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Conserved domains on  [gi|90111569|ref|NP_417784|]
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Type II secretion system protein GspD [Escherichia coli str. K-12 substr. MG1655]

Protein Classification

type II secretion system protein D( domain architecture ID 11494410)

type II secretion system protein D is involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins

CATH:  3.30.1370.120|3.55.50.30
Gene Ontology:  GO:0009279|GO:0015627|GO:0015628
PubMed:  30767847
TCDB:  1.B.22.1.3

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
type_II_gspD TIGR02517
type II secretion system protein D; In Gram-negative bacteria, proteins that have first ...
 30-604 0e+00

type II secretion system protein D; In Gram-negative bacteria, proteins that have first crossed the inner member by Sec-dependent protein transport can be exported across the outer membrane by type II secretion, also called the main terminal branch of the general secretion pathway. Members of this family are general secretion pathway protein D. In Yersinia enterocolitica, a second member of this family is part of a novel second type II secretion system specifically associated with virulence (See ). This family is closely homologous to the type IV pilus outer membrane secretin PilQ (TIGR02515) and to the type III secretion system pore YscC/HrcC (TIGR02516). [Protein fate, Protein and peptide secretion and trafficking]


:

Pssm-ID: 274175 [Multi-domain]  Cd Length: 594  Bit Score: 678.34  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569    30 ANFNNADIRQFVEIVGQHLGKTILIDPSVQGTISVRSNDTFSQQEYYQFFLSILDLYGYSVITLDNGFLKVVRSANVKTS 109
Cdd:TIGR02517   1 LNFVDADISTVVKAISDLTGKNFIIDPRVKGKITIISPRPVTEDEAYQLFLSALRAQGFAVVPEGNGYKIVVPRAAAKLS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569   110 PGMIADSSRPGVG-DELVTRIVPLENVPARDLAPLLRQMMDAgsVGNVVHYEPSNVLILTGRASTINKLIEVIKRVDVIG 188
Cdd:TIGR02517  81 PGPIEDGPAPGVGgDQFVTRVFPLRNISASELVPVLRPLVSP--NGDVAAYPPTNTIVVTDYASNINRVARIIQQLDVDG 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569   189 TEKQQIIHLEYASAEDLAEILNQLISEshGKSQMPALLSAKIVADKRTNSLIISGPEKARQRITSLLKSLDVEESEEGNT 268
Cdd:TIGR02517 159 AGSVEVIPLKNASAVDIADVLNKLLGE--GGKTDGGGKLSVIAPDRRNNILIRAGSPEALERIKKLISQLDVPASEGGNV 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569   269 RVYYLKYAKATNLVEVLTGVSEKLKDEKGNARKPSSSGAMDN----------------VAITADEQTNSLVITADQSVQE 332
Cdd:TIGR02517 237 RVYYLRNADAEELAKTLQGVFGGGGNEPGSSSSPGLGGAVNPggsqsaqaassasggsVSGSADKATNSLIITASPQDYK 316

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569   333 KLATVIARLDIRRAQVLVEAIIVEVQDGNGLNLGVQWANKNVGAQQFTNTGLPIFNAAQGVADYKKNGGITSANPAWDMF 412
Cdd:TIGR02517 317 NIRAVIKQLDVRRAQVLVEAIIVEVSLDDALELGVQWLIAGTGGGVNFSTGSPNSGSLLGASASAISLGSAGIGLLVTSS 396

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569   413 SAYNGMAAGFFNGDWGVLLTALASNNKNDILATPSIVTLDNKLASFNVGQDVPVLSGSQ----TTSGDNVFNTVERKTVG 488
Cdd:TIGR02517 397 STTSGVGGTGGGPNLGVLLNALKQDTGFNVLSTPSLLTLDNQEAEINVGQEVPVLTGSYntgtGGTNANPFNTYQRKDVG 476

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569   489 TKLKVTPQVNEGDAVLLEIEQEVS--SVDSSSNSTLGPTFNTRTIQNAVLVKTGETVVLGGLLDDFSKEQVSKVPLLGDI 566
Cdd:TIGR02517 477 IKLKVTPQINEGGTVRLEIYQEVSsvAPTTVGSAASGPTFNKREIKTVVLVDNGDTVVLGGLIQDKTSESVTKVPLLGDI 556

                         570       580       590
                  ....*....|....*....|....*....|....*...
gi 90111569   567 PLVGQLFRYTSTERAKRNLMVFIRPTIIRDDDVYRSLS 604
Cdd:TIGR02517 557 PVLGWLFRSTTTERTKTNLMVFITPRIIRDPEDARALT 594
 
Name Accession Description Interval E-value
type_II_gspD TIGR02517
type II secretion system protein D; In Gram-negative bacteria, proteins that have first ...
 30-604 0e+00

type II secretion system protein D; In Gram-negative bacteria, proteins that have first crossed the inner member by Sec-dependent protein transport can be exported across the outer membrane by type II secretion, also called the main terminal branch of the general secretion pathway. Members of this family are general secretion pathway protein D. In Yersinia enterocolitica, a second member of this family is part of a novel second type II secretion system specifically associated with virulence (See ). This family is closely homologous to the type IV pilus outer membrane secretin PilQ (TIGR02515) and to the type III secretion system pore YscC/HrcC (TIGR02516). [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274175 [Multi-domain]  Cd Length: 594  Bit Score: 678.34  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569    30 ANFNNADIRQFVEIVGQHLGKTILIDPSVQGTISVRSNDTFSQQEYYQFFLSILDLYGYSVITLDNGFLKVVRSANVKTS 109
Cdd:TIGR02517   1 LNFVDADISTVVKAISDLTGKNFIIDPRVKGKITIISPRPVTEDEAYQLFLSALRAQGFAVVPEGNGYKIVVPRAAAKLS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569   110 PGMIADSSRPGVG-DELVTRIVPLENVPARDLAPLLRQMMDAgsVGNVVHYEPSNVLILTGRASTINKLIEVIKRVDVIG 188
Cdd:TIGR02517  81 PGPIEDGPAPGVGgDQFVTRVFPLRNISASELVPVLRPLVSP--NGDVAAYPPTNTIVVTDYASNINRVARIIQQLDVDG 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569   189 TEKQQIIHLEYASAEDLAEILNQLISEshGKSQMPALLSAKIVADKRTNSLIISGPEKARQRITSLLKSLDVEESEEGNT 268
Cdd:TIGR02517 159 AGSVEVIPLKNASAVDIADVLNKLLGE--GGKTDGGGKLSVIAPDRRNNILIRAGSPEALERIKKLISQLDVPASEGGNV 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569   269 RVYYLKYAKATNLVEVLTGVSEKLKDEKGNARKPSSSGAMDN----------------VAITADEQTNSLVITADQSVQE 332
Cdd:TIGR02517 237 RVYYLRNADAEELAKTLQGVFGGGGNEPGSSSSPGLGGAVNPggsqsaqaassasggsVSGSADKATNSLIITASPQDYK 316

