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Conserved domains on  [gi|16129841|ref|NP_416403|]
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motility protein B [Escherichia coli str. K-12 substr. MG1655]

Protein Classification

flagellar motor protein MotB( domain architecture ID 11483518)

flagellar motor protein MotB (motility protein B) is required for the rotation of the flagellar motor

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
motB PRK09041
motility protein MotB;
1-308 0e+00

motility protein MotB;


:

Pssm-ID: 236365 [Multi-domain]  Cd Length: 317  Bit Score: 550.32  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841    1 MKNQAHPIIVVKRRKAKSHGAAHGSWKIAYADFMTAMMAFFLVMWLISISSPKELIQIAEYFRTPLATAVTGGDRISNSE 80
Cdd:PRK09041   1 MKKENHPPIVVKRVKKKGHGHHGGSWKIAYADFMTAMMAFFLVMWLLSSSTPEQLIGIAEYFRTPLKVALTGGDRSSDST 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841   81 SPIPGGGDDYTQSQGEVNKQPNIEEL----KKRMEQSRLRKLRGDLDQLIESDPKLRALRPHLKIDLVQEGLRIQIIDSQ 156
Cdd:PRK09041  81 SPIPGGGDDITQQDGEVNKQPNIAELaqgeKERREQERLEKLKQELDQAIESNPKLRQFKPQLLIDLTQEGLRIQIVDSQ 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841  157 NRPMFRTGSADVEPYMRDILRAIAPVLNGIPNRISLSGHTDDFPYASGEKGYSNWELSADRANASRRELMVGGLDSGKVL 236
Cdd:PRK09041 161 NRPMFATGSAEVEPYMRDILREIAPVLNDVPNRISLSGHTDATPYANGEKGYSNWELSADRANASRRELVAGGMDEGKVL 240

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 16129841  237 RVVGMAATMRLSDRGPDDAVNRRISLLVLNKQAEQAILHENAES-----QNEPVSALEKPEVAPQVSVPTMPSAEPR 308
Cdd:PRK09041 241 RVVGLASTMLLDKKDPLNPVNRRISIVVLNKKAEEAILHENAESvalsaQNEPVSALEAPAAAPAASVPAAPAAEPR 317
 
Name Accession Description Interval E-value
motB PRK09041
motility protein MotB;
1-308 0e+00

motility protein MotB;


Pssm-ID: 236365 [Multi-domain]  Cd Length: 317  Bit Score: 550.32  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841    1 MKNQAHPIIVVKRRKAKSHGAAHGSWKIAYADFMTAMMAFFLVMWLISISSPKELIQIAEYFRTPLATAVTGGDRISNSE 80
Cdd:PRK09041   1 MKKENHPPIVVKRVKKKGHGHHGGSWKIAYADFMTAMMAFFLVMWLLSSSTPEQLIGIAEYFRTPLKVALTGGDRSSDST 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841   81 SPIPGGGDDYTQSQGEVNKQPNIEEL----KKRMEQSRLRKLRGDLDQLIESDPKLRALRPHLKIDLVQEGLRIQIIDSQ 156
Cdd:PRK09041  81 SPIPGGGDDITQQDGEVNKQPNIAELaqgeKERREQERLEKLKQELDQAIESNPKLRQFKPQLLIDLTQEGLRIQIVDSQ 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841  157 NRPMFRTGSADVEPYMRDILRAIAPVLNGIPNRISLSGHTDDFPYASGEKGYSNWELSADRANASRRELMVGGLDSGKVL 236
Cdd:PRK09041 161 NRPMFATGSAEVEPYMRDILREIAPVLNDVPNRISLSGHTDATPYANGEKGYSNWELSADRANASRRELVAGGMDEGKVL 240

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 16129841  237 RVVGMAATMRLSDRGPDDAVNRRISLLVLNKQAEQAILHENAES-----QNEPVSALEKPEVAPQVSVPTMPSAEPR 308
Cdd:PRK09041 241 RVVGLASTMLLDKKDPLNPVNRRISIVVLNKKAEEAILHENAESvalsaQNEPVSALEAPAAAPAASVPAAPAAEPR 317
MotB COG1360
Flagellar motor protein MotB [Cell motility];
17-272 1.15e-57

Flagellar motor protein MotB [Cell motility];


Pssm-ID: 440971 [Multi-domain]  Cd Length: 174  Bit Score: 183.12  E-value: 1.15e-57
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841  17 KSHGAAHGSWKIAYADFMTAMMAFFLVMWLISisspkeliqiaeyfrtplatavtggdrisnsespipgggddytqsqge 96
Cdd:COG1360   1 EEEGHHGGAWLVTYADLMTLLLAFFVLLWALS------------------------------------------------ 32

