NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|16129589|ref|NP_416148|]
View 

SoxR [2Fe-2S] reducing system protein RsxG [Escherichia coli str. K-12 substr. MG1655]

Protein Classification

electron transport complex subunit G( domain architecture ID 10011734)

electron transport complex subunit G is part of a membrane complex that may be involved in transporting electrons to nitrogenase

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
PRK01908 PRK01908
electron transport complex protein RnfG; Validated
5-206 5.38e-147

electron transport complex protein RnfG; Validated


:

Pssm-ID: 179350  Cd Length: 205  Bit Score: 406.57  E-value: 5.38e-147
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129589    5 IRKHGITLALFAAGSTGLTAAINQMTKTTIAEQASLQQKALFDQVLPAERYNNALAQSCYLVTAPELGK-GEHRVYIAKQ 83
Cdd:PRK01908   1 MRKHGITLALFAALCTGLTAVVNQLTKDTIAEQAALQQKALLDQVIPAERYDNDLQESCYLVTDPALGKdGPHRVYIARK 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129589   84 DDKPVAAVLEATAPDGYSGAIQLLVGADFNGTVLGTRVTEHHETPGLGDKIELRLSDWITHFAGKKISGADDAHWAVKKD 163
Cdd:PRK01908  81 DGKPVAAAIEATAPDGYSGAIQLLVGADFNGTVLGVRVLEHHETPGLGDKIELRISDWITHFSGKKISGENDKHWAVKKD 160
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 16129589  164 GGDFDQFTGATITPRAVVNAVKRAGLYAQTLPAQLSQLPACGE 206
Cdd:PRK01908 161 GGDFDQFTGATITPRAVVNAVKRAALYAQTLPAQLSSLPACGE 203
 
Name Accession Description Interval E-value
PRK01908 PRK01908
electron transport complex protein RnfG; Validated
5-206 5.38e-147

electron transport complex protein RnfG; Validated


Pssm-ID: 179350  Cd Length: 205  Bit Score: 406.57  E-value: 5.38e-147
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129589    5 IRKHGITLALFAAGSTGLTAAINQMTKTTIAEQASLQQKALFDQVLPAERYNNALAQSCYLVTAPELGK-GEHRVYIAKQ 83
Cdd:PRK01908   1 MRKHGITLALFAALCTGLTAVVNQLTKDTIAEQAALQQKALLDQVIPAERYDNDLQESCYLVTDPALGKdGPHRVYIARK 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129589   84 DDKPVAAVLEATAPDGYSGAIQLLVGADFNGTVLGTRVTEHHETPGLGDKIELRLSDWITHFAGKKISGADDAHWAVKKD 163
Cdd:PRK01908  81 DGKPVAAAIEATAPDGYSGAIQLLVGADFNGTVLGVRVLEHHETPGLGDKIELRISDWITHFSGKKISGENDKHWAVKKD 160
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 16129589  164 GGDFDQFTGATITPRAVVNAVKRAGLYAQTLPAQLSQLPACGE 206
Cdd:PRK01908 161 GGDFDQFTGATITPRAVVNAVKRAALYAQTLPAQLSSLPACGE 203
RnfG COG4659
Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfG subunit [Energy production and ...
2-196 7.13e-92

Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfG subunit [Energy production and conversion]; Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfG subunit is part of the Pathway/BioSystem: Na+-translocating Fd:NADH oxidoreductase


