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Conserved domains on  [gi|16130953|ref|NP_417529|]
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undecaprenyl pyrophosphate phosphatase [Escherichia coli str. K-12 substr. MG1655]

Protein Classification

undecaprenyl-diphosphate phosphatase( domain architecture ID 10011356)

undecaprenyl-diphosphate phosphatase catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) and confers resistance to bacitracin

EC:  3.6.1.27
Gene Ontology:  GO:0050380|GO:0005886
PubMed:  24068241

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK00281 PRK00281
undecaprenyl-diphosphate phosphatase;
3-273 2.63e-125

undecaprenyl-diphosphate phosphatase;


:

Pssm-ID: 234712  Cd Length: 268  Bit Score: 357.11  E-value: 2.63e-125
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130953    3 DMHSLLIAAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGDTAKTFEVVIQLGSILAVVVMFWRRLFGLIGIHFGRplqH 82
Cdd:PRK00281   1 DMMDLLKAIILGIVEGLTEFLPISSTGHLILVGHLLGFEDDFGKTFDVVIQLGAILAVVVYFRRRLWRLLGGSGKG---G 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130953   83 EGESKGRLTLIHILLGMIPAVVLGLLFHDTIKS-LFNPINVMYALVVGGLLLIAAECLKpkEPRAPGLDDMTYRQAFMIG 161
Cdd:PRK00281  78 RGDREDRRLLLLVIVATIPAGVLGLLFKDFIKEhLFSPIVVAIALIVGGILLLWAEKRK--GPRVRSLDDLTYKDALLIG 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130953  162 CFQCLALWPGFSRSGATISGGMLMGVSRYAASEFSFLLAVPMMMGATALDLYKSWGFLTSGDIPMFAVGFITAFVVALIA 241
Cdd:PRK00281 156 LAQCLALIPGTSRSGATISGGLLLGLSREAAAEFSFLLAIPAMLGASLLDLLKLFHLLSAADLPLLAVGFVVAFVVALIA 235
                        250       260       270
                 ....*....|....*....|....*....|..
gi 16130953  242 IKTFLQLIKRISFIPFAIYRFIVAAAVYVVFF 273
Cdd:PRK00281 236 IKWLLKYIKRHSFTPFAIYRIILGALLLILLF 267
 
Name Accession Description Interval E-value
PRK00281 PRK00281
undecaprenyl-diphosphate phosphatase;
3-273 2.63e-125

undecaprenyl-diphosphate phosphatase;


Pssm-ID: 234712  Cd Length: 268  Bit Score: 357.11  E-value: 2.63e-125
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130953    3 DMHSLLIAAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGDTAKTFEVVIQLGSILAVVVMFWRRLFGLIGIHFGRplqH 82
Cdd:PRK00281   1 DMMDLLKAIILGIVEGLTEFLPISSTGHLILVGHLLGFEDDFGKTFDVVIQLGAILAVVVYFRRRLWRLLGGSGKG---G 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130953   83 EGESKGRLTLIHILLGMIPAVVLGLLFHDTIKS-LFNPINVMYALVVGGLLLIAAECLKpkEPRAPGLDDMTYRQAFMIG 161
Cdd:PRK00281  78 RGDREDRRLLLLVIVATIPAGVLGLLFKDFIKEhLFSPIVVAIALIVGGILLLWAEKRK--GPRVRSLDDLTYKDALLIG 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130953  162 CFQCLALWPGFSRSGATISGGMLMGVSRYAASEFSFLLAVPMMMGATALDLYKSWGFLTSGDIPMFAVGFITAFVVALIA 241
Cdd:PRK00281 156 LAQCLALIPGTSRSGATISGGLLLGLSREAAAEFSFLLAIPAMLGASLLDLLKLFHLLSAADLPLLAVGFVVAFVVALIA 235
                        250       260       270
                 ....*....|....*....|....*....|..
gi 16130953  242 IKTFLQLIKRISFIPFAIYRFIVAAAVYVVFF 273
Cdd:PRK00281 236 IKWLLKYIKRHSFTPFAIYRIILGALLLILLF 267
UppP COG1968
Undecaprenyl pyrophosphate phosphatase [Lipid transport and metabolism];
6-273 5.23e-113