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841  97 vnkqpnieelkkrmeqSRLRKLrgdldqliesdpklrALRPHLKIDLVQEGLRIQIIDsqnRPMFRTGSADVEPYMRDIL 176
Cdd:COG1360  33 ----------------SALEEN---------------LLSGQVEVRITEEGLVIEIQD---RVLFDSGSAELTPEGRELL 78

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841 177 RAIAPVLNGIPNRISLSGHTDDFPYaSGEKGYSNWELSADRANASRRELMVGGLDSGKvLRVVGMAATMRL--SDRGPDD 254
Cdd:COG1360  79 DKIAAVLAEVPNRIRVEGHTDNVPI-STARFPSNWELSAARAAAVVRYLIEGGVPPER-LSAVGYGDTRPLapNDTPEGR 156

                       250
                ....*....|....*...
gi 16129841 255 AVNRRISLLVLNKQAEQA 272
Cdd:COG1360 157 ARNRRVEIVILRRAAEEA 174
MotB_plug pfam13677
Membrane MotB of proton-channel complex MotA/MotB; This is the MotB member of the E.coli MotA ...
 12-66 9.29e-23

Membrane MotB of proton-channel complex MotA/MotB; This is the MotB member of the E.coli MotA/MotB proton-channel complex that forms the stator of the bacterial membrane flagellar motor. Key residues act as a plug to prevent premature proton flow. The plug is in the periplasm just C-terminal to the MotB TM, consisting of an amphipathic alpha helix flanked by Pro-52 and Pro-65, eg in Swiss:D3V2T1. In addition to the Pro residues, Ile-58, Tyr-61, and Phe 62 are also essential for plug function.


Pssm-ID: 463955 [Multi-domain]  Cd Length: 57  Bit Score: 89.12  E-value: 9.29e-23
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 16129841    12 KRRKAKSHGAAHGSWKIAYADFMTAMMAFFLVMWLISISSPKELIQIAEYFRTPL 66
Cdd:pfam13677   3 KKKEPEHEGGHGERWLVTYADLMTLLLAFFVLLYSMSSVDEKKFQQIAESFQDAF 57
OmpA_C-like cd07185
Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; ...
 161-264 3.43e-17

Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; OmpA-like domains (named after the C-terminal domain of Escherichia coli OmpA protein) have been shown to non-covalently associate with peptidoglycan, a network of glycan chains composed of disaccharides, which are crosslinked via short peptide bridges. Well-studied members of this family include the Escherichia coli outer membrane protein OmpA, the Escherichia coli lipoprotein PAL, Neisseria meningitdis RmpM, which interact with the outer membrane, as well as the Escherichia coli motor protein MotB, and the Vibrio flagellar motor proteins PomB and MotY, which interact with the inner membrane.


Pssm-ID: 143586 [Multi-domain]  Cd Length: 106  Bit Score: 75.67  E-value: 3.43e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841 161 FRTGSADVEPYMRDILRAIAPVLNGIPN-RISLSGHTDDfpyaSGEKGYsNWELSADRANASRRELMVGGLDSGKvLRVV 239
Cdd:cd07185   6 FDFGSAELTPEAKPLLDKLAEVLKKNPDaKIRIEGHTDS----RGSDAY-NQELSERRAEAVADYLVSKGVDASR-ITAV 79

                        90       100
                ....*....|....*....|....*..
gi 16129841 240 GMAATMRLS--DRGPDDAVNRRISLLV 264
Cdd:cd07185  80 GYGESRPIAsnDTEEGRAKNRRVEIVI 106
 
Name Accession Description Interval E-value
motB PRK09041
motility protein MotB;
1-308 0e+00

motility protein MotB;


Pssm-ID: 236365 [Multi-domain]  Cd Length: 317  Bit Score: 550.32  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841    1 MKNQAHPIIVVKRRKAKSHGAAHGSWKIAYADFMTAMMAFFLVMWLISISSPKELIQIAEYFRTPLATAVTGGDRISNSE 80
Cdd:PRK09041   1 MKKENHPPIVVKRVKKKGHGHHGGSWKIAYADFMTAMMAFFLVMWLLSSSTPEQLIGIAEYFRTPLKVALTGGDRSSDST 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841   81 SPIPGGGDDYTQSQGEVNKQPNIEEL----KKRMEQSRLRKLRGDLDQLIESDPKLRALRPHLKIDLVQEGLRIQIIDSQ 156
Cdd:PRK09041  81 SPIPGGGDDITQQDGEVNKQPNIAELaqgeKERREQERLEKLKQELDQAIESNPKLRQFKPQLLIDLTQEGLRIQIVDSQ 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841  157 NRPMFRTGSADVEPYMRDILRAIAPVLNGIPNRISLSGHTDDFPYASGEKGYSNWELSADRANASRRELMVGGLDSGKVL 236
Cdd:PRK09041 161 NRPMFATGSAEVEPYMRDILREIAPVLNDVPNRISLSGHTDATPYANGEKGYSNWELSADRANASRRELVAGGMDEGKVL 240

