGTWSFYNIF 236
Cdd:pfam01306 160 ILFSIDPQIVFWLGSGFALILALLLMFAKpDKSSSAIVADALGANKSAFslrlaLELFRMPKFWVFVLYVVGVACVYDVF 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 237 DQQlFPVFYAGLFESHDVGTRLYGYLNSFQVVLEALCMAIIPFFVNRVGPKNALLIGVVIMALRILSCALFVNPWIISLV 316
Cdd:pfam01306 240 DQQ-FANFFTSFFATPQQGTRVFGYVTTMGELLNALIMFCAPLIINRIGAKNALLIAGTIMSVRILGSSFATTALEVVIL 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 317 KLLHAIEVPLCVISVFKYSVANFDKRLSSTIFLIGFQIASSLGIVLLSTPTGILFDHAGYQTVFFAISGIVCLMLLFGIF 396
Cdd:pfam01306 319 KMLHMFEVPFLLVGCFKYITSQFDVRLSATIYLIGFQFSKQLAMILLSTLAGIMYDSIGFQGAYLVLGGIVLSFTLISVF 398
|
410
....*....|....*
gi 15832495 397 FLSKKREQIVMETPV 411
Cdd:pfam01306 399 TLSGSGPQILLPRPV 413
|
|
| 2A0105 |
TIGR00882 |
oligosaccharide:H+ symporter; [Transport and binding proteins, Carbohydrates, organic alcohols, ... |
9-399 |
0e+00 |
|
oligosaccharide:H+ symporter; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 211613 Cd Length: 396 Bit Score: 524.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 9 NAYYRFASSYSFLFFISWSLWWSLYAIWLKGHLGLTGTELGTLYSVNQFTSILFMMFYGIVQDKLGLKKPLIWCMSFILV 88
Cdd:TIGR00882 1 NTNFWMFGLFFFLYFFIMSAYFPFFPIWLHDVNGLSKTDTGIVFSCISLFSILFQPLFGLISDKLGLKKHLLWIISGLLV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 89 LTGPFMIYVYEPLLQSNFSVGLILGALFFGLGYLAGCGLLDSFTEKMARNFHFEYGTARAWGSFGYAIGAFFAGIFFSIS 168
Cdd:TIGR00882 81 LFAPFFIYVFGPLLQSNILVGAIVGGLYLGFVFSAGAGAIEAYIEKVSRNSNFEYGKARMFGCVGWALCASIAGILFSID 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 169 PHINFWLVSLFGAVFMMINMCFKDKD------HQCVAADAGGVKKEDFIAVFKDRNFWVFVIFIVGTWSFYNIFDQQlFP 242
Cdd:TIGR00882 161 PQIVFWLGSGFALILMLLLMFAKPKApssatvANALGANASAFSLKLALELFRQRKFWMFVLYVVGVACVYDVFDQQ-FA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 243 VFYAGLFESHDVGTRLYGYLNSFQVVLEALCMAIIPFFVNRVGPKNALLIGVVIMALRILSCALFVNPWIISLVKLLHAI 322
Cdd:TIGR00882 240 NFFTSFFATPQQGTRVFGYVTTMGELLNALIMFCAPLIINRIGAKNALLIAGTIMSVRIIGSSFATTALEVVILKMLHAF 319
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15832495 323 EVPLCVISVFKYSVANFDKRLSSTIFLIGFQIASSLGIVLLSTPTGILFDHAGYQTVFFAISGIVCLMLLFGIFFLS 399
Cdd:TIGR00882 320 EVPFLLVGCFKYITSQFDVRLSATIYLIGFQFAKQLAMIFLSTLAGNMYDSIGFQGAYLVLGCIVLLFTLISVFTLS 396
|
|
| lacY |
PRK09528 |
galactoside permease; Reviewed |
1-415 |
0e+00 |
|
galactoside permease; Reviewed
Pssm-ID: 236549 Cd Length: 420 Bit Score: 513.29 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 1 MALNIPFRNAYYRFASSYSFLFFISWSLWWSLYAIWLKGHLGLTGTELGTLYSVNQFTSILFMMFYGIVQDKLGLKKPLI 80
Cdd:PRK09528 1 MATMYYLKNPNYWIFSLFFFFFFFIWSSWFSFFPIWLHDINGLSGTDTGIIFSANSLFALLFQPLYGLISDKLGLKKHLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 81 WCMSFILVLTGPFMIYVYEPLLQSNFSVGLILGALFFGLGYLAGCGLLDSFTEKMARNFHFEYGTARAWGSFGYAIGAFF 160
Cdd:PRK09528 81 WIISGLLVLFGPFFIYVFAPLLQYNILLGAIVGGIYLGFGFLAGAGAIEAYIERVSRRSGFEYGRARMWGSLGWALCAFI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 161 AGIFFSISPHINFWLVSLFGAVFMMINMCFKDKDHQC------VAADAGGVKKEDFIAVFKDRNFWVFVIFIVGTWSFYN 234
Cdd:PRK09528 161 AGILFNINPQINFWLGSGSALILLVLLFFAKPDAPSTakvanaLGANASAVSLKDALALLKLPKFWFLVLYVIGVACFYD 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 235 IFDQQlFPVFYAGLFESHDVGTRLYGYLNSFQVVLEALCMAIIPFFVNRVGPKNALLIGVVIMALRILSCALFVNPWIIS 314
Cdd:PRK09528 241 VFDQQ-FPNFFASFFATPEQGTRVFGYLNSFQVFLEALIMFFAPFIINRIGAKNALLLAGTIMAVRIIGSGFATGPLEVS 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 315 LVKLLHAIEVPLCVISVFKYSVANFDKRLSSTIFLIGFQIASSLGIVLLSTPTGILFDHAGYQTVFFAISGIVCLMLLFG 394
Cdd:PRK09528 320 ILKLLHAFEVPFLLVGVFKYITLNFDVRLSATIYLVGFQFAKQLGAVFLSTLAGNLYDSIGFQGTYLILGGIVLLFTLIS 399
|
410 420
....*....|....*....|.
gi 15832495 395 IFFLSKKREQIVMETPVPSAI 415
Cdd:PRK09528 400 VFTLSGDRELSLLRRQVPEAA 420
|
|
| MFS_LacY |
cd06172 |
LacY proton/sugar symporter family of the Major Facilitator Superfamily of transporters; LacY ... |
12-398 |
4.89e-175 |
|
LacY proton/sugar symporter family of the Major Facilitator Superfamily of transporters; LacY proton/sugar family (also called LacY/RafB family) symporters are integral membrane proteins responsible for the transport of specific beta-glucosides into the cell accompanied by the import of a proton. Members include lactose permease (LacY), raffinose permease (RafB), and sucrose permease, which facilitate the transport of beta-galactosides, raffinose, and sucrose, respectively. The prototypical member, LacY, contains 12 transmembrane helices connected by hydrophilic loops with both N and C termini on the cytoplasmic face. The LacY/RafB permease family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.
