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Conserved domains on  [gi|16130377|ref|NP_416947|]
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putative ethanolamine permease EutH [Escherichia coli str. K-12 substr. MG1655]

Protein Classification

ethanolamine utilization protein EutH( domain architecture ID 10014976)

ethanolamine utilization protein EutH may be involved in the transport of ethanolamine

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
PRK15086 PRK15086
ethanolamine utilization protein EutH; Provisional
1-408 4.06e-161

ethanolamine utilization protein EutH; Provisional


:

Pssm-ID: 237906  Cd Length: 372  Bit Score: 457.80  E-value: 4.06e-161
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130377    1 MGINEIIMYIMMFFMLIAAVDRIlsqfggsarflgkFGKSIEGSGGQFEEGFMAMGALGLAMVGMTALAPVLAHVLGPVI 80
Cdd:PRK15086   1 MGINEIIIYIMMFFMLIGAIDRI-------------IGNKFEGLGEQFEEGIMAMGPLALAMVGIMALAPVLAHVLGPVI 67
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130377   81 IPVYEMLGANPSMFAGTLLACDMGGFFLAKELAGgDVAAWLYSGLILGSMMGPTIVFSIPVALGIIEPSDRRYLALGVLA 160
Cdd:PRK15086  68 IPIYEALGADPSMFATTLLAVDMGGYQLAKELAG-DPEAWLFSGLILGSMMGATIVFTIPVALGIIEKEDRKYLALGVLA 146
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130377  161 GIVTIPIGCIAGGLVAmysgvqingqpvEFTFALILMNMIPVIIVAILVALGLKFIPEKMINGFQIFAKFLVALITLGLA 240
Cdd:PRK15086 147 GIITIPIGCLIGGLVA------------GFDFALILRNLIPVIIFAILLALGLKFIPEKMIKGFLIFGKFIVALITIGLA 214
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130377  241 AAVVKFLLGWELIPGLDPIFMapgdkpgevmRAIEVIGSISCVLLGAYPMVLLLTRWFEKPLMSVGKVLNMNNIAAAGMV 320
Cdd:PRK15086 215 AAIVQSLTGWKLIPGFDPIKF----------EAIEIVGSIAIVLAGAFPMVYLITKVFKKPLMKVGKLLGMNEVAAAGMV 284
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130377  321 ATLANNIPMFGMMKQMDTRGKVINCAFAVSAAFALGDHLGFAAANMNAMIFPMIVGKLIGGVTAIGVAMMLVPKEDATAT 400
Cdd:PRK15086 285 ATLANNIPMFGMMKDMDPRGKVINVAFAVSAAFVLGDHLGFTAGVQPTMIFPMIVGKLIGGITAIGVAILLSVKKAAALE 364

                 ....*...
gi 16130377  401 KTEAEAQS 408
Cdd:PRK15086 365 KTEAEAQS 372
 
Name Accession Description Interval E-value
PRK15086 PRK15086
ethanolamine utilization protein EutH; Provisional
1-408 4.06e-161

ethanolamine utilization protein EutH; Provisional


Pssm-ID: 237906  Cd Length: 372  Bit Score: 457.80  E-value: 4.06e-161
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130377    1 MGINEIIMYIMMFFMLIAAVDRIlsqfggsarflgkFGKSIEGSGGQFEEGFMAMGALGLAMVGMTALAPVLAHVLGPVI 80
Cdd:PRK15086   1 MGINEIIIYIMMFFMLIGAIDRI-------------IGNKFEGLGEQFEEGIMAMGPLALAMVGIMALAPVLAHVLGPVI 67
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130377   81 IPVYEMLGANPSMFAGTLLACDMGGFFLAKELAGgDVAAWLYSGLILGSMMGPTIVFSIPVALGIIEPSDRRYLALGVLA 160
Cdd:PRK15086  68 IPIYEALGADPSMFATTLLAVDMGGYQLAKELAG-DPEAWLFSGLILGSMMGATIVFTIPVALGIIEKEDRKYLALGVLA 146
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130377  161 GIVTIPIGCIAGGLVAmysgvqingqpvEFTFALILMNMIPVIIVAILVALGLKFIPEKMINGFQIFAKFLVALITLGLA 240
Cdd:PRK15086 147 GIITIPIGCLIGGLVA------------GFDFALILRNLIPVIIFAILLALGLKFIPEKMIKGFLIFGKFIVALITIGLA 214
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130377  241 AAVVKFLLGWELIPGLDPIFMapgdkpgevmRAIEVIGSISCVLLGAYPMVLLLTRWFEKPLMSVGKVLNMNNIAAAGMV 320
Cdd:PRK15086 215 AAIVQSLTGWKLIPGFDPIKF----------EAIEIVGSIAIVLAGAFPMVYLITKVFKKPLMKVGKLLGMNEVAAAGMV 284
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130377  321 ATLANNIPMFGMMKQMDTRGKVINCAFAVSAAFALGDHLGFAAANMNAMIFPMIVGKLIGGVTAIGVAMMLVPKEDATAT 400
Cdd:PRK15086 285 ATLANNIPMFGMMKDMDPRGKVINVAFAVSAAFVLGDHLGFTAGVQPTMIFPMIVGKLIGGITAIGVAILLSVKKAAALE 364

