|
Name |
Accession |
Description |
Interval |
E-value |
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
130-454 |
2.92e-58 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 194.74 E-value: 2.92e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 130 ANTEMVQATRTVVFSRGQQLQREIAERGQYFGWQSLVLFLVSLVMVLLFTRMIIGPVKNIERMINRLGEGRSLGNSVSFS 209
Cdd:COG0642 5 LLLLVLLLLLLLLLLLALLLLLLLLLLLALLLLLALLLLLLLLLLLLLLLALALLALLLLLLLLLLLLLLLLLLLLLLLL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 210 GPSELRSVGQRILWLSERLSWLESQRHQFLRHLSHELKTPLASMREGTELLADQVvgplTPEQKEVVSILDSSSRNLQKL 289
Cdd:COG0642 85 LLLLLLLLLLLLLALLLLLEEANEAKSRFLANVSHELRTPLTAIRGYLELLLEEL----DEEQREYLETILRSADRLLRL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 290 IEQLLDYNRKQADS-AVELDNVELAPLVETVVSAHSLPARAKMMHTDVDLKATAC--LAEPMLLMSVLDNLYSNAVHYGA 366
Cdd:COG0642 161 INDLLDLSRLEAGKlELEPEPVDLAELLEEVVELFRPLAEEKGIELELDLPDDLPtvRGDPDRLRQVLLNLLSNAIKYTP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 367 ESGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFQGSHQRKGavKGSGLGLSIARDCIRRMQGELYLVDESGQD 446
Cdd:COG0642 241 EGGTVTVSVRREGDRVRISVEDTGPGIPPEDLERIFEPFFRTDPSRRG--GGTGLGLAIVKRIVELHGGTIEVESEPGKG 318
|
....*...
gi 1447699692 447 VCFRIELP 454
Cdd:COG0642 319 TTFTVTLP 326
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
231-454 |
1.13e-56 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 187.42 E-value: 1.13e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 231 LESQRHQFLRHLSHELKTPLASMREGTELLADQVvGPLTPEQKEVVSILDSSSRNLQKLIEQLLDYNRKQADS-AVELDN 309
Cdd:COG2205 12 LERLKSEFLANVSHELRTPLTSILGAAELLLDEE-DLSPEERRELLEIIRESAERLLRLIEDLLDLSRLESGKlSLELEP 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 310 VELAPLVETVVSAHSLPARAKMMHTDVDLKATACLAE--PMLLMSVLDNLYSNAVHYGAESGNICLRSSLHGARVYIDVI 387
Cdd:COG2205 91 VDLAELLEEAVEELRPLAEEKGIRLELDLPPELPLVYadPELLEQVLANLLDNAIKYSPPGGTITISARREGDGVRISVS 170
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1447699692 388 NTGTPIPQEERAMIFEPFFQGSHQRKgaVKGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIELP 454
Cdd:COG2205 171 DNGPGIPEEELERIFERFYRGDNSRG--EGGTGLGLAIVKRIVEAHGGTIWVESEPGGGTTFTVTLP 235
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
129-458 |
1.97e-54 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 186.68 E-value: 1.97e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 129 SANTEMVQATRTVVFSRGQQLQREIAERGQYFGWQSLVLFLVSLVMVLLFTRMIIGPVKNIERMINRLGEGRSLGNSVSF 208
Cdd:COG5002 63 LLLLALLLLLLLLLLLLALALLLLALLLLLLLLLLLLALLILLLLLALLILLAALLLLLSELLLLLLLLGRLSLRLSALL 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 209 SGPSELRSVGQRIlwlsERLSWLESQRHQFLRHLSHELKTPLASMREGTELLADQVVGPlTPEQKEVVSILDSSSRNLQK 288
Cdd:COG5002 143 LGLLLLAAVERDI----TELERLEQMRREFVANVSHELRTPLTSIRGYLELLLDGAADD-PEERREYLEIILEEAERLSR 217
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 289 LIEQLLDYNRKQADSA-VELDNVELAPLVETVVSAHSLPARAKMMHTDVDLKATACL--AEPMLLMSVLDNLYSNAVHYG 365
Cdd:COG5002 218 LVNDLLDLSRLESGELkLEKEPVDLAELLEEVVEELRPLAEEKGIELELDLPEDPLLvlGDPDRLEQVLTNLLDNAIKYT 297
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 366 AESGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFQGSHQRKGAVKGSGLGLSIARDCIRRMQGELYLVDESGQ 445
Cdd:COG5002 298 PEGGTITVSLREEDDQVRISVRDTGIGIPEEDLPRIFERFYRVDKSRSRETGGTGLGLAIVKHIVEAHGGRIWVESEPGK 377
|
330
....*....|...
gi 1447699692 446 DVCFRIELPSSKN 458
Cdd:COG5002 378 GTTFTITLPLARE 390
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
141-454 |
1.08e-33 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 129.92 E-value: 1.08e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 141 VVFSRGQQLQREIAERGQYFGWQSLVLFLVSLVMVLLFTRMIIGPVKNIERMINRLGEGRSLGNSVSFSGPSELRSVGQR 220
Cdd:COG4191 36 LLLLLALLLALLALLLLLLLLLLLLLLELLLLLLALLGGLLRLLLLLGLLLLLLLEALLLLLLAALDAEENAELEELERD 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 221 ILWLSERLSWLESQRHQfLRH-------------LSHELKTPLASMREGTELLADQVVGPLTPEQ-KEVVSILDSSSRNL 286
Cdd:COG4191 116 ITELERAEEELRELQEQ-LVQseklaalgelaagIAHEINNPLAAILGNAELLRRRLEDEPDPEElREALERILEGAERA 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 287 QKLIEQLLDYNRKQADSAVELDnveLAPLVETVVS--AHSLPARAKMMHTDVDLKATACLAEPMLLMSVLDNLYSNAVH- 363
Cdd:COG4191 195 AEIVRSLRAFSRRDEEEREPVD---LNELIDEALEllRPRLKARGIEVELDLPPDLPPVLGDPGQLEQVLLNLLINAIDa 271
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 364 -YGAESGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFQgshqRKGAVKGSGLGLSIARDCIRRMQGELYLVDE 442
Cdd:COG4191 272 mEEGEGGRITISTRREGDYVVISVRDNGPGIPPEVLERIFEPFFT----TKPVGKGTGLGLSISYGIVEKHGGRIEVESE 347
|
330
....*....|..
gi 1447699692 443 SGQDVCFRIELP 454
Cdd:COG4191 348 PGGGTTFTITLP 359
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
160-454 |
1.25e-33 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 131.89 E-value: 1.25e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 160 FGWQSLVLFLVSLVMVLLFTRMIIGPVKNIERMINRLGEGRSLgnSVSFSGPSELRSVGQRilwlserlswLESQRHQ-- 237
Cdd:PRK11100 184 ILWAGALLLGIALLIGAGVVWWLNRSIRRLTRYADAVTEGKPV--PLPKLGSSELRELAQA----------LESMRVKle 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 238 -------FLRHLSHELKTPLASMREGTELLADqvvgPLTPEQKE--VVSILDSSSRnLQKLIEQLLDY----NRKQADsa 304
Cdd:PRK11100 252 gkayveqYVQTLTHELKSPLAAIRGAAELLQE----DPPPEDRArfTGNILTQSAR-LQQLIDRLLELarleQRQELE-- 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 305 vELDNVELAPLVETVVSAHSLPARAKMMHTDVDLKATACLAEPMLLMSVLDNLYSNAVHYGAESGNICLRSSLHGARVYI 384
Cdd:PRK11100 325 -VLEPVALAALLEELVEAREAQAAAKGITLRLRPDDARVLGDPFLLRQALGNLLDNAIDFSPEGGTITLSAEVDGEQVAL 403
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1447699692 385 DVINTGTPIPQEERAMIFEPFFqgSHQRK-GAVKGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIELP 454
Cdd:PRK11100 404 SVEDQGPGIPDYALPRIFERFY--SLPRPaNGRKSTGLGLAFVREVARLHGGEVTLRNRPEGGVLATLTLP 472
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
213-454 |
4.12e-29 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 117.25 E-value: 4.12e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 213 ELRSVGQRiLWLSERLswLESQRHQFLRHLS----HELKTPLASMREGTELLADQVVGPltpEQKEVVSILDSSSRNLQK 288
Cdd:COG3852 112 VLRDITER-KRLEREL--RRAEKLAAVGELAaglaHEIRNPLTGIRGAAQLLERELPDD---ELREYTQLIIEEADRLNN 185
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 289 LIEQLLDYNRKQAdsaVELDNVELAPLVETVVS-AHSLPARAKMMHTDVDLKATACLAEPMLLMSVLDNLYSNAVHYGAE 367
Cdd:COG3852 186 LVDRLLSFSRPRP---PEREPVNLHEVLERVLElLRAEAPKNIRIVRDYDPSLPEVLGDPDQLIQVLLNLVRNAAEAMPE 262
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 368 SGNICLRSSL----------HGARVYIDVINTGTPIPQEERAMIFEPFFQGshqrKGavKGSGLGLSIARDCIRRMQGEL 437
Cdd:COG3852 263 GGTITIRTRVerqvtlgglrPRLYVRIEVIDNGPGIPEEILDRIFEPFFTT----KE--KGTGLGLAIVQKIVEQHGGTI 336
|
250
....*....|....*..