Pssm-ID: 340862 [Multi-domain] Cd Length: 389 Bit Score: 494.06 E-value: 4.89e-175
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 12 YRFASSYSFLFFISWSLWWSLYAIWLKGHLGLTGTELGTLYSVNQFTSILFMMFYGIVQDKLGLKKPLIWCMSFILVLTG 91
Cdd:cd06172 1 YWKFSLFFFLFFFIWSASFSFFPIWLTQINHLSGSETGIVFSANSLFALLFQPVYGLISDKLGLKKHLLWFISGLLVLFG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 92 PFMIYVYEPLLQSNFSVGLILGALFFGLGYLAGCGLLDSFTEKMARNFHFEYGTARAWGSFGYAIGAFFAGIFFSISPHI 171
Cdd:cd06172 81 PFFIFVYGPLLQSNILLGAIVGGIYLGFAFLAGCGAIESYIERVSRRFNFEYGRARMWGSLGWALAAFFAGILFNINPNI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 172 NFWLVSLFGAVFMMINMCFKDKDHQCVAA---DAGGVKKEDFIAVFKDRNFWVFVIFIVGTWSFYNIFDQQlFPVFYAGL 248
Cdd:cd06172 161 NFWLGSGFALILLLLLLFAKPEDSDTAAAagaNASSVSLKDVLELFRMPKFWFFILFVIGVSCFYDVFDQQ-FPPYFTSL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 249 FESHDVGTRLYGYLNSFQVVLEALCMAIIPFFVNRVGPKNALLIGVVIMALRILSCALFVNPWIISLVKLLHAIEVPLCV 328
Cdd:cd06172 240 FATPEQGNRVFGYLNSAQVFLEAGMMFLAPLIVNRIGAKNGLLLAGTIMAVRIIGSGLATSPLEISILKLLHAFEVPLLL 319
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 329 ISVFKYSVANFDKRLSSTIFLIGFQIASSLGIVLLSTPTGILFDHAGYQTVFFAISGIVCLMLLFGIFFL 398
Cdd:cd06172 320 VSIFKYITSHFDTRLSATLYLVGFQFAKQLGAVVLSPLAGNLYDSIGFQQTYLVLGGIVLVFTLISVFTL 389
|
|
| MFS_MFSD6 |
cd17335 |
Major facilitator superfamily domain-containing protein 6; Human Major facilitator superfamily ... |
13-395 |
2.39e-24 |
|
Major facilitator superfamily domain-containing protein 6; Human Major facilitator superfamily domain-containing protein 6 (MFSD6) is also called macrophage MHC class I receptor 2 homolog (MMR2). It has been postulated as a possible receptor for human leukocyte antigen (HLA)-B62. MFSD6 is conserved through evolution and appeared before bilateral animals. It belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.
Pssm-ID: 340893 [Multi-domain] Cd Length: 375 Bit Score: 103.43 E-value: 2.39e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 13 RFASSYSFLFFISWSLWwSLYAIWLKgHLGLTGTELGTLYSVNQFTSILFMMFYGIVQDKLGLKKPLIWcMSFILVLTGP 92
Cdd:cd17335 1 RLKLFYFFFFAALGSLL-PFLSVYLK-QLGLSPTQIGILIGIRPFVRFLSAPLWGALADRFGKRKALLL-LSLLAAVLFF 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 93 FMIYVYEPLLQSnFSVGLILGALFFGlgylAGCGLLDSFTEKMARNFHFEYGTARAWGSFGYAIGAFFAGIFFS-----I 167
Cdd:cd17335 78 LSLFFVAQIFWL-LLLLVILGAFFSA----PVVPLVDSITLQYLGEERERYGKQRLWGSIGFGIAALLVGILIDrsstyK 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 168 SPHINFWL--VSLFGAVFMMINMCFKDKDHQcvaadaGGVKKEDFIAVFKDRNFWVFVIFIV---GTWSFYNifdqqlfp 242
Cdd:cd17335 153 NYTIAFYVfaVLMLLALLLALKFPFRPKHPE------PNENTGGLLALLRNPRVLAFLLVAFlmgFGHGLIY-------- 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 243 VFYAGLFESHDVGTRLYGYLNSFQVVLEALCMAIIPFFVNRVGPKNALLIGVVIMALRILSCALFVNPWIISLVKLLHAI 322
Cdd:cd17335 219 SFLFWHLQDLGGSKTLIGLLWTVGVVSEIPFFFFSSRLIQRFGHVGLLYLGLLAYVVRWLLYSFLENPWLVLPIELLHGL 298
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15832495 323 EVPLCVISVFKYSVANFDKRLSSTIFLIGFQIASSLGIVLLSTPTGILFDHAGYQTVF--FAISGIVCLMLLFGI 395
Cdd:cd17335 299 TFALVWAAAVSYASAAAPPGLRATAQGLLQGLYFGLGGGLGSLIGGYLYEAFGARTTFrfFAIAALAGLLAFFLI 373
|
|
| NarK |
COG2223 |
Nitrate/nitrite transporter NarK [Inorganic ion transport and metabolism]; |
19-404 |
9.34e-24 |
|
Nitrate/nitrite transporter NarK [Inorganic ion transport and metabolism];
Pssm-ID: 441825 [Multi-domain] Cd Length: 392 Bit Score: 101.88 E-value: 9.34e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 19 SFLFFISWSLW--WSLYAIWLKGHLGLTGTELGTLYSVNQFTSILFMMFYGIVQDKLGLKKPLIWCMsfILVLTGPFMIY 96
Cdd:COG2223 11 TLAFFLAFGVWylWSVLAPPLAEEFGLSAAQLGLLFAIPVLVGALLRIPLGFLVDRFGPRRVLLIGL--LLLGIGLLLLA 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 97 VYEPLLQsnfsvgLILGALFFGLG----YLAGCGLLDSFTEKmaRNFHFEYGTARAWGSFGYAIGAFFAGIFF-SISPHI 171
Cdd:COG2223 89 LAVSYWL------LLLLGLLLGIGgggsFAVGIALVSKWFPP--DRRGLALGLAAGGGNLGAAVAAFLAPLLIaAFGWRN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 172 NFWLVSLFGAVFMMINMCFKDKDHQCVAADAGGVKKeDFIAVFKDRNFWVFVIFIVGTWSFYNIFDQQlFPVFYAGLFes 251
Cdd:COG2223 161 AFLILGILLLVVAVLAWLFLRDPPAGAAAAAKASLR-DQLEALRDPRFWLLSLLYFGTFGSFIGFSSW-LPPYLVDQF-- 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 252 hDVGTRLYGYLNSFQVVLEALCMAIIPFFVNRVGPKNALLIGVVIMALRILSCALFV-NPWIISLVKLLHAIEVPLCVIS 330
Cdd:COG2223 237 -GLSAATAGLLAALFALLGALGRPLGGWLSDRIGGRRVLLIVFALMALGLLLLALALgSLWLFLVLFLLLGLALGGGNGA 315
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15832495 331 VFKYSVANFDKRLSSTIFLIGFqIASSLGIVLLSTPTGILFDHAG-YQTVFFAISGIVCLMLLFGIFFLSKKREQ 404
Cdd:COG2223 316 VFALVPDIFPTKNAGAVYGLVG-AAGGLGGFLGPLLFGALLDATGsYTAAFLVFAVLALVALVLTLLLYRRPRRA 389
|
|
| MFS_1_like |
pfam12832 |
MFS_1 like family; This family contains proteins related to the MFS superfamily. |
40-382 |
1.38e-11 |
|
MFS_1 like family; This family contains proteins related to the MFS superfamily.