                 ....*...
gi 16130377  401 KTEAEAQS 408
Cdd:PRK15086 365 KTEAEAQS 372
EutH COG3192
Ethanolamine transporter EutH, required for ethanolamine utilization at low pH [Amino acid ...
1-405 4.16e-161

Ethanolamine transporter EutH, required for ethanolamine utilization at low pH [Amino acid transport and metabolism];


Pssm-ID: 442425  Cd Length: 367  Bit Score: 457.38  E-value: 4.16e-161
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130377   1 MGINEIIMYIMMFFMLIAAVDRILSQfggsarflgKFGksiegSGGQFEEGFMAMGALGLAMVGMTALAPVLAHVLGPVI 80
Cdd:COG3192   1 MSINEIIIYIMMIFMVLGAIDKILGN---------KFG-----LGEEFEEGFMAMGPLALAMVGIIALAPVLAEFLSPVI 66
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130377  81 IPVYEMLGANPSMFAGTLLACDMGGFFLAKELAGgDVAAWLYSGLILGSMMGPTIVFSIPVALGIIEPSDRRYLALGVLA 160
Cdd:COG3192  67 GPLYTALGADPSMFATTILANDMGGYPLAEELAQ-DPEAGLFAGLILGSMMGATIVFTIPVALGIIEKEDHKYLALGVLI 145
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130377 161 GIVTIPIGCIAGGLVAMysgvqingqpveFTFALILMNMIPVIIVAILVALGLKFIPEKMINGFQIFAKFLVALITLGLA 240
Cdd:COG3192 146 GIITIPIGCLAGGLVAG------------FDIGMVLRNLIPVIIFAVLIALGLWFAPDKMIKGFLVFGKFMVAVITIGLA 213
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130377 241 AAVVKFLLGWELIPGLDPIFmapgdkpgevmRAIEVIGSISCVLLGAYPMVLLLTRWFEKPLMSVGKVLNMNNIAAAGMV 320
Cdd:COG3192 214 AAIVEYLTGIPIIPGMAPLF-----------EAIEIVGKIAIVLAGAFPLVYLITKVFKKPLEKLGKKLGINEVGAAGLL 282
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130377 321 ATLANNIPMFGMMKQMDTRGKVINCAFAVSAAFALGDHLGFAAANMNAMIFPMIVGKLIGGVTAIGVAMMLVPKEDATAT 400
Cdd:COG3192 283 ATLANNIPMFGMMKDMDPRGKVINVAFAVSAAFVFGDHLGFTAGFQPDMIFPMIVGKLVGGILAIIVALLLTRKEAKKLE 362

                ....*
gi 16130377 401 KTEAE 405
Cdd:COG3192 363 KKDAA 367
EutH pfam04346
Ethanolamine utilization protein, EutH; EutH is a bacterial membrane protein whose molecular ...
3-391 2.52e-144

Ethanolamine utilization protein, EutH; EutH is a bacterial membrane protein whose molecular function is unknown. It has been suggested that it may act as an ethanolamine transporter, responsible for carrying ethanolamine from the periplasm to the cytoplasm.