gi 1447699692 438 YLVDESGQDVCFRIELP 454
Cdd:COG3852 337 EVESEPGKGTTFRIYLP 353
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
231-454 |
6.37e-29 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 117.76 E-value: 6.37e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 231 LESQR----HQFLRHLSHELKTPLASMREGTELLADQVVGPLTPEQ---KEVVSILDSSSRNLQKLIEQLLDYNRKqadS 303
Cdd:COG5000 193 LRAERlaawGELARRIAHEIKNPLTPIQLSAERLRRKLADKLEEDRedlERALDTIIRQVDRLKRIVDEFLDFARL---P 269
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 304 AVELDNVELAPLVETVVSAHSLPARAKMMHTDVDLKATACLAE--PMLLMSVLDNLYSNAVHYGAESGNICLRSSLHGAR 381
Cdd:COG5000 270 EPQLEPVDLNELLREVLALYEPALKEKDIRLELDLDPDLPEVLadRDQLEQVLINLLKNAIEAIEEGGEIEVSTRREDGR 349
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1447699692 382 VYIDVINTGTPIPQEERAMIFEPFFqgSHQRkgavKGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIELP 454
Cdd:COG5000 350 VRIEVSDNGPGIPEEVLERIFEPFF--TTKP----KGTGLGLAIVKKIVEEHGGTIELESRPGGGTTFTIRLP 416
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
345-454 |
1.01e-27 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 106.19 E-value: 1.01e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 345 AEPMLLMSVLDNLYSNAVHYGAESGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFQGShQRKGAVKGSGLGLS 424
Cdd:smart00387 1 GDPDRLRQVLSNLLDNAIKYTPEGGRITVTLERDGDHVEITVEDNGPGIPPEDLEKIFEPFFRTD-KRSRKIGGTGLGLS 79
|
90 100 110
....*....|....*....|....*....|
gi 1447699692 425 IARDCIRRMQGELYLVDESGQDVCFRIELP 454
Cdd:smart00387 80 IVKKLVELHGGEISVESEPGGGTTFTITLP 109
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
240-454 |
1.04e-25 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 110.50 E-value: 1.04e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 240 RHL---SHELKTPLASMREGTELLADqvvGPLTPEQKEVVSILDSSSRNLQKLIEQLLDYNRKQADS-AVELDNVELAPL 315
Cdd:PRK15347 400 EHLttiSHEIRTPLNGVLGALELLQN---TPLTAEQMDLADTARQCTLSLLAIINNLLDFSRIESGQmTLSLEETALLPL 476
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 316 VETVVSAHSLPARAK--MMHT----DVDLKAtacLAEPMLLMSVLDNLYSNAVHYgAESGNICLRSSLHGARVYIDVINT 389
Cdd:PRK15347 477 LDQAMLTIQGPAQSKslTLRTfvgaHVPLYL---HLDSLRLRQILVNLLGNAVKF-TETGGIRLRVKRHEQQLCFTVEDT 552
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1447699692 390 GTPIPQEERAMIFEPFFQGSHQRKGavkgSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIELP 454
Cdd:PRK15347 553 GCGIDIQQQQQIFTPFYQADTHSQG----TGLGLTIASSLAKMMGGELTLFSTPGVGSCFSLVLP 613
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
15-454 |
1.21e-23 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 103.33 E-value: 1.21e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 15 AWQAWQSLNALSDQAALVNRTTLIDARRSEAMTNAALEMERSYRQYCVLDDPTLAKVYQSQRKRYSEMLDAHAGVLPDDK 94
Cdd:COG4251 49 RLLLLLLLSLLALLLLLLLLLLLLLVLAALALLLLLLLLELALVLLALLLVLLLLLALLLLLALLLLLELLLLLLALLLL 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 95 LYQALRQDLNNLAQLQCNNSGPDAAAAARLEAFASANTEMVQATRTVVFSRGQQLQREIAERGQYFGWQSLVLFLVSLVm 174
Cdd:COG4251 129 LLLLALLLLEELALLRLALALLLLLLLLLLLLLLLLALILALLLAALAELELLLLLLLVLLLLLLLLLLLLLLLLRLLL- 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 175 VLLFTRMIIGPVKNIERMINRLGEGRSLGNSVSFSGPSELRSVGQRILWLSERLSWLESQRHQFLRHL------------ 242
Cdd:COG4251 208 ELLLLLEAELLLSLGGGLGLLLLLLLLLVLLLLLILLLLLLILVLELLELRLELEELEEELEERTAELersneeleqfay 287
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 243 --SHELKTPLASMREGTELLADQVVGPLTPEQKEVVSILDSSSRNLQKLIEQLLDYNRkQADSAVELDNVELAPLVETVV 320
Cdd:COG4251 288 vaSHDLREPLRKISGFSQLLEEDYGDKLDEEGREYLERIRDAAERMQALIDDLLAYSR-VGRQELEFEPVDLNELLEEVL 366
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 321 SAHSLPARAKMMHTDVDlKATACLAEPMLLMSVLDNLYSNAVHYGA--ESGNICLRSSLHGARVYIDVINTGTPIPQEER 398
Cdd:COG4251 367 EDLEPRIEERGAEIEVG-PLPTVRGDPTLLRQVFQNLISNAIKYSRpgEPPRIEIGAEREGGEWVFSVRDNGIGIDPEYA 445
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*....
gi 1447699692 399 AMIFEPFfqgshQR---KGAVKGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIELP 454
Cdd:COG4251 446 EKIFEIF-----QRlhsRDEYEGTGIGLAIVKKIVERHGGRIWVESEPGEGATFYFTLP 499
|
|
| cpxA |
PRK09470 |
envelope stress sensor histidine kinase CpxA; |
165-435 |
6.59e-22 |
|
envelope stress sensor histidine kinase CpxA;
Pssm-ID: 236532 [Multi-domain] Cd Length: 461 Bit Score: 97.70 E-value: 6.59e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 165 LVLFLVSLVMVLLFTRMIIGPVKNIERMINRLGEGRSLGNSVSFSGPSELRSVGQRILWLSERLSWLESQRHQFLRHLSH 244
Cdd:PRK09470 173 LVTMLVSTPLLLWLAWSLAKPARKLKNAADEVAQGNLRQHPELETGPQEFRQAGASFNQMVTALERMMTSQQRLLSDISH 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 245 ELKTPLASMREGTELLADQVvGpltpEQKEVVSIlDSSSRNLQKLIEQLLDYNRKQADSAVELDNVELAPLVETVVSAHS 324
Cdd:PRK09470 253 ELRTPLTRLQLATALLRRRQ-G----ESKELERI-ETEAQRLDSMINDLLVLSRNQQKNHLERETFKANSLWSEVLEDAK 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 325 LPA--RAKMMHTDVDLKATACLAEPMLLMSVLDNLYSNAVHYGAESgnICLRSSLHGARVYIDVINTGTPIPQEERAMIF 402
Cdd:PRK09470 327 FEAeqMGKSLTVSAPPGPWPINGNPNALASALENIVRNALRYSHTK--IEVAFSVDKDGLTITVDDDGPGVPEEEREQIF 404
|
250 260 270
....*....|....*....|....*....|...
gi 1447699692 403 EPFFQGSHQRKGAVKGSGLGLSIARDCIRRMQG 435
Cdd:PRK09470 405 RPFYRVDEARDRESGGTGLGLAIVENAIQQHRG 437
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
347-454 |
1.24e-21 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 89.35 E-value: 1.24e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 347 PMLLMSVLDNLYSNAVHYGAESGNICLRSSlHGARVYIDVINTGTPIPQEERAMIFEPFFQGSHQRKGavkGSGLGLSIA 426
Cdd:pfam02518 3 ELRLRQVLSNLLDNALKHAAKAGEITVTLS-EGGELTLTVEDNGIGIPPEDLPRIFEPFSTADKRGGG---GTGLGLSIV 78
|
90 100
....*....|....*....|....*...
gi 1447699692 427 RDCIRRMQGELYLVDESGQDVCFRIELP 454
Cdd:pfam02518 79 RKLVELLGGTITVESEPGGGTTVTLTLP 106
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
238-454 |
1.13e-20 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 95.36 E-value: 1.13e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 238 FLRHLSHELKTPLASMREGTELLADQvvgPLTPEQKEVVSILDSSSRNLQKLIEQLLDYNRKQADS-AVELDNVELAP-- 314
Cdd:PRK11466 447 FLAAMSHEIRTPLYGILGTAQLLADN---PALNAQRDDLRAITDSGESLLTILNDILDYSAIEAGGkNVSVSDEPFEPrp 523
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 315 LVETVVSAHSLPARAKMMHTDVDLK---ATACLAEPMLLMSVLDNLYSNAVHYgAESGNICLRSSLHGARVYIDVINTGT 391
Cdd:PRK11466 524 LLESTLQLMSGRVKGRPIRLATDIAddlPTALMGDPRRIRQVITNLLSNALRF-TDEGSIVLRSRTDGEQWLVEVEDSGC 602
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1447699692 392 PIPQEERAMIFEPFFQGSHQRkgavKGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIELP 454
Cdd:PRK11466 603 GIDPAKLAEIFQPFVQVSGKR----GGTGLGLTISSRLAQAMGGELSATSTPEVGSCFCLRLP 661
|
|
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
167-454 |
1.89e-19 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 90.35 E-value: 1.89e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 167 LFLVSLVMVLL-------FTRMIIGPVKNIERMINRLGEGrSLGNSVSFSGPSELRSVGQRILWLSERLSWLESQRHQFL 239
Cdd:PRK09467 155 LFRYTLAIGLLsvaggwlFIRIQNRPLVALEHAALQVGKG-EIPPPLREYGASEVRSVTRAFNQMAAGIKQLEDDRTLLM 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 240 RHLSHELKTPLASMREGTELLAdqvvgpltPEQ---KEvvSIL-DSSSRNlqKLIEQLLDYNRKQADSAVELdnVELAPL 315
Cdd:PRK09467 234 AGVSHDLRTPLTRIRLATEMMS--------EEDgylAE--SINkDIEECN--AIIEQFIDYLRTGQEMPMEM--ADLNAL 299
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 316 VETVVSAHSlpARAKMMHTDVDLKATACLAEPMLLMSVLDNLYSNAVHYGaeSGNICLRSSLHGARVYIDVINTGTPIPQ 395
Cdd:PRK09467 300 LGEVIAAES--GYEREIETALQPGPIEVPMNPIAIKRALANLVVNAARYG--NGWIKVSSGTEGKRAWFQVEDDGPGIPP 375
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 1447699692 396 EERAMIFEPFFQGSHQRKGAvkGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIELP 454
Cdd:PRK09467 376 EQLKHLFQPFTRGDSARGSS--GTGLGLAIVKRIVDQHNGKVELGNSEEGGLSARAWLP 432
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
347-454 |
4.59e-19 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 82.08 E-value: 4.59e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 347 PMLLMSVLDNLYSNAVHYGAESGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFqgshQRKGAVKGSGLGLSIA 426
Cdd:cd16943 1 PSQLNQVLLNLLVNAAQAMEGRGRITIRTWAHVDQVLIEVEDTGSGIDPEILGRIFDPFF----TTKPVGEGTGLGLSLS 76
|
90 100
....*....|....*....|....*...