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569   333 KLATVIARLDIRRAQVLVEAIIVEVQDGNGLNLGVQWANKNVGAQQFTNTGLPIFNAAQGVADYKKNGGITSANPAWDMF 412
Cdd:TIGR02517 317 NIRAVIKQLDVRRAQVLVEAIIVEVSLDDALELGVQWLIAGTGGGVNFSTGSPNSGSLLGASASAISLGSAGIGLLVTSS 396

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569   413 SAYNGMAAGFFNGDWGVLLTALASNNKNDILATPSIVTLDNKLASFNVGQDVPVLSGSQ----TTSGDNVFNTVERKTVG 488
Cdd:TIGR02517 397 STTSGVGGTGGGPNLGVLLNALKQDTGFNVLSTPSLLTLDNQEAEINVGQEVPVLTGSYntgtGGTNANPFNTYQRKDVG 476

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569   489 TKLKVTPQVNEGDAVLLEIEQEVS--SVDSSSNSTLGPTFNTRTIQNAVLVKTGETVVLGGLLDDFSKEQVSKVPLLGDI 566
Cdd:TIGR02517 477 IKLKVTPQINEGGTVRLEIYQEVSsvAPTTVGSAASGPTFNKREIKTVVLVDNGDTVVLGGLIQDKTSESVTKVPLLGDI 556

                         570       580       590
                  ....*....|....*....|....*....|....*...
gi 90111569   567 PLVGQLFRYTSTERAKRNLMVFIRPTIIRDDDVYRSLS 604
Cdd:TIGR02517 557 PVLGWLFRSTTTERTKTNLMVFITPRIIRDPEDARALT 594
PulD COG1450
Type II secretory pathway component GspD/PulD (secretin) [Intracellular trafficking, secretion, ...
 275-615 3.18e-97

Type II secretory pathway component GspD/PulD (secretin) [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 441059 [Multi-domain]  Cd Length: 333  Bit Score: 301.46  E-value: 3.18e-97
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569 275 YAKATNLVEVLTGVSeklkdekgnarkpsssGAMDNVAITADEQTNSLVITADQSVQEKLATVIARLDIRRAQVLVEAII 354
Cdd:COG1450  24 YADAEDLAKVLRSLL----------------GGAAGVSVVADPRTNSLIVRATPEQLREIEELIEQLDVPRRQVLIEAKI 87

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569 355 VEVQDGNGLNLGVQWA--NKNVGAQQFTNTGLPIFNAAQGvadykknggitsanpawdmfSAYNGMAAGFFN-GDWGVLL 431
Cdd:COG1450  88 VEVSLSDLRELGIDWSalGGNGGGVNFGGTGSLGSLAAAG--------------------SLGGGLNLGLLGgGNFGALL 147

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569 432 TALASNNKNDILATPSIVTLDNKLASFNVGQDVPVLSGSQTTSG-DNVFNTVERKTVGTKLKVTPQVNEGDAVLLEIEQE 510
Cdd:COG1450 148 NALESNGDANVLSSPSILTLNNQEAVIKVGQTVPYVTGSTTTSStGNPTTTIEYVDVGITLKVTPQINEDGTVTLDINPE 227

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569 511 V--SSVDSSSNSTLGPTFNTRTIQNAVLVKTGETVVLGGLLDDFSKEQVSKVPLLGDIPLVGQLFRYTSTERAKRNLMVF 588
Cdd:COG1450 228 VssVTGSTTGGGNGLPTINKREISTTVRVKDGQTVVLGGLIRDEESESESKVPLLGDIPLLGRLFRSTSKSKEKTELVIF 307

                       330       340
                ....*....|....*....|....*..
gi 90111569 589 IRPTIIRDDDVYRSLSKEkYTRYRQEQ 615
Cdd:COG1450 308 ITPTIIRDGEDAQALTEE-YDRLRALQ 333
Secretin pfam00263
Bacterial type II and III secretion system protein;
433-594 3.42e-52

Bacterial type II and III secretion system protein;


Pssm-ID: 459738 [Multi-domain]  Cd Length: 159  Bit Score: 176.94  E-value: 3.42e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569   433 ALASNNKNDILATPSIVTLDNKLASFNVGQDVPVLSGSQTTSGDNVfnTVERKTVGTKLKVTPQVNEGDAVLLEIEQEVS 512
Cdd:pfam00263   1 ALEQNGKAKILSSPSLLTLDNQEASIKVGQEVPVPTTSTTGGTTTT--TVEFKDAGLSLKVTPQVTPDGTITLKINPEVS 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569   513 SVDSSSNSTlGPTFNTRTIQNAVLVKTGETVVLGGLLDDFSKEQVSKVPLLGDIPLVGQLFRYTSTERAKRNLMVFIRPT 592
Cdd:pfam00263  79 SPDGNGGNG-VPTINTREISTTVRVKDGQTVVIGGLIQEEDSETESKVPLLGDIPLLGALFRSTSKSKEKTELLIFITPR 157


