|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
4-458 |
0e+00 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 828.66 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 4 MQRSKDSLAKWLSAILPVVIVGLVGLFAVTVIRDYGRETAAARQTLLEKGSVLIRALESGSRVGMGMRMHHAQQQALLEE 83
Cdd:PRK10364 1 MQRSKDSLAKWLSALLPVVIVGLVGLFSVTVIRDYGRETAAARQTLLEKGSVLIRALESGSRVGMGMRMHHAQQQALLEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 84 MAGQPGVRWFAVTDEQGTIVMHSNSGMVGKQLYSPQEMQQLHPGDEEVWRRIDSADGEPVLEIYRQFQPMFAAGMHRMRH 163
Cdd:PRK10364 81 MAGQPGVRWFAVTDEQGTIVAHSNPGMVGKQLYSPQEMQQLHPGDEEAWRRIDSADGEPVLEIYRQFQPMFAAGMHGMRH 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 164 MQQY--AATPQAIFIAFDASNIVSAEDREQRNTLIILFALATVLLASVLSFFWYRRYLRSRQLLQDEMKRKEKLVALGHL 241
Cdd:PRK10364 161 MQQYaaANTPQAIFIAFDASNLVSAQAREQRNTLIILFALATVLLASLLAFFWYRRYLRSRQLLQDEMKRKEKLVALGHL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 242 AAGVAHEIRNPLSSIKGLAKYFAERAPAGGEAHQLAQVMAKEADRLNRVVSELLELVKPTHLALQAVDLNTLINHSLQLV 321
Cdd:PRK10364 241 AAGVAHEIRNPLSSIKGLAKYFAERAPAGGEAHQLAQVMAKEADRLNRVVSELLELVKPTHLALQAVDLNDLINHSLQLV 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 322 SQDANCREIQLRFTANDTLPEIQADPDRLTQVLLNLYLNAIQAIGQHGVISVTASESGAGVKISVTDSGKGIAADQLEAI 401
Cdd:PRK10364 321 SQDANSREIQLRFTANDTLPEIQADPDRLTQVLLNLYLNAIQAIGQHGVISVTASESGAGVKISVTDSGKGIAADQLEAI 400
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*..
gi 15834180 402 FTPYFTTKAEGTGLGLAVVHNIVEQHGGTIQVASLEGKGARFTLWLPVNITRKDPQG 458
Cdd:PRK10364 401 FTPYFTTKAEGTGLGLAVVHNIVEQHGGTIQVASQEGKGATFTLWLPVNITRRDPQG 457
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
222-450 |
3.18e-85 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 265.56 E-value: 3.18e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 222 RQLLQDEMKRKEKLVALGHLAAGVAHEIRNPLSSIKGLAKYFAERAPAGgEAHQLAQVMAKEADRLNRVVSELLELVKPT 301
Cdd:COG3852 119 RKRLERELRRAEKLAAVGELAAGLAHEIRNPLTGIRGAAQLLERELPDD-ELREYTQLIIEEADRLNNLVDRLLSFSRPR 197
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 302 HLALQAVDLNTLINHSLQLVSQDANcREIQLRFTANDTLPEIQADPDRLTQVLLNLYLNAIQAIGQHGVISVTAS----- 376
Cdd:COG3852 198 PPEREPVNLHEVLERVLELLRAEAP-KNIRIVRDYDPSLPEVLGDPDQLIQVLLNLVRNAAEAMPEGGTITIRTRverqv 276
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15834180 377 -----ESGAGVKISVTDSGKGIAADQLEAIFTPYFTTKAEGTGLGLAVVHNIVEQHGGTIQVASLEGKGARFTLWLPVN 450
Cdd:COG3852 277 tlgglRPRLYVRIEVIDNGPGIPEEILDRIFEPFFTTKEKGTGLGLAIVQKIVEQHGGTIEVESEPGKGTTFRIYLPLE 355
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
124-449 |
2.27e-80 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 253.18 E-value: 2.27e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 124 LHPGDEEVWRRIDSADGEPVLEIYRQFQPMFAAGMHRMRHMQQYAATPQAIFIAFDASNIVSAEDREQRNTLIILFALAT 203
Cdd:COG4191 38 LLLALLLALLALLLLLLLLLLLLLLELLLLLLALLGGLLRLLLLLGLLLLLLLEALLLLLLAALDAEENAELEELERDIT 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 204 VLlasvlsffwyRRYLRSRQLLQDEMKRKEKLVALGHLAAGVAHEIRNPLSSIKG---LAKYFAERAPAGGEAHQLAQVM 280
Cdd:COG4191 118 EL----------ERAEEELRELQEQLVQSEKLAALGELAAGIAHEINNPLAAILGnaeLLRRRLEDEPDPEELREALERI 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 281 AKEADRLNRVVSELLELVKPTHLALQAVDLNTLINHSLQLVSQDANCREIQLRFTANDTLPEIQADPDRLTQVLLNLYLN 360
Cdd:COG4191 188 LEGAERAAEIVRSLRAFSRRDEEEREPVDLNELIDEALELLRPRLKARGIEVELDLPPDLPPVLGDPGQLEQVLLNLLIN 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 361 AIQAI--GQHGVISVTASESGAGVKISVTDSGKGIAADQLEAIFTPYFTTKA--EGTGLGLAVVHNIVEQHGGTIQVASL 436
Cdd:COG4191 268 AIDAMeeGEGGRITISTRREGDYVVISVRDNGPGIPPEVLERIFEPFFTTKPvgKGTGLGLSISYGIVEKHGGRIEVESE 347
|
330
....*....|...
gi 15834180 437 EGKGARFTLWLPV 449
Cdd:COG4191 348 PGGGTTFTITLPL 360
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
224-449 |
3.33e-79 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 252.19 E-value: 3.33e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 224 LLQD--EMKRKEKLVALGHLAAGVAHEIRNPLSSIKGLAKYFAERAPAGGEA-----HQLAQVMAKEADRLNRVVSELLE 296
Cdd:COG5000 185 VFDDitELLRAERLAAWGELARRIAHEIKNPLTPIQLSAERLRRKLADKLEEdredlERALDTIIRQVDRLKRIVDEFLD 264
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 297 LVKPTHLALQAVDLNTLINHSLQLVSQDANCREIQLRFTANDTLPEIQADPDRLTQVLLNLYLNAIQAIGQHGVISVTAS 376
Cdd:COG5000 265 FARLPEPQLEPVDLNELLREVLALYEPALKEKDIRLELDLDPDLPEVLADRDQLEQVLINLLKNAIEAIEEGGEIEVSTR 344
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15834180 377 ESGAGVKISVTDSGKGIAADQLEAIFTPYFTTKAEGTGLGLAVVHNIVEQHGGTIQVASLEGKGARFTLWLPV 449
Cdd:COG5000 345 REDGRVRIEVSDNGPGIPEEVLERIFEPFFTTKPKGTGLGLAIVKKIVEEHGGTIELESRPGGGTTFTIRLPL 417
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
220-451 |
1.91e-72 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 239.48 E-value: 1.91e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 220 RSRqlLQDEMKRKEKLVALGHLAAGVAHEIRNPLSSIKGLAKYFAERAPAGGEAHQLAqVMAKEADRLNRVVSELLELVK 299
Cdd:PRK11360 374 RKR--LQRRVARQERLAALGELVAGVAHEIRNPLTAIRGYVQIWRQQTSDPPSQEYLS-VVLREVDRLNKVIDQLLEFSR 450
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 300 PTHLALQAVDLNTLINHSLQLVSQDANCREIQLRFTANDTLPEIQADPDRLTQVLLNLYLNAIQAIGQHGVISVTASESG 379
Cdd:PRK11360 451 PRESQWQPVSLNALVEEVLQLFQTAGVQARVDFETELDNELPPIWADPELLKQVLLNILINAVQAISARGKIRIRTWQYS 530
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15834180 380 AG-VKISVTDSGKGIAADQLEAIFTPYFTTKAEGTGLGLAVVHNIVEQHGGTIQVASLEGKGARFTLWLPVNI 451
Cdd:PRK11360 531 DGqVAVSIEDNGCGIDPELLKKIFDPFFTTKAKGTGLGLALSQRIINAHGGDIEVESEPGVGTTFTLYLPINP 603
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
225-449 |
1.71e-67 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 223.70 E-value: 1.71e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 225 LQDEMKRKEKLVALGHLAAGVAHEIRNPLSSIKGLAKYFAERApagGEAHQL-AQVMAKEADRLNRVVSELLELVKPTHL 303
Cdd:COG5809 257 LEELLRKSEKLSVVGELAAGIAHEIRNPLTSLKGFIQLLKDTI---DEEQKTyLDIMLSELDRIESIISEFLVLAKPQAI 333
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 304 ALQAVDLNTLINHSLQLVSQDANCREIQLRFTANDTLPEIQADPDRLTQVLLNLYLNAIQAIGQHGVISV-TASESGAGV 382
Cdd:COG5809 334 KYEPKDLNTLIEEVIPLLQPQALLKNVQIELELEDDIPDILGDENQLKQVFINLLKNAIEAMPEGGNITIeTKAEDDDKV 413
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15834180 383 KISVTDSGKGIAADQLEAIFTPYFTTKAEGTGLGLAVVHNIVEQHGGTIQVASLEGKGARFTLWLPV 449
Cdd:COG5809 414 VISVTDEGCGIPEERLKKLGEPFYTTKEKGTGLGLMVSYKIIEEHGGKITVESEVGKGTTFSITLPI 480
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
143-450 |
1.29e-66 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 216.31 E-value: 1.29e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 143 VLEIYRQFQPMFAAGMHRMRHMQQYAATPQAIFIAFDASNIVSAEDREQRNTLIILFALATVLLASVLSFFWYRRYLRSR 222
Cdd:COG0642 15 LLLLLLALLLLLLLLLLLALLLLLALLLLLLLLLLLLLLLALALLALLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 223 QLLQDEMKRKEKLVALGHLAAGVAHEIRNPLSSIKGLAKYFAERAPAggEAHQLAQVMAKEADRLNRVVSELLELVK--- 299
Cdd:COG0642 95 LLLALLLLLEEANEAKSRFLANVSHELRTPLTAIRGYLELLLEELDE--EQREYLETILRSADRLLRLINDLLDLSRlea 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 300 -PTHLALQAVDLNTLINHSLQLVSQDANCREIQLRFTANDTLPEIQADPDRLTQVLLNLYLNAIQAIGQHGVISVTASES 378
Cdd:COG0642 173 gKLELEPEPVDLAELLEEVVELFRPLAEEKGIELELDLPDDLPTVRGDPDRLRQVLLNLLSNAIKYTPEGGTVTVSVRRE 252
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15834180 379 GAGVKISVTDSGKGIAADQLEAIFTPYFTTKA----EGTGLGLAVVHNIVEQHGGTIQVASLEGKGARFTLWLPVN 450
Cdd:COG0642 253 GDRVRISVEDTGPGIPPEDLERIFEPFFRTDPsrrgGGTGLGLAIVKRIVELHGGTIEVESEPGKGTTFTVTLPLA 328
|
|
| KinC |
COG5807 |
Sporulation sensor histidine kinase C [Cell cycle control, cell division, chromosome ... |
217-449 |
2.77e-64 |
|
Sporulation sensor histidine kinase C [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444509 [Multi-domain] Cd Length: 358 Bit Score: 211.18 E-value: 2.77e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 217 RYLRSRQLLQDEMKRKEKLVALGHLAAGVAHEIRNPLSSIKGLAKYFAERAPaGGEAHQLAQVMAKEADRLNRVVSELLE 296
Cdd:COG5807 126 RDITKRKEAEDKLLRSEKLSVAGELAAGIAHEIRNPLTSIKGFLQLLQESRE-DSEREEYFNIIISEIDRINTIITELLV 204
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 297 LVKPTHLALQAVDLNTLINHSLQLVSQDANCREIQLRFTANDTLPEIQADPDRLTQVLLNLYLNAIQAIGQHGVISVTAS 376
Cdd:COG5807 205 LSKPKKFNFKKLNLNDVLEDVIALLSTEAILKNISIKYDLADDEPVINGDKNQLKQVFINLIKNAIEAMETGGNITIKTY 284
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15834180 377 ESGAGVKISVTDSGKGIAADQLEAIFTPYFTTKAEGTGLGLAVVHNIVEQHGGTIQVASLEGKGARFTLWLPV 449
Cdd:COG5807 285 VEGDFVVISVKDEGIGIPEEVLEKIGEPFFTTKEEGTGLGLSICKKIIEEHNGTIEVESKPGKGTTFTIYLPL 357
|
|
| KinB |
COG5806 |
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome ... |
194-449 |
4.40e-62 |
|
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444508 [Multi-domain] Cd Length: 412 Bit Score: 207.03 E-value: 4.40e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 194 TLIILFALATVLLASVLSFfwyrryLRSRQLLQDEMKRKEKLVALGHLAAGVAHEIRNPLSSIKGLAKYFAERAPAGGEA 273
Cdd:COG5806 163 YFIIIQLLAMLIAVYLIEN------LIENILLRKELQRAEKLEVVSELAASIAHEVRNPLTVVRGFIQLLQEPELSDEKR 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 274 HQLAQVMAKEADRLNRVVSELLELVKPTHLALQAVDLNTLINHSLQLVSQDANCREIQLRFTANDTLpEIQADPDRLTQV 353
Cdd:COG5806 237 KQYIRIALEELDRAEAIITDYLTFAKPQPEKLEKIDVSEELEHVIDVLSPYANMNNVEIQTELEPGL-YIEGDRQKLQQC 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 354 LLNLYLNAIQAIGQHGVISVTASESGAGVKISVTDSGKGIAADQLEAIFTPYFTTKAEGTGLGLAVVHNIVEQHGGTIQV 433
Cdd:COG5806 316 LINIIKNGIEAMPNGGTLTIDVSIDKNKVIISIKDTGVGMTKEQLERLGEPYFSTKEKGTGLGTMVSYRIIEAMNGTIRV 395
|
250
....*....|....*.
