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Conserved domains on  [gi|16130262|ref|NP_416830|]
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putative transporter YfcA [Escherichia coli str. K-12 substr. MG1655]

Protein Classification

sulfite exporter TauE/SafE family protein( domain architecture ID 10013582)

sulfite exporter TauE/SafE family protein is an inner membrane anion permease involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate; similar to Escherichia coli probable membrane transporter protein YfcA

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK10621 PRK10621
hypothetical protein; Provisional
 4-269 2.56e-162

hypothetical protein; Provisional


:

Pssm-ID: 182593  Cd Length: 266  Bit Score: 450.69  E-value: 2.56e-162
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130262    4 FNSLFMVSPLLLGVLFFVAMLAGFIDSIAGGGGLLTIPALMAAGMSPANALATNKLQACGGSISATIYFIRRKVVSLSDQ 83
Cdd:PRK10621   1 FMDLFMVSPLLLGVLFFVAMLAGFIDSIAGGGGLLTIPALLAAGMSPAQALATNKLQACGGSFSASLYFIRRKVVNLADQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130262   84 KLNIAMTFVGSMSGALLVQYVQADVLRQILPILVICIGLYFLLMPKLGEEDRQRRMYGLPFALIAGGCVGFYDGFFGPAA 163
Cdd:PRK10621  81 KLNIAMTFVGSMSGALLVQYVQADILRQILPILVIGIGLYFLLMPKLGEEDRQRRLYGLPFALIAGGCVGFYDGFFGPGA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130262  164 GSFYALAFVTLCGFNLAKATAHAKLLNATSNIGGLLLFILGGKVIWATGFVMLVGQFLGARMGSRLVLSKGQKLIRPMIV 243
Cdd:PRK10621 161 GSFYALAFVTLCGFNLAKATAHAKVLNATSNIGGLLLFILGGKVIWATGFVMLVGQFLGARLGARLVLSKGQKLIRPMIV 240

                        250       260
                 ....*....|....*....|....*.
gi 16130262  244 IVSAVMSAKLLYDSHGQEILHWLGMN 269
Cdd:PRK10621 241 IVSAVMSAKLLYDSHGQEILHWLGMN 266
 
Name Accession Description Interval E-value
PRK10621 PRK10621
hypothetical protein; Provisional
 4-269 2.56e-162

hypothetical protein; Provisional


Pssm-ID: 182593  Cd Length: 266  Bit Score: 450.69  E-value: 2.56e-162
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130262    4 FNSLFMVSPLLLGVLFFVAMLAGFIDSIAGGGGLLTIPALMAAGMSPANALATNKLQACGGSISATIYFIRRKVVSLSDQ 83
Cdd:PRK10621   1 FMDLFMVSPLLLGVLFFVAMLAGFIDSIAGGGGLLTIPALLAAGMSPAQALATNKLQACGGSFSASLYFIRRKVVNLADQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130262   84 KLNIAMTFVGSMSGALLVQYVQADVLRQILPILVICIGLYFLLMPKLGEEDRQRRMYGLPFALIAGGCVGFYDGFFGPAA 163
Cdd:PRK10621  81 KLNIAMTFVGSMSGALLVQYVQADILRQILPILVIGIGLYFLLMPKLGEEDRQRRLYGLPFALIAGGCVGFYDGFFGPGA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130262  164 GSFYALAFVTLCGFNLAKATAHAKLLNATSNIGGLLLFILGGKVIWATGFVMLVGQFLGARMGSRLVLSKGQKLIRPMIV 243
Cdd:PRK10621 161 GSFYALAFVTLCGFNLAKATAHAKVLNATSNIGGLLLFILGGKVIWATGFVMLVGQFLGARLGARLVLSKGQKLIRPMIV 240

                        250       260
                 ....*....|....*....|....*.
gi 16130262  244 IVSAVMSAKLLYDSHGQEILHWLGMN 269
Cdd:PRK10621 241 IVSAVMSAKLLYDSHGQEILHWLGMN 266
TauE COG0730
Sulfite exporter TauE/SafE/YfcA and related permeases, UPF0721 family [Inorganic ion transport ...
 12-257 1.85e-45

Sulfite exporter TauE/SafE/YfcA and related permeases, UPF0721 family [Inorganic ion transport and metabolism];


