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Conserved domains on  [gi|16131294|ref|NP_417877|]
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DNA-binding transcriptional activator MalT [Escherichia coli str. K-12 substr. MG1655]

Protein Classification

HTH-type transcriptional regulator MalT( domain architecture ID 11480306)

HTH-type transcriptional regulator MalT regulates transcription of the maltose regulon and thus the uptake and catabolism of malto-oligosaccharides

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK04841 PRK04841
HTH-type transcriptional regulator MalT;
1-900 0e+00

HTH-type transcriptional regulator MalT;


:

Pssm-ID: 235315 [Multi-domain]  Cd Length: 903  Bit Score: 1639.28  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294    1 MLIPSKLSRPVRLDHTVVRERLLAKLSGANNFRLALITSPAGYGKTTLISQWAAGKNDIGWYSLDEGDNQQERFASYLIA 80
Cdd:PRK04841   1 MLIPSKLSRPVRLHNTVVRERLLAKLSGANNYRLVLVTSPAGYGKTTLISQWAAGKNNLGWYSLDESDNQPERFASYLIA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294   81 AVQQATNGHCAICETMAQKRQYASLTSLFAQLFIELAEWHSPLYLVIDDYHLITNPVIHESMRFFIRHQPENLTLVVLSR 160
Cdd:PRK04841  81 ALQQATNGHCSKSEALAQKRQYASLSSLFAQLFIELADWHQPLYLVIDDYHLITNPEIHEAMRFFLRHQPENLTLVVLSR 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294  161 NLPQLGIANLRVRDQLLEIGSQQLAFTHQEAKQFFDCRLSSPIEAAESSRICDDVSGWATALQLIALSARQNTHSAHKSA 240
Cdd:PRK04841 161 NLPPLGIANLRVRDQLLEIGSQQLAFDHQEAQQFFDQRLSSPIEAAESSRLCDDVEGWATALQLIALSARQNNSSLHDSA 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294  241 RRLAGINASHLSDYLVDEVLDNVDLATRHFLLKSAILRSMNDALITRVTGEENGQMRLEEIERQGLFLQRMDDTGEWFCY 320
Cdd:PRK04841 241 RRLAGINASHLSDYLVEEVLDNVDLETRHFLLRCSVLRSMNDALIVRVTGEENGQMRLEELERQGLFIQRMDDSGEWFRY 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294  321 HPLFGNFLRQRCQWELAAELPEIHRAAAESWMAQGFPSEAIHHALAAGDALMLRDILLNHAWSLFNHSELSLLEESLKAL 400
Cdd:PRK04841 321 HPLFASFLRHRCQWELAQELPELHRAAAEAWLAQGFPSEAIHHALAAGDAQLLRDILLQHGWSLFNQGELSLLEECLNAL 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294  401 PWDSLLENPQLVLLQAWLMQSQHRYGEVNTLLARAEHEIKD---IREDTMHAEFNALRAQVAINDGNPDEAERLAKLALE 477
Cdd:PRK04841 401 PWEVLLENPRLVLLQAWLAQSQHRYSEVNTLLARAEQELKDrniELDGTLQAEFNALRAQVAINDGDPEEAERLAELALA 480

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294  478 ELPPGWFYSRIVATSVLGEVLHCKGELTRSLALMQQTEQMARQHDVWHYALWSLIQQSEILFAQGFLQTAWETQEKAFQL 557
Cdd:PRK04841 481 ELPLTWYYSRIVATSVLGEVHHCKGELARALAMMQQTEQMARQHDVYHYALWSLLQQSEILFAQGFLQAAYETQEKAFQL 560

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294  558 INEQHLEQLPMHEFLVRIRAQLLWAWARLDEAEASARSGIEVLSSYQPQQQLQCLAMLIQCSLARGDLDNARSQLNRLEN 637
Cdd:PRK04841 561 IEEQHLEQLPMHEFLLRIRAQLLWEWARLDEAEQCARKGLEVLSNYQPQQQLQCLAMLAKISLARGDLDNARRYLNRLEN 640