gi 1447699692 427 RDCIRRMQGELYLVDESGQDVCFRIELP 454
Cdd:cd16943 77 YRIIQKHGGTIRVASVPGGGTRFTIILP 104
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
169-454 |
6.79e-19 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 88.92 E-value: 6.79e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 169 LVSLVMVLLFTRMIIGPVKNIERMINRLGEGrSLGNSVSFSGPSELRSVGQRILWLSERLSWLESQRHQFLRHLSHELKT 248
Cdd:PRK10549 175 LLAALATFLLARGLLAPVKRLVEGTHKLAAG-DFTTRVTPTSRDELGRLAQDFNQLASTLEKNEQMRRDFMADISHELRT 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 249 PLASMREGTELLADQVVGPlTPEQkevVSILDSSSRNLQKLIEQL----------LDYnRKQAdsaveldnVELAPLVET 318
Cdd:PRK10549 254 PLAVLRGELEAIQDGVRKF-TPES---VASLQAEVGTLTKLVDDLhqlslsdegaLAY-RKTP--------VDLVPLLEV 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 319 VVSAHSLPARAKMMHTDVDLKATACL-AEPMLLMSVLDNLYSNAVHYGAESGNICLRSSLHGARVYIDVINTGTPIPQEE 397
Cdd:PRK10549 321 AGGAFRERFASRGLTLQLSLPDSATVfGDPDRLMQLFNNLLENSLRYTDSGGSLHISAEQRDKTLRLTFADSAPGVSDEQ 400
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 1447699692 398 RAMIFEPFFQGSHQRKGAVKGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIELP 454
Cdd:PRK10549 401 LQKLFERFYRTEGSRNRASGGSGLGLAICLNIVEAHNGRIIAAHSPFGGVSITVELP 457
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
244-454 |
1.02e-18 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 88.87 E-value: 1.02e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 244 HELKTPLASMREGTELLADQVVGPLTPEQ-----KEVvsildsssRNLQKLIEQLLDYNRKqadSAVELDNVELAPLVET 318
Cdd:PRK11360 399 HEIRNPLTAIRGYVQIWRQQTSDPPSQEYlsvvlREV--------DRLNKVIDQLLEFSRP---RESQWQPVSLNALVEE 467
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 319 VV-----SAHSlpARAKMmHTDVDLKATACLAEPMLLMSVLDNLYSNAVHYGAESGNICLRSSLHGA-RVYIDVINTGTP 392
Cdd:PRK11360 468 VLqlfqtAGVQ--ARVDF-ETELDNELPPIWADPELLKQVLLNILINAVQAISARGKIRIRTWQYSDgQVAVSIEDNGCG 544
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1447699692 393 IPQEERAMIFEPFFQGShqrkgaVKGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIELP 454
Cdd:PRK11360 545 IDPELLKKIFDPFFTTK------AKGTGLGLALSQRIINAHGGDIEVESEPGVGTTFTLYLP 600
|
|
| cztS_silS_copS |
TIGR01386 |
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain ... |
162-454 |
1.62e-18 |
|
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.
Pssm-ID: 273593 [Multi-domain] Cd Length: 457 Bit Score: 87.44 E-value: 1.62e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 162 WQSLVLFLVSLVMVLLFTRMIIGPVKNIERMINRLgEGRSLGNSVSFSG-PSELRSVGQRILWLSERLSWLESQRHQFLR 240
Cdd:TIGR01386 168 LIAVLLVLLTALLGWWITRLGLEPLRRLSAVAARI-SPESLDQRLDPSRaPAELRELAQSFNAMLGRLEDAFQRLSQFSA 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 241 HLSHELKTPLASMREGTELLADQvvgPLTpeQKEVVSILDSSSRNLQKL---IEQLLDYNR-KQADSAVELDNVELAPLV 316
Cdd:TIGR01386 247 DLAHELRTPLTNLLGQTQVALSQ---PRT--GEEYREVLESNLEELERLsrmVSDMLFLARaDNGQLALERVRLDLAAEL 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 317 ETVVSAHSLPARAKMMHTDVDLKATAcLAEPMLLMSVLDNLYSNAVHYGAESGNICLRSSLHGARVYIDVINTGTPIPQE 396
Cdd:TIGR01386 322 AKVAEYFEPLAEERGVRIRVEGEGLV-RGDPQMFRRAISNLLSNALRHTPDGGTITVRIERRSDEVRVSVSNPGPGIPPE 400
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 1447699692 397 ERAMIFEPFFQGSHQRKGAVKGSGLGLSIARDCIRRMQGELYlVDESGQDVCFRIELP 454
Cdd:TIGR01386 401 HLSRLFDRFYRVDPARSNSGEGTGLGLAIVRSIMEAHGGRAS-AESPDGKTRFILRFP 457
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
353-454 |
2.24e-18 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 80.23 E-value: 2.24e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 353 VLDNLYSNAVHYGAEsGNICLRSSL-----HGARVYIDVINTGTPIPQEERAMIFEPFFQGSHQRKGAVKGSGLGLSIAR 427
Cdd:cd16922 4 ILLNLLGNAIKFTEE-GEVTLRVSLeeeeeDGVQLRFSVEDTGIGIPEEQQARLFEPFSQADSSTTRKYGGTGLGLAISK 82
|
90 100
....*....|....*....|....*..
gi 1447699692 428 DCIRRMQGELYLVDESGQDVCFRIELP 454
Cdd:cd16922 83 KLVELMGGDISVESEPGQGSTFTFTLP 109
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
235-454 |
5.15e-18 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 87.10 E-value: 5.15e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 235 RHQFLRHLSHELKTPLASMREGTELLADQvvgPLTPEQK-EVVSILDSSSRNLQKLIEQLLDYNRkqadsaVELDNVELA 313
Cdd:PRK09959 712 KSQFLATMSHEIRTPISSIMGFLELLSGS---GLSKEQRvEAISLAYATGQSLLGLIGEILDVDK------IESGNYQLQ 782
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 314 PL---VETVV--SAHSLPARAKMMHTDVDLKAT-----ACLAEPMLLMSVLDNLYSNAVHYGAEsGNICLRSSL-----H 378
Cdd:PRK09959 783 PQwvdIPTLVqnTCHSFGAIAASKSIALSCSSTfpdhyLVKIDPQAFKQVLSNLLSNALKFTTE-GAVKITTSLghiddN 861
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1447699692 379 GARVYIDVINTGTPIPQEERAMIFEPFFQGSHQRKGAvkGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIELP 454
Cdd:PRK09959 862 HAVIKMTIMDSGSGLSQEEQQQLFKRYSQTSAGRQQT--GSGLGLMICKELIKNMQGDLSLESHPGIGTTFTITIP 935
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
189-458 |
8.83e-18 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 85.04 E-value: 8.83e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 189 IERMINRLGEGRsLGNSVSFSGPSELRSVGQRILWLSERLSWLESQRHQFLRHLSHELKTPLASMREGTELLADqvvgPL 268
Cdd:PRK10604 167 LEAAAQRLGDGH-LAERIHFDEGSSLERLGVAFNQMADNINALIASKKQLIDGIAHELRTPLVRLRYRLEMSDN----LS 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 269 TPEQKEVVSILDSssrnLQKLIEQLLDY---NRKQADsaVELDNVELAPLVETVVSAHSLPARAKMMHTDVDLKATACLA 345
Cdd:PRK10604 242 AAESQALNRDIGQ----LEALIEELLTYarlDRPQNE--LHLSEPDLPAWLSTHLADIQAVTPEKTVRLDTPHQGDYGAL 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 346 EPMLLMSVLDNLYSNAVHYGAesGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFQGSHQRKGAVKGSGLGLSI 425
Cdd:PRK10604 316 DMRLMERVLDNLLNNALRYAH--SRVRVSLLLDGNQACLIVEDDGPGIPPEERERVFEPFVRLDPSRDRATGGCGLGLAI 393
|
250 260 270
....*....|....*....|....*....|....*.
gi 1447699692 426 ARDCIRRMQGELYlVDES---GQDVCFRIELPSSKN 458
Cdd:PRK10604 394 VHSIALAMGGSVN-CDESelgGARFSFSWPVWHNLP 428
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
225-454 |
1.84e-17 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 85.47 E-value: 1.84e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 225 SERLSWLESQRHQ----FLRHLSHELKTPLASMREGTELL-----ADQvvGPLTPEQKEVVSILDSSSRnlqkLIEQLLD 295
Cdd:PRK10490 650 SEEQARLASEREQlrnaLLAALSHDLRTPLTVLFGQAEILtldlaSEG--SPHARQASEIRQQVLNTTR----LVNNLLD 723
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 296 YNRKQADsAVELdNVELAPLVETVVSA-HSLPARAKMMHTDVDLKATACL--AEPMLLMSVLDNLYSNAVHYGAESGNIC 372
Cdd:PRK10490 724 MARIQSG-GFNL-RKEWLTLEEVVGSAlQMLEPGLSGHPINLSLPEPLTLihVDGPLFERVLINLLENAVKYAGAQAEIG 801
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 373 LRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFQGshQRKGAVKGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIE 452
Cdd:PRK10490 802 IDAHVEGERLQLDVWDNGPGIPPGQEQLIFDKFARG--NKESAIPGVGLGLAICRAIVEVHGGTIWAENRPEGGACFRVT 879
|
..
gi 1447699692 453 LP 454
Cdd:PRK10490 880 LP 881
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
353-454 |
3.88e-16 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 73.64 E-value: 3.88e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 353 VLDNLYSNAVHYGaeSGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFQGSHQRkgAVKGSGLGLSIARDCIRR 432
Cdd:cd16950 4 VLSNLVDNALRYG--GGWVEVSSDGEGNRTRIQVLDNGPGIAPEEVDELFQPFYRGDNAR--GTSGTGLGLAIVQRISDA 79
|
90 100
....*....|....*....|..
