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Conserved domains on  [gi|16129953|ref|NP_416516|]
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putative thiosulfate sulfurtransferase [Escherichia coli str. K-12 substr. MG1655]

Protein Classification

sulfurtransferase TusA family protein( domain architecture ID 10001403)

sulfurtransferase TusA family protein similar to sulfurtransferase TusA, which interacts with cysteine desulfurase IscS and acts as the first member in a sulfur relay mechanism, transfering sulfur to the TusBCD complex

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TusA_like_YeeD NF041048
thiosulfate utilization sulfurtransferase TsuB/YeeD; YeeD (TsuB) is a TusA family putative ...
 3-74 9.68e-45

thiosulfate utilization sulfurtransferase TsuB/YeeD; YeeD (TsuB) is a TusA family putative sulfurtransferase associated with thiosulfate utilization.


:

Pssm-ID: 468977  Cd Length: 72  Bit Score: 137.76  E-value: 9.68e-45
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 16129953   3 IKKLDVVTQVCPFPLIEAKAALAEMVSGDELVIEFDCTQATEAIPQWAAEEGHAITDYQQIGDAAWSITVQK 74
Cdd:NF041048  1 IKKLDVVTQVCPFPLIEAKAAMAELASGDELVIDFDCTQATEAIPQWAAEEGHSVTDYQQVGDAAWSITVQK 72
 
Name Accession Description Interval E-value
TusA_like_YeeD NF041048
thiosulfate utilization sulfurtransferase TsuB/YeeD; YeeD (TsuB) is a TusA family putative ...
 3-74 9.68e-45

thiosulfate utilization sulfurtransferase TsuB/YeeD; YeeD (TsuB) is a TusA family putative sulfurtransferase associated with thiosulfate utilization.


Pssm-ID: 468977  Cd Length: 72  Bit Score: 137.76  E-value: 9.68e-45
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 16129953   3 IKKLDVVTQVCPFPLIEAKAALAEMVSGDELVIEFDCTQATEAIPQWAAEEGHAITDYQQIGDAAWSITVQK 74
Cdd:NF041048  1 IKKLDVVTQVCPFPLIEAKAAMAELASGDELVIDFDCTQATEAIPQWAAEEGHSVTDYQQVGDAAWSITVQK 72
TusA COG0425
Sulfur carrier protein TusA (tRNA thiolation, molybdenum cofactor biosynthesis) [Translation, ...
 6-75 5.54e-19

Sulfur carrier protein TusA (tRNA thiolation, molybdenum cofactor biosynthesis) [Translation, ribosomal structure and biogenesis, Coenzyme transport and metabolism, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440194  Cd Length: 70  Bit Score: 72.54  E-value: 5.54e-19
                       10        20        30        40        50        60        70
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129953  6 LDVVTQVCPFPLIEAKAALAEMVSGDELVIEFDCTQATEAIPQWAAEEGHAITDYQQIGDaAWSITVQKA 75
Cdd:COG0425  1 LDARGLSCPLPVLKTKKALEELKPGEVLEVLADDPGAVEDIPAWCRETGHELLSVEEEGG-VYRILIRKG 69
SirA_YedF_YeeD cd00291
SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain. SirA (also known as UvrY, and ...
 5-74 7.24e-19

SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain. SirA (also known as UvrY, and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA. A variety of microorganisms have similar proteins, all of which contain a common CPxP sequence motif in the N-terminal region. YhhP is suggested to be important for normal cell division and growth in rich nutrient medium. Moreover, despite a low primary sequence similarity, the YccP structure closely resembles the non-homologous C-terminal RNA-binding domain of E. coli translation initiation factor IF3. The signature CPxP motif serves to stabilize the N-terminal helix as part of the N-capping box and might be important in mRNA-binding.


Pssm-ID: 238180  Cd Length: 69  Bit Score: 72.20  E-value: 7.24e-19
                       10        20        30        40        50        60        70
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129953  5 KLDVVTQVCPFPLIEAKAALAEMVSGDELVIEFDCTQATEAIPQWAAEEGHAITDYQQIGDaAWSITVQK 74
Cdd:cd00291  1 TLDLRGLPCPLPVLKTKKALEKLKSGEVLEVLLDDPGAVEDIPAWAKETGHEVLEVEEEGG-VYRILIRK 69
TusA pfam01206
Sulfurtransferase TusA; This family includes the TusA sulfurtransferases.
 5-65 1.08e-13

Sulfurtransferase TusA; This family includes the TusA sulfurtransferases.


Pssm-ID: 426125  Cd Length: 64  Bit Score: 59.12  E-value: 1.08e-13
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 16129953    5 KLDVVTQVCPFPLIEAKAALAEMVSGDELVIEFDCTQATEAIPQWAAEEGHAITDYQQIGD 65
Cdd:pfam01206  1 TLDLRGLACPMPLLKTKKALKKLKPGEVLEVLADDPGAVEDIPRWAKETGHEVLEVEEEDG 61
PRK11018 PRK11018
putative sulfurtransferase YedF;
6-64 4.04e-09

putative sulfurtransferase YedF;


Pssm-ID: 236822  Cd Length: 78  Bit Score: 47.73  E-value: 4.04e-09
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 16129953   6 LDVVTQVCPFPLIEAKAALAEMVSGDELVIEFDCTQATEAIPQWAAEEGHAITDYQQIG 64
Cdd:PRK11018 11 LDMVGEPCPYPAVATLEALPQLKKGEILEVVSDCPQSINNIPLDARNHGYTVLDIQQDG 69
 
Name Accession Description Interval E-value
TusA_like_YeeD NF041048
thiosulfate utilization sulfurtransferase TsuB/YeeD; YeeD (TsuB) is a TusA family putative ...
 3-74 9.68e-45

thiosulfate utilization sulfurtransferase TsuB/YeeD; YeeD (TsuB) is a TusA family putative sulfurtransferase associated with thiosulfate utilization.