gi 15834180 434 ASLEGKGARFTLWLPV 449
Cdd:COG5806 396 ESEVGKGTTFTITLPL 411
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
93-449 |
8.35e-62 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 208.82 E-value: 8.35e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 93 FAVTDEQGTIVMHSNSG----------MVGKQLYspqemQQLHPGD-EEVWRRIDSadgepvleIYRQFQPMfaagmhrm 161
Cdd:COG5805 170 ICVIDTDGRILFINESIerlfgapreeLIGKNLL-----ELLHPCDkEEFKERIES--------ITEVWQEF-------- 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 162 rHMQQYAATPQAIFIAFDASnIVSAEDREQrntliilfalatvllaSVLSFFWYRRYLRSRQLLQDEMKRKEKLVALGHL 241
Cdd:COG5805 229 -IIEREIITKDGRIRYFEAV-IVPLIDTDG----------------SVKGILVILRDITEKKEAEELMARSEKLSIAGQL 290
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 242 AAGVAHEIRNPLSSIKGlakyFAERAPAGGEA-HQLAQVMAKEADRLNRVVSELLELVKPTHLALQAVDLNTLINHSLQL 320
Cdd:COG5805 291 AAGIAHEIRNPLTSIKG----FLQLLQPGIEDkEEYFDIMLSELDRIESIISEFLALAKPQAVNKEKENINELIQDVVTL 366
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 321 VSQDANCREIQLRFTANDTLPEIQADPDRLTQVLLNLYLNAIQAIGQHGVISVTASESGAGVKISVTDSGKGIAADQLEA 400
Cdd:COG5805 367 LETEAILHNIQIRLELLDEDPFIYCDENQIKQVFINLIKNAIEAMPNGGTITIHTEEEDNSVIIRVIDEGIGIPEERLKK 446
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 15834180 401 IFTPYFTTKAEGTGLGLAVVHNIVEQHGGTIQVASLEGKGARFTLWLPV 449
Cdd:COG5805 447 LGEPFFTTKEKGTGLGLMVSYKIIENHNGTIDIDSKVGKGTTFTITLPL 495
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
114-450 |
9.90e-62 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 205.56 E-value: 9.90e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 114 QLYSPQEMQQLHPGDEEVWRRIDSADGEPVLEIYRQFQPMFAAGMHRMRHMQQYAATPQAIFIAFDASNIVSAEDREQRN 193
Cdd:COG5002 43 LLLLLLLLLLALLLLLLLLLLLLLALLLLLLLLLLLLALALLLLALLLLLLLLLLLLALLILLLLLALLILLAALLLLLS 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 194 TLIILFALATVLLASVLSFFWYRRYLRSRQLLQDEMKRKEKLvaLGHLAAGVAHEIRNPLSSIKGLAKYFAERAPAGGEA 273
Cdd:COG5002 123 ELLLLLLLLGRLSLRLSALLLGLLLLAAVERDITELERLEQM--RREFVANVSHELRTPLTSIRGYLELLLDGAADDPEE 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 274 HQ-LAQVMAKEADRLNRVVSELLELVK----PTHLALQAVDLNTLINHSLQLVSQDANCREIQLRFTANDTLPEIQADPD 348
Cdd:COG5002 201 RReYLEIILEEAERLSRLVNDLLDLSRlesgELKLEKEPVDLAELLEEVVEELRPLAEEKGIELELDLPEDPLLVLGDPD 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 349 RLTQVLLNLYLNAIQAIGQHGVISVTASESGAGVKISVTDSGKGIAADQLEAIFTPYFTT------KAEGTGLGLAVVHN 422
Cdd:COG5002 281 RLEQVLTNLLDNAIKYTPEGGTITVSLREEDDQVRISVRDTGIGIPEEDLPRIFERFYRVdksrsrETGGTGLGLAIVKH 360
|
330 340
....*....|....*....|....*...
gi 15834180 423 IVEQHGGTIQVASLEGKGARFTLWLPVN 450
Cdd:COG5002 361 IVEAHGGRIWVESEPGKGTTFTITLPLA 388
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
225-449 |
2.69e-61 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 199.75 E-value: 2.69e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 225 LQDEMKRKEKLVAL-GHLAAGVAHEIRNPLSSIKGLAKYFAERAPAGGEAHQ-LAQVMAKEADRLNRVVSELLELVK--- 299
Cdd:COG2205 2 LEEALEELEELERLkSEFLANVSHELRTPLTSILGAAELLLDEEDLSPEERReLLEIIRESAERLLRLIEDLLDLSRles 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 300 -PTHLALQAVDLNTLINHSLQLVSQDANCREIQLRFTANDTLPEIQADPDRLTQVLLNLYLNAIQAIGQHGVISVTASES 378
Cdd:COG2205 82 gKLSLELEPVDLAELLEEAVEELRPLAEEKGIRLELDLPPELPLVYADPELLEQVLANLLDNAIKYSPPGGTITISARRE 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15834180 379 GAGVKISVTDSGKGIAADQLEAIFTPYF----TTKAEGTGLGLAVVHNIVEQHGGTIQVASLEGKGARFTLWLPV 449
Cdd:COG2205 162 GDGVRISVSDNGPGIPEEELERIFERFYrgdnSRGEGGTGLGLAIVKRIVEAHGGTIWVESEPGGGTTFTVTLPL 236
|
|
| KinD |
COG5808 |
Sporulation sensor histidine kinase D [Cell cycle control, cell division, chromosome ... |
128-449 |
1.96e-58 |
|
Sporulation sensor histidine kinase D [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444510 [Multi-domain] Cd Length: 454 Bit Score: 198.82 E-value: 1.96e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 128 DEEVWR-RIDSADGEPVLEIYRQFQPMFAAGMHRmrHMQQYAATPQAIFIAFDASNIVSAEDREQRNTLIILFALATVLL 206
Cdd:COG5808 131 RMDYIRaLINILDPDKYIEIVDQNGQSVFTSGHR--EESKSVSNKLDKVPWEVEVYPNPVTNDELGQALAIRKLIILVLI 208
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 207 ASVLSFFWYRRYLRSRQL---LQDEMKRKEKLValGHLAAGVAHEIRNPLSSIKGLAKYFAERAPaGGEAHQLAQVMAKE 283
Cdd:COG5808 209 SIIFLLLQYNLLKRKTLLervIQEINTQKLELI--GTFAASTAHEIRNPLTSIKGFIQLLQEKYP-ELEDQKYFDIIQEE 285
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 284 ADRLNRVVSELLELVKPTHLALQAVDLNTLINHSLQLVSQDANCREIQLRFTANDTLPEIQADPDRLTQVLLNLYLNAIQ 363
Cdd:COG5808 286 IQRINQIVSEFLVLGKPTAKKLELDDLNELIEEILSIIDSEANLKNIRVEKQSLDEPLHIKCDKDRIKQVLLNLIKNAIE 365
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 364 AIGQHGVISVTASESGAGVKISVTDSGKGIAADQLEAIFTPYFTTKAEGTGLGLAVVHNIVEQHGGTIQVASLEGKGARF 443
Cdd:COG5808 366 AMKEGGKLTISIENDDEKAVIEVIDNGEGIPEDIIDEIFEPFVTTKEGGTGLGLSVCKRIVEMHGGEIDIESEEGKGTTF 445
|
....*.
gi 15834180 444 TLWLPV 449
Cdd:COG5808 446 TIRLPL 451
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
11-452 |
1.17e-42 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 157.64 E-value: 1.17e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 11 LAKWLSAILPVVIVGLVGLFAVTVIRDYGRETAAARQTLLEKGSVLIRALESGSRVGMGMRMHHAQQQALLEEMAGQPGV 90
Cdd:COG4251 66 LLLLLLLLVLAALALLLLLLLLELALVLLALLLVLLLLLALLLLLALLLLLELLLLLLALLLLLLLLALLLLEELALLRL 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 91 RWFAVTDEQGTIVMHSNSGMVGKQLYSPQEMQQLHPGDEEVWRRIDSADGEPVLEIYRQFQPMFAAGMHRMRHMQQYAAT 170
Cdd:COG4251 146 ALALLLLLLLLLLLLLLLLALILALLLAALAELELLLLLLLVLLLLLLLLLLLLLLLLRLLLELLLLLEAELLLSLGGGL 225
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 171 PQAIFIAFDASNIVSAEDREQRNTLIILFALATVLLasvlsffwyRRYLRSRQLLQDEMKRKEKlvALGHLAAGVAHEIR 250
Cdd:COG4251 226 GLLLLLLLLLVLLLLLILLLLLLILVLELLELRLEL---------EELEEELEERTAELERSNE--ELEQFAYVASHDLR 294
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 251 NPLSSIKGLAKYFAERAPA--GGEAHQLAQVMAKEADRLNRVVSELLEL--VKPTHLALQAVDLNTLINHSLQLVSQDAN 326
Cdd:COG4251 295 EPLRKISGFSQLLEEDYGDklDEEGREYLERIRDAAERMQALIDDLLAYsrVGRQELEFEPVDLNELLEEVLEDLEPRIE 374
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 327 CREIQLRFtanDTLPEIQADPDRLTQVLLNLYLNAI--QAIGQHGVISVTASESGAGVKISVTDSGKGIAADQLEAIFTP 404
Cdd:COG4251 375 ERGAEIEV---GPLPTVRGDPTLLRQVFQNLISNAIkySRPGEPPRIEIGAEREGGEWVFSVRDNGIGIDPEYAEKIFEI 451
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|..
gi 15834180 405 YFT----TKAEGTGLGLAVVHNIVEQHGGTIQVASLEGKGARFTLWLPVNIT 452
Cdd:COG4251 452 FQRlhsrDEYEGTGIGLAIVKKIVERHGGRIWVESEPGEGATFYFTLPKAPA 503
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
216-449 |
4.51e-38 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 147.52 E-value: 4.51e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 216 RRYLRS-RQLLQDEMKRKEKLVALGHLAAGVAHEIRNPLSSIKGLAKYFAERAPAGGEAHQLAQVMAKEADRLNRVVSEL 294
Cdd:PRK13837 427 RRRLETeRDALERRLEHARRLEAVGTLASGIAHNFNNILGAILGYAEMALNKLARHSRAARYIDEIISAGARARLIIDQI 506
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 295 LELVKPTHLALQAVDLNTLINHSLQL--VSQDANCrEIQLRFTANDTLpeIQADPDRLTQVLLNLYLNAIQAIGQHGVIS 372
Cdd:PRK13837 507 LAFGRKGERNTKPFDLSELVTEIAPLlrVSLPPGV-ELDFDQDQEPAV--VEGNPAELQQVLMNLCSNAAQAMDGAGRVD 583
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 373 VTASES---------------GAGVKISVTDSGKGIAADQLEAIFTPYFTTKAEGTGLGLAVVHNIVEQHGGTIQVASLE 437
Cdd:PRK13837 584 ISLSRAklrapkvlshgvlppGRYVLLRVSDTGAGIDEAVLPHIFEPFFTTRAGGTGLGLATVHGIVSAHAGYIDVQSTV 663
|
250
....*....|..