Pssm-ID: 440494  Cd Length: 250  Bit Score: 153.04  E-value: 1.85e-45
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130262  12 PLLLGVLFFVAMLAGFIDSIAG-GGGLLTIPALMAAGMSPANALATNKLQACGGSISATIYFIRRKVVSLSDQKLNIAMT 90
Cdd:COG0730   1 LMLLLLLLLAGFLAGFLDGLLGvGGGLITVPALLLFGLPPAVAVGTSLLAVVFTSLSGALAHRRRGNVDWRLLLPLALGA 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130262  91 FVGSMSGALLVQYVQADVLRQILPILVICIGLYFLLMPKLGEEDRQRRMY-GLPFALIAGGCVGFYDGFFGPAAGSFYAL 169
Cdd:COG0730  81 LIGALLGALLLLLLPADVLKLLFGVLLLLVALLMLLRPKPGAEPERRLPRrSPLLLLLLGFVIGFLSGLFGIGGGFLLVP 160

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130262 170 AFVTLCGFNLAKATAHAKLLNATSNIGGLLLFILGGKVIWATGFVMLVGQFLGARMGSRLVLSKGQKLIRPMIVIVSAVM 249
Cdd:COG0730 161 ALVLLLGLPLKRAVATSLALIFVTALAGLIGFALLGYVDWPLALLLALGSLLGAYLGARLARRLPPKLLRRLFAVVLLLV 240


                ....*...
gi 16130262 250 SAKLLYDS 257
Cdd:COG0730 241 GLKLLLKA 248
TauE pfam01925
Sulfite exporter TauE/SafE; This is a family of integral membrane proteins where the alignment ...
 19-252 5.63e-30

Sulfite exporter TauE/SafE; This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.


Pssm-ID: 460386  Cd Length: 235  Bit Score: 112.29  E-value: 5.63e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130262    19 FFVAMLAGFIDSIAG-GGGLLTIPALMAaGMSPANALATNKLQACGGSISATIYFIRRKVVSLSDQKLNIAMTFVGSMSG 97
Cdd:pfam01925   1 LLAGLLAGFVGGLLGfGGGLIAVPLLLL-LLPPAVAVGTSLLAAVATSLSGALAHRRRGAVDWRLLLRLLLGGLIGALLG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130262    98 ALLVQYVQADVLRQILPILVICIGLYFLLMPKLG-EEDRQRRMYGLPFALIAGGCVGFYDGFFGPAAGSFYALAFVTLCG 176
Cdd:pfam01925  80 ALLLLLLPEALLKLLFGVLLLLAALLMLLRRRLGaAPRARRRRPGPLALALLGGLIGFLSGLFGIGGGFLLVPALLYLLG 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 16130262   177 FNLAKATAHAKLLNATSNIGGLLLFILGGKVIWATGFVMLVGQFLGARMGSRLVLSKGQKLIRPMIVIVSAVMSAK 252
Cdd:pfam01925 160 LPLKKAVGTSLLLFLVSNLAALLGYALLGAVDWPLLLLLLLGALLGAYLGARLARRLPPRLLRRLFAVLLLLVGLK 235
 
Name Accession Description Interval E-value
PRK10621 PRK10621
hypothetical protein; Provisional
 4-269 2.56e-162

hypothetical protein; Provisional


Pssm-ID: 182593  Cd Length: 266  Bit Score: 450.69  E-value: 2.56e-162
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130262    4 FNSLFMVSPLLLGVLFFVAMLAGFIDSIAGGGGLLTIPALMAAGMSPANALATNKLQACGGSISATIYFIRRKVVSLSDQ 83
Cdd:PRK10621   1 FMDLFMVSPLLLGVLFFVAMLAGFIDSIAGGGGLLTIPALLAAGMSPAQALATNKLQACGGSFSASLYFIRRKVVNLADQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130262   84 KLNIAMTFVGSMSGALLVQYVQADVLRQILPILVICIGLYFLLMPKLGEEDRQRRMYGLPFALIAGGCVGFYDGFFGPAA 163
Cdd:PRK10621  81 KLNIAMTFVGSMSGALLVQYVQADILRQILPILVIGIGLYFLLMPKLGEEDRQRRLYGLPFALIAGGCVGFYDGFFGPGA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130262  164 GSFYALAFVTLCGFNLAKATAHAKLLNATSNIGGLLLFILGGKVIWATGFVMLVGQFLGARMGSRLVLSKGQKLIRPMIV 243
Cdd:PRK10621 161 GSFYALAFVTLCGFNLAKATAHAKVLNATSNIGGLLLFILGGKVIWATGFVMLVGQFLGARLGARLVLSKGQKLIRPMIV 240