Pssm-ID: 443697 [Multi-domain]  Cd Length: 192  Bit Score: 266.69  E-value: 7.13e-92
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129589   2 LKTIRKHGITLALFAAGSTGLTAAINQMTKTTIAEQASLQQKALFDQVLPAERYNNALAQSCYLVTAPELGKGEHRVYIA 81
Cdd:COG4659   1 MKSILKMALILGLIALVAGGLLALVYELTKPPIAANEAEALLAALKQVLPEASFDNDLLADTLTVTDPEGSGGPLTVYRA 80
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129589  82 KQDDKPVAAVLEaTAPDGYSGAIQLLVGADFNGTVLGTRVTEHHETPGLGDKIELRlSDWITHFAGKKISGADDaHWAVK 161
Cdd:COG4659  81 RKGGEPVGYAFE-AAPDGYGGPIKLLVGIDPDGTILGVRVLSHKETPGLGDKIEER-SDWILQFKGKSLDNPDA-RWAVK 157
                       170       180       190
                ....*....|....*....|....*....|....*
gi 16129589 162 KDGGDFDQFTGATITPRAVVNAVKRAGLYAQTLPA 196
Cdd:COG4659 158 KDGGEFDAITGATITSRAVVKAVNRALEFFKEHRA 192
rnfG TIGR01947
electron transport complex, RnfABCDGE type, G subunit; The six subunit complex RnfABCDGE in ...
9-193 6.01e-89

electron transport complex, RnfABCDGE type, G subunit; The six subunit complex RnfABCDGE in Rhodobacter capsulatus encodes an apparent NADH oxidoreductase responsible for electron transport to nitrogenase, necessary for nitrogen fixation. A closely related complex in E. coli, RsxABCDGE (Reducer of SoxR), reduces the 2Fe-2S-containing superoxide sensor SoxR, active as a transcription factor when oxidized. This family of putative NADH oxidoreductase complexes exists in many of the same species as the related NQR, a Na(+)-translocating NADH-quinone reductase, but is distinct. This model describes the A subunit. [Energy metabolism, Electron transport]


Pssm-ID: 273889 [Multi-domain]  Cd Length: 186  Bit Score: 259.21  E-value: 6.01e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129589     9 GITLALFAAGSTGLTAAINQMTKTTIAEQASLQQKALFDQVLPAERYNNALAQSCYLVTAPEL--GKGEHRVYIAKQDDK 86
Cdd:TIGR01947   1 GLLLGLFAAVSAGLLALVNQFTKEQIAEAEAKQQLEALKQVLPQGLYDNDLLESTVPEVDEDLlgLGTILPVYGAKKGGQ 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129589    87 PVAAVLEATAPdGYSGAIQLLVGADFNGTVLGTRVTEHHETPGLGDKIELRLSDWITHFAGKKISGADDAHWAVKKDGGD 166
Cdd:TIGR01947  81 VVAYVLEVSAP-GYSGPIQLLVGIDKDGTILGVRVLSHKETPGLGDKIELRISDWIEGFAGKSLADPDDDHWAVKKDGGQ 159
                         170       180
                  ....*....|....*....|....*..
gi 16129589   167 FDQFTGATITPRAVVNAVKRAGLYAQT 193
Cdd:TIGR01947 160 FDQFTGATITPRAVVNAVKRALRYFKE 186
FMN_bind smart00900
This conserved region includes the FMN-binding site of the NqrC protein as well as the NosR ...
99-187 4.03e-26

This conserved region includes the FMN-binding site of the NqrC protein as well as the NosR and NirI regulatory proteins;


Pssm-ID: 214897 [Multi-domain]  Cd Length: 86  Bit Score: 96.26  E-value: 4.03e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129589     99 GYSGAIQLLVG-ADFNGTVLGTRVTEHHETPGlgDKIELrlSDWITHFAGKKIsgADDAHWAVKK-DGGDFDQFTGATIT 176
Cdd:smart00900   1 GYGGPITVLVTvKDDKGKITGVKVLEHKETPG--DGIDE--PKWIGQFAGKAL--EKLAKEIVKKqSGGDVDAISGATIT 74
                           90
                   ....*....|.
gi 16129589    177 PRAVVNAVKRA 187
Cdd:smart00900  75 SRAVKDAVKRA 85
FMN_bind pfam04205
FMN-binding domain; This conserved region includes the FMN-binding site of the NqrC protein as ...
99-187 1.12e-19

FMN-binding domain; This conserved region includes the FMN-binding site of the NqrC protein as well as the NosR and NirI regulatory proteins. This domain is post-translationally flavinylated that may facilitate electron transfer, and thus, resembles multiheme cytochromes.