Pssm-ID: 432817 [Multi-domain] Cd Length: 362 Bit Score: 65.34 E-value: 1.38e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 40 HLGLTGTELGTLYSVNQFTSILFMMFYGIVQDKLGLKKPLI------WCMSFILVLTGPFmiyvyepllqSNFSVGLILG 113
Cdd:pfam12832 28 SIGLNPSEIGLITAILPLTRILAPPIWGWLADRTGKRKAVVrlasilAAVLFLSVLFIPI----------SLTFWWLALL 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 114 ALFFGLGYLAGCGLLDSFTEKMARNFHFEYGTARAWGSFGYAIGAFFAGIFFSISPH-INFWLVSLFGAVFMMINMCFKD 192
Cdd:pfam12832 98 VVLFSFFWNAILPQFEVATLQHLGEKRKDYGRQRLWGSVGFALSVFGLGALFDHYSVgLLPSVLFYLFAALMLLSLLLPL 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 193 KDHQCVAADAGGVKKeDFIAVFKDRNFWVFVIFIVGTWSFYNIFDQqlfpvFYAGLFESHDVGTRLYGYLNSFQVVLEAL 272
Cdd:pfam12832 178 APPEMEYESKGGSKA-VFWNLLKQPEVIIFFLAAFLLGFSHGPFYT-----FLFLYLENLGASNTLLGALWALGVVAEIP 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 273 CMAIIPFFVNRVGPKNALLIGVVIMALRILSCALFV-NPWIISLVKLLHAIEVPLCVISVFKYSVANFDKRLSSTIFLIG 351
Cdd:pfam12832 252 LFFYAHRLLRRFGHRNLLIIALLLTALRWLLYAFFVeNPWLVLPIQFLHAISFGLTHAAAIEYVRRIFPGSLQGTGQALY 331
|
330 340 350
....*....|....*....|....*....|.
gi 15832495 352 FQIASSLGIVLLSTPTGILFDHAGYQTVFFA 382
Cdd:pfam12832 332 SGLYFGLGGALGSLIGGQLWDLFGARFTFRA 362
|
|
| MFS_MdtG_SLC18_like |
cd17325 |
bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator ... |
19-399 |
1.48e-11 |
|
bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily of transporters; This family is composed of eukaryotic solute carrier 18 (SLC18) family transporters and related bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as multidrug resistance protein MdtG, from Bacillus subtilis such as multidrug resistance proteins 1 (Bmr1) and 2 (Bmr2), and from Staphylococcus aureus such as quinolone resistance protein NorA. The family also includes Escherichia coli arabinose efflux transporters YfcJ and YhhS. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The SLC18 transporter family includes vesicular monoamine transporters (VAT1 and VAT2), vesicular acetylcholine transporter (VAChT), and SLC18B1, which is proposed to be a vesicular polyamine transporter (VPAT). The MdtG/SLC18 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.
Pssm-ID: 340883 [Multi-domain] Cd Length: 375 Bit Score: 65.29 E-value: 1.48e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 19 SFLFFISWSLWWSLYAIWLKgHLGLTGTELGTLYSVNQFTSILFMMFYGIVQDKLGLKKPLIWcMSFILVLTGPFMIYVY 98
Cdd:cd17325 5 LFLDMLGYGIIIPILPLYAE-SLGASVAQIGLIVAAYALAQLLFSPPAGRLSDRFGRKRLLLL-GLLLLAVSTLLFAFAT 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 99 EPLLqsnFSVGLILGALFFGLGYLAGCGLL-DSFTEKMARNFhfeYGTARAWGSFGYAIGAFFAGIFFS-ISPHINFWLV 176
Cdd:cd17325 83 SYWQ---LLLARFLQGLASAAVWPAAMALIaDIAPPEERGRA---MGIFSSAIGLGFLIGPLLGGLLADaLGYRAPFLVC 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 177 SLFGAVFMMINMCFKDKDH--QCVAADAGGVKKEDFIAVFKDRNFWVFVIFIVGTWSFYNIFdQQLFPVFYAGLFeshDV 254
Cdd:cd17325 157 AALALLALVLALLLLPEPRppPNKRAVSAARLRSGLRLLLRDRRLLALFLAIFVLAFAFGAL-EPFLPLYAAELG---GL 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 255 GTRLYGYLNSFQVVLEALCMAIIPFFVNRVGPKNALLIGVVIMALRILSCALFVNPWIISLVKLLHAIEVPLCVISVFKY 334
Cdd:cd17325 233 SPAQIGLLFGAQGLASALSQPPAGKLSDRIGRKPLILIGLLLSAVALLLLPLATSFWLLLLLLALLGLGLGLVFPATLAL 312
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15832495 335 SVANFDKRLSSTIFLIgFQIASSLGIVLLSTPTGILFDHAGYQTVfFAISGIVCLMLLFGIFFLS 399
Cdd:cd17325 313 LADIVPPEGRGTAMGL-FNTAFSLGMVLGPLLGGFLYDAFGFATP-FLAAAALLLLAAVLFLLLR 375
|
|
| FucP |
COG0738 |
Fucose permease [Carbohydrate transport and metabolism]; |
12-404 |
7.87e-11 |
|
Fucose permease [Carbohydrate transport and metabolism];
Pssm-ID: 440501 [Multi-domain] Cd Length: 391 Bit Score: 63.33 E-value: 7.87e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 12 YRFASSYSFLFFISWSLWWSLYAI---WLKGHLGLTGTELGTLYSVNQFTSILFMMFYGIVQDKLGLKKPLIWcmSFILV 88
Cdd:COG0738 6 YRRALIAIYLLFFLWGFATALWGPlipALKDAFGLSDAQAGLLLFAFFLGYLLASLPAGRLIDRFGYKRGLLL--GLLLM 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 89 LTGPFMIYVYEpllqsnfSVGLILGALFFgLGylAGCGLLDSFTEKMARNFHFEYGTAR-----AWGSFGYAIGAFFAGI 163
Cdd:COG0738 84 ALGLLLFALAP-------SYPLLLLALFL-LG--LGLGLLDVAANPYVAALGPETAASRlnllhAFFSLGALLGPLLGGL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 164 FF----SISPHINFWLVSLFGAVFMMINMCFKDKDHQCVAADAGGVKKEdFIAVFKDRNFWVFVIFIVgtwsFYNIFDQQ 239
Cdd:COG0738 154 LIllglSLSWHLPYLILAVLLLLLALLFLRSKLPEIEEEEEEAAGSAAS-LKSLLKNPRLLLGGLAIF----LYVGAEGA 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 240 LFPVFYAGLFESHDVGTRLYGYLNSFQVVLEALCMAIIPFFVNRVGPKNALLIGVVIMALRILSCALFVNPWI----ISL 315
Cdd:COG0738 229 IGDWLPLYLKDVLGLSEATAALGLSLFWGGMTIGRFLGGFLLKRFGPVRLLRLSALLAAVGLLLALLAPGPWLaligLAL 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 316 VKLLHAIEVPLcvisVFKYSVANFDKRLSSTIFLIGfqIASSLGIVLLSTPTGILFDHAGYQTVFFAISGIVCLMLLFGI 395
Cdd:COG0738 309 VGLGLSLMFPT----IFSLALDGLGKRTAAAVSAVL--IMGIVGGAIGPPLIGFLADAFGLRAAFLVPLVCYLLILLLAL 382
|
....*....
