NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|15833680|ref|NP_312453|]
View 

fimbrial adhesin protein [Escherichia coli O157:H7 str. Sakai]

Protein Classification

fimbrial protein( domain architecture ID 646)

fimbrial protein similar to the type-1 fimbrial major subunit FimA, which is transported to the outer membrane by the lipoprotein sorting system, and a mature or processed FimA protein on the outer membrane is autopolymerized to form Fim fimbriae

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Fimbrial super family cl01416
Fimbrial protein;
1-176 2.34e-97

Fimbrial protein;


The actual alignment was detected with superfamily member PRK15205:

Pssm-ID: 445401  Cd Length: 176  Bit Score: 279.04  E-value: 2.34e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833680    1 MKFKRLLHSGiASLSLVACGVNAATDLGPAGDIHFSITITTKACEMEKSDLEVDMGTMTLQKPAAVGTVLSKKDFTIELK 80
Cdd:PRK15205   1 MKNKRALLPL-ALLLLTASGMAAPTDLGPAGDIHFTITIKAKACELEKDSLEVDMGTMVLQKPVKVGTELNQKNFSIGLK 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833680   81 ECDGISKATVEMDSQSDSDDDSMFALEAGGATGVALKIEDDKGTQQVPKGSSGTPIEWAIDGE-TTSLHYQASYVVVNTQ 159
Cdd:PRK15205  80 DCDGISKASVTMDGSPDPDDPSLFALDAGGATGVALKIKTSKGTQQYPKSTDGTPVEWAINGDgTTQLNYIASYVPVNAD 159

                        170
                 ....*....|....*..
gi 15833680  160 ATGGTANALVNFSITYE 176
Cdd:PRK15205 160 ATVGTANATVNFSVTYE 176
 
Name Accession Description Interval E-value
PRK15205 PRK15205
long polar fimbrial protein LpfE; Provisional
 1-176 2.34e-97

long polar fimbrial protein LpfE; Provisional


Pssm-ID: 237923  Cd Length: 176  Bit Score: 279.04  E-value: 2.34e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833680    1 MKFKRLLHSGiASLSLVACGVNAATDLGPAGDIHFSITITTKACEMEKSDLEVDMGTMTLQKPAAVGTVLSKKDFTIELK 80
Cdd:PRK15205   1 MKNKRALLPL-ALLLLTASGMAAPTDLGPAGDIHFTITIKAKACELEKDSLEVDMGTMVLQKPVKVGTELNQKNFSIGLK 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833680   81 ECDGISKATVEMDSQSDSDDDSMFALEAGGATGVALKIEDDKGTQQVPKGSSGTPIEWAIDGE-TTSLHYQASYVVVNTQ 159
Cdd:PRK15205  80 DCDGISKASVTMDGSPDPDDPSLFALDAGGATGVALKIKTSKGTQQYPKSTDGTPVEWAINGDgTTQLNYIASYVPVNAD 159

                        170
                 ....*....|....*..
gi 15833680  160 ATGGTANALVNFSITYE 176
Cdd:PRK15205 160 ATVGTANATVNFSVTYE 176
FimA COG3539
Pilin (type 1 fimbrial protein) [Cell motility];
11-176 1.42e-29

Pilin (type 1 fimbrial protein) [Cell motility];


Pssm-ID: 442760 [Multi-domain]  Cd Length: 172  Bit Score: 106.66  E-value: 1.42e-29
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833680  11 IASLSLVACGVNAATDLGPAGDIHFSITITTKACE--MEKSDLEVDMGTMTLQKPAAVGTVLSKKDFTIELKECDGISKA 88
Cdd:COG3539   4 LLLALLLALALSAAAAAAADGTVNFTGTVVAPTCTinTGSKDQTVDLGTVSTSDLNGVGSTSGPKPFSIKLTNCDAGTSN 83

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833680  89 TVEM--DSQSDSDDDSMFAL-EAGGATGVALKIEDDKGTqQVPKGSSGTPIEWAIDGETTsLHYQASYVVVNTQATGGTA 165
Cdd:COG3539  84 SVKVtfTGTADSANPGLLANtGSGGASGVGIQLLDSDGT-PIPLGTPSSAVTLTSNGSAT-LPFYARYVATGATVTAGSF 161

                       170
                ....*....|.
gi 15833680 166 NALVNFSITYE 176
Cdd:COG3539 162 NATATFTIDYQ 172
Fimbrial pfam00419
Fimbrial protein;
33-176 3.82e-10

