|
Name |
Accession |
Description |
Interval |
E-value |
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
145-469 |
5.38e-59 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 197.05 E-value: 5.38e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 145 ANTEMVQATRTVVFSRGQQLQREIAERGQYFGWQSLVLFLVSLVMVLLFTRMIIGPVKNIERMINRLGEGRSLGNSVSFS 224
Cdd:COG0642 5 LLLLVLLLLLLLLLLLALLLLLLLLLLLALLLLLALLLLLLLLLLLLLLLALALLALLLLLLLLLLLLLLLLLLLLLLLL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 225 GPSELRSVGQRILWLSERLSWLESQRHQFLRHLSHELKTPLASMREGTELLADQVvgplTPEQKEVVSILDSSSRNLQKL 304
Cdd:COG0642 85 LLLLLLLLLLLLLALLLLLEEANEAKSRFLANVSHELRTPLTAIRGYLELLLEEL----DEEQREYLETILRSADRLLRL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 305 IEQLLDYNRKQADS-AVELENVELAPLVETVVSAHSLPARAKMMHTDVDLKATAC--LAEPMLLMSVLDNLYSNAVHYGA 381
Cdd:COG0642 161 INDLLDLSRLEAGKlELEPEPVDLAELLEEVVELFRPLAEEKGIELELDLPDDLPtvRGDPDRLRQVLLNLLSNAIKYTP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 382 ESGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFQGSHQRKGavKGSGLGLSIARDCIRRMQGELYLVDESGQD 461
Cdd:COG0642 241 EGGTVTVSVRREGDRVRISVEDTGPGIPPEDLERIFEPFFRTDPSRRG--GGTGLGLAIVKRIVELHGGTIEVESEPGKG 318
|
....*...
gi 90111458 462 VCFRIELP 469
Cdd:COG0642 319 TTFTVTLP 326
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
246-469 |
3.62e-57 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 189.35 E-value: 3.62e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 246 LESQRHQFLRHLSHELKTPLASMREGTELLADQVvGPLTPEQKEVVSILDSSSRNLQKLIEQLLDYNRKQADS-AVELEN 324
Cdd:COG2205 12 LERLKSEFLANVSHELRTPLTSILGAAELLLDEE-DLSPEERRELLEIIRESAERLLRLIEDLLDLSRLESGKlSLELEP 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 325 VELAPLVETVVSAHSLPARAKMMHTDVDLKATACLAE--PMLLMSVLDNLYSNAVHYGAESGNICLRSSLHGARVYIDVI 402
Cdd:COG2205 91 VDLAELLEEAVEELRPLAEEKGIRLELDLPPELPLVYadPELLEQVLANLLDNAIKYSPPGGTITISARREGDGVRISVS 170
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 90111458 403 NTGTPIPQEERAMIFEPFFQGSHQRKgaVKGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIELP 469
Cdd:COG2205 171 DNGPGIPEEELERIFERFYRGDNSRG--EGGTGLGLAIVKRIVEAHGGTIWVESEPGGGTTFTVTLP 235
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
144-473 |
6.18e-55 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 188.22 E-value: 6.18e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 144 SANTEMVQATRTVVFSRGQQLQREIAERGQYFGWQSLVLFLVSLVMVLLFTRMIIGPVKNIERMINRLGEGRSLGNSVSF 223
Cdd:COG5002 63 LLLLALLLLLLLLLLLLALALLLLALLLLLLLLLLLLALLILLLLLALLILLAALLLLLSELLLLLLLLGRLSLRLSALL 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 224 SGPSELRSVGQRIlwlsERLSWLESQRHQFLRHLSHELKTPLASMREGTELLADQVVGPlTPEQKEVVSILDSSSRNLQK 303
Cdd:COG5002 143 LGLLLLAAVERDI----TELERLEQMRREFVANVSHELRTPLTSIRGYLELLLDGAADD-PEERREYLEIILEEAERLSR 217
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 304 LIEQLLDYNRKQADSA-VELENVELAPLVETVVSAHSLPARAKMMHTDVDLKATACL--AEPMLLMSVLDNLYSNAVHYG 380
Cdd:COG5002 218 LVNDLLDLSRLESGELkLEKEPVDLAELLEEVVEELRPLAEEKGIELELDLPEDPLLvlGDPDRLEQVLTNLLDNAIKYT 297
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 381 AESGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFQGSHQRKGAVKGSGLGLSIARDCIRRMQGELYLVDESGQ 460
Cdd:COG5002 298 PEGGTITVSLREEDDQVRISVRDTGIGIPEEDLPRIFERFYRVDKSRSRETGGTGLGLAIVKHIVEAHGGRIWVESEPGK 377
|
330
....*....|...
gi 90111458 461 DVCFRIELPSSKN 473
Cdd:COG5002 378 GTTFTITLPLARE 390
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
156-469 |
3.28e-34 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 131.84 E-value: 3.28e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 156 VVFSRGQQLQREIAERGQYFGWQSLVLFLVSLVMVLLFTRMIIGPVKNIERMINRLGEGRSLGNSVSFSGPSELRSVGQR 235
Cdd:COG4191 36 LLLLLALLLALLALLLLLLLLLLLLLLELLLLLLALLGGLLRLLLLLGLLLLLLLEALLLLLLAALDAEENAELEELERD 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 236 ILWLSERLSWLESQRHQfLRH-------------LSHELKTPLASMREGTELLADQVVGPLTPEQ-KEVVSILDSSSRNL 301
Cdd:COG4191 116 ITELERAEEELRELQEQ-LVQseklaalgelaagIAHEINNPLAAILGNAELLRRRLEDEPDPEElREALERILEGAERA 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 302 QKLIEQLLDYNRKQADsavELENVELAPLVETVVS--AHSLPARAKMMHTDVDLKATACLAEPMLLMSVLDNLYSNAVH- 378
Cdd:COG4191 195 AEIVRSLRAFSRRDEE---EREPVDLNELIDEALEllRPRLKARGIEVELDLPPDLPPVLGDPGQLEQVLLNLLINAIDa 271
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 379 -YGAESGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFQgshqRKGAVKGSGLGLSIARDCIRRMQGELYLVDE 457
Cdd:COG4191 272 mEEGEGGRITISTRREGDYVVISVRDNGPGIPPEVLERIFEPFFT----TKPVGKGTGLGLSISYGIVEKHGGRIEVESE 347
|
330
....*....|..
gi 90111458 458 SGQDVCFRIELP 469
Cdd:COG4191 348 PGGGTTFTITLP 359
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
175-469 |
7.92e-34 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 132.66 E-value: 7.92e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 175 FGWQSLVLFLVSLVMVLLFTRMIIGPVKNIERMINRLGEGRSLgnSVSFSGPSELRSVGQRilwlserlswLESQRHQ-- 252
Cdd:PRK11100 184 ILWAGALLLGIALLIGAGVVWWLNRSIRRLTRYADAVTEGKPV--PLPKLGSSELRELAQA----------LESMRVKle 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 253 -------FLRHLSHELKTPLASMREGTELLADqvvgPLTPEQKE--VVSILDSSSRnLQKLIEQLLDY----NRKQADsa 319
Cdd:PRK11100 252 gkayveqYVQTLTHELKSPLAAIRGAAELLQE----DPPPEDRArfTGNILTQSAR-LQQLIDRLLELarleQRQELE-- 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 320 vELENVELAPLVETVVSAHSLPARAKMMHTDVDLKATACLAEPMLLMSVLDNLYSNAVHYGAESGNICLRSSLHGARVYI 399
Cdd:PRK11100 325 -VLEPVALAALLEELVEAREAQAAAKGITLRLRPDDARVLGDPFLLRQALGNLLDNAIDFSPEGGTITLSAEVDGEQVAL 403
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 90111458 400 DVINTGTPIPQEERAMIFEPFFqgSHQRK-GAVKGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIELP 469
Cdd:PRK11100 404 SVEDQGPGIPDYALPRIFERFY--SLPRPaNGRKSTGLGLAFVREVARLHGGEVTLRNRPEGGVLATLTLP 472
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
228-469 |
1.20e-29 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 118.80 E-value: 1.20e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 228 ELRSVGQRiLWLSERLswLESQRHQFLRHLS----HELKTPLASMREGTELLADQVVGPltpEQKEVVSILDSSSRNLQK 303
Cdd:COG3852 112 VLRDITER-KRLEREL--RRAEKLAAVGELAaglaHEIRNPLTGIRGAAQLLERELPDD---ELREYTQLIIEEADRLNN 185
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 304 LIEQLLDYNRKQAdsaVELENVELAPLVETVVS-AHSLPARAKMMHTDVDLKATACLAEPMLLMSVLDNLYSNAVHYGAE 382
Cdd:COG3852 186 LVDRLLSFSRPRP---PEREPVNLHEVLERVLElLRAEAPKNIRIVRDYDPSLPEVLGDPDQLIQVLLNLVRNAAEAMPE 262
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 383 SGNICLRSSL----------HGARVYIDVINTGTPIPQEERAMIFEPFFQGshqrKGavKGSGLGLSIARDCIRRMQGEL 452
Cdd:COG3852 263 GGTITIRTRVerqvtlgglrPRLYVRIEVIDNGPGIPEEILDRIFEPFFTT----KE--KGTGLGLAIVQKIVEQHGGTI 336
|
250
....*....|....*..