gi 15832495 396 FFLSKKREQ 404
Cdd:COG0738 383 ALKRKRRKK 391
|
|
| MFS |
cd06174 |
Major Facilitator Superfamily; The Major Facilitator Superfamily (MFS) is a large and diverse ... |
15-393 |
1.18e-10 |
|
Major Facilitator Superfamily; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions, sugar phosphates, drugs, neurotransmitters, nucleosides, amino acids, and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate, while symporters and antiporters transport two substrates in the same or in opposite directions, respectively, across membranes. MFS proteins are typically 400 to 600 amino acids in length, and the majority contain 12 transmembrane alpha helices (TMs) connected by hydrophilic loops. The N- and C-terminal halves of these proteins display weak similarity and may be the result of a gene duplication/fusion event. Based on kinetic studies and the structures of a few bacterial superfamily members, GlpT (glycerol-3-phosphate transporter), LacY (lactose permease), and EmrD (multidrug transporter), MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement. Bacterial members function primarily for nutrient uptake, and as drug-efflux pumps to confer antibiotic resistance. Some MFS proteins have medical significance in humans such as the glucose transporter Glut4, which is impaired in type II diabetes, and glucose-6-phosphate transporter (G6PT), which causes glycogen storage disease when mutated.
Pssm-ID: 349949 [Multi-domain] Cd Length: 378 Bit Score: 62.83 E-value: 1.18e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 15 ASSYSFLFFISWSLWWSLYAIWLKgHLGLTGTELGTLYSVNQFTSILFMMFYGIVQDKLGLKKPLIWCMSFILVLTGPFM 94
Cdd:cd06174 1 LLLGFFLTGLARGLISPLLPALLQ-SFGLSASQLGLLFALFSLGYALLQPLAGLLADRFGRRPVLLLGLLLFALGALLFA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 95 IYVYEPLLqsnfSVGLILGALFFGLGYLAGCGLLDSFTEKMARNFHFeyGTARAWGSFGYAIGAFFAGIFFSISPHINFW 174
Cdd:cd06174 80 FAPSFWLL----LLGRFLLGLGSGLIDPAVLALIADLFPERERGRAL--GLLQAFGSVGGILGPLLGGILASSLGFGWRA 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 175 LVSLFGAV----FMMINMCFKDKDHQCVAADAGGVKK---EDFIAVFKDRNFWVFVIFIVGTWSFYNIFdqqlFPVFYAG 247
Cdd:cd06174 154 VFLIAAALallaAILLLLVVPDPPESARAKNEEASSKsvlKLLKRVLKNPGLWLLLLAIFLVNLAYYSF----STLLPLF 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 248 LFESHDVGTRLYGYLNSFQVVLEALCMAIIPFFVNRV-GPKNALLIGVVIMALRILSCALFVNPWIISLVKLLHAIEVPL 326
Cdd:cd06174 230 LLDLGGLSVAVAGLLLSLFGLAGALGSLLLGLLSDRLiGRKPLLLIGLLLMALGLALLLLAPSLLLLLLLLLLLGFGLGG 309
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15832495 327 CVISVFKYSVANFDKRLSSTIFLIGFQIASSLGIVLLSTPTGILFDHAGYQTVFFAISGIVCLMLLF 393
Cdd:cd06174 310 LLPLSFALIAELFPPEIRGTAFGLLNTFGFLGGAIGPLLAGFLLAATFGLTGAFLVLAVLLLLAAIL 376
|
|
| MFS_MdtH_MDR_like |
cd17329 |
Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the ... |
19-396 |
1.43e-10 |
|
Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily; This family is composed of Escherichia coli MdtH and similar multidrug resistance (MDR) transporters from bacteria and archaea, many of which remain uncharacterized. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtH confers resistance to norfloxacin and enoxacin. MdtH-like MDR transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.
Pssm-ID: 340887 [Multi-domain] Cd Length: 376 Bit Score: 62.24 E-value: 1.43e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 19 SFLFFISWSLWWSLYAIWLKGHLGLTGTELGTLYSVNQFTSILFMMFYGIVQDKLGLKKPLIWCMsFILVLTGPFMIYVY 98
Cdd:cd17329 8 SFLNRLGFFMVWPFMAIYLHQQLGLSASIVGLVLALSAVAGIVASLIGGRLADRFGRKPVMLAGL-LLRALGFALLGFAH 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 99 EPLLqsnFSVGLILGALFFGLGYLAGCGLLDSFTEkmARNFHFEYGTARAWGSFGYAIGAFFAGIFFSISPHINFWLVSL 178
Cdd:cd17329 87 SPWL---FAIALVLTGFGGGLFEPASEAMIADVTT--PENRTRAFSLLYWAINLGVAIGPLLGGLLLLYSFRLLFLAAAV 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 179 FGAVFMMINMCFKDKDHQCVAADAGGVKKEDFIAVFKDRNFWVFVIFIVGTWSFYNifdqQLFPVFYAGLFESHDVGTRL 258
Cdd:cd17329 162 LFLLAALVLLFLLPETRPKRRAAEKTEILRGYKIVLRDRAFLLFLLASFLISLIYF----QLESTLPVYVVEILGLGESL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 259 YGYLNSFQVVLEALCMAIIPFFVNRVGPKNALLIGVVIMALRILSCALFVN--PWIISLVKLLHAIEVPLCVISVFKYSV 336
Cdd:cd17329 238 LGLLLALNALLIVLLQFPVARLVERFRLRKILMIGILLFAIGFAVLAFANTlaVLILAMIVLTLGEMLVFPAVQTLVAAL 317
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15832495 337 ANFDKRLSSTIFligFQIASSLGIVLLSTPTGILFDHAGYQTVF--FAISGIVCLMLLFGIF 396
Cdd:cd17329 318 APPDKRGSYMGF---YALAWGLGRAIGPLVGGLLLDLLGPGLPWliLAALGLIAAALLLGLQ 376
|
|
| MelB |
COG2211 |
Na+/melibiose symporter or related transporter [Carbohydrate transport and metabolism]; |
19-408 |
2.68e-09 |
|
Na+/melibiose symporter or related transporter [Carbohydrate transport and metabolism];
Pssm-ID: 441813 [Multi-domain] Cd Length: 447 Bit Score: 58.76 E-value: 2.68e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 19 SFLFFISWSLWWSLYAIWLKGHLGLTGTELGTLYSVNQFTSILFMMFYGIVQD----KLGLKKPLIWCMSFILVLTGPFM 94
Cdd:COG2211 19 DLGLNLAFGLLSAYLLYFYTDVLGLSAALVGLILLVARLWDAITDPLIGALSDrtrtRWGRRRPWILIGAIPLALSFVLL 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 95 IYVYEPLLQSNFsVGLILGALFFGLGYLAGCGLLDSFTEKMARNFHfEYGTARAWGSFGYAIGAFFAGIF-------FSI 167
Cdd:COG2211 99 FTAPDLSPTGKL-IYALVTYLLLGLAYTLVNIPYSALGAELTPDYE-ERTRLSSWRFAFAGLGGLLASVLppplvaaFGG 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 168 SPHINFWLVSLFGAVFM---MINMCFKDKDHQCVAADAGGVKkEDFIAVFKDRNFWVFVIFIVGTWSFYNIFdQQLFPVF 244
Cdd:COG2211 177 DAALGYRLTALIFAVLGllaFLLTFFGTKERPVPEEEKVSLK-ESLKALLKNRPFLLLLLAYLLFFLALALV-AALLLYY 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 245 YAGLFeshDVGTRLYGYLNSFQVVLEALCMAIIPFFVNRVGPKNALLIGVVIMALRILSCALFV--NPWIISLVKLLHAI 322
Cdd:COG2211 255 FKYVL---GLSAALVGLLLALYFLAALLGAPLWPRLAKRFGKKKAFIIGLLLAALGLLLLFFLGpgNLWLLLVLAALAGI 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 323 E------VPLCVIS-VFKYSVANFDKRLSSTIFLIgFQIASSLGIVLLSTPTGILFDHAGYQT--------------VFF 381
Cdd:COG2211 332 GlgailvLPWAMLAdVVDYDEWKTGRRREGLYFGI-FTFAIKLGQALAGALAGLLLALFGYVAgaaqspsaltgirlLFF 410
|
410 420
....*....|....*....|....*....