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 16129841  237 RVVGMAATMRLSDRGPDDAVNRRISLLVLNKQAEQAILHENAES-----QNEPVSALEKPEVAPQVSVPTMPSAEPR 308
Cdd:PRK09041 241 RVVGLASTMLLDKKDPLNPVNRRISIVVLNKKAEEAILHENAESvalsaQNEPVSALEAPAAAPAASVPAAPAAEPR 317
motB PRK12799
flagellar motor protein MotB; Reviewed
 1-307 1.66e-169

flagellar motor protein MotB; Reviewed


Pssm-ID: 183756 [Multi-domain]  Cd Length: 421  Bit Score: 476.90  E-value: 1.66e-169
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841    1 MKNQAHPIIVVKRRKaKSHGAAH--GSWKIAYADFMTAMMAFFLVMWLISISSPKELIQIAEYFRTPLATAVTGGDRISN 78
Cdd:PRK12799   1 MKHQNHPVILVKKRK-TKHGAAHygGSWKIAYADFMTAMMAFFLVMWLLAVSSPQELTQIAEYFRTPLKVALTSGDKSSS 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841   79 SESPIPGGGDDYTQSQGEVNKQPNIEElkKRMEQSRLRKLRGDLDQLIESDPKLRALRPHLKIDLVQEGLRIQIIDSQNR 158
Cdd:PRK12799  80 STSPIPGGGDDPTQQVGEVRKQINSEE--SRQEIHRLNKLREKLDQLIESDPRLKALRPHLLINMMDEGLRIQIIDSQNR 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841  159 PMFRTGSADVEPYMRDILRAIAPVLNGIPNRISLSGHTDDFPYASGEKGYSNWELSADRANASRRELMVGGLDSGKVLRV 238
Cdd:PRK12799 158 PMFKMGSAQVEPYMRDILRAIAPILNDIPNKLSLSGHTDDLPYARGERGYSNWELSADRANASRRELLAGGLDEGKILRV 237

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 16129841  239 VGMAATMRLSDRGPDDAVNRRISLLVLNKQAEQAILHENAESQNEPVSALE----------KPEVAPQVSVPTMPSAEP 307
Cdd:PRK12799 238 VGMASTMRLKEQASDDPVNRRISILVLNKQSQHDIEHENLDNRALDIEKATglkqidthgtVPVAAVTPSSAVTQSSAI 316
MotB COG1360
Flagellar motor protein MotB [Cell motility];
17-272 1.15e-57

Flagellar motor protein MotB [Cell motility];


Pssm-ID: 440971 [Multi-domain]  Cd Length: 174  Bit Score: 183.12  E-value: 1.15e-57
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841  17 KSHGAAHGSWKIAYADFMTAMMAFFLVMWLISisspkeliqiaeyfrtplatavtggdrisnsespipgggddytqsqge 96
Cdd:COG1360   1 EEEGHHGGAWLVTYADLMTLLLAFFVLLWALS------------------------------------------------ 32

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841  97 vnkqpnieelkkrmeqSRLRKLrgdldqliesdpklrALRPHLKIDLVQEGLRIQIIDsqnRPMFRTGSADVEPYMRDIL 176
Cdd:COG1360  33 ----------------SALEEN---------------LLSGQVEVRITEEGLVIEIQD---RVLFDSGSAELTPEGRELL 78

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841 177 RAIAPVLNGIPNRISLSGHTDDFPYaSGEKGYSNWELSADRANASRRELMVGGLDSGKvLRVVGMAATMRL--SDRGPDD 254
Cdd:COG1360  79 DKIAAVLAEVPNRIRVEGHTDNVPI-STARFPSNWELSAARAAAVVRYLIEGGVPPER-LSAVGYGDTRPLapNDTPEGR 156