Pssm-ID: 427882  Cd Length: 351  Bit Score: 414.22  E-value: 2.52e-144
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130377     3 INEIIMYIMMFFMLIAAVDRILSqfggsarflGKFGksiegSGGQFEEGFMAMGALGLAMVGMTALAPVLAHVLGPVIIP 82
Cdd:pfam04346   1 INEIIIYIMAIFAVIGAIDRILG---------NKFG-----LGEEFEEGFMAMGPLALSMVGIICLAPVLAKILAPIIVP 66
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130377    83 VYEMLGANPSMFAGTLLACDMGGFFLAKELAGgDVAAWLYSGLILGSMMGPTIVFSIPVALGIIEPSDRRYLALGVLAGI 162
Cdd:pfam04346  67 LYSALGADPSMFAGTILAIDMGGYQLAMELAA-DPEAGLFSGLILGSMLGATIVFTIPVALGMIEKEDHKYLAKGILAGI 145
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130377   163 VTIPIGCIAGGLVAmysgvqingqpvEFTFALILMNMIPVIIVAILVALGLKFIPEKMINGFQIFAKFLVALITLGLAAA 242
Cdd:pfam04346 146 ITIPIGCLVGGLVA------------GFPIGMLLRNLLPVIIFAVLLALGLWFFPEKMIKGFLVFGKGIVALITIGLAAA 213
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130377   243 VVKFLLGWELIPGLDPIFmapgdkpgevmRAIEVIGSISCVLLGAYPMVLLLTRWFEKPLMSVGKVLNMNNIAAAGMVAT 322
Cdd:pfam04346 214 IVEYLTGIVLIPGMAPIS-----------EALEIVGSIAIVLAGAFPLVYLITKVFKKPLEKLGRKLGINEVAAAGLLAS 282
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 16130377   323 LANNIPMFGMMKQMDTRGKVINCAFAVSAAFALGDHLGFAAANMNAMIFPMIVGKLIGGVTAIGVAMML 391
Cdd:pfam04346 283 LANSIPMFALMKDMDERGKVINIAFAVSAAFVFGDHLGFTAGVEPDMILPMIVGKLVGGILAVALALLL 351
 
Name Accession Description Interval E-value
PRK15086 PRK15086
ethanolamine utilization protein EutH; Provisional
1-408 4.06e-161

ethanolamine utilization protein EutH; Provisional


Pssm-ID: 237906  Cd Length: 372  Bit Score: 457.80  E-value: 4.06e-161
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130377    1 MGINEIIMYIMMFFMLIAAVDRIlsqfggsarflgkFGKSIEGSGGQFEEGFMAMGALGLAMVGMTALAPVLAHVLGPVI 80
Cdd:PRK15086   1 MGINEIIIYIMMFFMLIGAIDRI-------------IGNKFEGLGEQFEEGIMAMGPLALAMVGIMALAPVLAHVLGPVI 67
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130377   81 IPVYEMLGANPSMFAGTLLACDMGGFFLAKELAGgDVAAWLYSGLILGSMMGPTIVFSIPVALGIIEPSDRRYLALGVLA 160
Cdd:PRK15086  68 IPIYEALGADPSMFATTLLAVDMGGYQLAKELAG-DPEAWLFSGLILGSMMGATIVFTIPVALGIIEKEDRKYLALGVLA 146
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130377  161 GIVTIPIGCIAGGLVAmysgvqingqpvEFTFALILMNMIPVIIVAILVALGLKFIPEKMINGFQIFAKFLVALITLGLA 240
Cdd:PRK15086 147 GIITIPIGCLIGGLVA------------GFDFALILRNLIPVIIFAILLALGLKFIPEKMIKGFLIFGKFIVALITIGLA 214
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130377  241 AAVVKFLLGWELIPGLDPIFMapgdkpgevmRAIEVIGSISCVLLGAYPMVLLLTRWFEKPLMSVGKVLNMNNIAAAGMV 320
Cdd:PRK15086 215 AAIVQSLTGWKLIPGFDPIKF----------EAIEIVGSIAIVLAGAFPMVYLITKVFKKPLMKVGKLLGMNEVAAAGMV 284
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130377  321 ATLANNIPMFGMMKQMDTRGKVINCAFAVSAAFALGDHLGFAAANMNAMIFPMIVGKLIGGVTAIGVAMMLVPKEDATAT 400
Cdd:PRK15086 285 ATLANNIPMFGMMKDMDPRGKVINVAFAVSAAFVLGDHLGFTAGVQPTMIFPMIVGKLIGGITAIGVAILLSVKKAAALE 364

                 ....*...
gi 16130377  401 KTEAEAQS 408
Cdd:PRK15086 365 KTEAEAQS 372
EutH COG3192
Ethanolamine transporter EutH, required for ethanolamine utilization at low pH [Amino acid ...
1-405 4.16e-161

Ethanolamine transporter EutH, required for ethanolamine utilization at low pH [Amino acid transport and metabolism];