Undecaprenyl pyrophosphate phosphatase [Lipid transport and metabolism];


Pssm-ID: 441571  Cd Length: 265  Bit Score: 325.84  E-value: 5.23e-113
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130953   6 SLLIAAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGDTAKTFEVVIQLGSILAVVVMFWRRLFGLIGIHFGRPLQHEGE 85
Cdd:COG1968   2 DLLQAIILGIVQGLTEFLPVSSSGHLILVPALLGWEGDPGLAFDVVIQLGTLLAVLVYFRKDILRLLRGLFRSLRRDDPD 81
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130953  86 SKgrlTLIHILLGMIPAVVLGLLFHDTIKS-LFNPINVMYALVVGGLLLIAAECLKPKEPRapgLDDMTYRQAFMIGCFQ 164
Cdd:COG1968  82 AR---LALLIIVATIPAAIIGLLFKDFIESlLRSPLVVAIALIVGGLLLLLAERLGRRKRT---LEDLTLKDALLIGLAQ 155
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130953 165 CLALWPGFSRSGATISGGMLMGVSRYAASEFSFLLAVPMMMGATALDLYKSWGFLTSGDIPMFAVGFITAFVVALIAIKT 244
Cdd:COG1968 156 ALALIPGVSRSGATITGGLLLGLSREAAARFSFLLAIPAILGAGLLELLKLLKALSSVDLGPLLVGFVVAFVVAYLAIKW 235
                       250       260
                ....*....|....*....|....*....
gi 16130953 245 FLQLIKRISFIPFAIYRFIVAAAVYVVFF 273
Cdd:COG1968 236 LLRYLKRHSFKPFAIYRIILGIVLLILLL 264
undec_PP_bacA TIGR00753
undecaprenyl-diphosphatase UppP; This is a family of small, highly hydrophobic proteins. ...
10-265 1.07e-110

undecaprenyl-diphosphatase UppP; This is a family of small, highly hydrophobic proteins. Overexpression of this protein in Escherichia coli is associated with bacitracin resistance, and the protein was originally proposed to be an undecaprenol kinase and called bacA. It is now known to be an undecaprenyl pyrophosphate phosphatase (EC 3.6.1.27) and is renamed UppP. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]


Pssm-ID: 129836  Cd Length: 255  Bit Score: 319.72  E-value: 1.07e-110
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130953    10 AAILGVVEGLTEFLPVSSTGHMIIVGHLLGfEGDTAKTFEVVIQLGSILAVVVMFWRRLFGLIGIHFGRpLQHEGESKGR 89
Cdd:TIGR00753   1 AIILGIVQGLTEFLPISSTGHLIIVRHILG-SGDAGKSFTIVIQLGSILAVVIYFWRRILRLLGIWIRF-STRKTESSDL 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130953    90 LTLIHILLGMIPAVVLGLLFHDTIKSLF--NPINVMYALVVGGLLLIAAECLKpKEPRAPGLDDMTYRQAFMIGCFQCLA 167
Cdd:TIGR00753  79 LLLKLILLGLIPTVVLGLLFKDLIKSLLfnFLLTVVIALIVGAGLLILAEEVN-RQTLKRDFERLTLRDAIMMGLFQCLA 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130953   168 LWPGFSRSGATISGGMLMGVSRYAASEFSFLLAVPMMMGATALDLYKSWGFLTSGDIPMFAVGFITAFVVALIAIKTFLQ 247
Cdd:TIGR00753 158 LIPGVSRSGSTISGGLFIGLNRKAAAEFSFLLAIPIMFGAGLLSLKKSWDSFTSGDFPELIVGFITAFVVALFAIAWFLK 237
                         250
                  ....*....|....*...
gi 16130953   248 LIKRISFIPFAIYRFIVA 265
Cdd:TIGR00753 238 FLNKHSLYIFVIYRFILG 255
BacA pfam02673
Bacitracin resistance protein BacA; Bacitracin resistance protein (BacA) is a putative ...
10-267 2.58e-102

