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Conserved domains on  [gi|270288740|ref|NP_387502|]
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amine oxidase [flavin-containing] A [Rattus norvegicus]

Protein Classification

flavin monoamine oxidase family protein( domain architecture ID 11440890)

flavin monoamine oxidase family protein functions as an oxidoreductase that catalyzes the transfer of electrons from one molecule, the electron donor or reductant, to another molecule, the electron acceptor or oxidant

CATH:  3.50.50.60|1.10.405.10
EC:  1.-.-.-
Gene Ontology:  GO:0000166|GO:0016491
SCOP:  4000128

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
11-464 5.18e-129

Monoamine oxidase [Amino acid transport and metabolism];


:

Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 383.12  E-value: 5.18e-129
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740  11 GHMFDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVK-WVDVGGAYVGPTQNRILRLSKELGIETY 89
Cdd:COG1231    5 ARGKDVVIVGAGLAGLAAARELRKAGLDVTVLEARDRVGGRVWTLRFGDDGlYAELGAMRIPPSHTNLLALARELGLPLE 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740  90 K-VNVNERLVQYVKGKTYPFRGAfppvwnPLAYLDYNNLWRTMDE-MGKEIPvdaPWQARhAQEWDKMTMKDLIDKICWT 167
Cdd:COG1231   85 PfPNENGNALLYLGGKRVRAGEI------AADLRGVAELLAKLLRaLAAALD---PWAHP-AAELDRESLAEWLRRNGAS 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 168 KTAREFAYLFVNINVTSEPHEVSALWFLWYVRQCGGtarifsvtnGGQERKFVGGSGQVSEQIMGLLGDKVKLSSPVTYI 247
Cdd:COG1231  155 PSARRLLGLLGAGEYGADPDELSLLDLLRYAASAGG---------GAQQFRIVGGMDQLPRALAAELGDRIRLGAPVTRI 225

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 248 DQTDDNIIVETLNHEHYECKYVISAIPPILTAKIHFKPELPPERNQLIQRLPMGAVIKCMVYYKEAFWKKKDYCGCMIIE 327
Cdd:COG1231  226 RQDGDGVTVTTDDGGTVRADAVIVTVPPSVLRRIEFDPPLPAAKRAAIQRLPYGAAIKVFLQFDRPFWEEDGLYGGISLT 305

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 328 DEeaPIAITLDDTKP-DGSLPAIMGFILARKADRLAKLHKDIRKRKICELYAKVLGSqEALYPVHYEEKNWCEEQYSGGC 406
Cdd:COG1231  306 DL--PIRQTWYPSNGpDGGAGVLLGYVGGDDARALAALSPEERVAAALEQLARIFGV-YAAEPVDYVSTDWGRDPWSRGA 382

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 270288740 407 YtAYFPPGIMTQYGRVIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAREVLNALG 464
Cdd:COG1231  383 Y-AAAPPGQLTAAGPALAEPDGRIHFAGEHTSDEWPGWVEGALESGERAAAEILARLG 439
 
Name Accession Description Interval E-value
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
11-464 5.18e-129

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 383.12  E-value: 5.18e-129
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740  11 GHMFDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVK-WVDVGGAYVGPTQNRILRLSKELGIETY 89
Cdd:COG1231    5 ARGKDVVIVGAGLAGLAAARELRKAGLDVTVLEARDRVGGRVWTLRFGDDGlYAELGAMRIPPSHTNLLALARELGLPLE 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740  90 K-VNVNERLVQYVKGKTYPFRGAfppvwnPLAYLDYNNLWRTMDE-MGKEIPvdaPWQARhAQEWDKMTMKDLIDKICWT 167
Cdd:COG1231   85 PfPNENGNALLYLGGKRVRAGEI------AADLRGVAELLAKLLRaLAAALD---PWAHP-AAELDRESLAEWLRRNGAS 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 168 KTAREFAYLFVNINVTSEPHEVSALWFLWYVRQCGGtarifsvtnGGQERKFVGGSGQVSEQIMGLLGDKVKLSSPVTYI 247
Cdd:COG1231  155 PSARRLLGLLGAGEYGADPDELSLLDLLRYAASAGG---------GAQQFRIVGGMDQLPRALAAELGDRIRLGAPVTRI 225

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 248 DQTDDNIIVETLNHEHYECKYVISAIPPILTAKIHFKPELPPERNQLIQRLPMGAVIKCMVYYKEAFWKKKDYCGCMIIE 327
Cdd:COG1231  226 RQDGDGVTVTTDDGGTVRADAVIVTVPPSVLRRIEFDPPLPAAKRAAIQRLPYGAAIKVFLQFDRPFWEEDGLYGGISLT 305

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 328 DEeaPIAITLDDTKP-DGSLPAIMGFILARKADRLAKLHKDIRKRKICELYAKVLGSqEALYPVHYEEKNWCEEQYSGGC 406
Cdd:COG1231  306 DL--PIRQTWYPSNGpDGGAGVLLGYVGGDDARALAALSPEERVAAALEQLARIFGV-YAAEPVDYVSTDWGRDPWSRGA 382

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 270288740 407 YtAYFPPGIMTQYGRVIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAREVLNALG 464
Cdd:COG1231  383 Y-AAAPPGQLTAAGPALAEPDGRIHFAGEHTSDEWPGWVEGALESGERAAAEILARLG 439
Amino_oxidase pfam01593
Flavin containing amine oxidoreductase; This family consists of various amine oxidases, ...
 23-460 1.02e-80

Flavin containing amine oxidoreductase; This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.


Pssm-ID: 396255 [Multi-domain]  Cd Length: 446  Bit Score: 258.96  E-value: 1.02e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740   23 ISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVkWVDVGGAYVGPTQNRILRLSKELGIET---YKVNVNERLVQ 99
Cdd:pfam01593   1 LAGLAAARELLRAGHDVTVLEARDRVGGRIRTVRDDGF-LIELGAMWFHGAQPPLLALLKELGLEDrlvLPDPAPFYTVL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740  100 YVKGKTYPFRGAFPP-VWNPLAYLDYNNLW-----RTMDEMGKEIPVDAPWQARHAQEWDKMTMKD-LIDKICWTKTARE 172
Cdd:pfam01593  80 FAGGRRYPGDFRRVPaGWEGLLEFGRLLSIpeklrLGLAALASDALDEFDLDDFSLAESLLFLGRRgPGDVEVWDRLIDP 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740  173 FAYLFVNINVT------SEPHEVSALWFLWYVRQcggtarifsvtNGGQERKFVGGSGQVSEQI-MGLLGDKVKLSSPVT 245
Cdd:pfam01593 160 ELFAALPFASGafagdpSELSAGLALPLLWALLG-----------EGGSLLLPRGGLGALPDALaAQLLGGDVRLNTRVR 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740  246 YIDQTDDNIIVETLNHEHYECKYVISAIPPILTAKIHFKPELPPERNQLIQRLPMGAVIKCMVYYKEAFWKKKDYCGCMI 325
Cdd:pfam01593 229 SIDREGDGVTVTLTDGEVIEADAVIVTVPLGVLKRILFTPPLPPEKARAIRNLGYGPVNKVHLEFDRKFWPDLGLLGLLS 308

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740  326 IEDEEAPIA---ITLDDTKPDGSLPAIMGFI-LARKADRLAKLHKDIRKRKICELYAKVLGSqEALYPVHYEEKNWCEEQ 401
Cdd:pfam01593 309 ELLTGLGTAfswLTFPNRAPPGKGLLLLVYVgPGDRARELEGLSDEELLQAVLRDLRKLFGE-EAPEPLRVLVSDWHTDP 387

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 270288740  402 YSGGCYTAYFPPGIMTQYGRVIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAREVL 460
Cdd:pfam01593 388 WPRGSYSLPQYGPGHDDYRPLARTPDPGLFFAGEHTSTGYPGTVEGAIESGRRAARAVL 446
PLN02268 PLN02268
probable polyamine oxidase
 16-458 2.48e-21

probable polyamine oxidase


Pssm-ID: 177909 [Multi-domain]  Cd Length: 435  Bit Score: 96.30  E-value: 2.48e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740  16 VVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVKwVDVGGAYV-GPTQ-NRILRLSKELGIETYKVNV 93
Cdd:PLN02268   3 VIVIGGGIAGIAAARALHDASFKVTLLESRDRIGGRVHTDYSFGFP-VDMGASWLhGVCNeNPLAPLIGRLGLPLYRTSG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740  94 NERLVQYVKGKTYpfrgafppvwnPLAYLDYNNLWR-TMDEMGK--EIPVDAPWQARHAQEWDkMTMKDLIdkicwtkta 170
Cdd:PLN02268  82 DNSVLYDHDLESY-----------ALFDMDGNQVPQeLVTKVGEtfERILEETEKVRDEHEED-MSLLQAI--------- 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 171 refaylfvNINVTSEP--------HEVsalwFLWYVRQCGG----TARIFSVTNGGQERKFVGGSGQVS---EQIMGLL- 234
Cdd:PLN02268 141 --------SIVLERHPelrleglaHEV----LQWYLCRMEGwfaaDADTISLKSWDQEELLEGGHGLMVrgyDPVINTLa 208

