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Conserved domains on  [gi|15833676|ref|NP_312449|]
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dipeptide/heme ABC transporter permease [Escherichia coli O157:H7 str. Sakai]

Protein Classification

dipeptide ABC transporter permease DppC( domain architecture ID 11485083)

dipeptide ABC transporter permease DppC is the transmembrane subunit (TM) of the periplasmic binding protein (PBP)-dependent ABC transporter complex (DppABCDF) for dipeptide and is responsible for the translocation of the substrate across the membrane

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK10913 PRK10913
dipeptide ABC transporter permease DppC;
1-300 0e+00

dipeptide ABC transporter permease DppC;


:

Pssm-ID: 182833 [Multi-domain]  Cd Length: 300  Bit Score: 570.96  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676    1 MSQVTENKVISAPVPMTPLQEFWHYFKRNKGAVVGLVYVVIVLFIAIFANWIAPYNPAEQFRDALLAPPAWQEGGSMAHL 80
Cdd:PRK10913   1 MSQVTENKVISAPVPMTPLQEFWHYFKRNKGAVVGLVYVVIMLFIAIFANWIAPHNPAEQFRDALLAPPVWQEGGSWAHI 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676   81 LGTDDVGRDVLSRLMYGARLSLLVGCLVVVLSLIMGVILGLIAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPS 160
Cdd:PRK10913  81 LGTDDVGRDVLSRLMYGARLSLLVGCLVVVLSLVMGVILGLIAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPS 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676  161 IGNAALALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINIFPNCLAPLIVQASLGFSNAILDMAALGFL 240
Cdd:PRK10913 161 IVNAALALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINILPNCLAPLIVQASLGFSNAILDMAALGFL 240
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676  241 GMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGLAILLTVLAFNLMGDGLRDALDPKLKQ 300
Cdd:PRK10913 241 GMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGLAILLTVLAFNLMGDGLRDALDPKLKQ 300
 
Name Accession Description Interval E-value
PRK10913 PRK10913
dipeptide ABC transporter permease DppC;
1-300 0e+00

dipeptide ABC transporter permease DppC;


Pssm-ID: 182833 [Multi-domain]  Cd Length: 300  Bit Score: 570.96  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676    1 MSQVTENKVISAPVPMTPLQEFWHYFKRNKGAVVGLVYVVIVLFIAIFANWIAPYNPAEQFRDALLAPPAWQEGGSMAHL 80
Cdd:PRK10913   1 MSQVTENKVISAPVPMTPLQEFWHYFKRNKGAVVGLVYVVIMLFIAIFANWIAPHNPAEQFRDALLAPPVWQEGGSWAHI 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676   81 LGTDDVGRDVLSRLMYGARLSLLVGCLVVVLSLIMGVILGLIAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPS 160
Cdd:PRK10913  81 LGTDDVGRDVLSRLMYGARLSLLVGCLVVVLSLVMGVILGLIAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPS 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676  161 IGNAALALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINIFPNCLAPLIVQASLGFSNAILDMAALGFL 240
Cdd:PRK10913 161 IVNAALALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINILPNCLAPLIVQASLGFSNAILDMAALGFL 240
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676  241 GMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGLAILLTVLAFNLMGDGLRDALDPKLKQ 300
Cdd:PRK10913 241 GMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGLAILLTVLAFNLMGDGLRDALDPKLKQ 300
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
15-295 9.01e-104