                       250
                ....*....|....*...
gi 16129841 255 AVNRRISLLVLNKQAEQA 272
Cdd:COG1360 157 ARNRRVEIVILRRAAEEA 174
PRK06778 PRK06778
hypothetical protein; Validated
 10-269 1.74e-49

hypothetical protein; Validated


Pssm-ID: 235860 [Multi-domain]  Cd Length: 289  Bit Score: 166.26  E-value: 1.74e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841   10 VVKRRKAKSHGAAHGS-WKIAYADFMTAMMAFFLVMWLISISSPKELIQIAEYFRTplATAVTGG-----DRISNSESPI 83
Cdd:PRK06778   5 IIKRANRKKHHVRHSGaWKVAFADFTLAMMALFMVLWIVNSVSKSERESIIAALHG--QSIFNGGglsplNKISPSHPPK 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841   84 PGGGDDYTQSQGEVnKQPN--IEELKKRMeqsrlRKLRGDLDQLIESDPKLRALRPHLKIDLVQEGLRIQIIDSQNRPMF 161
Cdd:PRK06778  83 PATVAVPEETEKKA-RDVNekTALLKKKS-----ATELGELATSINTIARDAHMEANLEMEIVPQGLRVLIKDDQNRNMF 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841  162 RTGSADVEPYMRDILRAIAPVLNGIPNRISLSGHTDDFPYASgeKGYSNWELSADRANASRRELMVGGLDSGKVLRVVGM 241
Cdd:PRK06778 157 ERGSAQIMPFFKTLLVELAPVFDSLDNKIIITGHTDAMAYKN--NIYNNWNLSGDRALSARRVLEEAGMPEDKVMQVSAM 234

                        250       260
                 ....*....|....*....|....*...
gi 16129841  242 AATMRLSDRGPDDAVNRRISLLVLNKQA 269
Cdd:PRK06778 235 ADQMLLDAKNPQSAGNRRIEIMVLTKSA 262
motB PRK05996
MotB family protein;
6-268 5.06e-35

MotB family protein;


Pssm-ID: 235665 [Multi-domain]  Cd Length: 423  Bit Score: 131.36  E-value: 5.06e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841    6 HPIIVVKRRKAKSHGAAH-GSWKIAYADFMTAMMAFFLVMWLISISSPKELIQIAEYF---------------------- 62
Cdd:PRK05996  11 NEIIIVRRGGDDDHEGHHgGVWKIAYADFMTAMMAFFLVMWLINAANEETKAAVASYFnpikltdrkpsekglkdpvdga 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841   63 ---------------RTPLATAVTG-------GDRISNSE-------------------------------SPIPG---- 85
Cdd:PRK05996  91 egeqkpgkskfeedqRVEGSSAVTGddttrtsGDQTNYSEadlfrnpyavlaeiaqevgqqanvsakgdggAAQSGpatg 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841   86 --GGDDY--------------------TQSQGEVNKQPNIEE----LKKRMEQ------------SRLRKLRGDLDQLIE 127
Cdd:PRK05996 171 adGGEAYrdpfdpdfwskqvevttagdLLPPGQAREQAQGAKsataAPATVPQaaplpqaqpkkaATEEELIADAKKAAT 250

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841  128 SDPK----------------------------------LRALRPHLKIDLVQEGLRIQIIDSQNRPMFRTGSADVEPYMR 173
Cdd:PRK05996 251 GEPAanaakaakpepmpddqqkeaeqlqaaiaqaiggvAGKLAEGVTVTPVEGGLLISLTDQVDYGMFAIGSAVPRAELV 330

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841  174 DILRAIAPVLNGIPNRISLSGHTDDFPYASGEkgYSNWELSADRANASRRELMVGGLDSGKVLRVVGMAatmrlsDRGPD 253
Cdd:PRK05996 331 LAMEKIGQLLAERPGAVIIRGHTDARPFKSAT--YDNWRLSTARAQSAYYMLVRGGLDEKRIEQVEGFA------DRRPK 402

                        410       420
                 ....*....|....*....|.
gi 16129841  254 D------AVNRRISLLVLNKQ 268
Cdd:PRK05996 403 LpndpnaAANRRIEILIQSKQ 423
PRK09038 PRK09038
flagellar motor protein MotD; Reviewed
 12-305 1.50e-26