Bacitracin resistance protein BacA; Bacitracin resistance protein (BacA) is a putative undecaprenol kinase. BacA confers resistance to bacitracin, probably by phosphorylation of undecaprenol. More recent studies show that BacA has undecaprenyl pyrophosphate phosphatase activity. Undecaprenyl phosphate is a key lipid intermediate involved in the synthesis of various bacterial cell wall polymers. Bacitracin, a mixture of related cyclic polypeptide antibiotics, is used to treat surface tissue infections. Its primary mode of action is the inhibition of bacterial cell wall synthesis through sequestration of the essential carrier lipid undecaprenyl pyrophosphate, C55-PP, resulting in the loss of cell integrity and lysis. The characteriztic phosphatase sequence-motif in this family is likely to be the PGxSRSGG, compared with the PSGH of the PAP family of phosphatases.


Pssm-ID: 460646  Cd Length: 259  Bit Score: 298.60  E-value: 2.58e-102
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130953    10 AAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGDT--AKTFEVVIQLGSILAVVVMFWRRLFGLIGIHFGRPLQHEGESK 87
Cdd:pfam02673   1 AIILGIVQGLTEFLPVSSSGHLILVPHLLGFGWEDpgLAAFDVVIHLGTILAVLVYFRKDIWRLLKGFFRSLKKRFADDP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130953    88 GRLTLIHILLGMIPAVVLGLLFHDTIKSLF-NPINVMYALVVGGLLLIAAECLKPKEPRapGLDDMTYRQAFMIGCFQCL 166
Cdd:pfam02673  81 DRRLAWLIIVATIPAGILGLLLKDFIEALLrSPLVVAIALIVTGLLLLLAERLGKRKRK--SLDDLTLKDALIIGLAQAL 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130953   167 ALWPGFSRSGATISGGMLMGVSRYAASEFSFLLAVPMMMGATALDLYKSWGFLTSGDIPMFAVGFITAFVVALIAIKTFL 246
Cdd:pfam02673 159 ALIPGVSRSGATITGGLLLGLSREAAARFSFLLAIPAILGAGLLELLLKSGSGLLTGDLALLVGFVVAFVVGYLAIKFLL 238
                         250       260
                  ....*....|....*....|.
gi 16130953   247 QLIKRISFIPFAIYRFIVAAA 267
Cdd:pfam02673 239 RYVKKHSLKPFAIYRIILGIL 259
 
Name Accession Description Interval E-value
PRK00281 PRK00281
undecaprenyl-diphosphate phosphatase;
3-273 2.63e-125

undecaprenyl-diphosphate phosphatase;


Pssm-ID: 234712  Cd Length: 268  Bit Score: 357.11  E-value: 2.63e-125
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130953    3 DMHSLLIAAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGDTAKTFEVVIQLGSILAVVVMFWRRLFGLIGIHFGRplqH 82
Cdd:PRK00281   1 DMMDLLKAIILGIVEGLTEFLPISSTGHLILVGHLLGFEDDFGKTFDVVIQLGAILAVVVYFRRRLWRLLGGSGKG---G 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130953   83 EGESKGRLTLIHILLGMIPAVVLGLLFHDTIKS-LFNPINVMYALVVGGLLLIAAECLKpkEPRAPGLDDMTYRQAFMIG 161
Cdd:PRK00281  78 RGDREDRRLLLLVIVATIPAGVLGLLFKDFIKEhLFSPIVVAIALIVGGILLLWAEKRK--GPRVRSLDDLTYKDALLIG 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130953  162 CFQCLALWPGFSRSGATISGGMLMGVSRYAASEFSFLLAVPMMMGATALDLYKSWGFLTSGDIPMFAVGFITAFVVALIA 241
Cdd:PRK00281 156 LAQCLALIPGTSRSGATISGGLLLGLSREAAAEFSFLLAIPAMLGASLLDLLKLFHLLSAADLPLLAVGFVVAFVVALIA 235
                        250       260       270
                 ....*....|....*....|....*....|..
gi 16130953  242 IKTFLQLIKRISFIPFAIYRFIVAAAVYVVFF 273
Cdd:PRK00281 236 IKWLLKYIKRHSFTPFAIYRIILGALLLILLF 267
UppP COG1968
Undecaprenyl pyrophosphate phosphatase [Lipid transport and metabolism];
6-273 5.23e-113

Undecaprenyl pyrophosphate phosphatase [Lipid transport and metabolism];


Pssm-ID: 441571  Cd Length: 265  Bit Score: 325.84  E-value: 5.23e-113
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130953   6 SLLIAAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGDTAKTFEVVIQLGSILAVVVMFWRRLFGLIGIHFGRPLQHEGE 85
Cdd:COG1968   2 DLLQAIILGIVQGLTEFLPVSSSGHLILVPALLGWEGDPGLAFDVVIQLGTLLAVLVYFRKDILRLLRGLFRSLRRDDPD 81
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130953  86 SKgrlTLIHILLGMIPAVVLGLLFHDTIKS-LFNPINVMYALVVGGLLLIAAECLKPKEPRapgLDDMTYRQAFMIGCFQ 164
Cdd:COG1968  82 AR---LALLIIVATIPAAIIGLLFKDFIESlLRSPLVVAIALIVGGLLLLLAERLGRRKRT---LEDLTLKDALLIGLAQ 155
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130953 165 CLALWPGFSRSGATISGGMLMGVSRYAASEFSFLLAVPMMMGATALDLYKSWGFLTSGDIPMFAVGFITAFVVALIAIKT 244
Cdd:COG1968 156 ALALIPGVSRSGATITGGLLLGLSREAAARFSFLLAIPAILGAGLLELLKLLKALSSVDLGPLLVGFVVAFVVAYLAIKW 235
                       250       260
                ....*....|....*....|....*....
gi 16130953 245 FLQLIKRISFIPFAIYRFIVAAAVYVVFF 273
Cdd:COG1968 236 LLRYLKRHSFKPFAIYRIILGIVLLILLL 264
undec_PP_bacA TIGR00753
undecaprenyl-diphosphatase UppP; This is a family of small, highly hydrophobic proteins. ...
10-265 1.07e-110

undecaprenyl-diphosphatase UppP; This is a family of small, highly hydrophobic proteins. Overexpression of this protein in Escherichia coli is associated with bacitracin resistance, and the protein was originally proposed to be an undecaprenol kinase and called bacA. It is now known to be an undecaprenyl pyrophosphate phosphatase (EC 3.6.1.27) and is renamed UppP. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]


Pssm-ID: 129836  Cd Length: 255  Bit Score: 319.72  E-value: 1.07e-110
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130953    10 AAILGVVEGLTEFLPVSSTGHMIIVGHLLGfEGDTAKTFEVVIQLGSILAVVVMFWRRLFGLIGIHFGRpLQHEGESKGR 89
Cdd:TIGR00753   1 AIILGIVQGLTEFLPISSTGHLIIVRHILG-SGDAGKSFTIVIQLGSILAVVIYFWRRILRLLGIWIRF-STRKTESSDL 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130953    90 LTLIHILLGMIPAVVLGLLFHDTIKSLF--NPINVMYALVVGGLLLIAAECLKpKEPRAPGLDDMTYRQAFMIGCFQCLA 167
Cdd:TIGR00753  79 LLLKLILLGLIPTVVLGLLFKDLIKSLLfnFLLTVVIALIVGAGLLILAEEVN-RQTLKRDFERLTLRDAIMMGLFQCLA 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130953   168 LWPGFSRSGATISGGMLMGVSRYAASEFSFLLAVPMMMGATALDLYKSWGFLTSGDIPMFAVGFITAFVVALIAIKTFLQ 247
Cdd:TIGR00753 158 LIPGVSRSGSTISGGLFIGLNRKAAAEFSFLLAIPIMFGAGLLSLKKSWDSFTSGDFPELIVGFITAFVVALFAIAWFLK 237
                         250
                  ....*....|....*...
gi 16130953   248 LIKRISFIPFAIYRFIVA 265
Cdd:TIGR00753 238 FLNKHSLYIFVIYRFILG 255
BacA pfam02673
Bacitracin resistance protein BacA; Bacitracin resistance protein (BacA) is a putative ...
10-267 2.58e-102