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 235 -GDKVKLSSPVTYIDQTDDNIIVETLNHEHYECKYVISAIP-PILTAK-IHFKPELPPERNQLIQRLPMGAVIKCMVYYK 311
Cdd:PLN02268 209 kGLDIRLNHRVTKIVRRYNGVKVTVEDGTTFVADAAIIAVPlGVLKANiIKFEPELPEWKEEAISDLGVGIENKIALHFD 288

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 312 EAFWKKKDYCGCMiiedEEAPIAIT--LDDTKPDGSlPAIMGFILARKADRLAKLHKDIRKRKICELYAKVLgsQEALYP 389
Cdd:PLN02268 289 SVFWPNVEFLGVV----APTSYGCSyfLNLHKATGH-PVLVYMPAGRLARDIEKLSDEAAANFAMSQLKKML--PDATEP 361

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 270288740 390 VHYEEKNWCEEQYSGGCYTAYFPPGIMTQYGRvIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAARE 458
Cdd:PLN02268 362 VQYLVSRWGSDPNSLGCYSYDLVGKPHDLYER-LRAPVDNLFFAGEATSSDFPGSVHGAYSTGVMAAEE 429
proto_IX_ox TIGR00562
protoporphyrinogen oxidase; This enzyme oxidizes protoporphyrinogen IX to protoporphyrin IX, a ...
 13-298 2.59e-11

protoporphyrinogen oxidase; This enzyme oxidizes protoporphyrinogen IX to protoporphyrin IX, a precursor of heme and chlorophyll. Bacillus subtilis HemY also has coproporphyrinogen III to coproporphyrin III oxidase activity in a heterologous expression system, although the role for this activity in vivo is unclear. This protein is a flavoprotein and has a beta-alpha-beta dinucleotide binding motif near the amino end. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin]


Pssm-ID: 213540 [Multi-domain]  Cd Length: 462  Bit Score: 65.63  E-value: 2.59e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740   13 MFDVVVIGGGISGLAAA----KLLSEYKINVLVLEARDRVGGRTYTVRNEHVKWvDVGGAYVGPTQNRILRLSKELGIET 88
Cdd:TIGR00562   2 KKHVVIIGGGISGLCAAyyleKEIPELPVELTLVEASDRVGGKIQTVKEDGYLI-ERGPDSFLERKKSAPDLVKDLGLEH 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740   89 YKVN--VNERLVQYVKGKTYPfrgaFPPVWNPLAYLDYNNL---WRT-MDEM-----GKEIPVDAPWQARHAQEW----- 152
Cdd:TIGR00562  81 VLVSdaTGQRYVLVNRGKLMP----VPTKIAPFVKTGLFSLggkLRAgMDFIrpaspGKDESVEEFVRRRFGDEVvenli 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740  153 ------------DKMTMKDLIDKIcwTKTAREFAYLFVNINVTSEPHEvsalwflwyvrqcGGTARIFSVTNGGQERKFV 220
Cdd:TIGR00562 157 epllsgiyagdpSKLSLKSTFPKF--YQTEQKHGSLILGMKKTRNLPQ-------------GSGLQLTAKKQGQDFQTLA 221

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 270288740  221 GGSGQVSEQIMGLLG-DKVKLSSPVTYIDQTDDNIIVETLNHEHYECKYVISAIPPILTAKIhfkpeLPPERNQLIQRL 298
Cdd:TIGR00562 222 TGLETLPEEIEKRLKlTKVYKGTKVTKLSHRGSNYTLELDNGVTVETDSVVVTAPHKAAAGL-----LSELSNSASSHL 295
AlaDh_PNT_C smart01002
Alanine dehydrogenase/PNT, C-terminal domain; Alanine dehydrogenase catalyzes the ...
 16-70 5.85e-03

Alanine dehydrogenase/PNT, C-terminal domain; Alanine dehydrogenase catalyzes the NAD-dependent reversible reductive amination of pyruvate into alanine.


Pssm-ID: 214966 [Multi-domain]  Cd Length: 149  Bit Score: 37.49  E-value: 5.85e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 270288740    16 VVVIGGGISGLAAAKLLSEYKINVLVL--------EARDRVGGRTYTVR------NEHVKWVD--VGGAYV 70
Cdd:smart01002  23 VVVIGAGVVGLGAAATAKGLGAEVTVLdvrparlrQLESLLGARFTTLYsqaellEEAVKEADlvIGAVLI 93
 
Name Accession Description Interval E-value
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
11-464 5.18e-129

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 383.12  E-value: 5.18e-129
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740  11 GHMFDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVK-WVDVGGAYVGPTQNRILRLSKELGIETY 89
Cdd:COG1231    5 ARGKDVVIVGAGLAGLAAARELRKAGLDVTVLEARDRVGGRVWTLRFGDDGlYAELGAMRIPPSHTNLLALARELGLPLE 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740  90 K-VNVNERLVQYVKGKTYPFRGAfppvwnPLAYLDYNNLWRTMDE-MGKEIPvdaPWQARhAQEWDKMTMKDLIDKICWT 167
Cdd:COG1231   85 PfPNENGNALLYLGGKRVRAGEI------AADLRGVAELLAKLLRaLAAALD---PWAHP-AAELDRESLAEWLRRNGAS 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 168 KTAREFAYLFVNINVTSEPHEVSALWFLWYVRQCGGtarifsvtnGGQERKFVGGSGQVSEQIMGLLGDKVKLSSPVTYI 247
Cdd:COG1231  155 PSARRLLGLLGAGEYGADPDELSLLDLLRYAASAGG---------GAQQFRIVGGMDQLPRALAAELGDRIRLGAPVTRI 225

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 248 DQTDDNIIVETLNHEHYECKYVISAIPPILTAKIHFKPELPPERNQLIQRLPMGAVIKCMVYYKEAFWKKKDYCGCMIIE 327
Cdd:COG1231  226 RQDGDGVTVTTDDGGTVRADAVIVTVPPSVLRRIEFDPPLPAAKRAAIQRLPYGAAIKVFLQFDRPFWEEDGLYGGISLT 305

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 328 DEeaPIAITLDDTKP-DGSLPAIMGFILARKADRLAKLHKDIRKRKICELYAKVLGSqEALYPVHYEEKNWCEEQYSGGC 406
Cdd:COG1231  306 DL--PIRQTWYPSNGpDGGAGVLLGYVGGDDARALAALSPEERVAAALEQLARIFGV-YAAEPVDYVSTDWGRDPWSRGA 382

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 270288740 407 YtAYFPPGIMTQYGRVIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAREVLNALG 464
Cdd:COG1231  383 Y-AAAPPGQLTAAGPALAEPDGRIHFAGEHTSDEWPGWVEGALESGERAAAEILARLG 439
Amino_oxidase pfam01593
Flavin containing amine oxidoreductase; This family consists of various amine oxidases, ...
 23-460 1.02e-80

Flavin containing amine oxidoreductase; This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.