                        250       260
                 ....*....|....*....|....*.
gi 16130262  244 IVSAVMSAKLLYDSHGQEILHWLGMN 269
Cdd:PRK10621 241 IVSAVMSAKLLYDSHGQEILHWLGMN 266
TauE COG0730
Sulfite exporter TauE/SafE/YfcA and related permeases, UPF0721 family [Inorganic ion transport ...
 12-257 1.85e-45

Sulfite exporter TauE/SafE/YfcA and related permeases, UPF0721 family [Inorganic ion transport and metabolism];


Pssm-ID: 440494  Cd Length: 250  Bit Score: 153.04  E-value: 1.85e-45
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130262  12 PLLLGVLFFVAMLAGFIDSIAG-GGGLLTIPALMAAGMSPANALATNKLQACGGSISATIYFIRRKVVSLSDQKLNIAMT 90
Cdd:COG0730   1 LMLLLLLLLAGFLAGFLDGLLGvGGGLITVPALLLFGLPPAVAVGTSLLAVVFTSLSGALAHRRRGNVDWRLLLPLALGA 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130262  91 FVGSMSGALLVQYVQADVLRQILPILVICIGLYFLLMPKLGEEDRQRRMY-GLPFALIAGGCVGFYDGFFGPAAGSFYAL 169
Cdd:COG0730  81 LIGALLGALLLLLLPADVLKLLFGVLLLLVALLMLLRPKPGAEPERRLPRrSPLLLLLLGFVIGFLSGLFGIGGGFLLVP 160

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130262 170 AFVTLCGFNLAKATAHAKLLNATSNIGGLLLFILGGKVIWATGFVMLVGQFLGARMGSRLVLSKGQKLIRPMIVIVSAVM 249
Cdd:COG0730 161 ALVLLLGLPLKRAVATSLALIFVTALAGLIGFALLGYVDWPLALLLALGSLLGAYLGARLARRLPPKLLRRLFAVVLLLV 240


                ....*...
gi 16130262 250 SAKLLYDS 257
Cdd:COG0730 241 GLKLLLKA 248
TauE pfam01925
Sulfite exporter TauE/SafE; This is a family of integral membrane proteins where the alignment ...
 19-252 5.63e-30

Sulfite exporter TauE/SafE; This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.


Pssm-ID: 460386  Cd Length: 235  Bit Score: 112.29  E-value: 5.63e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130262    19 FFVAMLAGFIDSIAG-GGGLLTIPALMAaGMSPANALATNKLQACGGSISATIYFIRRKVVSLSDQKLNIAMTFVGSMSG 97
Cdd:pfam01925   1 LLAGLLAGFVGGLLGfGGGLIAVPLLLL-LLPPAVAVGTSLLAAVATSLSGALAHRRRGAVDWRLLLRLLLGGLIGALLG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130262    98 ALLVQYVQADVLRQILPILVICIGLYFLLMPKLG-EEDRQRRMYGLPFALIAGGCVGFYDGFFGPAAGSFYALAFVTLCG 176
Cdd:pfam01925  80 ALLLLLLPEALLKLLFGVLLLLAALLMLLRRRLGaAPRARRRRPGPLALALLGGLIGFLSGLFGIGGGFLLVPALLYLLG 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 16130262   177 FNLAKATAHAKLLNATSNIGGLLLFILGGKVIWATGFVMLVGQFLGARMGSRLVLSKGQKLIRPMIVIVSAVMSAK 252
Cdd:pfam01925 160 LPLKKAVGTSLLLFLVSNLAALLGYALLGAVDWPLLLLLLLGALLGAYLGARLARRLPPRLLRRLFAVLLLLVGLK 235
TauE pfam01925
Sulfite exporter TauE/SafE; This is a family of integral membrane proteins where the alignment ...
 17-123 1.20e-03

Sulfite exporter TauE/SafE; This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.


Pssm-ID: 460386  Cd Length: 235  Bit Score: 39.10  E-value: 1.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130262    17 VLFFVAMLAGFIDSIAG-GGGLLTIPALMAA-GMSPANALATNKLQACGGSISATIYFIRRKVVSLSDQKLNIAMTFVGS 94
Cdd:pfam01925 127 ALALLGGLIGFLSGLFGiGGGFLLVPALLYLlGLPLKKAVGTSLLLFLVSNLAALLGYALLGAVDWPLLLLLLLGALLGA 206

                          90       100
                  ....*....|....*....|....*....
gi 16130262    95 MSGALLVQYVQADVLRQILPILVICIGLY 123
Cdd:pfam01925 207 YLGARLARRLPPRLLRRLFAVLLLLVGLK 235
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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