Pssm-ID: 442425  Cd Length: 367  Bit Score: 457.38  E-value: 4.16e-161
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130377   1 MGINEIIMYIMMFFMLIAAVDRILSQfggsarflgKFGksiegSGGQFEEGFMAMGALGLAMVGMTALAPVLAHVLGPVI 80
Cdd:COG3192   1 MSINEIIIYIMMIFMVLGAIDKILGN---------KFG-----LGEEFEEGFMAMGPLALAMVGIIALAPVLAEFLSPVI 66
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130377  81 IPVYEMLGANPSMFAGTLLACDMGGFFLAKELAGgDVAAWLYSGLILGSMMGPTIVFSIPVALGIIEPSDRRYLALGVLA 160
Cdd:COG3192  67 GPLYTALGADPSMFATTILANDMGGYPLAEELAQ-DPEAGLFAGLILGSMMGATIVFTIPVALGIIEKEDHKYLALGVLI 145
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130377 161 GIVTIPIGCIAGGLVAMysgvqingqpveFTFALILMNMIPVIIVAILVALGLKFIPEKMINGFQIFAKFLVALITLGLA 240
Cdd:COG3192 146 GIITIPIGCLAGGLVAG------------FDIGMVLRNLIPVIIFAVLIALGLWFAPDKMIKGFLVFGKFMVAVITIGLA 213
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130377 241 AAVVKFLLGWELIPGLDPIFmapgdkpgevmRAIEVIGSISCVLLGAYPMVLLLTRWFEKPLMSVGKVLNMNNIAAAGMV 320
Cdd:COG3192 214 AAIVEYLTGIPIIPGMAPLF-----------EAIEIVGKIAIVLAGAFPLVYLITKVFKKPLEKLGKKLGINEVGAAGLL 282
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130377 321 ATLANNIPMFGMMKQMDTRGKVINCAFAVSAAFALGDHLGFAAANMNAMIFPMIVGKLIGGVTAIGVAMMLVPKEDATAT 400
Cdd:COG3192 283 ATLANNIPMFGMMKDMDPRGKVINVAFAVSAAFVFGDHLGFTAGFQPDMIFPMIVGKLVGGILAIIVALLLTRKEAKKLE 362

                ....*
gi 16130377 401 KTEAE 405
Cdd:COG3192 363 KKDAA 367
EutH pfam04346
Ethanolamine utilization protein, EutH; EutH is a bacterial membrane protein whose molecular ...
3-391 2.52e-144

Ethanolamine utilization protein, EutH; EutH is a bacterial membrane protein whose molecular function is unknown. It has been suggested that it may act as an ethanolamine transporter, responsible for carrying ethanolamine from the periplasm to the cytoplasm.


Pssm-ID: 427882  Cd Length: 351  Bit Score: 414.22  E-value: 2.52e-144
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130377     3 INEIIMYIMMFFMLIAAVDRILSqfggsarflGKFGksiegSGGQFEEGFMAMGALGLAMVGMTALAPVLAHVLGPVIIP 82
Cdd:pfam04346   1 INEIIIYIMAIFAVIGAIDRILG---------NKFG-----LGEEFEEGFMAMGPLALSMVGIICLAPVLAKILAPIIVP 66
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130377    83 VYEMLGANPSMFAGTLLACDMGGFFLAKELAGgDVAAWLYSGLILGSMMGPTIVFSIPVALGIIEPSDRRYLALGVLAGI 162
Cdd:pfam04346  67 LYSALGADPSMFAGTILAIDMGGYQLAMELAA-DPEAGLFSGLILGSMLGATIVFTIPVALGMIEKEDHKYLAKGILAGI 145
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130377   163 VTIPIGCIAGGLVAmysgvqingqpvEFTFALILMNMIPVIIVAILVALGLKFIPEKMINGFQIFAKFLVALITLGLAAA 242
Cdd:pfam04346 146 ITIPIGCLVGGLVA------------GFPIGMLLRNLLPVIIFAVLLALGLWFFPEKMIKGFLVFGKGIVALITIGLAAA 213
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130377   243 VVKFLLGWELIPGLDPIFmapgdkpgevmRAIEVIGSISCVLLGAYPMVLLLTRWFEKPLMSVGKVLNMNNIAAAGMVAT 322
Cdd:pfam04346 214 IVEYLTGIVLIPGMAPIS-----------EALEIVGSIAIVLAGAFPLVYLITKVFKKPLEKLGRKLGINEVAAAGLLAS 282
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 16130377   323 LANNIPMFGMMKQMDTRGKVINCAFAVSAAFALGDHLGFAAANMNAMIFPMIVGKLIGGVTAIGVAMML 391
Cdd:pfam04346 283 LANSIPMFALMKDMDERGKVINIAFAVSAAFVFGDHLGFTAGVEPDMILPMIVGKLVGGILAVALALLL 351
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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