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Conserved domains on  [gi|16128454|ref|NP_415003|]
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DNA polymerase III subunit tau [Escherichia coli str. K-12 substr. MG1655]

Protein Classification

DNA polymerase III subunit gamma/tau( domain architecture ID 11483016)

DNA polymerase III subunit gamma/tau is part of the DNA polymerase III holoenzyme; gamma and tau subunits are isoforms and either one or both may be present in the holoenzyme; gamma interacts with the delta subunit to transfer the beta subunit on the DNA while tau serves as a scaffold to help in the dimerization of the core complex

EC:  2.7.7.7
Gene Ontology:  GO:0009360|GO:0030337|GO:0016887
PubMed:  12940977
SCOP:  8022167

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
1-643 0e+00

DNA polymerase III subunits gamma and tau; Validated


:

Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 1138.05  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCR 80
Cdd:PRK07994   1 MSYQVLARKWRPQTFAEVVGQEHVLTALANALDLGRLHHAYLFSGTRGVGKTTIARLLAKGLNCETGITATPCGECDNCR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   81 EIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
Cdd:PRK07994  81 EIEQGRFVDLIEIDAASRTKVEDTRELLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  161 KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAM 240
Cdd:PRK07994 161 KLPVTILSRCLQFHLKALDVEQIRQQLEHILQAEQIPFEPRALQLLARAADGSMRDALSLTDQAIASGNGQVTTDDVSAM 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  241 LGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIELRMRELARTI 320
Cdd:PRK07994 241 LGTLDDDQALSLLEALVEGDGERVMALINQLAERGPDWEGLLVELLELLHRIAMAQLLPAALDNDMADIELRLRELARTL 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  321 PPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRALAFHPRMPLPEPEVPRQSFAPVA----------PTAVMTPTQVP 390
Cdd:PRK07994 321 PPEDVQLYYQTLLIGRKDLPLAPDRRMGVEMTLLRMLAFHPAAPLPEPEVPPQSAAPAAsaqataaptaAVAPPQAPAVP 400
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  391 PQPQSAPQQAPTVPLPETTSQVLAARQQLQRVQGATKAKKSEPAAATRARPVnNAALERLASVtdrvqaRPVPSALEKAP 470
Cdd:PRK07994 401 PPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKAKKSEPAAASRARPV-NSALERLASV------RPAPSALEKAP 473
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  471 AKKEAYRWKATTPVMQQKEVVATPKALKKALEHEKTPELAAKLAAEAIERDPWAAQVSQLSLPKLVEQVALNAWKEE-SD 549
Cdd:PRK07994 474 AKKEAYRWKATNPVEVKKEPVATPKALKKALEHEKTPELAAKLAAEAIERDPWAALVSQLGLPGLVEQLALNAWKEEhDN 553
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  550 NAVCLHLRSSQRHLNNRGAQQKLAEALSMLKGSTVELTIVEDDNPAVRTPLEWRQAIYEEKLAQARESIIADNNIQTLRR 629
Cdd:PRK07994 554 GEVCLHLRPSQRHLNSPRAQQRLAEALSELLGRTVELTIEEDDNPAVETPLEWRQRIYEEKLAQAEESIIADPNIQTLRQ 633
                        650
                 ....*....|....
gi 16128454  630 FFDAELDEESIRPI 643
Cdd:PRK07994 634 FFDAELDEDSIRPI 647
 
Name Accession Description Interval E-value
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
1-643 0e+00

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 1138.05  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCR 80
Cdd:PRK07994   1 MSYQVLARKWRPQTFAEVVGQEHVLTALANALDLGRLHHAYLFSGTRGVGKTTIARLLAKGLNCETGITATPCGECDNCR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   81 EIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
Cdd:PRK07994  81 EIEQGRFVDLIEIDAASRTKVEDTRELLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  161 KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAM 240
Cdd:PRK07994 161 KLPVTILSRCLQFHLKALDVEQIRQQLEHILQAEQIPFEPRALQLLARAADGSMRDALSLTDQAIASGNGQVTTDDVSAM 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  241 LGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIELRMRELARTI 320
Cdd:PRK07994 241 LGTLDDDQALSLLEALVEGDGERVMALINQLAERGPDWEGLLVELLELLHRIAMAQLLPAALDNDMADIELRLRELARTL 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  321 PPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRALAFHPRMPLPEPEVPRQSFAPVA----------PTAVMTPTQVP 390
Cdd:PRK07994 321 PPEDVQLYYQTLLIGRKDLPLAPDRRMGVEMTLLRMLAFHPAAPLPEPEVPPQSAAPAAsaqataaptaAVAPPQAPAVP 400
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  391 PQPQSAPQQAPTVPLPETTSQVLAARQQLQRVQGATKAKKSEPAAATRARPVnNAALERLASVtdrvqaRPVPSALEKAP 470
Cdd:PRK07994 401 PPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKAKKSEPAAASRARPV-NSALERLASV------RPAPSALEKAP 473
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  471 AKKEAYRWKATTPVMQQKEVVATPKALKKALEHEKTPELAAKLAAEAIERDPWAAQVSQLSLPKLVEQVALNAWKEE-SD 549
Cdd:PRK07994 474 AKKEAYRWKATNPVEVKKEPVATPKALKKALEHEKTPELAAKLAAEAIERDPWAALVSQLGLPGLVEQLALNAWKEEhDN 553
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  550 NAVCLHLRSSQRHLNNRGAQQKLAEALSMLKGSTVELTIVEDDNPAVRTPLEWRQAIYEEKLAQARESIIADNNIQTLRR 629
Cdd:PRK07994 554 GEVCLHLRPSQRHLNSPRAQQRLAEALSELLGRTVELTIEEDDNPAVETPLEWRQRIYEEKLAQAEESIIADPNIQTLRQ 633
                        650
                 ....*....|....
gi 16128454  630 FFDAELDEESIRPI 643
Cdd:PRK07994 634 FFDAELDEDSIRPI 647
dnaX_nterm TIGR02397
DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ ...
3-357 2.18e-180

DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ 365 amino acids of the translation of the dnaX gene. The full-length product of the dnaX gene in the model bacterium E. coli is the DNA polymerase III tau subunit. A translational frameshift leads to early termination and a truncated protein subunit gamma, about 1/3 shorter than tau and present in roughly equal amounts. This frameshift mechanism is not necessarily universal for species with DNA polymerase III but appears conserved in the exterme thermophile Thermus thermophilis. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274111 [Multi-domain]  Cd Length: 355  Bit Score: 515.19  E-value: 2.18e-180
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454     3 YQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREI 82
Cdd:TIGR02397   1 YQVLARKYRPQTFEDVIGQEHIVQTLKNAIKNGRIAHAYLFSGPRGTGKTSIARIFAKALNCQNGPDGEPCNECESCKEI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    83 EQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKL 162
Cdd:TIGR02397  81 NSGSSLDVIEIDAASNNGVDDIREILDNVKYAPSSGKYKVYIIDEVHMLSKSAFNALLKTLEEPPEHVVFILATTEPHKI 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   163 PVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAMLG 242
Cdd:TIGR02397 161 PATILSRCQRFDFKRIPLEDIVERLKKILDKEGIKIEDEALELIARAADGSLRDALSLLDQLISFGNGKITYEDVNELLG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   243 TLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIELRMRELARTIPP 322
Cdd:TIGR02397 241 LVDDEKLIELLEAILNKDTAEALKILDEILESGVDPEKFLEDLIEILRDLLLIKKTPSNLLAVLESEQEFLKELALKLSL 320
                         330       340       350
                  ....*....|....*....|....*....|....*
gi 16128454   323 TDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRAL 357
Cdd:TIGR02397 321 EFLLRLLDILLEALKDLRFSNDPRIWLEMTLLRLL 355
DnaX COG2812
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
1-358 7.97e-167

DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];


Pssm-ID: 442061 [Multi-domain]  Cd Length: 340  Bit Score: 480.07  E-value: 7.97e-167
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   1 MSYQVlarkwrPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCR 80
Cdd:COG2812   1 MSYQV------PQTFDDVVGQEHVVRTLKNALASGRLAHAYLFTGPRGVGKTTLARILAKALNCENGPTGEPCGECESCR 74
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  81 EIEQGRFVDLIEIDA-ASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDP 159
Cdd:COG2812  75 AIAAGSHPDVIEIDAeASNIGVDDIRELIEKVSYAPVEGRYKVYIIDEAHMLTTEAFNALLKTLEEPPPHVVFILATTEP 154
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454 160 QKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIAsgdgqvstqavsa 239
Cdd:COG2812 155 QKLLPTILSRCQRFDFRRLPPEEIAEHLAKIAEREGIEIEPEALALIARAADGSMRDALSLLDQAIA------------- 221
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454 240 mLGTLD-DDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIELRMRELAR 318
Cdd:COG2812 222 -FGLLDrRELLLDLLEALLAGDVAALLALAEELAKRGRDLKRFLDDLLSLLRDLLLLKLGPDAELLVNEDERERLQELAR 300
                       330       340       350       360
                ....*....|....*....|....*....|....*....|
gi 16128454 319 TIPPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRALA 358
Cdd:COG2812 301 RLSPERLLRAIQILLEARRELERNVNPRLALEMLLLRLAR 340
DNA_pol3_tau_5 pfam12170
DNA polymerase III tau subunit V interacting with alpha; This domain family is found in ...
500-640 2.19e-67

DNA polymerase III tau subunit V interacting with alpha; This domain family is found in bacteria, and is approximately 140 amino acids in length. The family is found in association with pfam00004. Domains I-III are shared between the tau and the gamma subunits, while most of the DnaB-binding Domain IV and all of the alpha-interacting Domain V are unique to tau. The extreme C-terminal region of this domain 5 is the part which interacts with the alpha subunit of the DNA polymerase III holoenzyme.


Pssm-ID: 432380 [Multi-domain]  Cd Length: 142  Bit Score: 216.35  E-value: 2.19e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   500 ALEHEKTPELAAKLAAEAIERDPWAAQVSQLSLPKLVEQVALNAWKEE-SDNAVCLHLRSSQRHLNNRGAQQKLAEALSM 578
Cdd:pfam12170   1 ALEHEKTPELAAKLIEEALERDPWAALIERLGLPKLVQQLALNSVLEQqQDDQILLHLRSSQRHLNSDSAQKALAEALSE 80
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 16128454   579 LKGSTVELTIVEDDNPAVRTPLEWRQAIYEEKLAQARESIIADNNIQTLRRFFDAELDEESI 640
Cdd:pfam12170  81 LLGKPVELTITEGDDPEQKTPLEWRQAIYEEKLEQARQSLQADPNVQLLQQRFDAELDEDSI 142
HLD_clamp_pol_III_gamma_tau cd18137
helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit ...
178-242 3.54e-23

helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit gamma/tau is part of the DNA polymerase III holoenzyme. Gamma and tau subunits are isoforms, both containing the helical lid domain. Gamma interacts with the delta subunit to transfer the beta subunit on the DNA while tau serves as a scaffold to help in the dimerization of the core complex. Both are members of the clamp-loader clade of the AAA+ superfamily.


Pssm-ID: 350839 [Multi-domain]  Cd Length: 65  Bit Score: 92.95  E-value: 3.54e-23
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 16128454 178 LDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAMLG 242
Cdd:cd18137   1 ISVEDIVGRLAHILEKEGIEIEDEALELIARAAEGSMRDALSLLDQAIAFGGGRVTLDDVREMLG 65
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
38-175 2.31e-05

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 44.67  E-value: 2.31e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454     38 HHAYLFSGTRGVGKTSIARLLAKGLNCETGITATpcgvcDNCREIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPAR 117
Cdd:smart00382   2 GEVILIVGPPGSGKTTLARALARELGPPGGGVIY-----IDGEDILEEVLDQLLLIIVGGKKASGSGELRLRLALALARK 76
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 16128454    118 GRFKVYLIDEVHMLSRHSFNALL--------KTLEEPPEHVKFLLATTDPQKLPVTILSRCLQFHL 175
Cdd:smart00382  77 LKPDVLILDEITSLLDAEQEALLllleelrlLLLLKSEKNLTVILTTNDEKDLGPALLRRRFDRRI 142
 
Name Accession Description Interval E-value
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
1-643 0e+00

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 1138.05  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCR 80
Cdd:PRK07994   1 MSYQVLARKWRPQTFAEVVGQEHVLTALANALDLGRLHHAYLFSGTRGVGKTTIARLLAKGLNCETGITATPCGECDNCR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   81 EIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
Cdd:PRK07994  81 EIEQGRFVDLIEIDAASRTKVEDTRELLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  161 KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAM 240
Cdd:PRK07994 161 KLPVTILSRCLQFHLKALDVEQIRQQLEHILQAEQIPFEPRALQLLARAADGSMRDALSLTDQAIASGNGQVTTDDVSAM 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  241 LGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIELRMRELARTI 320
Cdd:PRK07994 241 LGTLDDDQALSLLEALVEGDGERVMALINQLAERGPDWEGLLVELLELLHRIAMAQLLPAALDNDMADIELRLRELARTL 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  321 PPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRALAFHPRMPLPEPEVPRQSFAPVA----------PTAVMTPTQVP 390
Cdd:PRK07994 321 PPEDVQLYYQTLLIGRKDLPLAPDRRMGVEMTLLRMLAFHPAAPLPEPEVPPQSAAPAAsaqataaptaAVAPPQAPAVP 400
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  391 PQPQSAPQQAPTVPLPETTSQVLAARQQLQRVQGATKAKKSEPAAATRARPVnNAALERLASVtdrvqaRPVPSALEKAP 470
Cdd:PRK07994 401 PPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKAKKSEPAAASRARPV-NSALERLASV------RPAPSALEKAP 473
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  471 AKKEAYRWKATTPVMQQKEVVATPKALKKALEHEKTPELAAKLAAEAIERDPWAAQVSQLSLPKLVEQVALNAWKEE-SD 549
Cdd:PRK07994 474 AKKEAYRWKATNPVEVKKEPVATPKALKKALEHEKTPELAAKLAAEAIERDPWAALVSQLGLPGLVEQLALNAWKEEhDN 553
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  550 NAVCLHLRSSQRHLNNRGAQQKLAEALSMLKGSTVELTIVEDDNPAVRTPLEWRQAIYEEKLAQARESIIADNNIQTLRR 629
Cdd:PRK07994 554 GEVCLHLRPSQRHLNSPRAQQRLAEALSELLGRTVELTIEEDDNPAVETPLEWRQRIYEEKLAQAEESIIADPNIQTLRQ 633
                        650
                 ....*....|....
gi 16128454  630 FFDAELDEESIRPI 643
Cdd:PRK07994 634 FFDAELDEDSIRPI 647
PRK14949 PRK14949
DNA polymerase III subunits gamma and tau; Provisional
1-464 0e+00

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237863 [Multi-domain]  Cd Length: 944  Bit Score: 570.13  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCR 80
Cdd:PRK14949   1 MSYQVLARKWRPATFEQMVGQSHVLHALTNALTQQRLHHAYLFTGTRGVGKTSLARLFAKGLNCEQGVTATPCGVCSSCV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   81 EIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
Cdd:PRK14949  81 EIAQGRFVDLIEVDAASRTKVDDTRELLDNVQYRPSRGRFKVYLIDEVHMLSRSSFNALLKTLEEPPEHVKFLLATTDPQ 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  161 KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAM 240
Cdd:PRK14949 161 KLPVTVLSRCLQFNLKSLTQDEIGTQLNHILTQEQLPFEAEALTLLAKAANGSMRDALSLTDQAIAFGGGQVMLTQVQTM 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  241 LGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALgnDMAAIELRMRELARTI 320
Cdd:PRK14949 241 LGSIDEQHVIALLKALTDADIGVLMQTCAQVLAFGADAQEVLRSLLELLHQITLTQFAPAAA--QQSLYSEQIRAFAEQL 318
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  321 PPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRALAFhprmplpEPEVPRQSFAPVAPTAVMTPTQVPPQPQSAPQQA 400
Cdd:PRK14949 319 SPEQVQLYYQILLTGRKDLPHAPDPKSGLEMALLRAVAF-------VPEKPVKRWQVDDPAEISLPEGQTPSALAAAVQA 391
                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 16128454  401 PTVPLPETTSQVLAARQQLQRVQGATKAKKSEPAAATRARPVNNAALERLASVTDRVQARPVPS 464
Cdd:PRK14949 392 PHANEPQFVNAAPAEKKTALTEQTTAQQQVQAANAEAVAEADASAEPADTVEQALDDESELLAA 455
PRK14969 PRK14969
DNA polymerase III subunits gamma and tau; Provisional
1-643 0e+00