flagellar motor protein MotD; Reviewed


Pssm-ID: 181618 [Multi-domain]  Cd Length: 281  Bit Score: 105.48  E-value: 1.50e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841   12 KRRKAKSHGAaHGSWKIAYADFMTAMMAFFLVMWliSISSPKEliqiAEYFRtpLATAVTGGDR-ISNSESPIPgGGDDY 90
Cdd:PRK09038   4 RRKHHEEHEN-HERWLVSYADFITLLFAFFVVMY--AISSVNE----GKYKV--LSEALTGAFNgPSRSMKPIP-IGKEQ 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841   91 TQSQGEVNKQPNIEELKKRMEQSRLRKLRGDLDQ----LIESDpKLRALRPHLkidlvqeGLRIQIIDSQnrpMFRTGSA 166
Cdd:PRK09038  74 PKTTQPARPLVIDSEQPDARAQDQLKTIADDLRKalgpLIESG-QVTVRRNEL-------WIEIEINSSL---LFGSGDA 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841  167 DVEPYMRDILRAIAPVLNGIPNRISLSGHTDDFPYASGEkgY-SNWELSADRANASRRELMVGGLDSGKvLRVVGMAATM 245
Cdd:PRK09038 143 MLSDQAFAILEKVAEVLKPAPNPIHVEGFTDNVPIATAQ--FpSNWELSAARAASVVRLLADDGVAPSR-LAAVGYGEFQ 219

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 16129841  246 RLSDRGPDD--AVNRRISLLVLNKQAEQAILHENAESQNEPVSALeKPEVAPQVSVPTMPSA 305
Cdd:PRK09038 220 PVADNDTAEgrARNRRVVLVILRNLDVRRSLTPVGSANATPDAAL-RRAGTQAAPATAKTDS 280
motB PRK07734
flagellar motor protein MotB; Reviewed
 13-218 1.63e-26

flagellar motor protein MotB; Reviewed


Pssm-ID: 236080 [Multi-domain]  Cd Length: 259  Bit Score: 104.82  E-value: 1.63e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841   13 RRKAKSHGAAH--GSWKIAYADFMTAMMAFFLVMWLISISSPKELIQIAEYFRtplaTAVTGGDRISNSESPI----PGG 86
Cdd:PRK07734   4 RKKKKKKHEEHidESWLIPYADLLTLLLALFIVLFAMSSIDAAKFKQMAVAFN----SEFAGGTGVKDFLSDQkpedEKE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841   87 GDDYTQSQGEVNKQPNIEELKKRmEQSRLRKLRGDLDQLIESdpklRALRPHLKIDLVQEGLRIQIIDSQnrpMFRTGSA 166
Cdd:PRK07734  80 LSASSLEAEQAKKKEEAEAKKKK-EMEELKAVQKKIDQYIKE----KQLSSSLQTKLTEEGLLITILDNI---LFDSGKA 151

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 16129841  167 DVEPYMRDILRAIAPVLNGIPNR-ISLSGHTDDFPYASgEKGYSNWELSADRA 218
Cdd:PRK07734 152 DVRLEDLPLAKEISNLLVSNPPRnITISGHTDNVPIAN-AQFASNWELSVMRA 203
motB PRK08944
flagellar motor protein MotB; Reviewed
 26-285 1.31e-23

flagellar motor protein MotB; Reviewed


Pssm-ID: 236356 [Multi-domain]  Cd Length: 302  Bit Score: 98.16  E-value: 1.31e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841   26 WKIAYADFMTAMMAFFLVmwLISIS------------------------SPKElIQ-----IAEYFR------------- 63
Cdd:PRK08944  17 WLATFADLMSLLMCFFVL--LLSFSemdvlkfkqiagsmkfafgvqnkiEVKD-IPkgtsiIAQEFRpgrpeptpievim 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841   64 --TPLATAVTGGDRISNSESP---------IPGGGDDYTQSQGEVNKQPNIEELKKRMEQsrlrKLRGDL-DQLIEsdpk 131
Cdd:PRK08944  94 qqTIDMTQQTLEFQAGESDSAggtqqqrgkQRGGEASAEVKAEKAAAQEQIEDLVKKLAQ----QLEKEIeDGAIE---- 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841  132 lralrphlkidLVQEGLRIqIIDSQNRPMFRTGSADVEPYMRDILRAIAPVLNGIPNRISLSGHTDDFPyASGEKGYSNW 211
Cdd:PRK08944 166 -----------IESLGQQI-IIRIREKGSFPSGSAFLQPKFKPVVRKIGELLKDVPGIITVSGHTDNVP-ISSELYRSNW 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841  212 ELSADRANASRRELM-VGGLDSGKvLRVVGMAATMrlsDRGPDD-----AVNRRIsllvlnkqaEQAILHENA-ESQNEP 284
Cdd:PRK08944 233 DLSSARAVAVAHELLkVKGFDPQR-LKVVGMADTQ---PLVPNDtaenrARNRRV---------EIIIEQGKAkESDEIP 299


                 .
gi 16129841  285 V 285
Cdd:PRK08944 300 V 300
MotB_plug pfam13677
Membrane MotB of proton-channel complex MotA/MotB; This is the MotB member of the E.coli MotA ...
 12-66 9.29e-23

Membrane MotB of proton-channel complex MotA/MotB; This is the MotB member of the E.coli MotA/MotB proton-channel complex that forms the stator of the bacterial membrane flagellar motor. Key residues act as a plug to prevent premature proton flow. The plug is in the periplasm just C-terminal to the MotB TM, consisting of an amphipathic alpha helix flanked by Pro-52 and Pro-65, eg in Swiss:D3V2T1. In addition to the Pro residues, Ile-58, Tyr-61, and Phe 62 are also essential for plug function.