Pssm-ID: 396255 [Multi-domain]  Cd Length: 446  Bit Score: 258.96  E-value: 1.02e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740   23 ISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVkWVDVGGAYVGPTQNRILRLSKELGIET---YKVNVNERLVQ 99
Cdd:pfam01593   1 LAGLAAARELLRAGHDVTVLEARDRVGGRIRTVRDDGF-LIELGAMWFHGAQPPLLALLKELGLEDrlvLPDPAPFYTVL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740  100 YVKGKTYPFRGAFPP-VWNPLAYLDYNNLW-----RTMDEMGKEIPVDAPWQARHAQEWDKMTMKD-LIDKICWTKTARE 172
Cdd:pfam01593  80 FAGGRRYPGDFRRVPaGWEGLLEFGRLLSIpeklrLGLAALASDALDEFDLDDFSLAESLLFLGRRgPGDVEVWDRLIDP 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740  173 FAYLFVNINVT------SEPHEVSALWFLWYVRQcggtarifsvtNGGQERKFVGGSGQVSEQI-MGLLGDKVKLSSPVT 245
Cdd:pfam01593 160 ELFAALPFASGafagdpSELSAGLALPLLWALLG-----------EGGSLLLPRGGLGALPDALaAQLLGGDVRLNTRVR 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740  246 YIDQTDDNIIVETLNHEHYECKYVISAIPPILTAKIHFKPELPPERNQLIQRLPMGAVIKCMVYYKEAFWKKKDYCGCMI 325
Cdd:pfam01593 229 SIDREGDGVTVTLTDGEVIEADAVIVTVPLGVLKRILFTPPLPPEKARAIRNLGYGPVNKVHLEFDRKFWPDLGLLGLLS 308

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740  326 IEDEEAPIA---ITLDDTKPDGSLPAIMGFI-LARKADRLAKLHKDIRKRKICELYAKVLGSqEALYPVHYEEKNWCEEQ 401
Cdd:pfam01593 309 ELLTGLGTAfswLTFPNRAPPGKGLLLLVYVgPGDRARELEGLSDEELLQAVLRDLRKLFGE-EAPEPLRVLVSDWHTDP 387

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 270288740  402 YSGGCYTAYFPPGIMTQYGRVIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAREVL 460
Cdd:pfam01593 388 WPRGSYSLPQYGPGHDDYRPLARTPDPGLFFAGEHTSTGYPGTVEGAIESGRRAARAVL 446
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 13-463 6.59e-25

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 107.23  E-value: 6.59e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740  13 MFDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVkWVDVGG-AYVgPTQNRILRLSKELGIETYKV 91
Cdd:COG1232    1 MKRVAVIGGGIAGLTAAYRLAKAGHEVTVLEASDRVGGLIRTVEVDGF-RIDRGPhSFL-TRDPEVLELLRELGLGDELV 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740  92 NVNERLVQ-YVKGKTYPF-RGAFPPVWNPL--------AYLDY--NNLWRTMDE---------MGKEIpvdapwqarhaq 150
Cdd:COG1232   79 WPNTRKSYiYYGGKLHPLpQGPLALLRSPLlslagklrALLELlaPRRPPGEDEslaefvrrrFGREV------------ 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 151 eWDKMtMKDLIDKIcwtktareFAYlfvninvtsEPHEVSALWFLWYVRQ---------CGGTARIFSVTNGGQERKFVG 221
Cdd:COG1232  147 -YERL-VEPLLEGV--------YAG---------DPDELSADWAFPRLKRlelehgsliKGALALRKGAKAGEVFGYLRG 207

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 222 GSGQVSEQIMGLLGD-KVKLSSPVTYIDQTDDNIIVETLNHEHYECKYVISAIPPILTAKIhFKPeLPPERNQLIQRLPM 300
Cdd:COG1232  208 GLGTLVEALAEALEAgEIRLGTRVTAIEREGGGWRVTTSDGETIEADAVVSATPAPALARL-LAP-LPPEVAAALAGIPY 285

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 301 GAVIkcMVY--YKEAFWKKKDYCGCMIIEDEEAPI-AITLDDTK-----PDG--SLPAIMGFilARKADRLAKLHKDIRK 370
Cdd:COG1232  286 ASVA--VVAlgFDRPDLPPPDGFGWLVPRDEGVPIlAVTFSSNKwphraPDGkvLLRLEVGG--AGDPELWQLSDEELVA 361

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 371 RKICELyAKVLGSQEAlyPVHYEEKNWcEE---QYSGGcYTAYFPPgimtqygrvIRQPVGR---IYFAGtetaTQWSGY 444
Cdd:COG1232  362 LALADL-RKLLGIDAE--PVDTRVVRW-PKaypQYTVG-HLERVAA---------IREALAAlpgLYLAG----RAYDGV 423

                        490       500
                 ....*....|....*....|
gi 270288740 445 -MEGAVEAGERAAREVLNAL 463
Cdd:COG1232  424 gLPDCIRSGREAAERILAEL 443
PLN02268 PLN02268
probable polyamine oxidase
 16-458 2.48e-21

probable polyamine oxidase


Pssm-ID: 177909 [Multi-domain]  Cd Length: 435  Bit Score: 96.30  E-value: 2.48e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740  16 VVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVKwVDVGGAYV-GPTQ-NRILRLSKELGIETYKVNV 93
Cdd:PLN02268   3 VIVIGGGIAGIAAARALHDASFKVTLLESRDRIGGRVHTDYSFGFP-VDMGASWLhGVCNeNPLAPLIGRLGLPLYRTSG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740  94 NERLVQYVKGKTYpfrgafppvwnPLAYLDYNNLWR-TMDEMGK--EIPVDAPWQARHAQEWDkMTMKDLIdkicwtkta 170
Cdd:PLN02268  82 DNSVLYDHDLESY-----------ALFDMDGNQVPQeLVTKVGEtfERILEETEKVRDEHEED-MSLLQAI--------- 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 171 refaylfvNINVTSEP--------HEVsalwFLWYVRQCGG----TARIFSVTNGGQERKFVGGSGQVS---EQIMGLL- 234
Cdd:PLN02268 141 --------SIVLERHPelrleglaHEV----LQWYLCRMEGwfaaDADTISLKSWDQEELLEGGHGLMVrgyDPVINTLa 208

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 235 -GDKVKLSSPVTYIDQTDDNIIVETLNHEHYECKYVISAIP-PILTAK-IHFKPELPPERNQLIQRLPMGAVIKCMVYYK 311
Cdd:PLN02268 209 kGLDIRLNHRVTKIVRRYNGVKVTVEDGTTFVADAAIIAVPlGVLKANiIKFEPELPEWKEEAISDLGVGIENKIALHFD 288

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 312 EAFWKKKDYCGCMiiedEEAPIAIT--LDDTKPDGSlPAIMGFILARKADRLAKLHKDIRKRKICELYAKVLgsQEALYP 389
Cdd:PLN02268 289 SVFWPNVEFLGVV----APTSYGCSyfLNLHKATGH-PVLVYMPAGRLARDIEKLSDEAAANFAMSQLKKML--PDATEP 361

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 270288740 390 VHYEEKNWCEEQYSGGCYTAYFPPGIMTQYGRvIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAARE 458
Cdd:PLN02268 362 VQYLVSRWGSDPNSLGCYSYDLVGKPHDLYER-LRAPVDNLFFAGEATSSDFPGSVHGAYSTGVMAAEE 429
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 13-301 1.14e-20

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 94.92  E-value: 1.14e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740  13 MFDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTV-RNEHVkwVDVGGAYVGPTQ--NRILRlskELGIETY 89
Cdd:COG1233    3 MYDVVVIGAGIGGLAAAALLARAGYRVTVLEKNDTPGGRARTFeRPGFR--FDVGPSVLTMPGvlERLFR---ELGLEDY 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740  90 kVNVNERLVQYvkgkTYPFRGAfppvwnplAYLD-YNNLWRTMDEMGKEIPVDA--------PWQARHAQEWDKM----- 155
Cdd:COG1233   78 -LELVPLDPAY----RVPFPDG--------RALDlPRDLERTAAELERLFPGDAeayrrflaELRRLYDALLEDLlyrpl 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 156 -TMKDLIDKICW-------TKTAREF------------AYLFVNINVTSEPHEVSAL-WFLWYVRQCGGTARIfsvtngg 214
Cdd:COG1233  145 lSLRDLLRPLALarllrllLRSLRDLlrryfkdprlraLLAGQALYLGLSPDRTPALyALIAYLEYAGGVWYP------- 217

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 215 qerkfVGGSGQVSEQIMGL---LGDKVKLSSPVTYIDQTDDNII-VETLNHEHYECKYVISAIPPILTAKIHFKPE-LPP 289
Cdd:COG1233  218 -----KGGMGALADALARLaeeLGGEIRTGAEVERILVEGGRATgVRLADGEEIRADAVVSNADPAHTYLRLLGEEaLPA 292