gi 15834180 438 GKGARFTLWLPV 449
Cdd:PRK13837 664 GRGTRFDVYLPP 675
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
345-449 |
1.01e-36 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 130.46 E-value: 1.01e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 345 ADPDRLTQVLLNLYLNAIQAIGQHGVISVTASESGAGVKISVTDSGKGIAADQLEAIFTPYFTTKA-----EGTGLGLAV 419
Cdd:smart00387 1 GDPDRLRQVLSNLLDNAIKYTPEGGRITVTLERDGDHVEITVEDNGPGIPPEDLEKIFEPFFRTDKrsrkiGGTGLGLSI 80
|
90 100 110
....*....|....*....|....*....|
gi 15834180 420 VHNIVEQHGGTIQVASLEGKGARFTLWLPV 449
Cdd:smart00387 81 VKKLVELHGGEISVESEPGGGTTFTITLPL 110
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
347-449 |
1.08e-36 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 130.23 E-value: 1.08e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 347 PDRLTQVLLNLYLNAIQAIGQHGVISVTASESGAGVKISVTDSGKGIAADQLEAIFTPYFTTK--AEGTGLGLAVVHNIV 424
Cdd:cd16943 1 PSQLNQVLLNLLVNAAQAMEGRGRITIRTWAHVDQVLIEVEDTGSGIDPEILGRIFDPFFTTKpvGEGTGLGLSLSYRII 80
|
90 100
....*....|....*....|....*
gi 15834180 425 EQHGGTIQVASLEGKGARFTLWLPV 449
Cdd:cd16943 81 QKHGGTIRVASVPGGGTRFTIILPI 105
|
|
| HATPase |
cd00075 |
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ... |
350-447 |
6.47e-33 |
|
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ATPase (HATPase) domains of several ATP-binding proteins such as histidine kinase, DNA gyrase B, topoisomerases, heat shock protein 90 (HSP90), phytochrome-like ATPases and DNA mismatch repair proteins. Domains belonging to this superfamily are also referred to as GHKL (gyrase, heat-shock protein 90, histidine kinase, MutL) ATPase domains.
Pssm-ID: 340391 [Multi-domain] Cd Length: 102 Bit Score: 120.02 E-value: 6.47e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 350 LTQVLLNLYLNAIQAIGQHGVISVTASESGAGVKISVTDSGKGIAADQLEAIFTPYFTTK----AEGTGLGLAVVHNIVE 425
Cdd:cd00075 1 LEQVLSNLLDNALKYSPPGGTIEISLRQEGDGVVLEVEDNGPGIPEEDLERIFERFYRGDksreGGGTGLGLAIVRRIVE 80
|
90 100
....*....|....*....|..
gi 15834180 426 QHGGTIQVASLEGKGARFTLWL 447
Cdd:cd00075 81 AHGGRITVESEPGGGTTFTVTL 102
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
246-450 |
3.13e-32 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 126.50 E-value: 3.13e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 246 AHEIRNPLSSIKGLAKyfaerapaGGEAHQLAQVMAKEADRLNRVVSELLELVKPTHLAlqAVdLNTLINhslqlvsqDA 325
Cdd:COG3290 197 RHDFRNHLHTISGLLQ--------LGEYDEALEYIDEISEELQELIDSLLSRIGNPVLA--AL-LLGKAA--------RA 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 326 NCREIQLRFTANDTLPEIQADPDRLTQVLLNLYLNAIQAI----GQHGVISVTASESGAGVKISVTDSGKGIAADQLEAI 401
Cdd:COG3290 258 RERGIDLTIDIDSDLPDLPLSDTDLVTILGNLLDNAIEAVeklpEEERRVELSIRDDGDELVIEVEDSGPGIPEELLEKI 337
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 15834180 402 FTPYFTTKA-EGTGLGLAVVHNIVEQHGGTIQVASLEGKGARFTLWLPVN 450
Cdd:COG3290 338 FERGFSTKLgEGRGLGLALVKQIVEKYGGTIEVESEEGEGTVFTVRLPKE 387
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
345-451 |
1.07e-31 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 117.08 E-value: 1.07e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 345 ADPDRLTQVLLNLYLNAIQAIGQHGVISVTASEsGAGVKISVTDSGKGIAADQLEAIFTPYFT---TKAEGTGLGLAVVH 421
Cdd:pfam02518 1 GDELRLRQVLSNLLDNALKHAAKAGEITVTLSE-GGELTLTVEDNGIGIPPEDLPRIFEPFSTadkRGGGGTGLGLSIVR 79
|
90 100 110
....*....|....*....|....*....|
gi 15834180 422 NIVEQHGGTIQVASLEGKGARFTLWLPVNI 451
Cdd:pfam02518 80 KLVELLGGTITVESEPGGGTTVTLTLPLAQ 109
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
246-449 |
2.13e-28 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 116.87 E-value: 2.13e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 246 AHEIRNPLSSIKGLAKYFAERAPAGGEAHQLAQVMAkEADRLNRVVSELLELVK----PTHLALQAVDLNTLINHSLQLV 321
Cdd:PRK11100 264 THELKSPLAAIRGAAELLQEDPPPEDRARFTGNILT-QSARLQQLIDRLLELARleqrQELEVLEPVALAALLEELVEAR 342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 322 SQDANCREIQLRFTANDTlpEIQADPDRLTQVLLNLYLNAIQAIGQHGVISVTASESGAGVKISVTDSGKGIAADQLEAI 401
Cdd:PRK11100 343 EAQAAAKGITLRLRPDDA--RVLGDPFLLRQALGNLLDNAIDFSPEGGTITLSAEVDGEQVALSVEDQGPGIPDYALPRI 420
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 15834180 402 F-----TPYFTTKAEGTGLGLAVVHNIVEQHGGTIQVASLEGKGARFTLWLPV 449
Cdd:PRK11100 421 FerfysLPRPANGRKSTGLGLAFVREVARLHGGEVTLRNRPEGGVLATLTLPR 473
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
350-448 |
4.30e-27 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 104.40 E-value: 4.30e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 350 LTQVLLNLYLNAIQAIGQHGV------ISVTASESGAgVKISVTDSGKGIAADQLEAIFTPYFTTKAEGTGLGLAVVHNI 423
Cdd:cd16920 1 IQQVLINLVRNGIEAMSEGGCerreltIRTSPADDRA-VTISVKDTGPGIAEEVAGQLFDPFYTTKSEGLGMGLSICRSI 79
|
90 100
....*....|....*....|....*
gi 15834180 424 VEQHGGTIQVASLEGKGARFTLWLP 448
Cdd:cd16920 80 IEAHGGRLSVESPAGGGATFQFTLP 104
|
|
| glnL |
PRK11073 |
nitrogen regulation protein NR(II); |
222-449 |
8.26e-27 |
|
nitrogen regulation protein NR(II);
Pssm-ID: 182947 [Multi-domain] Cd Length: 348 Bit Score: 110.56 E-value: 8.26e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 222 RQLLQdEMKRKEKLVALGHLAAGVAHEIRNPLSSIKGLAKYFAERAPaGGEAHQLAQVMAKEADRLNRVVSELLelvKPT 301
Cdd:PRK11073 115 RRLSQ-EQLQHAQQVAARDLVRGLAHEIKNPLGGLRGAAQLLSKALP-DPALTEYTKVIIEQADRLRNLVDRLL---GPQ 189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 302 HLALQAVD-LNTLINHSLQLVSQDANcREIQLRFTANDTLPEIQADPDRLTQVLLNLYLNAIQAIGQ-HGVISV---TAS 376
Cdd:PRK11073 190 RPGTHVTEsIHKVAERVVQLVSLELP-DNVRLIRDYDPSLPELAHDPDQIEQVLLNIVRNALQALGPeGGTITLrtrTAF 268
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 377 ESGA-------GVKISVTDSGKGIAADQLEAIFTPYFTTKAEGTGLGLAVVHNIVEQHGGTIQVASLEGKgARFTLWLPV 449
Cdd:PRK11073 269 QLTLhgeryrlAARIDIEDNGPGIPPHLQDTLFYPMVSGREGGTGLGLSIARNLIDQHSGKIEFTSWPGH-TEFSVYLPI 347
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
225-449 |
2.03e-26 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 110.04 E-value: 2.03e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 225 LQDEMKRKEKLVALghlaagVAHEIRNPLS-------SIK-GLAKYFAERAPAGGEahQLAQVMAKEADRLNRVVSELLE 296
Cdd:PRK09303 144 LLEQLKFKDRVLAM------LAHDLRTPLTaaslaleTLElGQIDEDTELKPALIE--QLQDQARRQLEEIERLITDLLE 215
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 297 ---------LVKPTHLALQAVDLNTLINHSLQLVSqdancREIQLRFTANDTLPEIQADPDRLTQVLLNLYLNAIQAIGQ 367
Cdd:PRK09303 216 vgrtrwealRFNPQKLDLGSLCQEVILELEKRWLA-----KSLEIQTDIPSDLPSVYADQERIRQVLLNLLDNAIKYTPE 290
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 368 HGVISVTA-SESGAGVKISVTDSGKGIAADQLEAIFTPYFTTK----AEGTGLGLAVVHNIVEQHGGTIQVASLEGKGAR 442
Cdd:PRK09303 291 GGTITLSMlHRTTQKVQVSICDTGPGIPEEEQERIFEDRVRLPrdegTEGYGIGLSVCRRIVRVHYGQIWVDSEPGQGSC 370
|
....*..
gi 15834180 443 FTLWLPV 449
Cdd:PRK09303 371 FHFTLPV 377
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
350-447 |
1.05e-25 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 100.61 E-value: 1.05e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 350 LTQVLLNLYLNAIQAIG--QHGVISVTASESGAGVKISVTDSGKGIAADQLEAIFTPYFTTK--AEGTGLGLAVVHNIVE 425
Cdd:cd16976 1 IQQVLMNLLQNALDAMGkvENPRIRIAARRLGGRLVLVVRDNGPGIAEEHLSRVFDPFFTTKpvGKGTGLGLSISYGIVE 80
|
90 100
....*....|....*....|..
gi 15834180 426 QHGGTIQVASLEGKGARFTLWL 447
Cdd:cd16976 81 EHGGRLSVANEEGAGARFTFDL 102
|
|
| PRK13557 |
PRK13557 |
histidine kinase; Provisional |
222-449 |
5.10e-25 |
|
histidine kinase; Provisional
Pssm-ID: 237425 [Multi-domain] Cd Length: 540 Bit Score: 107.83 E-value: 5.10e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 222 RQLLQDEMKRKEKLVALGHLAAGVAHEIRNPLSSIKGLAKYF---AERAPAGGEAHQLAQVMAKEA-DRLNRVVSELLEL 297
Cdd:PRK13557 147 RRDAEDALRQAQKMEALGQLTGGIAHDFNNLLQVMSGYLDVIqaaLSHPDADRGRMARSVENIRAAaERAATLTQQLLAF 226
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 298 VKPTHLALQAVDLNTLINHSLQLVSQDANcREIQLRFTANDTLPEIQADPDRLTQVLLNLYLNAIQAIGQHGVISV-TAS 376
Cdd:PRK13557 227 ARKQRLEGRVLNLNGLVSGMGELAERTLG-DAVTIETDLAPDLWNCRIDPTQAEVALLNVLINARDAMPEGGRVTIrTRN 305
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 377 E--------------SGAGVKISVTDSGKGIAADQLEAIFTPYFTTKAE--GTGLGLAVVHNIVEQHGGTIQVASLEGKG 440
Cdd:PRK13557 306 VeiededlamyhglpPGRYVSIAVTDTGSGMPPEILARVMDPFFTTKEEgkGTGLGLSMVYGFAKQSGGAVRIYSEVGEG 385
|
....*....
gi 15834180 441 ARFTLWLPV 449
Cdd:PRK13557 386 TTVRLYFPA 394
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
226-441 |
8.50e-25 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 107.46 E-value: 8.50e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 226 QDEMKRKEKLVALGHLAAGVAHEIRNPLSSIKgLAKYFAERAPAGGEAHQLAQV---MAKEADRLNRVVSELLELVKPTH 302
Cdd:COG4192 421 QDELIQAAKMAVVGQTMTSLAHELNQPLNAMS-MYLFSAKKALEQENYAQLPTSldkIEGLIERMDKIIKSLRQFSRKSD 499
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 303 LALQAVDLNTLINHSLQLVSQDANCREIQLrftandTLPE---IQADPDRLTQVLLNLYLNAIQAIGQHGVISVTASESG 379
Cdd:COG4192 500 TPLQPVDLRQVIEQAWELVESRAKPQQITL------HIPDdlmVQGDQVLLEQVLVNLLVNALDAVATQPQISVDLLSNA 573
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15834180 380 AGVKISVTDSGKGIAAdqLEAIFTPYFTTKAEGTGLGLAVVHNIVEQHGGTIQVASLEGKGA 441
Cdd:COG4192 574 ENLRVAISDNGNGWPL--VDKLFTPFTTTKEVGLGLGLSICRSIMQQFGGDLYLASTLERGA 633
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
350-449 |
3.90e-23 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 93.71 E-value: 3.90e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 350 LTQVLLNLYLNAIQaIGQHGVISVTAS-----ESGAGVKISVTDSGKGIAADQLEAIFTPY------FTTKAEGTGLGLA 418
Cdd:cd16922 1 LRQILLNLLGNAIK-FTEEGEVTLRVSleeeeEDGVQLRFSVEDTGIGIPEEQQARLFEPFsqadssTTRKYGGTGLGLA 79
|
90 100 110
....*....|....*....|....*....|.
gi 15834180 419 VVHNIVEQHGGTIQVASLEGKGARFTLWLPV 449
Cdd:cd16922 80 ISKKLVELMGGDISVESEPGQGSTFTFTLPL 110
|
|
| cztS_silS_copS |
TIGR01386 |
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain ... |
238-448 |
3.95e-23 |
|
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.