gi 1447699692 433 MQGELYLVDESGQDVCFRIELP 454
Cdd:cd16950 80 HGGSLTLANRAGGGLCARIELP 101
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
225-458 |
4.64e-16 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 80.40 E-value: 4.64e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 225 SERLSWLEsqrhQFLRHLSHELKTPLASMREGTELLADQVvgplTPEQKEVVSILDSSSRNLQKLIEQLLDYNRKQADSA 304
Cdd:COG5809 264 SEKLSVVG----ELAAGIAHEIRNPLTSLKGFIQLLKDTI----DEEQKTYLDIMLSELDRIESIISEFLVLAKPQAIKY 335
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 305 VELDnveLAPLVETVVSAhsLPARAkmMHTDVDLKATACLAEPMLLMS------VLDNLYSNAVHYGAESGNICLRSSLH 378
Cdd:COG5809 336 EPKD---LNTLIEEVIPL--LQPQA--LLKNVQIELELEDDIPDILGDenqlkqVFINLLKNAIEAMPEGGNITIETKAE 408
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 379 -GARVYIDVINTGTPIPQEERAMIFEPFFQGSHqrkgavKGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIELPSSK 457
Cdd:COG5809 409 dDDKVVISVTDEGCGIPEERLKKLGEPFYTTKE------KGTGLGLMVSYKIIEEHGGKITVESEVGKGTTFSITLPIKL 482
|
.
gi 1447699692 458 N 458
Cdd:COG5809 483 S 483
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
198-454 |
2.91e-15 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 77.20 E-value: 2.91e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 198 EGRSLGNSVSFSGPSELRSvgqrilwLSERLSWLESQRHQfLRHLSHELKTPLASMREGTELLADQvvgpltpeqkEVVS 277
Cdd:COG3290 160 DGRVVGAVATFRDRTELER-------LEEELEGVKELAEA-LRAQRHDFRNHLHTISGLLQLGEYD----------EALE 221
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 278 ILDSSSRNLQKLIEQLLDYnrkqadsaveLDNVELAPLVETVVSahslpaRAKMMHTDVDLKATACLAE----PMLLMSV 353
Cdd:COG3290 222 YIDEISEELQELIDSLLSR----------IGNPVLAALLLGKAA------RARERGIDLTIDIDSDLPDlplsDTDLVTI 285
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 354 LDNLYSNAVHY----GAESGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFF--QGSHqrkgavkGSGLGLSIAR 427
Cdd:COG3290 286 LGNLLDNAIEAveklPEEERRVELSIRDDGDELVIEVEDSGPGIPEELLEKIFERGFstKLGE-------GRGLGLALVK 358
|
250 260
....*....|....*....|....*..
gi 1447699692 428 DCIRRMQGELYLVDESGQDVCFRIELP 454
Cdd:COG3290 359 QIVEKYGGTIEVESEEGEGTVFTVRLP 385
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
350-454 |
1.00e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 69.66 E-value: 1.00e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 350 LMSVLDNLYSNAVHYGAESgnICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFQGSHQRKGAVKGSGLGLSIARDC 429
Cdd:cd16949 1 LARALENVLRNALRYSPSK--ILLDISQDGDQWTITITDDGPGVPEDQLEQIFLPFYRVDSARDRESGGTGLGLAIAERA 78
|
90 100
....*....|....*....|....*
gi 1447699692 430 IRRMQGELYLVDESGQDVCFRIELP 454
Cdd:cd16949 79 IEQHGGKIKASNRKPGGLRVRIWLP 103
|
|
| PRK10841 |
PRK10841 |
two-component system sensor histidine kinase RcsC; |
238-454 |
1.06e-14 |
|
two-component system sensor histidine kinase RcsC;
Pssm-ID: 182772 [Multi-domain] Cd Length: 924 Bit Score: 76.55 E-value: 1.06e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 238 FLRHLSHELKTPLASMREGTELLADQVvgpLTPEQKEVVSILDSSSRNLQKLIEQLLDYNR---KQadsaVELDNVELAP 314
Cdd:PRK10841 450 FLATVSHELRTPLYGIIGNLDLLQTKE---LPKGVDRLVTAMNNSSSLLLKIISDILDFSKiesEQ----LKIEPREFSP 522
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 315 L-VETVVSAHSLPARAK-------MMHTDVDLkatACLAEPMLLMSVLDNLYSNAVHYgAESGNICLRSSLHGARVYIDV 386
Cdd:PRK10841 523 ReVINHITANYLPLVVKkrlglycFIEPDVPV---ALNGDPMRLQQVISNLLSNAIKF-TDTGCIVLHVRVDGDYLSFRV 598
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1447699692 387 INTGTPIPQEERAMIFEPFFQGSHQRKGAVKGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIELP 454
Cdd:PRK10841 599 RDTGVGIPAKEVVRLFDPFFQVGTGVQRNFQGTGLGLAICEKLINMMDGDISVDSEPGMGSQFTIRIP 666
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
231-455 |
1.42e-14 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 75.43 E-value: 1.42e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 231 LESQRHQFLRHLSHELKTPLASMREGTELLADQV-VGPLtpeQKEVVSILDSSSRNLQKLIEQLLDYNRKQADSAVELDN 309
Cdd:PRK11006 200 LEGARRNFFANVSHELRTPLTVLQGYLEMMQDQPlEGAL---REKALHTMREQTQRMEGLVKQLLTLSKIEAAPTIDLNE 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 310 VELAPLVETVV--SAHSLPARAKMMHTDVDlKATACLAEPMLLMSVLDNLYSNAVHYGAESGNI--CLRSSLHGARvyID 385
Cdd:PRK11006 277 KVDVPMMLRVLerEAQTLSQGKHTITFEVD-NSLKVFGNEDQLRSAISNLVYNAVNHTPEGTHItvRWQRVPQGAE--FS 353
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 386 VINTGTPIPQEERAMIFEPFFQGSHQRKGAVKGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIELPS 455
Cdd:PRK11006 354 VEDNGPGIAPEHIPRLTERFYRVDKARSRQTGGSGLGLAIVKHALSHHDSRLEIESEVGKGTRFSFVLPE 423
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
224-454 |
2.08e-14 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 74.60 E-value: 2.08e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 224 LSERLSWLEsqrhQFLRHLSHELKTPL--ASMR-EGTELLADQVVGPLTPEQKEvvSILDSSSRNLQK---LIEQLLDYN 297
Cdd:PRK09303 144 LLEQLKFKD----RVLAMLAHDLRTPLtaASLAlETLELGQIDEDTELKPALIE--QLQDQARRQLEEierLITDLLEVG 217
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 298 R-KQADSAVELDNVELAPLVETVVS--AHSLPARAKMMHTDVDLKATACLAEPMLLMSVLDNLYSNAVHYGAESGNICLr 374
Cdd:PRK09303 218 RtRWEALRFNPQKLDLGSLCQEVILelEKRWLAKSLEIQTDIPSDLPSVYADQERIRQVLLNLLDNAIKYTPEGGTITL- 296
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 375 SSLH--GARVYIDVINTGTPIPQEERAMIFEPFFQgsHQRKGAVKGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIE 452
Cdd:PRK09303 297 SMLHrtTQKVQVSICDTGPGIPEEEQERIFEDRVR--LPRDEGTEGYGIGLSVCRRIVRVHYGQIWVDSEPGQGSCFHFT 374
|
..
gi 1447699692 453 LP 454
Cdd:PRK09303 375 LP 376
|
|
| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
135-460 |
4.47e-14 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 73.08 E-value: 4.47e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 135 VQATRTVVfSRGQQLQREIAErgqyfgwQSLVLFLVSLVMVLLFTRMIIGPVKNIERMINRLG---EGRSLGN---SVSF 208
Cdd:PRK10755 39 VQATLSAR-NNDEHVMKEIRE-------AVASLLVPSLVMVSLTLLICFQAVRWITRPLAELQkelEARTADNltpIAIH 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 209 SGPSELRSVGQRILWLSERLSWLESQRHQFLRHLSHELKTPLASMREGTELLADQVVgpltPEQKEVVSILDSssrnLQK 288
Cdd:PRK10755 111 SSTLEIEAVTSALNQLVSRLTSTLDQERLFTADVAHELRTPLAGIRLHLELLEKQHH----IDVAPLIARLDQ----MMH 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 289 LIEQLLDYNR-KQADSAVELDNVElapLVETVVsahsLPARAKM--MHT----DVDLKATACLA----EPMLLMSVLDNL 357
Cdd:PRK10755 183 TVEQLLQLARaGQSFSSGHYQTVK---LLEDVI----LPSQDELseMLEqrqqTLLLPESAADItvqgDATLLRLLLRNL 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 358 YSNAVHYGAESGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFQgSHQRKGavkGSGLGLSIARDCIRRMQGEL 437
Cdd:PRK10755 256 VENAHRYSPEGSTITIKLSQEDGGAVLAVEDEGPGIDESKCGELSKAFVR-MDSRYG---GIGLGLSIVSRITQLHHGQF 331
|
330 340
....*....|....*....|....*.
gi 1447699692 438 YL---VDESGQDVCfrIELPSSKNTK 460
Cdd:PRK10755 332 FLqnrQERSGTRAW--VWLPKAQNVA 355
|
|
| PRK11091 |
PRK11091 |
aerobic respiration control sensor protein ArcB; Provisional |
238-454 |
4.95e-14 |
|
aerobic respiration control sensor protein ArcB; Provisional
Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 74.59 E-value: 4.95e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 238 FLRHLSHELKTPLASMREGTELLADQvvgPLTPEQKEVVSILDSSSRNLQKLIEQLLDYNrKQADSAVELDN--VELAPL 315
Cdd:PRK11091 286 FISTISHELRTPLNGIVGLSRILLDT---ELTAEQRKYLKTIHVSAITLGNIFNDIIDMD-KMERRKLQLDNqpIDFTDF 361
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 316 VETVVSAHSLPARAK----MMHTDVDLKATAClAEPMLLMSVLDNLYSNAVHYGAEsGNICLRSSLH-GARVYIDVINTG 390
Cdd:PRK11091 362 LADLENLSGLQAEQKglrfDLEPLLPLPHKVI-TDGTRLRQILWNLISNAVKFTQQ-GGVTVRVRYEeGDMLTFEVEDSG 439
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1447699692 391 TPIPQEERAMIFEPFFQ--GSHQRKGAVkGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIELP 454
Cdd:PRK11091 440 IGIPEDELDKIFAMYYQvkDSHGGKPAT-GTGIGLAVSKRLAQAMGGDITVTSEEGKGSCFTLTIH 504
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
353-454 |
7.28e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 67.41 E-value: 7.28e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 353 VLDNLYSNAVHYGAESGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFQGSHQRKGAvkGSGLGLSIARDCIRR 432
Cdd:cd16923 4 VFSNLLSNAIKYSPENTRIYITSFLTDDVVNIMFKNPSSHPLDFKLEKLFERFYRGDNSRNTE--GAGLGLSIAKAIIEL 81
|
90 100
....*....|....*....|..