Fimbrial protein;


Pssm-ID: 425671  Cd Length: 152  Bit Score: 55.52  E-value: 3.82e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833680    33 IHFSITITTK--ACEMEKSD-LEVDMGTMTLQKPAAVGTVLSKKDFTIELkECDGIS---KATVEMDSQSDSDDDSMFAL 106
Cdd:pfam00419   1 INFTGTVTRVpaTCKITAGTpIEVDFGQIPVNELNAGGEGSRQKPFSITL-ECSSGSsavKVTVGLFGTADASSPNLLLT 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15833680   107 --EAGGATGVALKIEDDKGTqQVPKGSSGTPIEWAID-GETTSLHYQASYVVVNTQA-TGGTANALVNFSITYE 176
Cdd:pfam00419  80 gnGAGAATGVGIRLYDANGG-ALPPNNGTSSIPVSATaAVATGITFTASLVATTGGTpTAGDFNATATIVVDYQ 152
 
Name Accession Description Interval E-value
PRK15205 PRK15205
long polar fimbrial protein LpfE; Provisional
 1-176 2.34e-97

long polar fimbrial protein LpfE; Provisional


Pssm-ID: 237923  Cd Length: 176  Bit Score: 279.04  E-value: 2.34e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833680    1 MKFKRLLHSGiASLSLVACGVNAATDLGPAGDIHFSITITTKACEMEKSDLEVDMGTMTLQKPAAVGTVLSKKDFTIELK 80
Cdd:PRK15205   1 MKNKRALLPL-ALLLLTASGMAAPTDLGPAGDIHFTITIKAKACELEKDSLEVDMGTMVLQKPVKVGTELNQKNFSIGLK 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833680   81 ECDGISKATVEMDSQSDSDDDSMFALEAGGATGVALKIEDDKGTQQVPKGSSGTPIEWAIDGE-TTSLHYQASYVVVNTQ 159
Cdd:PRK15205  80 DCDGISKASVTMDGSPDPDDPSLFALDAGGATGVALKIKTSKGTQQYPKSTDGTPVEWAINGDgTTQLNYIASYVPVNAD 159

                        170
                 ....*....|....*..
gi 15833680  160 ATGGTANALVNFSITYE 176
Cdd:PRK15205 160 ATVGTANATVNFSVTYE 176
FimA COG3539
Pilin (type 1 fimbrial protein) [Cell motility];
11-176 1.42e-29

Pilin (type 1 fimbrial protein) [Cell motility];


Pssm-ID: 442760 [Multi-domain]  Cd Length: 172  Bit Score: 106.66  E-value: 1.42e-29
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833680  11 IASLSLVACGVNAATDLGPAGDIHFSITITTKACE--MEKSDLEVDMGTMTLQKPAAVGTVLSKKDFTIELKECDGISKA 88
Cdd:COG3539   4 LLLALLLALALSAAAAAAADGTVNFTGTVVAPTCTinTGSKDQTVDLGTVSTSDLNGVGSTSGPKPFSIKLTNCDAGTSN 83

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833680  89 TVEM--DSQSDSDDDSMFAL-EAGGATGVALKIEDDKGTqQVPKGSSGTPIEWAIDGETTsLHYQASYVVVNTQATGGTA 165
Cdd:COG3539  84 SVKVtfTGTADSANPGLLANtGSGGASGVGIQLLDSDGT-PIPLGTPSSAVTLTSNGSAT-LPFYARYVATGATVTAGSF 161

                       170
                ....*....|.
gi 15833680 166 NALVNFSITYE 176
Cdd:COG3539 162 NATATFTIDYQ 172
PRK15194 PRK15194
type 1 fimbrial protein subunit FimA;
1-176 1.26e-14

type 1 fimbrial protein subunit FimA;


Pssm-ID: 237920  Cd Length: 185  Bit Score: 68.06  E-value: 1.26e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833680    1 MKFKrLLHSGIASLSLVACGVNAAtDLGP----AGDIHFSITITTKACEM--EKSDLEVDMGTMTLQKPAAVGTVLSKKD 74
Cdd:PRK15194   1 MKLR-FISSAIASLLFVAGAAYAA-DPTPvsvdGGTIHFEGELVNAACSVntDSADQTVTLGQYRTAIFTAVGNTTALIP 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833680   75 FTIELKECDGISKAT--VEMDSQSDSDDDSMFALEAGG----ATGVALKIEDDKGTQQVPKGSSGTPIEWAIDGeTTSLH 148
Cdd:PRK15194  79 FTIQLNDCDPVVAATaaVAFSGQADATNDNLLAVASSTntttATGVGIEILDNTSSILKPDGATFSANQNLIEG-TNTLH 157