Pssm-ID: 273593 [Multi-domain] Cd Length: 457 Bit Score: 101.31 E-value: 3.95e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 238 LGHLAAGVAHEIRNPLSSIKGLAKyFAERAPAGGEAHQ-LAQVMAKEADRLNRVVSELLELVKPTH----LALQAVDLNT 312
Cdd:TIGR01386 241 LSQFSADLAHELRTPLTNLLGQTQ-VALSQPRTGEEYReVLESNLEELERLSRMVSDMLFLARADNgqlaLERVRLDLAA 319
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 313 LINHSLQLVSQDANCREIQLRFTANDTLPeiqADPDRLTQVLLNLYLNAIQAIGQHGVISVTASESGAGVKISVTDSGKG 392
Cdd:TIGR01386 320 ELAKVAEYFEPLAEERGVRIRVEGEGLVR---GDPQMFRRAISNLLSNALRHTPDGGTITVRIERRSDEVRVSVSNPGPG 396
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15834180 393 IAADQLEAIFTPYF------TTKAEGTGLGLAVVHNIVEQHGGTIQVASLEGKgARFTLWLP 448
Cdd:TIGR01386 397 IPPEHLSRLFDRFYrvdparSNSGEGTGLGLAIVRSIMEAHGGRASAESPDGK-TRFILRFP 457
|
|
| PRK11091 |
PRK11091 |
aerobic respiration control sensor protein ArcB; Provisional |
245-457 |
8.08e-22 |
|
aerobic respiration control sensor protein ArcB; Provisional
Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 98.47 E-value: 8.08e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 245 VAHEIRNPLSSIKGLAKYFAErAPAGGEAHQLAQVMAKEADRLNRVVSELLELVK----PTHLALQAVD----LNTLINH 316
Cdd:PRK11091 290 ISHELRTPLNGIVGLSRILLD-TELTAEQRKYLKTIHVSAITLGNIFNDIIDMDKmerrKLQLDNQPIDftdfLADLENL 368
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 317 SLQLVSQdancREIQLRFTANDTLPE-IQADPDRLTQVLLNLYLNAIQaIGQHGVISVTAS-ESGAGVKISVTDSGKGIA 394
Cdd:PRK11091 369 SGLQAEQ----KGLRFDLEPLLPLPHkVITDGTRLRQILWNLISNAVK-FTQQGGVTVRVRyEEGDMLTFEVEDSGIGIP 443
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 395 ADQLEAIFTPYFTTK-------AEGTGLGLAVVHNIVEQHGGTIQVASLEGKGARFTLWLPVNITRKDPQ 457
Cdd:PRK11091 444 EDELDKIFAMYYQVKdshggkpATGTGIGLAVSKRLAQAMGGDITVTSEEGKGSCFTLTIHAPAVAEEVE 513
|
|
| HATPase_CckA-like |
cd16919 |
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar ... |
350-448 |
9.83e-22 |
|
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar to Brucella abortus 2308 CckA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) similar to Brucella abortus 2308 CckA, which is a component of an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival; phosphoryl transfer initiates from the sensor kinase CckA and proceeds via the ChpT phosphotransferase to two regulatory substrates: the DNA-binding response regulator CtrA and the phospho-receiver protein CpdR. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), a REC signal receiver domain, and some contain PAS or PAS and GAF sensor domain(s).
Pssm-ID: 340396 [Multi-domain] Cd Length: 116 Bit Score: 90.13 E-value: 9.83e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 350 LTQVLLNLYLNAIQAIGQHGVISVTASE---------------SGAGVKISVTDSGKGIAADQLEAIFTPYFTTKAEG-- 412
Cdd:cd16919 1 LELAILNLAVNARDAMPEGGRLTIETSNqrvdadyalnyrdliPGNYVCLEVSDTGSGMPAEVLRRAFEPFFTTKEVGkg 80
|
90 100 110
....*....|....*....|....*....|....*.
gi 15834180 413 TGLGLAVVHNIVEQHGGTIQVASLEGKGARFTLWLP 448
Cdd:cd16919 81 TGLGLSMVYGFVKQSGGHLRIYSEPGVGTTVRIYLP 116
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
243-457 |
3.46e-21 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 96.90 E-value: 3.46e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 243 AGVAHEIRNPLSSIKGLAKYFAERaPAGGEAHQLAQVMAKEADRLNRVVSELLElvkptHLALQA----VDLN------- 311
Cdd:PRK11466 449 AAMSHEIRTPLYGILGTAQLLADN-PALNAQRDDLRAITDSGESLLTILNDILD-----YSAIEAggknVSVSdepfepr 522
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 312 TLINHSLQLVSQDANCREIQLRFTANDTLPE-IQADPDRLTQVLLNLYLNAIQaIGQHGVISVTASESGAGVKISVTDSG 390
Cdd:PRK11466 523 PLLESTLQLMSGRVKGRPIRLATDIADDLPTaLMGDPRRIRQVITNLLSNALR-FTDEGSIVLRSRTDGEQWLVEVEDSG 601
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15834180 391 KGIAADQLEAIFTPY--FTTKAEGTGLGLAVVHNIVEQHGGTIQVASLEGKGARFTLWLPVNITRKDPQ 457
Cdd:PRK11466 602 CGIDPAKLAEIFQPFvqVSGKRGGTGLGLTISSRLAQAMGGELSATSTPEVGSCFCLRLPLRVATAPVP 670
|
|
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
241-449 |
3.78e-21 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 95.36 E-value: 3.78e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 241 LAAGVAHEIRNPLSSIKgLAkyfAERAPAGGEahQLAQVMAKEADRLNRVVSELLELVKP-THLALQAVDLNTLINHSLQ 319
Cdd:PRK09467 232 LMAGVSHDLRTPLTRIR-LA---TEMMSEEDG--YLAESINKDIEECNAIIEQFIDYLRTgQEMPMEMADLNALLGEVIA 305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 320 LVSQDAncREIQLRFtaNDTLPEIQADPDRLTQVLLNLYLNAIQAigQHGVISVTASESGAGVKISVTDSGKGIAADQLE 399
Cdd:PRK09467 306 AESGYE--REIETAL--QPGPIEVPMNPIAIKRALANLVVNAARY--GNGWIKVSSGTEGKRAWFQVEDDGPGIPPEQLK 379
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 15834180 400 AIFTPyFTT--KA---EGTGLGLAVVHNIVEQHGGTIQVASLEGKGARFTLWLPV 449
Cdd:PRK09467 380 HLFQP-FTRgdSArgsSGTGLGLAIVKRIVDQHNGKVELGNSEEGGLSARAWLPL 433
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
240-450 |
1.23e-20 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 95.09 E-value: 1.23e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 240 HLAAgVAHEIRNPLSSIKGlAKYFAERAPAGGEAHQLAQVMAKEADRLNRVVSELLELVK----PTHLALQAVDLNTLIN 315
Cdd:PRK15347 401 HLTT-ISHEIRTPLNGVLG-ALELLQNTPLTAEQMDLADTARQCTLSLLAIINNLLDFSRiesgQMTLSLEETALLPLLD 478
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 316 HSLQLVSQDANCREIQLRFTANDTLP-EIQADPDRLTQVLLNLYLNAIQaIGQHGVISVTASESGAGVKISVTDSGKGIA 394
Cdd:PRK15347 479 QAMLTIQGPAQSKSLTLRTFVGAHVPlYLHLDSLRLRQILVNLLGNAVK-FTETGGIRLRVKRHEQQLCFTVEDTGCGID 557
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 15834180 395 ADQLEAIFTPYFTT--KAEGTGLGLAVVHNIVEQHGGTIQVASLEGKGARFTLWLPVN 450
Cdd:PRK15347 558 IQQQQQIFTPFYQAdtHSQGTGLGLTIASSLAKMMGGELTLFSTPGVGSCFSLVLPLN 615
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
350-448 |
1.34e-20 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 86.61 E-value: 1.34e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 350 LTQVLLNLYLNAIQAigQHGVISVTASESGAGVKISVTDSGKGIAADQLEAIFTPYF------TTKAEGTGLGLAVVHNI 423
Cdd:cd16949 1 LARALENVLRNALRY--SPSKILLDISQDGDQWTITITDDGPGVPEDQLEQIFLPFYrvdsarDRESGGTGLGLAIAERA 78
|
90 100
....*....|....*....|....*
gi 15834180 424 VEQHGGTIQVASLEGKGARFTLWLP 448
Cdd:cd16949 79 IEQHGGKIKASNRKPGGLRVRIWLP 103
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
346-448 |
6.34e-20 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 84.51 E-value: 6.34e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 346 DPDRLTQVLLNLYLNAIQAIGQ------HGVISVTASESGAgVKISVTDSGKGIAADQLEAIFTPYFTTKAEGTGLGLAV 419
Cdd:cd16944 1 DTTQISQVLTNILKNAAEAIEGrpsdvgEVRIRVEADQDGR-IVLIVCDNGKGFPREMRHRATEPYVTTRPKGTGLGLAI 79
|
90 100
....*....|....*....|....*....
gi 15834180 420 VHNIVEQHGGTIQVASLEGKGARFTLWLP 448
Cdd:cd16944 80 VKKIMEEHGGRISLSNREAGGACIRIILP 108
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
346-448 |
8.04e-20 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 84.44 E-value: 8.04e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 346 DPDRLTQVLLNLYLNAIQAIGQHGVISVTASESGAGVKISVTDSGKGIAADQLEAIFTPYFTTK------AEGTGLGLAV 419
Cdd:cd16946 1 DRDRLQQLFVNLLENSLRYTDTGGKLRIRAAQTPQEVRLDVEDSAPGVSDDQLARLFERFYRVEssrnraSGGSGLGLAI 80
|
90 100
....*....|....*....|....*....
gi 15834180 420 VHNIVEQHGGTIQVASLEGKGARFTLWLP 448
Cdd:cd16946 81 CHNIALAHGGTISAEHSPLGGLRLVLTLP 109
|
|
| HATPase_Glnl-NtrB-like |
cd16918 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
350-448 |
1.98e-19 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli GlnL (synonyms NtrB and NRII); This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs), similar to Escherichia coli GlnL/NtrB/NRII HK of the two-component regulatory system (TCS) GlnL/GlnG (NtrB-NtrC, or NRII-NRI), which regulates the transcription of genes encoding metabolic enzymes and permeases in response to carbon and nitrogen status in E. coli and related bacteria. Also included in this family are Rhodobacter capsulatus NtrB, Azospirillum brasilense NtrB, Vibrio alginolyticus NtrB, Rhizobium leguminosarum biovar phaseoli NtrB, and Herbaspirillum seropedicae NtrB. Escherichia coli GlnL/NtrB/NRII is both a kinase and a phosphatase, catalyzing the phosphorylation and dephosphorylation of GlnG/NtrC/NRI. The kinase and phosphatase activities of GlnL/NtrB/NRII are regulated by the PII signal transduction protein, which on binding to GlnL/NtrB/NRII, inhibits the kinase activity of GlnL/NtrB/NRII and activates the GlnL/NtrB/NRII phosphatase activity. Proteins having this HATPase domain also have a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also contain PAS sensor domain(s).