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 303.96  E-value: 9.01e-104
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676  15 PMTPLQEFWHYFKRNKGAVVGLVYVVIVLFIAIFANWIAPYNPAEQFRDALLAPPawqeggSMAHLLGTDDVGRDVLSRL 94
Cdd:COG1173   1 PRSRWRRAWRRLRRNPLAVIGLVILLLLVLLALFAPLLAPYDPTAQDLAARLQPP------SAAHWLGTDQLGRDVLSRL 74
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676  95 MYGARLSLLVGCLVVVLSLIMGVILGLIAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPSIGNAALALTFVALP 174
Cdd:COG1173  75 LYGARISLLVGLLAVLIALVIGVLLGLLAGYFGGWVDAVLMRLVDVLLAFPSLLLAIALVAVLGPGLLNVILALGLTGWP 154
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676 175 HYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINIFPNCLAPLIVQASLGFSNAILDMAALGFLGMGAQPPTPEWGTM 254
Cdd:COG1173 155 GYARLVRAQVLSLREREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAILAEAGLSFLGLGVQPPTPSWGTM 234
                       250       260       270       280
                ....*....|....*....|....*....|....*....|.
gi 15833676 255 LSDVLQFAQSAWWVVTFPGLAILLTVLAFNLMGDGLRDALD 295
Cdd:COG1173 235 LSEGRNYLLTAPWLALFPGLAIVLTVLAFNLLGDGLRDALD 275
nickel_nikC TIGR02790
nickel ABC transporter, permease subunit NikC; This family consists of the NikC family of ...
44-295 1.33e-69

nickel ABC transporter, permease subunit NikC; This family consists of the NikC family of nickel ABC transporter permeases. Operons that contain this protein also contain a homologous permease subunit NikB. Nickel is used in cells as part of urease or certain hydrogenases or superoxide dismutases. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131837 [Multi-domain]  Cd Length: 258  Bit Score: 216.48  E-value: 1.33e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676    44 FIAIFANWIAPYNPAEQFRDALLAPPAWQeggsmaHLLGTDDVGRDVLSRLMYGARLSLLVGCLVVVLSLIMGVILGLIA 123
Cdd:TIGR02790  13 LLAIFAPWIAPHDPLAQNLPMRLLGPSME------YWLGTDHLGRCIFSRLIFGARVSLGSALLVLGLVLTIGLLIGGLA 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676   124 GYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPSIGNAALALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGA 203
Cdd:TIGR02790  87 GYIGGRVDEAIMRVCDVFLSFPTIILSLAIVGILGPGLENVIIAIVLVHWAWYARMVRGMVVSLKQREFVLAARTSGASH 166
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676   204 MRQMFINIFPNCLAPLIVQASLGFSNAILDMAALGFLGMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGLAILLTVLAF 283
Cdd:TIGR02790 167 WQIIRRHILPNILSPIIVLATLDIGHVILHIAGLSFLGLGIQPPTPEWGAMLSEAKQYIWTQPLLMIYPGLAILISVMAF 246
                         250
                  ....*....|..
gi 15833676   284 NLMGDGLRDALD 295
Cdd:TIGR02790 247 NLLGDALRDHLG 258
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
114-280 3.32e-14

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 69.61  E-value: 3.32e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676 114 IMGVILGLIAGYFGGLVDNIIMRVVDIMLA--------LPSLLLALVLVAIFGPSIGNAALALTFVALPHYVRLTRAAVL 185
Cdd:cd06261  17 VLGLLLGIILARKRGKLDRLLRRIIDLLLSlpslvlglLLVLLFGVLLGWGILPGLGLPALILALLLIAPFARLIRRAAL 96
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676 186 VEVNRDYVTASRVAGAGAMRQMFINIFPNCLAPLIVQASLGFSNAILDMAALGFLGMGAqPPTPEWGTMLsdVLQFAQSA 265
Cdd:cd06261  97 ESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGE-APGPGTGLLL--IFAILFPG 173
                       170
                ....*....|....*
gi 15833676 266 WWVVTFPGLAILLTV 280
Cdd:cd06261 174 DLGVAAAVALILLLL 188
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
116-300 1.57e-13