                  ..
gi 90111569   593 II 594
Cdd:pfam00263 158 IV 159
IV PHA00019
phage assembly protein
 11-595 1.06e-50

phage assembly protein


Pssm-ID: 222772 [Multi-domain]  Cd Length: 428  Bit Score: 181.55  E-value: 1.06e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569   11 LLAALLMPCAGHAENEQYgaNFNNADIRQFVEIVGQHLGKTILIDPSVQGTISVRSNDtFSQQEYYQFFLSILDlygysv 90
Cdd:PHA00019   9 MLLFLLMFLSFSSFALPV--ELNNSPIREFVSWYSQQTGKSVVLGPDVKGNVTVYSAD-VNPANLPQFFDSVLR------ 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569   91 itlDNGFLKVvrsanvktspgmiadssrpGVGDELVTRIVPLENVPARDLAPLLRQMMDAGSVgNVVHYEPSNVLILtgr 170
Cdd:PHA00019  80 ---ANGFDLV-------------------AGGPAVVIKQNPNQEDYADDLRDSRDDVFYDNSV-PSGAPEVPNDLIV--- 133

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569  171 astinklievikrvdvigtekqQIIHLEYASAEDLAEIlnqliseshgksqmpallsakivadkrtnsliisgpekarqr 250
Cdd:PHA00019 134 ----------------------RTFNINNVRASDLLPL------------------------------------------ 149

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569  251 ITSLLKSLDVeeseegntrvyylkyakatnlvevltgvseklkdekgnarkpsssgamDNVAITADEQTNSLVITADQSV 330
Cdd:PHA00019 150 VKIFVKSNGA------------------------------------------------PGGSVTDLPGTNSLVVSGSASQ 181

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569  331 QEKLATVIARLDIRRAQVLVEAIIVEVQDGNGLNLGVQWANKNVGAQQftntglpifnaaqgvadykknGGITSANPAWD 410
Cdd:PHA00019 182 LPALADFISAIDVPRRQVLIEALIFETSLGDGVDLSFAAGLASGGKVA---------------------GGFNTARLTTV 240

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569  411 MFSAynGMAAGFFNGD-WGVLLTALASNNKNDILATPSIVTLDNKLASFNVGQDVPVLSGSQT---TSGDNVFNTVERKT 486
Cdd:PHA00019 241 LSSA--GGSFGIFNGNvLGLSVKALENSSNSRVLSRPRILTLSGQSGYISVGQNVPFVTGRVTgeaANVNNPFQTIERKD 318

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569  487 VGTKLKVTPQVNEGDAVLLEIEQEVSSVDSSSNSTLGPTfNTRTIQNAVLVKTGETVVLGGLLDDFSKEQVSKVPLLGDI 566
Cdd:PHA00019 319 VGVSLEVTPVVMGDGQLVLDIDTKADSLSDSTIASDIIT-NQRSLQTTVQVKDGQTLLLGGLISSNNTDGDSSVPFLSKI 397

                        570       580
                 ....*....|....*....|....*....
gi 90111569  567 PLVGQLFRYTSTERAKRNLMVFIRPTIIR 595
Cdd:PHA00019 398 PLIGWLFRSKSDSNEQRTLYVLLTARVIK 426
 
Name Accession Description Interval E-value
type_II_gspD TIGR02517
type II secretion system protein D; In Gram-negative bacteria, proteins that have first ...
 30-604 0e+00

type II secretion system protein D; In Gram-negative bacteria, proteins that have first crossed the inner member by Sec-dependent protein transport can be exported across the outer membrane by type II secretion, also called the main terminal branch of the general secretion pathway. Members of this family are general secretion pathway protein D. In Yersinia enterocolitica, a second member of this family is part of a novel second type II secretion system specifically associated with virulence (See ). This family is closely homologous to the type IV pilus outer membrane secretin PilQ (TIGR02515) and to the type III secretion system pore YscC/HrcC (TIGR02516). [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274175 [Multi-domain]  Cd Length: 594  Bit Score: 678.34  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569    30 ANFNNADIRQFVEIVGQHLGKTILIDPSVQGTISVRSNDTFSQQEYYQFFLSILDLYGYSVITLDNGFLKVVRSANVKTS 109
Cdd:TIGR02517   1 LNFVDADISTVVKAISDLTGKNFIIDPRVKGKITIISPRPVTEDEAYQLFLSALRAQGFAVVPEGNGYKIVVPRAAAKLS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569   110 PGMIADSSRPGVG-DELVTRIVPLENVPARDLAPLLRQMMDAgsVGNVVHYEPSNVLILTGRASTINKLIEVIKRVDVIG 188
Cdd:TIGR02517  81 PGPIEDGPAPGVGgDQFVTRVFPLRNISASELVPVLRPLVSP--NGDVAAYPPTNTIVVTDYASNINRVARIIQQLDVDG 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569   189 TEKQQIIHLEYASAEDLAEILNQLISEshGKSQMPALLSAKIVADKRTNSLIISGPEKARQRITSLLKSLDVEESEEGNT 268
Cdd:TIGR02517 159 AGSVEVIPLKNASAVDIADVLNKLLGE--GGKTDGGGKLSVIAPDRRNNILIRAGSPEALERIKKLISQLDVPASEGGNV 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569   269 RVYYLKYAKATNLVEVLTGVSEKLKDEKGNARKPSSSGAMDN----------------VAITADEQTNSLVITADQSVQE 332
Cdd:TIGR02517 237 RVYYLRNADAEELAKTLQGVFGGGGNEPGSSSSPGLGGAVNPggsqsaqaassasggsVSGSADKATNSLIITASPQDYK 316

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569   333 KLATVIARLDIRRAQVLVEAIIVEVQDGNGLNLGVQWANKNVGAQQFTNTGLPIFNAAQGVADYKKNGGITSANPAWDMF 412
Cdd:TIGR02517 317 NIRAVIKQLDVRRAQVLVEAIIVEVSLDDALELGVQWLIAGTGGGVNFSTGSPNSGSLLGASASAISLGSAGIGLLVTSS 396

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569   413 SAYNGMAAGFFNGDWGVLLTALASNNKNDILATPSIVTLDNKLASFNVGQDVPVLSGSQ----TTSGDNVFNTVERKTVG 488
Cdd:TIGR02517 397 STTSGVGGTGGGPNLGVLLNALKQDTGFNVLSTPSLLTLDNQEAEINVGQEVPVLTGSYntgtGGTNANPFNTYQRKDVG 476