Pssm-ID: 461226 [Multi-domain]  Cd Length: 71  Bit Score: 78.81  E-value: 1.12e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129589    99 GYSGAIQLLVGADFNGTVLGTRVTEHHETPGLGDKIELRLSDWIthfagkkisgaddahwavkKDGGDFDQFTGATITPR 178
Cdd:pfam04205   1 GYGGPITVLVGVDGDGTITGIKVLEHSETPGLGIKEQKVKKDKI-------------------EGGQDVDAISGATITSR 61

                  ....*....
gi 16129589   179 AVVNAVKRA 187
Cdd:pfam04205  62 AVVEAVKNA 70
 
Name Accession Description Interval E-value
PRK01908 PRK01908
electron transport complex protein RnfG; Validated
5-206 5.38e-147

electron transport complex protein RnfG; Validated


Pssm-ID: 179350  Cd Length: 205  Bit Score: 406.57  E-value: 5.38e-147
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129589    5 IRKHGITLALFAAGSTGLTAAINQMTKTTIAEQASLQQKALFDQVLPAERYNNALAQSCYLVTAPELGK-GEHRVYIAKQ 83
Cdd:PRK01908   1 MRKHGITLALFAALCTGLTAVVNQLTKDTIAEQAALQQKALLDQVIPAERYDNDLQESCYLVTDPALGKdGPHRVYIARK 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129589   84 DDKPVAAVLEATAPDGYSGAIQLLVGADFNGTVLGTRVTEHHETPGLGDKIELRLSDWITHFAGKKISGADDAHWAVKKD 163
Cdd:PRK01908  81 DGKPVAAAIEATAPDGYSGAIQLLVGADFNGTVLGVRVLEHHETPGLGDKIELRISDWITHFSGKKISGENDKHWAVKKD 160
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 16129589  164 GGDFDQFTGATITPRAVVNAVKRAGLYAQTLPAQLSQLPACGE 206
Cdd:PRK01908 161 GGDFDQFTGATITPRAVVNAVKRAALYAQTLPAQLSSLPACGE 203
RnfG COG4659
Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfG subunit [Energy production and ...
2-196 7.13e-92

Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfG subunit [Energy production and conversion]; Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfG subunit is part of the Pathway/BioSystem: Na+-translocating Fd:NADH oxidoreductase


Pssm-ID: 443697 [Multi-domain]  Cd Length: 192  Bit Score: 266.69  E-value: 7.13e-92
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129589   2 LKTIRKHGITLALFAAGSTGLTAAINQMTKTTIAEQASLQQKALFDQVLPAERYNNALAQSCYLVTAPELGKGEHRVYIA 81
Cdd:COG4659   1 MKSILKMALILGLIALVAGGLLALVYELTKPPIAANEAEALLAALKQVLPEASFDNDLLADTLTVTDPEGSGGPLTVYRA 80
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129589  82 KQDDKPVAAVLEaTAPDGYSGAIQLLVGADFNGTVLGTRVTEHHETPGLGDKIELRlSDWITHFAGKKISGADDaHWAVK 161
Cdd:COG4659  81 RKGGEPVGYAFE-AAPDGYGGPIKLLVGIDPDGTILGVRVLSHKETPGLGDKIEER-SDWILQFKGKSLDNPDA-RWAVK 157
                       170       180       190
                ....*....|....*....|....*....|....*
gi 16129589 162 KDGGDFDQFTGATITPRAVVNAVKRAGLYAQTLPA 196
Cdd:COG4659 158 KDGGEFDAITGATITSRAVVKAVNRALEFFKEHRA 192
rnfG TIGR01947
electron transport complex, RnfABCDGE type, G subunit; The six subunit complex RnfABCDGE in ...
9-193 6.01e-89

electron transport complex, RnfABCDGE type, G subunit; The six subunit complex RnfABCDGE in Rhodobacter capsulatus encodes an apparent NADH oxidoreductase responsible for electron transport to nitrogenase, necessary for nitrogen fixation. A closely related complex in E. coli, RsxABCDGE (Reducer of SoxR), reduces the 2Fe-2S-containing superoxide sensor SoxR, active as a transcription factor when oxidized. This family of putative NADH oxidoreductase complexes exists in many of the same species as the related NQR, a Na(+)-translocating NADH-quinone reductase, but is distinct. This model describes the A subunit. [Energy metabolism, Electron transport]