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 67.71  E-value: 1.57e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676   116 GVILGLIAG-YFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPSI----GNAALALTFVALPHYVRLTRAAVLVEVNR 190
Cdd:pfam00528   1 GIPLGIIAAlRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSIlghgILPAIILALLGWAGYARLIRRAALRSLPS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676   191 DYVTASRVAGAGAMRQMFINIFPNCLAPLIVQASLGFSNAILDMAALGFL----GMGAQPPTPEWGTMLSdvlqfaqsaw 266
Cdd:pfam00528  81 DLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLgswpGLGLLLIEAILGYDYP---------- 150
                         170       180       190
                  ....*....|....*....|....*....|....
gi 15833676   267 wVVTFPGLAILLTVLAFNLMGDGLRDALDPKLKQ 300
Cdd:pfam00528 151 -EIQGPVLAAALILLLLNLLVDILQRLLDPRVRK 183
 
Name Accession Description Interval E-value
PRK10913 PRK10913
dipeptide ABC transporter permease DppC;
1-300 0e+00

dipeptide ABC transporter permease DppC;


Pssm-ID: 182833 [Multi-domain]  Cd Length: 300  Bit Score: 570.96  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676    1 MSQVTENKVISAPVPMTPLQEFWHYFKRNKGAVVGLVYVVIVLFIAIFANWIAPYNPAEQFRDALLAPPAWQEGGSMAHL 80
Cdd:PRK10913   1 MSQVTENKVISAPVPMTPLQEFWHYFKRNKGAVVGLVYVVIMLFIAIFANWIAPHNPAEQFRDALLAPPVWQEGGSWAHI 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676   81 LGTDDVGRDVLSRLMYGARLSLLVGCLVVVLSLIMGVILGLIAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPS 160
Cdd:PRK10913  81 LGTDDVGRDVLSRLMYGARLSLLVGCLVVVLSLVMGVILGLIAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPS 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676  161 IGNAALALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINIFPNCLAPLIVQASLGFSNAILDMAALGFL 240
Cdd:PRK10913 161 IVNAALALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINILPNCLAPLIVQASLGFSNAILDMAALGFL 240
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676  241 GMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGLAILLTVLAFNLMGDGLRDALDPKLKQ 300
Cdd:PRK10913 241 GMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGLAILLTVLAFNLMGDGLRDALDPKLKQ 300
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
15-295 9.01e-104

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 303.96  E-value: 9.01e-104
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676  15 PMTPLQEFWHYFKRNKGAVVGLVYVVIVLFIAIFANWIAPYNPAEQFRDALLAPPawqeggSMAHLLGTDDVGRDVLSRL 94
Cdd:COG1173   1 PRSRWRRAWRRLRRNPLAVIGLVILLLLVLLALFAPLLAPYDPTAQDLAARLQPP------SAAHWLGTDQLGRDVLSRL 74
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676  95 MYGARLSLLVGCLVVVLSLIMGVILGLIAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPSIGNAALALTFVALP 174
Cdd:COG1173  75 LYGARISLLVGLLAVLIALVIGVLLGLLAGYFGGWVDAVLMRLVDVLLAFPSLLLAIALVAVLGPGLLNVILALGLTGWP 154
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676 175 HYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINIFPNCLAPLIVQASLGFSNAILDMAALGFLGMGAQPPTPEWGTM 254
Cdd:COG1173 155 GYARLVRAQVLSLREREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAILAEAGLSFLGLGVQPPTPSWGTM 234
                       250       260       270       280
                ....*....|....*....|....*....|....*....|.
gi 15833676 255 LSDVLQFAQSAWWVVTFPGLAILLTVLAFNLMGDGLRDALD 295
Cdd:COG1173 235 LSEGRNYLLTAPWLALFPGLAIVLTVLAFNLLGDGLRDALD 275
SapC COG4171
ABC-type antimicrobial peptide export system, permease component SapC [Defense mechanisms];
17-299 1.80e-83

ABC-type antimicrobial peptide export system, permease component SapC [Defense mechanisms];