gi 90111458 453 YLVDESGQDVCFRIELP 469
Cdd:COG3852 337 EVESEPGKGTTFRIYLP 353
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
246-469 |
1.62e-29 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 119.68 E-value: 1.62e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 246 LESQR----HQFLRHLSHELKTPLASMREGTELLADQVVGPLTPEQ---KEVVSILDSSSRNLQKLIEQLLDYNRKqadS 318
Cdd:COG5000 193 LRAERlaawGELARRIAHEIKNPLTPIQLSAERLRRKLADKLEEDRedlERALDTIIRQVDRLKRIVDEFLDFARL---P 269
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 319 AVELENVELAPLVETVVSAHSLPARAKMMHTDVDLKATACLAE--PMLLMSVLDNLYSNAVHYGAESGNICLRSSLHGAR 396
Cdd:COG5000 270 EPQLEPVDLNELLREVLALYEPALKEKDIRLELDLDPDLPEVLadRDQLEQVLINLLKNAIEAIEEGGEIEVSTRREDGR 349
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 90111458 397 VYIDVINTGTPIPQEERAMIFEPFFqgSHQRkgavKGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIELP 469
Cdd:COG5000 350 VRIEVSDNGPGIPEEVLERIFEPFF--TTKP----KGTGLGLAIVKKIVEEHGGTIELESRPGGGTTFTIRLP 416
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
360-469 |
1.16e-27 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 106.19 E-value: 1.16e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 360 AEPMLLMSVLDNLYSNAVHYGAESGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFQGShQRKGAVKGSGLGLS 439
Cdd:smart00387 1 GDPDRLRQVLSNLLDNAIKYTPEGGRITVTLERDGDHVEITVEDNGPGIPPEDLEKIFEPFFRTD-KRSRKIGGTGLGLS 79
|
90 100 110
....*....|....*....|....*....|
gi 90111458 440 IARDCIRRMQGELYLVDESGQDVCFRIELP 469
Cdd:smart00387 80 IVKKLVELHGGEISVESEPGGGTTFTITLP 109
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
255-469 |
1.96e-26 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 113.20 E-value: 1.96e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 255 RHL---SHELKTPLASMREGTELLADqvvGPLTPEQKEVVSILDSSSRNLQKLIEQLLDYNRKQADS-AVELENVELAPL 330
Cdd:PRK15347 400 EHLttiSHEIRTPLNGVLGALELLQN---TPLTAEQMDLADTARQCTLSLLAIINNLLDFSRIESGQmTLSLEETALLPL 476
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 331 VETVVSAHSLPARAK--MMHT----DVDLKAtacLAEPMLLMSVLDNLYSNAVHYgAESGNICLRSSLHGARVYIDVINT 404
Cdd:PRK15347 477 LDQAMLTIQGPAQSKslTLRTfvgaHVPLYL---HLDSLRLRQILVNLLGNAVKF-TETGGIRLRVKRHEQQLCFTVEDT 552
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 90111458 405 GTPIPQEERAMIFEPFFQGSHQRKGavkgSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIELP 469
Cdd:PRK15347 553 GCGIDIQQQQQIFTPFYQADTHSQG----TGLGLTIASSLAKMMGGELTLFSTPGVGSCFSLVLP 613
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
1-469 |
1.55e-24 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 106.41 E-value: 1.55e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 1 MKRWPVFPRSLRQLVMLAFLLILLPLLVLAWQAWQSLNALSDQAALVNRTTLIDARRSEAMTNAALEMERSYRQYCVLDD 80
Cdd:COG4251 45 LLLIRLLLLLLLSLLALLLLLLLLLLLLLVLAALALLLLLLLLELALVLLALLLVLLLLLALLLLLALLLLLELLLLLLA 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 81 PTLAKVYQSQRKRYSEMLDAHAGVLPDDKLYQALRQDLHNLAQLQCNNSGPDAAAAARLEAFASANTEMVQATRTVVFSR 160
Cdd:COG4251 125 LLLLLLLLALLLLEELALLRLALALLLLLLLLLLLLLLLLALILALLLAALAELELLLLLLLVLLLLLLLLLLLLLLLLR 204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 161 GQQLQREIAERGQYFGWQSLVLFLVSLVMVLLFTRMIIGPVKNIERMINRLGEGRslgnsvsfsgpsELRSVGQRILWLS 240
Cdd:COG4251 205 LLLELLLLLEAELLLSLGGGLGLLLLLLLLLVLLLLLILLLLLLILVLELLELRL------------ELEELEEELEERT 272
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 241 ERLSWLESQRHQFLRHLSHELKTPLASMREGTELLADQVVGPLTPEQKEVVSILDSSSRNLQKLIEQLLDYNRkQADSAV 320
Cdd:COG4251 273 AELERSNEELEQFAYVASHDLREPLRKISGFSQLLEEDYGDKLDEEGREYLERIRDAAERMQALIDDLLAYSR-VGRQEL 351
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 321 ELENVELAPLVETVVSAHSLPARAKMMHTDVDlKATACLAEPMLLMSVLDNLYSNAVHYGA--ESGNICLRSSLHGARVY 398
Cdd:COG4251 352 EFEPVDLNELLEEVLEDLEPRIEERGAEIEVG-PLPTVRGDPTLLRQVFQNLISNAIKYSRpgEPPRIEIGAEREGGEWV 430
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 90111458 399 IDVINTGTPIPQEERAMIFEPFfqgshQR---KGAVKGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIELP 469
Cdd:COG4251 431 FSVRDNGIGIDPEYAEKIFEIF-----QRlhsRDEYEGTGIGLAIVKKIVERHGGRIWVESEPGEGATFYFTLP 499
|
|
| cpxA |
PRK09470 |
envelope stress sensor histidine kinase CpxA; |
180-450 |
1.51e-22 |
|
envelope stress sensor histidine kinase CpxA;
Pssm-ID: 236532 [Multi-domain] Cd Length: 461 Bit Score: 100.01 E-value: 1.51e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 180 LVLFLVSLVMVLLFTRMIIGPVKNIERMINRLGEGRSLGNSVSFSGPSELRSVGQRILWLSERLSWLESQRHQFLRHLSH 259
Cdd:PRK09470 173 LVTMLVSTPLLLWLAWSLAKPARKLKNAADEVAQGNLRQHPELETGPQEFRQAGASFNQMVTALERMMTSQQRLLSDISH 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 260 ELKTPLASMREGTELLADQVvGpltpEQKEVVSIlDSSSRNLQKLIEQLLDYNRKQADSAVELENVELAPLVETVVSAHS 339
Cdd:PRK09470 253 ELRTPLTRLQLATALLRRRQ-G----ESKELERI-ETEAQRLDSMINDLLVLSRNQQKNHLERETFKANSLWSEVLEDAK 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 340 LPA--RAKMMHTDVDLKATACLAEPMLLMSVLDNLYSNAVHYGAESgnICLRSSLHGARVYIDVINTGTPIPQEERAMIF 417
Cdd:PRK09470 327 FEAeqMGKSLTVSAPPGPWPINGNPNALASALENIVRNALRYSHTK--IEVAFSVDKDGLTITVDDDGPGVPEEEREQIF 404
|
250 260 270
....*....|....*....|....*....|...
gi 90111458 418 EPFFQGSHQRKGAVKGSGLGLSIARDCIRRMQG 450
Cdd:PRK09470 405 RPFYRVDEARDRESGGTGLGLAIVENAIQQHRG 437
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
362-469 |
1.34e-21 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 89.35 E-value: 1.34e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 362 PMLLMSVLDNLYSNAVHYGAESGNICLRSSlHGARVYIDVINTGTPIPQEERAMIFEPFFQGSHQRKGavkGSGLGLSIA 441
Cdd:pfam02518 3 ELRLRQVLSNLLDNALKHAAKAGEITVTLS-EGGELTLTVEDNGIGIPPEDLPRIFEPFSTADKRGGG---GTGLGLSIV 78
|
90 100
....*....|....*....|....*...
gi 90111458 442 RDCIRRMQGELYLVDESGQDVCFRIELP 469
Cdd:pfam02518 79 RKLVELLGGTITVESEPGGGTTVTLTLP 106
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
253-469 |
3.46e-21 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 96.90 E-value: 3.46e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 253 FLRHLSHELKTPLASMREGTELLADQvvgPLTPEQKEVVSILDSSSRNLQKLIEQLLDYNRKQADS---AVELENVELAP 329
Cdd:PRK11466 447 FLAAMSHEIRTPLYGILGTAQLLADN---PALNAQRDDLRAITDSGESLLTILNDILDYSAIEAGGknvSVSDEPFEPRP 523
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 330 LVETVVSAHSLPARAKMMHTDVDLK---ATACLAEPMLLMSVLDNLYSNAVHYgAESGNICLRSSLHGARVYIDVINTGT 406
Cdd:PRK11466 524 LLESTLQLMSGRVKGRPIRLATDIAddlPTALMGDPRRIRQVITNLLSNALRF-TDEGSIVLRSRTDGEQWLVEVEDSGC 602
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 90111458 407 PIPQEERAMIFEPFFQGSHQRkgavKGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIELP 469
Cdd:PRK11466 603 GIDPAKLAEIFQPFVQVSGKR----GGTGLGLTISSRLAQAMGGELSATSTPEVGSCFCLRLP 661
|
|
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
182-469 |
7.99e-20 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 91.51 E-value: 7.99e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 182 LFLVSLVMVLL-------FTRMIIGPVKNIERMINRLGEGrSLGNSVSFSGPSELRSVGQRILWLSERLSWLESQRHQFL 254
Cdd:PRK09467 155 LFRYTLAIGLLsvaggwlFIRIQNRPLVALEHAALQVGKG-EIPPPLREYGASEVRSVTRAFNQMAAGIKQLEDDRTLLM 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 255 RHLSHELKTPLASMREGTELLAdqvvgpltPEQ---KEvvSIL-DSSSRNlqKLIEQLLDYNRKqaDSAVELENVELAPL 330
Cdd:PRK09467 234 AGVSHDLRTPLTRIRLATEMMS--------EEDgylAE--SINkDIEECN--AIIEQFIDYLRT--GQEMPMEMADLNAL 299
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 331 VETVVSAHSlpARAKMMHTDVDLKATACLAEPMLLMSVLDNLYSNAVHYGaeSGNICLRSSLHGARVYIDVINTGTPIPQ 410
Cdd:PRK09467 300 LGEVIAAES--GYEREIETALQPGPIEVPMNPIAIKRALANLVVNAARYG--NGWIKVSSGTEGKRAWFQVEDDGPGIPP 375
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 90111458 411 EERAMIFEPFFQGSHQRKGAvkGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIELP 469
Cdd:PRK09467 376 EQLKHLFQPFTRGDSARGSS--GTGLGLAIVKRIVDQHNGKVELGNSEEGGLSARAWLP 432
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
362-469 |
4.87e-19 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 82.08 E-value: 4.87e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 362 PMLLMSVLDNLYSNAVHYGAESGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFqgshQRKGAVKGSGLGLSIA 441
Cdd:cd16943 1 PSQLNQVLLNLLVNAAQAMEGRGRITIRTWAHVDQVLIEVEDTGSGIDPEILGRIFDPFF----TTKPVGEGTGLGLSLS 76
|
90 100
....*....|....*....|....*...
gi 90111458 442 RDCIRRMQGELYLVDESGQDVCFRIELP 469
Cdd:cd16943 77 YRIIQKHGGTIRVASVPGGGTRFTIILP 104
|
|
| cztS_silS_copS |
TIGR01386 |
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain ... |
177-469 |
7.83e-19 |
|
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.