gi 15832495 382 AISGIVCL--MLLFGIFFLSKKREQIVME 408
Cdd:COG2211 411 LLPAVLLLlaALLLLFYPLTRERHAEIRA 439
|
|
| MFS_1 |
pfam07690 |
Major Facilitator Superfamily; |
19-322 |
2.05e-08 |
|
Major Facilitator Superfamily;
Pssm-ID: 429598 [Multi-domain] Cd Length: 344 Bit Score: 55.50 E-value: 2.05e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 19 SFLFFISWSLWWSLYAIWLKGHLGLTGTELGTLYSVNQFTSILFMMFYGIVQDKLGLKKPLIWCMsfILVLTGPFMIYVY 98
Cdd:pfam07690 5 AFLAALGRSLLGPALPLLLAEDLGISPTEIGLLLTLFSLGYALAQPLAGRLSDRFGRRRVLLIGL--LLFALGLLLLLFA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 99 EPLLQsnFSVGLILGALFFGLGYLAGCGLLDSFTEKMARNFHFeyGTARAWGSFGYAIGAFFAGIFFSISPHINFWLVSL 178
Cdd:pfam07690 83 SSLWL--LLVLRVLQGLGAGALFPAALALIADWFPPEERGRAL--GLVSAGFGLGAALGPLLGGLLASLFGWRAAFLILA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 179 FGAVFMMINMCFKDKDHQCVAADAGGVKKEDFI----AVFKDRNFWVFVIFIVGTWSFYnifdqqLFPVFYAGLFESHDV 254
Cdd:pfam07690 159 ILSLLAAVLLLLPRPPPESKRPKPAEEARLSLIvawkALLRDPVLWLLLALLLFGFAFF------GLLTYLPLYQEVLGL 232
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15832495 255 GTRLYGYLNSFQVVLEALCMAIIPFFVNRVGPKNALLIGVVIMALRILSCALFVNPWIISLVKLLHAI 322
Cdd:pfam07690 233 SALLAGLLLGLGGLLGAIGRLLLGRLSDRLGRRRRLLLALLLLILAALGLLLLSLTLSSLWLLLALLL 300
|
|
| AraJ |
COG2814 |
Predicted arabinose efflux permease AraJ, MFS family [Carbohydrate transport and metabolism]; |
1-313 |
1.74e-07 |
|
Predicted arabinose efflux permease AraJ, MFS family [Carbohydrate transport and metabolism];
Pssm-ID: 442063 [Multi-domain] Cd Length: 348 Bit Score: 52.67 E-value: 1.74e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 1 MALNIPFRNAYYRFASSYSFLFFISWSLWWSLYAiWLKGHLGLTGTELGTLYSVNQFTSILFMMFYGIVQDKLGLKKPLI 80
Cdd:COG2814 1 MPATPRRRWLALLALALGAFLSGLGIGIVLPALP-LIAADLGASPAQAGLVVTAYLLGAALGAPLAGRLADRFGRRRVLL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 81 WCMS-FILVLTGPFMIYVYEPLLqsnfsVGLILGALFFGLGYLAGCGLLDSFT--EKMARNFhfeyGTARAWGSFGYAIG 157
Cdd:COG2814 80 LGLLlFALGSLLCALAPSLWLLL-----AARFLQGLGAGALFPAALALIADLVppERRGRAL----GLLGAGLGLGPALG 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 158 AFFAGIFFS-ISPHINFWLVSLFGAVFMMINMCFKDKDHqcvaADAGGVKKEDFIAVFKDRNFW-VFVIFIVGTWSFYNI 235
Cdd:COG2814 151 PLLGGLLADlFGWRWVFLVNAVLALLALLLLLRLLPESR----PAARARLRGSLRELLRRPRLLlLLLLAFLLGFGFFAL 226
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15832495 236 FdqQLFPVFyagLFESHDVGTRLYGYLNSFQVVLEALCMAIIPFFVNRVGPKNALLIGVVIMALRILSCALFVNPWII 313
Cdd:COG2814 227 F--TYLPLY---LQEVLGLSASAAGLLLALFGLGGVLGALLAGRLADRFGRRRLLLIGLLLLALGLLLLALAGSLWLL 299
|
|
| UhpC |
COG2271 |
Sugar phosphate permease [Carbohydrate transport and metabolism]; |
217-399 |
1.23e-06 |
|
Sugar phosphate permease [Carbohydrate transport and metabolism];
Pssm-ID: 441872 [Multi-domain] Cd Length: 363 Bit Score: 50.25 E-value: 1.23e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 217 RNFWVFVIFIVGTWsFYNIFDQQLFPVFYAGLFESHDVGTRLYGYLNSFQVVLEALCMAIIPFFVNRVGPKNALLIGVVI 296
Cdd:COG2271 6 RYRWRILALLFLAY-FLNYLDRSNLSVAAPPLQADLGLSAAQLGLLASAFFLGYALGQIPAGLLADRFGRRRVLAIGLLL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 297 MALRILSCALFVNPWIISLVKLLHAIEVPLCVISVFKYSVANFDKRLSSTIFLIgFQIASSLGIVLLSTPTGILFDHAGY 376
Cdd:COG2271 85 WGLATLLFGFATSFWQLLLLRFLLGLGEAGFFPAALKLIAEWFPPKERGRALGI-FNAGGPLGGALAPPLLGWLLAAFGW 163
|
170 180
....*....|....*....|...
gi 15832495 377 QTVFFAISGIVCLMLLFGIFFLS 399
Cdd:COG2271 164 RAAFLILGLPGLLLALLRFWLLA 186
|
|
| MFS_NHS |
cd06177 |
Nucleoside:H(+) symporter family of the Major Facilitator Superfamily of transporters; The ... |
19-397 |
3.63e-06 |
|
Nucleoside:H(+) symporter family of the Major Facilitator Superfamily of transporters; The prototypical members of the Nucleoside:H(+) symporter (NHS) family are Escherichia coli nucleoside permease NupG and xanthosine permease. Nucleoside:H(+) symporters are proton-driven transporters that facilitate the import of nucleosides across the cytoplasmic membrane. NupG is a broad-specificity transporter of purine and pyrimidine nucleosides. Xanthosine permease is involved in the uptake of xanthosine and other nucleosides such as inosine, adenosine, cytidine, uridine and thymidine. The NHS family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.