Pssm-ID: 443331 [Multi-domain]  Cd Length: 296  Bit Score: 253.20  E-value: 1.80e-83
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676  17 TPLQEFWHYFKRNKGAVVGLVYVVIVLFIAIFANWIAPYNPAEQFRDALLAPPAWQEGGSMAHLLGTDDVGRDVLSRLMY 96
Cdd:COG4171  14 SPLKQIWQSFRKNPLAMIGLYGFLFLILLALFGPLLAPYSPDQQFIGALLLPPSWDDNGDVSFFLGTDDLGRDILSRLLY 93
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676  97 GARLSLLVGCLVVVLSLIMGVILGLIAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPSIGNAALALTFVALPHY 176
Cdd:COG4171  94 GARYTFGSALLVVLAAAIIGGIIGILAGMSRGLKSSILNHLLDTLLSIPSLLLAIIIVALLGPGLENAMLAITLALLPQF 173
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676 177 VRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINIFPNCLAPLIVQASLGFSNAILDMAALGFLGMGAQPPTPEWGTMLS 256
Cdd:COG4171 174 IHAIYQAVHQELKKEYVLAARLDGASNWQLLRYSILPNILEVLVTELTRALSIAILDISALGFLGLGAQLPSPEWGAMLG 253
                       250       260       270       280
                ....*....|....*....|....*....|....*....|...
gi 15833676 257 DVLQFAQSAWWVVTFPGLAILLTVLAFNLMGDGLRDALDPKLK 299
Cdd:COG4171 254 DSLELIYLAPWTVILPGLAIMFSVLIVNLVGDGLRRALNKGVE 296
nickel_nikC TIGR02790
nickel ABC transporter, permease subunit NikC; This family consists of the NikC family of ...
44-295 1.33e-69

nickel ABC transporter, permease subunit NikC; This family consists of the NikC family of nickel ABC transporter permeases. Operons that contain this protein also contain a homologous permease subunit NikB. Nickel is used in cells as part of urease or certain hydrogenases or superoxide dismutases. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131837 [Multi-domain]  Cd Length: 258  Bit Score: 216.48  E-value: 1.33e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676    44 FIAIFANWIAPYNPAEQFRDALLAPPAWQeggsmaHLLGTDDVGRDVLSRLMYGARLSLLVGCLVVVLSLIMGVILGLIA 123
Cdd:TIGR02790  13 LLAIFAPWIAPHDPLAQNLPMRLLGPSME------YWLGTDHLGRCIFSRLIFGARVSLGSALLVLGLVLTIGLLIGGLA 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676   124 GYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPSIGNAALALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGA 203
Cdd:TIGR02790  87 GYIGGRVDEAIMRVCDVFLSFPTIILSLAIVGILGPGLENVIIAIVLVHWAWYARMVRGMVVSLKQREFVLAARTSGASH 166
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676   204 MRQMFINIFPNCLAPLIVQASLGFSNAILDMAALGFLGMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGLAILLTVLAF 283
Cdd:TIGR02790 167 WQIIRRHILPNILSPIIVLATLDIGHVILHIAGLSFLGLGIQPPTPEWGAMLSEAKQYIWTQPLLMIYPGLAILISVMAF 246
                         250
                  ....*....|..
gi 15833676   284 NLMGDGLRDALD 295
Cdd:TIGR02790 247 NLLGDALRDHLG 258
PRK09881 PRK09881
D,D-dipeptide ABC transporter permease;
43-298 7.19e-68

D,D-dipeptide ABC transporter permease;


Pssm-ID: 182131 [Multi-domain]  Cd Length: 296  Bit Score: 213.53  E-value: 7.19e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676   43 LFIAIFANWIAPYNPAEQFRDALLAPPawqeggSMAHLLGTDDVGRDVLSRLMYGARLSLLVGCLVVVLSLIMGVILGLI 122
Cdd:PRK09881  44 LLMMIFSPWLATHDPNAIDLTARLLPP------SAAHWFGTDEVGRDLFSRVLVGSQQSILAGLVVVAIAGMIGSLLGCL 117
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676  123 AGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPSIGNAALALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAG 202
Cdd:PRK09881 118 SGVLGGRADAIIMRIMDIMLSIPSLVLTMALAAALGPSLFNAMLAIAIVRIPFYVRLARGQALVVRQYTYVQAAKTFGAS 197
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676  203 AMRQMFINIFPNCLAPLIVQASLGFSNAILDMAALGFLGMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGLAILLTVLA 282
Cdd:PRK09881 198 RWHLISWHILRNSLPPLIVQASLDIGSAILMAATLGFIGLGAQQPSAEWGAMVANGRNYVLDQWWYCAFPGAAILLTAVG 277
                        250
                 ....*....|....*.
gi 15833676  283 FNLMGDGLRDALDPKL 298
Cdd:PRK09881 278 FNLFGDGIRDLLDPKA 293
PRK15082 PRK15082
glutathione ABC transporter permease GsiD; Provisional
17-300 2.61e-65