gi 1447699692 433 MQGELYLVDESGQDVcFRIELP 454
Cdd:cd16923 82 HGGSASAEYDDNHDL-FKVRLP 102
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
234-301 |
8.35e-14 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 66.08 E-value: 8.35e-14
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1447699692 234 QRHQFLRHLSHELKTPLASMREGTELLADqvvGPLTPEQKEVVSILDSSSRNLQKLIEQLLDYNRKQA 301
Cdd:pfam00512 1 AKSEFLANLSHELRTPLTAIRGYLELLRD---EKLDEEQREYLETILRSAERLLRLINDLLDLSRIEA 65
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
234-301 |
1.31e-13 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 65.28 E-value: 1.31e-13
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1447699692 234 QRHQFLRHLSHELKTPLASMREGTELLADqvvGPLTPEQKEVVSILDSSSRNLQKLIEQLLDYNRKQA 301
Cdd:smart00388 1 AKREFLANLSHELRTPLTAIRGYLELLLD---TELSEEQREYLETILREAERLLRLINDLLDLSRIEA 65
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
243-454 |
1.50e-13 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 72.51 E-value: 1.50e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 243 SHELKTPLASMREGTELLADQVvgPLTPEQKEVVSILDSSSRNLQKLIEQLLDYNRKqadSAVELDNVELAPLVETVVSA 322
Cdd:PRK10364 245 AHEIRNPLSSIKGLAKYFAERA--PAGGEAHQLAQVMAKEADRLNRVVSELLELVKP---THLALQAVDLNDLINHSLQL 319
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 323 HSLPARAKMMhtDVDLKATACL----AEPMLLMSVLDNLYSNAVHYGAESGNICLRSSLHGARVYIDVINTGTPIPQEER 398
Cdd:PRK10364 320 VSQDANSREI--QLRFTANDTLpeiqADPDRLTQVLLNLYLNAIQAIGQHGVISVTASESGAGVKISVTDSGKGIAADQL 397
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1447699692 399 AMIFEPFFQGSHQrkgavkGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIELP 454
Cdd:PRK10364 398 EAIFTPYFTTKAE------GTGLGLAVVHNIVEQHGGTIQVASQEGKGATFTLWLP 447
|
|
| HATPase_YcbM-like |
cd16947 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
333-453 |
2.96e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).
Pssm-ID: 340423 [Multi-domain] Cd Length: 125 Bit Score: 66.38 E-value: 2.96e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 333 HTDVDLKATACLAEPMLLMSVLDNLYSNAVHYGAESGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFQGSHQR 412
Cdd:cd16947 4 EINIPDRPIYANANTEALQRILKNLISNAIKYGSDGKFLGMTLREDEKHVYIDIWDKGKGISETEKDHVFERLYTLEDSR 83
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 1447699692 413 KGAVKGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIEL 453
Cdd:cd16947 84 NSAKQGNGLGLTITKRLAESMGGSIYVNSKPYEKTVFTVTL 124
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
353-454 |
3.49e-13 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 65.59 E-value: 3.49e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 353 VLDNLYSNAVHYGAESGNI-CLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFQGSHQRKGAVKGSGLGLSIARDCIR 431
Cdd:cd16925 8 VVLNLLSNAFKFTPDGGRIrCILEKFRLNRFLLTVSDSGPGIPPNLREEIFERFRQGDGSSTRAHGGTGLGLSIVKEFVE 87
|
90 100
....*....|....*....|...
gi 1447699692 432 RMQGELYLVDESGQDVCFRIELP 454
Cdd:cd16925 88 LHGGTVTVSDAPGGGALFQVELP 110
|
|
| glnL |
PRK11073 |
nitrogen regulation protein NR(II); |
213-454 |
1.22e-12 |
|
nitrogen regulation protein NR(II);
Pssm-ID: 182947 [Multi-domain] Cd Length: 348 Bit Score: 68.95 E-value: 1.22e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 213 ELRSVGQRilwlsERLSWLESQRHQ------FLRHLSHELKTPLASMREGTELLADQVVGPLTPEQKEVvsILDSSSRnL 286
Cdd:PRK11073 107 EMAPMDNQ-----RRLSQEQLQHAQqvaardLVRGLAHEIKNPLGGLRGAAQLLSKALPDPALTEYTKV--IIEQADR-L 178
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 287 QKLIEQLLDYNR---KQADSaveldnveLAPLVETVVSAHSLPARAKM-MHTDVDLKATACLAEPMLLMSVLDNLYSNAV 362
Cdd:PRK11073 179 RNLVDRLLGPQRpgtHVTES--------IHKVAERVVQLVSLELPDNVrLIRDYDPSLPELAHDPDQIEQVLLNIVRNAL 250
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 363 H-YGAESGNICLRS------SLHGAR----VYIDVINTGTPIPQEERAMIFEPFFQGshqRKGavkGSGLGLSIARDCIR 431
Cdd:PRK11073 251 QaLGPEGGTITLRTrtafqlTLHGERyrlaARIDIEDNGPGIPPHLQDTLFYPMVSG---REG---GTGLGLSIARNLID 324
|
250 260
....*....|....*....|...
gi 1447699692 432 RMQGELYLVDESGQDVcFRIELP 454
Cdd:PRK11073 325 QHSGKIEFTSWPGHTE-FSVYLP 346
|
|
| PRK11107 |
PRK11107 |
hybrid sensory histidine kinase BarA; Provisional |
238-454 |
1.60e-12 |
|
hybrid sensory histidine kinase BarA; Provisional
Pssm-ID: 236848 [Multi-domain] Cd Length: 919 Bit Score: 69.88 E-value: 1.60e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 238 FLRHLSHELKTPLasmregtellaDQVVG--------PLTPEQKEVVSILDSSSRNLQKLIEQLLDYNRKQADsAVELDN 309
Cdd:PRK11107 296 FLANMSHELRTPL-----------NGVIGftrqtlktPLTPTQRDYLQTIERSANNLLAIINDILDFSKLEAG-KLVLEN 363
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 310 V--ELAPLVETVVS--AHSlpARAKMMHTDVDLKAT---ACLAEPMLLMSVLDNLYSNAVHYgAESGNICLRSSLHGAR- 381
Cdd:PRK11107 364 IpfSLRETLDEVVTllAHS--AHEKGLELTLNIDPDvpdNVIGDPLRLQQIITNLVGNAIKF-TESGNIDILVELRALSn 440
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 382 ----VYIDVINTGTPIPQEERAMIFEPFFQG--SHQRK-GavkGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIELP 454
Cdd:PRK11107 441 tkvqLEVQIRDTGIGISERQQSQLFQAFRQAdaSISRRhG---GTGLGLVITQKLVNEMGGDISFHSQPNRGSTFWFHLP 517
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
232-298 |
5.18e-12 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 60.69 E-value: 5.18e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1447699692 232 ESQRHQFLRHLSHELKTPLASMREGTELLADQVVGPltPEQKEVVSILDSSSRNLQKLIEQLLDYNR 298
Cdd:cd00082 1 LQAKGEFLANVSHELRTPLTAIRGALELLEEELLDD--EEQREYLERIREEAERLLRLINDLLDLSR 65
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
164-427 |
2.26e-11 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 65.44 E-value: 2.26e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 164 SLVLFLVSL-VMVLLFTRMIIGPVKNIERMINRLgEGRSLGNSVSFSG---PSELRSVGQRILWLSERLSWLESQRHQFL 239
Cdd:PRK10337 163 QLIPWLVALpIMLIILMVLLGRELAPLKKLALAL-RMRDPDSETPLNAtgvPSEVRPLVEALNQLFARTHAMMVRERRFT 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 240 RHLSHELKTPLASMREGTELLadQVVGPLTPEQKEVVSILDSSSRNLQKLIEQLLDYNRkqADSAVELDNVE---LAPLV 316
Cdd:PRK10337 242 SDAAHELRSPLAALKVQTEVA--QLSDDDPQARKKALLQLHAGIDRATRLVDQLLTLSR--LDSLDNLQDVAeipLEDLL 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 317 ETVVSAHSLPARAKMMHTDVDLKATACL--AEPMLLMSVLDNLYSNAVHYGAESGNICLRSSLHGARvyidVINTGTPIP 394
Cdd:PRK10337 318 QSAVMDIYHTAQQAGIDVRLTLNAHPVIrtGQPLLLSLLVRNLLDNAIRYSPQGSVVDVTLNARNFT----VRDNGPGVT 393
|
250 260 270
....*....|....*....|....*....|...
gi 1447699692 395 QEERAMIFEPFFQGSHQRKgavKGSGLGLSIAR 427
Cdd:PRK10337 394 PEALARIGERFYRPPGQEA---TGSGLGLSIVR 423
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
238-437 |
3.47e-11 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 65.18 E-value: 3.47e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 238 FLRHLSHELKTPLASMREGTELLADQvvgplTPEQKEVVSILDSSSRNLQKLIEQLLDY-NRKQADS-AVELDNVELAPL 315
Cdd:PRK09835 265 FSADIAHEIRTPITNLITQTEIALSQ-----SRSQKELEDVLYSNLEELTRMAKMVSDMlFLAQADNnQLIPEKKMLDLA 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 316 VETVVSAHSLPARAKMMHTDVDLKATACLAE--PMLLMSVLDNLYSNAVHYGAESGNICLRSSLHGARVYIDVINTGTPI 393
Cdd:PRK09835 340 DEVGKVFDFFEAWAEERGVELRFVGDPCQVAgdPLMLRRAISNLLSNALRYTPAGEAITVRCQEVDHQVQLVVENPGTPI 419
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1447699692 394 PQEERAMIFEPFFQ--GSHQRKGavKGSGLGLSIARDCIRRMQGEL 437
Cdd:PRK09835 420 APEHLPRLFDRFYRvdPSRQRKG--EGSGIGLAIVKSIVVAHKGTV 463
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
139-453 |
4.72e-11 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 64.65 E-value: 4.72e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 139 RTVVFSRGQQLQREIAERGQYFGWQSLVLFLVSLVMVLLFTRMIIGPVKNIERMINRLGEGRSLgnSVSFSGPSELRSVG 218
Cdd:COG2972 138 TLVSLIPKSELFRGLFSLRRLILLIILLLLLLALLLSYLLSRSITRPIKRLKKAMKKVEKGDLV--RLEVSGNDEIGILA 215
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 219 QRILWLSERLSWLESQRHQFLRHLSH-ELKT------P------LASMREgtelLAdqvvgpLTPEQKEVVSILDSssrn 285
Cdd:COG2972 216 RSFNEMVERIKELIEEVYELELEKKEaELKAlqaqinPhflfntLNSIRW----LA------ELEDPEEAEEMLEA---- 281
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 286 lqkLIEqLLDYNRKQADSAVELDNvELApLVETVVSAHSLPARAKM-MHTDVDLKATACLAEPMLLMSVLDNlysnAVHY 364
Cdd:COG2972 282 ---LSK-LLRYSLSKGDELVTLEE-ELE-LIKSYLEIQKLRFGDRLeVEIEIDEELLDLLIPKLILQPLVEN----AIEH 351
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 365 GAES----GNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFQGSHqrkgavkGSGLGLSIARDCIRRMQGELYLV 440
Cdd:COG2972 352 GIEPkeggGTIRISIRKEGDRLVITVEDNGVGMPEEKLEKLLEELSSKGE-------GRGIGLRNVRERLKLYYGEEYGL 424
|
330
....*....|....