Pssm-ID: 340395 [Multi-domain] Cd Length: 109 Bit Score: 83.22 E-value: 1.98e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 350 LTQVLLNLYLNAIQAI-GQHGVISVTASESGA----------GVKISVTDSGKGIAADQLEAIFTPYFTTKAEGTGLGLA 418
Cdd:cd16918 1 LIQVFLNLVRNAAQALaGSGGEIILRTRTQRQvtlghprhrlALRVSVIDNGPGIPPDLQDTIFYPMVSGRENGTGLGLA 80
|
90 100 110
....*....|....*....|....*....|
gi 15834180 419 VVHNIVEQHGGTIQVASLEGKgARFTLWLP 448
Cdd:cd16918 81 IAQNIVSQHGGVIECDSQPGH-TVFSVSLP 109
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
241-450 |
2.58e-19 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 90.87 E-value: 2.58e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 241 LAAGVAHEIRNPLSSIKGLAKYF-----AERAPAGGEAHQLAQVMakeadrLN--RVVSELLELVKPT----HLALQAVD 309
Cdd:PRK10490 667 LLAALSHDLRTPLTVLFGQAEILtldlaSEGSPHARQASEIRQQV------LNttRLVNNLLDMARIQsggfNLRKEWLT 740
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 310 LNTLINHSLQLVSQDANCREIQLRFTANDTLpeIQADPDRLTQVLLNLYLNAIQAIGQHGVISVTASESGAGVKISVTDS 389
Cdd:PRK10490 741 LEEVVGSALQMLEPGLSGHPINLSLPEPLTL--IHVDGPLFERVLINLLENAVKYAGAQAEIGIDAHVEGERLQLDVWDN 818
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15834180 390 GKGIAADQLEAIFTPYFTTKAE----GTGLGLAVVHNIVEQHGGTIQVASLEGKGARFTLWLPVN 450
Cdd:PRK10490 819 GPGIPPGQEQLIFDKFARGNKEsaipGVGLGLAICRAIVEVHGGTIWAENRPEGGACFRVTLPLE 883
|
|
| cpxA |
PRK09470 |
envelope stress sensor histidine kinase CpxA; |
245-453 |
4.77e-19 |
|
envelope stress sensor histidine kinase CpxA;
Pssm-ID: 236532 [Multi-domain] Cd Length: 461 Bit Score: 89.22 E-value: 4.77e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 245 VAHEIRNPLSSIKgLAKYFAERApaGGEAHQLAQVmAKEADRLNRVVSELLEL----VKpTHLALQAVDLNTLINHSLQL 320
Cdd:PRK09470 250 ISHELRTPLTRLQ-LATALLRRR--QGESKELERI-ETEAQRLDSMINDLLVLsrnqQK-NHLERETFKANSLWSEVLED 324
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 321 VSQDANCREIQLRFTANdtlPE---IQADPDRLTQVLLNLYLNAIQAIGQHgvISVTASESGAGVKISVTDSGKGIAADQ 397
Cdd:PRK09470 325 AKFEAEQMGKSLTVSAP---PGpwpINGNPNALASALENIVRNALRYSHTK--IEVAFSVDKDGLTITVDDDGPGVPEEE 399
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15834180 398 LEAIFTPYFTT------KAEGTGLGLAVVHNIVEQHGGTIQVASLEGKGARFTLWLPVNITR 453
Cdd:PRK09470 400 REQIFRPFYRVdeardrESGGTGLGLAIVENAIQQHRGWVKAEDSPLGGLRLTIWLPLYKRS 461
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
188-450 |
6.82e-19 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 88.92 E-value: 6.82e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 188 DREQRNTLIILFALATvLLASVLSFfwyrryLRSRQLLQdEMKR----KEKLVA--------------LGHLA------- 242
Cdd:PRK10549 159 DKQQRRTSWLIVALST-LLAALATF------LLARGLLA-PVKRlvegTHKLAAgdfttrvtptsrdeLGRLAqdfnqla 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 243 --------------AGVAHEIRNPLSSIKGLAKYFAE--RAPaggEAHQLAQVMAkEADRLNRVVSEL--LELVKPTHLA 304
Cdd:PRK10549 231 stlekneqmrrdfmADISHELRTPLAVLRGELEAIQDgvRKF---TPESVASLQA-EVGTLTKLVDDLhqLSLSDEGALA 306
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 305 LQ--AVDLNTLinhsLQLVSqdANCREI----QLRFTANdtLPE---IQADPDRLTQVLLNLYLNAIQAIGQHGVISVTA 375
Cdd:PRK10549 307 YRktPVDLVPL----LEVAG--GAFRERfasrGLTLQLS--LPDsatVFGDPDRLMQLFNNLLENSLRYTDSGGSLHISA 378
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 376 SESGAGVKISVTDSGKGIAADQLEAIFTPYFTTKAE------GTGLGLAVVHNIVEQHGGTIQVASLEGKGARFTLWLPV 449
Cdd:PRK10549 379 EQRDKTLRLTFADSAPGVSDEQLQKLFERFYRTEGSrnrasgGSGLGLAICLNIVEAHNGRIIAAHSPFGGVSITVELPL 458
|
.
gi 15834180 450 N 450
Cdd:PRK10549 459 E 459
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
243-448 |
7.95e-19 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 88.14 E-value: 7.95e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 243 AGVAHEIRNPLSSIKGLAKYFAERAPAGGEAHQLAQVMAKEADRLNRVVSELLELVK----PTHLALQAVDLNTLinhsL 318
Cdd:PRK11006 209 ANVSHELRTPLTVLQGYLEMMQDQPLEGALREKALHTMREQTQRMEGLVKQLLTLSKieaaPTIDLNEKVDVPMM----L 284
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 319 QLVSQDANC---REIQLRFTANDTLpEIQADPDRLTQVLLNLYLNAIQAIGQHGVISVTASESGAGVKISVTDSGKGIAA 395
Cdd:PRK11006 285 RVLEREAQTlsqGKHTITFEVDNSL-KVFGNEDQLRSAISNLVYNAVNHTPEGTHITVRWQRVPQGAEFSVEDNGPGIAP 363
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15834180 396 DQLEAI---FtpYFTTKAE-----GTGLGLAVVHNIVEQHGGTIQVASLEGKGARFTLWLP 448
Cdd:PRK11006 364 EHIPRLterF--YRVDKARsrqtgGSGLGLAIVKHALSHHDSRLEIESEVGKGTRFSFVLP 422
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
346-448 |
2.26e-18 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 80.23 E-value: 2.26e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 346 DPDRLTQVLLNLYLNAIQAIGQHGVISVTASESGA-GVKISVTDSGKGIAADQLEAIFTPY------FTTKAEGTGLGLA 418
Cdd:cd16925 1 DAEKYERVVLNLLSNAFKFTPDGGRIRCILEKFRLnRFLLTVSDSGPGIPPNLREEIFERFrqgdgsSTRAHGGTGLGLS 80
|
90 100 110
....*....|....*....|....*....|
gi 15834180 419 VVHNIVEQHGGTIQVASLEGKGARFTLWLP 448
Cdd:cd16925 81 IVKEFVELHGGTVTVSDAPGGGALFQVELP 110
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
244-457 |
3.53e-18 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 86.20 E-value: 3.53e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 244 GVAHEIRNPLSSIKglakYFAERAPAGGEAHQLAqvMAKEADRLNRVVSELL---ELVKP-THLALQAVDLNTLIN---H 316
Cdd:PRK10604 218 GIAHELRTPLVRLR----YRLEMSDNLSAAESQA--LNRDIGQLEALIEELLtyaRLDRPqNELHLSEPDLPAWLSthlA 291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 317 SLQLVSQDancREIQLrftanDTLPEIQ---ADPDRLTQVLLNLYLNAIQAigQHGVISVTASESGAGVKISVTDSGKGI 393
Cdd:PRK10604 292 DIQAVTPE---KTVRL-----DTPHQGDygaLDMRLMERVLDNLLNNALRY--AHSRVRVSLLLDGNQACLIVEDDGPGI 361
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 394 AADQLEAIFTPYFTTKAE------GTGLGLAVVHNIVEQHGGTIQVASLEGKGARFTLWLPVNITRKDPQ 457
Cdd:PRK10604 362 PPEERERVFEPFVRLDPSrdratgGCGLGLAIVHSIALAMGGSVNCDESELGGARFSFSWPVWHNLPQFT 431
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
350-448 |
5.25e-18 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 79.29 E-value: 5.25e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 350 LTQVLLNLYLNAIQAI--GQHGVISVTASESGAGVKISVTDSGKGIAADQLEAIFTPY----FTTKAEGTGLGLAVVHNI 423
Cdd:cd16921 1 LGQVLTNLLGNAIKFRrpRRPPRIEVGAEDVGEEWTFYVRDNGIGIDPEYAEKVFGIFqrlhSREEYEGTGVGLAIVRKI 80
|
90 100
....*....|....*....|....*
gi 15834180 424 VEQHGGTIQVASLEGKGARFTLWLP 448
Cdd:cd16921 81 IERHGGRIWLESEPGEGTTFYFTLP 105
|
|
| HATPase_DpiB-CitA-like |
cd16915 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
356-448 |
7.05e-18 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 DpiB, DcuS, and Bacillus subtilis CitS, DctS, and YufL; This family includes histidine kinase-like ATPase domains of Escherichia coli K-12 DpiB and DcuS, and Bacillus subtilis CitS, DctS and MalK histidine kinases (HKs) all of which are two component transduction systems (TCSs). E. coli K-12 DpiB (also known as CitA) is the histidine kinase (HK) of DpiA-DpiB, a two-component signal transduction system (TCS) required for the expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. E. coli K-12 DcuS (also known as YjdH) is the HK of DcuS-DcuR, a TCS that in the presence of the extracellular C4-dicarboxlates, activates the expression of the genes of anaerobic fumarate respiration and of aerobic C4-dicarboxylate uptake. CitS is the HK of Bacillus subtilis CitS-CitT, a TCS which regulates expression of CitM, the Mg-citrate transporter. Bacillus subtilis DctS forms a tripartite sensor unit (DctS/DctA/DctB) for sensing C4 dicarboxylates. Bacillus subtilis MalK (also known as YfuL) is the HK of MalK-MalR (YufL-YufM) a TCS which regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Proteins having this DpiB-CitA-like HATPase domain generally have sensor domains such as Cache and PAS, and a histidine kinase A (HisKA)-like SpoOB-type, alpha-helical domain.