Bacitracin resistance protein BacA; Bacitracin resistance protein (BacA) is a putative undecaprenol kinase. BacA confers resistance to bacitracin, probably by phosphorylation of undecaprenol. More recent studies show that BacA has undecaprenyl pyrophosphate phosphatase activity. Undecaprenyl phosphate is a key lipid intermediate involved in the synthesis of various bacterial cell wall polymers. Bacitracin, a mixture of related cyclic polypeptide antibiotics, is used to treat surface tissue infections. Its primary mode of action is the inhibition of bacterial cell wall synthesis through sequestration of the essential carrier lipid undecaprenyl pyrophosphate, C55-PP, resulting in the loss of cell integrity and lysis. The characteriztic phosphatase sequence-motif in this family is likely to be the PGxSRSGG, compared with the PSGH of the PAP family of phosphatases.


Pssm-ID: 460646  Cd Length: 259  Bit Score: 298.60  E-value: 2.58e-102
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130953    10 AAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGDT--AKTFEVVIQLGSILAVVVMFWRRLFGLIGIHFGRPLQHEGESK 87
Cdd:pfam02673   1 AIILGIVQGLTEFLPVSSSGHLILVPHLLGFGWEDpgLAAFDVVIHLGTILAVLVYFRKDIWRLLKGFFRSLKKRFADDP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130953    88 GRLTLIHILLGMIPAVVLGLLFHDTIKSLF-NPINVMYALVVGGLLLIAAECLKPKEPRapGLDDMTYRQAFMIGCFQCL 166
Cdd:pfam02673  81 DRRLAWLIIVATIPAGILGLLLKDFIEALLrSPLVVAIALIVTGLLLLLAERLGKRKRK--SLDDLTLKDALIIGLAQAL 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130953   167 ALWPGFSRSGATISGGMLMGVSRYAASEFSFLLAVPMMMGATALDLYKSWGFLTSGDIPMFAVGFITAFVVALIAIKTFL 246
Cdd:pfam02673 159 ALIPGVSRSGATITGGLLLGLSREAAARFSFLLAIPAILGAGLLELLLKSGSGLLTGDLALLVGFVVAFVVGYLAIKFLL 238
                         250       260
                  ....*....|....*....|.
gi 16130953   247 QLIKRISFIPFAIYRFIVAAA 267
Cdd:pfam02673 239 RYVKKHSLKPFAIYRIILGIL 259
PRK12554 PRK12554
undecaprenyl pyrophosphate phosphatase; Reviewed
6-273 4.10e-87

undecaprenyl pyrophosphate phosphatase; Reviewed


Pssm-ID: 237134  Cd Length: 276  Bit Score: 260.52  E-value: 4.10e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130953    6 SLLIAAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGDTAkTFEVVIQLGSILAVVVMFWRRLFGLIGIHFGRPLQHEGE 85
Cdd:PRK12554   2 SLFKAIILGLVQGLTEFLPVSSSGHLRIVGALLGWDDPGA-AFTAIIQLGTLLAVLLYFRKDIIRIIKNFFSSLFGRKPK 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130953   86 SKGRLTL-IHILLGMIPAVVLGLLFHDTIK-SLFNPINVMYALVVGGLLLIAAECLKPKEPRAPgLDDMTYRQAFMIGCF 163
Cdd:PRK12554  81 AKSDARFgWYIIIGTIPAGVLGLLFKDRIEtVLRDLRIVAIALIVTGVLLWLADNLARNRGRKS-DEDLTWKDAIIIGLA 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130953  164 QCLALWPGFSRSGATISGGMLMGVSRYAASEFSFLLAVPMMMGATALDLYKSWGFL-TSGDIPMFAVGFITAFVVALIAI 242
Cdd:PRK12554 160 QALALIPGVSRSGATIIAGLLLGLTREAAARFSFLLAIPAVFGAGLLELYKIFHDPnASTLLGPTAVAFIVAFIVGYISI 239
                        250       260       270
                 ....*....|....*....|....*....|.
gi 16130953  243 KTFLQLIKRISFIPFAIYRFIVAAAVYVVFF 273
Cdd:PRK12554 240 AWFMNFLKKGSLKYFAIYRIILGVLLLILLG 270
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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