                        330
                 ....*....|..
gi 270288740 290 ERNQLIQRLPMG 301
Cdd:COG1233  293 RYRRRLERFRYS 304
PLN02676 PLN02676
polyamine oxidase
 14-470 1.97e-19

polyamine oxidase


Pssm-ID: 215362 [Multi-domain]  Cd Length: 487  Bit Score: 91.31  E-value: 1.97e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740  14 FDVVVIGGGISGLAAAKLLSEYKI-NVLVLEARDRVGGRTYTVRNEHVKwVDVGGAYV----GPTQNRILRLSKELGIET 88
Cdd:PLN02676  27 PSVIIVGAGMSGISAAKTLSEAGIeDILILEATDRIGGRMRKANFAGVS-VELGANWVegvgGPESNPIWELANKLKLRT 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740  89 YKVNV-NERLVQYVK-GKTYPfrgafppvwNPLAYlDYNNLWRTMDEMGKEipVDAPWQARHAQEWDKMTMKDLIDKIcw 166
Cdd:PLN02676 106 FYSDFdNLSSNIYKQdGGLYP---------KKVVQ-KSMKVADASDEFGEN--LSISLSAKKAVDISILTAQRLFGQV-- 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 167 TKTAREFAYLFVNINVT-SEPHEVSALwflwyvrqcGGTARIFSVTNGGQERKFVGGSG-------QVSEQIM----GLL 234
Cdd:PLN02676 172 PKTPLEMVIDYYNYDYEfAEPPRVTSL---------KNTEPNPTFVDFGEDEYFVADPRgyeslvyYLAEQFLstksGKI 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 235 GD-KVKLSSPVTYIDQTDDNIIVETLNHEHYECKYVI-SAIPPIL-TAKIHFKPELPPERNQLIQRLPMGAVIKCMVYYK 311
Cdd:PLN02676 243 TDpRLKLNKVVREISYSKNGVTVKTEDGSVYRAKYVIvSVSLGVLqSDLIKFKPPLPDWKIEAIYQFDMAVYTKIFLKFP 322

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 312 EAFWKkkdyCG----CMIIEDEEA---PIAITLDDTKPDGSLpaIMGFILARKADRLAKLHKDIRKRKICELYAKVLGSQ 384
Cdd:PLN02676 323 YKFWP----SGpgteFFLYAHERRgyyPFWQHLENEYPGSNV--LFVTVTDEESRRIEQQPDSETKAEIMEVLRKMFGPN 396

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 385 -----EALYPvhyeekNWCEEQYSGGCYTAYfPPGIMTQYGRVIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAREV 459
Cdd:PLN02676 397 ipeatDILVP------RWWSNRFFKGSYSNW-PIGVSRYEFDQIRAPVGRVYFTGEHTSEKYNGYVHGAYLAGIDTANDL 469

                        490
                 ....*....|.
gi 270288740 460 LNALGKVAKKD 470
Cdd:PLN02676 470 LECIKKKKCRK 480
PRK07233 PRK07233
hypothetical protein; Provisional
 16-308 1.58e-18

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 88.02  E-value: 1.58e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740  16 VVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVkWVDVGGAYVGPTQNRILRLSKELGIEtykvnvnE 95
Cdd:PRK07233   2 IAIVGGGIAGLAAAYRLAKRGHEVTVFEADDQLGGLAASFEFGGL-PIERFYHHIFKSDEALLELLDELGLE-------D 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740  96 RLV-------QYVKGKTYPFRgafppvwNPLAYLDYNNLwRTMDE--MGKEIpvdapWQARHAQEW---DKMTMKDLIDK 163
Cdd:PRK07233  74 KLRwretktgYYVDGKLYPLG-------TPLELLRFPHL-SLIDKfrLGLLT-----LLARRIKDWralDKVPAEEWLRR 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 164 ICWTKTAREFaylFvninvtsEP----------HEVSALWFLWYVRqcggtARIFSVTNGGQERK--FVGGSGQVSEQIM 231
Cdd:PRK07233 141 WSGEGVYEVF---W-------EPlleskfgdyaDDVSAAWLWSRIK-----RRGNRRYSLFGEKLgyLEGGFATLIDALA 205

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 232 GLL---GDKVKLSSPVTYIDQTDDNIIVETLNHEHYECKYVISAIPPILTAKIhfKPELPPERNQLIQRLP-MGAVikCM 307
Cdd:PRK07233 206 EAIearGGEIRLGTPVTSVVIDGGGVTGVEVDGEEEDFDAVISTAPPPILARL--VPDLPADVLARLRRIDyQGVV--CM 281


                 .
gi 270288740 308 V 308
Cdd:PRK07233 282 V 282
COG3349 COG3349
Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function ...
 13-467 4.51e-15

Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function prediction only];


Pssm-ID: 442577 [Multi-domain]  Cd Length: 445  Bit Score: 77.20  E-value: 4.51e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740  13 MFDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNE----------HVKWvdvgGAYvgptQNrILRLSK 82
Cdd:COG3349    3 PPRVVVVGGGLAGLAAAVELAEAGFRVTLLEARPRLGGRARSFPDPdtglpidngqHVLL----GCY----RN-TLDLLR 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740  83 ELGIETYKVNVNERLVQYVKGKTYPFR-GAFPPVWNPLAYL---------DYNNLWRTMdemgkeipvdAPWQARHAQEW 152
Cdd:COG3349   74 RIGAADNLVGPEPLQFPLPGGRRWTLRaPRLPAPLHLLRALlrapglslaDRLALLRLL----------TACRERRWREL 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 153 DKMTMKDLIDKICWTKTARE-----FAYLFVNInvtsEPHEVSALWFLWYVRQ---CGGTARIFSVTNGGQERKFVGGSG 224
Cdd:COG3349  144 DDISVADWLRRHGQSPRLIRrlwepLLLAALNT----PPEQASARLALTVLREtllAGPAASDLLVPRGPLSELFVDPAL 219

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 225 QVSEQimglLGDKVKLSSPVTYIDQTDDNIIVETLNH-EHYECKYVISAIPPILTAKIhfkpeLPPERN----QLIQRLP 299
Cdd:COG3349  220 AYLEA----RGGEVRLGTRVRALEFDGGRVTGLVLADgETVPADAVVLAVPPEVAARL-----LPELARlpelGLLAPLE 290

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 300 MGAVIKCMVYYKEAfwkkkdycgcmIIEDEEAPIAI-------TLDDTKPDGSLPAIMGFILArKADRLAKL-HKDIRKR 371
Cdd:COG3349  291 YSPIVNVHLWLDRP-----------VTLGPPPFAGLvgstsqwVFDRGAGDGGQGGVLSVVIS-AADRLLDLsREELAAE 358

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 372 KICELyAKVLGSQEALYPVHYE---EKnwceeqysggcyTAYF---P------PGIMTqygrvirqPVGRIYFAGTETAT 439
Cdd:COG3349  359 VWAEL-AALLPAAREALPVWSRvvrEK------------RATFaatPgsdrlrPGART--------PIPNLFLAGDWTAT 417

                        490       500
                 ....*....|....*....|....*...
gi 270288740 440 QWSGYMEGAVEAGERAAREVLNALGKVA 467
Cdd:COG3349  418 GLPATMEGAVRSGRRAANAILARLGRPA 445
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
18-84 1.02e-13

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 66.02  E-value: 1.02e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 270288740   18 VIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVKwVDVGG-AYVGPTQNRILRLSKEL 84
Cdd:pfam13450   1 IVGAGLAGLVAAALLAKRGFRVLVLEKRDRLGGNAYSYRVPGYV-FDYGAhIFHGSDEPNVRDLLDEL 67
PLN02328 PLN02328
lysine-specific histone demethylase 1 homolog
 4-485 3.67e-13

lysine-specific histone demethylase 1 homolog


Pssm-ID: 215187 [Multi-domain]  Cd Length: 808  Bit Score: 72.33  E-value: 3.67e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740   4 LEKPNlaghmfdVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEH---VKWVDVGGAYV-GPTQNRILR 79
Cdd:PLN02328 236 VEPAN-------VVVVGAGLAGLVAARQLLSMGFKVVVLEGRARPGGRVKTMKMKGdgvVAAADLGGSVLtGINGNPLGV 308

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740  80 LSKELGIETYKVnvnerlvqyvkgktypfRGAFPpvwnplAYLDYNNLwrtmdemgkeipVDAPWQARHAQEWDKmtmkd 159
Cdd:PLN02328 309 LARQLGLPLHKV-----------------RDICP------LYLPDGKA------------VDAEIDSKIEASFNK----- 348

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 160 LIDKICWTKTA--REFAYLFVNI-----------NVTSEPHEVSAL-WFLWYVRQCGGT-ARIFSVTNGGQERKFVGGSG 224
Cdd:PLN02328 349 LLDRVCKLRQAmiEEVKSVDVNLgtaleafrhvyKVAEDPQERMLLnWHLANLEYANASlMSNLSMAYWDQDDPYEMGGD 428