Pssm-ID: 340392 [Multi-domain] Cd Length: 104 Bit Score: 78.87 E-value: 7.05e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 356 NLYLNAIQAIG----QHGVISVTASESGAGVKISVTDSGKGIAADQLEAIFTPYFTTKAEGT-GLGLAVVHNIVEQHGGT 430
Cdd:cd16915 7 NLIDNALDALAatgaPNKQVEVFLRDEGDDLVIEVRDTGPGIAPELRDKVFERGVSTKGQGErGIGLALVRQSVERLGGS 86
|
90
....*....|....*...
gi 15834180 431 IQVASLEGKGARFTLWLP 448
Cdd:cd16915 87 ITVESEPGGGTTFSIRIP 104
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
228-454 |
1.02e-17 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 86.33 E-value: 1.02e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 228 EMKRKEKL---VALGHLAAGVAHEIRNPLSSIKGLAKYFAERAPAGGEAHQLAQVMAKEADRLNRVVSELLELVKPT--- 301
Cdd:PRK09959 699 EVERNKAInatVAKSQFLATMSHEIRTPISSIMGFLELLSGSGLSKEQRVEAISLAYATGQSLLGLIGEILDVDKIEsgn 778
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 302 -HLALQAVDLNTLINHSLQLVSQDANCREIQLrfTANDTLPE---IQADPDRLTQVLLNLYLNAIQaIGQHGVISVTAS- 376
Cdd:PRK09959 779 yQLQPQWVDIPTLVQNTCHSFGAIAASKSIAL--SCSSTFPDhylVKIDPQAFKQVLSNLLSNALK-FTTEGAVKITTSl 855
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 377 ----ESGAGVKISVTDSGKGIAADQLEAIFTPYFTTKA----EGTGLGLAVVHNIVEQHGGTIQVASLEGKGARFTLWLP 448
Cdd:PRK09959 856 ghidDNHAVIKMTIMDSGSGLSQEEQQQLFKRYSQTSAgrqqTGSGLGLMICKELIKNMQGDLSLESHPGIGTTFTITIP 935
|
....*.
gi 15834180 449 VNITRK 454
Cdd:PRK09959 936 VEISQQ 941
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
242-448 |
1.11e-16 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 82.13 E-value: 1.11e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 242 AAGVAHEIRNPLSSIKGLAKYFAERAPAGGEAHQLAQVMAKEADRLNRVVSELLELVKPT----HLALQAVDLNTLINHS 317
Cdd:PRK09835 266 SADIAHEIRTPITNLITQTEIALSQSRSQKELEDVLYSNLEELTRMAKMVSDMLFLAQADnnqlIPEKKMLDLADEVGKV 345
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 318 LQLVSQDANCREIQLRFtaNDTLPEIQADPDRLTQVLLNLYLNAIQAIGQHGVISVTASESGAGVKISVTDSGKGIAADQ 397
Cdd:PRK09835 346 FDFFEAWAEERGVELRF--VGDPCQVAGDPLMLRRAISNLLSNALRYTPAGEAITVRCQEVDHQVQLVVENPGTPIAPEH 423
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 15834180 398 LEAIFTPYFTT------KAEGTGLGLAVVHNIVEQHGGTIQVASlEGKGARFTLWLP 448
Cdd:PRK09835 424 LPRLFDRFYRVdpsrqrKGEGSGIGLAIVKSIVVAHKGTVAVTS-DARGTRFVISLP 479
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
343-447 |
1.22e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 72.82 E-value: 1.22e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 343 IQADPDRLTQVLLNLYLNAIQAIGQHGVISVTASESgAGVKISVTDSGKGIAADQLEAIFTPYF---TTKAEGTGLGLAV 419
Cdd:cd16940 7 VQGDALLLFLLLRNLVDNAVRYSPQGSRVEIKLSAD-DGAVIRVEDNGPGIDEEELEALFERFYrsdGQNYGGSGLGLSI 85
|
90 100
....*....|....*....|....*...
gi 15834180 420 VHNIVEQHGGTIQVASLEGKGARFTLWL 447
Cdd:cd16940 86 VKRIVELHGGQIFLGNAQGGGLEAWVRL 113
|
|
| PRK11086 |
PRK11086 |
sensory histidine kinase DcuS; Provisional |
350-455 |
4.04e-15 |
|
sensory histidine kinase DcuS; Provisional
Pssm-ID: 236839 [Multi-domain] Cd Length: 542 Bit Score: 77.65 E-value: 4.04e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 350 LTQVLLNLYLNAIQAIGQ--HGVISVTASESGAGVKISVTDSGKGIAADQLEAIFTPYFTTKAEGTGLGLAVVHNIVEQH 427
Cdd:PRK11086 434 LITILGNLIENALEAVGGeeGGEISVSLHYRNGWLHCEVSDDGPGIAPDEIDAIFDKGYSTKGSNRGVGLYLVKQSVENL 513
|
90 100
....*....|....*....|....*...
gi 15834180 428 GGTIQVASLEGKGARFTLWLPVNITRKD 455
Cdd:PRK11086 514 GGSIAVESEPGVGTQFFVQIPWDGERSN 541
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
350-449 |
6.86e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 70.15 E-value: 6.86e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 350 LTQVLLNLYLNAIQAigQHGVISVTASESGAGVKISVTDSGKGIAADQLEAIFTPYF------TTKAEGTGLGLAVVHNI 423
Cdd:cd16939 1 MARALDNLLRNALRY--AHRTVRIALLVSGGRLTLIVEDDGPGIPAAARERVFEPFVrldpsrDRATGGFGLGLAIVHRV 78
|
90 100
....*....|....*....|....*.
gi 15834180 424 VEQHGGTIQVASLEGKGARFTLWLPV 449
Cdd:cd16939 79 ALWHGGHVECDDSELGGACFRLTWPR 104
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
350-448 |
1.39e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 69.40 E-value: 1.39e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 350 LTQVLLNLYLNAIQAIGqhGVISVTASESGAGVKISVTDSGKGIAADQLEAIFTPYFTTKA----EGTGLGLAVVHNIVE 425
Cdd:cd16950 1 LKRVLSNLVDNALRYGG--GWVEVSSDGEGNRTRIQVLDNGPGIAPEEVDELFQPFYRGDNargtSGTGLGLAIVQRISD 78
|
90 100
....*....|....*....|...
gi 15834180 426 QHGGTIQVASLEGKGARFTLWLP 448
Cdd:cd16950 79 AHGGSLTLANRAGGGLCARIELP 101
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
246-440 |
1.09e-13 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 72.76 E-value: 1.09e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 246 AHEIRNPLSSIKGLAKY--FAERAPAGGEaHQLAQvMAKEADRLNRVVSELLELVKPTHLA----LQAVDLNTLINHSLQ 319
Cdd:PRK10337 245 AHELRSPLAALKVQTEVaqLSDDDPQARK-KALLQ-LHAGIDRATRLVDQLLTLSRLDSLDnlqdVAEIPLEDLLQSAVM 322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 320 LVSQDANCREIQLRFTANDTLPEIQADPDRLTQVLLNLYLNAIQAIGQHGVISVTASESGagvkISVTDSGKGIAADQLE 399
Cdd:PRK10337 323 DIYHTAQQAGIDVRLTLNAHPVIRTGQPLLLSLLVRNLLDNAIRYSPQGSVVDVTLNARN----FTVRDNGPGVTPEALA 398
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 15834180 400 AIFTPYFT---TKAEGTGLGLAVVHNIVEQHGGTIQVASLEGKG 440
Cdd:PRK10337 399 RIGERFYRppgQEATGSGLGLSIVRRIAKLHGMNVSFGNAPEGG 442
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
350-448 |
3.69e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 65.67 E-value: 3.69e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 350 LTQVLLNLYLNAIQAI-GQHGVISVTASESGAGVKISVTDSGKGIAADQLEAIFTPYFTTKAEG------TGLGLAVVHN 422
Cdd:cd16953 1 LGQVLRNLIGNAISFSpPDTGRITVSAMPTGKMVTISVEDEGPGIPQEKLESIFDRFYTERPANeafgqhSGLGLSISRQ 80
|
90 100 110
....*....|....*....|....*....|
gi 15834180 423 IVEQHGGTIQVASLE----GKGARFTLWLP 448
Cdd:cd16953 81 IIEAHGGISVAENHNqpgqVIGARFTVQLP 110
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
194-450 |
6.27e-13 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 70.43 E-value: 6.27e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 194 TLIILFALATVLLASVLSFFWYRRYLRSRQLLQDEMKRKEKLVaLGHLAAGVAHEIRNPLSSIKGLA---KYFAERAPAG 270
Cdd:COG2972 157 RLILLIILLLLLLALLLSYLLSRSITRPIKRLKKAMKKVEKGD-LVRLEVSGNDEIGILARSFNEMVeriKELIEEVYEL 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 271 GEAHQLAQVMAKEAdRLNR--------VVSELLELVKPTHLALQAVDLNTLINHSLQLVSQD-------ANCR---EIQ- 331
Cdd:COG2972 236 ELEKKEAELKALQA-QINPhflfntlnSIRWLAELEDPEEAEEMLEALSKLLRYSLSKGDELvtleeelELIKsylEIQk 314
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 332 LRFtaNDTLP-EIQADPDRLTQVLLNLYL-----NAIQA----IGQHGVISVTASESGAGVKISVTDSGKGIAADQLEAI 401
Cdd:COG2972 315 LRF--GDRLEvEIEIDEELLDLLIPKLILqplveNAIEHgiepKEGGGTIRISIRKEGDRLVITVEDNGVGMPEEKLEKL 392
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 15834180 402 FTPyFTTKAEGTGLGLAVVHNIVEQH---GGTIQVASLEGKGARFTLWLPVN 450
Cdd:COG2972 393 LEE-LSSKGEGRGIGLRNVRERLKLYygeEYGLEIESEPGEGTTVTIRIPLE 443
|
|
| HATPase_PhoQ-like |
cd16954 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
309-443 |
2.19e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.
Pssm-ID: 340430 [Multi-domain] Cd Length: 135 Bit Score: 64.19 E-value: 2.19e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 309 DLNTLINhSLQLVSQDANcREIQLRFTANDTLPeiqADPDRLTQVLLNLYLNAIQ-AIGQhgvISVTASESGAGVKISVT 387
Cdd:cd16954 2 LLDSLCS-ALNKVYQRKG-VSISLDISPELRFP---GERNDLMELLGNLLDNACKwCLEF---VEVTARQTDGGLHLIVD 73
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 15834180 388 DSGKGIAADQLEAIFT--PYFTTKAEGTGLGLAVVHNIVEQHGGTIQVASLEGKGARF 443
Cdd:cd16954 74 DDGPGVPESQRSKIFQrgQRLDEQRPGQGLGLAIAKEIVEQYGGELSLSDSPLGGARF 131
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
235-299 |
2.31e-12 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 61.84 E-value: 2.31e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15834180 235 LVALGHLAAGVAHEIRNPLSSIKGLAKYFAERAPAGGEAHQLAQVMAKEADRLNRVVSELLELVK 299
Cdd:cd00082 1 LQAKGEFLANVSHELRTPLTAIRGALELLEEELLDDEEQREYLERIREEAERLLRLINDLLDLSR 65
|
|
| HATPase_CheA-like |
cd16916 |
Histidine kinase-like ATPase domain of the chemotaxis protein histidine kinase CheA, and some ... |
348-448 |
2.35e-12 |
|
Histidine kinase-like ATPase domain of the chemotaxis protein histidine kinase CheA, and some hybrid sensor histidine kinases; This family includes the cytoplasmic histidine kinase (HK) CheA, a transmembrane receptor which, together with cytoplasmic adaptor protein (CheW), forms the lattice at the core of the chemosensory array that controls the cellular chemotaxis of motile bacteria and archaea. CheA forms a two-component signal transduction system (TCS) with the response regulator CheY. Proteins having this CheA-like HATPase domain generally also have a histidine-phosphotransfer domain, a histidine kinase homodimeric domain, and a regulatory domain; some are hybrid sensor histidine kinases as they contain a REC signal receiver domain.
Pssm-ID: 340393 [Multi-domain] Cd Length: 178 Bit Score: 65.30 E-value: 2.35e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 348 DRLTQVLLNLYLNAI----------QAIGQ--HGVISVTASESGAGVKISVTDSGKGI---------------AADQLEA 400
Cdd:cd16916 37 EKLADPLTHLLRNAVdhgieapeerLAAGKppEGTITLRAEHQGNQVVIEVSDDGRGIdrekirekaiergliTADEAAT 116
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15834180 401 ---------IFTPYFTTKAE-----GTGLGLAVVHNIVEQHGGTIQVASLEGKGARFTLWLP 448
Cdd:cd16916 117 lsddevlnlIFAPGFSTAEQvtdvsGRGVGMDVVKRSIESLGGTIEVESEPGQGTTFTIRLP 178
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
237-299 |
9.70e-12 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 60.30 E-value: 9.70e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15834180 237 ALGHLAAGVAHEIRNPLSSIKGLAKyFAERAPAGGEAHQLAQVMAKEADRLNRVVSELLELVK 299
Cdd:pfam00512 1 AKSEFLANLSHELRTPLTAIRGYLE-LLRDEKLDEEQREYLETILRSAERLLRLINDLLDLSR 62
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
237-302 |
1.04e-11 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 59.89 E-value: 1.04e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15834180 237 ALGHLAAGVAHEIRNPLSSIKGLAKyFAERAPAGGEAHQLAQVMAKEADRLNRVVSELLELVKPTH 302
Cdd:smart00388 1 AKREFLANLSHELRTPLTAIRGYLE-LLLDTELSEEQREYLETILREAERLLRLINDLLDLSRIEA 65
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
346-447 |
1.36e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 60.94 E-value: 1.36e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 346 DPDRLTQVLLNLYLNAIQAIGQHGVISVTASESGAGVKISVTDSGKGIAADQLEAIFTPYFT-----TKAEGTGLGLAVV 420
Cdd:cd16945 1 DPFLLRQAINNLLDNAIDFSPEGGLIALQLEADTEGIELLVFDEGSGIPDYALNRVFERFYSlprphSGQKSTGLGLAFV 80
|
90 100
....*....|....*....|....*..
gi 15834180 421 HNIVEQHGGTIQVASLEGkGARFTLWL 447
Cdd:cd16945 81 QEVAQLHGGRITLRNRPD-GVLAFLTL 106
|
|
| HATPase_YcbM-like |
cd16947 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
344-447 |
1.37e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).