Pssm-ID: 340866 [Multi-domain] Cd Length: 386 Bit Score: 48.78 E-value: 3.63e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 19 SFLFFISWSLWWSLYAIWLKGHLGLTGTELGTLYSVNQFTSILFMMFYGIVQDKlglKKPLIWCMSFILVLTGPFMIYVY 98
Cdd:cd06177 6 MFLQFFIWGAWLVTLGGYMGSTLGFTGAQIGAVYSTTGIAAIIMPFFLGIIADR---FFAAEKVLAVLHLIGAAALFYAA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 99 EpllQSNFSVgLILGALFFGLGYLAGCGLLDSFTEKMARNFHFEYGTARAWGSFGYAIGAFFAGIFFSISPHINFWLVSl 178
Cdd:cd06177 83 T---VTDFSV-FFWVMLLYSLCYMPTLALTNSIAFSNLEDPVKDFPPIRVWGTIGWIAAGWPVGFLGWEASNLQFYIAA- 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 179 fGAVFMMINMCFKdKDHQCVAADAGGVKK-----EDFIAVFKDRNFWVFVIFivgtwSFYNIFDQQLFPVFYAGLFESHD 253
Cdd:cd06177 158 -GASLLLGLYSLT-LPHTPPKKAGKGVSKrsllgLDAFVLLKNPFFAVFFIF-----SFLLGAPLQFYYTFANPFLNDFG 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 254 VGTRLYGYLNSFQVVLEALCMAIIPFFVNRVGPKNALLIGVVIMALRILSCALFvNP----WIISLVKLLHAIEVPLCVI 329
Cdd:cd06177 231 MIVKNPAGIMSLGQISEILFMLAIPFFLKRLGIKKVMLIGMLAWVLRFGLFAYG-DPspgvWMLVLSIILHGVCYDFFFV 309
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15832495 330 SVFKYSVANFDKRLSST--------IFLIGFQIASSLG--IVLLSTPTGILFDHAGYQTVFFAISGIVclMLLFGIFF 397
Cdd:cd06177 310 TGYIYVDKKAPKDIRASaqglfmlmTNGVGALVGSILSgkVVDKFTTVEGTKDWQTIWLVPAIYALVL--AILFALFF 385
|
|
| MelB |
COG2211 |
Na+/melibiose symporter or related transporter [Carbohydrate transport and metabolism]; |
7-182 |
4.00e-06 |
|
Na+/melibiose symporter or related transporter [Carbohydrate transport and metabolism];
Pssm-ID: 441813 [Multi-domain] Cd Length: 447 Bit Score: 48.74 E-value: 4.00e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 7 FRNAYYRFASSYSFLFFISWSLWWSLYAIWLKGHLGLTGTELGTLYSVNQFTSILFMMFYGIVQDKLGLKKPLIWCMSFI 86
Cdd:COG2211 225 LKNRPFLLLLLAYLLFFLALALVAALLLYYFKYVLGLSAALVGLLLALYFLAALLGAPLWPRLAKRFGKKKAFIIGLLLA 304
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 87 LVLTGPFMIYVYEPLlqsnfsVGLILGALFFGLGYLAGCGLLDSFTEKMARNFHFEYGTARAwgSFGYAIGAFFAGIFFS 166
Cdd:COG2211 305 ALGLLLLFFLGPGNL------WLLLVLAALAGIGLGAILVLPWAMLADVVDYDEWKTGRRRE--GLYFGIFTFAIKLGQA 376
|
170
....*....|....*.
gi 15832495 167 ISPHINFWLVSLFGAV 182
Cdd:COG2211 377 LAGALAGLLLALFGYV 392
|
|
| AraJ |
COG2814 |
Predicted arabinose efflux permease AraJ, MFS family [Carbohydrate transport and metabolism]; |
222-398 |
4.86e-05 |
|
Predicted arabinose efflux permease AraJ, MFS family [Carbohydrate transport and metabolism];
Pssm-ID: 442063 [Multi-domain] Cd Length: 348 Bit Score: 44.96 E-value: 4.86e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 222 FVIFIVGTWSFYNIFDQQLFPVFYAGLFESHDVGTRLYGYLNSFQVVLEALCMAIIPFFVNRVGPKNALLIGVVIMALRI 301
Cdd:COG2814 10 LALLALALGAFLSGLGIGIVLPALPLIAADLGASPAQAGLVVTAYLLGAALGAPLAGRLADRFGRRRVLLLGLLLFALGS 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 302 LSCALFVNPWIISLVKLLHAIEVPLCVISVFKYSVANFDKRLSSTIFLIgFQIASSLGIVLLSTPTGILFDHAGYQTVFF 381
Cdd:COG2814 90 LLCALAPSLWLLLAARFLQGLGAGALFPAALALIADLVPPERRGRALGL-LGAGLGLGPALGPLLGGLLADLFGWRWVFL 168
|
170
....*....|....*..
gi 15832495 382 AISGIVCLMLLFGIFFL 398
Cdd:COG2814 169 VNAVLALLALLLLLRLL 185
|
|
| MFS_MefA_like |
cd06173 |
Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of ... |
48-397 |
5.72e-05 |
|
Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters; This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.
Pssm-ID: 340863 [Multi-domain] Cd Length: 383 Bit Score: 44.91 E-value: 5.72e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 48 LGTLYSVNQFTSILFMMFYGIVQDKLGLKKPLIWC--MSFILVLTGPFMIYVYEPLLQSNFSVGLILGAL--FFGLGYLA 123
Cdd:cd06173 36 VGLVLAAFFLPFLLFSPFAGVLADRFDRRRLLILAdlLRALLAAVLALLALLGSLSLWLLLVLAFLLGIAsaFFGPARQA 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 124 gcglldSFTEKMARNfhfEYGTARAWGSFGYAIGAFF----AGIFFS-ISPHINFWL--VSLFGAVFMMINMCFKDKDHQ 196
Cdd:cd06173 116 ------LLPELVPKE---QLVRANALNSLATQLARIIgpalGGLLVAlLGPGGAFAInaLSFLLSALLLLFIRRPPPAAP 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 197 CVAADAGGVKKEDFIAVFKDRNFWVFVIFIVGTWSFYNIFDQQLFPVFyagLFESHDVGTRLYGYLNSFQVVLEALCMAI 276
Cdd:cd06173 187 GESSSLLLRDLREGLRYLRRSPLLRLLLLALALFALLGGALTVLLPLL---AKEVLGGGAAGYGLLLAAFGVGALLGALL 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 277 IPFFVNRVGPKNALLIGVVIMALRILSCALFVNPWIISLVKLLHAIEVPLCVISVFKYSVANFDKRLSSTIFliGFQIAS 356
Cdd:cd06173 264 LGRLSKRRRRGRLLLIGALLLGLALLVLGLSPSLWLLLAALFLLGLAGGLFNVPLNTLLQLRVPDELRGRVF--SVYNAL 341
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 15832495 357 SLGIVLLSTP-TGILFDHAGYQTVFFAISGIVCLMLLFGIFF 397
Cdd:cd06173 342 NSGAMPLGALlAGLLADALGLSAVFLLAGALLLLAALLLLLL 383
|
|
| MFS_MdtG_SLC18_like |
cd17325 |
bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator ... |
7-186 |
1.34e-04 |
|
bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily of transporters; This family is composed of eukaryotic solute carrier 18 (SLC18) family transporters and related bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as multidrug resistance protein MdtG, from Bacillus subtilis such as multidrug resistance proteins 1 (Bmr1) and 2 (Bmr2), and from Staphylococcus aureus such as quinolone resistance protein NorA. The family also includes Escherichia coli arabinose efflux transporters YfcJ and YhhS. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The SLC18 transporter family includes vesicular monoamine transporters (VAT1 and VAT2), vesicular acetylcholine transporter (VAChT), and SLC18B1, which is proposed to be a vesicular polyamine transporter (VPAT). The MdtG/SLC18 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.