gi 1447699692 441 D-ESGQDVCFRIEL 453
Cdd:COG2972 425 EiESEPGEGTTVTI 438
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
350-453 |
7.34e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 58.62 E-value: 7.34e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 350 LMSVLDNLYSNA---VHyGAESGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFQgshqRKGAVKGSGLGLSIA 426
Cdd:cd16976 1 IQQVLMNLLQNAldaMG-KVENPRIRIAARRLGGRLVLVVRDNGPGIAEEHLSRVFDPFFT----TKPVGKGTGLGLSIS 75
|
90 100
....*....|....*....|....*..
gi 1447699692 427 RDCIRRMQGELYLVDESGQDVCFRIEL 453
Cdd:cd16976 76 YGIVEEHGGRLSVANEEGAGARFTFDL 102
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
242-456 |
7.54e-11 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 64.31 E-value: 7.54e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 242 LSHELKTPLASMREGTELlADQVVGPLTPEQKEVVSILDSSSRnLQKLIEQLLDYNRKQaDSAVEldNVELAPLVETVVS 321
Cdd:PRK13837 457 IAHNFNNILGAILGYAEM-ALNKLARHSRAARYIDEIISAGAR-ARLIIDQILAFGRKG-ERNTK--PFDLSELVTEIAP 531
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 322 --AHSLPARAKMmhtDVDLKA--TACLAEPMLLMSVLDNLYSNAVHYGAESGNICLRSSLH---------------GARV 382
Cdd:PRK13837 532 llRVSLPPGVEL---DFDQDQepAVVEGNPAELQQVLMNLCSNAAQAMDGAGRVDISLSRAklrapkvlshgvlppGRYV 608
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1447699692 383 YIDVINTGTPIPQEERAMIFEPFFQgshQRKGavkGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIELPSS 456
Cdd:PRK13837 609 LLRVSDTGAGIDEAVLPHIFEPFFT---TRAG---GTGLGLATVHGIVSAHAGYIDVQSTVGRGTRFDVYLPPS 676
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
346-439 |
1.58e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 57.86 E-value: 1.58e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 346 EPMLLMSVLDNLYSNAVHYGAESGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFQGSHQRKGAvKGSGLGLSI 425
Cdd:cd16945 1 DPFLLRQAINNLLDNAIDFSPEGGLIALQLEADTEGIELLVFDEGSGIPDYALNRVFERFYSLPRPHSGQ-KSTGLGLAF 79
|
90
....*....|....
gi 1447699692 426 ARDCIRRMQGELYL 439
Cdd:cd16945 80 VQEVAQLHGGRITL 93
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
353-454 |
2.84e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 57.30 E-value: 2.84e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 353 VLDNLYSNAVHYGAESGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFQGSHQRKgAVKGSGLGLSIARDCIRR 432
Cdd:cd16948 9 IIGQIVSNALKYSKQGGKIEIYSETNEQGVVLSIKDFGIGIPEEDLPRVFDKGFTGENGRN-FQESTGMGLYLVKKLCDK 87
|
90 100
....*....|....*....|..
gi 1447699692 433 MQGELYLVDESGQDVCFRIELP 454
Cdd:cd16948 88 LGHKIDVESEVGEGTTFTITFP 109
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
350-457 |
3.45e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 57.21 E-value: 3.45e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 350 LMSVLDNLYSNAVHYGAESGNICLRSSL--HGARvyIDVINTGTPIPQEERAMIFEPFFQGSHQRKGAVKGSGLGLSIAR 427
Cdd:cd16952 1 LRSAFSNLVSNAVKYTPPSDTITVRWSQeeSGAR--LSVEDTGPGIPPEHIPRLTERFYRVDIERCRNTGGTGLGLAIVK 78
|
90 100 110
....*....|....*....|....*....|
gi 1447699692 428 DCIRRMQGELYLVDESGQDVCFRIELPSSK 457
Cdd:cd16952 79 HVMSRHDARLLIASELGKGSRFTCLFPSSR 108
|
|
| PRK10815 |
PRK10815 |
two-component system sensor histidine kinase PhoQ; |
129-437 |
4.35e-10 |
|
two-component system sensor histidine kinase PhoQ;
Pssm-ID: 182754 [Multi-domain] Cd Length: 485 Bit Score: 61.57 E-value: 4.35e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 129 SANTEMVQATRTVVFSRGQQLQREIaergQYFGWQSLVLfLVSLVMVL----LFTRMIIGPVKNIERMINRLGEGRSlgN 204
Cdd:PRK10815 163 PATSRLPKLTIVVVDTIPQELQRSY----MVWSWFSYVL-LANLLLVIpllwLAAWWSLRPIEALAKQVRELEEGER--E 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 205 SVSFSGPSELRSVGQR--ILWLSERlswlesQRHQFLR----HLSHELKTPLA-------SMREGTELladqvvgplTPE 271
Cdd:PRK10815 236 QLDPNPPRELTSLVRNlnRLLKNER------ERYTKYRttltDLTHSLKTPLAvlqstlrSLRSGKQM---------SVE 300
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 272 QKEVVsILDSSSRnlqklIEQLLDY--NRK--QADSAV---ELDNVelAPLVETVVSAHSLPARAKMMHTDVDLKA-TAC 343
Cdd:PRK10815 301 QAEPI-MLEQISR-----ISQQIGYylHRAsmRSEHNLlsrELHSV--APLLDNLTSALNKVYQRKGVNITLDISPeITF 372
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 344 LAEPMLLMSVLDNLYSNAVHYGAESGNICLRSSLHGARVYIDviNTGTPIPQEERAMIFEpffQGshQRKGAVK-GSGLG 422
Cdd:PRK10815 373 VGEKNDFMEVMGNVLDNACKYCLEFVEISARQTDEHLHIVVE--DDGPGIPESKRELIFD---RG--QRADTLRpGQGLG 445
|
330
....*....|....*
gi 1447699692 423 LSIARDCIRRMQGEL 437
Cdd:PRK10815 446 LSVAREITEQYEGKI 460
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
353-454 |
4.95e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 56.67 E-value: 4.95e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 353 VLDNLYSNAVHYGAESGNICLRssLHGARVYIDVINTGTPIPQEERAMIFEPFFQGSHQRKGAVKGSGLGLSIARDCIRR 432
Cdd:cd16939 4 ALDNLLRNALRYAHRTVRIALL--VSGGRLTLIVEDDGPGIPAAARERVFEPFVRLDPSRDRATGGFGLGLAIVHRVALW 81
|
90 100
....*....|....*....|..
gi 1447699692 433 MQGELYLVDESGQDVCFRIELP 454
Cdd:cd16939 82 HGGHVECDDSELGGACFRLTWP 103
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
350-437 |
1.08e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 55.55 E-value: 1.08e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 350 LMSVLDNLYSNAVHYGAESGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFQGSHQRKGAVKGSGLGLSIARDC 429
Cdd:cd16946 5 LQQLFVNLLENSLRYTDTGGKLRIRAAQTPQEVRLDVEDSAPGVSDDQLARLFERFYRVESSRNRASGGSGLGLAICHNI 84
|
....*...
gi 1447699692 430 IRRMQGEL 437
Cdd:cd16946 85 ALAHGGTI 92
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
353-454 |
1.65e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 55.10 E-value: 1.65e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 353 VLDNLYSNAV----HYGAESGNICLRSSLHGAR-VYIDVINTGTPIPQEERAMIFEPFFQGShqrkgaVKGSGLGLSIAR 427
Cdd:cd16920 4 VLINLVRNGIeamsEGGCERRELTIRTSPADDRaVTISVKDTGPGIAEEVAGQLFDPFYTTK------SEGLGMGLSICR 77
|
90 100
....*....|....*....|....*..
gi 1447699692 428 DCIRRMQGELYLVDESGQDVCFRIELP 454
Cdd:cd16920 78 SIIEAHGGRLSVESPAGGGATFQFTLP 104
|
|
| HATPase_Glnl-NtrB-like |
cd16918 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
350-454 |
1.94e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli GlnL (synonyms NtrB and NRII); This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs), similar to Escherichia coli GlnL/NtrB/NRII HK of the two-component regulatory system (TCS) GlnL/GlnG (NtrB-NtrC, or NRII-NRI), which regulates the transcription of genes encoding metabolic enzymes and permeases in response to carbon and nitrogen status in E. coli and related bacteria. Also included in this family are Rhodobacter capsulatus NtrB, Azospirillum brasilense NtrB, Vibrio alginolyticus NtrB, Rhizobium leguminosarum biovar phaseoli NtrB, and Herbaspirillum seropedicae NtrB. Escherichia coli GlnL/NtrB/NRII is both a kinase and a phosphatase, catalyzing the phosphorylation and dephosphorylation of GlnG/NtrC/NRI. The kinase and phosphatase activities of GlnL/NtrB/NRII are regulated by the PII signal transduction protein, which on binding to GlnL/NtrB/NRII, inhibits the kinase activity of GlnL/NtrB/NRII and activates the GlnL/NtrB/NRII phosphatase activity. Proteins having this HATPase domain also have a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also contain PAS sensor domain(s).