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294  638 LLGNGKYHSDWISNANKVRVIYWQMTGDKAAAANWLRHTAKPEFANNHFLQGQWRNIARAQILLGEFEPAEIVLEELNEN 717
Cdd:PRK04841 641 LLGNGRYHSDWIANADKVRLIYWQMTGDKEAAANWLRQAPKPEFANNHFLQGQWRNIARAQILLGQFDEAEIILEELNEN 720

                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294  718 ARSLRLMSDLNRNLLLLNQLYWQAGRKSDAQRVLLDALKLANRTGFISHFVIEGEAMAQQLRQLIQLNTLPELEQHRAQR 797
Cdd:PRK04841 721 ARSLRLMSDLNRNLILLNQLYWQQGRKSEAQRVLLEALKLANRTGFISHFVIEGEAMAQQLRQLIQLNTLPELEQHRAQR 800

                        810       820       830       840       850       860       870       880
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294  798 ILREINQHHRHKFAHFDENFVERLLNHPEVPELIRTSPLTQREWQVLGLIYSGYSNEQIAGELEVAATTIKTHIRNLYQK 877
Cdd:PRK04841 801 ILREINQHHRHKFAHFDEAFVEKLLNHPDVPELIRTSPLTQREWQVLGLIYSGYSNEQIAGELDVAATTIKTHIRNLYQK 880

                        890       900
                 ....*....|....*....|...
gi 16131294  878 LGVAHRQDAVQHAQQLLKMMGYG 900
Cdd:PRK04841 881 LGIAHRQEAVQHAQDLLKMMGYG 903
 
Name Accession Description Interval E-value
PRK04841 PRK04841
HTH-type transcriptional regulator MalT;
1-900 0e+00

HTH-type transcriptional regulator MalT;


Pssm-ID: 235315 [Multi-domain]  Cd Length: 903  Bit Score: 1639.28  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294    1 MLIPSKLSRPVRLDHTVVRERLLAKLSGANNFRLALITSPAGYGKTTLISQWAAGKNDIGWYSLDEGDNQQERFASYLIA 80
Cdd:PRK04841   1 MLIPSKLSRPVRLHNTVVRERLLAKLSGANNYRLVLVTSPAGYGKTTLISQWAAGKNNLGWYSLDESDNQPERFASYLIA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294   81 AVQQATNGHCAICETMAQKRQYASLTSLFAQLFIELAEWHSPLYLVIDDYHLITNPVIHESMRFFIRHQPENLTLVVLSR 160
Cdd:PRK04841  81 ALQQATNGHCSKSEALAQKRQYASLSSLFAQLFIELADWHQPLYLVIDDYHLITNPEIHEAMRFFLRHQPENLTLVVLSR 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294  161 NLPQLGIANLRVRDQLLEIGSQQLAFTHQEAKQFFDCRLSSPIEAAESSRICDDVSGWATALQLIALSARQNTHSAHKSA 240
Cdd:PRK04841 161 NLPPLGIANLRVRDQLLEIGSQQLAFDHQEAQQFFDQRLSSPIEAAESSRLCDDVEGWATALQLIALSARQNNSSLHDSA 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294  241 RRLAGINASHLSDYLVDEVLDNVDLATRHFLLKSAILRSMNDALITRVTGEENGQMRLEEIERQGLFLQRMDDTGEWFCY 320
Cdd:PRK04841 241 RRLAGINASHLSDYLVEEVLDNVDLETRHFLLRCSVLRSMNDALIVRVTGEENGQMRLEELERQGLFIQRMDDSGEWFRY 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294  321 HPLFGNFLRQRCQWELAAELPEIHRAAAESWMAQGFPSEAIHHALAAGDALMLRDILLNHAWSLFNHSELSLLEESLKAL 400
Cdd:PRK04841 321 HPLFASFLRHRCQWELAQELPELHRAAAEAWLAQGFPSEAIHHALAAGDAQLLRDILLQHGWSLFNQGELSLLEECLNAL 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294  401 PWDSLLENPQLVLLQAWLMQSQHRYGEVNTLLARAEHEIKD---IREDTMHAEFNALRAQVAINDGNPDEAERLAKLALE 477
Cdd:PRK04841 401 PWEVLLENPRLVLLQAWLAQSQHRYSEVNTLLARAEQELKDrniELDGTLQAEFNALRAQVAINDGDPEEAERLAELALA 480