Pssm-ID: 340883 [Multi-domain] Cd Length: 375 Bit Score: 43.72 E-value: 1.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 7 FRNAYYRFASSYSFLFFISWSLWWSLYAIWLKGHLGLTGTELGTLYSVNQFTSILFMMFYGIVQDKLGLKKPLIWCMsFI 86
Cdd:cd17325 196 LRDRRLLALFLAIFVLAFAFGALEPFLPLYAAELGGLSPAQIGLLFGAQGLASALSQPPAGKLSDRIGRKPLILIGL-LL 274
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 87 LVLTGPFMIYVYEPLLqsnfsvgLILGALFFGLGYLAGCGLLDSFTEKMARNFHFE--YGTARAWGSFGYAIGAFFAG-I 163
Cdd:cd17325 275 SAVALLLLPLATSFWL-------LLLLLALLGLGLGLVFPATLALLADIVPPEGRGtaMGLFNTAFSLGMVLGPLLGGfL 347
|
170 180
....*....|....*....|...
gi 15832495 164 FFSISPHINFWLVSLFGAVFMMI 186
Cdd:cd17325 348 YDAFGFATPFLAAAALLLLAAVL 370
|
|
| UhpC |
COG2271 |
Sugar phosphate permease [Carbohydrate transport and metabolism]; |
30-403 |
2.38e-04 |
|
Sugar phosphate permease [Carbohydrate transport and metabolism];
Pssm-ID: 441872 [Multi-domain] Cd Length: 363 Bit Score: 42.93 E-value: 2.38e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 30 WSLYAIWLKGHLGLTGTELGTLYSVNQFTSILFMMFYGIVQDKLGLKKPLIWCMsFILVLTGPFMIYVYEPLLqsnFSVG 109
Cdd:COG2271 29 LSVAAPPLQADLGLSAAQLGLLASAFFLGYALGQIPAGLLADRFGRRRVLAIGL-LLWGLATLLFGFATSFWQ---LLLL 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 110 LILGALFFGLGYLAGCGLL-DSFTEKmarnfhfEYGTARAWGSFGYAIGAFFAGIFFSisphinfWLVSLFGAVFMMInm 188
Cdd:COG2271 105 RFLLGLGEAGFFPAALKLIaEWFPPK-------ERGRALGIFNAGGPLGGALAPPLLG-------WLLAAFGWRAAFL-- 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 189 cfkdkdhqcVAADAGGVkkedfIAVFkdrNFWVFVIFIVGTWSFYNIFdQQLFPVFyagLFESHDVGTRLYGYLNSFQVV 268
Cdd:COG2271 169 ---------ILGLPGLL-----LALL---RFWLLALAYFLVYFALYGF-LTWLPTY---LVEVRGLSLAQAGLLLSLPFL 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 269 LEALCMAIIPFFVNRVG--PKNALLIGVVIMALRILSCALFVNPWIISLVKLLHAIEVPLCVISVFKYSVANFDKRLSST 346
Cdd:COG2271 228 AGIVGSLLGGWLSDRLGrrRKLVLAIGLLLAALALLLLALLPSPALAIALLFLAGFGLGGAFGLLWALAAELFPKKARGT 307
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 15832495 347 IF-LIGFqiASSLGIVLLSTPTGILFDHAGYQTVFFAISGIVCLMLLFGIFFLSKKRE 403
Cdd:COG2271 308 ASgLVNT--FGFLGGALGPLLVGYLLDATGYQAAFLLLAALALLAALLALLLLRETRK 363
|
|
| Nuc_H_symport |
pfam03825 |
Nucleoside H+ symporter; |
19-347 |
4.28e-04 |
|
Nucleoside H+ symporter;
Pssm-ID: 461066 [Multi-domain] Cd Length: 399 Bit Score: 42.07 E-value: 4.28e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 19 SFLFFISWSLWWS-LYAIWL-KGHLGLTGTELGTLYSVNQFTSILFMMFYGIVQDK-LGLKKPLIWCMsFILVLTGPFMI 95
Cdd:pfam03825 8 KVMMFLQFFIWGAwLVTLGSyMFVTGFDGASIGAVYSSLGIAAIFMPALLGIIADRwFSAERVLAVCH-LIGAITLFMAA 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 96 YVYEPllqsnfsVGLILGALFFGLGYLAGCGLLDSFTEKMARNFHFEYGTARAWGSFGYAIGA----FFAGIFFSISP-H 170
Cdd:pfam03825 87 QVTTF-------EAFFLVILVNSLAYMPTLALTNSIAFANLQDPVTDFPPIRVWGTIGWIMASwpfvMWVVSLAGFELsH 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 171 INFWLVSLFGAVFMMINMCFKDKDHQCVAADAGGVKK-EDFIAVFKDRNFWVFVIFivgtwSFYNIFDQQLFPVFYAGLF 249
Cdd:pfam03825 160 MQLLIAAGLSALLVLFALTLPHTPAKQKANQSWTTLLgLDAFALLKNKRMAVFFIF-----SFLLGAELQIYNVFANTFL 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 250 ESHD-VGTRLYGYLNSFQVVLEALCMAIIPFFVNRVGPKNALLIGVVIMALRILSCALFVNPWIISLVKLLHAIEVPLCV 328
Cdd:pfam03825 235 TSFDkFIVKHASIIMSLGQISEILFMLTLPFFLKRFGIKNVMLIGIVAWALRFAFFAYGADPTPFGTALLLLSMIVHGVA 314
|
330 340
....*....|....*....|
gi 15832495 329 ISVFKYSVANF-DKRLSSTI 347
Cdd:pfam03825 315 YDFFNITGYIFvDKEVPPAI 334
|
|
| NarK |
COG2223 |
Nitrate/nitrite transporter NarK [Inorganic ion transport and metabolism]; |
7-200 |
7.22e-04 |
|
Nitrate/nitrite transporter NarK [Inorganic ion transport and metabolism];
Pssm-ID: 441825 [Multi-domain] Cd Length: 392 Bit Score: 41.40 E-value: 7.22e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 7 FRNAYYRFASSYSFLFFISWSLWWSLYAIWLKGHLGLTGTELGTLYSVNQFTSILFMMFYGIVQDKLGLKKPLIWCMSFI 86
Cdd:COG2223 202 LRDPRFWLLSLLYFGTFGSFIGFSSWLPPYLVDQFGLSAATAGLLAALFALLGALGRPLGGWLSDRIGGRRVLLIVFALM 281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 87 LVLTGPFmiyvyePLLQSNFsVGLILGALFFGLGYLAGCGLLDSFTEKMARNFHfeYGTARAWGSFGYAIGAFFAGIFFS 166
Cdd:COG2223 282 ALGLLLL------ALALGSL-WLFLVLFLLLGLALGGGNGAVFALVPDIFPTKN--AGAVYGLVGAAGGLGGFLGPLLFG 352
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 15832495 167 I------SPHINFWLVSLFGAVFMMINMCFKDKDHQCVAA 200
Cdd:COG2223 353 AlldatgSYTAAFLVFAVLALVALVLTLLLYRRPRRAAAA 392
|
|
| MFS_MMR_MDR_like |
cd17504 |
Methylenomycin A resistance protein (also called MMR peptide)-like multidrug resistance (MDR) ... |
279-396 |
3.73e-03 |
|
Methylenomycin A resistance protein (also called MMR peptide)-like multidrug resistance (MDR) transporters of the Major Facilitator Superfamily; This subfamily is composed of putative multidrug resistance (MDR) transporters including Chlamydia trachomatis antiseptic resistance protein QacA_2, and Serratia sp. DD3 Bmr3. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. This subfamily belongs to the Methylenomycin A resistance protein (also called MMR peptide) and similar multidrug resistance (MDR) transporters (MMR-like MDR transporter) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.