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237873 [Multi-domain]  Cd Length: 527  Bit Score: 553.97  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCR 80
Cdd:PRK14969   1 MSYQVLARKWRPKSFSELVGQEHVVRALTNALEQQRLHHAYLFTGTRGVGKTTLARILAKSLNCETGVTATPCGVCSACL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   81 EIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
Cdd:PRK14969  81 EIDSGRFVDLIEVDAASNTQVDAMRELLDNAQYAPTRGRFKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPQ 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  161 KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAM 240
Cdd:PRK14969 161 KIPVTVLSRCLQFNLKQMPPPLIVSHLQHILEQENIPFDATALQLLARAAAGSMRDALSLLDQAIAYGGGTVNESEVRAM 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  241 LGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIElRMRELARTI 320
Cdd:PRK14969 241 LGAIDQDYLFALLEALLAQDGAALLAIADAMEERSLSFDAALQDLAALLHRLAIAQTVPDSIADDLPERD-RLLDLAKRL 319
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  321 PPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRALAFHPrmplpepevprQSFAPVAPTAvmtptqvppqpqsapqqa 400
Cdd:PRK14969 320 SPEDIQLYYQIALHGRRDLGLAPDEYAGFTMTLLRMLAFRP-----------SEQDSGAGRA------------------ 370
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  401 ptvplpettsqvlaarqqlqrvqgatkakksePAAATRARPvnnaalerlasvtdrvqARPVPSALEKAPAKkeayrwka 480
Cdd:PRK14969 371 --------------------------------PGAVPGVNR-----------------TRAVPTAAPAAPAA-------- 393
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  481 TTPVMQQKevvatpkalkkalehektpelaaklaaeaiERDPWAAQVSQLSLPKLVEQVALN-AWKEESDNAVCLHLRSS 559
Cdd:PRK14969 394 ATPSDRQS------------------------------FNGNWRALVDQLKLSGLARELAQNcELKSFSEDRIELRVPEA 443
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  560 QRHLNNRGAQQKLAEALSMLKGSTVELTIVEDDNPAVrTPLEWRQAIYEEKLAQARESIIADNNIQTLRRFFDAELDEES 639
Cdd:PRK14969 444 HKHLLDKPYQDKLQAALEQHFGRPVQLIFSLGGVSGN-TPAELVSREKAERQSQAESAIESDGFVQELIEDFDATLIPSS 522

                 ....
gi 16128454  640 IRPI 643
Cdd:PRK14969 523 IKPI 526
PRK14961 PRK14961
DNA polymerase III subunits gamma and tau; Provisional
1-362 0e+00

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184925 [Multi-domain]  Cd Length: 363  Bit Score: 531.69  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCR 80
Cdd:PRK14961   1 MNYQILARKWRPQYFRDIIGQKHIVTAISNGLSLGRIHHAWLLSGTRGVGKTTIARLLAKSLNCQNGITSNPCRKCIICK 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   81 EIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
Cdd:PRK14961  81 EIEKGLCLDLIEIDAASRTKVEEMREILDNIYYSPSKSRFKVYLIDEVHMLSRHSFNALLKTLEEPPQHIKFILATTDVE 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  161 KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAM 240
Cdd:PRK14961 161 KIPKTILSRCLQFKLKIISEEKIFNFLKYILIKESIDTDEYALKLIAYHAHGSMRDALNLLEHAINLGKGNINIKNVTDM 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  241 LGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPaaLGND---MAAIELRMRELA 317
Cdd:PRK14961 241 LGLLNEKQSFLLTDALLKKDSKKTMLLLNKISSIGIEWENILIEMLRFLHHISMSQSFP--KIWNtifIKNYKNQIQKIA 318
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*
gi 16128454  318 RTIPPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRALAFHPR 362
Cdd:PRK14961 319 QNNKKTNIQLCYQILLNGRKELKFAPDQKIGVEMTLLRAINAITK 363
dnaX_nterm TIGR02397
DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ ...
3-357 2.18e-180

DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ 365 amino acids of the translation of the dnaX gene. The full-length product of the dnaX gene in the model bacterium E. coli is the DNA polymerase III tau subunit. A translational frameshift leads to early termination and a truncated protein subunit gamma, about 1/3 shorter than tau and present in roughly equal amounts. This frameshift mechanism is not necessarily universal for species with DNA polymerase III but appears conserved in the exterme thermophile Thermus thermophilis. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274111 [Multi-domain]  Cd Length: 355  Bit Score: 515.19  E-value: 2.18e-180
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454     3 YQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREI 82
Cdd:TIGR02397   1 YQVLARKYRPQTFEDVIGQEHIVQTLKNAIKNGRIAHAYLFSGPRGTGKTSIARIFAKALNCQNGPDGEPCNECESCKEI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    83 EQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKL 162
Cdd:TIGR02397  81 NSGSSLDVIEIDAASNNGVDDIREILDNVKYAPSSGKYKVYIIDEVHMLSKSAFNALLKTLEEPPEHVVFILATTEPHKI 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   163 PVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAMLG 242
Cdd:TIGR02397 161 PATILSRCQRFDFKRIPLEDIVERLKKILDKEGIKIEDEALELIARAADGSLRDALSLLDQLISFGNGKITYEDVNELLG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   243 TLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIELRMRELARTIPP 322
Cdd:TIGR02397 241 LVDDEKLIELLEAILNKDTAEALKILDEILESGVDPEKFLEDLIEILRDLLLIKKTPSNLLAVLESEQEFLKELALKLSL 320
                         330       340       350
                  ....*....|....*....|....*....|....*
gi 16128454   323 TDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRAL 357
Cdd:TIGR02397 321 EFLLRLLDILLEALKDLRFSNDPRIWLEMTLLRLL 355
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
1-643 6.86e-174

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 508.49  E-value: 6.86e-174
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNC-----ETGITATPCGV 75
Cdd:PRK14951   1 MSYLVLARKYRPRSFSEMVGQEHVVQALTNALTQQRLHHAYLFTGTRGVGKTTVSRILAKSLNCqgpdgQGGITATPCGV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   76 CDNCREIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLA 155
Cdd:PRK14951  81 CQACRDIDSGRFVDYTELDAASNRGVDEVQQLLEQAVYKPVQGRFKVFMIDEVHMLTNTAFNAMLKTLEEPPEYLKFVLA 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  156 TTDPQKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQ 235
Cdd:PRK14951 161 TTDPQKVPVTVLSRCLQFNLRPMAPETVLEHLTQVLAAENVPAEPQALRLLARAARGSMRDALSLTDQAIAFGSGQLQEA 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  236 AVSAMLGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGNDM---AAIELR 312
Cdd:PRK14951 241 AVRQMLGSVDRSHVFRLIDALAQGDGRTVVETADELRLNGLSAASTLEEMAAVLQRMAVLQAVPQAAAAATdpeAAEVAR 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  313 mreLARTIPPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRALAFHPRMPLPEPEVPRQsfAPVAPTAVMTPTQvppq 392
Cdd:PRK14951 321 ---LAALMPADETQLLYSICLHGRAELGLAPDEYAALTMVLLRLLAFKPAAAAEAAAPAEK--KTPARPEAAAPAA---- 391
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  393 pqsapqqaptVPLPETTS-QVLAARQQLQRVQGATKAKKSEPAAATRARPVNNAALERLASvtdrvQARPVPSALEKAPA 471
Cdd:PRK14951 392 ----------APVAQAAAaPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAP-----AAVALAPAPPAQAA 456
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  472 KKEAYRWKATTPVMQQKEVVATPKALKKALEHEKTPelaaklaaeaiERDPWAAQVSQL----SLPKLVEQVALNAwKEE 547
Cdd:PRK14951 457 PETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPTE-----------EGDVWHATVQQLaaaeAITALARELALQS-ELV 524
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  548 SDNAVCLHLRSSQRHLNNRGAQQKLAEALSMLKGSTVELTI---VEDDNPAVRTplewrQAIYEEKLAQARESIIADNNI 624
Cdd:PRK14951 525 ARDGDQWLLRVERESLNQPGARERLRAALEAALGHAVRLEVevgAVTDSPARRN-----AAARAERQREAEEIIRNDPFV 599
                        650
                 ....*....|....*....
gi 16128454  625 QTLRRFFDAELDEESIRPI 643
Cdd:PRK14951 600 QQLMRDFGAKIVPGSIKPV 618
PRK08691 PRK08691
DNA polymerase III subunits gamma and tau; Validated
1-643 6.05e-167

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236333 [Multi-domain]  Cd Length: 709  Bit Score: 494.23  E-value: 6.05e-167
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCR 80
Cdd:PRK08691   1 MAYQVLARKWRPKTFADLVGQEHVVKALQNALDEGRLHHAYLLTGTRGVGKTTIARILAKSLNCENAQHGEPCGVCQSCT 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   81 EIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
Cdd:PRK08691  81 QIDAGRYVDLLEIDAASNTGIDNIREVLENAQYAPTAGKYKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  161 KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAM 240
Cdd:PRK08691 161 KVPVTVLSRCLQFVLRNMTAQQVADHLAHVLDSEKIAYEPPALQLLGRAAAGSMRDALSLLDQAIALGSGKVAENDVRQM 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  241 LGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIELRMReLARTI 320
Cdd:PRK08691 241 IGAVDKQYLYELLTGIINQDGAALLAKAQEMAACAVGFDNALGELAILLQQLALIQAVPSALAHDDPDSDILHR-LAQTI 319
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  321 PPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRALAFHP---------------RMPLPEPEVPRQSFAPVAP----- 380
Cdd:PRK08691 320 SGEQIQLYYQIAVHGKRDLSLAPDEYAGFMMTLLRMLAFAPlaaascdanavientELQSPSAQTAEKETAAKKPqprpe 399
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  381 -----TAVMTPTQVPPQPQSAPQQAPT------------VPLPETTSQVlAARQQLQRVQGATKAKKSEPAAATRARPVN 443
Cdd:PRK08691 400 aetaqTPVQTASAAAMPSEGKTAGPVSnqenndvppwedAPDEAQTAAG-TAQTSAKSIQTASEAETPPENQVSKNKAAD 478
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  444 NAALERLASVTDR--VQARPVPSALE------KAPAKKEAYRWKATT--PVMQQKEVV------ATPKALKKALEHEKTP 507
Cdd:PRK08691 479 NETDAPLSEVPSEnpIQATPNDEAVEtetfahEAPAEPFYGYGFPDNdcPPEDGAEIPppdwehAAPADTAGGGADEEAE 558
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  508 ELAAKLAAEAIERDP------WAAQVSQLSLPKLVEQVALN--AWKEESDNAVCLHLR--SSQRHLNNRGAQQKLAEALS 577
Cdd:PRK08691 559 AGGIGGNNTPSAPPPefstenWAAIVRHFARKLGAAQMPAQhsAWTEYHPDTGLMVLAmtAEARATADKKRLDKIRDTLA 638
                        650       660       670       680       690       700
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 16128454  578 MLKGSTVELTIVEDDNPAVR-TPLEWRQAIYEEKLAQARESIIADNNIQTLRRFFDAELDEESIRPI 643
Cdd:PRK08691 639 QAYGLQLTLQTQDWRDEAGReTPAMQDKRVQAEDRQKAQALLEADPAAQKILQAFGAQWQPESLELA 705
DnaX COG2812
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
1-358 7.97e-167

DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];


Pssm-ID: 442061 [Multi-domain]  Cd Length: 340  Bit Score: 480.07  E-value: 7.97e-167
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   1 MSYQVlarkwrPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCR 80
Cdd:COG2812   1 MSYQV------PQTFDDVVGQEHVVRTLKNALASGRLAHAYLFTGPRGVGKTTLARILAKALNCENGPTGEPCGECESCR 74
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  81 EIEQGRFVDLIEIDA-ASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDP 159
Cdd:COG2812  75 AIAAGSHPDVIEIDAeASNIGVDDIRELIEKVSYAPVEGRYKVYIIDEAHMLTTEAFNALLKTLEEPPPHVVFILATTEP 154
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454 160 QKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIAsgdgqvstqavsa 239
Cdd:COG2812 155 QKLLPTILSRCQRFDFRRLPPEEIAEHLAKIAEREGIEIEPEALALIARAADGSMRDALSLLDQAIA------------- 221
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454 240 mLGTLD-DDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIELRMRELAR 318
Cdd:COG2812 222 -FGLLDrRELLLDLLEALLAGDVAALLALAEELAKRGRDLKRFLDDLLSLLRDLLLLKLGPDAELLVNEDERERLQELAR 300
                       330       340       350       360
                ....*....|....*....|....*....|....*....|
gi 16128454 319 TIPPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRALA 358
Cdd:COG2812 301 RLSPERLLRAIQILLEARRELERNVNPRLALEMLLLRLAR 340
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
1-642 1.46e-162

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 482.45  E-value: 1.46e-162
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNC-----ETGITATPCGV 75
Cdd:PRK12323   1 MSYQVLARKWRPRDFTTLVGQEHVVRALTHALEQQRLHHAYLFTGTRGVGKTTLSRILAKSLNCtgadgEGGITAQPCGQ 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   76 CDNCREIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLA 155
Cdd:PRK12323  81 CRACTEIDAGRFVDYIEMDAASNRGVDEMAQLLDKAVYAPTAGRFKVYMIDEVHMLTNHAFNAMLKTLEEPPEHVKFILA 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  156 TTDPQKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQ 235
Cdd:PRK12323 161 TTDPQKIPVTVLSRCLQFNLKQMPPGHIVSHLDAILGEEGIAHEVNALRLLAQAAQGSMRDALSLTDQAIAYSAGNVSEE 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  236 AVSAMLGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIElRMRE 315
Cdd:PRK12323 241 AVRGMLGAIDQSYLVRLLDALAAEDGAALLAIADEMAGRSLSFAGALQDLASLLQKIALAQVVPAAVQDDWPEAD-DIRR 319
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  316 LARTIPPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRALAFHP-----------------RMPLPEPEVPRQSFAPV 378
Cdd:PRK12323 320 LAGRFDAQEVQLFYQIANLGRSELALAPDEYAGFTMTLLRMLAFRPgqsgggagpataaaapvAQPAPAAAAPAAAAPAP 399
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  379 APTAVMTPTQVPPQPQSAPQQAPTVPLPETTSQVLAARQQLQRVQGATKAKKSEPAAATRARPVNNAALERLASVTDRVQ 458
Cdd:PRK12323 400 AAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAA 479
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  459 ARPVPSALEKAPAKKEAYRW-----------------------KATTPVMQQKEVVATPKALKKALEHEKTPELAAKLAA 515
Cdd:PRK12323 480 PARAAPAAAPAPADDDPPPWeelppefaspapaqpdaapagwvAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEP 559
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  516 EAIERDP--------------WAAQVSQLSLPKLVEQVALNA-WKEESDNAVclHLRSSQRHLNNRGAQQKLAEALSMLK 580
Cdd:PRK12323 560 VVAPRPPrasasglpdmfdgdWPALAARLPVRGLAQQLARQSeLAGVEGDTV--RLRVPVPALAEAEVVERLQAALTEHF 637
                        650       660       670       680       690       700
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 16128454  581 GSTVELTIveDDNPAVRTPLEWRQAIYEEKLAQARESIIADNNIQTLRRFFDAELDEESIRP 642
Cdd:PRK12323 638 GQPVRVVC--EVGAVGATAAAVDAEERAERQRAAEDAIAADPFVQALVRDFGGQVVPGSIQP 697
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
1-507 7.72e-157