Pssm-ID: 340395 [Multi-domain] Cd Length: 109 Bit Score: 55.10 E-value: 1.94e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 350 LMSVLDNLYSNAVHYGAES-GNICLRSS------LHGAR----VYIDVINTGTPIPQEERAMIFEPFFQGSHQrkgavkG 418
Cdd:cd16918 1 LIQVFLNLVRNAAQALAGSgGEIILRTRtqrqvtLGHPRhrlaLRVSVIDNGPGIPPDLQDTIFYPMVSGREN------G 74
|
90 100 110
....*....|....*....|....*....|....*.
gi 1447699692 419 SGLGLSIARDCIRRMQGELYLVDESGQDVcFRIELP 454
Cdd:cd16918 75 TGLGLAIAQNIVSQHGGVIECDSQPGHTV-FSVSLP 109
|
|
| HATPase_CckA-like |
cd16919 |
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar ... |
379-454 |
1.96e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar to Brucella abortus 2308 CckA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) similar to Brucella abortus 2308 CckA, which is a component of an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival; phosphoryl transfer initiates from the sensor kinase CckA and proceeds via the ChpT phosphotransferase to two regulatory substrates: the DNA-binding response regulator CtrA and the phospho-receiver protein CpdR. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), a REC signal receiver domain, and some contain PAS or PAS and GAF sensor domain(s).
Pssm-ID: 340396 [Multi-domain] Cd Length: 116 Bit Score: 55.08 E-value: 1.96e-09
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1447699692 379 GARVYIDVINTGTPIPQEERAMIFEPFFQgshqRKGAVKGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIELP 454
Cdd:cd16919 45 GNYVCLEVSDTGSGMPAEVLRRAFEPFFT----TKEVGKGTGLGLSMVYGFVKQSGGHLRIYSEPGVGTTVRIYLP 116
|
|
| ArsS_fam_HK |
NF038389 |
ArsS family sensor histidine kinase; ArsS in Helicobacter pylori is a sensor histidine kinase ... |
165-426 |
1.37e-08 |
|
ArsS family sensor histidine kinase; ArsS in Helicobacter pylori is a sensor histidine kinase participating in a two-component system that controls the response to acid conditiions encountered during the process of gastric colonization. This HMM identified ArsS itself but also a broader collection of apparent orthologs from closely related non-gastric colonizers such as Helicobacter hepaticus, Campylobacter jejuni and Wolinella succinogenes. See BlastRule NBR014349 for specific identification of ArsS itself, distinguished by a signature His residue that becomes protonated at low pH.
Pssm-ID: 468500 [Multi-domain] Cd Length: 402 Bit Score: 56.78 E-value: 1.37e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 165 LVLFLVS-LVMVLLFTRMI--IGPVKNIERMINRLGEGRSLGNSVSFSGP------SELRSVGQRILWLserlswLESqR 235
Cdd:NF038389 134 IVFFIFLiLLLLILYISVLksLKPLKKLKKQIKKFANGDFDFIKSESNGDeigevaNEFDKAVKKIKAL------NES-R 206
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 236 HQFLRHLSHELKTPLASMREGTELLADqvvgpltPEQKEV-VSI---LDS-----------SSRN---------LQKLIE 291
Cdd:NF038389 207 QLFLRNIMHELKTPITKGRIVAEMLED-------EKQKERlISIferLESlinefakieqlTSKNyklnkkeyrLSDIID 279
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 292 QLLDY---NRKQADSAVELDNVelaplvetvvsahslparakMMHTDVDLKATAclaepmllmsvLDNLYSNAVHYgaes 368
Cdd:NF038389 280 EAIDMlmiDDSSVIIKVSLEDF--------------------KLNVDFELFSLA-----------IKNLIDNAIKY---- 324
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1447699692 369 gniclrSSLHGARVYID-----VINTGTPIPqEERAMIFEPFFQGSHQRKgavKGSGLGLSIA 426
Cdd:NF038389 325 ------SPDKKVTIEIKgdkieFKNKGEPLE-EPLEYYFEPFFKGNEKSK---SGFGLGLYIV 377
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
350-454 |
3.93e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 51.42 E-value: 3.93e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 350 LMSVLDNLYSNAVHYGA-ESGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFqgSHQRKGAVKG--SGLGLSIA 426
Cdd:cd16953 1 LGQVLRNLIGNAISFSPpDTGRITVSAMPTGKMVTISVEDEGPGIPQEKLESIFDRFY--TERPANEAFGqhSGLGLSIS 78
|
90 100 110
....*....|....*....|....*....|....
gi 1447699692 427 RDCIRRMQGElyLVDESGQD------VCFRIELP 454
Cdd:cd16953 79 RQIIEAHGGI--SVAENHNQpgqvigARFTVQLP 110
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
349-452 |
4.31e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 50.92 E-value: 4.31e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 349 LLMSVLDNLYSNAVHYGAESGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFQGSHQRKGAvKGSGLGLSIARD 428
Cdd:cd16975 4 LLSRALINIISNACQYAPEGGTVSISIYDEEEYLYFEIWDNGHGFSEQDLKKALELFYRDDTSRRSG-GHYGMGLYIAKN 82
|
90 100
....*....|....*....|....
gi 1447699692 429 CIRRMQGELYLVDESGQDVCFRIE 452
Cdd:cd16975 83 LVEKHGGSLIIENSQKGGAEVTVK 106
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
353-454 |
1.75e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 49.46 E-value: 1.75e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 353 VLDNLYSNAVHY--GAESGNICLR---SSLHGARVYIDVINTGTPIPQEERAMIFEPFFQGSHqrkgavKGSGLGLSIAR 427
Cdd:cd16944 8 VLTNILKNAAEAieGRPSDVGEVRirvEADQDGRIVLIVCDNGKGFPREMRHRATEPYVTTRP------KGTGLGLAIVK 81
|
90 100
....*....|....*....|....*..
gi 1447699692 428 DCIRRMQGELYLVDESGQDVCFRIELP 454
Cdd:cd16944 82 KIMEEHGGRISLSNREAGGACIRIILP 108
|
|
| HATPase_PhoQ-like |
cd16954 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
350-453 |
2.13e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.
Pssm-ID: 340430 [Multi-domain] Cd Length: 135 Bit Score: 49.94 E-value: 2.13e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 350 LMSVLDNLYSNAVHYGAESGNICLRSSLHGARVYIDviNTGTPIPQEERAMIFEPFFQGSHQRKGavkgSGLGLSIARDC 429
Cdd:cd16954 38 LMELLGNLLDNACKWCLEFVEVTARQTDGGLHLIVD--DDGPGVPESQRSKIFQRGQRLDEQRPG----QGLGLAIAKEI 111
|
90 100
....*....|....*....|....
gi 1447699692 430 IRRMQGELYLVDESGQDVCFRIEL 453
Cdd:cd16954 112 VEQYGGELSLSDSPLGGARFEVVF 135
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
353-456 |
2.14e-06 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 50.12 E-value: 2.14e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 353 VLDNLYSNAVHYGAESGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFQGSHqrkgavKGSGLGLSIARDCIRR 432
Cdd:COG5805 399 VFINLIKNAIEAMPNGGTITIHTEEEDNSVIIRVIDEGIGIPEERLKKLGEPFFTTKE------KGTGLGLMVSYKIIEN 472
|
90 100
....*....|....*....|....
gi 1447699692 433 MQGELYLVDESGQDVCFRIELPSS 456
Cdd:COG5805 473 HNGTIDIDSKVGKGTTFTITLPLS 496
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
346-425 |
3.55e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 45.86 E-value: 3.55e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 346 EPMLLMSVLDNLYSNAVHYGAESGNICLRSSLHGARVYIdVINTGTPIPQEERAMIFEPFFQGSHQrkgAVKGSGLGLSI 425
Cdd:cd16940 10 DALLLFLLLRNLVDNAVRYSPQGSRVEIKLSADDGAVIR-VEDNGPGIDEEELEALFERFYRSDGQ---NYGGSGLGLSI 85
|
|
| PRK13557 |
PRK13557 |
histidine kinase; Provisional |
288-456 |
1.15e-05 |
|
histidine kinase; Provisional
Pssm-ID: 237425 [Multi-domain] Cd Length: 540 Bit Score: 47.74 E-value: 1.15e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 288 KLIEQLLDYNRKQadsavELDN--VELAPLVETVVS--AHSLpARAKMMHTDVDLKATACLAEPMLLMSVLDNLYSNAVH 363
Cdd:PRK13557 218 TLTQQLLAFARKQ-----RLEGrvLNLNGLVSGMGElaERTL-GDAVTIETDLAPDLWNCRIDPTQAEVALLNVLINARD 291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 364 YGAESGNICLRSS---------------LHGARVYIDVINTGTPIPQEERAMIFEPFFqgshQRKGAVKGSGLGLSIARD 428
Cdd:PRK13557 292 AMPEGGRVTIRTRnveiededlamyhglPPGRYVSIAVTDTGSGMPPEILARVMDPFF----TTKEEGKGTGLGLSMVYG 367
|
170 180
....*....|....*....|....*...
gi 1447699692 429 CIRRMQGELYLVDESGQDVCFRIELPSS 456
Cdd:PRK13557 368 FAKQSGGAVRIYSEVGEGTTVRLYFPAS 395
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
350-454 |
2.40e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 43.08 E-value: 2.40e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 350 LMSVLDNLYSNAVHYG--AESGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEpFFQGSHQRkGAVKGSGLGLSIAR 427
Cdd:cd16921 1 LGQVLTNLLGNAIKFRrpRRPPRIEVGAEDVGEEWTFYVRDNGIGIDPEYAEKVFG-IFQRLHSR-EEYEGTGVGLAIVR 78
|
90 100
....*....|....*....|....*..