Pssm-ID: 340423 [Multi-domain] Cd Length: 125 Bit Score: 61.76 E-value: 1.37e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 344 QADPDRLTQVLLNLYLNAIQAIGQHGVISVTASESGAGVKISVTDSGKGIAADQLEAIFTPYFT------TKAEGTGLGL 417
Cdd:cd16947 15 NANTEALQRILKNLISNAIKYGSDGKFLGMTLREDEKHVYIDIWDKGKGISETEKDHVFERLYTledsrnSAKQGNGLGL 94
|
90 100 110
....*....|....*....|....*....|
gi 15834180 418 AVVHNIVEQHGGTIQVASLEGKGARFTLWL 447
Cdd:cd16947 95 TITKRLAESMGGSIYVNSKPYEKTVFTVTL 124
|
|
| CheA |
COG0643 |
Chemotaxis protein histidine kinase CheA [Signal transduction mechanisms]; |
369-449 |
1.47e-11 |
|
Chemotaxis protein histidine kinase CheA [Signal transduction mechanisms];
Pssm-ID: 440408 [Multi-domain] Cd Length: 563 Bit Score: 66.36 E-value: 1.47e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 369 GVISVTASESGAGVKISVTDSGKGI---------------AADQLEA---------IFTPYFTTKAE-----GTGLGLAV 419
Cdd:COG0643 309 GTITLSAYHEGGRVVIEVSDDGRGLdlekirakaiekgliTAEEAAAlsdeellelIFAPGFSTAEEvtdlsGRGVGMDV 388
|
90 100 110
....*....|....*....|....*....|
gi 15834180 420 VHNIVEQHGGTIQVASLEGKGARFTLWLPV 449
Cdd:COG0643 389 VKTNIEALGGTIEIESEPGKGTTFTLRLPL 418
|
|
| PRK10841 |
PRK10841 |
two-component system sensor histidine kinase RcsC; |
243-448 |
3.06e-11 |
|
two-component system sensor histidine kinase RcsC;
Pssm-ID: 182772 [Multi-domain] Cd Length: 924 Bit Score: 65.77 E-value: 3.06e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 243 AGVAHEIRNPLSSIKG-LAKYFAERAPAGgeAHQLAQVMAKEADRLNRVVSELLelvkpthlalqavDLNTLINHSLQLV 321
Cdd:PRK10841 452 ATVSHELRTPLYGIIGnLDLLQTKELPKG--VDRLVTAMNNSSSLLLKIISDIL-------------DFSKIESEQLKIE 516
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 322 SQDANCREIQLRFTANdTLP-------------------EIQADPDRLTQVLLNLYLNAIQaIGQHGVISVTASESGAGV 382
Cdd:PRK10841 517 PREFSPREVINHITAN-YLPlvvkkrlglycfiepdvpvALNGDPMRLQQVISNLLSNAIK-FTDTGCIVLHVRVDGDYL 594
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15834180 383 KISVTDSGKGIAADQLEAIFTPYFTTKA------EGTGLGLAVVHNIVEQHGGTIQVASLEGKGARFTLWLP 448
Cdd:PRK10841 595 SFRVRDTGVGIPAKEVVRLFDPFFQVGTgvqrnfQGTGLGLAICEKLINMMDGDISVDSEPGMGSQFTIRIP 666
|
|
| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
223-455 |
3.70e-11 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 64.22 E-value: 3.70e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 223 QLLQ--DEMKRKEKLvalghLAAGVAHEIRNPLSSIKgLAKYFAERApaggeAHQLAQVMAKEADRLNRVVSELLELVKP 300
Cdd:PRK10755 125 QLVSrlTSTLDQERL-----FTADVAHELRTPLAGIR-LHLELLEKQ-----HHIDVAPLIARLDQMMHTVEQLLQLARA 193
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 301 TH-LA---LQAVDL-NTLINHSLQLVSQDANCREIQLRFTANDTLPEIQADPDRLTQVLLNLYLNAIQAIGQHGVISVTA 375
Cdd:PRK10755 194 GQsFSsghYQTVKLlEDVILPSQDELSEMLEQRQQTLLLPESAADITVQGDATLLRLLLRNLVENAHRYSPEGSTITIKL 273
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 376 SESGAGVKISVTDSGKGIAADQLEAIFTPY--FTTKAEGTGLGLAVVHNIVEQHGGTIQVAS-LEGKGARFTLWLPVNIT 452
Cdd:PRK10755 274 SQEDGGAVLAVEDEGPGIDESKCGELSKAFvrMDSRYGGIGLGLSIVSRITQLHHGQFFLQNrQERSGTRAWVWLPKAQN 353
|
...
gi 15834180 453 RKD 455
Cdd:PRK10755 354 VAN 356
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
356-448 |
5.85e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 59.14 E-value: 5.85e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 356 NLYLNAIQAIGQHGVISVTASESGAGVKISVTDSGKGIAADQLEAIFTPYFTTKAE------GTGLGLAVVHNIVEQHGG 429
Cdd:cd16952 7 NLVSNAVKYTPPSDTITVRWSQEESGARLSVEDTGPGIPPEHIPRLTERFYRVDIErcrntgGTGLGLAIVKHVMSRHDA 86
|
90
....*....|....*....
gi 15834180 430 TIQVASLEGKGARFTLWLP 448
Cdd:cd16952 87 RLLIASELGKGSRFTCLFP 105
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
346-446 |
9.10e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 58.63 E-value: 9.10e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 346 DPDRLTQVLLNLYLNAIQAIGQHGVISVTASESGAGVKISVTDSGKGIAADQLEAIFTPYFTTKAEGT-----GLGLAVV 420
Cdd:cd16975 1 DTLLLSRALINIISNACQYAPEGGTVSISIYDEEEYLYFEIWDNGHGFSEQDLKKALELFYRDDTSRRsgghyGMGLYIA 80
|
90 100
....*....|....*....|....*.
gi 15834180 421 HNIVEQHGGTIQVASLEGKGARFTLW 446
Cdd:cd16975 81 KNLVEKHGGSLIIENSQKGGAEVTVK 106
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
360-448 |
1.52e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 58.07 E-value: 1.52e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 360 NAIQAIGQHGVISVTASESGAGVKISVTDSGKGIAADQLEAIFTPYFTTK-----AEGTGLGLAVVHNIVEQHGGTIQVA 434
Cdd:cd16948 16 NALKYSKQGGKIEIYSETNEQGVVLSIKDFGIGIPEEDLPRVFDKGFTGEngrnfQESTGMGLYLVKKLCDKLGHKIDVE 95
|
90
....*....|....
gi 15834180 435 SLEGKGARFTLWLP 448
Cdd:cd16948 96 SEVGEGTTFTITFP 109
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
350-448 |
3.71e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 56.63 E-value: 3.71e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 350 LTQVLLNLYLNAIQAIGQHGVISVTASESGAGVKISVTDSGKGIAADQLEAIFTPYF----TTKAEGTGLGLAVVHNIVE 425
Cdd:cd16923 1 LQRVFSNLLSNAIKYSPENTRIYITSFLTDDVVNIMFKNPSSHPLDFKLEKLFERFYrgdnSRNTEGAGLGLSIAKAIIE 80
|
90 100
....*....|....*....|...
gi 15834180 426 QHGGTIQvASLEGKGARFTLWLP 448
Cdd:cd16923 81 LHGGSAS-AEYDDNHDLFKVRLP 102
|
|
| ComP |
COG4585 |
Signal transduction histidine kinase ComP [Signal transduction mechanisms]; |
195-449 |
1.39e-09 |
|
Signal transduction histidine kinase ComP [Signal transduction mechanisms];
Pssm-ID: 443642 [Multi-domain] Cd Length: 252 Bit Score: 58.48 E-value: 1.39e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 195 LIILFALATVLLASVLSFFWYR-RYLRSRQLLQDEMKRKEKLVALG---HLAA----GVAHEirnpLSSIK---GLAKYF 263
Cdd:COG4585 7 LGALALLVGALLGLLLALVLLRaRRAERAAELERELAARAEEAREEerrRIARelhdGVGQS----LSAIKlqlEAARRL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 264 AERAPAggEAHQLAQVMAKEADRLNRVVSELLELVKPThlALQAVDLNTLINHSLQLVSQDANcreIQLRFTANDTLPEI 343
Cdd:COG4585 83 LDADPE--AAREELEEIRELAREALAELRRLVRGLRPP--ALDDLGLAAALEELAERLLRAAG---IRVELDVDGDPDRL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 344 QADpdrltqVLLNLYL-------NAIQaigqHG---VISVTASESGAGVKISVTDSGKGIAADQleaiftpyfttkAEGT 413
Cdd:COG4585 156 PPE------VELALYRivqealtNALK----HAgatRVTVTLEVDDGELTLTVRDDGVGFDPEA------------APGG 213
|
250 260 270
....*....|....*....|....*....|....*.
gi 15834180 414 GLGLAVVHNIVEQHGGTIQVASLEGKGARFTLWLPV 449
Cdd:COG4585 214 GLGLRGMRERAEALGGTLTIGSAPGGGTRVRATLPL 249
|
|
| COG3920 |
COG3920 |
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction ... |
305-449 |
8.89e-09 |
|
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms];
Pssm-ID: 443125 [Multi-domain] Cd Length: 495 Bit Score: 57.61 E-value: 8.89e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 305 LQAVDLNTLINHSLQLVSQDANCREIQLRFTAndtlPEIQADPDRLTQV--LLN-LYLNAIQ---AIGQHGVISVTASES 378
Cdd:COG3920 356 WEGVDLRDYLRELLEPLRDSYGGRGIRIELDG----PDVELPADAAVPLglILNeLVTNALKhafLSGEGGRIRVSWRRE 431
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15834180 379 GAGVKISVTDSGKGIAADqleaiftpyfTTKAEGTGLGLAVVHNIVEQHGGTIQVASleGKGARFTLWLPV 449
Cdd:COG3920 432 DGRLRLTVSDNGVGLPED----------VDPPARKGLGLRLIRALVRQLGGTLELDR--PEGTRVRITFPL 490
|
|
| PRK11107 |
PRK11107 |
hybrid sensory histidine kinase BarA; Provisional |
346-452 |
9.11e-08 |
|
hybrid sensory histidine kinase BarA; Provisional
Pssm-ID: 236848 [Multi-domain] Cd Length: 919 Bit Score: 54.47 E-value: 9.11e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 346 DPDRLTQVLLNLYLNAIQaIGQHGVISV---TASESGAGV--KISVTDSGKGIAADQLEAIFTPYftTKAE--------G 412
Cdd:PRK11107 405 DPLRLQQIITNLVGNAIK-FTESGNIDIlveLRALSNTKVqlEVQIRDTGIGISERQQSQLFQAF--RQADasisrrhgG 481
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 15834180 413 TGLGLAVVHNIVEQHGGTIQVASLEGKGARFTLWLPVNIT 452
Cdd:PRK11107 482 TGLGLVITQKLVNEMGGDISFHSQPNRGSTFWFHLPLDLN 521
|
|
| HATPase_YpdA-YehU-LytS-like |
cd16924 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
360-448 |
6.70e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli YpdA, YehU, Bacillus subtilis LytS, and some hybrid sensor histidine kinases; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis LytS, a HK of the two-component system (TCS) LytS-LytR needed for growth on pyruvate, and Staphylococcus aureus LytS-LytR TCS involved in the adaptation of S. aureus to cationic antimicrobial peptides. It also includes the HATPase domains of Escherichia coli YpdA and YehU, HKs of YpdA-YpdB and YehU-YehTCSs, which are involved together in a nutrient sensing regulatory network. Proteins having this HATPase domain also contain a histidine kinase domain (His-kinase), some having accessory sensor domain(s) such as Cache, HAMP or GAF; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340401 [Multi-domain] Cd Length: 103 Bit Score: 42.05 E-value: 6.70e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 360 NAIQAIGQH----GVISVTASESGAGVKISVTDSGKGIAADQLEAIftpyFTTKAEGTGLGLAVVHNIV-----EQHGgt 430
Cdd:cd16924 12 NAIQHGLSPltdkGVVTISALKEDNHVMIEVEDNGRGIDPKVLNIL----GKKPKEGNGIGLYNVHQRLillfgEDYG-- 85
|
90
....*....|....*...
gi 15834180 431 IQVASLEGKGARFTLWLP 448
Cdd:cd16924 86 IHIASEPDKGTRITFTIP 103
|
|
| HATPase_AgrC-ComD-like |
cd16935 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
310-433 |
7.88e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Staphylococcus aureus AgrC and Streptococcus pneumoniae ComD which are involved in quorum sensing; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) including Staphylococcus aureus AgrC which is an HK of the accessory gene regulator (agr) quorum sensing two-component regulatory system (TCS) AgrC-AgrA. The agr system plays a part in the transition from persistent to virulent phenotype. This family also includes Streptococcus pneumoniae ComD HK of the ComD-ComE TCS, involved in quorum sensing and genetic competence.
Pssm-ID: 340412 [Multi-domain] Cd Length: 134 Bit Score: 42.56 E-value: 7.88e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 310 LNTLINHSLQLvsqdanCREIQLRFTAN-DTLPEIQADPDRLTQVLLNLYLNAIQA----IGQHGVISVTASESGAGVKI 384
Cdd:cd16935 2 LDSLLSEKLEL------AREKGIEFTIEiDIPILLPISPLDLCIIFGNLLDNAIEAcakiDKENRFIHLKIRQKKGFLII 75
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 15834180 385 SVTDSGKGiaadQLEAIFTPYFTTKAE-GTGLGLAVVHNIVEQHGGTIQV 433
Cdd:cd16935 76 SIENSYEG----ELKKKNGLFLSTKKDkNHGIGLKSIREIVKKYNGNLSI 121
|
|
| PRK10815 |
PRK10815 |
two-component system sensor histidine kinase PhoQ; |
371-442 |
7.90e-05 |
|
two-component system sensor histidine kinase PhoQ;
Pssm-ID: 182754 [Multi-domain] Cd Length: 485 Bit Score: 45.01 E-value: 7.90e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15834180 371 ISVTASESGAGVKISVTDSGKGIAADQLEAIFT--PYFTTKAEGTGLGLAVVHNIVEQHGGTIQVASLEGKGAR 442
Cdd:PRK10815 398 VEISARQTDEHLHIVVEDDGPGIPESKRELIFDrgQRADTLRPGQGLGLSVAREITEQYEGKISAGDSPLGGAR 471
|
|
| sCache_3_2 |
pfam17203 |
Single cache domain 3; This domain is associated to sensor histidine kinases and recognizes ... |
40-157 |
2.30e-04 |
|
Single cache domain 3; This domain is associated to sensor histidine kinases and recognizes citrate and TCA cycle intermediates, Ag(II), Zn(II), Mg(II) (Matilla et al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).
Pssm-ID: 435783 [Multi-domain] Cd Length: 140 Bit Score: 41.24 E-value: 2.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 40 RETAAARQTLLEKGSVLIRAL--ESGSRVGMGMRMHHAQQQALLEEMAGQPGVRWFAVTDEQGTIVMHSNSGMVGKQLYS 117
Cdd:pfam17203 1 QLRADLTRQLERRALALARSVaaSPVVRVALTDPEPYPGLQALVESVRRITGADYVVIADRRGRVLAHPDPERVGRRLSG 80
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 15834180 118 PQEMQQLhPGDEEVWRRIDSADGePVLEIYRqfqPMFAAG 157
Cdd:pfam17203 81 PATAPAL-TAGRSYTGTVTGTLG-PSLDAKL---PIFDAD 115
|
|
| RsbW |
COG2172 |
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; |
317-426 |
4.11e-04 |
|
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms];
Pssm-ID: 441775 [Multi-domain] Cd Length: 127 Bit Score: 40.28 E-value: 4.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 317 SLQLVSQDANCREIQLRFTAndTLPEIQADPDRLTQVLLNLY---LNAIQ---AIGQHGVISVTASESGAGVKISVTDSG 390
Cdd:COG2172 1 SLSLPADLEDLGLARRAVRA--LLRELGLDEDDADDLVLAVSeavTNAVRhayGGDPDGPVEVELELDPDGLEIEVRDEG 78
|
90 100 110
....*....|....*....|....*....|....*.
gi 15834180 391 KGIAADQLEaiftPYFTTKAEGtGLGLAVVHNIVEQ 426
Cdd:COG2172 79 PGFDPEDLP----DPYSTLAEG-GRGLFLIRRLMDE 109
|
|
| dpiB |
PRK15053 |
sensor histidine kinase DpiB; Provisional |
340-448 |
4.90e-04 |
|
sensor histidine kinase DpiB; Provisional
Pssm-ID: 185013 [Multi-domain] Cd Length: 545 Bit Score: 42.51 E-value: 4.90e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 340 LPEiQADPDRLTQVLLNLYLNAIQAIGQ----HGVISVTASESGAGVKISVTDSGKGIAADQLEAIFTPYFTTKAEGT-- 413
Cdd:PRK15053 424 LPP-GLDSTEFAAIVGNLLDNAFEASLRsdegNKIVELFLSDEGDDVVIEVADQGCGVPESLRDKIFEQGVSTRADEPge 502
|
90 100 110
....*....|....*....|....*....|....*.
gi 15834180 414 -GLGLAVVHNIVEQHGGTIQVASLEGKGARFTLWLP 448
Cdd:PRK15053 503 hGIGLYLIASYVTRCGGVITLEDNDPCGTLFSIFIP 538
|
|
| PRK10547 |
PRK10547 |
chemotaxis protein CheA; Provisional |
363-448 |
1.14e-03 |
|
chemotaxis protein CheA; Provisional
Pssm-ID: 236712 [Multi-domain] Cd Length: 670 Bit Score: 41.25 E-value: 1.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 363 QAIGQHGV--ISVTASESGAGVKISVTDSGKGIAADQLEA---------------------IFTPYFTTkAE------GT 413
Cdd:PRK10547 409 LAAGKNSVgnLILSAEHQGGNICIEVTDDGAGLNRERILAkaasqglavsenmsdeevgmlIFAPGFST-AEqvtdvsGR 487
|
90 100 110
....*....|....*....|....*....|....*
gi 15834180 414 GLGLAVVHNIVEQHGGTIQVASLEGKGARFTLWLP 448
Cdd:PRK10547 488 GVGMDVVKRNIQEMGGHVEIQSKQGKGTTIRILLP 522
|
|
| HATPase_SpoIIAB-like |
cd16942 |
Histidine kinase-like ATPase domain of SpoIIAB, an anti sigma-F factor and serine-protein ... |
329-445 |
3.92e-03 |
|
Histidine kinase-like ATPase domain of SpoIIAB, an anti sigma-F factor and serine-protein kinase involved in regulating sigma-F during sporulation in Bacilli, and related domains; This family includes histidine kinase-like ATPase (HATPase) domain of SpoIIAB, an anti sigma-F factor and a serine-protein kinase involved in regulating sigma-F during sporulation in Bacilli where, early in sporulation, the cell divides into two unequal compartments: a larger mother cell and a smaller forespore. Sigma-F transcription factor is activated in the forespore directly after the asymmetric septum forms, and its spatial and temporal activation is required for sporulation. Free sigma-F can associate with the RNA polymerase core and activate transcription of the sigma-F regulon, its regulation may comprise a partner-switching mechanism involving SpoIIAB, SpoIIAA, and sigma-F as follows: SpoIIAB can form alternative complexes with either: i) sigma-F, holding it in an inactive form and preventing its association with RNA polymerase, or ii) unphosphorylated SpoIIAA and a nucleotide, either ATP or ADP. In the presence of ATP, SpoIIAB acts as a kinase to specifically phosphorylate a serine residue of SpoIIAA; this phosphorylated form has low affinity for SpoIIAB and dissociates, making SpoIIAB available to capture sigma-F. SpoIIAA may then be dephosphorylated by a SpoIIE serine phosphatase and be free to attack the SpoIIAB sigma-F complex to induce the release of sigma-F.
Pssm-ID: 340418 [Multi-domain] Cd Length: 135 Bit Score: 37.52 E-value: 3.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 329 EIQLRFTA---NDTLPEI-------QADP--DRLTQ---VLLNLYLNA-IQAIGQ--HGVISVTASESGAGVKISVTDSG 390
Cdd:cd16942 3 EMHLQFSArseNESFARVtvaafvaQLDPtiDELTEiktVVSEAVTNAiIHGYNNdpNGIVSISVIIEDGVVHLTVRDEG 82
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 15834180 391 KGIaaDQLEAIFTPYFTTKA--EGTGLGLAVVHNIVEQhggtIQVASLEGKGARFTL 445
Cdd:cd16942 83 VGI--PDIEEARQPLFTTKPelERSGMGFTIMENFMDE----VIVESEVNKGTTVYL 133
|
|
| HATPase_EL346-LOV-HK-like |
cd16951 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
350-448 |
4.36e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Erythrobacter litoralis blue light-activated histidine kinase 2; This domain family includes the histidine kinase-like ATPase (HATPase) domain of blue light-activated histidine kinase 2 of Erythrobacter litoralis (EL346). Signaling commonly occurs within HK dimers, however EL346 functions as a monomer. Also included in this family are the HATPase domains of ethanolamine utilization sensory transduction histidine kinase (EutW), whereby regulation of ethanolamine, a carbon and nitrogen source for gut bacteria, results in autophosphorylation and subsequent phosphoryl transfer to a response regulator (EutV) containing an RNA-binding domain. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory PAS sensor domain, while some have an N-terminal histidine kinase domain.
Pssm-ID: 340427 [Multi-domain] Cd Length: 131 Bit Score: 37.40 E-value: 4.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 350 LTQVLLNLYLNAIQAiGQHGVISVTASESGAGVKISVTDSGKGIaadqleaiftPYFTTKAEGTGLGLAVVHNIVEQHGG 429
Cdd:cd16951 44 VNELLQNALKHAFSD-REGGTITIRSVVDGDYLRITVIDDGVGL----------PQDEDWPNKGSLGLQIVRSLVEGELK 112
|
90
....*....|....*....
gi 15834180 430 TIQVASLEGKGARFTLWLP 448
Cdd:cd16951 113 AFLEVQSAENGTRVNIDIP 131
|
|
| PRK10618 |
PRK10618 |
phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional |
247-448 |
4.46e-03 |
|
phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional
Pssm-ID: 236726 [Multi-domain] Cd Length: 894 Bit Score: 39.53 E-value: 4.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 247 HEIRNPLSSIKGLAKYFAERAPAGGEAHQLAQvMAKEADRLNRVVSEL-----LELV--KPTHlalQAVDLNTLINHSLQ 319
Cdd:PRK10618 459 DELKQPLQSLAQLAAQLRQTSDEEQQQPELDQ-LAEQSDVLVRLVDNIqllnmLETQdwKPEQ---ELFSLQDLIDEVLP 534
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 320 LVSQDANCREIQLrFTANDTLPEIQADPDR--LTQVLLNLYLNAIqAIGQHGVIS--VTASESGAG-VKISVTDSGKGIA 394
Cdd:PRK10618 535 EVLPAIKRKGLQL-LIHNHLKAEQLRIGDRdaLRKILLLLLNYAI-TTTAYGKITleVDQDESSPDrLTIRILDTGAGVS 612
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 15834180 395 ADQLEAIFTPYFTTKAE-----GTGLGLAVVHNIVEQHGGTIQVASLEGKGARFTLWLP 448
Cdd:PRK10618 613 IKELDNLHFPFLNQTQGdrygkASGLTFFLCNQLCRKLGGHLTIKSREGLGTRYSIHLK 671
|
|
| HATPase_c_5 |
pfam14501 |
GHKL domain; This family represents the structurally related ATPase domains of histidine ... |
350-433 |
6.07e-03 |
|
GHKL domain; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 433996 [Multi-domain] Cd Length: 102 Bit Score: 36.04 E-value: 6.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15834180 350 LTQVLLNLYLNAIQA---IGQHGVISVTASESGAGVKISV--TDSGKGIAADQLeaiftPYFTTKAEGTGLGLAVVHNIV 424
Cdd:pfam14501 6 LCVIFGNLLDNAIEAcskIDDNRFIRLKIREKQNFLIIRIenTYEGELKFEGKL-----PSTKTKGDGHGIGLKSIRRIV 80
|
....*....
gi 15834180 425 EQHGGTIQV 433
Cdd:pfam14501 81 KKYGGNLST 89
|
|
| |