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 472.03  E-value: 7.72e-157
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCR 80
Cdd:PRK07003   1 MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   81 EIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
Cdd:PRK07003  81 EIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQ 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  161 KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAM 240
Cdd:PRK07003 161 KIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEERIAFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTETAVSGM 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  241 LGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGNDMA-AIELrmRELART 319
Cdd:PRK07003 241 LGALDQTYMVRLLDALAAGDGPEILAVADEMALRSLSFSTALQDLASLLHRIAWAQFAPASVLDEWPeAADL--RRFAEL 318
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  320 IPPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRALAFHPRMP-------LPEPEVPRQSFAPVAPTAVMTPTQVPPQ 392
Cdd:PRK07003 319 LSPEQVQLFYQIATVGRGELGLAPDEYAGFTMTLLRMLAFEPAVTgggapggGVPARVAGAVPAPGARAAAAVGASAVPA 398
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  393 PQSAPQQAPTVPLPETTSQVLAAR-----QQLQRVQGATKAKKS--EPAAATRARPVNNAALERLASVTDRVQARPVPSA 465
Cdd:PRK07003 399 VTAVTGAAGAALAPKAAAAAAATRaeappAAPAPPATADRGDDAadGDAPVPAKANARASADSRCDERDAQPPADSGSAS 478
                        490       500       510       520
                 ....*....|....*....|....*....|....*....|..
gi 16128454  466 lEKAPAKKEAYRWKATTPVMQQKEVVATPKALKKALEHEKTP 507
Cdd:PRK07003 479 -APASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASRE 519
PRK05563 PRK05563
DNA polymerase III subunits gamma and tau; Validated
1-355 2.43e-146

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235505 [Multi-domain]  Cd Length: 559  Bit Score: 435.84  E-value: 2.43e-146
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCR 80
Cdd:PRK05563   1 MMYQALYRKWRPQTFEDVVGQEHITKTLKNAIKQGKISHAYLFSGPRGTGKTSAAKIFAKAVNCLNPPDGEPCNECEICK 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   81 EIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
Cdd:PRK05563  81 AITNGSLMDVIEIDAASNNGVDEIRDIRDKVKYAPSEAKYKVYIIDEVHMLSTGAFNALLKTLEEPPAHVIFILATTEPH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  161 KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAM 240
Cdd:PRK05563 161 KIPATILSRCQRFDFKRISVEDIVERLKYILDKEGIEYEDEALRLIARAAEGGMRDALSILDQAISFGDGKVTYEDALEV 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  241 LGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIEL-RMRELART 319
Cdd:PRK05563 241 TGSVSQEALDDLVDAIVEGDVAKALKILEELLDEGKDPNRFIEDLIYYLRDLLLVKTSPELEILDESTENDeLFKELSEK 320
                        330       340       350
                 ....*....|....*....|....*....|....*.
gi 16128454  320 IPPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLR 355
Cdd:PRK05563 321 LDIERLYRMIDILNDAQQQIKWTNQPRIYLEVALVK 356
PRK14960 PRK14960
DNA polymerase III subunit gamma/tau;
3-408 4.51e-146

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237868 [Multi-domain]  Cd Length: 702  Bit Score: 440.25  E-value: 4.51e-146
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    3 YQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREI 82
Cdd:PRK14960   2 YQVLARKYRPRNFNELVGQNHVSRALSSALERGRLHHAYLFTGTRGVGKTTIARILAKCLNCETGVTSTPCEVCATCKAV 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   83 EQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKL 162
Cdd:PRK14960  82 NEGRFIDLIEIDAASRTKVEDTRELLDNVPYAPTQGRFKVYLIDEVHMLSTHSFNALLKTLEEPPEHVKFLFATTDPQKL 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  163 PVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAMLG 242
Cdd:PRK14960 162 PITVISRCLQFTLRPLAVDEITKHLGAILEKEQIAADQDAIWQIAESAQGSLRDALSLTDQAIAYGQGAVHHQDVKEMLG 241
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  243 TLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIELRMRELARTIPP 322
Cdd:PRK14960 242 LIDRTIIYDLILAVHQNQREKVSQLLLQFRYQALDVSLVLDQLISTLHELALLQYLPELGLKYSEEINAKILQLSKLISA 321
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  323 TDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRALAFHPRMP----LPEPEVPR-----------QSFAPVAPTAVMTPT 387
Cdd:PRK14960 322 QDLQLYYQIACKGRSDLQLAVTQEQGFEMCVLRLLAFRPLAPneilVSEPVQQNgqaevglnsqaQTAQEITPVSAVQPV 401
                        410       420
                 ....*....|....*....|.
gi 16128454  388 QVPPQPQSAPQQAPTVPLPET 408
Cdd:PRK14960 402 EVISQPAMVEPEPEPEPEPEP 422
PRK14958 PRK14958
DNA polymerase III subunits gamma and tau; Provisional
1-387 6.17e-136

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184922 [Multi-domain]  Cd Length: 509  Bit Score: 407.58  E-value: 6.17e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCR 80
Cdd:PRK14958   1 MAHQVLARKWRPRCFQEVIGQAPVVRALSNALDQQYLHHAYLFTGTRGVGKTTISRILAKCLNCEKGVSANPCNDCENCR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   81 EIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
Cdd:PRK14958  81 EIDEGRFPDLFEVDAASRTKVEDTRELLDNIPYAPTKGRFKVYLIDEVHMLSGHSFNALLKTLEEPPSHVKFILATTDHH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  161 KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAM 240
Cdd:PRK14958 161 KLPVTVLSRCLQFHLAQLPPLQIAAHCQHLLKEENVEFENAALDLLARAANGSVRDALSLLDQSIAYGNGKVLIADVKTM 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  241 LGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGNDMAAielRMRELARTI 320
Cdd:PRK14958 241 LGTIEPLLLFDILEALAAKAGDRLLGCVTRLVEQGVDFSNALADLLSLLHQIAIIQTVPEALIENDSE---QLRQLAKLL 317
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 16128454  321 PPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRALAFHPRMPLPEPEVPRQSfapvaptAVMTPT 387
Cdd:PRK14958 318 DREDVQLFYQIGLIGQRDLAYSPTPQTGFEMTLLRMLAFYPSAANAIPETESKE-------AVVTPT 377
PRK09111 PRK09111
DNA polymerase III subunits gamma and tau; Validated
3-460 2.05e-129

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236382 [Multi-domain]  Cd Length: 598  Bit Score: 393.88  E-value: 2.05e-129
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    3 YQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCET-----GITATPCGVCD 77
Cdd:PRK09111  11 YRVLARKYRPQTFDDLIGQEAMVRTLTNAFETGRIAQAFMLTGVRGVGKTTTARILARALNYEGpdgdgGPTIDLCGVGE 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   78 NCREIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATT 157
Cdd:PRK09111  91 HCQAIMEGRHVDVLEMDAASHTGVDDIREIIESVRYRPVSARYKVYIIDEVHMLSTAAFNALLKTLEEPPPHVKFIFATT 170
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  158 DPQKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAV 237
Cdd:PRK09111 171 EIRKVPVTVLSRCQRFDLRRIEADVLAAHLSRIAAKEGVEVEDEALALIARAAEGSVRDGLSLLDQAIAHGAGEVTAEAV 250
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  238 SAMLGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGN-DMAAIE-LRMRE 315
Cdd:PRK09111 251 RDMLGLADRARVIDLFEALMRGDVAAALAEFRAQYDAGADPVVVLTDLAEFTHLVTRLKIVPDAAEDpSLSEAErTRGAE 330
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  316 LARTIPPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRaLAFHPRMPLPEPEVPRQSFAPVAPTAVMTPTQVPPQPQS 395
Cdd:PRK09111 331 FAKKLSMRVLSRLWQMLLKGIEEVQGAPRPLAAAEMVLIR-LAYAADLPTPDEALRRLQEGPPSPGGGGGGPPGGGGAPG 409
                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 16128454  396 APQQAPTVPLPETTSQVLAARQQLQRVQGATKAkkSEPAAATRARPVNNAALERLASVTDRVQAR 460
Cdd:PRK09111 410 APAAAAAPGAAAAAPAAGGPAAALAAVPDAAAA--AAAPPAPAAAPQPAVRLNSFEDIVALAEEK 472
PRK14965 PRK14965
DNA polymerase III subunits gamma and tau; Provisional
1-462 8.57e-124

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237871 [Multi-domain]  Cd Length: 576  Bit Score: 378.70  E-value: 8.57e-124
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCR 80
Cdd:PRK14965   1 MSYLVLARKYRPQTFSDLTGQEHVSRTLQNAIDTGRVAHAFLFTGARGVGKTSTARILAKALNCEQGLTAEPCNVCPPCV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   81 EIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
Cdd:PRK14965  81 EITEGRSVDVFEIDGASNTGVDDIRELRENVKYLPSRSRYKIFIIDEVHMLSTNAFNALLKTLEEPPPHVKFIFATTEPH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  161 KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAM 240
Cdd:PRK14965 161 KVPITILSRCQRFDFRRIPLQKIVDRLRYIADQEGISISDAALALVARKGDGSMRDSLSTLDQVLAFCGDAVGDDDVAEL 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  241 LGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQL--SPAALgNDMAAIEL-RMRELA 317
Cdd:PRK14965 241 LGVVDRRLLLDISAAVFGRDTRALLEIVERVDEFGYNMRQFCQELIDHLRNLVVLRAvgEPGDL-LDLSEAELaELRAQA 319
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  318 RTIPPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRALAFHPRMPLPEpEVPR----QSFAPVAPTAVMTPTQVPPQP 393
Cdd:PRK14965 320 AAADAADLQRHLTLLLRAEGEMAHASFPRLVLEMALLKMATLAPGAPVSE-LLDRlealERGAPAPPSAAWGAPTPAAPA 398
                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  394 QSAPQQAPTVPLPetTSQVLAARQQLQRVQGATKAKKSEPAAATRARPvnnAALERLASVTDRVQ-ARPV 462
Cdd:PRK14965 399 APPPAAAPPVPPA--APARPAAARPAPAPAPPAAAAPPARSADPAAAA---SAGDRWRAFVAFVKgKKPA 463
PRK14957 PRK14957
DNA polymerase III subunits gamma and tau; Provisional
1-362 3.36e-121

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184921 [Multi-domain]  Cd Length: 546  Bit Score: 370.95  E-value: 3.36e-121
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCR 80
Cdd:PRK14957   1 MSYQALARKYRPQSFAEVAGQQHALNSLVHALETQKVHHAYLFTGTRGVGKTTLGRLLAKCLNCKTGVTAEPCNKCENCV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   81 EIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
Cdd:PRK14957  81 AINNNSFIDLIEIDAASRTGVEETKEILDNIQYMPSQGRYKVYLIDEVHMLSKQSFNALLKTLEEPPEYVKFILATTDYH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  161 KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAM 240
Cdd:PRK14957 161 KIPVTILSRCIQLHLKHISQADIKDQLKIILAKENINSDEQSLEYIAYHAKGSLRDALSLLDQAISFCGGELKQAQIKQM 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  241 LGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIELRMRELARtI 320
Cdd:PRK14957 241 LGIIDSEEVYSIINAIIDNDPKAILPAIKNLALTESSADAVLDRIAEIWFACCIYSFTQSLDAVNDIDVDIINNILAK-I 319
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|..
gi 16128454  321 PPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRALAFHPR 362
Cdd:PRK14957 320 SIEQAHFLYQLTITAKKDIALAPNFETGVTMAILRLIAFQKK 361
PRK14953 PRK14953
DNA polymerase III subunits gamma and tau; Provisional
1-294 8.08e-111

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237867 [Multi-domain]  Cd Length: 486  Bit Score: 342.19  E-value: 8.08e-111
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCR 80
Cdd:PRK14953   1 MMYIPFARKYRPKFFKEVIGQEIVVRILKNAVKLQRVSHAYIFAGPRGTGKTTIARILAKVLNCLNPQEGEPCGKCENCV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   81 EIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
Cdd:PRK14953  81 EIDKGSFPDLIEIDAASNRGIDDIRALRDAVSYTPIKGKYKVYIIDEAHMLTKEAFNALLKTLEEPPPRTIFILCTTEYD 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  161 KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAM 240
Cdd:PRK14953 161 KIPPTILSRCQRFIFSKPTKEQIKEYLKRICNEEKIEYEEKALDLLAQASEGGMRDAASLLDQASTYGEGKVTIKVVEEF 240
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 16128454  241 LGTLDDDQALSLVEAMVEANGERVMALINEAAARGIE----WEALLVEMLGLLHRIAM 294
Cdd:PRK14953 241 LGIVSQESVRKFLNLLLESDVDEAIKFLRTLEEKGYNlnkfWKQLEEEIRNILLNKSL 298
PRK08451 PRK08451
DNA polymerase III subunits gamma and tau; Validated
4-289 1.30e-110

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236267 [Multi-domain]  Cd Length: 535  Bit Score: 343.17  E-value: 1.30e-110
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    4 QVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREIE 83
Cdd:PRK08451   2 QALALKYRPKHFDELIGQESVSKTLSLALDNNRLAHAYLFSGLRGSGKTSSARIFARALVCEQGPSSTPCDTCIQCQSAL 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   84 QGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLP 163
Cdd:PRK08451  82 ENRHIDIIEMDAASNRGIDDIRELIEQTKYKPSMARFKIFIIDEVHMLTKEAFNALLKTLEEPPSYVKFILATTDPLKLP 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  164 VTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAMLGT 243
Cdd:PRK08451 162 ATILSRTQHFRFKQIPQNSIISHLKTILEKEGVSYEPEALEILARSGNGSLRDTLTLLDQAIIYCKNAITESKVADMLGL 241
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 16128454  244 LDDDQALSLVEAMVEANGERVMALINEaaARGIEWEALLVEMLGLL 289
Cdd:PRK08451 242 LDPSKLEDFFQAILNQDKEKLFELLKE--LEDYEAEMVLDEMMLFL 285
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
1-472 3.02e-102

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 322.91  E-value: 3.02e-102
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGI-TATPCGVCDNC 79
Cdd:PRK14950   1 MTVQVLYRKWRSQTFAELVGQEHVVQTLRNAIAEGRVAHAYLFTGPRGVGKTSTARILAKAVNCTTNDpKGRPCGTCEMC 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   80 REIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDP 159
Cdd:PRK14950  81 RAIAEGSAVDVIEMDAASHTSVDDAREIIERVQFRPALARYKVYIIDEVHMLSTAAFNALLKTLEEPPPHAIFILATTEV 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  160 QKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSA 239
Cdd:PRK14950 161 HKVPATILSRCQRFDFHRHSVADMAAHLRKIAAAEGINLEPGALEAIARAATGSMRDAENLLQQLATTYGGEISLSQVQS 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  240 MLGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIELR-MRELAR 318
Cdd:PRK14950 241 LLGISGDEEVKALAEALLAKDLKAALRTLNAVAADGADLRQFTRDLVEYLRQVMLLNSGADRSLLDLTADEKAaLQKVSQ 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  319 TIPPTDI--------QLYYQtlligrkeLPYAPDRRMGVEMTLLRALAFHPRMPLP-EPEVPRQSFAPVAPTAVMTPTQV 389
Cdd:PRK14950 321 IANLEALtkwvkafsQLDFQ--------LRTTSYGQLPLELAVIEALLVPVPAPQPaKPTAAAPSPVRPTPAPSTRPKAA 392
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  390 PPQPQSAPQQAPTVPLPETTSQVLAA--------------RQQLQRVQGATKAKKSEPAAATRARPVNNAALERL----A 451
Cdd:PRK14950 393 AAANIPPKEPVRETATPPPVPPRPVAppvphtpesapkltRAAIPVDEKPKYTPPAPPKEEEKALIADGDVLEQLeaiwK 472
                        490       500
                 ....*....|....*....|..
gi 16128454  452 SVTDRVQAR-PVPSALEKAPAK 472
Cdd:PRK14950 473 QILRDVPPRsPAVQALLSSGVR 494
PRK06647 PRK06647
DNA polymerase III subunits gamma and tau; Validated
1-357 8.94e-99