Pssm-ID: 273889 [Multi-domain]  Cd Length: 186  Bit Score: 259.21  E-value: 6.01e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129589     9 GITLALFAAGSTGLTAAINQMTKTTIAEQASLQQKALFDQVLPAERYNNALAQSCYLVTAPEL--GKGEHRVYIAKQDDK 86
Cdd:TIGR01947   1 GLLLGLFAAVSAGLLALVNQFTKEQIAEAEAKQQLEALKQVLPQGLYDNDLLESTVPEVDEDLlgLGTILPVYGAKKGGQ 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129589    87 PVAAVLEATAPdGYSGAIQLLVGADFNGTVLGTRVTEHHETPGLGDKIELRLSDWITHFAGKKISGADDAHWAVKKDGGD 166
Cdd:TIGR01947  81 VVAYVLEVSAP-GYSGPIQLLVGIDKDGTILGVRVLSHKETPGLGDKIELRISDWIEGFAGKSLADPDDDHWAVKKDGGQ 159
                         170       180
                  ....*....|....*....|....*..
gi 16129589   167 FDQFTGATITPRAVVNAVKRAGLYAQT 193
Cdd:TIGR01947 160 FDQFTGATITPRAVVNAVKRALRYFKE 186
FMN_bind smart00900
This conserved region includes the FMN-binding site of the NqrC protein as well as the NosR ...
99-187 4.03e-26

This conserved region includes the FMN-binding site of the NqrC protein as well as the NosR and NirI regulatory proteins;


Pssm-ID: 214897 [Multi-domain]  Cd Length: 86  Bit Score: 96.26  E-value: 4.03e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129589     99 GYSGAIQLLVG-ADFNGTVLGTRVTEHHETPGlgDKIELrlSDWITHFAGKKIsgADDAHWAVKK-DGGDFDQFTGATIT 176
Cdd:smart00900   1 GYGGPITVLVTvKDDKGKITGVKVLEHKETPG--DGIDE--PKWIGQFAGKAL--EKLAKEIVKKqSGGDVDAISGATIT 74
                           90
                   ....*....|.
gi 16129589    177 PRAVVNAVKRA 187
Cdd:smart00900  75 SRAVKDAVKRA 85
FMN_bind pfam04205
FMN-binding domain; This conserved region includes the FMN-binding site of the NqrC protein as ...
99-187 1.12e-19

FMN-binding domain; This conserved region includes the FMN-binding site of the NqrC protein as well as the NosR and NirI regulatory proteins. This domain is post-translationally flavinylated that may facilitate electron transfer, and thus, resembles multiheme cytochromes.


Pssm-ID: 461226 [Multi-domain]  Cd Length: 71  Bit Score: 78.81  E-value: 1.12e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129589    99 GYSGAIQLLVGADFNGTVLGTRVTEHHETPGLGDKIELRLSDWIthfagkkisgaddahwavkKDGGDFDQFTGATITPR 178
Cdd:pfam04205   1 GYGGPITVLVGVDGDGTITGIKVLEHSETPGLGIKEQKVKKDKI-------------------EGGQDVDAISGATITSR 61

                  ....*....
gi 16129589   179 AVVNAVKRA 187
Cdd:pfam04205  62 AVVEAVKNA 70
NqrC COG2869
Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC [Energy production and ...
108-185 4.60e-08

Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC [Energy production and conversion]; Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC is part of the Pathway/BioSystem: Na+-translocating NADH dehydrogenase