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569   489 TKLKVTPQVNEGDAVLLEIEQEVS--SVDSSSNSTLGPTFNTRTIQNAVLVKTGETVVLGGLLDDFSKEQVSKVPLLGDI 566
Cdd:TIGR02517 477 IKLKVTPQINEGGTVRLEIYQEVSsvAPTTVGSAASGPTFNKREIKTVVLVDNGDTVVLGGLIQDKTSESVTKVPLLGDI 556

                         570       580       590
                  ....*....|....*....|....*....|....*...
gi 90111569   567 PLVGQLFRYTSTERAKRNLMVFIRPTIIRDDDVYRSLS 604
Cdd:TIGR02517 557 PVLGWLFRSTTTERTKTNLMVFITPRIIRDPEDARALT 594
PulD COG1450
Type II secretory pathway component GspD/PulD (secretin) [Intracellular trafficking, secretion, ...
 275-615 3.18e-97

Type II secretory pathway component GspD/PulD (secretin) [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 441059 [Multi-domain]  Cd Length: 333  Bit Score: 301.46  E-value: 3.18e-97
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569 275 YAKATNLVEVLTGVSeklkdekgnarkpsssGAMDNVAITADEQTNSLVITADQSVQEKLATVIARLDIRRAQVLVEAII 354
Cdd:COG1450  24 YADAEDLAKVLRSLL----------------GGAAGVSVVADPRTNSLIVRATPEQLREIEELIEQLDVPRRQVLIEAKI 87

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569 355 VEVQDGNGLNLGVQWA--NKNVGAQQFTNTGLPIFNAAQGvadykknggitsanpawdmfSAYNGMAAGFFN-GDWGVLL 431
Cdd:COG1450  88 VEVSLSDLRELGIDWSalGGNGGGVNFGGTGSLGSLAAAG--------------------SLGGGLNLGLLGgGNFGALL 147

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569 432 TALASNNKNDILATPSIVTLDNKLASFNVGQDVPVLSGSQTTSG-DNVFNTVERKTVGTKLKVTPQVNEGDAVLLEIEQE 510
Cdd:COG1450 148 NALESNGDANVLSSPSILTLNNQEAVIKVGQTVPYVTGSTTTSStGNPTTTIEYVDVGITLKVTPQINEDGTVTLDINPE 227

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569 511 V--SSVDSSSNSTLGPTFNTRTIQNAVLVKTGETVVLGGLLDDFSKEQVSKVPLLGDIPLVGQLFRYTSTERAKRNLMVF 588
Cdd:COG1450 228 VssVTGSTTGGGNGLPTINKREISTTVRVKDGQTVVLGGLIRDEESESESKVPLLGDIPLLGRLFRSTSKSKEKTELVIF 307

                       330       340
                ....*....|....*....|....*..
gi 90111569 589 IRPTIIRDDDVYRSLSKEkYTRYRQEQ 615
Cdd:COG1450 308 ITPTIIRDGEDAQALTEE-YDRLRALQ 333
HofQ COG4796
Type II secretory pathway, component HofQ [Intracellular trafficking, secretion, and vesicular ...
 260-597 2.11e-62

Type II secretory pathway, component HofQ [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443824 [Multi-domain]  Cd Length: 570  Bit Score: 217.03  E-value: 2.11e-62
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569 260 VEESEEGNTRVYYLKYAKATNLVEVLTGVSEKLKDEKGNarkpsssgamdnvaITADEQTNSLVITADQSVQEKLATVIA 339
Cdd:COG4796 250 IEELEPLRTEYIQLNYAKASDLAKLLKGQRGSLLSERGS--------------VTVDERTNTLIVRDTPSKLEEIRRLIA 315

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569 340 RLDIRRAQVLVEAIIVEVQDGNGLNLGVQWanknvGAQQFTNTGLPIFNAAQGVADYKKNGGITSANPAWDM--FSAYNG 417
Cdd:COG4796 316 KLDIPVRQVLIEARIVEASDSFSRELGVRW-----GGSGANGTGNNRGGIGGSLNGTTAGTPLLPDGLNVNLpaANPAGS 390

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569 418 MAAGFFNGDWGVL----LTALASNNKNDILATPSIVTLDNKLASFNVGQDVP--VLSGSQTTSgdnvfntVERKTVGTKL 491
Cdd:COG4796 391 LGLTLAKLGGGRLldleLSALEAEGKGEIISSPRVITADQQEASIEQGTEIPyqESSSSGATS-------VEFKEAVLSL 463

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569 492 KVTPQVNEGDAVLLEIEQEVSSVDSSSNSTlGPTFNTRTIQNAVLVKTGETVVLGGLLDDFSKEQVSKVPLLGDIPLVGQ 571
Cdd:COG4796 464 EVTPQITPDGRIILDLDVSKDSPGETVAGG-VPAIDTKEIKTQVLVENGETVVLGGIYEQTESNSVDKVPFLGDIPLLGW 542

                       330       340
                ....*....|....*....|....*.
gi 90111569 572 LFRYTSTERAKRNLMVFIRPTIIRDD 597
Cdd:COG4796 543 LFKNTTKTDEKRELLIFITPRIVKDA 568
IV_pilus_PilQ TIGR02515
type IV pilus secretin (or competence protein) PilQ; A number of proteins homologous to PilQ ...
 233-595 1.93e-54

type IV pilus secretin (or competence protein) PilQ; A number of proteins homologous to PilQ are involved in type IV pilus formation, competence for transformation, type III secretion, and type II secretion (also called the main terminal branch of the general secretion pathway). Members of this family include PilQ itself, which is a component of the type IV pilus structure, from a number of species. In Haemophilus influenzae, the member of this family is associated with competence for transformation with exogenous DNA rather than with formation of a type IV pilus; the surface structure required for competence may be considered an unusual, incomplete type IV pilus structure. [Cell envelope, Surface structures]


Pssm-ID: 274173 [Multi-domain]  Cd Length: 418  Bit Score: 191.76  E-value: 1.93e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569   233 DKRTNSLII---SGPEKARQRITSLLKSLDVEESEEGNTRVYYLKYAKATNLVEVLTGV---SEKLKDEKGNarkpsssg 306
Cdd:TIGR02515  61 DKRRDGNIIyiaPLDELAAQEKDELEAKKQIENLEPLQTELIQLNYAKASDIAKVLTGVtggSGGLLSPRGS-------- 132

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569   307 amdnvaITADEQTNSLVITADQSVQEKLATVIARLDIRRAQVLVEAIIVEVQDGNGLNLGVQWANKNVGAQQFTNTGLPI 386
Cdd:TIGR02515 133 ------VTVDPRTNTLIVTDTPENLARIRKLIAELDIPVRQVLIEARIVEATDSFSRELGVRWGITDKNGNGNGTAGGIG 206

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569   387 FNAAQGVADYKKNGGITSANPAWDMFSAYNGMAAGFFNG---DWGVL----LTALASNNKNDILATPSIVTLDNKLASFN 459
Cdd:TIGR02515 207 GNNGTTATGAGGTGNPPFGDNLNVNLATATTAAGISFALgkiGSGRLldleLSALESEGKGEIISSPRVLTANNKEAKIE 286

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569   460 VGQDVPVlsgsQTTSGDNVFNTVERKTVgTKLKVTPQVNEGDAVLLEIEQEVSSVDSSSNSTLG-PTFNTRTIQNAVLVK 538
Cdd:TIGR02515 287 QGTEIPY----QQTSSSGATSVEFKEAV-LSLEVTPQITPDGRIIMDLLVSKDSPGVVAQAGGGvPAIDKQEINTQVLVK 361

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 90111569   539 TGETVVLGGLLDDFSKEQVSKVPLLGDIPLVGQLFRYTSTERAKRNLMVFIRPTIIR 595
Cdd:TIGR02515 362 NGETVVIGGIYEQTQTNSEDKVPLLGDIPVLGNLFKKTGKSDEKSELLIFITPRIVN 418
Secretin pfam00263
Bacterial type II and III secretion system protein;
433-594 3.42e-52

Bacterial type II and III secretion system protein;


Pssm-ID: 459738 [Multi-domain]  Cd Length: 159  Bit Score: 176.94  E-value: 3.42e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569   433 ALASNNKNDILATPSIVTLDNKLASFNVGQDVPVLSGSQTTSGDNVfnTVERKTVGTKLKVTPQVNEGDAVLLEIEQEVS 512
Cdd:pfam00263   1 ALEQNGKAKILSSPSLLTLDNQEASIKVGQEVPVPTTSTTGGTTTT--TVEFKDAGLSLKVTPQVTPDGTITLKINPEVS 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569   513 SVDSSSNSTlGPTFNTRTIQNAVLVKTGETVVLGGLLDDFSKEQVSKVPLLGDIPLVGQLFRYTSTERAKRNLMVFIRPT 592
Cdd:pfam00263  79 SPDGNGGNG-VPTINTREISTTVRVKDGQTVVIGGLIQEEDSETESKVPLLGDIPLLGALFRSTSKSKEKTELLIFITPR 157


                  ..
gi 90111569   593 II 594
Cdd:pfam00263 158 IV 159
IV PHA00019
phage assembly protein
 11-595 1.06e-50

phage assembly protein


Pssm-ID: 222772 [Multi-domain]  Cd Length: 428  Bit Score: 181.55  E-value: 1.06e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569   11 LLAALLMPCAGHAENEQYgaNFNNADIRQFVEIVGQHLGKTILIDPSVQGTISVRSNDtFSQQEYYQFFLSILDlygysv 90
Cdd:PHA00019   9 MLLFLLMFLSFSSFALPV--ELNNSPIREFVSWYSQQTGKSVVLGPDVKGNVTVYSAD-VNPANLPQFFDSVLR------ 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569   91 itlDNGFLKVvrsanvktspgmiadssrpGVGDELVTRIVPLENVPARDLAPLLRQMMDAGSVgNVVHYEPSNVLILtgr 170
Cdd:PHA00019  80 ---ANGFDLV-------------------AGGPAVVIKQNPNQEDYADDLRDSRDDVFYDNSV-PSGAPEVPNDLIV--- 133

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569  171 astinklievikrvdvigtekqQIIHLEYASAEDLAEIlnqliseshgksqmpallsakivadkrtnsliisgpekarqr 250
Cdd:PHA00019 134 ----------------------RTFNINNVRASDLLPL------------------------------------------ 149

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569  251 ITSLLKSLDVeeseegntrvyylkyakatnlvevltgvseklkdekgnarkpsssgamDNVAITADEQTNSLVITADQSV 330
Cdd:PHA00019 150 VKIFVKSNGA------------------------------------------------PGGSVTDLPGTNSLVVSGSASQ 181

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569  331 QEKLATVIARLDIRRAQVLVEAIIVEVQDGNGLNLGVQWANKNVGAQQftntglpifnaaqgvadykknGGITSANPAWD 410
Cdd:PHA00019 182 LPALADFISAIDVPRRQVLIEALIFETSLGDGVDLSFAAGLASGGKVA---------------------GGFNTARLTTV 240

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569  411 MFSAynGMAAGFFNGD-WGVLLTALASNNKNDILATPSIVTLDNKLASFNVGQDVPVLSGSQT---TSGDNVFNTVERKT 486
Cdd:PHA00019 241 LSSA--GGSFGIFNGNvLGLSVKALENSSNSRVLSRPRILTLSGQSGYISVGQNVPFVTGRVTgeaANVNNPFQTIERKD 318

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569  487 VGTKLKVTPQVNEGDAVLLEIEQEVSSVDSSSNSTLGPTfNTRTIQNAVLVKTGETVVLGGLLDDFSKEQVSKVPLLGDI 566
Cdd:PHA00019 319 VGVSLEVTPVVMGDGQLVLDIDTKADSLSDSTIASDIIT-NQRSLQTTVQVKDGQTLLLGGLISSNNTDGDSSVPFLSKI 397