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235845 [Multi-domain]  Cd Length: 563  Bit Score: 313.25  E-value: 8.94e-99
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCR 80
Cdd:PRK06647   1 MSYRGTATKRRPRDFNSLEGQDFVVETLKHSIESNKIANAYIFSGPRGVGKTSSARAFARCLNCVNGPTPMPCGECSSCK 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   81 EIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
Cdd:PRK06647  81 SIDNDNSLDVIEIDGASNTSVQDVRQIKEEIMFPPASSRYRVYIIDEVHMLSNSAFNALLKTIEEPPPYIVFIFATTEVH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  161 KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAM 240
Cdd:PRK06647 161 KLPATIKSRCQHFNFRLLSLEKIYNMLKKVCLEDQIKYEDEALKWIAYKSTGSVRDAYTLFDQVVSFSDSDITLEQIRSK 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  241 LGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLV-------EMLGLLHRI---AMVQLSPAALGNDMAAIE 310
Cdd:PRK06647 241 MGLTGDEFLEKLASSILNEDAKELLCVLDSVFLSGVSVEQFLLdcieffrELLFLKHGIkneAFIGIKAERLPEKLREFD 320
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*..
gi 16128454  311 LRMRELArtipptdIQLYYQTLligrKELPYAPDRRMGVEMTLLRAL 357
Cdd:PRK06647 321 LSQIERA-------ISVLLETY----RDLQFSVNPRYELEINFSKIL 356
PRK14955 PRK14955
DNA polymerase III subunits gamma and tau; Provisional
1-374 3.55e-97

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184919 [Multi-domain]  Cd Length: 397  Bit Score: 303.74  E-value: 3.55e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGI--------TATP 72
Cdd:PRK14955   1 MSYQVIARKYRPKKFADITAQEHITRTIQNSLRMGRVGHGYIFSGLRGVGKTTAARVFAKAVNCQRMIddadylqeVTEP 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   73 CGVCDNCREIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKF 152
Cdd:PRK14955  81 CGECESCRDFDAGTSLNISEFDAASNNSVDDIRLLRENVRYGPQKGRYRVYIIDEVHMLSIAAFNAFLKTLEEPPPHAIF 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  153 LLATTDPQKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIA-----S 227
Cdd:PRK14955 161 IFATTELHKIPATIASRCQRFNFKRIPLEEIQQQLQGICEAEGISVDADALQLIGRKAQGSMRDAQSILDQVIAfsvesE 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  228 GDGQVSTQAVSAMLGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQ-LSPAALGNDM 306
Cdd:PRK14955 241 GEGSIRYDKVAELLNYIDDEHFFAVTDAVADGDAVAMLDVAQFVIRNGYDEQDFLEKLIEHLRNFLVVHnLRSTRLVERP 320
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 16128454  307 AAIELRMRELARTIPPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRALAFHPRMPLPEPEVPRQS 374
Cdd:PRK14955 321 DAVRERYERDAAKFSPEVIMQMTDLLLQTQKELKFQFEYQFRFELALLKLIEIGHPAPTAAAAPTGGA 388
PRK06305 PRK06305
DNA polymerase III subunits gamma and tau; Validated
2-291 1.26e-95

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 180523 [Multi-domain]  Cd Length: 451  Bit Score: 301.31  E-value: 1.26e-95
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    2 SYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNC-ETGITATPCGVCDNCR 80
Cdd:PRK06305   3 SYQVSSRKYRPQTFSEILGQDAVVAVLKNALRFNRAAHAYLFSGIRGTGKTTLARIFAKALNCqNPTEDQEPCNQCASCK 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   81 EIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
Cdd:PRK06305  83 EISSGTSLDVLEIDGASHRGIEDIRQINETVLFTPSKSRYKIYIIDEVHMLTKEAFNSLLKTLEEPPQHVKFFLATTEIH 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  161 KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAM 240
Cdd:PRK06305 163 KIPGTILSRCQKMHLKRIPEETIIDKLALIAKQEGIETSREALLPIARAAQGSLRDAESLYDYVVGLFPKSLDPDSVAKA 242
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|.
gi 16128454  241 LGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEwEALLVEMLGLLHR 291
Cdd:PRK06305 243 LGLLSQDSLYTLDEAITTQNYAQALEPVTDAMNSGVA-PAHFLHDLTLFFR 292
PRK07133 PRK07133
DNA polymerase III subunits gamma and tau; Validated
1-289 1.53e-94

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235943 [Multi-domain]  Cd Length: 725  Bit Score: 306.74  E-value: 1.53e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGIT-ATPCGVCdnc 79
Cdd:PRK07133   3 MKYKALYRKYRPKTFDDIVGQDHIVQTLKNIIKSNKISHAYLFSGPRGTGKTSVAKIFANALNCSHKTDlLEPCQEC--- 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   80 reIEQ-GRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTD 158
Cdd:PRK07133  80 --IENvNNSLDIIEMDAASNNGVDEIRELIENVKNLPTQSKYKIYIIDEVHMLSKSAFNALLKTLEEPPKHVIFILATTE 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  159 PQKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVS 238
Cdd:PRK07133 158 VHKIPLTILSRVQRFNFRRISEDEIVSRLEFILEKENISYEKNALKLIAKLSSGSLRDALSIAEQVSIFGNNKITLKNVE 237
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|.
gi 16128454  239 AMLGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLL 289
Cdd:PRK07133 238 ELFGLVSNENLINLLNLLYSKDIKEVLNILNQIKEQGIDPELLLISLINLV 288
PRK14948 PRK14948
DNA polymerase III subunit gamma/tau;
1-289 8.47e-93

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237862 [Multi-domain]  Cd Length: 620  Bit Score: 299.19  E-value: 8.47e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNC--ETGITATPCGVCDN 78
Cdd:PRK14948   1 MAYEPLHHKYRPQRFDELVGQEAIATTLKNALISNRIAPAYLFTGPRGTGKTSSARILAKSLNClnSDKPTPEPCGKCEL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   79 CREIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTD 158
Cdd:PRK14948  81 CRAIAAGNALDVIEIDAASNTGVDNIRELIERAQFAPVQARWKVYVIDECHMLSTAAFNALLKTLEEPPPRVVFVLATTD 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  159 PQKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQaIASGDGQVSTQAVS 238
Cdd:PRK14948 161 PQRVLPTIISRCQRFDFRRIPLEAMVQHLSEIAEKESIEIEPEALTLVAQRSQGGLRDAESLLDQ-LSLLPGPITPEAVW 239
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|.
gi 16128454  239 AMLGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLL 289
Cdd:PRK14948 240 DLLGAVPEQDLLNLLKALASNDPESLLDSCRQLLDRGREPLAILQGLAAFY 290
PRK14964 PRK14964
DNA polymerase III subunits gamma and tau; Provisional
6-367 1.65e-91

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237870 [Multi-domain]  Cd Length: 491  Bit Score: 292.07  E-value: 1.65e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    6 LARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREIEQG 85
Cdd:PRK14964   3 LALKYRPSSFKDLVGQDVLVRILRNAFTLNKIPQSILLVGASGVGKTTCARIISLCLNCSNGPTSDPCGTCHNCISIKNS 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   86 RFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVT 165
Cdd:PRK14964  83 NHPDVIEIDAASNTSVDDIKVILENSCYLPISSKFKVYIIDEVHMLSNSAFNALLKTLEEPAPHVKFILATTEVKKIPVT 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  166 ILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAMLGTLD 245
Cdd:PRK14964 163 IISRCQRFDLQKIPTDKLVEHLVDIAKKENIEHDEESLKLIAENSSGSMRNALFLLEQAAIYSNNKISEKSVRDLLGCVD 242
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  246 DDQALSLVEAMVEANGERVMALINEA--AARGIeweALLVEMLGLLHRIAMVQLSP---AALGNDmaaIELRMRELARTI 320
Cdd:PRK14964 243 KHILEDLVEAILLGDAQSALNVFRELcnTSNPV---IILEGMLQIIYEICYFSITKeidFLLGED---LITRIKSLKIGS 316
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*..
gi 16128454  321 PPTDIQLyYQTLLIGRKELPYAPDRRMGVEMTLLRaLAFHPRMPLPE 367
Cdd:PRK14964 317 TIFLSRL-WQMLLKGIQEVKSSTCVKQAAEMMIIR-LCYLSDLPSPQ 361
PRK14959 PRK14959
DNA polymerase III subunits gamma and tau; Provisional
1-446 1.68e-91

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184923 [Multi-domain]  Cd Length: 624  Bit Score: 296.21  E-value: 1.68e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCR 80
Cdd:PRK14959   1 MSHASLTARYRPQTFAEVAGQETVKAILSRAAQENRVAPAYLFSGTRGVGKTTIARIFAKALNCETAPTGEPCNTCEQCR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   81 EIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
Cdd:PRK14959  81 KVTQGMHVDVVEIDGASNRGIDDAKRLKEAIGYAPMEGRYKVFIIDEAHMLTREAFNALLKTLEEPPARVTFVLATTEPH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  161 KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAM 240
Cdd:PRK14959 161 KFPVTIVSRCQHFTFTRLSEAGLEAHLTKVLGREGVDYDPAAVRLIARRAAGSVRDSMSLLGQVLALGESRLTIDGARGV 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  241 LGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMV-QLSPAALGN-DMAAIELRM-RELA 317
Cdd:PRK14959 241 LGLAGQELFLRLMEALAAQDCLGVANVVRELLDRGVDMGFFLRELVATWRNLFMLrQAGEAALASlDLPEDEARQwLGWA 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  318 RTIPPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRaLAFHPRMplpepeVPRQSFAPVAPTAvmTPTQVPPQPQSAP 397
Cdd:PRK14959 321 KRFEPAHIHACWQMTLEGQRRVLTSLEPAMALELLLLN-LAMLPRL------MPVESLRPSGGGA--SAPSGSAAEGPAS 391
                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*....
gi 16128454  398 QQAPTVPLPETtsqvlaarqqlQRVQGATKAKKSEPAAATRARPVNNAA 446
Cdd:PRK14959 392 GGAATIPTPGT-----------QGPQGTAPAAGMTPSSAAPATPAPSAA 429
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
3-493 1.30e-88

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 288.21  E-value: 1.30e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    3 YQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETgITA--TPCGVCDNCR 80
Cdd:PRK14971   4 YIVSARKYRPSTFESVVGQEALTTTLKNAIATNKLAHAYLFCGPRGVGKTTCARIFAKTINCQN-LTAdgEACNECESCV 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   81 EIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
Cdd:PRK14971  83 AFNEQRSYNIHELDAASNNSVDDIRNLIEQVRIPPQIGKYKIYIIDEVHMLSQAAFNAFLKTLEEPPSYAIFILATTEKH 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  161 KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAM 240
Cdd:PRK14971 163 KILPTILSRCQIFDFNRIQVADIVNHLQYVASKEGITAEPEALNVIAQKADGGMRDALSIFDQVVSFTGGNITYKSVIEN 242
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  241 LGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLhRIAMVQLSPAALG--NDMAAIELRMRELAR 318
Cdd:PRK14971 243 LNILDYDYYFRLTDALLAGKVSDSLLLFDEILNKGFDGSHFITGLASHF-RDLLVCKDAATLQllEVGESIRQRYLEQAQ 321
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  319 TippTDIQLYYQTL-LIGRKELPY--APDRRMGVEMTLLRALAF-----------HPRMPLP----EPEVPRQSFAPVAP 380
Cdd:PRK14971 322 K---CPMSFLYRALkLCNQCDLNYraSKNKRLLVELTLIQLAQLtqkgddasggrGPKQHIKpvftQPAAAPQPSAAAAA 398
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  381 TAVMTPTQVPPQPQSAPQQAPTVPLPETTSQVLAARQQLQRVQGATKAKKSEPAAATR----------ARPVNNAALERL 450
Cdd:PRK14971 399 SPSPSQSSAAAQPSAPQSATQPAGTPPTVSVDPPAAVPVNPPSTAPQAVRPAQFKEEKkipvskvsslGPSTLRPIQEKA 478
                        490       500       510       520
                 ....*....|....*....|....*....|....*....|...
gi 16128454  451 ASVTDRVQARPVPSALEKAPAKKEAYRWKATTPVMQQKEVVAT 493
Cdd:PRK14971 479 EQATGNIKEAPTGTQKEIFTEEDLQYYWQEFAGTRPQEEKALK 521
PRK14962 PRK14962
DNA polymerase III subunits gamma and tau; Provisional
4-286 1.94e-88

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237869 [Multi-domain]  Cd Length: 472  Bit Score: 283.19  E-value: 1.94e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    4 QVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREIE 83
Cdd:PRK14962   2 EALYRKYRPKTFSEVVGQDHVKKLIINALKKNSISHAYIFAGPRGTGKTTVARILAKSLNCENRKGVEPCNECRACRSID 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   84 QGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLP 163
Cdd:PRK14962  82 EGTFMDVIELDAASNRGIDEIRKIRDAVGYRPMEGKYKVYIIDEVHMLTKEAFNALLKTLEEPPSHVVFVLATTNLEKVP 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  164 VTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAMLGT 243
Cdd:PRK14962 162 PTIISRCQVIEFRNISDELIIKRLQEVAEAEGIEIDREALSFIAKRASGGLRDALTMLEQVWKFSEGKITLETVHEALGL 241
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 16128454  244 LDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEML 286
Cdd:PRK14962 242 IPIEVVRDYINAIFNGDVKRVFTVLDDVYYSGKDYEVLIQQAI 284
PRK14954 PRK14954
DNA polymerase III subunits gamma and tau; Provisional
1-465 6.33e-88

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184918 [Multi-domain]  Cd Length: 620  Bit Score: 286.45  E-value: 6.33e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGI--------TATP 72
Cdd:PRK14954   1 MSYQVIARKYRPSKFADITAQEHITHTIQNSLRMDRVGHGYIFSGLRGVGKTTAARVFAKAVNCQRMIddpvylqeVTEP 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   73 CGVCDNCREIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKF 152
Cdd:PRK14954  81 CGECESCRDFDAGTSLNISEFDAASNNSVDDIRQLRENVRYGPQKGRYRVYIIDEVHMLSTAAFNAFLKTLEEPPPHAIF 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  153 LLATTDPQKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIA-----S 227
Cdd:PRK14954 161 IFATTELHKIPATIASRCQRFNFKRIPLDEIQSQLQMICRAEGIQIDADALQLIARKAQGSMRDAQSILDQVIAfsvgsE 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  228 GDGQVSTQAVSAMLGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMV-QLSPAALGNDM 306
Cdd:PRK14954 241 AEKVIAYQGVAELLNYIDDEQFFDVTDAIAENDAVKMLEVARFVIDNGYDEQDFLEKLIEHFRNFLVLyNLRSTRLIERP 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  307 AAIELRMRELARTIPPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRALafhprmplpepEVPRQSfAPVAPTAVMTP 386
Cdd:PRK14954 321 ESVKERYQQSAGGLTPAAVMQMTDFLMKTQGELKFQFEYQFRFELALLRLI-----------ELVRND-GGVAPSPAGSP 388
                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 16128454  387 TQVPPQPQsapqqaptVPLPettsqvlaarqQLQRVQGATKAKKSEPAAATRARPVNNAALERLASVTDRVQARPVPSA 465
Cdd:PRK14954 389 DVKKKAPE--------PDLP-----------QPDRHPGPAKPEAPGARPAELPSPASAPTPEQQPPVARSAPLPPSPQA 448
PRK14956 PRK14956
DNA polymerase III subunits gamma and tau; Provisional
2-300 1.33e-84

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184920 [Multi-domain]  Cd Length: 484  Bit Score: 273.75  E-value: 1.33e-84
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    2 SYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCRE 81
Cdd:PRK14956   4 THEVLSRKYRPQFFRDVIHQDLAIGALQNALKSGKIGHAYIFFGPRGVGKTTIARILAKRLNCENPIGNEPCNECTSCLE 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   82 IEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQK 161
Cdd:PRK14956  84 ITKGISSDVLEIDAASNRGIENIRELRDNVKFAPMGGKYKVYIIDEVHMLTDQSFNALLKTLEEPPAHIVFILATTEFHK 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  162 LPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAML 241
Cdd:PRK14956 164 IPETILSRCQDFIFKKVPLSVLQDYSEKLCKIENVQYDQEGLFWIAKKGDGSVRDMLSFMEQAIVFTDSKLTGVKIRKMI 243
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  242 GTLDDDQALSLVEAMVE-ANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPA 300
Cdd:PRK14956 244 GYHGIEFLTSFIKSLIDpDNHSKSLEILESLYQEGQDIYKFLWDSIEFTHTLNLIRDSLA 303
PRK05896 PRK05896
DNA polymerase III subunits gamma and tau; Validated
1-289 1.57e-84