Pssm-ID: 442116  Cd Length: 257  Bit Score: 51.74  E-value: 4.60e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129589 108 VGADFNgTVLGTRVTEHHETPGLGDKIELRlsDWITHFAGKKISGAD-DAHWAVKKDGGD------FDQFTGATITPRAV 180
Cdd:COG2869 156 LEADGN-TVKGLTFYHHGETPGLGAEIENP--KWQAQFVGKKIFDEDgFVAIRVVKGGADpkdeheVDGLSGATLTSNGV 232

                ....*
gi 16129589 181 VNAVK 185
Cdd:COG2869 233 TNMLK 237
PRK05346 PRK05346
Na(+)-translocating NADH-quinone reductase subunit C; Provisional
108-185 2.12e-06

Na(+)-translocating NADH-quinone reductase subunit C; Provisional


Pssm-ID: 235423  Cd Length: 256  Bit Score: 46.76  E-value: 2.12e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129589  108 VGADFNgTVLGTRVTEHHETPGLGDKIELRlsDWITHFAGKKISGaDDAHWAVK------KDGGDF--DQFTGATITPRA 179
Cdd:PRK05346 154 LEPDGN-TVKGLTFYEHGETPGLGGEIENP--QWQAQWVGKKLFD-EQGKPAIKvvkggaSAKDEHgvDGLSGATLTSNG 229

                 ....*.
gi 16129589  180 VVNAVK 185
Cdd:PRK05346 230 VQNSFK 235
nqrC TIGR01938
NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit; This model represents the NqrC ...
115-185 3.27e-05

NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit; This model represents the NqrC subunit of the six-protein, Na(+)-pumping NADH-quinone reductase of a number of marine and pathogenic Gram-negative bacteria. This oxidoreductase complex functions primarily as a sodium ion pump. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273886  Cd Length: 251  Bit Score: 43.15  E-value: 3.27e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129589   115 TVLGTRVTEHHETPGLGDKIElrLSDWITHFAGKKI---SGADDAHWAVKKDGG------DFDQFTGATITPRAVVNAVK 185
Cdd:TIGR01938 162 TVLGITYYQQGETPGLGAEIE--NPEWQAQFVGKKLfdeQGQALALEVVKGNGAsakaehSVDGISGATLTSNGVQESFK 239
NosR COG3901
Transcriptional regulator NosR of nitric oxide reductase [Transcription];
99-189 1.97e-04

Transcriptional regulator NosR of nitric oxide reductase [Transcription];


Pssm-ID: 443108 [Multi-domain]  Cd Length: 713  Bit Score: 41.46  E-value: 1.97e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129589  99 GYSGA-IQLLVGADFNGTVLGTRVTEHHEtP----GLGDKielRLSDWITHFAGKKI--------SGADDAHwavkkdgg 165
Cdd:COG3901  78 GYSGKpINTLVGIDTDGRIVGVKLLKHSE-PilliGIPES---KLRAFIEQYVGLDVkdeievggSRDEGAH-------- 145
                        90       100
                ....*....|....*....|....
gi 16129589 166 DFDQFTGATITPRAVVNAVKRAGL 189
Cdd:COG3901 146 GLDIISGATVTVMVINDSIMRSAL 169
COG3976 COG3976
Uncharacterized conserved protein, contains FMN-binding domain [General function prediction ...
98-187 1.11e-03

Uncharacterized conserved protein, contains FMN-binding domain [General function prediction only];


Pssm-ID: 443175  Cd Length: 116  Bit Score: 37.58  E-value: 1.11e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129589  98 DGYSGAIQLLVGADfNGTVLGTRVTEHHETPGLGDKIELRLSDWIthfagkkisgaddahwaVKKDGGDFDQFTGATITP 177
Cdd:COG3976  39 QGFNGDVTVEVTVS-DGKITDIEVLEHGETPGIGDKAIEELPDEI-----------------VEAQSLDVDAVSGATLTS 100
                        90
                ....*....|
gi 16129589 178 RAVVNAVKRA 187
Cdd:COG3976 101 KAIKEAVEDA 110
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH