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Conserved domains on  [gi|16130966|ref|NP_417542|]
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DNA-binding transcriptional repressor NfeR [Escherichia coli str. K-12 substr. MG1655]

Protein Classification

PadR family transcriptional regulator( domain architecture ID 11447737)

PadR family transcriptional regulator similar to the phenolic acid decarboxylation repressor, which is a transcription factor that represses genes associated with the phenolic acid stress response in gram-positive bacteria

Gene Ontology:  GO:0003677|GO:0003700
PubMed:  10679470|10908318|10473770|15808743|8831795

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PadR COG1695
DNA-binding transcriptional regulator, PadR family [Transcription];
60-151 1.37e-24

DNA-binding transcriptional regulator, PadR family [Transcription];


:

Pssm-ID: 441301  Cd Length: 102  Bit Score: 92.69  E-value: 1.37e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130966  60 HGELRLVILDILSRDDSHGYELIKAIENLTQGNYTPSPGVIYPTLDFLQEQSLITIREEEGG----KKQIALTEQGAQWL 135
Cdd:COG1695   7 KGTLELLILALLAEGPMYGYEIIKELEERSGGFWKVSEGTLYPALKRLEKEGLVESEWEESEggprRKYYRLTEAGREEL 86

                        90
                ....*....|....*.
gi 16130966 136 EENREQVEMIEERIKA 151
Cdd:COG1695  87 AEWLEEWEKLAEALEA 102
 
Name Accession Description Interval E-value
PadR COG1695
DNA-binding transcriptional regulator, PadR family [Transcription];
60-151 1.37e-24

DNA-binding transcriptional regulator, PadR family [Transcription];


Pssm-ID: 441301  Cd Length: 102  Bit Score: 92.69  E-value: 1.37e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130966  60 HGELRLVILDILSRDDSHGYELIKAIENLTQGNYTPSPGVIYPTLDFLQEQSLITIREEEGG----KKQIALTEQGAQWL 135
Cdd:COG1695   7 KGTLELLILALLAEGPMYGYEIIKELEERSGGFWKVSEGTLYPALKRLEKEGLVESEWEESEggprRKYYRLTEAGREEL 86

                        90
                ....*....|....*.
gi 16130966 136 EENREQVEMIEERIKA 151
Cdd:COG1695  87 AEWLEEWEKLAEALEA 102
PadR pfam03551
Transcriptional regulator PadR-like family; Members of this family are transcriptional ...
 67-136 1.36e-16

Transcriptional regulator PadR-like family; Members of this family are transcriptional regulators that appear to be related to the pfam01047 family. This family includes PadR, a protein that is involved in negative regulation of phenolic acid metabolism.


Pssm-ID: 397561  Cd Length: 74  Bit Score: 71.12  E-value: 1.36e-16
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 16130966    67 ILDILSRDDSHGYELIKAIENLTQGNYTPSPGVIYPTLDFLQEQSLITIREEEGG----KKQIALTEQGAQWLE 136
Cdd:pfam03551   1 VLAVLGEQPRYGYEIIKELEELSGGFWRPSEGTLYPILKRLEKEGLVESEWVDSGggppRKYYRLTDAGRRELA 74
 
Name Accession Description Interval E-value
PadR COG1695
DNA-binding transcriptional regulator, PadR family [Transcription];
60-151 1.37e-24

DNA-binding transcriptional regulator, PadR family [Transcription];


Pssm-ID: 441301  Cd Length: 102  Bit Score: 92.69  E-value: 1.37e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130966  60 HGELRLVILDILSRDDSHGYELIKAIENLTQGNYTPSPGVIYPTLDFLQEQSLITIREEEGG----KKQIALTEQGAQWL 135
Cdd:COG1695   7 KGTLELLILALLAEGPMYGYEIIKELEERSGGFWKVSEGTLYPALKRLEKEGLVESEWEESEggprRKYYRLTEAGREEL 86

                        90
                ....*....|....*.
gi 16130966 136 EENREQVEMIEERIKA 151
Cdd:COG1695  87 AEWLEEWEKLAEALEA 102
PadR pfam03551
Transcriptional regulator PadR-like family; Members of this family are transcriptional ...
 67-136 1.36e-16

Transcriptional regulator PadR-like family; Members of this family are transcriptional regulators that appear to be related to the pfam01047 family. This family includes PadR, a protein that is involved in negative regulation of phenolic acid metabolism.


Pssm-ID: 397561  Cd Length: 74  Bit Score: 71.12  E-value: 1.36e-16
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 16130966    67 ILDILSRDDSHGYELIKAIENLTQGNYTPSPGVIYPTLDFLQEQSLITIREEEGG----KKQIALTEQGAQWLE 136
Cdd:pfam03551   1 VLAVLGEQPRYGYEIIKELEELSGGFWRPSEGTLYPILKRLEKEGLVESEWVDSGggppRKYYRLTDAGRRELA 74
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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