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294  478 ELPPGWFYSRIVATSVLGEVLHCKGELTRSLALMQQTEQMARQHDVWHYALWSLIQQSEILFAQGFLQTAWETQEKAFQL 557
Cdd:PRK04841 481 ELPLTWYYSRIVATSVLGEVHHCKGELARALAMMQQTEQMARQHDVYHYALWSLLQQSEILFAQGFLQAAYETQEKAFQL 560

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294  558 INEQHLEQLPMHEFLVRIRAQLLWAWARLDEAEASARSGIEVLSSYQPQQQLQCLAMLIQCSLARGDLDNARSQLNRLEN 637
Cdd:PRK04841 561 IEEQHLEQLPMHEFLLRIRAQLLWEWARLDEAEQCARKGLEVLSNYQPQQQLQCLAMLAKISLARGDLDNARRYLNRLEN 640

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294  638 LLGNGKYHSDWISNANKVRVIYWQMTGDKAAAANWLRHTAKPEFANNHFLQGQWRNIARAQILLGEFEPAEIVLEELNEN 717
Cdd:PRK04841 641 LLGNGRYHSDWIANADKVRLIYWQMTGDKEAAANWLRQAPKPEFANNHFLQGQWRNIARAQILLGQFDEAEIILEELNEN 720

                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294  718 ARSLRLMSDLNRNLLLLNQLYWQAGRKSDAQRVLLDALKLANRTGFISHFVIEGEAMAQQLRQLIQLNTLPELEQHRAQR 797
Cdd:PRK04841 721 ARSLRLMSDLNRNLILLNQLYWQQGRKSEAQRVLLEALKLANRTGFISHFVIEGEAMAQQLRQLIQLNTLPELEQHRAQR 800

                        810       820       830       840       850       860       870       880
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294  798 ILREINQHHRHKFAHFDENFVERLLNHPEVPELIRTSPLTQREWQVLGLIYSGYSNEQIAGELEVAATTIKTHIRNLYQK 877
Cdd:PRK04841 801 ILREINQHHRHKFAHFDEAFVEKLLNHPDVPELIRTSPLTQREWQVLGLIYSGYSNEQIAGELDVAATTIKTHIRNLYQK 880

                        890       900
                 ....*....|....*....|...
gi 16131294  878 LGVAHRQDAVQHAQQLLKMMGYG 900
Cdd:PRK04841 881 LGIAHRQEAVQHAQDLLKMMGYG 903
TPR_MalT pfam17874
MalT-like TPR region; This entry contains a series of TPR repeats.
 449-781 1.41e-101

MalT-like TPR region; This entry contains a series of TPR repeats.