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 225 QV-----SEQIMGLLGDKVKL--SSPVTYIDQTDDNIIVETLNHEhYECKYVISAIPPILTAK--IHFKPELPPERNQLI 295
Cdd:PLN02328 429 HCfipggNDTFVRELAKDLPIfyERTVESIRYGVDGVIVYAGGQE-FHGDMVLCTVPLGVLKKgsIEFYPELPQRKKDAI 507

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 296 QRLPMGAVIKCMVYYKEAFWKKK-DYCGcMIIEDEEAPIAITLDDTKPDGS-LPAIMGFILARKADRLAKLHKdirkrki 373
Cdd:PLN02328 508 QRLGYGLLNKVALLFPYNFWGGEiDTFG-HLTEDPSMRGEFFLFYSYSSVSgGPLLIALVAGDAAVKFETLSP------- 579

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 374 CELYAKVLGSQEALY---------PVHYEEKNWCEEQYSGGCYTaYFPPGIMTQYGRVIRQPV--GRIYFAGTETATQWS 442
Cdd:PLN02328 580 VESVKRVLQILRGIFhpkgivvpdPVQAVCTRWGKDCFTYGSYS-YVAVGSSGDDYDILAESVgdGRVFFAGEATNKQYP 658

                        490       500       510       520
                 ....*....|....*....|....*....|....*....|...
gi 270288740 443 GYMEGAVEAGeraAREVLNALGKVAKKDIWVEEPESKDVPAIE 485
Cdd:PLN02328 659 ATMHGAFLSG---MREAANILRVARRRSLCIDDKVNNDEEEDD 698
proto_IX_ox TIGR00562
protoporphyrinogen oxidase; This enzyme oxidizes protoporphyrinogen IX to protoporphyrin IX, a ...
 13-298 2.59e-11

protoporphyrinogen oxidase; This enzyme oxidizes protoporphyrinogen IX to protoporphyrin IX, a precursor of heme and chlorophyll. Bacillus subtilis HemY also has coproporphyrinogen III to coproporphyrin III oxidase activity in a heterologous expression system, although the role for this activity in vivo is unclear. This protein is a flavoprotein and has a beta-alpha-beta dinucleotide binding motif near the amino end. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin]


Pssm-ID: 213540 [Multi-domain]  Cd Length: 462  Bit Score: 65.63  E-value: 2.59e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740   13 MFDVVVIGGGISGLAAA----KLLSEYKINVLVLEARDRVGGRTYTVRNEHVKWvDVGGAYVGPTQNRILRLSKELGIET 88
Cdd:TIGR00562   2 KKHVVIIGGGISGLCAAyyleKEIPELPVELTLVEASDRVGGKIQTVKEDGYLI-ERGPDSFLERKKSAPDLVKDLGLEH 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740   89 YKVN--VNERLVQYVKGKTYPfrgaFPPVWNPLAYLDYNNL---WRT-MDEM-----GKEIPVDAPWQARHAQEW----- 152
Cdd:TIGR00562  81 VLVSdaTGQRYVLVNRGKLMP----VPTKIAPFVKTGLFSLggkLRAgMDFIrpaspGKDESVEEFVRRRFGDEVvenli 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740  153 ------------DKMTMKDLIDKIcwTKTAREFAYLFVNINVTSEPHEvsalwflwyvrqcGGTARIFSVTNGGQERKFV 220
Cdd:TIGR00562 157 epllsgiyagdpSKLSLKSTFPKF--YQTEQKHGSLILGMKKTRNLPQ-------------GSGLQLTAKKQGQDFQTLA 221

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 270288740  221 GGSGQVSEQIMGLLG-DKVKLSSPVTYIDQTDDNIIVETLNHEHYECKYVISAIPPILTAKIhfkpeLPPERNQLIQRL 298
Cdd:TIGR00562 222 TGLETLPEEIEKRLKlTKVYKGTKVTKLSHRGSNYTLELDNGVTVETDSVVVTAPHKAAAGL-----LSELSNSASSHL 295
PLN02529 PLN02529
lysine-specific histone demethylase 1
 16-462 3.60e-11

lysine-specific histone demethylase 1


Pssm-ID: 178144 [Multi-domain]  Cd Length: 738  Bit Score: 65.68  E-value: 3.60e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740  16 VVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTV---RNEHVKWVDVGGAYV-GPTQNRILRLSKELGIETYKV 91
Cdd:PLN02529 163 VIIVGAGLAGLAAARQLLSFGFKVVVLEGRNRPGGRVYTQkmgRKGQFAAVDLGGSVItGIHANPLGVLARQLSIPLHKV 242

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740  92 NVNerlvqyvkgktypfrgafPPVWNPLAYLdynnlwrtmdeMGKEIpvDAPWQARHAQEWDKMT-----MKDLIDKICW 166
Cdd:PLN02529 243 RDN------------------CPLYKPDGAL-----------VDKEI--DSNIEFIFNKLLDKVTelrqiMGGFANDISL 291

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 167 TKTAREFAYLFVNINVTSEPHEVSalWFLWYVRQC-GGTARIFSVTNGGQERKF-VGG-----SGQVSEQIMGLL-GDKV 238
Cdd:PLN02529 292 GSVLERLRQLYGVARSTEERQLLD--WHLANLEYAnAGCLSDLSAAYWDQDDPYeMGGdhcflAGGNWRLINALCeGVPI 369

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 239 KLSSPVTYIDQTDDNIIVeTLNHEHYECKYVISAIPPILTAK--IHFKPELPPERNQLIQRLPMGAVIKCMVYYKEAFWK 316
Cdd:PLN02529 370 FYGKTVDTIKYGNDGVEV-IAGSQVFQADMVLCTVPLGVLKKrtIRFEPELPRRKLAAIDRLGFGLLNKVAMVFPSVFWG 448

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 317 KK-DYCGCMiiedEEAPIA------ITLDDTKPDGslPAIMGFILARKADRLAKLHKDIrkrkiceLYAKVLGSQEALY- 388
Cdd:PLN02529 449 EElDTFGCL----NESSNKrgefflFYGYHTVSGG--PALVALVAGEAAQRFENTDPST-------LLHRVLSVLRGIYn 515

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 389 --------PVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYGRVIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAREVL 460
Cdd:PLN02529 516 pkginvpdPIQTICTRWGSDPLSYGSYSHVRVQSSGSDYDILAESVSGRLFFAGEATTRQYPATMHGAFLSGLREASRIL 595


                 ..
gi 270288740 461 NA 462
Cdd:PLN02529 596 HV 597
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 10-53 6.53e-11

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 64.11  E-value: 6.53e-11
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 270288740  10 AGHMFDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGG----RTY 53
Cdd:COG2072    3 ATEHVDVVVIGAGQAGLAAAYHLRRAGIDFVVLEKADDVGGtwrdNRY 50
COG3380 COG3380
Predicted NAD/FAD-dependent oxidoreductase [General function prediction only];
12-70 9.81e-11

Predicted NAD/FAD-dependent oxidoreductase [General function prediction only];


Pssm-ID: 442607 [Multi-domain]  Cd Length: 331  Bit Score: 62.97  E-value: 9.81e-11
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 270288740  12 HMFDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVkWVDVGGAYV 70
Cdd:COG3380    2 SMPDIAIIGAGIAGLAAARALQDAGHEVTVFEKSRGVGGRMATRRLDGG-RFDHGAQYF 59
PLN03000 PLN03000
amine oxidase
 15-505 1.29e-10

amine oxidase


Pssm-ID: 178578 [Multi-domain]  Cd Length: 881  Bit Score: 64.27  E-value: 1.29e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740  15 DVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVR---NEHVKWVDVGGAYV-GPTQNRILRLSKELGIETYK 90
Cdd:PLN03000 186 SVVIVGAGLSGLAAARQLMRFGFKVTVLEGRKRPGGRVYTKKmeaNRVGAAADLGGSVLtGTLGNPLGIIARQLGSSLYK 265

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740  91 VNVNERLVQyVKGKtypfrgAFPPVWNPLAYLDYNNLW-------RTMDEMGKEIPVDAPWQARHAQEWDKMTMKDlIDK 163
Cdd:PLN03000 266 VRDKCPLYR-VDGK------PVDPDVDLKVEVAFNQLLdkasklrQLMGDVSMDVSLGAALETFRQVSGNDVATEE-MGL 337

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 164 ICWTKTAREFAylfvNINVTSephEVS-ALWflwyvrqcggtARIFSVTNGGQERKFVGGSGQVSEqimgLLGDKVKL-- 240
Cdd:PLN03000 338 FNWHLANLEYA----NAGLVS---KLSlAFW-----------DQDDPYDMGGDHCFLPGGNGRLVQ----ALAENVPIly 395