Pssm-ID: 273593 [Multi-domain] Cd Length: 457 Bit Score: 88.60 E-value: 7.83e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 177 WQSLVLFLVSLVMVLLFTRMIIGPVKNIERMINRLgEGRSLGNSVSFSG-PSELRSVGQRILWLSERLSWLESQRHQFLR 255
Cdd:TIGR01386 168 LIAVLLVLLTALLGWWITRLGLEPLRRLSAVAARI-SPESLDQRLDPSRaPAELRELAQSFNAMLGRLEDAFQRLSQFSA 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 256 HLSHELKTPLASMREGTELLADQvvgPLTpeQKEVVSILDSSSRNLQKL---IEQLLDYNR-KQADSAVELENVELAPLV 331
Cdd:TIGR01386 247 DLAHELRTPLTNLLGQTQVALSQ---PRT--GEEYREVLESNLEELERLsrmVSDMLFLARaDNGQLALERVRLDLAAEL 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 332 ETVVSAHSLPARAKMMHTDVDLKATAcLAEPMLLMSVLDNLYSNAVHYGAESGNICLRSSLHGARVYIDVINTGTPIPQE 411
Cdd:TIGR01386 322 AKVAEYFEPLAEERGVRIRVEGEGLV-RGDPQMFRRAISNLLSNALRHTPDGGTITVRIERRSDEVRVSVSNPGPGIPPE 400
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 90111458 412 ERAMIFEPFFQGSHQRKGAVKGSGLGLSIARDCIRRMQGELYlVDESGQDVCFRIELP 469
Cdd:TIGR01386 401 HLSRLFDRFYRVDPARSNSGEGTGLGLAIVRSIMEAHGGRAS-AESPDGKTRFILRFP 457
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
184-469 |
8.72e-19 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 88.54 E-value: 8.72e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 184 LVSLVMVLLFTRMIIGPVKNIERMINRLGEGrSLGNSVSFSGPSELRSVGQRILWLSERLSWLESQRHQFLRHLSHELKT 263
Cdd:PRK10549 175 LLAALATFLLARGLLAPVKRLVEGTHKLAAG-DFTTRVTPTSRDELGRLAQDFNQLASTLEKNEQMRRDFMADISHELRT 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 264 PLASMREGTELLADQVVGPlTPEQkevVSILDSSSRNLQKLIEQL----------LDYnRKQAdsavelenVELAPLVET 333
Cdd:PRK10549 254 PLAVLRGELEAIQDGVRKF-TPES---VASLQAEVGTLTKLVDDLhqlslsdegaLAY-RKTP--------VDLVPLLEV 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 334 VVSAHSLPARAKMMHTDVDLKATACL-AEPMLLMSVLDNLYSNAVHYGAESGNICLRSSLHGARVYIDVINTGTPIPQEE 412
Cdd:PRK10549 321 AGGAFRERFASRGLTLQLSLPDSATVfGDPDRLMQLFNNLLENSLRYTDSGGSLHISAEQRDKTLRLTFADSAPGVSDEQ 400
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 90111458 413 RAMIFEPFFQGSHQRKGAVKGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIELP 469
Cdd:PRK10549 401 LQKLFERFYRTEGSRNRASGGSGLGLAICLNIVEAHNGRIIAAHSPFGGVSITVELP 457
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
259-469 |
9.43e-19 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 89.26 E-value: 9.43e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 259 HELKTPLASMREGTELLADQVVGPLTPEQ-----KEVvsildsssRNLQKLIEQLLDYNRKqadSAVELENVELAPLVET 333
Cdd:PRK11360 399 HEIRNPLTAIRGYVQIWRQQTSDPPSQEYlsvvlREV--------DRLNKVIDQLLEFSRP---RESQWQPVSLNALVEE 467
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 334 VV-----SAHSlpARAKMmHTDVDLKATACLAEPMLLMSVLDNLYSNAVHYGAESGNICLRSSLHGA-RVYIDVINTGTP 407
Cdd:PRK11360 468 VLqlfqtAGVQ--ARVDF-ETELDNELPPIWADPELLKQVLLNILINAVQAISARGKIRIRTWQYSDgQVAVSIEDNGCG 544
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 90111458 408 IPQEERAMIFEPFFQGShqrkgaVKGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIELP 469
Cdd:PRK11360 545 IDPELLKKIFDPFFTTK------AKGTGLGLALSQRIINAHGGDIEVESEPGVGTTFTLYLP 600
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
368-469 |
2.37e-18 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 80.23 E-value: 2.37e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 368 VLDNLYSNAVHYGAEsGNICLRSSL-----HGARVYIDVINTGTPIPQEERAMIFEPFFQGSHQRKGAVKGSGLGLSIAR 442
Cdd:cd16922 4 ILLNLLGNAIKFTEE-GEVTLRVSLeeeeeDGVQLRFSVEDTGIGIPEEQQARLFEPFSQADSSTTRKYGGTGLGLAISK 82
|
90 100
....*....|....*....|....*..
gi 90111458 443 DCIRRMQGELYLVDESGQDVCFRIELP 469
Cdd:cd16922 83 KLVELMGGDISVESEPGQGSTFTFTLP 109
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
204-473 |
3.53e-18 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 86.58 E-value: 3.53e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 204 IERMINRLGEGRsLGNSVSFSGPSELRSVGQRILWLSERLSWLESQRHQFLRHLSHELKTPLASMREGTELLADqvvgPL 283
Cdd:PRK10604 167 LEAAAQRLGDGH-LAERIHFDEGSSLERLGVAFNQMADNINALIASKKQLIDGIAHELRTPLVRLRYRLEMSDN----LS 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 284 TPEQKEVVSILDSssrnLQKLIEQLLDY---NRKQADsaVELENVELAPLVETVVSAHSLPARAKMMHTDVDLKATACLA 360
Cdd:PRK10604 242 AAESQALNRDIGQ----LEALIEELLTYarlDRPQNE--LHLSEPDLPAWLSTHLADIQAVTPEKTVRLDTPHQGDYGAL 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 361 EPMLLMSVLDNLYSNAVHYGAesGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFQGSHQRKGAVKGSGLGLSI 440
Cdd:PRK10604 316 DMRLMERVLDNLLNNALRYAH--SRVRVSLLLDGNQACLIVEDDGPGIPPEERERVFEPFVRLDPSRDRATGGCGLGLAI 393
|
250 260 270
....*....|....*....|....*....|....*.
gi 90111458 441 ARDCIRRMQGELYlVDES---GQDVCFRIELPSSKN 473
Cdd:PRK10604 394 VHSIALAMGGSVN-CDESelgGARFSFSWPVWHNLP 428
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
250-469 |
4.68e-18 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 87.48 E-value: 4.68e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 250 RHQFLRHLSHELKTPLASMREGTELLADQvvgPLTPEQK-EVVSILDSSSRNLQKLIEQLLDYNR-KQADSAVELENVEL 327
Cdd:PRK09959 712 KSQFLATMSHEIRTPISSIMGFLELLSGS---GLSKEQRvEAISLAYATGQSLLGLIGEILDVDKiESGNYQLQPQWVDI 788
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 328 APLVETvvSAHSLPARAKMMHTDVDLKAT-----ACLAEPMLLMSVLDNLYSNAVHYGAEsGNICLRSSL-----HGARV 397
Cdd:PRK09959 789 PTLVQN--TCHSFGAIAASKSIALSCSSTfpdhyLVKIDPQAFKQVLSNLLSNALKFTTE-GAVKITTSLghiddNHAVI 865
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 90111458 398 YIDVINTGTPIPQEERAMIFEPFFQGSHQRKGAvkGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIELP 469
Cdd:PRK09959 866 KMTIMDSGSGLSQEEQQQLFKRYSQTSAGRQQT--GSGLGLMICKELIKNMQGDLSLESHPGIGTTFTITIP 935
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
240-469 |
2.65e-17 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 85.09 E-value: 2.65e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 240 SERLSWLESQRHQ----FLRHLSHELKTPLASMREGTELL-----ADQvvGPLTPEQKEVVSILDSSSRnlqkLIEQLLD 310
Cdd:PRK10490 650 SEEQARLASEREQlrnaLLAALSHDLRTPLTVLFGQAEILtldlaSEG--SPHARQASEIRQQVLNTTR----LVNNLLD 723
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 311 YNRKQADsAVELeNVELAPLVETVVSA-HSLPARAKMMHTDVDLKATACL--AEPMLLMSVLDNLYSNAVHYGAESGNIC 387
Cdd:PRK10490 724 MARIQSG-GFNL-RKEWLTLEEVVGSAlQMLEPGLSGHPINLSLPEPLTLihVDGPLFERVLINLLENAVKYAGAQAEIG 801
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 388 LRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFQGshQRKGAVKGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIE 467
Cdd:PRK10490 802 IDAHVEGERLQLDVWDNGPGIPPGQEQLIFDKFARG--NKESAIPGVGLGLAICRAIVEVHGGTIWAENRPEGGACFRVT 879
|
..
gi 90111458 468 LP 469
Cdd:PRK10490 880 LP 881
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
240-473 |
3.16e-16 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 80.79 E-value: 3.16e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 240 SERLSWLEsqrhQFLRHLSHELKTPLASMREGTELLADQVvgplTPEQKEVVSILDSSSRNLQKLIEQLLDYNRKQAdsa 319
Cdd:COG5809 264 SEKLSVVG----ELAAGIAHEIRNPLTSLKGFIQLLKDTI----DEEQKTYLDIMLSELDRIESIISEFLVLAKPQA--- 332
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 320 VELENVELAPLVETVVSAhsLPARAkmMHTDVDLKATACLAEPMLLMS------VLDNLYSNAVHYGAESGNICLRSSLH 393
Cdd:COG5809 333 IKYEPKDLNTLIEEVIPL--LQPQA--LLKNVQIELELEDDIPDILGDenqlkqVFINLLKNAIEAMPEGGNITIETKAE 408
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 394 -GARVYIDVINTGTPIPQEERAMIFEPFFQGSHqrkgavKGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIELPSSK 472
Cdd:COG5809 409 dDDKVVISVTDEGCGIPEERLKKLGEPFYTTKE------KGTGLGLMVSYKIIEEHGGKITVESEVGKGTTFSITLPIKL 482
|
.