glutathione ABC transporter permease GsiD; Provisional


Pssm-ID: 185040 [Multi-domain]  Cd Length: 301  Bit Score: 206.89  E-value: 2.61e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676   17 TPLQEFWHYFKRNKGAVVGLVYVVIVLFIAIFANWIAPYNPAEQFR-DALLAPPawqeggSMAHLLGTDDVGRDVLSRLM 95
Cdd:PRK15082  23 TPWHEFWRRFRRQHVALVAGLFVLLLIVVAIFAPWIAPYDAENYFDyDALNAGP------SLQHWFGVDSLGRDIFSRIL 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676   96 YGARLSLLVGCLVVVLSLIMGVILGLIAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPSIGNAALALTFVALPH 175
Cdd:PRK15082  97 VGARISLAAGFFSVAIGAAIGTVLGLLAGYYEGWWDRIIMRICDVLFAFPGILLAIAVVAILGSGMANVIIAVAIFSIPA 176
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676  176 YVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINIFPNCLAPLIVQASLGFSNAILDMAALGFLGMGAQPPTPEWGTML 255
Cdd:PRK15082 177 FARLVRGNTLVLKQQTYIESARSIGASDWTILLRHILPGTVSSIVVYFTMRIGTSIITAASLSFLGLGAQPPTPEWGAML 256
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 15833676  256 SDVLQFAQSAWWVVTFPGLAILLTVLAFNLMGDGLRDALDPKLKQ 300
Cdd:PRK15082 257 NEARADMVIAPHVALFPSLAIFLTVLAFNLLGDGLRDALDPKIKG 301
PRK15111 PRK15111
peptide ABC transporter permease SapC;
15-295 4.78e-58

peptide ABC transporter permease SapC;


Pssm-ID: 185066 [Multi-domain]  Cd Length: 296  Bit Score: 187.99  E-value: 4.78e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676   15 PMTPLQEFWHYFKRNKGAVVGLVYVVIVLFIAIFANWIAPYNPAEQFRDALLAPPAWQEGGSMAHLLGTDDVGRDVLSRL 94
Cdd:PRK15111  12 PPGTLRTAWRKFYSDALAMVGLYGCAGLALLCLFGGWLAPYGIDQQFLGYQLLPPSWSRYGEVSFFLGTDDLGRDVLSRL 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676   95 MYGARLSLLVGCLVVVLSLIMGVILGLIAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPSIGNAALALTFVALP 174
Cdd:PRK15111  92 LSGAAPTVGGAFVVTLAATLCGLVLGVFAGATHGLRSAVLNHILDTLLSIPSLLLAIIVVAFAGPSLSHAMFAVWLALLP 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676  175 HYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINIFPNCLAPLIVQASLGFSNAILDMAALGFLGMGAQPPTPEWGTM 254
Cdd:PRK15111 172 RMVRSIYSAVHDELEKEYVIAARLDGASTLNILWYAVLPNITAGLVTEITRALSMAILDIAALGFLDLGAQLPSPEWGAM 251
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 15833676  255 LSDVLQFAQSAWWVVTFPGLAILLTVLAFNLMGDGLRDALD 295
Cdd:PRK15111 252 LGDSLELIYVAPWTVMLPGAAIMLSVLLVNLLGDGIRRAII 292
nikC PRK10417
nickel transporter permease NikC; Provisional
45-299 1.30e-57