                        570       580
                 ....*....|....*....|....*....
gi 90111569  567 PLVGQLFRYTSTERAKRNLMVFIRPTIIR 595
Cdd:PHA00019 398 PLIGWLFRSKSDSNEQRTLYVLLTARVIK 426
type_III_yscC TIGR02516
type III secretion outer membrane pore, YscC/HrcC family; A number of proteins homologous to ...
 191-596 1.27e-35

type III secretion outer membrane pore, YscC/HrcC family; A number of proteins homologous to the type IV pilus secretin PilQ (TIGR02515) are involved in type IV pilus formation, competence for transformation, type III secretion, and type II secretion (also called the main terminal branch of the general secretion pathway). The clade described by this model contains the outer membrane pore proteins of bacterial type III secretion systems, typified by YscC for animal pathogens and HrcC for plant pathogens. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]


Pssm-ID: 274174 [Multi-domain]  Cd Length: 462  Bit Score: 140.20  E-value: 1.27e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569   191 KQQIIHLEYASAEDLAEILNQ--LISESHGKSQMPallsakivadkRTNSLIISGPEKARQRITSLLKSLD-VEESEEGN 267
Cdd:TIGR02516  76 ARAVISPRPLSANELKKALRRsgLYDPRFPWRGDP-----------EEGTVYVSGPPAYIDLVRNAATALEkQDQGRAGN 144

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569   268 T---RVYYLKYAKAT----NLVE---VLTGVSEKLKDEKGNARKPSSSGAMD-NVAITADEQTNSLVITADQSVQEKLAT 336
Cdd:TIGR02516 145 RqvvKVFPLKYASASdrtyNYRDqkvTIPGVATILRRLLSGGRQGAGGGRASaSPKISADPRTNAVLIRDRPERMAIYEQ 224

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569   337 VIARLDIRRAQVLVEAIIVEVQDGNGLNLGVQW--ANKNVGAQQFTNTGLPIFNAAQGvadykknggitsanpawdmfSA 414
Cdd:TIGR02516 225 LIQQLDVPPRLIEISAWIIDIDASDLSQLGVDWqaTLGAGDRQTGFNVSAGAGLGATG--------------------SS 284

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569   415 YNGMAAGFFNGDwgvlLTALASNNKNDILATPSIVTLDNKLASFNVGQDVPV-LSGSQTTSGDNVfntverkTVGTKLKV 493
Cdd:TIGR02516 285 IVTSDGDYFMAR----VNALEQTGKAKIVSRPSVLTLENVQAVLDNNRTFYVkVSGERVADLESV-------TAGTSLRV 353

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569   494 TPQVNEGDAVLLEIE-----QEVSSVDSSSNSTLG-PTFNTRTIQNAVLVKTGETVVLGGLLDDFSKEQVSKVPLLGDIP 567
Cdd:TIGR02516 354 TPRVIGDEGAQRQIKlnvdiEDGQQKTDGTSTVDAlPEIKRTEINTQARVGHGQSLLIGGYYRDESADSVDGIPLLGDIP 433

                         410       420
                  ....*....|....*....|....*....
gi 90111569   568 LVGQLFRYTSTERAKRNLMVFIRPTIIRD 596
Cdd:TIGR02516 434 LLGNLFRSTSKEKSRVVRLFLITPKIVRD 462
CpaC COG4964
Flp pilus assembly protein, secretin CpaC [Intracellular trafficking, secretion, and vesicular ...
 337-595 8.17e-35

Flp pilus assembly protein, secretin CpaC [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 443990 [Multi-domain]  Cd Length: 456  Bit Score: 137.69  E-value: 8.17e-35
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569 337 VIARLDIRRA-QVLVEAIIVEVQDGNGLNLGVQWANKNvgaqqftNTGLPIFNAAqgvadykkNGGITSANPAWDMFSAY 415
Cdd:COG4964 165 VINLLTVGGPqQVMLKVRVAEVSRSVLKQLGINWSGLG-------SSGGFSFGLL--------TGGLLSGLLGGATAGAF 229

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569 416 NGMAAGffNGDWGVLLTALASNNKNDILATPSIVTLDNKLASFNVGQDVPVlsgsQTTSGDNVFnTVERKTVGTKLKVTP 495
Cdd:COG4964 230 SGFGFG--NASISATLDALEQNGLARVLAEPNLTALSGETASFLAGGEFPI----PVAQGDGTI-TVEYKEFGVSLNFTP 302

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569 496 QVNEGDAVLLEIEQEVSSVDSSSNSTLG----PTFNTRTIQNAVLVKTGETVVLGGLLDDFSKEQVSKVPLLGDIPLVGQ 571
Cdd:COG4964 303 TVLSNGRISLKVAPEVSELDPSNAVTLNgitiPGLTTRRAETTVELRSGQSFAIAGLLSSNTRQNVSKVPGLGDIPILGA 382

                       250       260
                ....*....|....*....|....
gi 90111569 572 LFRYTSTERAKRNLMVFIRPTIIR 595
Cdd:COG4964 383 LFRSRSFQRNETELVIIVTPYLVK 406
hofQ PRK13568
DNA uptake porin HofQ;
267-597 7.66e-34

DNA uptake porin HofQ;


Pssm-ID: 237430 [Multi-domain]  Cd Length: 381  Bit Score: 133.32  E-value: 7.66e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569  267 NTRVYYLKYAKATNLVEVLTGVSEKLKDEKGNarkpsssgamdnvaITADEQTNSLVITADQSVQEKLATVIARLDIRRA 346
Cdd:PRK13568  83 ANLTLTLQYADAEEVADSLQSQRGGLLSPRGS--------------VTADKRTNTLLIRDTPAALAQLKNWLIELDLPLQ 148

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569  347 QVLVEAIIVEVQDGNGLNLGVQW-------ANKNVGAQQFtNTGLPIFNAAqgvadykknggitsanpawdmfsayngMA 419
Cdd:PRK13568 149 QVQLAAHIVTISSESLQELGVRWgmgegkqGNTALRINDF-NVNLPLPNPA---------------------------AS 200

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569  420 AGF----FNGDWGVL-LTALASNNKNDILATPSIVTLDNKLASFNVGQDVPVlsgsQTTSGDNVFNTVERKTVGTKLKVT 494
Cdd:PRK13568 201 AGFhlarLGGRLLDLeLSALEQENQVDIIASPRLFTSHQQTASIKQGTEIPY----TVSSGKSGSTSIEFKEAVLGMEVT 276

