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Conserved domains on  [gi|15833100|ref|NP_311873|]
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transposase [Escherichia coli O157:H7 str. Sakai]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
IS66_access_TnpA NF038385
IS66-like element accessory protein TnpA;
12-206 6.09e-106

IS66-like element accessory protein TnpA;


:

Pssm-ID: 439678 [Multi-domain]  Cd Length: 190  Bit Score: 303.17  E-value: 6.09e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833100   12 FRSYLPDALRLRFEDKLTIRAIAQRLGLSHSTIHTLFQRFIASGIAWPLPDSVSLAQLDAILYANRKKELT-EPQISEGT 90
Cdd:NF038385   1 YRTLLLDALRLRFDESLSYRAIGRQLGVSKSTIHSLFQRFLRAGLSWPLPDSMSADQLDAALYPNRKKPPSaPTVTRPVV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833100   91 WRKERRTSYSREFKIRLVKQALQPGAVVARIAREHGINDNLLLKWKSQYEDGLLSDDDIQECMPVPVALTDTPEPTRPVT 170
Cdd:NF038385  81 WKKIRRPNFSREFKIRLVEQTLQPGACVAQIARENGINDNLLFNWRHLYRNGLLQPDNEQETALLPVTLTPEPDPTIPVP 160

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 15833100  171 NpfwrnkPDECPESDPGNVPRCELHLKSGVVKLFDP 206
Cdd:NF038385 161 A------QDPEQQNTTADSLCCELVLPAGTLRLFGP 190
 
Name Accession Description Interval E-value
IS66_access_TnpA NF038385
IS66-like element accessory protein TnpA;
12-206 6.09e-106

IS66-like element accessory protein TnpA;


Pssm-ID: 439678 [Multi-domain]  Cd Length: 190  Bit Score: 303.17  E-value: 6.09e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833100   12 FRSYLPDALRLRFEDKLTIRAIAQRLGLSHSTIHTLFQRFIASGIAWPLPDSVSLAQLDAILYANRKKELT-EPQISEGT 90
Cdd:NF038385   1 YRTLLLDALRLRFDESLSYRAIGRQLGVSKSTIHSLFQRFLRAGLSWPLPDSMSADQLDAALYPNRKKPPSaPTVTRPVV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833100   91 WRKERRTSYSREFKIRLVKQALQPGAVVARIAREHGINDNLLLKWKSQYEDGLLSDDDIQECMPVPVALTDTPEPTRPVT 170
Cdd:NF038385  81 WKKIRRPNFSREFKIRLVEQTLQPGACVAQIARENGINDNLLFNWRHLYRNGLLQPDNEQETALLPVTLTPEPDPTIPVP 160

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 15833100  171 NpfwrnkPDECPESDPGNVPRCELHLKSGVVKLFDP 206
Cdd:NF038385 161 A------QDPEQQNTTADSLCCELVLPAGTLRLFGP 190
HTH_Tnp_1 pfam01527
Transposase; Transposase proteins are necessary for efficient DNA transposition. This family ...
 93-171 2.17e-21

Transposase; Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.


Pssm-ID: 426308 [Multi-domain]  Cd Length: 75  Bit Score: 83.94  E-value: 2.17e-21
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15833100    93 KERRTSYSREFKIRLVKQALQPGAVVARIAREHGINDNLLLKWKSQYEDGLLSDDDIqecmPVPVALTDTPEPTRPVTN 171
Cdd:pfam01527   1 MKKRRRFSEEFKLRAVKEVLEPGRTVKEVARRHGVSPNTLYQWRRQYEGGMGASPAR----PRLTALEEENRRLKRELA 75
InsE COG2963
Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];
93-142 4.09e-15

Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442203 [Multi-domain]  Cd Length: 93  Bit Score: 68.03  E-value: 4.09e-15
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|
gi 15833100  93 KERRTSYSREFKIRLVKQALQPGAVVARIAREHGINDNLLLKWKSQYEDG 142
Cdd:COG2963   2 SKKRRRYSPEFKAEAVRLVLEGGASVAEVARELGISPSTLYRWVRQYREG 51
transpos_IS3 NF033516
IS3 family transposase;
102-147 1.96e-09

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 56.42  E-value: 1.96e-09
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 15833100  102 EFKIRLVKQALQPGAVVARIAREHGINDNLLLKWKSQYEDGLLSDD 147
Cdd:NF033516   1 EFKLEAVREVLEGGKSVAEVARELGISPSTLYRWRKKYRGGGEAAD 46
PRK09413 PRK09413
IS2 repressor TnpA; Reviewed
 89-145 7.57e-07