nickel transporter permease NikC; Provisional


Pssm-ID: 236687 [Multi-domain]  Cd Length: 272  Bit Score: 186.03  E-value: 1.30e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676   45 IAIFANWIAPYNPAEQFRDALLAPPAWQeggsmaHLLGTDDVGRDVLSRLMYGARLSLLVGCLVVVLSLIMGVILGLIAG 124
Cdd:PRK10417  19 IALTSQWWLPYDPQAIDLPSRLLSPDAQ------HWLGTDHLGRDIFSRLMAGTRVSLGSVMACLLLVLALGLVIGGSAG 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676  125 YFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPSIGNAALAltfVALPH---YVRLTRAAVLVEVNRDYVTASRVAGA 201
Cdd:PRK10417  93 LLGGRVDQATMRVADMFMTFPTSILAFFMVGVLGTGLTNVIIA---IALSHwawYARMVRSLVISLRQREFVLAARLSGA 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676  202 GAMRQMFINIFPNCLAPLIVQASLGFSNAILDMAALGFLGMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGLAILLTVL 281
Cdd:PRK10417 170 GHVRVFIDHLLPAVIPQLLVLATLDIGHMMLHVAGLSFLGLGVTAPTAEWGVMINDARQYIWTQPLLMFWPGLALFISVM 249
                        250
                 ....*....|....*...
gi 15833676  282 AFNLMGDGLRDALDPKLK 299
Cdd:PRK10417 250 AFNLLGDALRDHLDPHLV 267
YejE COG4239
ABC-type microcin C transport system, permease component YejE [Secondary metabolites ...
54-297 6.31e-39

ABC-type microcin C transport system, permease component YejE [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443381 [Multi-domain]  Cd Length: 342  Bit Score: 139.52  E-value: 6.31e-39
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676  54 PYNPAEQFRDALLAPPAwqeGGSMAHLLGTDDVGRDVLSRLMYGARLSLLVGCLVVVLSLIMGVILGLIAGYFGGLVDNI 133
Cdd:COG4239  99 PYSYDTINYDLPSPAPS---PPSAENWLGTDDQGRDVLARLIYGFRISVLFGLALTVISSVIGVAAGAVQGYFGGRVDLL 175
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676 134 IMRVVDIMLALPSLLLALVLVAIFGPSIGNAALALTF---VALPHYVrltRAAVLVEVNRDYVTASRVAGAGAMRQMFIN 210
Cdd:COG4239 176 FQRFIEIWSSMPELYLLIILSSIFQPSFWLLLGILLLfgwMGLVGVV---RAEFLRARNLEYVRAARALGVSDRRIMFRH 252
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676 211 IFPNCLAPLIVQASLGFSNAILDMAALGFLGMGAQPPTPEWGTMLS---DVLQfaqsAWWVV--TFPGLAILLTVLAFnl 285
Cdd:COG4239 253 ILPNAMVATLTFLPFILSGAITTLTSLDFLGFGLPPGSPSLGELLAqgkNNLQ----APWLGlsAFVVLALMLSLLVF-- 326
                       250
                ....*....|..
gi 15833676 286 MGDGLRDALDPK 297
Cdd:COG4239 327 IGEAVRDAFDPR 338
PRK15406 PRK15406
oligopeptide ABC transporter permease OppC; Provisional
26-297 6.44e-36