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569  495 PQVNEGDAVLL--EIEQEVSSVDSSSNSTLGPTFNTRTIQNAVLVKTGETVVLGGLLDDFSKEQVSKVPLLGDIPLVGQL 572
Cdd:PRK13568 277 PKILRNGRITLklKISQNMPGRTIKRGEGEMLAIDKQEIQTQVTVKDGETIVLGGIFQQQKRQSVNKVPLLGDIPLLGAL 356

                        330       340
                 ....*....|....*....|....*
gi 90111569  573 FRYTSTERAKRNLMVFIRPTIIRDD 597
Cdd:PRK13568 357 FRQDTQQQSRRELVIFITPKLISAD 381
PRK15346 PRK15346
EscC/YscC/HrcC family type III secretion system outer membrane ring protein;
191-579 1.27e-29

EscC/YscC/HrcC family type III secretion system outer membrane ring protein;


Pssm-ID: 237950 [Multi-domain]  Cd Length: 499  Bit Score: 122.88  E-value: 1.27e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569  191 KQQIIHLEYASAEDLAEILNqliseshgKSQMPALLSAKIVADKRTNSLIISGPEKARQRITSLLKSLDVE-ESEEGN-- 267
Cdd:PRK15346 105 KRQVITPTYLSAGRLIKYLQ--------SQGILNGKSCEVKAITGTNALEVSGVPECIERVTQLAKVLDEQaQKRKQNke 176

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569  268 -TRVYYLKYAKATN--------------LVEVL----TGVSEKLKDEKGNARKPSSSGamdNVAITADEQTNSlVITADQ 328
Cdd:PRK15346 177 tVKVFPLKYASATDttyqyrdqnvvvpgVVSVLremaQGNSLPLPGSNAVEGSPASQA---LPVFSADPRQNA-VIVRDR 252

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569  329 SVQEKL-ATVIARLDIRRAQVLVEAIIVEVQDGNGLNLGVQW-ANKNVGAQQFTntglpiFNAAQGVADYkknggitsan 406
Cdd:PRK15346 253 AANMAIyRSLITQLDQRPQMIEISVSIIDVDAGDINQLGIDWsASASLGGGKIS------FNSGFADGNA---------- 316

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569  407 pawDMFSAYNGMAAGFFngdwgVLLTALASNNKNDILATPSIVTLDNKLAsfnvgqdvpVLSGSQT----TSGDNVfNTV 482
Cdd:PRK15346 317 ---SGFSTVISNTGNFM-----VRLNALEKNSKAKILSQPSVVTLNNIQA---------VLDKNVTfytkLQGEKV-AKL 378

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569  483 ERKTVGTKLKVTPQV---NEGDAVLL--EIEQEVSSVDSSSNSTLGPTFNTRTIQNAVLvKTGETVVLGGLLDDFSKEQV 557
Cdd:PRK15346 379 ESITTGSLLRVTPRLiddNGTQKVMLnlNIQDGQQSATQSETDPLPEVQNSEIATQATL-KAGQSLLLGGFIQDKQIESQ 457

                        410       420
                 ....*....|....*....|..
gi 90111569  558 SKVPLLGDIPLVGQLFRYTSTE 579
Cdd:PRK15346 458 NKIPLLGDIPLIGGLFRSTDKQ 479
pilus_MshL TIGR02519
pilus (MSHA type) biogenesis protein MshL; Members of this family are predicted secretins, ...
 316-594 1.44e-29

pilus (MSHA type) biogenesis protein MshL; Members of this family are predicted secretins, that is, outer membrane pore proteins associated with delivery of proteins from periplasm to the outside of the cell. Related families include GspD of type II secretion (TIGR02517), the YscC/HrcC family from type III secretion (TIGR02516), and the PilQ secretin of type IV pilus formation (TIGR02515). Members of this family are found in gene clusters associated with MSHA (mannose-sensitive hemagglutinin) and related pili, and appear to be the secretin of this pilus system. [Cell envelope, Surface structures]


Pssm-ID: 274176 [Multi-domain]  Cd Length: 290  Bit Score: 118.64  E-value: 1.44e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569   316 DEQTNSLVITADQSVQEKLATVIARLDIR-RAQVLVEAIIVEVQDGNGLNLGVQWANknvgaqqFTNTGLPIFNAAQGVA 394
Cdd:TIGR02519   4 NPEAGLLTVTATPAQIRRVEEYLESLQERiHRQVLIEAKILEVTLSDNHQQGIDWSN-------FNGSGLARYKALGAAN 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569   395 DYKKNGGI-TSANPAWDMFSAYNGMaagFFNGDWGVLLTALASNNKNDILATPSIVTLDNKLASFNVGQDVPVLS----- 468
Cdd:TIGR02519  77 SNDSSGNQfSSGLGFLDNIGLPTGV---NSGFGFDSIINFLATFGDTKVLSNPKVMALNNQPAVISVGDNIRYVTeesst 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569   469 -----GSQTTSGDNVFNTVerkTVGTKLKVTPQVNEGDAVLLEI----------EQEVSSVDSSSNSTLgPTFNTRTIQN 533
Cdd:TIGR02519 154 gttggTTSTASSDTRVDSV---FSGIVLGVTPQISDDGKVILNVhpsisevkpqSIDLNPVGNGAEVAL-PEISVKEMSS 229

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 90111569   534 AVLVKTGETVVLGGLLDDFSKEQVSKVPLLGDIPLVGQLFRYTSTERAKRNLMVFIRPTII 594
Cdd:TIGR02519 230 VLRVKDGDTVVLGGLIDKKKSNTKTGLPFLGDIPGLGYLFGYKSKSKKKTELVIIIRPSVV 290
hofQ PRK10560
outer membrane porin HofQ; Provisional
 245-594 1.02e-25

outer membrane porin HofQ; Provisional


Pssm-ID: 182549 [Multi-domain]  Cd Length: 386  Bit Score: 109.52  E-value: 1.02e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569  245 EKARQRitsLLKSLDVEeseegnTRVYYLKYAKATNLVEVltgvSEKLKDEKGNarkpsssgamdnvaITADEQTNSLVI 324
Cdd:PRK10560  79 EAEQAR---AQANLPLE------NRSITLQYADAGELAKA----GEKLLSAKGS--------------MTVDKRTNRLLL 131