Pssm-ID: 468977  Cd Length: 72  Bit Score: 137.76  E-value: 9.68e-45
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 16129953   3 IKKLDVVTQVCPFPLIEAKAALAEMVSGDELVIEFDCTQATEAIPQWAAEEGHAITDYQQIGDAAWSITVQK 74
Cdd:NF041048  1 IKKLDVVTQVCPFPLIEAKAAMAELASGDELVIDFDCTQATEAIPQWAAEEGHSVTDYQQVGDAAWSITVQK 72
TusA COG0425
Sulfur carrier protein TusA (tRNA thiolation, molybdenum cofactor biosynthesis) [Translation, ...
 6-75 5.54e-19

Sulfur carrier protein TusA (tRNA thiolation, molybdenum cofactor biosynthesis) [Translation, ribosomal structure and biogenesis, Coenzyme transport and metabolism, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440194  Cd Length: 70  Bit Score: 72.54  E-value: 5.54e-19
                       10        20        30        40        50        60        70
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129953  6 LDVVTQVCPFPLIEAKAALAEMVSGDELVIEFDCTQATEAIPQWAAEEGHAITDYQQIGDaAWSITVQKA 75
Cdd:COG0425  1 LDARGLSCPLPVLKTKKALEELKPGEVLEVLADDPGAVEDIPAWCRETGHELLSVEEEGG-VYRILIRKG 69
SirA_YedF_YeeD cd00291
SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain. SirA (also known as UvrY, and ...
 5-74 7.24e-19

SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain. SirA (also known as UvrY, and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA. A variety of microorganisms have similar proteins, all of which contain a common CPxP sequence motif in the N-terminal region. YhhP is suggested to be important for normal cell division and growth in rich nutrient medium. Moreover, despite a low primary sequence similarity, the YccP structure closely resembles the non-homologous C-terminal RNA-binding domain of E. coli translation initiation factor IF3. The signature CPxP motif serves to stabilize the N-terminal helix as part of the N-capping box and might be important in mRNA-binding.


Pssm-ID: 238180  Cd Length: 69  Bit Score: 72.20  E-value: 7.24e-19
                       10        20        30        40        50        60        70
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129953  5 KLDVVTQVCPFPLIEAKAALAEMVSGDELVIEFDCTQATEAIPQWAAEEGHAITDYQQIGDaAWSITVQK 74
Cdd:cd00291  1 TLDLRGLPCPLPVLKTKKALEKLKSGEVLEVLLDDPGAVEDIPAWAKETGHEVLEVEEEGG-VYRILIRK 69
TusA pfam01206
Sulfurtransferase TusA; This family includes the TusA sulfurtransferases.
 5-65 1.08e-13

Sulfurtransferase TusA; This family includes the TusA sulfurtransferases.


Pssm-ID: 426125  Cd Length: 64  Bit Score: 59.12  E-value: 1.08e-13
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 16129953    5 KLDVVTQVCPFPLIEAKAALAEMVSGDELVIEFDCTQATEAIPQWAAEEGHAITDYQQIGD 65
Cdd:pfam01206  1 TLDLRGLACPMPLLKTKKALKKLKPGEVLEVLADDPGAVEDIPRWAKETGHEVLEVEEEDG 61
PRK11018 PRK11018
putative sulfurtransferase YedF;
6-64 4.04e-09

putative sulfurtransferase YedF;


Pssm-ID: 236822  Cd Length: 78  Bit Score: 47.73  E-value: 4.04e-09
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 16129953   6 LDVVTQVCPFPLIEAKAALAEMVSGDELVIEFDCTQATEAIPQWAAEEGHAITDYQQIG 64
Cdd:PRK11018 11 LDMVGEPCPYPAVATLEALPQLKKGEILEVVSDCPQSINNIPLDARNHGYTVLDIQQDG 69
YedF cd03422
YedF is a bacterial SirA-like protein of unknown function. SirA (also known as UvrY, and ...
 5-64 1.53e-07

YedF is a bacterial SirA-like protein of unknown function. SirA (also known as UvrY, and YhhP) belongs to a family of a two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA. A variety of microorganisms have similar proteins, all of which contain a common CPxP sequence motif in the N-terminal region. YhhP is suggested to be important for normal cell division and growth in rich nutrient medium. Moreover, despite a low primary sequence similarity, the YccP structure closely resembles the non-homologous C-terminal RNA-binding domain of E. coli translation initiation factor IF3. The signature CPxP motif serves to stabilize the N-terminal helix as part of the N-capping box and might be important in mRNA-binding.


Pssm-ID: 239514  Cd Length: 69  Bit Score: 43.57  E-value: 1.53e-07
                       10        20        30        40        50        60
               ....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129953  5 KLDVVTQVCPFPLIEAKAALAEMVSGDELVIEFDCTQATEAIPQWAAEEGHAITDYQQIG 64
Cdd:cd03422  1 RLDLRGEPCPYPAIATLEALPSLKPGEILEVISDCPQSINNIPIDARNHGYKVLAIEQSG 60
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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