Pssm-ID: 341047 [Multi-domain] Cd Length: 371 Bit Score: 39.10 E-value: 3.73e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 279 FFVNRVGPKNALLIGVVIMALRILSCALFV-NPWIISLVKLLHAIEVPLCVISVFKYSVANFDKR-------LSSTIFLI 350
Cdd:cd17504 239 RLIARVGPRRVLLIGLVISAVGLLLLALLHsSLWALVVALLLIGIGLGLAFASLPNIVVESVPPDrtgiatgMNTVLRTI 318
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 15832495 351 GFQIASSLGIVLLSTPTGILF-----DHAGYQTVFFAISGIVCLMLLFGIF 396
Cdd:cd17504 319 GSAIGPAIAGAILTTYTVSITsggvpTEGAYVLAFLIGAALALAALLLSLL 369
|
|
| MFS_ShiA_like |
cd17369 |
Shikimate transporter and similar proteins of the Major Facilitator Superfamily; This ... |
13-182 |
3.80e-03 |
|
Shikimate transporter and similar proteins of the Major Facilitator Superfamily; This subfamily is composed of Escherichia coli shikimate transporter (ShiA), inner membrane metabolite transport protein YhjE, and other putative metabolite transporters. ShiA is involved in the uptake of shikimate, an aromatic compound involved in siderophore biosynthesis. It has been suggested that YhjE may mediate the uptake of osmoprotectants. The ShiA-like subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.
Pssm-ID: 340927 [Multi-domain] Cd Length: 408 Bit Score: 39.43 E-value: 3.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 13 RFASSYSFLFFISWSLwwslyaIWLKGHLGLTGTELGTLYSVNQFTSILFMMFYGIVQDKLGLKKPLIWCMSFILVLTGP 92
Cdd:cd17369 237 RLAENVLFYLFTTFAL------SYATQTLGVDRSTVLLAVLIASVVAAITIPLFGWLSDRVGRRPVYLAGALLAALFAFP 310
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 93 FMiyvyePLLQSNFSVGLILGALF-FGLGYLAGCGLLDSFtekMARNFHFEYGTARAwgSFGYAIGAFFAGiffSISPHI 171
Cdd:cd17369 311 FF-----WLLDTGSTWLIVLAAVVvLGVLHGMMYGPQAAF---LAELFPTRVRYTGA--SLGYQLGAILGG---GFAPLI 377
|
170
....*....|.
gi 15832495 172 NFWLVSLFGAV 182
Cdd:cd17369 378 ATALVAATGSW 388
|
|
| MFS_LmrB_MDR_like |
cd17503 |
Bacillus subtilis lincomycin resistance protein (LmrB) and similar multidrug resistance (MDR) ... |
213-365 |
4.89e-03 |
|
Bacillus subtilis lincomycin resistance protein (LmrB) and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily; This subfamily is composed of multidrug resistance (MDR) transporters including Bacillus subtilis lincomycin resistance protein LmrB, and several proteins from Escherichia coli such as the putative MDR transporters EmrB, MdtD, and YieQ. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. For example, MMR confers resistance to the epoxide antibiotic methylenomycin. This subfamily belongs to the Methylenomycin A resistance protein (also called MMR peptide) and similar multidrug resistance (MDR) transporters (MMR-like MDR transporter) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.
Pssm-ID: 341046 [Multi-domain] Cd Length: 380 Bit Score: 38.71 E-value: 4.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 213 VFKDRNFWVFVI--FIVGTWSFYNIFdqqLFPVFyagLFESHDVGTRLYGYLNSFQVVLEALCMAIIPFFVNRVGPKNAL 290
Cdd:cd17503 174 LFKDRNFTLGLLlsFLLGLGLFGAMF---LLPLY---LQNVLGYSAFESGLVLAPGGLASAILSPLVGRLLDKFGPRLLL 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 291 LIGVVIMALRILSCALFV---NPWIISLVKLLHAIEVPLCVISVFKYSVANFDKRLS---STIFLIGFQIASSLGIVLLS 364
Cdd:cd17503 248 LAGLLLLALGTLLLAFLTpdtSLWLIILPLFIRGLGMGLVFMPLNTLALNSLPPEQIgdaTALFNTIRQLGGSIGTALLA 327
|
.
gi 15832495 365 T 365
Cdd:cd17503 328 T 328
|
|
| AraJ |
COG2814 |
Predicted arabinose efflux permease AraJ, MFS family [Carbohydrate transport and metabolism]; |
7-123 |
7.86e-03 |
|
Predicted arabinose efflux permease AraJ, MFS family [Carbohydrate transport and metabolism];
Pssm-ID: 442063 [Multi-domain] Cd Length: 348 Bit Score: 38.03 E-value: 7.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15832495 7 FRNAYYRFASSYSFLFFISWSLWWSLYAIWLKGHLGLTGTELGTLYSVNQFTSILFMMFYGIVQDKLGLKKPLIWCMSFI 86
Cdd:COG2814 204 LRRPRLLLLLLLAFLLGFGFFALFTYLPLYLQEVLGLSASAAGLLLALFGLGGVLGALLAGRLADRFGRRRLLLIGLLLL 283
|
90 100 110
....*....|....*....|....*....|....*..
gi 15832495 87 LVLTGPFMIyvyepllqSNFSVGLILGALFFGLGYLA 123
Cdd:COG2814 284 ALGLLLLAL--------AGSLWLLLLALFLLGFGFGL 312
|
|
| |