Pssm-ID: 436107 [Multi-domain]  Cd Length: 336  Bit Score: 319.64  E-value: 1.41e-101
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294   449 AEFNALRAQVAINDGNPDEAERLAKLALEELPPGWFYSRIVATSVLGEVLHCKGELTRSLALMQQTEQMARQHDVWHYAL 528
Cdd:pfam17874   1 GEIAALRAQLAISKGDAERALELAEQALALLPEDDLLARGLATFVLGEAYLCLGDLDAALQAMREAEALARRADSPHVTL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294   529 WSLIQQSEILFAQGFLQTAWETQEKAFQLINEQHLEQLPMHEFLVRIRAQLLWAWARLDEAEASARSGIEVLSSYQPQQQ 608
Cdd:pfam17874  81 WALLQQGEILRAQGRLHQALETYQQALQLARDHGLQHLPLHGFLLVGLADLLYEWNDLEEAEQHAQQGIQLGRQWEPDAA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294   609 LQCLAMLIQCSLARGDLDNARSQLNRLENLLGNGKYHSDWISNANKVRVIYWQMTGDKAAAANWLRHTAKPEFANNHFLQ 688
Cdd:pfam17874 161 VDAYVLLARIALAQGELEEALTLLRRAELLARQSFFHVDWLANAERVRVRLWLARGDLRAAVRWLRAAEPPSDADNHFLE 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294   689 GQWRNIARAQILLGEFEPAEIVLEELNENARSLRLMSDLNRNLLLLNQLYWQAGRKSDAQRVLLDALKLANRTGFISHFV 768
Cdd:pfam17874 241 RELRNLARVLLALGRFDDALSLLERLQNLAEQLGRVRSLIENLILQALALLALGRPDEALQALLDALSLAEPEGYVRSFV 320

                         330
                  ....*....|...
gi 16131294   769 IEGEAMAQQLRQL 781
Cdd:pfam17874 321 DEGAPLARLLKRL 333
HTH_LUXR smart00421
helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon
 835-890 7.25e-17

helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon


Pssm-ID: 197715 [Multi-domain]  Cd Length: 58  Bit Score: 75.26  E-value: 7.25e-17
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 16131294    835 PLTQREWQVLGLIYSGYSNEQIAGELEVAATTIKTHIRNLYQKLGVAHRQDAVQHA 890
Cdd:smart00421   3 SLTPREREVLRLLAEGLTNKEIAERLGISEKTVKTHLSNIMRKLGVRSRTQAVRLA 58
CitB COG2197
DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal ...
 836-893 1.08e-16

DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal transduction mechanisms, Transcription];


Pssm-ID: 441799 [Multi-domain]  Cd Length: 131  Bit Score: 77.24  E-value: 1.08e-16
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 16131294 836 LTQREWQVLGLIYSGYSNEQIAGELEVAATTIKTHIRNLYQKLGVAHRQDAVQHAQQL 893
Cdd:COG2197  70 LTPREREVLRLLAEGLSNKEIAERLGISERTVKTHVSNILRKLGVRNRTELVLLALRL 127
LuxR_C_like cd06170
C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix ...
 836-892 6.43e-16

C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many are active as homodimers. Many are two domain proteins in which the DNA binding property of the C-terminal DNA binding domain is modulated by modifications of the N-terminal domain. For example in the case of Lux R which participates in the regulation of gene expression in response to fluctuations in cell-population density (quorum-sensing), a signaling molecule, the pheromone Acyl HSL (N-acyl derivatives of homoserine lactone), binds to the N-terminal domain and leads to LuxR dimerization. For others phophorylation of the N-terminal domain leads to multimerization, for example Escherichia coli NarL and Sinorhizobium melilot FixJ. NarL controls gene expression of many respiratory-related operons when environmental nitrate or nitrite is present under anerobic conditions. FixJ is involved in the transcriptional activation of nitrogen fixation genes. The group also includes small proteins which lack an N-terminal signaling domain, such as Bacillus subtilis GerE. GerE is dimeric and acts in conjunction with sigmaK as an activator or a repressor modulating the expression of various genes in particular those encoding the spore-coat. These LuxR family regulators may share a similar organization of their target binding sites. For example the LuxR dimer binds the lux box, a 20bp inverted repeat, GerE dimers bind two 12bp consensus sequences in inverted orientation having the central four bases overlap, and the NarL dimer binds two 7bp inverted repeats separated by 2 bp.