                        170       180
                 ....*....|....*....|....*...
gi 15833680  149 YQASYVVVNTQATGGTANALVNFSITYE 176
Cdd:PRK15194 158 FSARYKATGTSASAGQANADATFIMKYE 185
Fimbrial pfam00419
Fimbrial protein;
33-176 3.82e-10

Fimbrial protein;


Pssm-ID: 425671  Cd Length: 152  Bit Score: 55.52  E-value: 3.82e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833680    33 IHFSITITTK--ACEMEKSD-LEVDMGTMTLQKPAAVGTVLSKKDFTIELkECDGIS---KATVEMDSQSDSDDDSMFAL 106
Cdd:pfam00419   1 INFTGTVTRVpaTCKITAGTpIEVDFGQIPVNELNAGGEGSRQKPFSITL-ECSSGSsavKVTVGLFGTADASSPNLLLT 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15833680   107 --EAGGATGVALKIEDDKGTqQVPKGSSGTPIEWAID-GETTSLHYQASYVVVNTQA-TGGTANALVNFSITYE 176
Cdd:pfam00419  80 gnGAGAATGVGIRLYDANGG-ALPPNNGTSSIPVSATaAVATGITFTASLVATTGGTpTAGDFNATATIVVDYQ 152
PRK15209 PRK15209
long polar fimbrial protein LpfA; Provisional
 11-176 1.35e-08

long polar fimbrial protein LpfA; Provisional


Pssm-ID: 185131 [Multi-domain]  Cd Length: 174  Bit Score: 51.51  E-value: 1.35e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833680   11 IASLSLVACGVNAAtDLGPaGDIHFSITITTKAC--EMEKSDLEVDMGTMTLQKPAAVGTVLSKKDFTIELKECD--GIS 86
Cdd:PRK15209   8 LSALALTSTSVFAA-ESGD-GTVKFTGEIVDAPCvvSTDSQNQEVVLGQVKKSVFKAIGDKSSAKPFQIKLEDCDitTNK 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833680   87 KATVEMDSQSDSDDDSMFAL--EAGGATGVALKIEDDKGTQ-QVPKGSSGTPIEwaiDGETTsLHYQASYVVVNTQATGG 163
Cdd:PRK15209  86 KVNVSFNGVGDADDSTLVSVstEAGAATGVGIGIYDNANTLvELNTGKSTTTLA---AGQTV-LYFTANYVSTKDTVTTG 161

                        170
                 ....*....|...
gi 15833680  164 TANALVNFSITYE 176
Cdd:PRK15209 162 YGNAEVDFNLSYE 174
lpfA PRK15289
fimbrial protein; Provisional
 6-176 6.03e-07

fimbrial protein; Provisional


Pssm-ID: 185189  Cd Length: 190  Bit Score: 47.26  E-value: 6.03e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833680    6 LLHSGIASLSLVACGVNAATDlgpaGDIHFSITITTKACEM--EKSDLEVDMGTMTLQKPAAVGTVLSKKDFTIELKEC- 82
Cdd:PRK15289   5 IIGGAFTLASLMLAGHALAED----GVVHFVGEIVDTTCEVtsDTADQIVPLGKVSKNAFSGVGSLASPQKFSIKLENCp 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833680   83 DGISKATVEMDSQSDSDDDSMFAL----------------EAGGATGVALKIEDDKGTQQVP--KGSSGTPIEWAidgET 144
Cdd:PRK15289  81 ATYTQAAVRFDGTEAPGGDGDLKVgtpltagnpgdftgtgQAIAATGVGIRIFNQSDNSQVKlyNDSAYTAIDAE---GK 157