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 241 SSPVTYIDQTDDNIIVeTLNHEHYECKYVISAIP--PILTAKIHFKPELPPERNQLIQRLPMGAVIKCMVYYKEAFW--- 315
Cdd:PLN03000 396 EKTVQTIRYGSNGVKV-IAGNQVYEGDMVLCTVPlgVLKNGSIKFVPELPQRKLDCIKRLGFGLLNKVAMLFPYVFWstd 474

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 316 --------KKKDYCGCMIIEDEEAPIAitlddtkpdgSLPAIMGFILARKADRLAKLHKDIRKRKICELYAKVLGSQEAL 387
Cdd:PLN03000 475 ldtfghltEDPNYRGEFFLFYSYAPVA----------GGPLLIALVAGEAAHKFETMPPTDAVTRVLHILRGIYEPQGIN 544

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 388 YPVHYEE--KNWCEEQYSGGCYTAYFPPGIMTQYGrVIRQPV--GRIYFAGTETATQWSGYMEGAVEAGER-AAREVLNA 462
Cdd:PLN03000 545 VPDPLQTvcTRWGGDPFSLGSYSNVAVGASGDDYD-ILAESVgdGRLFFAGEATTRRYPATMHGAFVTGLReAANMAQSA 623

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 270288740 463 LGKVAKKDIWVEEPESKDVPAIEITHTFLERNL---------------PSVPGLLKIT 505
Cdd:PLN03000 624 KARGIRKRIDRNPSKNAHSCAILLADLFRDPDLefgsfaiifsrrnpdPKSPAILRVT 681
PLN02576 PLN02576
protoporphyrinogen oxidase
 10-62 1.39e-10

protoporphyrinogen oxidase


Pssm-ID: 215314 [Multi-domain]  Cd Length: 496  Bit Score: 63.49  E-value: 1.39e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 270288740  10 AGHMFDVVVIGGGISGLAAA-KLLSEYKINVLVLEARDRVGGRTYTVRNEHVKW 62
Cdd:PLN02576   9 AASSKDVAVVGAGVSGLAAAyALASKHGVNVLVTEARDRVGGNITSVSEDGFIW 62
LhgO COG0579
L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];
13-49 2.25e-08

L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];


Pssm-ID: 440344 [Multi-domain]  Cd Length: 418  Bit Score: 56.31  E-value: 2.25e-08
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 270288740  13 MFDVVVIGGGISGLAAAKLLSEY-KINVLVLEARDRVG 49
Cdd:COG0579    4 MYDVVIIGAGIVGLALARELSRYeDLKVLVLEKEDDVA 41
Ppro0129 COG2907
Predicted flavin-containing amine oxidase [General function prediction only];
18-88 3.31e-08

Predicted flavin-containing amine oxidase [General function prediction only];


Pssm-ID: 442151 [Multi-domain]  Cd Length: 423  Bit Score: 55.89  E-value: 3.31e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740  18 VIGGGISGLAAAKLLSEyKINVLVLEARDRVGGRTYTVRnehvkwVDVGGAYVG----------PTQNRILRLSKELGIE 87
Cdd:COG2907    8 VIGSGISGLTAAWLLSR-RHDVTLFEANDRLGGHTHTVD------VDLDGRTVPvdtgfivfneRTYPNLTALFAELGVP 80


                 .
gi 270288740  88 T 88
Cdd:COG2907   81 T 81
PRK11883 PRK11883
protoporphyrinogen oxidase; Reviewed
 16-107 3.76e-08

protoporphyrinogen oxidase; Reviewed


Pssm-ID: 237009 [Multi-domain]  Cd Length: 451  Bit Score: 55.63  E-value: 3.76e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740  16 VVVIGGGISGLAAAKLLSEYK--INVLVLEARDRVGGRTYTVRNEHVkWVDVGG-AYVGptqnR---ILRLSKELGIEty 89
Cdd:PRK11883   3 VAIIGGGITGLSAAYRLHKKGpdADITLLEASDRLGGKIQTVRKDGF-PIELGPeSFLA----RkpsAPALVKELGLE-- 75

                         90       100
                 ....*....|....*....|....*.
gi 270288740  90 kvnvnERLVQ--------YVKGKTYP 107
Cdd:PRK11883  76 -----DELVAnttgqsyiYVNGKLHP 96
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 15-83 5.07e-08

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 54.71  E-value: 5.07e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 270288740   15 DVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTyTVRNehVKWvdVGGAYVGPTQNRILRLSKE 83
Cdd:pfam01266   1 DVVVIGGGIVGLSTAYELARRGLSVTLLERGDDPGSGA-SGRN--AGL--IHPGLRYLEPSELARLALE 64
crtI_fam TIGR02734
phytoene desaturase; Phytoene is converted to lycopene by desaturation at four (two ...
 16-56 1.35e-07

phytoene desaturase; Phytoene is converted to lycopene by desaturation at four (two symmetrical pairs of) sites. This is achieved by two enzymes (crtP and crtQ) in cyanobacteria (Gloeobacter being an exception) and plants, but by a single enzyme in most other bacteria and in fungi. This single enzyme is called the bacterial-type phytoene desaturase, or CrtI. Most members of this family, part of the larger pfam01593, which also contains amino oxidases, are CrtI itself; it is likely that all members act on either phytoene or on related compounds such as dehydrosqualene, for carotenoid biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]


Pssm-ID: 274273 [Multi-domain]  Cd Length: 495  Bit Score: 54.21  E-value: 1.35e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 270288740   16 VVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVR 56
Cdd:TIGR02734   1 AVVIGAGFGGLALAIRLAAAGIPVTVVEQRDKPGGRAGVLE 41
PLN02976 PLN02976
amine oxidase
 16-66 2.31e-07

amine oxidase


Pssm-ID: 215527 [Multi-domain]  Cd Length: 1713  Bit Score: 53.72  E-value: 2.31e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 270288740   16 VVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVKWVDVG 66
Cdd:PLN02976  696 IIVVGAGPAGLTAARHLQRQGFSVTVLEARSRIGGRVYTDRSSLSVPVDLG 746
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 12-55 6.82e-07

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 51.09  E-value: 6.82e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 270288740  12 HMFDVVVIGGGISGLAAAKLLSEYKINVLVLEARD--RVGGRTYTV 55
Cdd:COG0654    2 MRTDVLIVGGGPAGLALALALARAGIRVTVVERAPppRPDGRGIAL 47
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
12-90 1.29e-06

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 50.67  E-value: 1.29e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740  12 HMFDVVVIGGGISGLAAAKLLSEYKINVLVLEaRDRVGGRTyTVRNehvkwvdvGG----AYVGPTQNRILRLSKElGIE 87
Cdd:COG0665    1 ATADVVVIGGGIAGLSTAYHLARRGLDVTVLE-RGRPGSGA-SGRN--------AGqlrpGLAALADRALVRLARE-ALD 69


                 ...
gi 270288740  88 TYK 90
Cdd:COG0665   70 LWR 72
PLN02612 PLN02612
phytoene desaturase
 16-97 1.09e-05

phytoene desaturase


Pssm-ID: 215330 [Multi-domain]  Cd Length: 567  Bit Score: 47.91  E-value: 1.09e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740  16 VVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVKWVDVG-----GAYVGpTQNrilrLSKELGIetyk 90
Cdd:PLN02612  96 VVIAGAGLAGLSTAKYLADAGHKPILLEARDVLGGKVAAWKDEDGDWYETGlhiffGAYPN-VQN----LFGELGI---- 166


                 ....*..
gi 270288740  91 vnvNERL 97
Cdd:PLN02612 167 ---NDRL 170
SdhA COG1053
Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and ...
 12-50 2.06e-05

Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and conversion]; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit is part of the Pathway/BioSystem: TCA cycle


Pssm-ID: 440673 [Multi-domain]  Cd Length: 443  Bit Score: 47.14  E-value: 2.06e-05
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 270288740  12 HMFDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGG 50
Cdd:COG1053    2 HEYDVVVVGSGGAGLRAALEAAEAGLKVLVLEKVPPRGG 40
PRK07208 PRK07208
hypothetical protein; Provisional
 12-67 2.08e-05

hypothetical protein; Provisional


Pssm-ID: 235967 [Multi-domain]  Cd Length: 479  Bit Score: 47.19  E-value: 2.08e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 270288740  12 HMFDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVKwVDVGG 67
Cdd:PRK07208   3 NKKSVVIIGAGPAGLTAAYELLKRGYPVTVLEADPVVGGISRTVTYKGNR-FDIGG 57
mhpA PRK06183
bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;
1-48 4.36e-05

bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;