Pssm-ID: 99777 [Multi-domain]  Cd Length: 57  Bit Score: 72.57  E-value: 6.43e-16
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 16131294 836 LTQREWQVLGLIYSGYSNEQIAGELEVAATTIKTHIRNLYQKLGVAHRQDAVQHAQQ 892
Cdd:cd06170   1 LTPREREVLRLLAEGKTNKEIADILGISEKTVKTHLRNIMRKLGVKSRTQLVAYAIR 57
 
Name Accession Description Interval E-value
PRK04841 PRK04841
HTH-type transcriptional regulator MalT;
1-900 0e+00

HTH-type transcriptional regulator MalT;


Pssm-ID: 235315 [Multi-domain]  Cd Length: 903  Bit Score: 1639.28  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294    1 MLIPSKLSRPVRLDHTVVRERLLAKLSGANNFRLALITSPAGYGKTTLISQWAAGKNDIGWYSLDEGDNQQERFASYLIA 80
Cdd:PRK04841   1 MLIPSKLSRPVRLHNTVVRERLLAKLSGANNYRLVLVTSPAGYGKTTLISQWAAGKNNLGWYSLDESDNQPERFASYLIA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294   81 AVQQATNGHCAICETMAQKRQYASLTSLFAQLFIELAEWHSPLYLVIDDYHLITNPVIHESMRFFIRHQPENLTLVVLSR 160
Cdd:PRK04841  81 ALQQATNGHCSKSEALAQKRQYASLSSLFAQLFIELADWHQPLYLVIDDYHLITNPEIHEAMRFFLRHQPENLTLVVLSR 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294  161 NLPQLGIANLRVRDQLLEIGSQQLAFTHQEAKQFFDCRLSSPIEAAESSRICDDVSGWATALQLIALSARQNTHSAHKSA 240
Cdd:PRK04841 161 NLPPLGIANLRVRDQLLEIGSQQLAFDHQEAQQFFDQRLSSPIEAAESSRLCDDVEGWATALQLIALSARQNNSSLHDSA 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294  241 RRLAGINASHLSDYLVDEVLDNVDLATRHFLLKSAILRSMNDALITRVTGEENGQMRLEEIERQGLFLQRMDDTGEWFCY 320
Cdd:PRK04841 241 RRLAGINASHLSDYLVEEVLDNVDLETRHFLLRCSVLRSMNDALIVRVTGEENGQMRLEELERQGLFIQRMDDSGEWFRY 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294  321 HPLFGNFLRQRCQWELAAELPEIHRAAAESWMAQGFPSEAIHHALAAGDALMLRDILLNHAWSLFNHSELSLLEESLKAL 400
Cdd:PRK04841 321 HPLFASFLRHRCQWELAQELPELHRAAAEAWLAQGFPSEAIHHALAAGDAQLLRDILLQHGWSLFNQGELSLLEECLNAL 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294  401 PWDSLLENPQLVLLQAWLMQSQHRYGEVNTLLARAEHEIKD---IREDTMHAEFNALRAQVAINDGNPDEAERLAKLALE 477
Cdd:PRK04841 401 PWEVLLENPRLVLLQAWLAQSQHRYSEVNTLLARAEQELKDrniELDGTLQAEFNALRAQVAINDGDPEEAERLAELALA 480

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294  478 ELPPGWFYSRIVATSVLGEVLHCKGELTRSLALMQQTEQMARQHDVWHYALWSLIQQSEILFAQGFLQTAWETQEKAFQL 557
Cdd:PRK04841 481 ELPLTWYYSRIVATSVLGEVHHCKGELARALAMMQQTEQMARQHDVYHYALWSLLQQSEILFAQGFLQAAYETQEKAFQL 560

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294  558 INEQHLEQLPMHEFLVRIRAQLLWAWARLDEAEASARSGIEVLSSYQPQQQLQCLAMLIQCSLARGDLDNARSQLNRLEN 637
Cdd:PRK04841 561 IEEQHLEQLPMHEFLLRIRAQLLWEWARLDEAEQCARKGLEVLSNYQPQQQLQCLAMLAKISLARGDLDNARRYLNRLEN 640