oligopeptide ABC transporter permease OppC; Provisional


Pssm-ID: 185304 [Multi-domain]  Cd Length: 302  Bit Score: 130.73  E-value: 6.44e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676   26 FKRNKGAVVGLVYVVIVLFIAIFANWIAPYNPAEQFRDALLAPPAWQEGgsmaHLLGTDDVGRDVLSRLMYGARLSLLVG 105
Cdd:PRK15406  33 FMHNRAAVASLIVLVLIALFVILAPMLSQFAYDDTDWGMMSSAPDMESG----HYFGTDSSGRDLLVRVAIGGRISLMVG 108
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676  106 CLVVVLSLIMGVILGLIAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPSIGNAALALTFVALPHYVRLTRAAVL 185
Cdd:PRK15406 109 VAAALVAVVVGTLYGSLSGYLGGKVDSVMMRLLEILNSFPFMFFVILLVTFFGQNILLIFVAIGMVSWLDMARIVRGQTL 188
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676  186 VEVNRDYVTASRVAGAGAMRQMFINIFPNCLAPLIVQASLGFSNAILDMAALGFLGMGAQPPTPEWGTMLSDVLQFAQSA 265
Cdd:PRK15406 189 SLKRKEFIEAAQVGGVSTRGIVLRHIVPNVLGVVVVYASLLVPSMILFESFLSFLGLGTQEPLSSWGALLSDGANSMEVS 268
                        250       260       270
                 ....*....|....*....|....*....|..
gi 15833676  266 WWVVTFPGLAILLTVLAFNLMGDGLRDALDPK 297
Cdd:PRK15406 269 PWLLLFPAGFLVVTLFCFNFIGDGLRDALDPK 300
PRK15021 PRK15021
microcin C ABC transporter permease; Provisional
67-296 1.28e-19

microcin C ABC transporter permease; Provisional


Pssm-ID: 184982 [Multi-domain]  Cd Length: 341  Bit Score: 87.35  E-value: 1.28e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676   67 APPAWQeggsmaHLLGTDDVGRDVLSRLMYGARLSLLVGCLVVVLSLIMGVILGLIAGYFGGLVDNIIMRVVDIMLALPS 146
Cdd:PRK15021 115 SPPSRQ------NWLGTDANGGDVLARILYGTRISVLFGLMLTLCSSVMGVLAGALQGYYGGKVDLWGQRFIEVWSGMPT 188
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676  147 LLLALVLVAIFGPSIGnAALALTFV-ALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINIFPNCLAPLIVQASL 225
Cdd:PRK15021 189 LFLIILLSSVVQPNFW-WLLAITVLfGWMSLVGVVRAEFLRTRNFDYIRAAQALGVSDRSIILRHMLPNAMVATLTFLPF 267
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15833676  226 GFSNAILDMAALGFLGMGAQPPTPEWGTMLSDVLQFAQSAWWVVT-FPGLAILLTVLAFnlMGDGLRDALDP 296
Cdd:PRK15021 268 ILCSSITTLTSLDFLGFGLPLGSPSLGELLLQGKNNLQAPWLGITaFLSVAILLSLLIF--IGEAVRDAFDP 337
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
114-280 3.32e-14

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 69.61  E-value: 3.32e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676 114 IMGVILGLIAGYFGGLVDNIIMRVVDIMLA--------LPSLLLALVLVAIFGPSIGNAALALTFVALPHYVRLTRAAVL 185
Cdd:cd06261  17 VLGLLLGIILARKRGKLDRLLRRIIDLLLSlpslvlglLLVLLFGVLLGWGILPGLGLPALILALLLIAPFARLIRRAAL 96
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676 186 VEVNRDYVTASRVAGAGAMRQMFINIFPNCLAPLIVQASLGFSNAILDMAALGFLGMGAqPPTPEWGTMLsdVLQFAQSA 265
Cdd:cd06261  97 ESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGE-APGPGTGLLL--IFAILFPG 173
                       170
                ....*....|....*
gi 15833676 266 WWVVTFPGLAILLTV 280
Cdd:cd06261 174 DLGVAAAVALILLLL 188
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
116-300 1.57e-13

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 67.71  E-value: 1.57e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676   116 GVILGLIAG-YFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPSI----GNAALALTFVALPHYVRLTRAAVLVEVNR 190
Cdd:pfam00528   1 GIPLGIIAAlRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSIlghgILPAIILALLGWAGYARLIRRAALRSLPS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676   191 DYVTASRVAGAGAMRQMFINIFPNCLAPLIVQASLGFSNAILDMAALGFL----GMGAQPPTPEWGTMLSdvlqfaqsaw 266
Cdd:pfam00528  81 DLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLgswpGLGLLLIEAILGYDYP---------- 150
                         170       180       190
                  ....*....|....*....|....*....|....
gi 15833676   267 wVVTFPGLAILLTVLAFNLMGDGLRDALDPKLKQ 300
Cdd:pfam00528 151 -EIQGPVLAAALILLLLNLLVDILQRLLDPRVRK 183
OppC_N pfam12911
N-terminal TM domain of oligopeptide transport permease C; Oligopeptide permeases (Opp) have ...
17-69 6.99e-08