IS2 repressor TnpA; Reviewed


Pssm-ID: 181833  Cd Length: 121  Bit Score: 46.72  E-value: 7.57e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 15833100   89 GTWRKERRTSysrEFKIRLVKQALQPGAVVARIAREHGINDNLLLKWKSQYEDGLLS 145
Cdd:PRK09413   6 GPEKRRRRTT---QEKIAIVQQSFEPGMTVSLVARQHGVAASQLFLWRKQYQEGSLT 59
transpos_IS21 NF033546
IS21 family transposase;
20-51 1.55e-03

IS21 family transposase;


Pssm-ID: 468077 [Multi-domain]  Cd Length: 296  Bit Score: 38.73  E-value: 1.55e-03
                         10        20        30
                 ....*....|....*....|....*....|..
gi 15833100   20 LRLRFEDKLTIRAIAQRLGLSHSTIHTLFQRF 51
Cdd:NF033546   1 IRLLFRQGLSIREIARELGISRNTVRKYLRRA 32
 
Name Accession Description Interval E-value
IS66_access_TnpA NF038385
IS66-like element accessory protein TnpA;
12-206 6.09e-106

IS66-like element accessory protein TnpA;


Pssm-ID: 439678 [Multi-domain]  Cd Length: 190  Bit Score: 303.17  E-value: 6.09e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833100   12 FRSYLPDALRLRFEDKLTIRAIAQRLGLSHSTIHTLFQRFIASGIAWPLPDSVSLAQLDAILYANRKKELT-EPQISEGT 90
Cdd:NF038385   1 YRTLLLDALRLRFDESLSYRAIGRQLGVSKSTIHSLFQRFLRAGLSWPLPDSMSADQLDAALYPNRKKPPSaPTVTRPVV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833100   91 WRKERRTSYSREFKIRLVKQALQPGAVVARIAREHGINDNLLLKWKSQYEDGLLSDDDIQECMPVPVALTDTPEPTRPVT 170
Cdd:NF038385  81 WKKIRRPNFSREFKIRLVEQTLQPGACVAQIARENGINDNLLFNWRHLYRNGLLQPDNEQETALLPVTLTPEPDPTIPVP 160

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 15833100  171 NpfwrnkPDECPESDPGNVPRCELHLKSGVVKLFDP 206
Cdd:NF038385 161 A------QDPEQQNTTADSLCCELVLPAGTLRLFGP 190
HTH_Tnp_1 pfam01527
Transposase; Transposase proteins are necessary for efficient DNA transposition. This family ...
 93-171 2.17e-21

Transposase; Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.


Pssm-ID: 426308 [Multi-domain]  Cd Length: 75  Bit Score: 83.94  E-value: 2.17e-21
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15833100    93 KERRTSYSREFKIRLVKQALQPGAVVARIAREHGINDNLLLKWKSQYEDGLLSDDDIqecmPVPVALTDTPEPTRPVTN 171
Cdd:pfam01527   1 MKKRRRFSEEFKLRAVKEVLEPGRTVKEVARRHGVSPNTLYQWRRQYEGGMGASPAR----PRLTALEEENRRLKRELA 75
InsE COG2963
Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];
93-142 4.09e-15

Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442203 [Multi-domain]  Cd Length: 93  Bit Score: 68.03  E-value: 4.09e-15
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|
gi 15833100  93 KERRTSYSREFKIRLVKQALQPGAVVARIAREHGINDNLLLKWKSQYEDG 142
Cdd:COG2963   2 SKKRRRYSPEFKAEAVRLVLEGGASVAEVARELGISPSTLYRWVRQYREG 51
transpos_IS3 NF033516
IS3 family transposase;
102-147 1.96e-09

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 56.42  E-value: 1.96e-09
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 15833100  102 EFKIRLVKQALQPGAVVARIAREHGINDNLLLKWKSQYEDGLLSDD 147
Cdd:NF033516   1 EFKLEAVREVLEGGKSVAEVARELGISPSTLYRWRKKYRGGGEAAD 46
PRK09413 PRK09413
IS2 repressor TnpA; Reviewed
 89-145 7.57e-07