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294  638 LLGNGKYHSDWISNANKVRVIYWQMTGDKAAAANWLRHTAKPEFANNHFLQGQWRNIARAQILLGEFEPAEIVLEELNEN 717
Cdd:PRK04841 641 LLGNGRYHSDWIANADKVRLIYWQMTGDKEAAANWLRQAPKPEFANNHFLQGQWRNIARAQILLGQFDEAEIILEELNEN 720

                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294  718 ARSLRLMSDLNRNLLLLNQLYWQAGRKSDAQRVLLDALKLANRTGFISHFVIEGEAMAQQLRQLIQLNTLPELEQHRAQR 797
Cdd:PRK04841 721 ARSLRLMSDLNRNLILLNQLYWQQGRKSEAQRVLLEALKLANRTGFISHFVIEGEAMAQQLRQLIQLNTLPELEQHRAQR 800

                        810       820       830       840       850       860       870       880
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294  798 ILREINQHHRHKFAHFDENFVERLLNHPEVPELIRTSPLTQREWQVLGLIYSGYSNEQIAGELEVAATTIKTHIRNLYQK 877
Cdd:PRK04841 801 ILREINQHHRHKFAHFDEAFVEKLLNHPDVPELIRTSPLTQREWQVLGLIYSGYSNEQIAGELDVAATTIKTHIRNLYQK 880

                        890       900
                 ....*....|....*....|...
gi 16131294  878 LGVAHRQDAVQHAQQLLKMMGYG 900
Cdd:PRK04841 881 LGIAHRQEAVQHAQDLLKMMGYG 903
TPR_MalT pfam17874
MalT-like TPR region; This entry contains a series of TPR repeats.
 449-781 1.41e-101

MalT-like TPR region; This entry contains a series of TPR repeats.


Pssm-ID: 436107 [Multi-domain]  Cd Length: 336  Bit Score: 319.64  E-value: 1.41e-101
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294   449 AEFNALRAQVAINDGNPDEAERLAKLALEELPPGWFYSRIVATSVLGEVLHCKGELTRSLALMQQTEQMARQHDVWHYAL 528
Cdd:pfam17874   1 GEIAALRAQLAISKGDAERALELAEQALALLPEDDLLARGLATFVLGEAYLCLGDLDAALQAMREAEALARRADSPHVTL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294   529 WSLIQQSEILFAQGFLQTAWETQEKAFQLINEQHLEQLPMHEFLVRIRAQLLWAWARLDEAEASARSGIEVLSSYQPQQQ 608
Cdd:pfam17874  81 WALLQQGEILRAQGRLHQALETYQQALQLARDHGLQHLPLHGFLLVGLADLLYEWNDLEEAEQHAQQGIQLGRQWEPDAA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294   609 LQCLAMLIQCSLARGDLDNARSQLNRLENLLGNGKYHSDWISNANKVRVIYWQMTGDKAAAANWLRHTAKPEFANNHFLQ 688
Cdd:pfam17874 161 VDAYVLLARIALAQGELEEALTLLRRAELLARQSFFHVDWLANAERVRVRLWLARGDLRAAVRWLRAAEPPSDADNHFLE 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294   689 GQWRNIARAQILLGEFEPAEIVLEELNENARSLRLMSDLNRNLLLLNQLYWQAGRKSDAQRVLLDALKLANRTGFISHFV 768
Cdd:pfam17874 241 RELRNLARVLLALGRFDDALSLLERLQNLAEQLGRVRSLIENLILQALALLALGRPDEALQALLDALSLAEPEGYVRSFV 320

                         330
                  ....*....|...
gi 16131294   769 IEGEAMAQQLRQL 781
Cdd:pfam17874 321 DEGAPLARLLKRL 333
GerE pfam00196
Bacterial regulatory proteins, luxR family;
834-890 4.26e-18