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235638 [Multi-domain]  Cd Length: 605  Bit Score: 277.11  E-value: 1.57e-84
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCR 80
Cdd:PRK05896   1 MSEITFYRKYRPHNFKQIIGQELIKKILVNAILNNKLTHAYIFSGPRGIGKTSIAKIFAKAINCLNPKDGDCCNSCSVCE 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   81 EIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
Cdd:PRK05896  81 SINTNQSVDIVELDAASNNGVDEIRNIIDNINYLPTTFKYKVYIIDEAHMLSTSAWNALLKTLEEPPKHVVFIFATTEFQ 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  161 KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAM 240
Cdd:PRK05896 161 KIPLTIISRCQRYNFKKLNNSELQELLKSIAKKEKIKIEDNAIDKIADLADGSLRDGLSILDQLSTFKNSEIDIEDINKT 240
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 16128454  241 LGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLL 289
Cdd:PRK05896 241 FGLVDNNKKINLIELIQKNDIEELRNLINELESKGINFEAFCRDLINLL 289
PRK06645 PRK06645
DNA polymerase III subunits gamma and tau; Validated
3-357 1.73e-82

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 180643 [Multi-domain]  Cd Length: 507  Bit Score: 269.04  E-value: 1.73e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    3 YQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITAT----PCGVCDN 78
Cdd:PRK06645   8 YIPFARKYRPSNFAELQGQEVLVKVLSYTILNDRLAGGYLLTGIRGVGKTTSARIIAKAVNCSALITENttikTCEQCTN 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   79 CREIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTD 158
Cdd:PRK06645  88 CISFNNHNHPDIIEIDAASKTSVDDIRRIIESAEYKPLQGKHKIFIIDEVHMLSKGAFNALLKTLEEPPPHIIFIFATTE 167
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  159 PQKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAI---ASGDGQVSTQ 235
Cdd:PRK06645 168 VQKIPATIISRCQRYDLRRLSFEEIFKLLEYITKQENLKTDIEALRIIAYKSEGSARDAVSILDQAAsmsAKSDNIISPQ 247
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  236 AVSAMLGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIELRMRE 315
Cdd:PRK06645 248 VINQMLGLVDSSVIIEFVEYIIHRETEKAINLINKLYGSSVNLEIFIESVSDFIAYLNKVKMLPNYSLPIYESFNDRTKS 327
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|..
gi 16128454  316 LARTIPPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRAL 357
Cdd:PRK06645 328 ILDKISLPHLSILWQIYNKGVGEIKISYNQLTETEMLVIKSI 369
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
6-471 1.63e-81

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 274.17  E-value: 1.63e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    6 LARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREIEQG 85
Cdd:PRK07764   5 LYRRYRPATFAEVIGQEHVTEPLSTALDSGRINHAYLFSGPRGCGKTSSARILARSLNCVEGPTSTPCGECDSCVALAPG 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   86 RF--VDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLP 163
Cdd:PRK07764  85 GPgsLDVTEIDAASHGGVDDARELRERAFFAPAESRYKIFIIDEAHMVTPQGFNALLKIVEEPPEHLKFIFATTEPDKVI 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  164 VTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIA-SGDGQVSTQAVSAMLG 242
Cdd:PRK07764 165 GTIRSRTHHYPFRLVPPEVMRGYLERICAQEGVPVEPGVLPLVIRAGGGSVRDSLSVLDQLLAgAGPEGVTYERAVALLG 244
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  243 TLDDdqalSLVEAMVEA----NG-------------------------ER-----VMALINEAAARGiewealLVEM--- 285
Cdd:PRK07764 245 VTDS----ALIDEAVDAlaagDGaalfgtvdrvieaghdprrfaedllERlrdliVLQAVPDAAERG------LVDApad 314
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  286 -LGLLHRIAMVqLSPAALGNdMAAI------EL------RMR-EL--ARTIPPTDiqlyYQT--LLIGRKElpyAPDRRM 347
Cdd:PRK07764 315 qLDRMRAQAQR-LGPAELTR-AADVvndgltEMrgatspRLLlELlcARMLLPSA----SDDerGLLARLE---RLERRL 385
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  348 GVEMTLLRALAFHPRMPlpePEVPRQSFAPVAPTAVMTPTQVPPQPQSAPQQAPTVPLPETTSQVLAARQQLQRVQGATK 427
Cdd:PRK07764 386 GVAGGAGAPAAAAPSAA---AAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAP 462
                        490       500       510       520
                 ....*....|....*....|....*....|....*....|....
gi 16128454  428 AKKSEPAAATRARPVNNAALERLASVTDrvQARPVPSALEKAPA 471
Cdd:PRK07764 463 SAQPAPAPAAAPEPTAAPAPAPPAAPAP--AAAPAAPAAPAAPA 504
PRK14963 PRK14963
DNA polymerase III subunits gamma and tau; Provisional
6-427 1.61e-78

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184927 [Multi-domain]  Cd Length: 504  Bit Score: 258.23  E-value: 1.61e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    6 LARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCeTGITATPCGVCDNCREIEQG 85
Cdd:PRK14963   4 LYQRARPITFDEVVGQEHVKEVLLAALRQGRLGHAYLFSGPRGVGKTTTARLIAMAVNC-SGEDPKPCGECESCLAVRRG 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   86 RFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVT 165
Cdd:PRK14963  83 AHPDVLEIDAASNNSVEDVRDLREKVLLAPLRGGRKVYILDEAHMMSKSAFNALLKTLEEPPEHVIFILATTEPEKMPPT 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  166 ILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGdGQVSTQAVSAMLGTLD 245
Cdd:PRK14963 163 ILSRTQHFRFRRLTEEEIAGKLRRLLEAEGREAEPEALQLVARLADGAMRDAESLLERLLALG-TPVTRKQVEEALGLPP 241
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  246 DDQALSLVEAMVEanGERVMALINEA-------AARGIEwEALLVEMLGLLH-RIAM-----VQLSPAALGNDMAAIELR 312
Cdd:PRK14963 242 QERLRGIAAALAQ--GDAAEALSGAAqlyrdgfAARTLV-EGLLEAFRAALYaELGLgggprLEGAEPRLLAAMTALDEQ 318
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  313 MRELARTippTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRALAFHPRMPLP-EPEVPRQSFAPVAPTAVMT------ 385
Cdd:PRK14963 319 MERFARR---SDALSLELALLHALLALGGAPSEGVAAVAPPAPAPADLTQRLNRlEKEVRSLRSAPTAAATAAGaplpdf 395
                        410       420       430       440
                 ....*....|....*....|....*....|....*....|...
gi 16128454  386 -PTQVPPQPQSAPQQAPTVPLPETTSQVLAARQQLQRVQGATK 427
Cdd:PRK14963 396 dPRPRGPPAPEPARSAEAPPLVAPAAAPAGLALRWRDVLAALK 438
PRK14952 PRK14952
DNA polymerase III subunits gamma/tau;
4-357 6.42e-76

DNA polymerase III subunits gamma/tau;


Pssm-ID: 237866 [Multi-domain]  Cd Length: 584  Bit Score: 253.65  E-value: 6.42e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    4 QVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREIE 83
Cdd:PRK14952   1 MALYRKYRPATFAEVVGQEHVTEPLSSALDAGRINHAYLFSGPRGCGKTSSARILARSLNCAQGPTATPCGVCESCVALA 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   84 QGR--FVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQK 161
Cdd:PRK14952  81 PNGpgSIDVVELDAASHGGVDDTRELRDRAFYAPAQSRYRIFIVDEAHMVTTAGFNALLKIVEEPPEHLIFIFATTEPEK 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  162 LPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIA-SGDGQVSTQAVSAM 240
Cdd:PRK14952 161 VLPTIRSRTHHYPFRLLPPRTMRALIARICEQEGVVVDDAVYPLVIRAGGGSPRDTLSVLDQLLAgAADTHVTYQRALGL 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  241 LGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSP--AALGNDMAAIEL--RMREL 316
Cdd:PRK14952 241 LGATDVALIDDAVDALAADDAAALFGAIESVIDAGHDPRRFATDLLERFRDLIVLQAVPdaAARGVVDAPEDVleRMREQ 320
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|.
gi 16128454  317 ARTIPPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRAL 357
Cdd:PRK14952 321 AARIGLATLTRYAEVVQAGLGEMRGATAPRLLLEVVCARLL 361
PRK14970 PRK14970
DNA polymerase III subunits gamma and tau; Provisional
5-302 2.05e-70

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184934 [Multi-domain]  Cd Length: 367  Bit Score: 232.46  E-value: 2.05e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    5 VLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCeTGITATpcgvcdncreiEQ 84
Cdd:PRK14970   6 VSARKYRPQTFDDVVGQSHITNTLLNAIENNHLAQALLFCGPRGVGKTTCARILARKINQ-PGYDDP-----------NE 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   85 GRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPV 164
Cdd:PRK14970  74 DFSFNIFELDAASNNSVDDIRNLIDQVRIPPQTGKYKIYIIDEVHMLSSAAFNAFLKTLEEPPAHAIFILATTEKHKIIP 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  165 TILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAMLGTL 244
Cdd:PRK14970 154 TILSRCQIFDFKRITIKDIKEHLAGIAVKEGIKFEDDALHIIAQKADGALRDALSIFDRVVTFCGKNITRQAVTENLNIL 233
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 16128454  245 DDDQALSLVEAMVEANGERVMALINEAAARGIEWEaLLVEMLGLLHRIAMVQLSPAAL 302
Cdd:PRK14970 234 DYDTYINVTDLILENKIPELLLAFNEILRKGFDGH-HFIAGLASHFRDLMVSKTPATI 290
DNA_pol3_tau_5 pfam12170
DNA polymerase III tau subunit V interacting with alpha; This domain family is found in ...
500-640 2.19e-67

DNA polymerase III tau subunit V interacting with alpha; This domain family is found in bacteria, and is approximately 140 amino acids in length. The family is found in association with pfam00004. Domains I-III are shared between the tau and the gamma subunits, while most of the DnaB-binding Domain IV and all of the alpha-interacting Domain V are unique to tau. The extreme C-terminal region of this domain 5 is the part which interacts with the alpha subunit of the DNA polymerase III holoenzyme.


Pssm-ID: 432380 [Multi-domain]  Cd Length: 142  Bit Score: 216.35  E-value: 2.19e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   500 ALEHEKTPELAAKLAAEAIERDPWAAQVSQLSLPKLVEQVALNAWKEE-SDNAVCLHLRSSQRHLNNRGAQQKLAEALSM 578
Cdd:pfam12170   1 ALEHEKTPELAAKLIEEALERDPWAALIERLGLPKLVQQLALNSVLEQqQDDQILLHLRSSQRHLNSDSAQKALAEALSE 80
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 16128454   579 LKGSTVELTIVEDDNPAVRTPLEWRQAIYEEKLAQARESIIADNNIQTLRRFFDAELDEESI 640
Cdd:pfam12170  81 LLGKPVELTITEGDDPEQKTPLEWRQAIYEEKLEQARQSLQADPNVQLLQQRFDAELDEDSI 142
DNA_pol3_delta2 pfam13177
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ...
20-179 3.66e-51

DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.


Pssm-ID: 433013 [Multi-domain]  Cd Length: 161  Bit Score: 174.32  E-value: 3.66e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    20 GQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREIEQGRFVDLIEIDAASRT 99
Cdd:pfam13177   1 GQPEAIQLLQNSLENGRLSHAYLFSGPEGVGKLELALAFAKALFCEEPGDDLPCGQCRSCRRIESGNHPDLVIIEPEGQS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   100 -KVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVTILSRCLQFHLKAL 178
Cdd:pfam13177  81 iKIDQIRELQKEFSKSPYEGKKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRCQIIRFKPL 160

                  .
gi 16128454   179 D 179
Cdd:pfam13177 161 S 161
HolB COG0470
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
21-318 5.37e-49

DNA polymerase III, delta prime subunit [Replication, recombination and repair];


Pssm-ID: 440238 [Multi-domain]  Cd Length: 289  Bit Score: 172.85  E-value: 5.37e-49
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  21 QEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDnCREIEQGRFVDLIEI--DAASR 98
Cdd:COG0470   1 QEEAWEQLLAAAESGRLPHALLLHGPPGIGKTTLALALARDLLCENPEGGKACGQCH-SRLMAAGNHPDLLELnpEEKSD 79
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  99 T-KVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVTILSRCLQFHLKA 177
Cdd:COG0470  80 QiGIDQIRELGEFLSLTPLEGGRKVVIIDEADAMNEAAANALLKTLEEPPKNTPFILIANDPSRLLPTIRSRCQVIRFRP 159
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454 178 LDVEQIRHQLEhilnEEHIAHEprALQLLARAAEGSLRDALSLTDQAiasgdgQVSTQAVSAMLGTLDDDQALSLVEamv 257
Cdd:COG0470 160 PSEEEALAWLR----EEGVDED--ALEAILRLAGGDPRAAINLLQAL------AGRKELLEDLAALLSRDRALELLD--- 224
                       250       260       270       280       290       300
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 16128454 258 eangervmALINEAAARGIEWeallveMLGLLHRIAMVQLSPAALGNDMAAIELRMRELAR 318
Cdd:COG0470 225 --------ALLKAEALELLDW------LLKWLLDNLPLEYAGEDLARAYEALSEADRRLGR 271
holB TIGR00678
DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' ...
25-217 1.03e-48

DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' subunit of DNA polymerase III. Delta' is homologous to the gamma and tau subunits, which form an outgroup for phylogenetic comparison. The gamma/tau branch of the tree is much more tighly conserved than the delta' branch, and some members of that branch score more highly against this model than some proteins classisified as delta'. The noise cutoff is set to detect weakly scoring delta' subunits rather than to exclude gamma/tau subunits. At position 126-127 of the seed alignment, this family lacks the HM motif of gamma/tau; at 132 it has a near-invariant A vs. an invariant F in gamma/tau. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273213 [Multi-domain]  Cd Length: 188  Bit Score: 168.57  E-value: 1.03e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    25 LTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREIEQGRFVDLIEIDA-ASRTKVED 103
Cdd:TIGR00678   1 YQQLKRALEKGRLAHAYLFTGPEGVGKELLALALAKALLCEQRGGGEPCGECHSCRLIEAGNHPDLHRLEPeGQSIKVDQ 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   104 TRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVTILSRCLQFHLKALDVEQI 183
Cdd:TIGR00678  81 VRELVEFLSRTPQESGRRVVIIEDAERMNEAAANALLKTLEEPPPNTLFILITPSPEKLLPTIRSRCQRLPFPPLSEEAL 160
                         170       180       190
                  ....*....|....*....|....*....|....
gi 16128454   184 RHQLEHILNEEHiaheprALQLLARAAEGSLRDA 217
Cdd:TIGR00678 161 LQWLIRQGISEE------AAELLLALAGGSPGRA 188
PRK08058 PRK08058
DNA polymerase III subunit delta'; Validated
21-220 2.43e-31

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181214 [Multi-domain]  Cd Length: 329  Bit Score: 124.65  E-value: 2.43e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   21 QEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREIEQGRFVDLIEI--DAASr 98
Cdd:PRK08058  11 QPVVVKMLQNSIAKNRLSHAYLFEGAKGTGKKATALWLAKSLFCLERNGVEPCGTCTNCKRIDSGNHPDVHLVapDGQS- 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   99 TKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVTILSRCLQFHLKAL 178
Cdd:PRK08058  90 IKKDQIRYLKEEFSKSGVESNKKVYIIEHADKMTASAANSLLKFLEEPSGGTTAILLTENKHQILPTILSRCQVVEFRPL 169
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 16128454  179 DVEQIRHQLEhilnEEHIahePRALQLLARAAEGSLRDALSL 220
Cdd:PRK08058 170 PPESLIQRLQ----EEGI---SESLATLLAGLTNSVEEALAL 204
PRK12402 PRK12402
replication factor C small subunit 2; Reviewed
9-315 5.35e-29

replication factor C small subunit 2; Reviewed


Pssm-ID: 237090 [Multi-domain]  Cd Length: 337  Bit Score: 118.17  E-value: 5.35e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    9 KWRPQTFADVVGQEHVLTALANGLSLGRIHHaYLFSGTRGVGKTSIARLLAKGL---NCETGITATPcgVCD----NCRE 81
Cdd:PRK12402   8 KYRPALLEDILGQDEVVERLSRAVDSPNLPH-LLVQGPPGSGKTAAVRALARELygdPWENNFTEFN--VADffdqGKKY 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   82 IEQG-RFVDLIEIDAASRTKVedtRDLLDNV-----QYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLA 155
Cdd:PRK12402  85 LVEDpRFAHFLGTDKRIRSSK---IDNFKHVlkeyaSYRPLSADYKTILLDNAEALREDAQQALRRIMEQYSRTCRFIIA 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  156 TTDPQKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALsLTDQAIASGDGQVSTQ 235
Cdd:PRK12402 162 TRQPSKLIPPIRSRCLPLFFRAPTDDELVDVLESIAEAEGVDYDDDGLELIAYYAGGDLRKAI-LTLQTAALAAGEITME 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  236 AVSAMLGTLD-DDQALSLVEAMVEANGERVMALIneaaargiewEALLV-------EMLGLLHRIAMVQLSP---AALGN 304
Cdd:PRK12402 241 AAYEALGDVGtDEVIESLLDAAEAGDFTDARKTL----------DDLLIdeglsggEVLEELLRVARSRYRGdnlARLHR 310
                        330
                 ....*....|.
gi 16128454  305 DMAAIELRMRE 315
Cdd:PRK12402 311 LAADADARLTD 321
DNA_pol3_tau_4 pfam12168
DNA polymerase III subunits tau domain IV DnaB-binding; This domain family is found in ...
417-498 6.00e-29

DNA polymerase III subunits tau domain IV DnaB-binding; This domain family is found in bacteria, and is approximately 80 amino acids in length. The family is found in association with pfam00004. Domains I-III are shared between the tau and the gamma subunits, while most of the DnaB-binding Domain IV and all of the alpha-interacting Domain V are unique to tau.


Pssm-ID: 432378  Cd Length: 82  Bit Score: 109.92  E-value: 6.00e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   417 QQLQRVQGATKAKKSEPAAAtRARPVNNAaLERLASVTDRVQARPVPSAL--EKAPAKKEAYRWKATTPVMQQKEVVATP 494
Cdd:pfam12168   1 SQLQRQQGGTPTKKAEPASA-KAKPVNSA-LERLASVTERSQVSPAAAAAeqENKPEKKEAYRWKATQPVEEEVKPVATP 78

                  ....
gi 16128454   495 KALK 498
Cdd:pfam12168  79 KALK 82
DNA_pol3_gamma3 pfam12169
DNA polymerase III subunits gamma and tau domain III; This domain family is found in bacteria, ...
232-367 4.43e-27

DNA polymerase III subunits gamma and tau domain III; This domain family is found in bacteria, and is approximately 110 amino acids in length. The family is found in association with pfam00004. Domains I-III are shared between the tau and the gamma subunits, while most of the DnaB-binding Domain IV and all of the alpha-interacting Domain V are unique to tau.


Pssm-ID: 432379 [Multi-domain]  Cd Length: 143  Bit Score: 106.97  E-value: 4.43e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   232 VSTQAVSAMLGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSP-AALGNDMAAIE 310
Cdd:pfam12169   1 VTAAQVRDMLGLADRGRVLDLLEALLEGDAAAALAELRDQYDAGADPVVVLRDLLELIHNLTRLKVAPdAADDLLLPEEE 80
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 16128454   311 L-RMRELARTIPPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRaLAFHPRMPLPE 367
Cdd:pfam12169  81 RaRLAELAEKLSPEVLHRLWQMLLKGIEEVPNAPDPRQAAEMVLLR-LAYAASLPPPE 137
PRK08699 PRK08699
DNA polymerase III subunit delta'; Validated
36-182 6.39e-27

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181538 [Multi-domain]  Cd Length: 325  Bit Score: 111.89  E-value: 6.39e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   36 RIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITA-TPCGVCDNCREIEQGRFVDLIEIDAASR----------TKVEDT 104
Cdd:PRK08699  19 RRPNAWLFAGKKGIGKTAFARFAAQALLCETPAPGhKPCGECMSCHLFGQGSHPDFYEITPLSDepengrkllqIKIDAV 98
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 16128454  105 RDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVTILSRCLQFHLKALDVEQ 182
Cdd:PRK08699  99 REIIDNVYLTSVRGGLRVILIHPAESMNLQAANSLLKVLEEPPPQVVFLLVSHAADKVLPTIKSRCRKMVLPAPSHEE 176
PRK13342 PRK13342
recombination factor protein RarA; Reviewed
6-228 3.83e-24

recombination factor protein RarA; Reviewed


Pssm-ID: 237355 [Multi-domain]  Cd Length: 413  Bit Score: 105.17  E-value: 3.83e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    6 LARKWRPQTFADVVGQEHVL---TALANGLSLGRIHHAyLFSGTRGVGKTSIARLLAKGLNCEtgitatpcgvcdncrei 82
Cdd:PRK13342   2 LAERMRPKTLDEVVGQEHLLgpgKPLRRMIEAGRLSSM-ILWGPPGTGKTTLARIIAGATDAP----------------- 63
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   83 eqgrfvdLIEIDAASrTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEppEHVKFLLATT-DPQ- 160
Cdd:PRK13342  64 -------FEALSAVT-SGVKDLREVIEEARQRRSAGRRTILFIDEIHRFNKAQQDALLPHVED--GTITLIGATTeNPSf 133
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 16128454  161 KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEE---HIAHEPRALQLLARAAEGSLRDALSLTDQAIASG 228
Cdd:PRK13342 134 EVNPALLSRAQVFELKPLSEEDIEQLLKRALEDKergLVELDDEALDALARLANGDARRALNLLELAALGV 204
PRK07940 PRK07940
DNA polymerase III subunit delta'; Validated
15-282 8.35e-24

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236134 [Multi-domain]  Cd Length: 394  Bit Score: 103.84  E-value: 8.35e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   15 FADVVGQEHVLTAL------ANGLSLGRIH---HAYLFSGTRGVGKTSIARLLAKGLNCeTGITATPCGVCDNCREIEQG 85
Cdd:PRK07940   4 WDDLVGQEAVVAELraaaraARADVAAAGSgmtHAWLFTGPPGSGRSVAARAFAAALQC-TDPDEPGCGECRACRTVLAG 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   86 RFVDLIEIDAASRT-KVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPV 164
Cdd:PRK07940  83 THPDVRVVAPEGLSiGVDEVRELVTIAARRPSTGRWRIVVIEDADRLTERAANALLKAVEEPPPRTVWLLCAPSPEDVLP 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  165 TILSRCLQFHLKALDVEQIRHQLehiLNEEHIAHEpRAlQLLARAAEGSLRDA--LSLTDQAIASGDgqvstQAVSAMLG 242
Cdd:PRK07940 163 TIRSRCRHVALRTPSVEAVAEVL---VRRDGVDPE-TA-RRAARASQGHIGRArrLATDEEARARRA-----EVLNLALR 232
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 16128454  243 TLDDDQALSLVEAMVEANGERVMALINEAAARgiEWEALL 282
Cdd:PRK07940 233 LARVSDAVAAAEELVKAAEAEAKALTAERDEA--ETEELR 270
HLD_clamp_pol_III_gamma_tau cd18137
helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit ...
178-242 3.54e-23

helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit gamma/tau is part of the DNA polymerase III holoenzyme. Gamma and tau subunits are isoforms, both containing the helical lid domain. Gamma interacts with the delta subunit to transfer the beta subunit on the DNA while tau serves as a scaffold to help in the dimerization of the core complex. Both are members of the clamp-loader clade of the AAA+ superfamily.


Pssm-ID: 350839 [Multi-domain]  Cd Length: 65  Bit Score: 92.95  E-value: 3.54e-23
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 16128454 178 LDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAMLG 242
Cdd:cd18137   1 ISVEDIVGRLAHILEKEGIEIEDEALELIARAAEGSMRDALSLLDQAIAFGGGRVTLDDVREMLG 65
PRK05707 PRK05707
DNA polymerase III subunit delta'; Validated
35-223 4.61e-22

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180215 [Multi-domain]  Cd Length: 328  Bit Score: 97.47  E-value: 4.61e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   35 GRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREIEQGRFVDL--IEIDAASRT-KVEDTRDLLDNV 111
Cdd:PRK05707  19 GRHPHAYLLHGPAGIGKRALAERLAAALLCEAPQGGGACGSCKGCQLLRAGSHPDNfvLEPEEADKTiKVDQVRELVSFV 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  112 QYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVTILSRCLQFHLKALDVEQIRHQLEHIL 191
Cdd:PRK05707  99 VQTAQLGGRKVVLIEPAEAMNRNAANALLKSLEEPSGDTVLLLISHQPSRLLPTIKSRCQQQACPLPSNEESLQWLQQAL 178
                        170       180       190
                 ....*....|....*....|....*....|..
gi 16128454  192 NEEhiaHEPRALQLLARAAEGSLRdALSLTDQ 223
Cdd:PRK05707 179 PES---DERERIELLTLAGGSPLR-ALQLHEQ 206
PRK09112 PRK09112
DNA polymerase III subunit delta'; Validated
12-275 3.69e-20

DNA polymerase III subunit delta'; Validated


Pssm-ID: 169667 [Multi-domain]  Cd Length: 351  Bit Score: 92.41  E-value: 3.69e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   12 PQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCD------NCREIEQG 85
Cdd:PRK09112  19 PSENTRLFGHEEAEAFLAQAYREGKLHHALLFEGPEGIGKATLAFHLANHILSHPDPAEAPETLADpdpaspVWRQIAQG 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   86 ---------RFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLAT 156
Cdd:PRK09112  99 ahpnllhitRPFDEKTGKFKTAITVDEIRRVGHFLSQTSGDGNWRIVIIDPADDMNRNAANAILKTLEEPPARALFILIS 178
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  157 TDPQKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRalQLLARAAEGSLRDALSLtdqaIASGDGQVStQA 236
Cdd:PRK09112 179 HSSGRLLPTIRSRCQPISLKPLDDDELKKALSHLGSSQGSDGEIT--EALLQRSKGSVRKALLL----LNYGGLEII-AT 251
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 16128454  237 VSAMLGTLDDD--------QALSLVEAMV------EANGERVMALINEAAARG 275
Cdd:PRK09112 252 IDQLLAGSGPDarkahklaDALSGRESEVqfdffrDHLLDRIMAEARRAAEAG 304
PRK07471 PRK07471
DNA polymerase III subunit delta'; Validated
11-267 3.23e-19

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236022 [Multi-domain]  Cd Length: 365  Bit Score: 89.70  E-value: 3.23e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   11 RPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTS----IARLLAKGLNCETGITATPCGVCD------NCR 80
Cdd:PRK07471  14 HPRETTALFGHAAAEAALLDAYRSGRLHHAWLIGGPQGIGKATlayrMARFLLATPPPGGDGAVPPPTSLAidpdhpVAR 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   81 EIEQGRFVDLIEI-----DAASRTK----VEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVK 151
Cdd:PRK07471  94 RIAAGAHGGLLTLerswnEKGKRLRtvitVDEVRELISFFGLTAAEGGWRVVIVDTADEMNANAANALLKVLEEPPARSL 173
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  152 FLLATTDPQKLPVTILSRCLQFHLKALDVEqirhQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLtdqaiASGDGQ 231
Cdd:PRK07471 174 FLLVSHAPARLLPTIRSRCRKLRLRPLAPE----DVIDALAAAGPDLPDDPRAALAALAEGSVGRALRL-----AGGDGL 244
                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 16128454  232 VSTQAVSAMLGTL---DDDQALSLVEAMVEANGERVMAL 267
Cdd:PRK07471 245 ALYRRLTALLDTLprlDRRALHALADAAAGRDRAARFAL 283
PRK07399 PRK07399
DNA polymerase III subunit delta'; Validated
15-214 2.31e-18

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236011 [Multi-domain]  Cd Length: 314  Bit Score: 86.49  E-value: 2.31e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   15 FADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLncetgITATPCGVCDNCReIEQGRFVDLIEI- 93
Cdd:PRK07399   3 FANLIGQPLAIELLTAAIKQNRIAPAYLFAGPEGVGRKLAALCFIEGL-----LSQGSPSKNIRRR-LEEGNHPDLLWVe 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   94 -------------DAASRT---------KVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEpPEHVK 151
Cdd:PRK07399  77 ptyqhqgklitasEAEEAGlkrkappqiRLEQIREIKRFLSRPPLEAPRKVVVIEDAETMNEAAANALLKTLEE-PGNGT 155
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 16128454  152 FLLATTDPQKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSL 214
Cdd:PRK07399 156 LILIAPSPESLLPTIVSRCQIIPFYRLSDEQLEQVLKRLGDEEILNINFPELLALAQGSPGAA 218
PRK07276 PRK07276
DNA polymerase III subunit delta'; Validated
32-188 2.39e-18

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180916 [Multi-domain]  Cd Length: 290  Bit Score: 85.84  E-value: 2.39e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   32 LSLGRIHHAYLFSGtrGVGKTSIARLLAKGLNCETGITATPCGVCDNCREIEQGRFVDLIEIDAASRT-KVEDTRDLLDN 110
Cdd:PRK07276  18 LEQDRLNHAYLFSG--DFASFEMALFLAQSLFCEQKEGVLPCGHCRSCRLIEQGEFSDVTVIEPQGQViKTDTIRELVKN 95
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 16128454  111 VQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVTILSRCLQFHLKAlDVEQIRHQLE 188
Cdd:PRK07276  96 FSQSGYEGKQQVFIIKDADKMHVNAANSLLKVIEEPQSEIYIFLLTNDENKVLPTIKSRTQIFHFPK-NEAYLIQLLE 172
HLD_clamp cd18133
helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit ...
178-241 3.01e-18

helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit complexes that play an important role in DNA replication. They open sliding clamps for assembly and close them around DNA, specifically targeting them to sites where DNA synthesis is initiated and orienting them correctly for replication. The subunits belong to the clamp loader clade of AAA+ superfamily.


Pssm-ID: 350838 [Multi-domain]  Cd Length: 65  Bit Score: 79.05  E-value: 3.01e-18
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 16128454 178 LDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGD-GQVSTQAVSAML 241
Cdd:cd18133   1 LDQEQLKRRLAAIAEQEKLKLDDAALQALAYISEGDLRKALNALQRAAALGDdGKISLDRVYQAV 65
PRK06964 PRK06964
DNA polymerase III subunit delta'; Validated
36-175 4.06e-18

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235898 [Multi-domain]  Cd Length: 342  Bit Score: 85.97  E-value: 4.06e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   36 RIHHAYLFSGTRGVGKTSIARLLAKGLNCETGIT-ATPCGVCDNCREIEQGRFVD--------------LIEIDAA---- 96
Cdd:PRK06964  19 RLPHALLLHGQAGIGKLDFAQHLAQGLLCETPQPdGEPCGTCAACNWFAQGNHPDyrivrpealaaeapGAADEAKeada 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   97 ------SRT-----KVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVT 165
Cdd:PRK06964  99 deggkkTKApskeiKIEQVRALLDFCGVGTHRGGARVVVLYPAEALNVAAANALLKTLEEPPPGTVFLLVSARIDRLLPT 178
                        170
                 ....*....|
gi 16128454  166 ILSRCLQFHL 175
Cdd:PRK06964 179 ILSRCRQFPM 188
PRK05564 PRK05564
DNA polymerase III subunit delta'; Validated
15-194 2.67e-17

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180132 [Multi-domain]  Cd Length: 313  Bit Score: 83.16  E-value: 2.67e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   15 FADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLA-KGLNcetgitatpcgvcdncrEIEQGRFVDLIE- 92
Cdd:PRK05564   3 FHTIIGHENIKNRIKNSIIKNRFSHAHIIVGEDGIGKSLLAKEIAlKILG-----------------KSQQREYVDIIEf 65
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   93 -IDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVTILSRCL 171
Cdd:PRK05564  66 kPINKKSIGVDDIRNIIEEVNKKPYEGDKKVIIIYNSEKMTEQAQNAFLKTIEEPPKGVFIILLCENLEQILDTIKSRCQ 145
                        170       180
                 ....*....|....*....|....*.
gi 16128454  172 QFHLKALDVEQIRHQLE---HILNEE 194
Cdd:PRK05564 146 IYKLNRLSKEEIEKFISykyNDIKEE 171
RarA COG2256
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, ...
6-242 4.22e-17

Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, recombination and repair];


Pssm-ID: 441857 [Multi-domain]  Cd Length: 439  Bit Score: 83.95  E-value: 4.22e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   6 LARKWRPQTFADVVGQEHVL---TALANGLSLGRIHHAYLFsGTRGVGKTSIARLLAKGLNCEtgitatpcgvcdncrei 82
Cdd:COG2256  15 LAERMRPRTLDEVVGQEHLLgpgKPLRRAIEAGRLSSMILW-GPPGTGKTTLARLIANATDAE----------------- 76
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  83 eqgrFVDLieidAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHmlsRhsFN-----ALLKTLEEppEHVKFLLATT 157
Cdd:COG2256  77 ----FVAL----SAVTSGVKDIREVIEEARERRAYGRRTILFVDEIH---R--FNkaqqdALLPHVED--GTITLIGATT 141
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454 158 D--------PqklpvtILSRCLQFHLKALDVEQIR-------HQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTD 222
Cdd:COG2256 142 EnpsfevnsA------LLSRCRVFVLKPLSEEDLEqlleralADDERGLGGYKLELDDEALEALARLADGDARRALNALE 215
                       250       260
                ....*....|....*....|....
gi 16128454 223 QAIAS----GDGQVSTQAVSAMLG 242
Cdd:COG2256 216 LAVLSappdGVIEITLELVEEALQ 239
PRK06871 PRK06871
DNA polymerase III subunit delta'; Validated
35-170 1.10e-16

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180738 [Multi-domain]  Cd Length: 325  Bit Score: 81.70  E-value: 1.10e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   35 GRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREIEQGRFVDLIEIdAASRTK---VEDTRDLLDNV 111
Cdd:PRK06871  21 GLGHHALLFKADSGLGTEQLIRALAQWLMCQTPQGDQPCGQCHSCHLFQAGNHPDFHIL-EPIDNKdigVDQVREINEKV 99
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 16128454  112 QYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVTILSRC 170
Cdd:PRK06871 100 SQHAQQGGNKVVYIQGAERLTEAAANALLKTLEEPRPNTYFLLQADLSAALLPTIYSRC 158
PRK07993 PRK07993
DNA polymerase III subunit delta'; Validated
35-249 1.38e-16

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181190 [Multi-domain]  Cd Length: 334  Bit Score: 81.27  E-value: 1.38e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   35 GRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREIEQGRFVD---LIEIDAASRTKVEDTRDLLDNV 111
Cdd:PRK07993  21 GRGHHALLIQALPGMGDDALIYALSRWLMCQQPQGHKSCGHCRGCQLMQAGTHPDyytLTPEKGKSSLGVDAVREVTEKL 100
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  112 qYAPAR-GRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVTILSRCLQFHLKALDVEQIRHQLEHi 190
Cdd:PRK07993 101 -YEHARlGGAKVVWLPDAALLTDAAANALLKTLEEPPENTWFFLACREPARLLATLRSRCRLHYLAPPPEQYALTWLSR- 178
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 16128454  191 lneeHIAHEPRALQLLARAAEGSLRDALSL--TDQ-AIASGDGQVSTQAVS-----AMLGTLDDDQA 249
Cdd:PRK07993 179 ----EVTMSQDALLAALRLSAGAPGAALALlqPERwQQREALCQALAYALPsgdwlSLLPALNHEQA 241
rfc PRK00440
replication factor C small subunit; Reviewed
9-243 1.78e-16

replication factor C small subunit; Reviewed


Pssm-ID: 234763 [Multi-domain]  Cd Length: 319  Bit Score: 80.69  E-value: 1.78e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    9 KWRPQTFADVVGQEHVLTALANGLSLGRIHHaYLFSGTRGVGKTSIARLLAKGLNCETGItatpcgvcDNCREI----EQ 84
Cdd:PRK00440  10 KYRPRTLDEIVGQEEIVERLKSYVKEKNMPH-LLFAGPPGTGKTTAALALARELYGEDWR--------ENFLELnasdER 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   85 GrfVDLIeidaasRTKVED---TRDLLDnvqyAPargrFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQK 161
Cdd:PRK00440  81 G--IDVI------RNKIKEfarTAPVGG----AP----FKIIFLDEADNLTSDAQQALRRTMEMYSQNTRFILSCNYSSK 144
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  162 LPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTdQAIASGDGQVSTQAVSAML 241
Cdd:PRK00440 145 IIDPIQSRCAVFRFSPLKKEAVAERLRYIAENEGIEITDDALEAIYYVSEGDMRKAINAL-QAAAATGKEVTEEAVYKIT 223

                 ..
gi 16128454  242 GT 243
Cdd:PRK00440 224 GT 225
PRK06090 PRK06090
DNA polymerase III subunit delta'; Validated
28-251 9.56e-15

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180394 [Multi-domain]  Cd Length: 319  Bit Score: 75.61  E-value: 9.56e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   28 LANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETgITATPCGVCDNCREIEQGRFVDLIEIDAASRTK---VEDT 104
Cdd:PRK06090  15 WKAGLDAGRIPGALLLQSDEGLGVESLVELFSRALLCQN-YQSEACGFCHSCELMQSGNHPDLHVIKPEKEGKsitVEQI 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  105 RDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVTILSRCLQFHLKALDVEQIR 184
Cdd:PRK06090  94 RQCNRLAQESSQLNGYRLFVIEPADAMNESASNALLKTLEEPAPNCLFLLVTHNQKRLLPTIVSRCQQWVVTPPSTAQAM 173
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 16128454  185 HQlehiLNEEHIAHEPRALQL--------LARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAMLGTLDDDQALS 251
Cdd:PRK06090 174 QW----LKGQGITVPAYALKLnmgsplktLAMMKEGGLEKYHKLERQLVDALSGPVSDQLKCASLIAADPLTHLS 244
PRK04195 PRK04195
replication factor C large subunit; Provisional
9-256 3.25e-13

replication factor C large subunit; Provisional


Pssm-ID: 235250 [Multi-domain]  Cd Length: 482  Bit Score: 72.26  E-value: 3.25e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    9 KWRPQTFADVVGQEHVLTAL---ANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNcetgitatpcgvcdncreieqg 85
Cdd:PRK04195   7 KYRPKTLSDVVGNEKAKEQLrewIESWLKGKPKKALLLYGPPGVGKTSLAHALANDYG---------------------- 64
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   86 rfVDLIEIDAA-SRTKvED----------TRDLLdnvqyapARGRfKVYLIDEVHMLS----RHSFNALLKTLEEPPEHV 150
Cdd:PRK04195  65 --WEVIELNASdQRTA-DViervageaatSGSLF-------GARR-KLILLDEVDGIHgnedRGGARAILELIKKAKQPI 133
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  151 kfLLATTDPQKLP-VTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDAlsLTD-QAIASG 228
Cdd:PRK04195 134 --ILTANDPYDPSlRELRNACLMIEFKRLSTRSIVPVLKRICRKEGIECDDEALKEIAERSGGDLRSA--INDlQAIAEG 209
                        250       260
                 ....*....|....*....|....*...
gi 16128454  229 DGQVSTQAVSAMlgtLDDDQALSLVEAM 256
Cdd:PRK04195 210 YGKLTLEDVKTL---GRRDREESIFDAL 234
44 PHA02544
clamp loader, small subunit; Provisional
9-203 3.54e-13

clamp loader, small subunit; Provisional


Pssm-ID: 222866 [Multi-domain]  Cd Length: 316  Bit Score: 70.79  E-value: 3.54e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    9 KWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLakglncetgitatpcgvcdnCREIEqgrfV 88
Cdd:PHA02544  14 KYRPSTIDECILPAADKETFKSIVKKGRIPNMLLHSPSPGTGKTTVAKAL--------------------CNEVG----A 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   89 DLIEIDAASrTKVEDTRDLLDNvqYAPA---RGRFKVYLIDEVHMLSRHSFNALLKTL-EEPPEHVKFLLATTDPQKLPV 164
Cdd:PHA02544  70 EVLFVNGSD-CRIDFVRNRLTR--FASTvslTGGGKVIIIDEFDRLGLADAQRHLRSFmEAYSKNCSFIITANNKNGIIE 146
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 16128454  165 TILSRCLQFHL-KALDVEQIR------HQLEHILNEEHIAHEPRAL 203
Cdd:PHA02544 147 PLRSRCRVIDFgVPTKEEQIEmmkqmiVRCKGILEAEGVEVDMKVL 192
PRK05917 PRK05917
DNA polymerase III subunit delta'; Validated
101-175 1.22e-12

DNA polymerase III subunit delta'; Validated


Pssm-ID: 102059 [Multi-domain]  Cd Length: 290  Bit Score: 69.05  E-value: 1.22e-12
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 16128454  101 VEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVTILSRCLQFHL 175
Cdd:PRK05917  77 IETPRAIKKQIWIHPYESPYKIYIIHEADRMTLDAISAFLKVLEDPPQHGVIILTSAKPQRLPPTIRSRSLSIHI 151
PRK14949 PRK14949
DNA polymerase III subunits gamma and tau; Provisional
366-640 1.68e-12

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237863 [Multi-domain]  Cd Length: 944  Bit Score: 70.91  E-value: 1.68e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  366 PEPEVPRQSFAPV--APTAVMTPTQVPPQPQSAPQQAPTVPLPETTSQVLAARQQLQRVQGATKAKKSEP---------- 433
Cdd:PRK14949 637 KKSSADRKPKTPPsrAPPASLSKPASSPDASQTSASFDLDPDFELATHQSVPEAALASGSAPAPPPVPDPydrppweeap 716
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  434 -AAATRARPVNNAALERLASVTDRV--QARPVPSALEKAPAKKEAYRWKATTPVMQQ--KEVVATPKALKKALEHEktpe 508
Cdd:PRK14949 717 eVASANDGPNNAAEGNLSESVEDASnsELQAVEQQATHQPQVQAEAQSPASTTALTQtsSEVQDTELNLVLLSSGS---- 792
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  509 laaklaaeaIERDP----WAAQVSQLSLPKLVEQVALNAWKEESDNAVCLHLRSSQRHLNNRGAQQKLAEALSMLKGSTV 584
Cdd:PRK14949 793 ---------ITGHPldlhWYKLMASLEVGGRVRQLAVNSVCQTQSNPLPLLLKPDQKHLAADVAIVQLEQALSAALGNPR 863
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 16128454  585 ELTIVEDDNPAVRTPLEWRQAIYEEKLAQARESIIADNNIQTLRRFFDAELDEESI 640
Cdd:PRK14949 864 RVEVVIGVDPKRETPLELRKRFHQELLQQAHQSLITDDNVQWLIQRMGAELDADSL 919
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
19-170 1.28e-11

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 62.93  E-value: 1.28e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  19 VGQEHVLTALANGLSLGRIHHaYLFSGTRGVGKTSIARLLAKGLNcetgitatpcgvcdncreieqGRFVDLIEIDAASR 98
Cdd:cd00009   1 VGQEEAIEALREALELPPPKN-LLLYGPPGTGKTTLARAIANELF---------------------RPGAPFLYLNASDL 58
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  99 TKVEDTRDLLDNVQYAPARGRFK-----VYLIDEVHMLSRHSFNALLKTLEE------PPEHVKFLLATTDP--QKLPVT 165
Cdd:cd00009  59 LEGLVVAELFGHFLVRLLFELAEkakpgVLFIDEIDSLSRGAQNALLRVLETlndlriDRENVRVIGATNRPllGDLDRA 138

                ....*
gi 16128454 166 ILSRC 170
Cdd:cd00009 139 LYDRL 143
PRK05818 PRK05818
DNA polymerase III subunit delta'; Validated
72-173 3.12e-11

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235618 [Multi-domain]  Cd Length: 261  Bit Score: 64.08  E-value: 3.12e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   72 PCGVCDNCREIEQGRFVDLIEI-DAASRTKVEDTRDLLD--NVQYAPARGRfKVYLIDEVHMLSRHSFNALLKTLEEPPE 148
Cdd:PRK05818  39 FCKTCESCLKILNGKYNDFYLIfDQKNPIKKEDALSIINklNRPSVESNGK-KIYIIYGIEKLNKQSANSLLKLIEEPPK 117
                         90       100
                 ....*....|....*....|....*
gi 16128454  149 HVKFLLATTDPQKLPVTILSRCLQF 173
Cdd:PRK05818 118 NTYGIFTTRNENNILNTILSRCVQY 142
PRK07132 PRK07132
DNA polymerase III subunit delta'; Validated
28-193 7.21e-10

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180855 [Multi-domain]  Cd Length: 299  Bit Score: 60.51  E-value: 7.21e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   28 LANGLSLGRIHHAYLFSGT-RGVGKTSIARLLAKGLNCETGitatpcGVCDNCREIEqGRFVDLIEIDaasrTKVEDTRD 106
Cdd:PRK07132   8 LDNSATQNKISHSFLLKSNyNEDIDEKILYFLNKFNNLQIT------NLNEQELPAN-IILFDIFDKD----LSKSEFLS 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  107 LLDNVQYAP-ARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVTILSRCLQFHLKALDVEQIrh 185
Cdd:PRK07132  77 AINKLYFSSfVQSQKKILIIKNIEKTSNSLLNALLKTIEEPPKDTYFLLTTKNINKVLPTIVSRCQVFNVKEPDQQKI-- 154

                 ....*...
gi 16128454  186 qLEHILNE 193
Cdd:PRK07132 155 -LAKLLSK 161
PRK08769 PRK08769
DNA polymerase III subunit delta'; Validated
32-175 9.71e-10

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181551 [Multi-domain]  Cd Length: 319  Bit Score: 60.36  E-value: 9.71e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   32 LSLGRIHHAYLFSGTRGVGKTSIARLLAKGLnceTGITATPCGVCDNCREIEQGRFVDLIEID-AASRTK--------VE 102
Cdd:PRK08769  20 LDAGRLGHGLLICGPEGLGKRAVALALAEHV---LASGPDPAAAQRTRQLIAAGTHPDLQLVSfIPNRTGdklrteivIE 96
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 16128454  103 DTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVTILSRC--LQFHL 175
Cdd:PRK08769  97 QVREISQKLALTPQYGIAQVVIVDPADAINRAACNALLKTLEEPSPGRYLWLISAQPARLPATIRSRCqrLEFKL 171
AAA pfam00004
ATPase family associated with various cellular activities (AAA); AAA family proteins often ...
41-170 2.06e-09

ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.


Pssm-ID: 459627 [Multi-domain]  Cd Length: 130  Bit Score: 56.06  E-value: 2.06e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    41 YLFSGTRGVGKTSIARLLAKglncETGItatpcgvcdNCREIEQGRFVDLIEIDAASRtkvedTRDLLDNVQyapaRGRF 120
Cdd:pfam00004   1 LLLYGPPGTGKTTLAKAVAK----ELGA---------PFIEISGSELVSKYVGESEKR-----LRELFEAAK----KLAP 58
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 16128454   121 KVYLIDEVHMLSRHSF-----------NALLKTLEEP---PEHVKFLLATTDPQKLPVTILSRC 170
Cdd:pfam00004  59 CVIFIDEIDALAGSRGsggdsesrrvvNQLLTELDGFtssNSKVIVIAATNRPDKLDPALLGRF 122
PRK13341 PRK13341
AAA family ATPase;
6-232 2.95e-09

AAA family ATPase;


Pssm-ID: 237354 [Multi-domain]  Cd Length: 725  Bit Score: 60.07  E-value: 2.95e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    6 LARKWRPQTFADVVGQEHVLTA---LANGLSLGRIHHAyLFSGTRGVGKTSIARLLAKGLNCE-TGITATPCGVCDNCRE 81
Cdd:PRK13341  18 LADRLRPRTLEEFVGQDHILGEgrlLRRAIKADRVGSL-ILYGPPGVGKTTLARIIANHTRAHfSSLNAVLAGVKDLRAE 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   82 IEQGRfvdlieidaaSRTKVEDTRDLLdnvqyapargrfkvyLIDEVHMLSRHSFNALLKTLEEPPehVKFLLATTDPQK 161
Cdd:PRK13341  97 VDRAK----------ERLERHGKRTIL---------------FIDEVHRFNKAQQDALLPWVENGT--ITLIGATTENPY 149
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  162 LPV--TILSRCLQFHLKALDVEQIRHQLEHILNEEH-------IAHEPRALQLLARAAEG---SLRDALSLTDQA-IASG 228
Cdd:PRK13341 150 FEVnkALVSRSRLFRLKSLSDEDLHQLLKRALQDKErgygdrkVDLEPEAEKHLVDVANGdarSLLNALELAVEStPPDE 229

                 ....
gi 16128454  229 DGQV 232
Cdd:PRK13341 230 DGLI 233
PLN03025 PLN03025
replication factor C subunit; Provisional
9-237 9.87e-09

replication factor C subunit; Provisional


Pssm-ID: 178596 [Multi-domain]  Cd Length: 319  Bit Score: 57.43  E-value: 9.87e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    9 KWRPQTFADVVGQEHVLTALANGLSLGRIHHaYLFSGTRGVGKTSIARLLAKGLncetgitatpcgVCDNCREIeqgrfv 88
Cdd:PLN03025   6 KYRPTKLDDIVGNEDAVSRLQVIARDGNMPN-LILSGPPGTGKTTSILALAHEL------------LGPNYKEA------ 66
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   89 dLIEIDAASRTKVEDTRDLL-----DNVQYAParGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLP 163
Cdd:PLN03025  67 -VLELNASDDRGIDVVRNKIkmfaqKKVTLPP--GRHKIVILDEADSMTSGAQQALRRTMEIYSNTTRFALACNTSSKII 143
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 16128454  164 VTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSlTDQAIASGDGQVSTQAV 237
Cdd:PLN03025 144 EPIQSRCAIVRFSRLSDQEILGRLMKVVEAEKVPYVPEGLEAIIFTADGDMRQALN-NLQATHSGFGFVNQENV 216
PRK04132 PRK04132
replication factor C small subunit; Provisional
120-237 4.80e-08

replication factor C small subunit; Provisional


Pssm-ID: 235223 [Multi-domain]  Cd Length: 846  Bit Score: 56.39  E-value: 4.80e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  120 FKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHE 199
Cdd:PRK04132 631 FKIIFLDEADALTQDAQQALRRTMEMFSSNVRFILSCNYSSKIIEPIQSRCAIFRFRPLRDEDIAKRLRYIAENEGLELT 710
                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 16128454  200 PRALQLLARAAEGSLRDALSLTdQAIASGDGQVSTQAV 237
Cdd:PRK04132 711 EEGLQAILYIAEGDMRRAINIL-QAAAALDDKITDENV 747
PRK08485 PRK08485
DNA polymerase III subunit delta'; Validated
137-223 2.34e-06

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236274 [Multi-domain]  Cd Length: 206  Bit Score: 48.88  E-value: 2.34e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  137 NALLKTLEEPPEHVKFLLATTDPQKLPVTILSRC-------------LQFHLKALDVEQIRHQLEHILNEEHIAHEpRAL 203
Cdd:PRK08485  72 NALLKILEEPPKNICFIIVAKSKNLLLPTIRSRLiiekrkqkkpvkpLDLDLKKLDLKDIYEFLKELEKENKLSKE-ELK 150
                         90       100
                 ....*....|....*....|
gi 16128454  204 QLLARAAEGSLRDALSLTDQ 223
Cdd:PRK08485 151 ELIESLLKECVKYKIPLNEE 170
HolA COG1466
DNA polymerase III, delta subunit [Replication, recombination and repair];
121-313 3.25e-06

DNA polymerase III, delta subunit [Replication, recombination and repair];


Pssm-ID: 441075 [Multi-domain]  Cd Length: 305  Bit Score: 49.48  E-value: 3.25e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454 121 KVYLIDEVHMLSR--HSFNALLKTLEEPPEHVKFLLATTDP---QKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEH 195
Cdd:COG1466  64 RLVIVRNAEFLKKpgEGLEALEAYLANPPPDTVLVLTAGKLdkrKKLFKALEKAGVVVECYPLKERELPAWIRQRLKAAG 143
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454 196 IAHEPRALQLLARAAEGSLRDALSLTDQ--AIASGDGQVSTQAVSAMLGTLDDDQALSLVEAMVEANGERVMALINEAAA 273
Cdd:COG1466 144 LRIDPDAAQLLAERVGGDLLALAQELEKlaLYAGDGGTITLEDVEALVGDSAEFNVFDLADALLAGDAARALRILRRLLA 223
                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*
gi 16128454 274 RGIEwealLVEMLGLLHR----IAMVQLSPAALGNDMAAI-ELRM 313
Cdd:COG1466 224 EGEE----PVLILAALARqfrlLLQVKALLAQGKSLAEIAkELGV 264
HLD_clamp_RFC cd18140
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein ...
178-239 1.33e-05

helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein clamp loader complex that forms a stable ATP-dependent complex with the sliding clamp, PCNA, which binds specifically to primed DNA. RFC subunits belong to the clamp loader clade of the AAA+ superfamily.


Pssm-ID: 350842 [Multi-domain]  Cd Length: 63  Bit Score: 42.90  E-value: 1.33e-05
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 16128454 178 LDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTdQAIASGDGQVSTQAVSA 239
Cdd:cd18140   1 LSKEQIVKRLREICKKEGVKIDEEALEAIAEKSEGDMRKAINDL-QAAAAGGGVITEEDVYE 61
PRK06581 PRK06581
DNA polymerase III subunit delta'; Validated
92-177 1.96e-05

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235833 [Multi-domain]  Cd Length: 263  Bit Score: 46.76  E-value: 1.96e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   92 EIDAASRTK---VEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVTILS 168
Cdd:PRK06581  59 ETSATSNAKnisIEQIRKLQDFLSKTSAISGYKVAIIYSAELMNLNAANSCLKILEDAPKNSYIFLITSRAASIISTIRS 138

                 ....*....
gi 16128454  169 RCLQFHLKA 177
Cdd:PRK06581 139 RCFKINVRS 147
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
38-175 2.31e-05

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 44.67  E-value: 2.31e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454     38 HHAYLFSGTRGVGKTSIARLLAKGLNCETGITATpcgvcDNCREIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPAR 117
Cdd:smart00382   2 GEVILIVGPPGSGKTTLARALARELGPPGGGVIY-----IDGEDILEEVLDQLLLIIVGGKKASGSGELRLRLALALARK 76
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 16128454    118 GRFKVYLIDEVHMLSRHSFNALL--------KTLEEPPEHVKFLLATTDPQKLPVTILSRCLQFHL 175
Cdd:smart00382  77 LKPDVLILDEITSLLDAEQEALLllleelrlLLLLKSEKNLTVILTTNDEKDLGPALLRRRFDRRI 142
SpoVK COG0464
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ...
6-241 4.54e-05

AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];


Pssm-ID: 440232 [Multi-domain]  Cd Length: 397  Bit Score: 46.06  E-value: 4.54e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   6 LARKWRPQTFADVVGQEHVLTAL---------------ANGLSLGRihhAYLFSGTRGVGKTSIARLLAKGLNcetgita 70
Cdd:COG0464 147 ELLELREAILDDLGGLEEVKEELrelvalplkrpelreEYGLPPPR---GLLLYGPPGTGKTLLARALAGELG------- 216
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  71 tpcgvcdncreieqgrfVDLIEIDAAS-RTK-VEDT----RDLLDNV-QYAPArgrfkVYLIDEVHML--------SRHS 135
Cdd:COG0464 217 -----------------LPLIEVDLSDlVSKyVGETeknlREVFDKArGLAPC-----VLFIDEADALagkrgevgDGVG 274
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454 136 ---FNALLKTLEEPPEHVKFLLATTDPQKLPVTILSRC-LQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAE 211
Cdd:COG0464 275 rrvVNTLLTEMEELRSDVVVIAATNRPDLLDPALLRRFdEIIFFPLPDAEERLEIFRIHLRKRPLDEDVDLEELAEATEG 354
                       250       260       270
                ....*....|....*....|....*....|....
gi 16128454 212 GSLRD----ALSLTDQAIASGDGQVSTQAVSAML 241
Cdd:COG0464 355 LSGADirnvVRRAALQALRLGREPVTTEDLLEAL 388
RuvB_N pfam05496
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the ...
11-134 1.27e-04

Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the RuvABC revolvasome which catalyzes the resolution of Holliday junctions that arise during genetic recombination and DNA repair. Branch migration is catalyzed by the RuvB protein that is targeted to the Holliday junction by the structure specific RuvA protein. This family contains the N-terminal region of the protein.


Pssm-ID: 398900 [Multi-domain]  Cd Length: 159  Bit Score: 42.87  E-value: 1.27e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    11 RPQTFADVVGQEHVLT--------ALANGLSLGRIhhayLFSGTRGVGKTSIARLLAKGLNCETGITATPCgvcdncreI 82
Cdd:pfam05496   2 RPRTLDEYIGQEKVKEnlkifieaAKQRGEALDHV----LLYGPPGLGKTTLANIIANEMGVNIRITSGPA--------I 69
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 16128454    83 EQGRfvDLieidAASRTKVEDtRDLLdnvqyapargrfkvyLIDEVHMLSRH 134
Cdd:pfam05496  70 ERPG--DL----AAILTNLEP-GDVL---------------FIDEIHRLNRA 99
PRK04132 PRK04132
replication factor C small subunit; Provisional
9-61 2.67e-04

replication factor C small subunit; Provisional


Pssm-ID: 235223 [Multi-domain]  Cd Length: 846  Bit Score: 44.06  E-value: 2.67e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 16128454    9 KWRPQTFADVVGQEHVLTALANGLSLGRIHHaYLFSGTRGVGK--TSIARLLAKG 61
Cdd:PRK04132  12 KYRPQRLDDIVGQEHIVKRLKHYVKTGSMPH-LLFAGPPGVGKclTGDTKVIANG 65
ExeA COG3267
Type II secretory pathway ATPase component GspA/ExeA/MshM [Intracellular trafficking, ...
48-215 4.87e-04

Type II secretory pathway ATPase component GspA/ExeA/MshM [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 442498 [Multi-domain]  Cd Length: 261  Bit Score: 42.47  E-value: 4.87e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  48 GVGKTSIARLLAKGL--NCETGITATPCGvcdNCREIEQGRFVDLiEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLI 125
Cdd:COG3267  53 GTGKTTLLRRLLERLpdDVKVAYIPNPQL---SPAELLRAIADEL-GLEPKGASKADLLRQLQEFLLELAAAGRRVVLII 128
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454 126 DEVHMLSRHSFnallktleeppEHVKFLLA-TTDPQKLPVTIL-------------------SRC-LQFHLKALDVEQ-- 182
Cdd:COG3267 129 DEAQNLPPETL-----------EELRLLSNlETDSRKLLQIVLvgqpelrerlarpelrqlrQRItARYHLRPLDREEta 197
                       170       180       190
                ....*....|....*....|....*....|....*
gi 16128454 183 --IRHQLEHILNEEHIAHEPRALQLLARAAEGSLR 215
Cdd:COG3267 198 ayIEHRLKVAGGEGDPLFTPEAIEAIYRASGGIPR 232
ruvB PRK00080
Holliday junction branch migration DNA helicase RuvB;
11-133 7.50e-04

Holliday junction branch migration DNA helicase RuvB;


Pssm-ID: 234619 [Multi-domain]  Cd Length: 328  Bit Score: 42.04  E-value: 7.50e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454   11 RPQTFADVVGQEHVL--------TALANGLSLGRIhhayLFSGTRGVGKTSIARLLAKGLNCETGITATPcgvcdncrEI 82
Cdd:PRK00080  20 RPKSLDEFIGQEKVKenlkifieAAKKRGEALDHV----LLYGPPGLGKTTLANIIANEMGVNIRITSGP--------AL 87
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 16128454   83 EQGRfvDLieidAASRTKVEDtRDLLdnvqyapargrFkvylIDEVHMLSR 133
Cdd:PRK00080  88 EKPG--DL----AAILTNLEE-GDVL-----------F----IDEIHRLSP 116
RuvB COG2255
Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, ...
11-133 2.86e-03

Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, recombination and repair];


Pssm-ID: 441856 [Multi-domain]  Cd Length: 337  Bit Score: 40.45  E-value: 2.86e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454  11 RPQTFADVVGQEHVL--------TALANGLSLGRIhhayLFSGTRGVGKTSIARLLAKGLNCETGITATPCgvcdncreI 82
Cdd:COG2255  23 RPKRLDEYIGQEKVKenlkifieAAKKRGEALDHV----LLYGPPGLGKTTLAHIIANEMGVNIRITSGPA--------I 90
                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|.
gi 16128454  83 EQGRfvDLieidAASRTKVEDtRDLLdnvqyapargrFkvylIDEVHMLSR 133
Cdd:COG2255  91 EKPG--DL----AAILTNLEE-GDVL-----------F----IDEIHRLSR 119
AAA_18 pfam13238
AAA domain;
42-129 5.14e-03

AAA domain;


Pssm-ID: 433052 [Multi-domain]  Cd Length: 128  Bit Score: 37.41  E-value: 5.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    42 LFSGTRGVGKTSIARLLAKGLNCEtgitatpcgvcDNCREIEQGRFVDLIEIDAASRTKVEDTRD---LLDNVQYAPARG 118
Cdd:pfam13238   2 LITGTPGVGKTTLAKELSKRLGFG-----------DNVRDLALENGLVLGDDPETRESKRLDEDKldrLLDLLEENAALE 70
                          90
                  ....*....|.
gi 16128454   119 RFKVYLIDEVH 129
Cdd:pfam13238  71 EGGNLIIDGHL 81
Fap7 COG1936
Broad-specificity NMP kinase [Nucleotide transport and metabolism];
44-65 7.45e-03

Broad-specificity NMP kinase [Nucleotide transport and metabolism];


Pssm-ID: 441539 [Multi-domain]  Cd Length: 173  Bit Score: 37.87  E-value: 7.45e-03
                        10        20
                ....*....|....*....|..
gi 16128454  44 SGTRGVGKTSIARLLAKGLNCE 65
Cdd:COG1936   6 TGTPGTGKTTVAKLLAERLGLE 27
AAA_22 pfam13401
AAA domain;
42-155 7.55e-03

AAA domain;


Pssm-ID: 379165 [Multi-domain]  Cd Length: 129  Bit Score: 36.94  E-value: 7.55e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128454    42 LFSGTRGVGKTSIARLLAKGLNCETGITAT-----PCGVCDNCREIEQgrfvdLIEIDAASRTKVEDTRDLLdnVQYAPA 116
Cdd:pfam13401   9 VLTGESGTGKTTLLRRLLEQLPEVRDSVVFvdlpsGTSPKDLLRALLR-----ALGLPLSGRLSKEELLAAL--QQLLLA 81
                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 16128454   117 RGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLA 155
Cdd:pfam13401  82 LAVAVVLIIDEAQHLSLEALEELRDLLNLSSKLLQLILV 120
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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