IS2 repressor TnpA; Reviewed


Pssm-ID: 181833  Cd Length: 121  Bit Score: 46.72  E-value: 7.57e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 15833100   89 GTWRKERRTSysrEFKIRLVKQALQPGAVVARIAREHGINDNLLLKWKSQYEDGLLS 145
Cdd:PRK09413   6 GPEKRRRRTT---QEKIAIVQQSFEPGMTVSLVARQHGVAASQLFLWRKQYQEGSLT 59
HTH_23 pfam13384
Homeodomain-like domain;
19-57 1.74e-04

Homeodomain-like domain;


Pssm-ID: 433164 [Multi-domain]  Cd Length: 50  Bit Score: 38.02  E-value: 1.74e-04
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 15833100    19 ALRLrFEDKLTIRAIAQRLGLSHSTIHTLFQRFIASGIA 57
Cdd:pfam13384  10 ALLL-LAEGLSVKEIAELLGVSRRTVYRWLKRYNEEGLE 47
HTH_40 pfam14493
Helix-turn-helix domain; This presumed domain is found at the C-terminus of a large number of ...
 24-108 8.26e-04

Helix-turn-helix domain; This presumed domain is found at the C-terminus of a large number of helicase proteins.


Pssm-ID: 464189  Cd Length: 89  Bit Score: 37.49  E-value: 8.26e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833100    24 FEDKLTIRAIAQRLGLSHSTIHTLFQRFIASGIAWPLPDSVSLAQLDAILYANRK---------KELTEPQIsegtwrke 94
Cdd:pfam14493   9 YKEGLSIEEIAEERGLKESTIEGHLAELIEAGEPVDIERLVSEEEQKEILDAIEKlgseslkpiKEALPEEI-------- 80

                          90
                  ....*....|....
gi 15833100    95 rrtSYsreFKIRLV 108
Cdd:pfam14493  81 ---SY---FEIRLV 88
transpos_IS21 NF033546
IS21 family transposase;
20-51 1.55e-03

IS21 family transposase;


Pssm-ID: 468077 [Multi-domain]  Cd Length: 296  Bit Score: 38.73  E-value: 1.55e-03
                         10        20        30
                 ....*....|....*....|....*....|..
gi 15833100   20 LRLRFEDKLTIRAIAQRLGLSHSTIHTLFQRF 51
Cdd:NF033546   1 IRLLFRQGLSIREIARELGISRNTVRKYLRRA 32
DeoR COG2390
DNA-binding transcriptional regulator LsrR, DeoR family [Transcription];
19-68 1.95e-03

DNA-binding transcriptional regulator LsrR, DeoR family [Transcription];


Pssm-ID: 441955 [Multi-domain]  Cd Length: 301  Bit Score: 38.57  E-value: 1.95e-03
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*
gi 15833100  19 ALRLRFEDKLTIRAIAQRLGLSHSTIHTLFQRFIASG-----IAWPLPDSVSLAQ 68
Cdd:COG2390   2 AAWLYYVEGLTQREIAERLGISRRTVSRLLAEAREEGlvrisITDPLAGLLELER 56
MarR_2 pfam12802
MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a ...
 22-55 4.38e-03

MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR. A large number of compounds induce transcription of the mar operon. This is thought to be due to the compound binding to MarR, and the resulting complex stops MarR binding to the DNA. With the MarR repression lost, transcription of the operon proceeds. The structure of MarR is known and shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif.


Pssm-ID: 432797 [Multi-domain]  Cd Length: 60  Bit Score: 34.49  E-value: 4.38e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 15833100    22 LRFEDKLTIRAIAQRLGLSHSTIHTLFQRFIASG 55
Cdd:pfam12802  14 LARNPGLTVAELARRLGISKQTVSRLVKRLEAKG 47
Csa3 COG3415
CRISPR-associated protein Csa3, CARF domain [Defense mechanisms]; CRISPR-associated protein ...
 22-57 9.61e-03

CRISPR-associated protein Csa3, CARF domain [Defense mechanisms]; CRISPR-associated protein Csa3, CARF domain is part of the Pathway/BioSystem: CRISPR-Cas system


Pssm-ID: 442641 [Multi-domain]  Cd Length: 325  Bit Score: 36.37  E-value: 9.61e-03
                        10        20        30
                ....*....|....*....|....*....|....*.
gi 15833100  22 LRFEDKLTIRAIAQRLGLSHSTIHTLFQRFIASGIA 57
Cdd:COG3415  33 LLLAEGLSVREIAERLGVSRSTVYRWLKRYREGGLA 68
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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