gi 90111458 473 N 473
Cdd:COG5809 483 S 483
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
368-469 |
3.98e-16 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 73.64 E-value: 3.98e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 368 VLDNLYSNAVHYGaeSGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFQGSHQRkgAVKGSGLGLSIARDCIRR 447
Cdd:cd16950 4 VLSNLVDNALRYG--GGWVEVSSDGEGNRTRIQVLDNGPGIAPEEVDELFQPFYRGDNAR--GTSGTGLGLAIVQRISDA 79
|
90 100
....*....|....*....|..
gi 90111458 448 MQGELYLVDESGQDVCFRIELP 469
Cdd:cd16950 80 HGGSLTLANRAGGGLCARIELP 101
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
213-469 |
1.42e-15 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 78.35 E-value: 1.42e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 213 EGRSLGNSVSFSGPSELRSvgqrilwLSERLSWLESQRHQfLRHLSHELKTPLASMREGTELLADQvvgpltpeqkEVVS 292
Cdd:COG3290 160 DGRVVGAVATFRDRTELER-------LEEELEGVKELAEA-LRAQRHDFRNHLHTISGLLQLGEYD----------EALE 221
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 293 ILDSSSRNLQKLIEQLLDYnrkqadsaveLENVELAPLVETVVSahslpaRAKMMHTDVDLKATACLAE----PMLLMSV 368
Cdd:COG3290 222 YIDEISEELQELIDSLLSR----------IGNPVLAALLLGKAA------RARERGIDLTIDIDSDLPDlplsDTDLVTI 285
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 369 LDNLYSNAVHY----GAESGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFF--QGSHqrkgavkGSGLGLSIAR 442
Cdd:COG3290 286 LGNLLDNAIEAveklPEEERRVELSIRDDGDELVIEVEDSGPGIPEELLEKIFERGFstKLGE-------GRGLGLALVK 358
|
250 260
....*....|....*....|....*..
gi 90111458 443 DCIRRMQGELYLVDESGQDVCFRIELP 469
Cdd:COG3290 359 QIVEKYGGTIEVESEEGEGTVFTVRLP 385
|
|
| PRK10841 |
PRK10841 |
two-component system sensor histidine kinase RcsC; |
253-469 |
3.52e-15 |
|
two-component system sensor histidine kinase RcsC;
Pssm-ID: 182772 [Multi-domain] Cd Length: 924 Bit Score: 78.48 E-value: 3.52e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 253 FLRHLSHELKTPLASMREGTELLADQVvgpLTPEQKEVVSILDSSSRNLQKLIEQLLDYNR---KQadsaVELENVELAP 329
Cdd:PRK10841 450 FLATVSHELRTPLYGIIGNLDLLQTKE---LPKGVDRLVTAMNNSSSLLLKIISDILDFSKiesEQ----LKIEPREFSP 522
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 330 L-VETVVSAHSLPARAK-------MMHTDVDLkatACLAEPMLLMSVLDNLYSNAVHYgAESGNICLRSSLHGARVYIDV 401
Cdd:PRK10841 523 ReVINHITANYLPLVVKkrlglycFIEPDVPV---ALNGDPMRLQQVISNLLSNAIKF-TDTGCIVLHVRVDGDYLSFRV 598
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 90111458 402 INTGTPIPQEERAMIFEPFFQGSHQRKGAVKGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIELP 469
Cdd:PRK10841 599 RDTGVGIPAKEVVRLFDPFFQVGTGVQRNFQGTGLGLAICEKLINMMDGDISVDSEPGMGSQFTIRIP 666
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
365-469 |
1.04e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 69.66 E-value: 1.04e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 365 LMSVLDNLYSNAVHYGAESgnICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFQGSHQRKGAVKGSGLGLSIARDC 444
Cdd:cd16949 1 LARALENVLRNALRYSPSK--ILLDISQDGDQWTITITDDGPGVPEDQLEQIFLPFYRVDSARDRESGGTGLGLAIAERA 78
|
90 100
....*....|....*....|....*
gi 90111458 445 IRRMQGELYLVDESGQDVCFRIELP 469
Cdd:cd16949 79 IEQHGGKIKASNRKPGGLRVRIWLP 103
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
246-470 |
2.24e-14 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 74.66 E-value: 2.24e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 246 LESQRHQFLRHLSHELKTPLASMREGTELLADQV-VGPLtpeQKEVVSILDSSSRNLQKLIEQLLDYNRKQADSAVELEN 324
Cdd:PRK11006 200 LEGARRNFFANVSHELRTPLTVLQGYLEMMQDQPlEGAL---REKALHTMREQTQRMEGLVKQLLTLSKIEAAPTIDLNE 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 325 VELAPLVETVV--SAHSLPARAKMMHTDVDlKATACLAEPMLLMSVLDNLYSNAVHYGAESGNI--CLRSSLHGARvyID 400
Cdd:PRK11006 277 KVDVPMMLRVLerEAQTLSQGKHTITFEVD-NSLKVFGNEDQLRSAISNLVYNAVNHTPEGTHItvRWQRVPQGAE--FS 353
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 401 VINTGTPIPQEERAMIFEPFFQGSHQRKGAVKGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIELPS 470
Cdd:PRK11006 354 VEDNGPGIAPEHIPRLTERFYRVDKARSRQTGGSGLGLAIVKHALSHHDSRLEIESEVGKGTRFSFVLPE 423
|
|
| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
150-475 |
2.90e-14 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 73.85 E-value: 2.90e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 150 VQATRTVVfSRGQQLQREIAErgqyfgwQSLVLFLVSLVMVLLFTRMIIGPVKNIERMINRLG---EGRSLGN---SVSF 223
Cdd:PRK10755 39 VQATLSAR-NNDEHVMKEIRE-------AVASLLVPSLVMVSLTLLICFQAVRWITRPLAELQkelEARTADNltpIAIH 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 224 SGPSELRSVGQRILWLSERLSWLESQRHQFLRHLSHELKTPLASMREGTELLADQVVgpltPEQKEVVSILDSssrnLQK 303
Cdd:PRK10755 111 SSTLEIEAVTSALNQLVSRLTSTLDQERLFTADVAHELRTPLAGIRLHLELLEKQHH----IDVAPLIARLDQ----MMH 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 304 LIEQLLDYNR-KQADSAVELENVElapLVETVVsahsLPARAKM--MHT----DVDLKATACLA----EPMLLMSVLDNL 372
Cdd:PRK10755 183 TVEQLLQLARaGQSFSSGHYQTVK---LLEDVI----LPSQDELseMLEqrqqTLLLPESAADItvqgDATLLRLLLRNL 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 373 YSNAVHYGAESGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFQgSHQRKGavkGSGLGLSIARDCIRRMQGEL 452
Cdd:PRK10755 256 VENAHRYSPEGSTITIKLSQEDGGAVLAVEDEGPGIDESKCGELSKAFVR-MDSRYG---GIGLGLSIVSRITQLHHGQF 331
|
330 340
....*....|....*....|....*.
gi 90111458 453 YL---VDESGQDVCfrIELPSSKNTK 475
Cdd:PRK10755 332 FLqnrQERSGTRAW--VWLPKAQNVA 355
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
239-469 |
3.74e-14 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 73.83 E-value: 3.74e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 239 LSERLSWLEsqrhQFLRHLSHELKTPL--ASMR-EGTELLADQVVGPLTPEQKEvvSILDSSSRNLQK---LIEQLLDYN 312
Cdd:PRK09303 144 LLEQLKFKD----RVLAMLAHDLRTPLtaASLAlETLELGQIDEDTELKPALIE--QLQDQARRQLEEierLITDLLEVG 217
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 313 R-KQADSAVELENVELAPLVETVVS--AHSLPARAKMMHTDVDLKATACLAEPMLLMSVLDNLYSNAVHYGAESGNICLr 389
Cdd:PRK09303 218 RtRWEALRFNPQKLDLGSLCQEVILelEKRWLAKSLEIQTDIPSDLPSVYADQERIRQVLLNLLDNAIKYTPEGGTITL- 296
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 390 SSLH--GARVYIDVINTGTPIPQEERAMIFEPFFQgsHQRKGAVKGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIE 467
Cdd:PRK09303 297 SMLHrtTQKVQVSICDTGPGIPEEEQERIFEDRVR--LPRDEGTEGYGIGLSVCRRIVRVHYGQIWVDSEPGQGSCFHFT 374
|
..
gi 90111458 468 LP 469
Cdd:PRK09303 375 LP 376
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
368-469 |
7.57e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 67.41 E-value: 7.57e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 368 VLDNLYSNAVHYGAESGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFQGSHQRKGAvkGSGLGLSIARDCIRR 447
Cdd:cd16923 4 VFSNLLSNAIKYSPENTRIYITSFLTDDVVNIMFKNPSSHPLDFKLEKLFERFYRGDNSRNTE--GAGLGLSIAKAIIEL 81
|
90 100
....*....|....*....|..