                        170       180       190
                 ....*....|....*....|....*....|..
gi 15833680  145 TSLHYQASYVVVNTQATGGTANALVNFSITYE 176
Cdd:PRK15289 158 AEMKFIARYVATNATVTAGTANADSQFTVEYK 189
PRK15190 PRK15190
fimbrial protein BcfE; Provisional
 8-176 3.44e-06

fimbrial protein BcfE; Provisional


Pssm-ID: 185112  Cd Length: 181  Bit Score: 45.07  E-value: 3.44e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833680    8 HSGIASLSLVACG-VNAATDlGPAGDIHFSITITTKACEMEKSDLE--VDMGTMTLQKPAAVGTVLSKKDFTIELKECD- 83
Cdd:PRK15190   5 HCALFAMGLMLCPqINASAD-DLAYNLEFTGTIVAQTCDIDISSLSqsIDLGQFAVGDFPSTGTTTKFKPFNINLKNCSr 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833680   84 GISKATVEMDSQSDSDDDSMFALEAGG-------ATGVALKI-EDDKGTQQVPKGSSgtpIEWAIDGETTSLHYQASYVV 155
Cdd:PRK15190  84 GIAGAKIWFTGEPDPDNPALLAITDTGmgsgnmlASGVGVEIlNDDQDTISINNADS---VVYPLKAGRNTLSFYIRYKS 160

                        170       180
                 ....*....|....*....|.
gi 15833680  156 VNTQATGGTANALVNFSITYE 176
Cdd:PRK15190 161 TRPTVTSGNATAVMYFDMQYE 181
PRK15191 PRK15191
fimbrial protein BcfF; Provisional
 31-176 2.84e-04

fimbrial protein BcfF; Provisional


Pssm-ID: 185113 [Multi-domain]  Cd Length: 172  Bit Score: 39.70  E-value: 2.84e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833680   31 GDIHFSITITTKACEM--EKSDLEVDMGTMTLQKPAAVGTVLSKKDFTIELKECDGI-SKATVEMDSQSDSDDDSMFALE 107
Cdd:PRK15191  23 GRVYVSGTITDNTCSLspGSENINVAMGAVSQRQFYRAGDGSAWQPFAIDLQNCGSTaSGVTVSFSGAADSRNTDLLALT 102

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15833680  108 AG--GATGVALKIEDDKGTQqVPKGSSGTPIEWAIDGETTSLHYQASYVVVNTQATGGTANALVNFSITYE 176
Cdd:PRK15191 103 AGesDASGIGIALYDQNKTL-IPLGQESDVVTLSPGQASAHLQFYARYLADGGAVTPGDANASATFILAYE 172
PRK15300 PRK15300
fimbrial protein StiA; Provisional
 4-175 1.10e-03

fimbrial protein StiA; Provisional


Pssm-ID: 185200  Cd Length: 179  Bit Score: 38.15  E-value: 1.10e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833680    4 KRLLHSGIASLSLVACGVNAATDLGPAGDIHFSITITTKACEMEKSDLEVDMGTMTLQKPAAVGTVLSKKDFTIELKECD 83
Cdd:PRK15300   2 KLSLKTLTVALAAITLSPAALADTAKDGTVHITGLIKQNACTVKTDSVEVTLQEEFASLFTAAGQTAGDTDFTIELENCD 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833680   84 GISKATVEMDSQSDSDDDSMFALE-AGGATGVALKIEDDKGT----QQVPKGSSGTPIEWAIDGETTSLHYQASYVVVNT 158
Cdd:PRK15300  82 ANVYSSVQARFEGTLDGTDATILKnEDDAENIGVQILDKTSTpmtfNDLQAWSAAVALPTAEGVTELSMPFTARYIATAV 161

                        170
                 ....*....|....*..
gi 15833680  159 QATGGTANALVNFSITY 175
Cdd:PRK15300 162 PVKSGTVDATATFYLQY 178
PRK15200 PRK15200
type 1 fimbrial protein subunit FimI;
16-175 1.21e-03

type 1 fimbrial protein subunit FimI;


Pssm-ID: 185122  Cd Length: 177  Bit Score: 37.91  E-value: 1.21e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833680   16 LVACGVNAATDLGPAGDIHFSITITTKACEM--EKSDLEVDMG---TMTLQKPAAVGTVlsKKDFTIELKECDGISKATV 90
Cdd:PRK15200  12 VLMSPVIAQPVMVESGRVHLRGQLVNGGCAVatESQDLRVLMGqyrTNAFTGPGSFAPV--SVPFSLRLISCSAEVWRHV 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833680   91 EMDSQSDSDDDS----MFALEAGGATGVALKIEDDKGTQQVPkgsSGTPIEWA-IDGETTSLHYQASYVVVNTQATGGTA 165
Cdd:PRK15200  90 GIAFAGVTPAEDphvfLASGEGIGNAGIGLALFDDQQRQIIP---NTLPLHYApILTSEMTLHFTARYRAISENMTPGRI 166

                        170
                 ....*....|
gi 15833680  166 NALVNFSITY 175
Cdd:PRK15200 167 HSEVWFTLVY 176
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH