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Conserved domains on  [gi|16128539|ref|NP_415088|]
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putative prophage endopeptidase RzpD [Escherichia coli str. K-12 substr. MG1655]

Protein Classification

lysis protein( domain architecture ID 10505375)

lysis protein similar to bacteriophage inner membrane subunit (lysis protein Rz) of the spanin complex, which is involved in the final step in host lysis by disrupting the outer membrane

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Phage_lysis pfam03245
Bacteriophage Rz lysis protein; This protein is involved in host lysis. This family is not ...
 29-153 1.54e-46

Bacteriophage Rz lysis protein; This protein is involved in host lysis. This family is not considered to be a peptidase according to the MEROPs database. This family Rz and the Rz1 protein (pfam06085) represent a unique example of two genes located in different reading frames in the same nucleotide sequence, which encode different proteins that are both required in the same physiological pathway.


:

Pssm-ID: 427215  Cd Length: 126  Bit Score: 147.64  E-value: 1.54e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128539    29 NAIAYKVQRDKNARELKLANAAITDMQMRQRDVAALDAKYTKELADAKAENDALRDDVAAGRRRLHIKAVCQS-VREATT 107
Cdd:pfam03245   1 EAAKQQRQVVKDASELRAANAEITDQNARIRAVAALDAKHTKELANAKSENDRLRADVAAGTRRLRINATCPAgVPKATS 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 16128539   108 ASGVDNAASPRLADTAERDYFTLRERLITMQKQLEGTQKYINEQCR 153
Cdd:pfam03245  81 AAGVGDAASARLNPAAERDYFDLRERIDENEQQLKGLQDYIRAQCQ 126
 
Name Accession Description Interval E-value
Phage_lysis pfam03245
Bacteriophage Rz lysis protein; This protein is involved in host lysis. This family is not ...
 29-153 1.54e-46

Bacteriophage Rz lysis protein; This protein is involved in host lysis. This family is not considered to be a peptidase according to the MEROPs database. This family Rz and the Rz1 protein (pfam06085) represent a unique example of two genes located in different reading frames in the same nucleotide sequence, which encode different proteins that are both required in the same physiological pathway.


Pssm-ID: 427215  Cd Length: 126  Bit Score: 147.64  E-value: 1.54e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128539    29 NAIAYKVQRDKNARELKLANAAITDMQMRQRDVAALDAKYTKELADAKAENDALRDDVAAGRRRLHIKAVCQS-VREATT 107
Cdd:pfam03245   1 EAAKQQRQVVKDASELRAANAEITDQNARIRAVAALDAKHTKELANAKSENDRLRADVAAGTRRLRINATCPAgVPKATS 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 16128539   108 ASGVDNAASPRLADTAERDYFTLRERLITMQKQLEGTQKYINEQCR 153
Cdd:pfam03245  81 AAGVGDAASARLNPAAERDYFDLRERIDENEQQLKGLQDYIRAQCQ 126
 
Name Accession Description Interval E-value
Phage_lysis pfam03245
Bacteriophage Rz lysis protein; This protein is involved in host lysis. This family is not ...
 29-153 1.54e-46

Bacteriophage Rz lysis protein; This protein is involved in host lysis. This family is not considered to be a peptidase according to the MEROPs database. This family Rz and the Rz1 protein (pfam06085) represent a unique example of two genes located in different reading frames in the same nucleotide sequence, which encode different proteins that are both required in the same physiological pathway.


Pssm-ID: 427215  Cd Length: 126  Bit Score: 147.64  E-value: 1.54e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128539    29 NAIAYKVQRDKNARELKLANAAITDMQMRQRDVAALDAKYTKELADAKAENDALRDDVAAGRRRLHIKAVCQS-VREATT 107
Cdd:pfam03245   1 EAAKQQRQVVKDASELRAANAEITDQNARIRAVAALDAKHTKELANAKSENDRLRADVAAGTRRLRINATCPAgVPKATS 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 16128539   108 ASGVDNAASPRLADTAERDYFTLRERLITMQKQLEGTQKYINEQCR 153
Cdd:pfam03245  81 AAGVGDAASARLNPAAERDYFDLRERIDENEQQLKGLQDYIRAQCQ 126
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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