gi 90111458 448 MQGELYLVDESGQDVcFRIELP 469
Cdd:cd16923 82 HGGSASAEYDDNHDL-FKVRLP 102
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
249-316 |
7.77e-14 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 66.08 E-value: 7.77e-14
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 90111458 249 QRHQFLRHLSHELKTPLASMREGTELLADqvvGPLTPEQKEVVSILDSSSRNLQKLIEQLLDYNRKQA 316
Cdd:pfam00512 1 AKSEFLANLSHELRTPLTAIRGYLELLRD---EKLDEEQREYLETILRSAERLLRLINDLLDLSRIEA 65
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
258-469 |
1.08e-13 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 72.90 E-value: 1.08e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 258 SHELKTPLASMREGTELLADQVvgPLTPEQKEVVSILDSSSRNLQKLIEQLLDYNRKqadSAVELENVELAPLVETVVSA 337
Cdd:PRK10364 245 AHEIRNPLSSIKGLAKYFAERA--PAGGEAHQLAQVMAKEADRLNRVVSELLELVKP---THLALQAVDLNDLINHSLQL 319
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 338 HSLPARAKMMhtDVDLKATACL----AEPMLLMSVLDNLYSNAVHYGAESGNICLRSSLHGARVYIDVINTGTPIPQEER 413
Cdd:PRK10364 320 VSQDANSREI--QLRFTANDTLpeiqADPDRLTQVLLNLYLNAIQAIGQHGVISVTASESGAGVKISVTDSGKGIAADQL 397
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 90111458 414 AMIFEPFFQGSHQrkgavkGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIELP 469
Cdd:PRK10364 398 EAIFTPYFTTKAE------GTGLGLAVVHNIVEQHGGTIQVASQEGKGATFTLWLP 447
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
249-316 |
1.16e-13 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 65.67 E-value: 1.16e-13
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 90111458 249 QRHQFLRHLSHELKTPLASMREGTELLADqvvGPLTPEQKEVVSILDSSSRNLQKLIEQLLDYNRKQA 316
Cdd:smart00388 1 AKREFLANLSHELRTPLTAIRGYLELLLD---TELSEEQREYLETILREAERLLRLINDLLDLSRIEA 65
|
|
| PRK11107 |
PRK11107 |
hybrid sensory histidine kinase BarA; Provisional |
253-469 |
1.45e-13 |
|
hybrid sensory histidine kinase BarA; Provisional
Pssm-ID: 236848 [Multi-domain] Cd Length: 919 Bit Score: 73.34 E-value: 1.45e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 253 FLRHLSHELKTPLasmregtellaDQVVG--------PLTPEQKEVVSILDSSSRNLQKLIEQLLDYNRKQADsAVELEN 324
Cdd:PRK11107 296 FLANMSHELRTPL-----------NGVIGftrqtlktPLTPTQRDYLQTIERSANNLLAIINDILDFSKLEAG-KLVLEN 363
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 325 V--ELAPLVETVVS--AHSlpARAKMMHTDVDLKAT---ACLAEPMLLMSVLDNLYSNAVHYgAESGNICLRSSLHGAR- 396
Cdd:PRK11107 364 IpfSLRETLDEVVTllAHS--AHEKGLELTLNIDPDvpdNVIGDPLRLQQIITNLVGNAIKF-TESGNIDILVELRALSn 440
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 397 ----VYIDVINTGTPIPQEERAMIFEPFFQG--SHQRK-GavkGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIELP 469
Cdd:PRK11107 441 tkvqLEVQIRDTGIGISERQQSQLFQAFRQAdaSISRRhG---GTGLGLVITQKLVNEMGGDISFHSQPNRGSTFWFHLP 517
|
|
| HATPase_YcbM-like |
cd16947 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
348-468 |
3.08e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).
Pssm-ID: 340423 [Multi-domain] Cd Length: 125 Bit Score: 66.38 E-value: 3.08e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 348 HTDVDLKATACLAEPMLLMSVLDNLYSNAVHYGAESGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFQGSHQR 427
Cdd:cd16947 4 EINIPDRPIYANANTEALQRILKNLISNAIKYGSDGKFLGMTLREDEKHVYIDIWDKGKGISETEKDHVFERLYTLEDSR 83
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 90111458 428 KGAVKGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIEL 468
Cdd:cd16947 84 NSAKQGNGLGLTITKRLAESMGGSIYVNSKPYEKTVFTVTL 124
|
|
| PRK11091 |
PRK11091 |
aerobic respiration control sensor protein ArcB; Provisional |
253-469 |
3.25e-13 |
|
aerobic respiration control sensor protein ArcB; Provisional
Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 71.90 E-value: 3.25e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 253 FLRHLSHELKTPLASMREGTELLADQvvgPLTPEQKEVVSILDSSSRNLQKLIEQLLDYNrKQADSAVELEN--VELAPL 330
Cdd:PRK11091 286 FISTISHELRTPLNGIVGLSRILLDT---ELTAEQRKYLKTIHVSAITLGNIFNDIIDMD-KMERRKLQLDNqpIDFTDF 361
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 331 VETVVSAHSLPARAK----MMHTDVDLKATAClAEPMLLMSVLDNLYSNAVHYGAEsGNICLRSSLH-GARVYIDVINTG 405
Cdd:PRK11091 362 LADLENLSGLQAEQKglrfDLEPLLPLPHKVI-TDGTRLRQILWNLISNAVKFTQQ-GGVTVRVRYEeGDMLTFEVEDSG 439
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 90111458 406 TPIPQEERAMIFEPFFQ--GSHQRKGAVkGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIELP 469
Cdd:PRK11091 440 IGIPEDELDKIFAMYYQvkDSHGGKPAT-GTGIGLAVSKRLAQAMGGDITVTSEEGKGSCFTLTIH 504
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
368-469 |
3.62e-13 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 65.59 E-value: 3.62e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 368 VLDNLYSNAVHYGAESGNI-CLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFQGSHQRKGAVKGSGLGLSIARDCIR 446
Cdd:cd16925 8 VVLNLLSNAFKFTPDGGRIrCILEKFRLNRFLLTVSDSGPGIPPNLREEIFERFRQGDGSSTRAHGGTGLGLSIVKEFVE 87
|
90 100
....*....|....*....|...
gi 90111458 447 RMQGELYLVDESGQDVCFRIELP 469
Cdd:cd16925 88 LHGGTVTVSDAPGGGALFQVELP 110
|
|
| glnL |
PRK11073 |
nitrogen regulation protein NR(II); |
228-469 |
1.29e-12 |
|
nitrogen regulation protein NR(II);
Pssm-ID: 182947 [Multi-domain] Cd Length: 348 Bit Score: 68.95 E-value: 1.29e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 228 ELRSVGQRilwlsERLSWLESQRHQ------FLRHLSHELKTPLASMREGTELLADQVVGPLTPEQKEVvsILDSSSRnL 301
Cdd:PRK11073 107 EMAPMDNQ-----RRLSQEQLQHAQqvaardLVRGLAHEIKNPLGGLRGAAQLLSKALPDPALTEYTKV--IIEQADR-L 178
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 302 QKLIEQLLDYNR---KQADSavelenveLAPLVETVVSAHSLPARAKM-MHTDVDLKATACLAEPMLLMSVLDNLYSNAV 377
Cdd:PRK11073 179 RNLVDRLLGPQRpgtHVTES--------IHKVAERVVQLVSLELPDNVrLIRDYDPSLPELAHDPDQIEQVLLNIVRNAL 250
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 378 H-YGAESGNICLRS------SLHGAR----VYIDVINTGTPIPQEERAMIFEPFFQGshqRKGavkGSGLGLSIARDCIR 446
Cdd:PRK11073 251 QaLGPEGGTITLRTrtafqlTLHGERyrlaARIDIEDNGPGIPPHLQDTLFYPMVSG---REG---GTGLGLSIARNLID 324
|
250 260
....*....|....*....|...
gi 90111458 447 RMQGELYLVDESGQDVcFRIELP 469
Cdd:PRK11073 325 QHSGKIEFTSWPGHTE-FSVYLP 346
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
247-313 |
4.86e-12 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 61.07 E-value: 4.86e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 90111458 247 ESQRHQFLRHLSHELKTPLASMREGTELLADQVVGPltPEQKEVVSILDSSSRNLQKLIEQLLDYNR 313
Cdd:cd00082 1 LQAKGEFLANVSHELRTPLTAIRGALELLEEELLDD--EEQREYLERIREEAERLLRLINDLLDLSR 65
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
179-442 |
1.10e-11 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 66.60 E-value: 1.10e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 179 SLVLFLVSL-VMVLLFTRMIIGPVKNIERMINRLgEGRSLGNSVSFSG---PSELRSVGQRILWLSERLSWLESQRHQFL 254
Cdd:PRK10337 163 QLIPWLVALpIMLIILMVLLGRELAPLKKLALAL-RMRDPDSETPLNAtgvPSEVRPLVEALNQLFARTHAMMVRERRFT 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 255 RHLSHELKTPLASMREGTELLadQVVGPLTPEQKEVVSILDSSSRNLQKLIEQLLDYNRKQADSAV-ELENVELAPLVET 333
Cdd:PRK10337 242 SDAAHELRSPLAALKVQTEVA--QLSDDDPQARKKALLQLHAGIDRATRLVDQLLTLSRLDSLDNLqDVAEIPLEDLLQS 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 334 VVSAHSLPARAKMMHTDVDLKATACL--AEPMLLMSVLDNLYSNAVHYGAESGNICLRSSLHGARvyidVINTGTPIPQE 411
Cdd:PRK10337 320 AVMDIYHTAQQAGIDVRLTLNAHPVIrtGQPLLLSLLVRNLLDNAIRYSPQGSVVDVTLNARNFT----VRDNGPGVTPE 395
|
250 260 270
....*....|....*....|....*....|.
gi 90111458 412 ERAMIFEPFFQGSHQRKgavKGSGLGLSIAR 442
Cdd:PRK10337 396 ALARIGERFYRPPGQEA---TGSGLGLSIVR 423
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
154-468 |
1.31e-11 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 66.19 E-value: 1.31e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 154 RTVVFSRGQQLQREIAERGQYFGWQSLVLFLVSLVMVLLFTRMIIGPVKNIERMINRLGEGRSLgnSVSFSGPSELRSVG 233
Cdd:COG2972 138 TLVSLIPKSELFRGLFSLRRLILLIILLLLLLALLLSYLLSRSITRPIKRLKKAMKKVEKGDLV--RLEVSGNDEIGILA 215
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 234 QRILWLSERLSWLESQRHQFLRHLSH-ELKT------P------LASMREgtelLAdqvvgpLTPEQKEVVSILDSssrn 300
Cdd:COG2972 216 RSFNEMVERIKELIEEVYELELEKKEaELKAlqaqinPhflfntLNSIRW----LA------ELEDPEEAEEMLEA---- 281
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 301 lqkLIEqLLDYNRKQADSAVELENvELApLVETVVSAHSLPARAKM-MHTDVDLKATACLAEPMLLMSVLDNlysnAVHY 379
Cdd:COG2972 282 ---LSK-LLRYSLSKGDELVTLEE-ELE-LIKSYLEIQKLRFGDRLeVEIEIDEELLDLLIPKLILQPLVEN----AIEH 351
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 380 GAES----GNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFQGSHqrkgavkGSGLGLSIARDCIRRMQGELYLV 455
Cdd:COG2972 352 GIEPkeggGTIRISIRKEGDRLVITVEDNGVGMPEEKLEKLLEELSSKGE-------GRGIGLRNVRERLKLYYGEEYGL 424
|
330
....*....|....