N-terminal TM domain of oligopeptide transport permease C; Oligopeptide permeases (Opp) have been identified in numerous gram-negative and -positive bacteria. These transport systems belong to the superfamily of highly conserved ATP-binding cassette transporters. Typically, Opp importers comprise a complex of five proteins. The oligopeptide-binding protein OppA is responsible for the capture of peptides from the external medium. Two integral highly hydrophobic membrane spanning proteins, OppB and OppC, form a channel through the membrane used for peptide translocation. This N-terminal domain appears to be the first TM domain of the molecule.


Pssm-ID: 463747 [Multi-domain]  Cd Length: 53  Bit Score: 48.18  E-value: 6.99e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 15833676    17 TPLQEFWHYFKRNKGAVVGLVYVVIVLFIAIFANWIAPYNPAEQFRDALLAPP 69
Cdd:pfam12911   1 SPWQDAWRRFRRNKLAMVGLVILLLLVLLAIFAPLLAPYDPDQQDLSADLLPP 53
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
165-231 1.68e-05

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 45.44  E-value: 1.68e-05
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15833676 165 ALALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINIFPNCLAPLIVQASLGFSNAI 231
Cdd:COG0601 185 ALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPVVTVLGLQLGGLL 251
cysT CHL00187
sulfate transport protein; Provisional
165-231 4.22e-03

sulfate transport protein; Provisional


Pssm-ID: 214388 [Multi-domain]  Cd Length: 237  Bit Score: 38.07  E-value: 4.22e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15833676  165 ALALTFVALPHYVRlTRAAVLVEVNRDYVTASRVAGAGAMRQMFINIFPNCLAPLIVQASLGFSNAI 231
Cdd:CHL00187 141 LLAMIFVSFPFVVR-TIQPVLQEIEKELEEAAWSLGASPWQTFWKVIFPPLIPALLTGLALTFSRAI 206
Mo_ABC_porter TIGR01581
NifC-like ABC-type porter; This model describes a clade of ABC porter genes with relatively ...
166-278 9.49e-03

NifC-like ABC-type porter; This model describes a clade of ABC porter genes with relatively weak homology compared to its neighbor clades, the molybdate (TIGR02141) and sulfate (TIGR00969) porters. Neighbor-Joining, PAM-distance phylogenetic trees support the separation of the clades in this way. Included in this group is a gene designated NifC in Clostridium pasturianum. It would be reasonable to presume that NifC acts as a molybdate porter since the most common form of nitrogenase is a molybdoenzyme. Several other sequences falling within the scope of this model are annotated as molybdate porters and one, from Halobacterium, is annotated as a sulfate porter. There is presently no experimental evidence to support annotations with this degree of specificity.


Pssm-ID: 130643  Cd Length: 225  Bit Score: 36.61  E-value: 9.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833676   166 LALTFVALPHYVRLTRAAVlVEVNRDYVTASRVAGAGAMrQMFINI-FPNCLAPLIVQASLGFSNAILDMAALGFLGMGA 244
Cdd:TIGR01581 108 LAQTFVASPYYVRVARSTF-KSVDPRYEDVARSLGAGPL-ETFRKItLPMARPGLLAGLVLAWARALGEFGATLMFAGSI 185
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 15833676   245 QP-----PTPEWGTMLSDVLQFA-QSAWWVVTFPGLAILL 278
Cdd:TIGR01581 186 QGktrtlPLAIYLNIQSDNIEAAvASALLLLVIAFLLLLV 225
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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