Pssm-ID: 463955 [Multi-domain]  Cd Length: 57  Bit Score: 89.12  E-value: 9.29e-23
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 16129841    12 KRRKAKSHGAAHGSWKIAYADFMTAMMAFFLVMWLISISSPKELIQIAEYFRTPL 66
Cdd:pfam13677   3 KKKEPEHEGGHGERWLVTYADLMTLLLAFFVLLYSMSSVDEKKFQQIAESFQDAF 57
OmpA_C-like cd07185
Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; ...
 161-264 3.43e-17

Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; OmpA-like domains (named after the C-terminal domain of Escherichia coli OmpA protein) have been shown to non-covalently associate with peptidoglycan, a network of glycan chains composed of disaccharides, which are crosslinked via short peptide bridges. Well-studied members of this family include the Escherichia coli outer membrane protein OmpA, the Escherichia coli lipoprotein PAL, Neisseria meningitdis RmpM, which interact with the outer membrane, as well as the Escherichia coli motor protein MotB, and the Vibrio flagellar motor proteins PomB and MotY, which interact with the inner membrane.


Pssm-ID: 143586 [Multi-domain]  Cd Length: 106  Bit Score: 75.67  E-value: 3.43e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841 161 FRTGSADVEPYMRDILRAIAPVLNGIPN-RISLSGHTDDfpyaSGEKGYsNWELSADRANASRRELMVGGLDSGKvLRVV 239
Cdd:cd07185   6 FDFGSAELTPEAKPLLDKLAEVLKKNPDaKIRIEGHTDS----RGSDAY-NQELSERRAEAVADYLVSKGVDASR-ITAV 79

                        90       100
                ....*....|....*....|....*..
gi 16129841 240 GMAATMRLS--DRGPDDAVNRRISLLV 264
Cdd:cd07185  80 GYGESRPIAsnDTEEGRAKNRRVEIVI 106
motB PRK08457
flagellar motor protein MotB; Reviewed
 26-264 1.24e-14

flagellar motor protein MotB; Reviewed


Pssm-ID: 181435 [Multi-domain]  Cd Length: 257  Bit Score: 72.06  E-value: 1.24e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841   26 WKIAYADFMTAMMAFFLVMWLISISSPK-------ELIQIAEYfrtplaTAVTGGDRISNSESPIPGGGDDYTqSQGEVN 98
Cdd:PRK08457  16 WAVPYADFLSLLLALFIALYAISAVNKAkvealktEFIKIFDY------TAKPEVKQPVKVIPPDSGDAEEEM-DELKSL 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841   99 KQPNIEELKkrmEQSRLRKLRGDLDQLIESdpklralrphlkidlvqeglriQIIDSQNRPMFRTGSADV-EPYMRDILR 177
Cdd:PRK08457  89 KASQNTQQE---TIERRKGEGGALDQIDNG----------------------IALKLPSKLLFENGSAEIiNADMMDYLK 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841  178 AIAPVLNGIPNRIS--LSGHTDDFPyASGEKGYSNWELSADRANASRRELMVGGLDSgKVLRVVGMAATMRLSdrGPDDA 255
Cdd:PRK08457 144 RIAKIITKLPKQVKinVRGYTDNSP-LNKSRYKDHYELAAARAYNVMKVLIQYGINP-NRLSFSSYGSNNPIA--PNDSL 219


                 ....*....
gi 16129841  256 VNRRISLLV 264
Cdd:PRK08457 220 ENRLKNNRV 228
PRK06925 PRK06925
flagellar motor protein MotB;
12-218 7.70e-14

flagellar motor protein MotB;


Pssm-ID: 235887 [Multi-domain]  Cd Length: 230  Bit Score: 69.41  E-value: 7.70e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841   12 KRRKAKSHGAAhgSWKIAYADFMTAMMAFFLVMWLISISSPKELIQIAEYFRTplatavtggdrisnsespipGGGDDYT 91
Cdd:PRK06925   3 RRKRQQSKGSP--KWMVTFSDLITLILVFFILLFSMSQIDAQKFKAAVESFQQ--------------------RGSLGFL 60