gi 90111458 456 D-ESGQDVCFRIEL 468
Cdd:COG2972 425 EiESEPGEGTTVTI 438
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
253-452 |
4.12e-11 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 64.79 E-value: 4.12e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 253 FLRHLSHELKTPLASMREGTELLADQvvgplTPEQKEVVSILDSSSRNLQKLIEQLLDY-NRKQADS-AVELENVELAPL 330
Cdd:PRK09835 265 FSADIAHEIRTPITNLITQTEIALSQ-----SRSQKELEDVLYSNLEELTRMAKMVSDMlFLAQADNnQLIPEKKMLDLA 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 331 VETVVSAHSLPARAKMMHTDVDLKATACLAE--PMLLMSVLDNLYSNAVHYGAESGNICLRSSLHGARVYIDVINTGTPI 408
Cdd:PRK09835 340 DEVGKVFDFFEAWAEERGVELRFVGDPCQVAgdPLMLRRAISNLLSNALRYTPAGEAITVRCQEVDHQVQLVVENPGTPI 419
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 90111458 409 PQEERAMIFEPFFQ--GSHQRKGavKGSGLGLSIARDCIRRMQGEL 452
Cdd:PRK09835 420 APEHLPRLFDRFYRvdPSRQRKG--EGSGIGLAIVKSIVVAHKGTV 463
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
365-468 |
7.61e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 58.62 E-value: 7.61e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 365 LMSVLDNLYSNA---VHyGAESGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFQgshqRKGAVKGSGLGLSIA 441
Cdd:cd16976 1 IQQVLMNLLQNAldaMG-KVENPRIRIAARRLGGRLVLVVRDNGPGIAEEHLSRVFDPFFT----TKPVGKGTGLGLSIS 75
|
90 100
....*....|....*....|....*..
gi 90111458 442 RDCIRRMQGELYLVDESGQDVCFRIEL 468
Cdd:cd16976 76 YGIVEEHGGRLSVANEEGAGARFTFDL 102
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
257-471 |
7.96e-11 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 64.31 E-value: 7.96e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 257 LSHELKTPLASMREGTELlADQVVGPLTPEQKEVVSILDSSSRnLQKLIEQLLDYNRKQADSaveLENVELAPLVETVVS 336
Cdd:PRK13837 457 IAHNFNNILGAILGYAEM-ALNKLARHSRAARYIDEIISAGAR-ARLIIDQILAFGRKGERN---TKPFDLSELVTEIAP 531
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 337 --AHSLPARAKMmhtDVDLKA--TACLAEPMLLMSVLDNLYSNAVHYGAESGNICLRSSLH---------------GARV 397
Cdd:PRK13837 532 llRVSLPPGVEL---DFDQDQepAVVEGNPAELQQVLMNLCSNAAQAMDGAGRVDISLSRAklrapkvlshgvlppGRYV 608
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 90111458 398 YIDVINTGTPIPQEERAMIFEPFFQgshQRKGavkGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIELPSS 471
Cdd:PRK13837 609 LLRVSDTGAGIDEAVLPHIFEPFFT---TRAG---GTGLGLATVHGIVSAHAGYIDVQSTVGRGTRFDVYLPPS 676
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
361-454 |
1.60e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 57.86 E-value: 1.60e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 361 EPMLLMSVLDNLYSNAVHYGAESGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFQGSHQRKGAvKGSGLGLSI 440
Cdd:cd16945 1 DPFLLRQAINNLLDNAIDFSPEGGLIALQLEADTEGIELLVFDEGSGIPDYALNRVFERFYSLPRPHSGQ-KSTGLGLAF 79
|
90
....*....|....
gi 90111458 441 ARDCIRRMQGELYL 454
Cdd:cd16945 80 VQEVAQLHGGRITL 93
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
368-469 |
2.95e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 57.30 E-value: 2.95e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 368 VLDNLYSNAVHYGAESGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFQGSHQRKgAVKGSGLGLSIARDCIRR 447
Cdd:cd16948 9 IIGQIVSNALKYSKQGGKIEIYSETNEQGVVLSIKDFGIGIPEEDLPRVFDKGFTGENGRN-FQESTGMGLYLVKKLCDK 87
|
90 100
....*....|....*....|..
gi 90111458 448 MQGELYLVDESGQDVCFRIELP 469
Cdd:cd16948 88 LGHKIDVESEVGEGTTFTITFP 109
|
|
| PRK10815 |
PRK10815 |
two-component system sensor histidine kinase PhoQ; |
144-452 |
4.29e-10 |
|
two-component system sensor histidine kinase PhoQ;
Pssm-ID: 182754 [Multi-domain] Cd Length: 485 Bit Score: 61.57 E-value: 4.29e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 144 SANTEMVQATRTVVFSRGQQLQREIaergQYFGWQSLVLfLVSLVMVL----LFTRMIIGPVKNIERMINRLGEGRSlgN 219
Cdd:PRK10815 163 PATSRLPKLTIVVVDTIPQELQRSY----MVWSWFSYVL-LANLLLVIpllwLAAWWSLRPIEALAKQVRELEEGER--E 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 220 SVSFSGPSELRSVGQR--ILWLSERlswlesQRHQFLR----HLSHELKTPLA-------SMREGTELladqvvgplTPE 286
Cdd:PRK10815 236 QLDPNPPRELTSLVRNlnRLLKNER------ERYTKYRttltDLTHSLKTPLAvlqstlrSLRSGKQM---------SVE 300
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 287 QKEVVsILDSSSRnlqklIEQLLDY--NRK--QADSAV---ELENVelAPLVETVVSAHSLPARAKMMHTDVDLKA-TAC 358
Cdd:PRK10815 301 QAEPI-MLEQISR-----ISQQIGYylHRAsmRSEHNLlsrELHSV--APLLDNLTSALNKVYQRKGVNITLDISPeITF 372
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 359 LAEPMLLMSVLDNLYSNAVHYGAESGNICLRSSLHGARVYIDviNTGTPIPQEERAMIFEpffQGshQRKGAVK-GSGLG 437
Cdd:PRK10815 373 VGEKNDFMEVMGNVLDNACKYCLEFVEISARQTDEHLHIVVE--DDGPGIPESKRELIFD---RG--QRADTLRpGQGLG 445
|
330
....*....|....*
gi 90111458 438 LSIARDCIRRMQGEL 452
Cdd:PRK10815 446 LSVAREITEQYEGKI 460
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
365-472 |
4.65e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 56.83 E-value: 4.65e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 365 LMSVLDNLYSNAVHYGAESGNICLRSSL--HGARvyIDVINTGTPIPQEERAMIFEPFFQGSHQRKGAVKGSGLGLSIAR 442
Cdd:cd16952 1 LRSAFSNLVSNAVKYTPPSDTITVRWSQeeSGAR--LSVEDTGPGIPPEHIPRLTERFYRVDIERCRNTGGTGLGLAIVK 78
|
90 100 110
....*....|....*....|....*....|
gi 90111458 443 DCIRRMQGELYLVDESGQDVCFRIELPSSK 472
Cdd:cd16952 79 HVMSRHDARLLIASELGKGSRFTCLFPSSR 108
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
368-469 |
5.60e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 56.28 E-value: 5.60e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 368 VLDNLYSNAVHYGAESGNICLRssLHGARVYIDVINTGTPIPQEERAMIFEPFFQGSHQRKGAVKGSGLGLSIARDCIRR 447
Cdd:cd16939 4 ALDNLLRNALRYAHRTVRIALL--VSGGRLTLIVEDDGPGIPAAARERVFEPFVRLDPSRDRATGGFGLGLAIVHRVALW 81
|
90 100
....*....|....*....|..
gi 90111458 448 MQGELYLVDESGQDVCFRIELP 469
Cdd:cd16939 82 HGGHVECDDSELGGACFRLTWP 103
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
365-452 |
1.12e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 55.55 E-value: 1.12e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 365 LMSVLDNLYSNAVHYGAESGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFQGSHQRKGAVKGSGLGLSIARDC 444
Cdd:cd16946 5 LQQLFVNLLENSLRYTDTGGKLRIRAAQTPQEVRLDVEDSAPGVSDDQLARLFERFYRVESSRNRASGGSGLGLAICHNI 84
|
....*...
gi 90111458 445 IRRMQGEL 452
Cdd:cd16946 85 ALAHGGTI 92
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
368-469 |
1.71e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 55.10 E-value: 1.71e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 368 VLDNLYSNAV----HYGAESGNICLRSSLHGAR-VYIDVINTGTPIPQEERAMIFEPFFQGShqrkgaVKGSGLGLSIAR 442
Cdd:cd16920 4 VLINLVRNGIeamsEGGCERRELTIRTSPADDRaVTISVKDTGPGIAEEVAGQLFDPFYTTK------SEGLGMGLSICR 77
|
90 100
....*....|....*....|....*..
gi 90111458 443 DCIRRMQGELYLVDESGQDVCFRIELP 469
Cdd:cd16920 78 SIIEAHGGRLSVESPAGGGATFQFTLP 104
|
|
| HATPase_CckA-like |
cd16919 |
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar ... |
394-469 |
2.03e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar to Brucella abortus 2308 CckA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) similar to Brucella abortus 2308 CckA, which is a component of an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival; phosphoryl transfer initiates from the sensor kinase CckA and proceeds via the ChpT phosphotransferase to two regulatory substrates: the DNA-binding response regulator CtrA and the phospho-receiver protein CpdR. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), a REC signal receiver domain, and some contain PAS or PAS and GAF sensor domain(s).
Pssm-ID: 340396 [Multi-domain] Cd Length: 116 Bit Score: 55.08 E-value: 2.03e-09
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 90111458 394 GARVYIDVINTGTPIPQEERAMIFEPFFQgshqRKGAVKGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIELP 469
Cdd:cd16919 45 GNYVCLEVSDTGSGMPAEVLRRAFEPFFT----TKEVGKGTGLGLSMVYGFVKQSGGHLRIYSEPGVGTTVRIYLP 116
|
|
| HATPase_Glnl-NtrB-like |
cd16918 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
365-469 |
2.36e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli GlnL (synonyms NtrB and NRII); This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs), similar to Escherichia coli GlnL/NtrB/NRII HK of the two-component regulatory system (TCS) GlnL/GlnG (NtrB-NtrC, or NRII-NRI), which regulates the transcription of genes encoding metabolic enzymes and permeases in response to carbon and nitrogen status in E. coli and related bacteria. Also included in this family are Rhodobacter capsulatus NtrB, Azospirillum brasilense NtrB, Vibrio alginolyticus NtrB, Rhizobium leguminosarum biovar phaseoli NtrB, and Herbaspirillum seropedicae NtrB. Escherichia coli GlnL/NtrB/NRII is both a kinase and a phosphatase, catalyzing the phosphorylation and dephosphorylation of GlnG/NtrC/NRI. The kinase and phosphatase activities of GlnL/NtrB/NRII are regulated by the PII signal transduction protein, which on binding to GlnL/NtrB/NRII, inhibits the kinase activity of GlnL/NtrB/NRII and activates the GlnL/NtrB/NRII phosphatase activity. Proteins having this HATPase domain also have a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also contain PAS sensor domain(s).