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569  325 TADQSVQEKLATVIARLDIRRAQVLVEAIIVEVQDGNGLNLGVQWANKNvgAQQFTNTGLPIFNAAqgvaDYKKNGGITS 404
Cdd:PRK10560 132 RDNKTALSALEQWVAQMDLPVGQVELAAHIVTINEKSLRELGVKWTLAD--AQQAGGVGQVTTLGS----DLSVATATTR 205

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569  405 AnpawdmfsaynGMAAGFFNGDWGVL-LTALASNNKNDILATPSIVTLDNKLASFNVGQDVPVlsgsQTTSGDNVFNTVE 483
Cdd:PRK10560 206 V-----------GFNIGRINGRLLDLeLSALEQKQQLDIIASPRLLASHLQPASIKQGSEIPY----QVSSGESGATSVE 270

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569  484 RKTVGTKLKVTPQVNEGDAVLLE--IEQEVSSVDSSSNSTLGPTFNTRTIQNAVLVKTGETVVLGGLLDDFSKEQVSKVP 561
Cdd:PRK10560 271 FKEAVLGMEVTPTVLQKGRIRLKlhISQNVPGQVLQQADGEVLAIDKQEIETQVEVKSGETLALGGIFSRKNKSGQDSVP 350

                        330       340       350
                 ....*....|....*....|....*....|...
gi 90111569  562 LLGDIPLVGQLFRYTSTERAKRNLMVFIRPTII 594
Cdd:PRK10560 351 LLGDIPWLGQLFRHDGKEDERRELVVFITPRLV 383
Secretin_N pfam03958
Bacterial type II/III secretion system short domain; This is a short, often repeated, domain ...
 193-264 1.30e-13

Bacterial type II/III secretion system short domain; This is a short, often repeated, domain found in bacterial type II/III secretory system proteins. All previous NolW-like domains fall into this family.


Pssm-ID: 461109 [Multi-domain]  Cd Length: 68  Bit Score: 66.09  E-value: 1.30e-13
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 90111569   193 QIIHLEYASAEDLAEILNQLISESHGKSQMPallsaKIVADKRTNSLIISGPEKARQRITSLLKSLDVEESE 264
Cdd:pfam03958   2 RVIPLKYASAEDLASALRSLLGGSGLLSKRG-----SVVADPRTNSLIVSGPPEYVELVRQLIKQLDVPRAQ 68
Secretin_N pfam03958
Bacterial type II/III secretion system short domain; This is a short, often repeated, domain ...
 268-347 1.17e-11

Bacterial type II/III secretion system short domain; This is a short, often repeated, domain found in bacterial type II/III secretory system proteins. All previous NolW-like domains fall into this family.


Pssm-ID: 461109 [Multi-domain]  Cd Length: 68  Bit Score: 60.31  E-value: 1.17e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569   268 TRVYYLKYAKATNLVEVLTGVSEKLKDEKGNARkpsssgamdnvaITADEQTNSLVITADQSVQEKLATVIARLDIRRAQ 347
Cdd:pfam03958   1 TRVIPLKYASAEDLASALRSLLGGSGLLSKRGS------------VVADPRTNSLIVSGPPEYVELVRQLIKQLDVPRAQ 68
PRK15339 PRK15339
EscC/YscC/HrcC family type III secretion system outer membrane ring protein;
303-622 7.86e-11

EscC/YscC/HrcC family type III secretion system outer membrane ring protein;


Pssm-ID: 237948 [Multi-domain]  Cd Length: 559  Bit Score: 64.79  E-value: 7.86e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569  303 SSSGAMDNVAITADEQTNSLVITADQSVQEKLATVIARLDIRRAQVLVEAIIVEVQDGNGLNLGVQWanknvgaqqftnt 382
Cdd:PRK15339 258 KQNAAAGDIKIIAYPDTNSLLVKGTAEQVHFIEMLVKALDVAKRHVELSLWIIDLDKSDLEQLGVNW------------- 324

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569  383 glpifnaaQGVADYKKNGGITSANPAWDMFSAYNGMAAgffngdwgvlLTALASNNKNDILATPSIVTLDNKLASFNVGQ 462
Cdd:PRK15339 325 --------SGSITIGDKLGVSLNQSSISTLDGSRFIAA----------VMALEQKKKANVVSRPVVLTQENIPAIFDNNR 386

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569  463 DVPV-LSGSQTTSGDNVfntverkTVGTKLKVTPQVNEGDAV--LLEIE---QEVSSVDSSSNSTLGPTFNTRTIQNAVL 536
Cdd:PRK15339 387 TFYTkLVGERNVALEHV-------TYGTMISVLPRFSADGQIemSLDIEdgnEKTPQSDTTTSVDALPEVGRTLISTIAR 459

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111569  537 VKTGETVVLGGLLDDFSKEQVSKVPLLGDIPLVGQLFRYTSTERAKRNLMVFIRPTIIrDDDVYRSLSKEKYTRYRQEQQ 616
Cdd:PRK15339 460 VPQGKSLLIGGYTRDANTDEVQSIPFLGSLPLIGSLFRYSSKNKSNIVRVFLIEPREI-VEPLTPDASESANDILKQSGQ 538


                 ....*.
gi 90111569  617 QRIDGK 622
Cdd:PRK15339 539 WSGDDK 544
Secretin_N pfam03958
Bacterial type II/III secretion system short domain; This is a short, often repeated, domain ...
 127-186 7.94e-11

Bacterial type II/III secretion system short domain; This is a short, often repeated, domain found in bacterial type II/III secretory system proteins. All previous NolW-like domains fall into this family.


Pssm-ID: 461109 [Multi-domain]  Cd Length: 68  Bit Score: 58.00  E-value: 7.94e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 90111569   127 TRIVPLENVPARDLAPLLRQMM----DAGSVGNVVHYEPSNVLILTGRASTINKLIEVIKRVDV 186
Cdd:pfam03958   1 TRVIPLKYASAEDLASALRSLLggsgLLSKRGSVVADPRTNSLIVSGPPEYVELVRQLIKQLDV 64
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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