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841   92 QSQGEVNKQPNIEELKKRMEQsrlrklrgDLDQLIESdpklraLRPHLKIDLVQEGL------RIQIIDSQNRPMFRTGS 165
Cdd:PRK06925  61 PSAIEFENPAESSEDEEKQED--------QLDELLKK------VNEYIEENELKSVItakrdeRGVVLVLQEAVLFETGE 126

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 16129841  166 ADVEPYMRDILRAIAPVLNGIPNRISLSGHTDDFPyASGEKGYSNWELSADRA 218
Cdd:PRK06925 127 ADILKQAEPFLHKIGVLLSTIPNDIKVEGHTDSRP-ISTYRYPSNWELSAARA 178
OmpA pfam00691
OmpA family; The Pfam entry also includes MotB and related proteins which are not included in ...
 161-259 2.84e-13

OmpA family; The Pfam entry also includes MotB and related proteins which are not included in the Prosite family.


Pssm-ID: 425825 [Multi-domain]  Cd Length: 95  Bit Score: 64.69  E-value: 2.84e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841   161 FRTGSADVEPYMRDILRAIAPVLNGIPNR--ISLSGHTDDFPYASGekgysNWELSADRANASRRELMVGGLDSGKVLrV 238
Cdd:pfam00691   1 FDPGSSQLTPKAKATLDEIADLLKFPELKntITIEGHTDTVGSAAY-----NWELSQRRAEAVRRYLVNFGVPPSRIS-V 74

                          90       100
                  ....*....|....*....|.
gi 16129841   239 VGMAATMRLSDRGPDDAVNRR 259
Cdd:pfam00691  75 VGYGATKPITDNKTPEGRARN 95
OmpA COG2885
Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins [Cell wall ...
 161-267 2.94e-12

Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442131 [Multi-domain]  Cd Length: 294  Bit Score: 65.96  E-value: 2.94e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841 161 FRTGSADVEPYMRDILRAIAPVLNGIPN-RISLSGHTDdfpyASGEKGYsNWELSADRANASRRELMVGGLDSGKvLRVV 239
Cdd:COG2885 191 FDFDSAELTPEAKAALDELAALLKENPDlRIEIEGHTD----SRGSDAY-NLALSERRAEAVKDYLVSKGIPASR-ITAV 264

                        90       100       110
                ....*....|....*....|....*....|
gi 16129841 240 GMAATMRLSDRGPDD--AVNRRISLLVLNK 267
Cdd:COG2885 265 GYGESRPVASNDTEEgrAKNRRVEIVVLKK 294
motB PRK06667
flagellar motor protein MotB; Validated
 12-265 1.84e-11

flagellar motor protein MotB; Validated


Pssm-ID: 180652 [Multi-domain]  Cd Length: 252  Bit Score: 62.89  E-value: 1.84e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841   12 KRRKAKSHGAAHGSWKIAYADFMTAMMAFFLVMWliSISSPKE-LIQIaeyfrtpLATAVTGGDrisnsesPIPGGgddY 90
Cdd:PRK06667   4 RKKKCPKCIQGAPEYMLTYGDMVTLLLCFFVMLF--TTNDVDEnVLQI-------ISASFTGTG-------FFKGG---Q 64

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841   91 TQSQGEVNKQPN-IEELKKRMEQSRLRKLRGDLDQLIEsdPKLRALrphlKIdLVQEGLRIQIIDSQNRPMFRTGSADVE 169
Cdd:PRK06667  65 TLSKGKLSELGNsIMSLPSTEKGKQLSQAKKNASSLFK--PEIQSN----KV-AVTEDERGLVISLASDAFFYPGSAEVK 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841  170 -PYMRDILRAIAPVLNGIPN---RISLSGHTDDFPyASGEKGY-SNWELSADRA-NASRRELMVGGLDSGKvLRVVGMAA 243
Cdd:PRK06667 138 lEENRETLQKIASFIGFLDLagrNFRIEGHTDNVD-VNPEGPWkSNWELSGARAvNMLEYILNYGDQSESW-FQVSGFAG 215