Pssm-ID: 340395 [Multi-domain] Cd Length: 109 Bit Score: 54.71 E-value: 2.36e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 365 LMSVLDNLYSNAVHYGAES-GNICLRSS------LHGAR----VYIDVINTGTPIPQEERAMIFEPFFQGSHQrkgavkG 433
Cdd:cd16918 1 LIQVFLNLVRNAAQALAGSgGEIILRTRtqrqvtLGHPRhrlaLRVSVIDNGPGIPPDLQDTIFYPMVSGREN------G 74
|
90 100 110
....*....|....*....|....*....|....*.
gi 90111458 434 SGLGLSIARDCIRRMQGELYLVDESGQDVcFRIELP 469
Cdd:cd16918 75 TGLGLAIAQNIVSQHGGVIECDSQPGHTV-FSVSLP 109
|
|
| ArsS_fam_HK |
NF038389 |
ArsS family sensor histidine kinase; ArsS in Helicobacter pylori is a sensor histidine kinase ... |
180-441 |
7.51e-09 |
|
ArsS family sensor histidine kinase; ArsS in Helicobacter pylori is a sensor histidine kinase participating in a two-component system that controls the response to acid conditiions encountered during the process of gastric colonization. This HMM identified ArsS itself but also a broader collection of apparent orthologs from closely related non-gastric colonizers such as Helicobacter hepaticus, Campylobacter jejuni and Wolinella succinogenes. See BlastRule NBR014349 for specific identification of ArsS itself, distinguished by a signature His residue that becomes protonated at low pH.
Pssm-ID: 468500 [Multi-domain] Cd Length: 402 Bit Score: 57.55 E-value: 7.51e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 180 LVLFLVS-LVMVLLFTRMI--IGPVKNIERMINRLGEGRSLGNSVSFSGP------SELRSVGQRILWLserlswLESqR 250
Cdd:NF038389 134 IVFFIFLiLLLLILYISVLksLKPLKKLKKQIKKFANGDFDFIKSESNGDeigevaNEFDKAVKKIKAL------NES-R 206
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 251 HQFLRHLSHELKTPLASMREGTELLADqvvgpltPEQKEV-VSI---LDS-----------SSRN---------LQKLIE 306
Cdd:NF038389 207 QLFLRNIMHELKTPITKGRIVAEMLED-------EKQKERlISIferLESlinefakieqlTSKNyklnkkeyrLSDIID 279
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 307 QLLDY---NRKQADSAVELENVelaplvetvvsahslparakMMHTDVDLKATAclaepmllmsvLDNLYSNAVHYgaes 383
Cdd:NF038389 280 EAIDMlmiDDSSVIIKVSLEDF--------------------KLNVDFELFSLA-----------IKNLIDNAIKY---- 324
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 90111458 384 gniclrSSLHGARVYID-----VINTGTPIPqEERAMIFEPFFQGSHQRKgavKGSGLGLSIA 441
Cdd:NF038389 325 ------SPDKKVTIEIKgdkieFKNKGEPLE-EPLEYYFEPFFKGNEKSK---SGFGLGLYIV 377
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
365-469 |
3.29e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 51.42 E-value: 3.29e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 365 LMSVLDNLYSNAVHYGA-ESGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFqgSHQRKGAVKG--SGLGLSIA 441
Cdd:cd16953 1 LGQVLRNLIGNAISFSPpDTGRITVSAMPTGKMVTISVEDEGPGIPQEKLESIFDRFY--TERPANEAFGqhSGLGLSIS 78
|
90 100 110
....*....|....*....|....*....|....
gi 90111458 442 RDCIRRMQGElyLVDESGQD------VCFRIELP 469
Cdd:cd16953 79 RQIIEAHGGI--SVAENHNQpgqvigARFTVQLP 110
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
364-467 |
4.47e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 50.92 E-value: 4.47e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 364 LLMSVLDNLYSNAVHYGAESGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFQGSHQRKGAvKGSGLGLSIARD 443
Cdd:cd16975 4 LLSRALINIISNACQYAPEGGTVSISIYDEEEYLYFEIWDNGHGFSEQDLKKALELFYRDDTSRRSG-GHYGMGLYIAKN 82
|
90 100
....*....|....*....|....
gi 90111458 444 CIRRMQGELYLVDESGQDVCFRIE 467
Cdd:cd16975 83 LVEKHGGSLIIENSQKGGAEVTVK 106
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
368-469 |
1.81e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 49.46 E-value: 1.81e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 368 VLDNLYSNAVHY--GAESGNICLR---SSLHGARVYIDVINTGTPIPQEERAMIFEPFFQGSHqrkgavKGSGLGLSIAR 442
Cdd:cd16944 8 VLTNILKNAAEAieGRPSDVGEVRirvEADQDGRIVLIVCDNGKGFPREMRHRATEPYVTTRP------KGTGLGLAIVK 81
|
90 100
....*....|....*....|....*..
gi 90111458 443 DCIRRMQGELYLVDESGQDVCFRIELP 469
Cdd:cd16944 82 KIMEEHGGRISLSNREAGGACIRIILP 108
|
|
| HATPase_PhoQ-like |
cd16954 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
365-468 |
2.30e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.
Pssm-ID: 340430 [Multi-domain] Cd Length: 135 Bit Score: 49.94 E-value: 2.30e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 365 LMSVLDNLYSNAVHYGAESGNICLRSSLHGARVYIDviNTGTPIPQEERAMIFEPFFQGSHQRKGavkgSGLGLSIARDC 444
Cdd:cd16954 38 LMELLGNLLDNACKWCLEFVEVTARQTDGGLHLIVD--DDGPGVPESQRSKIFQRGQRLDEQRPG----QGLGLAIAKEI 111
|
90 100
....*....|....*....|....
gi 90111458 445 IRRMQGELYLVDESGQDVCFRIEL 468
Cdd:cd16954 112 VEQYGGELSLSDSPLGGARFEVVF 135
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
259-471 |
7.99e-07 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 51.27 E-value: 7.99e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 259 HELKTPLASMREGTELLadqvvgPLTPEQKEVVS--ILDSSSRnLQKLIEQLLDYNRKQADSaVELENV-----ELAPLV 331
Cdd:COG5805 296 HEIRNPLTSIKGFLQLL------QPGIEDKEEYFdiMLSELDR-IESIISEFLALAKPQAVN-KEKENIneliqDVVTLL 367
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 332 ETVVSAHSLPARakMMHTDVDLKAtacLAEPMLLMSVLDNLYSNAVHYGAESGNICLRSSLHGARVYIDVINTGTPIPQE 411
Cdd:COG5805 368 ETEAILHNIQIR--LELLDEDPFI---YCDENQIKQVFINLIKNAIEAMPNGGTITIHTEEEDNSVIIRVIDEGIGIPEE 442
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 412 ERAMIFEPFFQGSHqrkgavKGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIELPSS 471
Cdd:COG5805 443 RLKKLGEPFFTTKE------KGTGLGLMVSYKIIENHNGTIDIDSKVGKGTTFTITLPLS 496
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
361-440 |
3.61e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 45.86 E-value: 3.61e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 361 EPMLLMSVLDNLYSNAVHYGAESGNICLRSSLHGARVYIdVINTGTPIPQEERAMIFEPFFQGSHQrkgAVKGSGLGLSI 440
Cdd:cd16940 10 DALLLFLLLRNLVDNAVRYSPQGSRVEIKLSADDGAVIR-VEDNGPGIDEEELEALFERFYRSDGQ---NYGGSGLGLSI 85
|
|
| PRK13557 |
PRK13557 |
histidine kinase; Provisional |
303-471 |
1.20e-05 |
|
histidine kinase; Provisional
Pssm-ID: 237425 [Multi-domain] Cd Length: 540 Bit Score: 47.74 E-value: 1.20e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 303 KLIEQLLDYNRKQadsavELEN--VELAPLVETVVS--AHSLpARAKMMHTDVDLKATACLAEPMLLMSVLDNLYSNAVH 378
Cdd:PRK13557 218 TLTQQLLAFARKQ-----RLEGrvLNLNGLVSGMGElaERTL-GDAVTIETDLAPDLWNCRIDPTQAEVALLNVLINARD 291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 379 YGAESGNICLRSS---------------LHGARVYIDVINTGTPIPQEERAMIFEPFFqgshQRKGAVKGSGLGLSIARD 443
Cdd:PRK13557 292 AMPEGGRVTIRTRnveiededlamyhglPPGRYVSIAVTDTGSGMPPEILARVMDPFF----TTKEEGKGTGLGLSMVYG 367
|
170 180
....*....|....*....|....*...
gi 90111458 444 CIRRMQGELYLVDESGQDVCFRIELPSS 471
Cdd:PRK13557 368 FAKQSGGAVRIYSEVGEGTTVRLYFPAS 395
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
365-469 |
2.49e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 43.08 E-value: 2.49e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 365 LMSVLDNLYSNAVHYG--AESGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEpFFQGSHQRkGAVKGSGLGLSIAR 442
Cdd:cd16921 1 LGQVLTNLLGNAIKFRrpRRPPRIEVGAEDVGEEWTFYVRDNGIGIDPEYAEKVFG-IFQRLHSR-EEYEGTGVGLAIVR 78
|
90 100
....*....|....*....|....*..