gi 1447699692 428 DCIRRMQGELYLVDESGQDVCFRIELP 454
Cdd:cd16921 79 KIIERHGGRIWLESEPGEGTTFYFTLP 105
|
|
| nifL_nitrog |
TIGR02938 |
nitrogen fixation negative regulator NifL; NifL is a modulator of the nitrogen fixation ... |
348-448 |
1.21e-04 |
|
nitrogen fixation negative regulator NifL; NifL is a modulator of the nitrogen fixation positive regulator protein NifA, and is therefore a negative regulator. It binds NifA. NifA and NifL are encoded by adjacent genes. [Central intermediary metabolism, Nitrogen fixation, Regulatory functions, Protein interactions]
Pssm-ID: 131984 [Multi-domain] Cd Length: 494 Bit Score: 44.51 E-value: 1.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 348 MLLMSVLDNLYSNAVHYGAESGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFF--QGSHQrkgavKGSGLGLSI 425
Cdd:TIGR02938 390 SLFKALVDNAIEAMNIKGWKRRELSITTALNGDLIVVSILDSGPGIPQDLRYKVFEPFFttKGGSR-----KHIGMGLSV 464
|
90 100
....*....|....*....|...
gi 1447699692 426 ARDCIRRMQGeLYLVDESGQDVC 448
Cdd:TIGR02938 465 AQEIVADHGG-IIDLDDDYSEGC 486
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
288-439 |
2.25e-04 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 43.52 E-value: 2.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 288 KLIEQLLDYNRKQADSAVELDnvelapLVETVVSAHSLPA-RAKM----MHTDVDLKAtacLAEPMLLMSVLDNLYSNAV 362
Cdd:COG4192 486 KIIKSLRQFSRKSDTPLQPVD------LRQVIEQAWELVEsRAKPqqitLHIPDDLMV---QGDQVLLEQVLVNLLVNAL 556
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1447699692 363 HYGAESGNICLRSSLHGARVYIDVINTGTPIPQEERamIFEPFFQGSHQrkgavkGSGLGLSIARDCIRRMQGELYL 439
Cdd:COG4192 557 DAVATQPQISVDLLSNAENLRVAISDNGNGWPLVDK--LFTPFTTTKEV------GLGLGLSICRSIMQQFGGDLYL 625
|
|
| PRK10618 |
PRK10618 |
phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional |
235-454 |
4.42e-04 |
|
phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional
Pssm-ID: 236726 [Multi-domain] Cd Length: 894 Bit Score: 43.00 E-value: 4.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 235 RHQFLRHLSHELKTPLASMREgtelLADQVVGPLTPE-QKEVVSILDSSSRNLQKLIE--QLLdyNRKQADS-AVELDNV 310
Cdd:PRK10618 450 RKAFLQNIGDELKQPLQSLAQ----LAAQLRQTSDEEqQQPELDQLAEQSDVLVRLVDniQLL--NMLETQDwKPEQELF 523
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 311 ELAPLVETVVSAhSLPA-RAK--MMHTDVDLKATAC-LAEPMLLMSVLDNLYSNAV---HYGAESGNICLRSSlHGARVY 383
Cdd:PRK10618 524 SLQDLIDEVLPE-VLPAiKRKglQLLIHNHLKAEQLrIGDRDALRKILLLLLNYAItttAYGKITLEVDQDES-SPDRLT 601
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1447699692 384 IDVINTGTPIPQEERAMIFEPFFQGSHQRKGAvKGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIELP 454
Cdd:PRK10618 602 IRILDTGAGVSIKELDNLHFPFLNQTQGDRYG-KASGLTFFLCNQLCRKLGGHLTIKSREGLGTRYSIHLK 671
|
|
| PRK13559 |
PRK13559 |
hypothetical protein; Provisional |
231-398 |
5.21e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 237427 [Multi-domain] Cd Length: 361 Bit Score: 42.11 E-value: 5.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 231 LESQRHQFLRHLSHELKTPLAsmregtelLADQVVGpLTPEQKEVVSILDSSSRNLQKLI---EQLLDynrkqaDSAVEl 307
Cdd:PRK13559 166 LEAHERRLAREVDHRSKNVFA--------VVDSIVR-LTGRADDPSLYAAAIQERVQALArahETLLD------ERGWE- 229
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 308 dNVELAPLVETVVSAHSLPA-RAKMMHTDVDLKATAclAEPMLLmsVLDNLYSNAVHYGA---ESGNICL--RSSLHGAR 381
Cdd:PRK13559 230 -TVEVEELIRAQVAPYAPRAtRVAFEGPGIRLGAAS--VQPLGL--VLHELAVNAIKHGAlsaDQGRISIswKPSPEGAG 304
|
170
....*....|....*..
gi 1447699692 382 VYIDVINTGTPIPQEER 398
Cdd:PRK13559 305 FRIDWQEQGGPTPPKLA 321
|
|
| HATPase_CheA-like |
cd16916 |
Histidine kinase-like ATPase domain of the chemotaxis protein histidine kinase CheA, and some ... |
329-454 |
7.23e-04 |
|
Histidine kinase-like ATPase domain of the chemotaxis protein histidine kinase CheA, and some hybrid sensor histidine kinases; This family includes the cytoplasmic histidine kinase (HK) CheA, a transmembrane receptor which, together with cytoplasmic adaptor protein (CheW), forms the lattice at the core of the chemosensory array that controls the cellular chemotaxis of motile bacteria and archaea. CheA forms a two-component signal transduction system (TCS) with the response regulator CheY. Proteins having this CheA-like HATPase domain generally also have a histidine-phosphotransfer domain, a histidine kinase homodimeric domain, and a regulatory domain; some are hybrid sensor histidine kinases as they contain a REC signal receiver domain.
Pssm-ID: 340393 [Multi-domain] Cd Length: 178 Bit Score: 40.26 E-value: 7.23e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 329 AKMMHTDVDLKATAclAEPMLLMSVLDNLYS-------NAVHYGAES------------GNICLRSSLHGARVYIDV--- 386
Cdd:cd16916 13 ARELGKQVELVVEG--EDTELDKSVLEKLADplthllrNAVDHGIEApeerlaagkppeGTITLRAEHQGNQVVIEVsdd 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 387 -------------INTGTPIPQEERAM--------IFEPFFQGSHQrKGAVKGSGLGLSIARDCIRRMQGELYLVDESGQ 445
Cdd:cd16916 91 grgidrekirekaIERGLITADEAATLsddevlnlIFAPGFSTAEQ-VTDVSGRGVGMDVVKRSIESLGGTIEVESEPGQ 169
|
....*....
gi 1447699692 446 DVCFRIELP 454
Cdd:cd16916 170 GTTFTIRLP 178
|
|
| COG3920 |
COG3920 |
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction ... |
275-454 |
1.88e-03 |
|
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms];
Pssm-ID: 443125 [Multi-domain] Cd Length: 495 Bit Score: 40.66 E-value: 1.88e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 275 VVSILDSSSRNLQ-KLIEQLLD--YNRKQADSAV--------ELDNVELAPLVETVVSAHSLPARAKMMHTDVDL----- 338
Cdd:COG3920 313 VSSLLRLQARRADdPEAREALEesQNRIQALALVhellyqseDWEGVDLRDYLRELLEPLRDSYGGRGIRIELDGpdvel 392
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 339 ---KATAC---LAEpmllmsvldnLYSNAVHYGA---ESGNICLRSSLHGARVYIDVINTGTPIPQEeramiFEPffqgs 409
Cdd:COG3920 393 padAAVPLgliLNE----------LVTNALKHAFlsgEGGRIRVSWRREDGRLRLTVSDNGVGLPED-----VDP----- 452
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1447699692 410 hqrkgaVKGSGLGLSIARDCIRRMQGELYLVDESGqdVCFRIELP 454
Cdd:COG3920 453 ------PARKGLGLRLIRALVRQLGGTLELDRPEG--TRVRITFP 489
|
|
| HATPase_EL346-LOV-HK-like |
cd16951 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
324-452 |
4.46e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Erythrobacter litoralis blue light-activated histidine kinase 2; This domain family includes the histidine kinase-like ATPase (HATPase) domain of blue light-activated histidine kinase 2 of Erythrobacter litoralis (EL346). Signaling commonly occurs within HK dimers, however EL346 functions as a monomer. Also included in this family are the HATPase domains of ethanolamine utilization sensory transduction histidine kinase (EutW), whereby regulation of ethanolamine, a carbon and nitrogen source for gut bacteria, results in autophosphorylation and subsequent phosphoryl transfer to a response regulator (EutV) containing an RNA-binding domain. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory PAS sensor domain, while some have an N-terminal histidine kinase domain.
Pssm-ID: 340427 [Multi-domain] Cd Length: 131 Bit Score: 37.40 E-value: 4.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 324 SLPARAKMMHTDVDLKATACLAEPMLLMSVLDNLYSNAVHyGAESGNICLRSSLHGARVYIDVINTGTPIPQEeramiFE 403
Cdd:cd16951 18 VGDIRINITGDTGPVSSEVATAIGLVVNELLQNALKHAFS-DREGGTITIRSVVDGDYLRITVIDDGVGLPQD-----ED 91
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 1447699692 404 PFFQGShqrkgavkgsgLGLSIARDCIRRMQGELYLVD--ESGQDVCFRIE 452
Cdd:cd16951 92 WPNKGS-----------LGLQIVRSLVEGELKAFLEVQsaENGTRVNIDIP 131
|
|
| HAMP |
pfam00672 |
HAMP domain; |
177-230 |
7.12e-03 |
|
HAMP domain;
Pssm-ID: 459898 [Multi-domain] Cd Length: 53 Bit Score: 34.52 E-value: 7.12e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 1447699692 177 LFTRMIIGPVKNIERMINRLGEGRsLGNSVSFSGPSELRSVGQRILWLSERLSW 230
Cdd:pfam00672 1 LLARRILRPLRRLAEAARRIASGD-LDVRLPVSGRDEIGELARAFNQMAERLRE 53
|
|
| PRK11086 |
PRK11086 |
sensory histidine kinase DcuS; Provisional |
350-454 |
8.13e-03 |
|
sensory histidine kinase DcuS; Provisional
Pssm-ID: 236839 [Multi-domain] Cd Length: 542 Bit Score: 38.74 E-value: 8.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699692 350 LMSVLDNLYSNAVHY--GAESGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEpffQGsHQRKGavKGSGLGLSIAR 427
Cdd:PRK11086 434 LITILGNLIENALEAvgGEEGGEISVSLHYRNGWLHCEVSDDGPGIAPDEIDAIFD---KG-YSTKG--SNRGVGLYLVK 507
|
90 100
....*....|....*....|....*..
gi 1447699692 428 DCIRRMQGELYLVDESGQDVCFRIELP 454
Cdd:PRK11086 508 QSVENLGGSIAVESEPGVGTQFFVQIP 534
|
|
| |