                        250       260
                 ....*....|....*....|....
gi 16129841  244 TMRL-SDRGPD-DAVNRRISLLVL 265
Cdd:PRK06667 216 SRPLaTEDTPEgRAYNRRIDIVIL 239
PRK06742 PRK06742
flagellar motor protein MotS; Reviewed
 26-264 2.94e-10

flagellar motor protein MotS; Reviewed


Pssm-ID: 102525 [Multi-domain]  Cd Length: 225  Bit Score: 59.31  E-value: 2.94e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841   26 WKIAYADFMTAMMAFFLVMWLISISSPKELIQIAEYFrtplatavTGGDRISNS--ESPIPgggddytqsqgEVNKQPNI 103
Cdd:PRK06742  12 WMTTFTDLTMLLLTFFVLLVATSKQDAVKLSKMLEKF--------SDTEQVDAKvmENTIP-----------DISHEKND 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841  104 EEL--KKRMEQsRLRKLRGDLDQLIESdpklralrphlKIDLVQE--GLRIQIIDSQnrpMFRTGSADVEPYMRDILRAI 179
Cdd:PRK06742  73 EKMisKKRMDE-LYKKLKAYVDNNGIS-----------QVNVYREdtGVSVVIVDNL---IFDTGDANVKPEAKEIISQL 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841  180 APVLNGIPNRISLSGHTDDFPYASgEKGYSNWELSADR-ANASRRELMVGGLDSgKVLRVVGMAATMRL-SDRGPDD-AV 256
Cdd:PRK06742 138 VGFFQSVPNPIVVEGHTDSRPIHN-DKFPSNWELSSARaANMIHHLIEVYNVDD-KRLAAVGYADTKPVvPNDSPQNwEK 215


                 ....*...
gi 16129841  257 NRRISLLV 264
Cdd:PRK06742 216 NRRVVIYI 223
PRK07033 PRK07033
DotU family type VI secretion system protein;
160-264 1.54e-07

DotU family type VI secretion system protein;


Pssm-ID: 180801 [Multi-domain]  Cd Length: 427  Bit Score: 52.36  E-value: 1.54e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841  160 MFRTGSADVEPYMRDILRAIAPVLNGIPNRISLSGHTDDFPYASGeKGYSNWELSADRANASrRELMVGGLDSGKVLRVV 239
Cdd:PRK07033 317 LFASASTSVRDRYQPVLARVADALNQVKGNVLVTGYSDNVPIRTA-RFPSNWELSQARAQAV-RALLAARLGQPERVTAE 394

                         90       100       110
                 ....*....|....*....|....*....|..
gi 16129841  240 GMAATMRLSdrgPDD-----AVNRR--ISLLV 264
Cdd:PRK07033 395 GRGDSDPVA---PNDsaenrARNRRveITLLV 423
PRK09039 PRK09039
peptidoglycan -binding protein;
145-262 3.92e-06

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 47.65  E-value: 3.92e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841  145 QEGLRIqIIDS---QNRPMFRTGSADVEPYMRDILRAIAPVLN----GIPNRIS----LSGHTDDFPYASGEKGYSNWEL 213
Cdd:PRK09039 210 REGIRI-VGDRfvfQSEVLFPTGSAELNPEGQAEIAKLAAALIelakEIPPEINwvlrVDGHTDNVPLSGTGRFRDNWEL 288

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 16129841  214 SADRANASRRELMVGGLDSGKvLRVVGMAATMRLSDRGPDDAV--NRRISL 262
Cdd:PRK09039 289 SSARAISVVKFLIALGVPADR-LAAAGFGEFQPLDPGDTPEARarNRRIEL 338
PRK08126 PRK08126
hypothetical protein; Provisional
 160-264 7.42e-06

hypothetical protein; Provisional


Pssm-ID: 236157 [Multi-domain]  Cd Length: 432  Bit Score: 47.00  E-value: 7.42e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841  160 MFRTGSADVEPYMRDILRAIAPVLNGIPNRISLSGHTDDFPYASGEKGySNWELSADRANASRRELMVGGLDSGKvLRVV 239
Cdd:PRK08126 326 MFVPGQATVNPAMGPLIAKIAREIARVGGKVTVTGHTDNQPIRSAQFA-SNLVLSEKRAAQVAQMLQSAGVPASR-LEAV 403

                         90       100
                 ....*....|....*....|....*..
gi 16129841  240 GMAATMRLSDRGPDD--AVNRRISLLV 264
Cdd:PRK08126 404 GKGDAQPVADNRTPQgrAQNRRVEITV 430
PRK09040 PRK09040
hypothetical protein; Provisional
 160-235 3.40e-04

hypothetical protein; Provisional


Pssm-ID: 181620 [Multi-domain]  Cd Length: 214  Bit Score: 41.16  E-value: 3.40e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129841  160 MFRTGSADVEPYMRDILRAIAPVLNGIPNR----ISLSGHTDDFPYASGEKGYS-NWELSADRANASRRELMVGGLDSGK 234
Cdd:PRK09040  91 LFALNSDQLQPEGRELLKSLAGPLAAYLRArdeiLMVSGFTDDQPVRAGNRRFAdNWELSAQRALTVTRALIDAGVPASS 170


                 .
gi 16129841  235 V 235
Cdd:PRK09040 171 V 171
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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