gi 90111458 443 DCIRRMQGELYLVDESGQDVCFRIELP 469
Cdd:cd16921 79 KIIERHGGRIWLESEPGEGTTFYFTLP 105
|
|
| nifL_nitrog |
TIGR02938 |
nitrogen fixation negative regulator NifL; NifL is a modulator of the nitrogen fixation ... |
363-463 |
1.28e-04 |
|
nitrogen fixation negative regulator NifL; NifL is a modulator of the nitrogen fixation positive regulator protein NifA, and is therefore a negative regulator. It binds NifA. NifA and NifL are encoded by adjacent genes. [Central intermediary metabolism, Nitrogen fixation, Regulatory functions, Protein interactions]
Pssm-ID: 131984 [Multi-domain] Cd Length: 494 Bit Score: 44.51 E-value: 1.28e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 363 MLLMSVLDNLYSNAVHYGAESGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFF--QGSHQrkgavKGSGLGLSI 440
Cdd:TIGR02938 390 SLFKALVDNAIEAMNIKGWKRRELSITTALNGDLIVVSILDSGPGIPQDLRYKVFEPFFttKGGSR-----KHIGMGLSV 464
|
90 100
....*....|....*....|...
gi 90111458 441 ARDCIRRMQGeLYLVDESGQDVC 463
Cdd:TIGR02938 465 AQEIVADHGG-IIDLDDDYSEGC 486
|
|
| PRK13559 |
PRK13559 |
hypothetical protein; Provisional |
246-413 |
1.89e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 237427 [Multi-domain] Cd Length: 361 Bit Score: 43.65 E-value: 1.89e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 246 LESQRHQFLRHLSHELKTPLAsmregtelLADQVVGpLTPEQKEVVSILDSSSRNLQKLI---EQLLDynrkqadsAVEL 322
Cdd:PRK13559 166 LEAHERRLAREVDHRSKNVFA--------VVDSIVR-LTGRADDPSLYAAAIQERVQALArahETLLD--------ERGW 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 323 ENVELAPLVETVVSAHSLPA-RAKMMHTDVDLKATAclAEPMLLmsVLDNLYSNAVHYGA---ESGNICL--RSSLHGAR 396
Cdd:PRK13559 229 ETVEVEELIRAQVAPYAPRAtRVAFEGPGIRLGAAS--VQPLGL--VLHELAVNAIKHGAlsaDQGRISIswKPSPEGAG 304
|
170
....*....|....*..
gi 90111458 397 VYIDVINTGTPIPQEER 413
Cdd:PRK13559 305 FRIDWQEQGGPTPPKLA 321
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
303-454 |
2.34e-04 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 43.52 E-value: 2.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 303 KLIEQLLDYNRKQADSAVElenvelAPLVETVVSAHSLPA-RAKM----MHTDVDLKAtacLAEPMLLMSVLDNLYSNAV 377
Cdd:COG4192 486 KIIKSLRQFSRKSDTPLQP------VDLRQVIEQAWELVEsRAKPqqitLHIPDDLMV---QGDQVLLEQVLVNLLVNAL 556
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 90111458 378 HYGAESGNICLRSSLHGARVYIDVINTGTPIPQEERamIFEPFFQGSHQrkgavkGSGLGLSIARDCIRRMQGELYL 454
Cdd:COG4192 557 DAVATQPQISVDLLSNAENLRVAISDNGNGWPLVDK--LFTPFTTTKEV------GLGLGLSICRSIMQQFGGDLYL 625
|
|
| PRK10618 |
PRK10618 |
phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional |
250-469 |
3.18e-04 |
|
phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional
Pssm-ID: 236726 [Multi-domain] Cd Length: 894 Bit Score: 43.38 E-value: 3.18e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 250 RHQFLRHLSHELKTPLASMREgtelLADQVVGPLTPE-QKEVVSILDSSSRNLQKLIE--QLLdyNRKQADS-AVELENV 325
Cdd:PRK10618 450 RKAFLQNIGDELKQPLQSLAQ----LAAQLRQTSDEEqQQPELDQLAEQSDVLVRLVDniQLL--NMLETQDwKPEQELF 523
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 326 ELAPLVETVVSAhSLPA-RAK--MMHTDVDLKATAC-LAEPMLLMSVLDNLYSNAV---HYGAESGNICLRSSlHGARVY 398
Cdd:PRK10618 524 SLQDLIDEVLPE-VLPAiKRKglQLLIHNHLKAEQLrIGDRDALRKILLLLLNYAItttAYGKITLEVDQDES-SPDRLT 601
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 90111458 399 IDVINTGTPIPQEERAMIFEPFFQGSHQRKGAvKGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIELP 469
Cdd:PRK10618 602 IRILDTGAGVSIKELDNLHFPFLNQTQGDRYG-KASGLTFFLCNQLCRKLGGHLTIKSREGLGTRYSIHLK 671
|
|
| HATPase_CheA-like |
cd16916 |
Histidine kinase-like ATPase domain of the chemotaxis protein histidine kinase CheA, and some ... |
344-469 |
7.53e-04 |
|
Histidine kinase-like ATPase domain of the chemotaxis protein histidine kinase CheA, and some hybrid sensor histidine kinases; This family includes the cytoplasmic histidine kinase (HK) CheA, a transmembrane receptor which, together with cytoplasmic adaptor protein (CheW), forms the lattice at the core of the chemosensory array that controls the cellular chemotaxis of motile bacteria and archaea. CheA forms a two-component signal transduction system (TCS) with the response regulator CheY. Proteins having this CheA-like HATPase domain generally also have a histidine-phosphotransfer domain, a histidine kinase homodimeric domain, and a regulatory domain; some are hybrid sensor histidine kinases as they contain a REC signal receiver domain.
Pssm-ID: 340393 [Multi-domain] Cd Length: 178 Bit Score: 40.26 E-value: 7.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 344 AKMMHTDVDLKATAclAEPMLLMSVLDNLYS-------NAVHYGAES------------GNICLRSSLHGARVYIDV--- 401
Cdd:cd16916 13 ARELGKQVELVVEG--EDTELDKSVLEKLADplthllrNAVDHGIEApeerlaagkppeGTITLRAEHQGNQVVIEVsdd 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 402 -------------INTGTPIPQEERAM--------IFEPFFQGSHQrKGAVKGSGLGLSIARDCIRRMQGELYLVDESGQ 460
Cdd:cd16916 91 grgidrekirekaIERGLITADEAATLsddevlnlIFAPGFSTAEQ-VTDVSGRGVGMDVVKRSIESLGGTIEVESEPGQ 169
|
....*....
gi 90111458 461 DVCFRIELP 469
Cdd:cd16916 170 GTTFTIRLP 178
|
|
| COG3920 |
COG3920 |
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction ... |
290-469 |
1.63e-03 |
|
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms];
Pssm-ID: 443125 [Multi-domain] Cd Length: 495 Bit Score: 41.04 E-value: 1.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 290 VVSILDSSSRNLQ-KLIEQLLD--YNRKQADSAV--------ELENVELAPLVETVVSAHSLPARAKMMHTDVDL----- 353
Cdd:COG3920 313 VSSLLRLQARRADdPEAREALEesQNRIQALALVhellyqseDWEGVDLRDYLRELLEPLRDSYGGRGIRIELDGpdvel 392
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 354 ---KATAC---LAEpmllmsvldnLYSNAVHYGA---ESGNICLRSSLHGARVYIDVINTGTPIPQEeramiFEPffqgs 424
Cdd:COG3920 393 padAAVPLgliLNE----------LVTNALKHAFlsgEGGRIRVSWRREDGRLRLTVSDNGVGLPED-----VDP----- 452
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 90111458 425 hqrkgaVKGSGLGLSIARDCIRRMQGELYLVDESGqdVCFRIELP 469
Cdd:COG3920 453 ------PARKGLGLRLIRALVRQLGGTLELDRPEG--TRVRITFP 489
|
|
| HATPase_EL346-LOV-HK-like |
cd16951 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
339-467 |
4.63e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Erythrobacter litoralis blue light-activated histidine kinase 2; This domain family includes the histidine kinase-like ATPase (HATPase) domain of blue light-activated histidine kinase 2 of Erythrobacter litoralis (EL346). Signaling commonly occurs within HK dimers, however EL346 functions as a monomer. Also included in this family are the HATPase domains of ethanolamine utilization sensory transduction histidine kinase (EutW), whereby regulation of ethanolamine, a carbon and nitrogen source for gut bacteria, results in autophosphorylation and subsequent phosphoryl transfer to a response regulator (EutV) containing an RNA-binding domain. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory PAS sensor domain, while some have an N-terminal histidine kinase domain.
Pssm-ID: 340427 [Multi-domain] Cd Length: 131 Bit Score: 37.40 E-value: 4.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 339 SLPARAKMMHTDVDLKATACLAEPMLLMSVLDNLYSNAVHyGAESGNICLRSSLHGARVYIDVINTGTPIPQEeramiFE 418
Cdd:cd16951 18 VGDIRINITGDTGPVSSEVATAIGLVVNELLQNALKHAFS-DREGGTITIRSVVDGDYLRITVIDDGVGLPQD-----ED 91
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 90111458 419 PFFQGShqrkgavkgsgLGLSIARDCIRRMQGELYLVD--ESGQDVCFRIE 467
Cdd:cd16951 92 WPNKGS-----------LGLQIVRSLVEGELKAFLEVQsaENGTRVNIDIP 131
|
|
| HAMP |
pfam00672 |
HAMP domain; |
192-245 |
7.50e-03 |
|
HAMP domain;
Pssm-ID: 459898 [Multi-domain] Cd Length: 53 Bit Score: 34.52 E-value: 7.50e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 90111458 192 LFTRMIIGPVKNIERMINRLGEGRsLGNSVSFSGPSELRSVGQRILWLSERLSW 245
Cdd:pfam00672 1 LLARRILRPLRRLAEAARRIASGD-LDVRLPVSGRDEIGELARAFNQMAERLRE 53
|
|
| PRK11086 |
PRK11086 |
sensory histidine kinase DcuS; Provisional |
365-469 |
8.22e-03 |
|
sensory histidine kinase DcuS; Provisional
Pssm-ID: 236839 [Multi-domain] Cd Length: 542 Bit Score: 38.74 E-value: 8.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111458 365 LMSVLDNLYSNAVHY--GAESGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEpffQGsHQRKGavKGSGLGLSIAR 442
Cdd:PRK11086 434 LITILGNLIENALEAvgGEEGGEISVSLHYRNGWLHCEVSDDGPGIAPDEIDAIFD---KG-YSTKG--SNRGVGLYLVK 507
|
90 100
....*....|....*....|....*..
gi 90111458 443 DCIRRMQGELYLVDESGQDVCFRIELP 469
Cdd:PRK11086 508 QSVENLGGSIAVESEPGVGTQFFVQIP 534
|
|
| |