Pssm-ID: 235727 [Multi-domain]  Cd Length: 500  Bit Score: 46.05  E-value: 4.36e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 270288740   1 MTDlekPNLAGHMFDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRV 48
Cdd:PRK06183   1 MAA---QHPDAHDTDVVIVGAGPVGLTLANLLGQYGVRVLVLERWPTL 45
PRK08274 PRK08274
FAD-dependent tricarballylate dehydrogenase TcuA;
12-57 7.82e-05

FAD-dependent tricarballylate dehydrogenase TcuA;


Pssm-ID: 236214 [Multi-domain]  Cd Length: 466  Bit Score: 45.25  E-value: 7.82e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 270288740  12 HMFDVVVIGGGISGLAAAKLLSEYKINVLVLEA--RDRVGGRTYTVRN 57
Cdd:PRK08274   3 SMVDVLVIGGGNAALCAALAAREAGASVLLLEAapREWRGGNSRHTRN 50
Lpd COG1249
Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex ...
 12-50 1.21e-04

Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase [Energy production and conversion]; Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase is part of the Pathway/BioSystem: Glycine cleavagePyruvate oxidation


Pssm-ID: 440861 [Multi-domain]  Cd Length: 456  Bit Score: 44.69  E-value: 1.21e-04
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 270288740  12 HMFDVVVIGGGISGLAAAKLLSEYKINVLVLEaRDRVGG 50
Cdd:COG1249    2 KDYDLVVIGAGPGGYVAAIRAAQLGLKVALVE-KGRLGG 39
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
14-51 2.11e-04

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 43.18  E-value: 2.11e-04
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 270288740  14 FDVVVIGGGISGLAAAKLLSEYKINVLVLEaRDRVGGR 51
Cdd:COG0492    1 YDVVIIGAGPAGLTAAIYAARAGLKTLVIE-GGEPGGQ 37
MurD COG0771
UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell wall/membrane/envelope biogenesis]; ...
 16-63 2.99e-04

UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramoylalanine-D-glutamate ligase is part of the Pathway/BioSystem: Mureine biosynthesis


Pssm-ID: 440534 [Multi-domain]  Cd Length: 445  Bit Score: 43.15  E-value: 2.99e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 270288740  16 VVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVKWV 63
Cdd:COG0771    7 VLVLGLGKSGLAAARLLAKLGAEVTVSDDRPAPELAAAELEAPGVEVV 54
PLN02568 PLN02568
polyamine oxidase
 16-54 3.02e-04

polyamine oxidase


Pssm-ID: 215308 [Multi-domain]  Cd Length: 539  Bit Score: 43.28  E-value: 3.02e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 270288740  16 VVVIGGGISGLAAA-KLLSEYKIN----VLVLEARDRVGGRTYT 54
Cdd:PLN02568   8 IVIIGAGMAGLTAAnKLYTSSAANdmfeLTVVEGGDRIGGRINT 51
BetA COG2303
Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General ...
 13-76 3.08e-04

Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General function prediction only]; Choline dehydrogenase or related flavoprotein is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 441878 [Multi-domain]  Cd Length: 531  Bit Score: 43.28  E-value: 3.08e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 270288740  13 MFDVVVIGGGISGLAAAKLLSEY-KINVLVLEArdrvGGRTytvRNEhvkWVDVGGAYVGPTQNR 76
Cdd:COG2303    4 EYDYVIVGAGSAGCVLANRLSEDaGLRVLLLEA----GGRD---DDP---LIRMPAGYAKLLGNP 58
PTZ00367 PTZ00367
squalene epoxidase; Provisional
 6-46 3.20e-04

squalene epoxidase; Provisional


Pssm-ID: 240384 [Multi-domain]  Cd Length: 567  Bit Score: 43.30  E-value: 3.20e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 270288740   6 KPNLAGHMFDVVVIGGGISGLAAAKLLSEYKINVLVLEaRD 46
Cdd:PTZ00367  26 KPARTNYDYDVIIVGGSIAGPVLAKALSKQGRKVLMLE-RD 65
NadB COG0029
Aspartate oxidase [Coenzyme transport and metabolism]; Aspartate oxidase is part of the ...
 12-42 3.21e-04

Aspartate oxidase [Coenzyme transport and metabolism]; Aspartate oxidase is part of the Pathway/BioSystem: NAD biosynthesis


Pssm-ID: 439800 [Multi-domain]  Cd Length: 521  Bit Score: 43.17  E-value: 3.21e-04
                         10        20        30
                 ....*....|....*....|....*....|.
gi 270288740  12 HMFDVVVIGGGISGLAAAKLLSEYKiNVLVL 42
Cdd:COG0029    3 LKTDVLVIGSGIAGLSAALKLAERG-RVTLL 32
PRK12416 PRK12416
protoporphyrinogen oxidase; Provisional
 13-294 3.63e-04

protoporphyrinogen oxidase; Provisional


Pssm-ID: 183516  Cd Length: 463  Bit Score: 42.89  E-value: 3.63e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740  13 MFDVVVIGGGISGLAA----AKLLSEYKI--NVLVLEARDRVGGRTYTVRnEHVKWVDVGGAYVGPTQNRILRLSKELGI 86
Cdd:PRK12416   1 MKTVVVIGGGITGLSTmfylEKLKKDYNIdlNLILVEKEEYLGGKIHSVE-EKDFIMESGADSIVARNEHVMPLVKDLNL 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740  87 EtykvnvnERLVQYVKGKTYPFRgafppvwnplayldynnlwrtmDEMGKEIPVDA----PWQARH-------AQEWDKM 155
Cdd:PRK12416  80 E-------EEMVYNETGISYIYS----------------------DNTLHPIPSDTifgiPMSVESlfsstlvSTKGKIV 130

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 156 TMKDLIDK-ICWTK--TAREFAYLFVNINV-------------TSEPHEV---SAL-WFLWYVRQCGGTARIFSVTN--- 212
Cdd:PRK12416 131 ALKDFITKnKEFTKdtSLALFLESFLGKELverqiapvlsgvySGKLNELtmaSTLpYLLDYKNKYGSIIKGFEENKkqf 210

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270288740 213 -GGQERKFVGGSGQVSEQIMGL---LGD-KVKLSSPVTYIDQTDDNIIVETLNHEHYECKYVISAIPPILTAKIHFKPEL 287
Cdd:PRK12416 211 qSAGNKKFVSFKGGLSTIIDRLeevLTEtVVKKGAVTTAVSKQGDRYEISFANHESIQADYVVLAAPHDIAETLLQSNEL 290


                 ....*..
gi 270288740 288 PPERNQL 294
Cdd:PRK12416 291 NEQFHTF 297
PRK12843 PRK12843
FAD-dependent oxidoreductase;
14-54 7.40e-04

FAD-dependent oxidoreductase;


Pssm-ID: 237225 [Multi-domain]  Cd Length: 578  Bit Score: 42.03  E-value: 7.40e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 270288740  14 FDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYT 54
Cdd:PRK12843  17 FDVIVIGAGAAGMSAALFAAIAGLKVLLVERTEYVGGTTAT 57
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
15-51 1.44e-03

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 41.38  E-value: 1.44e-03
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 270288740  15 DVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGR 51
Cdd:COG1148  142 RALVIGGGIAGMTAALELAEQGYEVYLVEKEPELGGR 178
FAD_oxidored pfam12831
FAD dependent oxidoreductase; This family of proteins contains FAD dependent oxidoreductases ...
 15-50 1.49e-03

FAD dependent oxidoreductase; This family of proteins contains FAD dependent oxidoreductases and related proteins.


Pssm-ID: 432816 [Multi-domain]  Cd Length: 420  Bit Score: 41.06  E-value: 1.49e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 270288740   15 DVVVIGGGISGLAAAkllseykI-------NVLVLEARDRVGG 50
Cdd:pfam12831   1 DVVVVGGGPAGVAAA-------IaaaragaKVLLVERRGFLGG 36
PRK08132 PRK08132
FAD-dependent oxidoreductase; Provisional
 16-49 1.50e-03

FAD-dependent oxidoreductase; Provisional


Pssm-ID: 236158 [Multi-domain]  Cd Length: 547  Bit Score: 41.01  E-value: 1.50e-03
                         10        20        30
                 ....*....|....*....|....*....|....
gi 270288740  16 VVVIGGGISGLAAAKLLSEYKINVLVLEARDRVG 49
Cdd:PRK08132  26 VVVVGAGPVGLALAIDLAQQGVPVVLLDDDDTLS 59
HI0933_like pfam03486
HI0933-like protein;
14-49 1.51e-03

HI0933-like protein;


Pssm-ID: 427330 [Multi-domain]  Cd Length: 406  Bit Score: 41.03  E-value: 1.51e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 270288740   14 FDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVG 49
Cdd:pfam03486   1 FDVIVIGGGAAGLMAAISAAKRGRRVLLIEKGKKLG 36
PRK05329 PRK05329
glycerol-3-phosphate dehydrogenase subunit GlpB;
13-42 2.76e-03

glycerol-3-phosphate dehydrogenase subunit GlpB;


Pssm-ID: 235412  Cd Length: 422  Bit Score: 40.22  E-value: 2.76e-03
                         10        20        30
                 ....*....|....*....|....*....|
gi 270288740  13 MFDVVVIGGGISGLAAAKLLSEYKINVLVL 42
Cdd:PRK05329   2 KFDVLVIGGGLAGLTAALAAAEAGKRVALV 31
PRK11749 PRK11749
dihydropyrimidine dehydrogenase subunit A; Provisional
 16-50 2.93e-03

dihydropyrimidine dehydrogenase subunit A; Provisional


Pssm-ID: 236967 [Multi-domain]  Cd Length: 457  Bit Score: 40.16  E-value: 2.93e-03
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 270288740  16 VVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGG 50
Cdd:PRK11749 143 VAVIGAGPAGLTAAHRLARKGYDVTIFEARDKAGG 177
PRK06847 PRK06847
hypothetical protein; Provisional
 15-86 3.08e-03

hypothetical protein; Provisional


Pssm-ID: 235874 [Multi-domain]  Cd Length: 375  Bit Score: 39.86  E-value: 3.08e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 270288740  15 DVVVIGGGISGLAAAKLLSEYKINVLVLEARDrvggrtytvrnehvKWvDVGGAyvGPT-QNRILRLSKELGI 86
Cdd:PRK06847   6 KVLIVGGGIGGLSAAIALRRAGIAVDLVEIDP--------------EW-RVYGA--GITlQGNALRALRELGV 61
FAD_binding_2 pfam00890
FAD binding domain; This family includes members that bind FAD. This family includes the ...
 15-52 3.52e-03

FAD binding domain; This family includes members that bind FAD. This family includes the flavoprotein subunits from succinate and fumarate dehydrogenase, aspartate oxidase and the alpha subunit of adenylylsulphate reductase.


Pssm-ID: 395718 [Multi-domain]  Cd Length: 398  Bit Score: 39.96  E-value: 3.52e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 270288740   15 DVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRT 52
Cdd:pfam00890   1 DVLVIGGGLAGLAAALAAAEAGLKVAVVEKGQPFGGAT 38
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 14-51 4.32e-03

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 39.22  E-value: 4.32e-03
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 270288740   14 FDVVVIGGGISGLAAAKLLSEYKINVLVLEA-RDRVGGR 51
Cdd:pfam07992   1 YDVVVIGGGPAGLAAALTLAQLGGKVTLIEDeGTCPYGG 39
GG-red-SF TIGR02032
geranylgeranyl reductase family; This model represents a subfamily which includes ...
 14-49 4.72e-03

geranylgeranyl reductase family; This model represents a subfamily which includes geranylgeranyl reductases involved in chlorophyll and bacteriochlorophyll biosynthesis as well as other related enzymes which may also act on geranylgeranyl groups or related substrates. [Biosynthesis of cofactors, prosthetic groups, and carriers, Chlorophyll and bacteriochlorphyll]


Pssm-ID: 273936 [Multi-domain]  Cd Length: 295  Bit Score: 39.22  E-value: 4.72e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 270288740   14 FDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVG 49
Cdd:TIGR02032   1 YDVVVVGAGPAGASAAYRLADKGLRVLLLEKKSFPR 36
PRK11728 PRK11728
L-2-hydroxyglutarate oxidase;
13-49 5.03e-03

L-2-hydroxyglutarate oxidase;


Pssm-ID: 183292 [Multi-domain]  Cd Length: 393  Bit Score: 39.42  E-value: 5.03e-03
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 270288740  13 MFDVVVIGGGISGLAAAK-LLSEY-KINVLVLEARDRVG 49
Cdd:PRK11728   2 MYDFVIIGGGIVGLSTAMqLQERYpGARIAVLEKESGPA 40
AlaDh_PNT_C smart01002
Alanine dehydrogenase/PNT, C-terminal domain; Alanine dehydrogenase catalyzes the ...
 16-70 5.85e-03

Alanine dehydrogenase/PNT, C-terminal domain; Alanine dehydrogenase catalyzes the NAD-dependent reversible reductive amination of pyruvate into alanine.


Pssm-ID: 214966 [Multi-domain]  Cd Length: 149  Bit Score: 37.49  E-value: 5.85e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 270288740    16 VVVIGGGISGLAAAKLLSEYKINVLVL--------EARDRVGGRTYTVR------NEHVKWVD--VGGAYV 70
Cdd:smart01002  23 VVVIGAGVVGLGAAATAKGLGAEVTVLdvrparlrQLESLLGARFTTLYsqaellEEAVKEADlvIGAVLI 93
PRK08163 PRK08163
3-hydroxybenzoate 6-monooxygenase;
16-49 7.80e-03

3-hydroxybenzoate 6-monooxygenase;


Pssm-ID: 181262 [Multi-domain]  Cd Length: 396  Bit Score: 38.86  E-value: 7.80e-03
                         10        20        30
                 ....*....|....*....|....*....|....
gi 270288740  16 VVVIGGGISGLAAAKLLSEYKINVLVLEARDRVG 49
Cdd:PRK08163   7 VLIVGGGIGGLAAALALARQGIKVKLLEQAAEIG 40
Pyr_redox pfam00070
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 16-48 8.95e-03

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 425450 [Multi-domain]  Cd Length: 80  Bit Score: 35.26  E-value: 8.95e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 270288740   16 VVVIGGGISGLAAAKLLSEYKINVLVLEARDRV 48
Cdd:pfam00070   2 VVVVGGGYIGLELAGALARLGSKVTVVERRDRL 34
FixC COG0644
Dehydrogenase (flavoprotein) [Energy production and conversion];
21-51 9.38e-03

Dehydrogenase (flavoprotein) [Energy production and conversion];


Pssm-ID: 440409 [Multi-domain]  Cd Length: 281  Bit Score: 38.02  E-value: 9.38e-03
                         10        20        30
                 ....*....|....*....|....*....|.
gi 270288740  21 GGISGLAAAKLLSEYKINVLVLEARDRVGGR 51
Cdd:COG0644    1 AGPAGSAAARRLARAGLSVLLLEKGSFPGDK 31
GlpB COG3075
Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism];
14-29 9.53e-03

Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism];


Pssm-ID: 442309  Cd Length: 415  Bit Score: 38.62  E-value: 9.53e-03
                         10
                 ....*....|....*.
gi 270288740  14 FDVVVIGGGISGLAAA 29
Cdd:COG3075    3 FDVVVIGGGLAGLTAA 18
PRK07608 PRK07608
UbiH/UbiF family hydroxylase;
10-45 9.81e-03

UbiH/UbiF family hydroxylase;


Pssm-ID: 181057 [Multi-domain]  Cd Length: 388  Bit Score: 38.40  E-value: 9.81e-03
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 270288740  10 AGHM-FDVVVIGGGISGLAAAKLLSEYKINVLVLEAR 45
Cdd:PRK07608   1 AYHMkFDVVVVGGGLVGASLALALAQSGLRVALLAPR 37
PRK05249 PRK05249
Si-specific NAD(P)(+) transhydrogenase;
14-50 9.82e-03

Si-specific NAD(P)(+) transhydrogenase;


Pssm-ID: 235373 [Multi-domain]  Cd Length: 461  Bit Score: 38.60  E-value: 9.82e-03
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 270288740  14 FDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGG 50
Cdd:PRK05249   6 YDLVVIGSGPAGEGAAMQAAKLGKRVAVIERYRNVGG 42
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 16-48 9.92e-03

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 38.07  E-value: 9.92e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 270288740   16 VVVIGGGISGLAAAKLLSEYKINVLVLEARDRV 48
Cdd:pfam07992 155 VVVVGGGYIGVELAAALAKLGKEVTLIEALDRL 187
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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