Bacterial regulatory proteins, luxR family;


Pssm-ID: 425517 [Multi-domain]  Cd Length: 57  Bit Score: 78.78  E-value: 4.26e-18
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 16131294   834 SPLTQREWQVLGLIYSGYSNEQIAGELEVAATTIKTHIRNLYQKLGVAHRQDAVQHA 890
Cdd:pfam00196   1 DSLSPREREVLRWLAAGKSNKEIADELGISEKTVKVHRSNIMRKLNVHSRVELVRMA 57
HTH_LUXR smart00421
helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon
 835-890 7.25e-17

helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon


Pssm-ID: 197715 [Multi-domain]  Cd Length: 58  Bit Score: 75.26  E-value: 7.25e-17
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 16131294    835 PLTQREWQVLGLIYSGYSNEQIAGELEVAATTIKTHIRNLYQKLGVAHRQDAVQHA 890
Cdd:smart00421   3 SLTPREREVLRLLAEGLTNKEIAERLGISEKTVKTHLSNIMRKLGVRSRTQAVRLA 58
CitB COG2197
DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal ...
 836-893 1.08e-16

DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal transduction mechanisms, Transcription];


Pssm-ID: 441799 [Multi-domain]  Cd Length: 131  Bit Score: 77.24  E-value: 1.08e-16
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 16131294 836 LTQREWQVLGLIYSGYSNEQIAGELEVAATTIKTHIRNLYQKLGVAHRQDAVQHAQQL 893
Cdd:COG2197  70 LTPREREVLRLLAEGLSNKEIAERLGISERTVKTHVSNILRKLGVRNRTELVLLALRL 127
GerE COG5905
Spore transcriptional regulator GerE (stand-alone HTH domain) [Cell cycle control, cell ...
 832-893 6.39e-16

Spore transcriptional regulator GerE (stand-alone HTH domain) [Cell cycle control, cell division, chromosome partitioning, Transcription];


Pssm-ID: 444607 [Multi-domain]  Cd Length: 76  Bit Score: 73.07  E-value: 6.39e-16
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 16131294 832 RTSPLTQREWQVLGLIYSGYSNEQIAGELEVAATTIKTHIRNLYQKLGVAHRQDAVQHAQQL 893
Cdd:COG5905   9 HPSLLTKREREVLELLAEGLTNKEIARQLFISEKTVKNHVSNILRKLGVRNRVQAVVWALRL 70
LuxR_C_like cd06170
C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix ...
 836-892 6.43e-16

C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many are active as homodimers. Many are two domain proteins in which the DNA binding property of the C-terminal DNA binding domain is modulated by modifications of the N-terminal domain. For example in the case of Lux R which participates in the regulation of gene expression in response to fluctuations in cell-population density (quorum-sensing), a signaling molecule, the pheromone Acyl HSL (N-acyl derivatives of homoserine lactone), binds to the N-terminal domain and leads to LuxR dimerization. For others phophorylation of the N-terminal domain leads to multimerization, for example Escherichia coli NarL and Sinorhizobium melilot FixJ. NarL controls gene expression of many respiratory-related operons when environmental nitrate or nitrite is present under anerobic conditions. FixJ is involved in the transcriptional activation of nitrogen fixation genes. The group also includes small proteins which lack an N-terminal signaling domain, such as Bacillus subtilis GerE. GerE is dimeric and acts in conjunction with sigmaK as an activator or a repressor modulating the expression of various genes in particular those encoding the spore-coat. These LuxR family regulators may share a similar organization of their target binding sites. For example the LuxR dimer binds the lux box, a 20bp inverted repeat, GerE dimers bind two 12bp consensus sequences in inverted orientation having the central four bases overlap, and the NarL dimer binds two 7bp inverted repeats separated by 2 bp.


Pssm-ID: 99777 [Multi-domain]  Cd Length: 57  Bit Score: 72.57  E-value: 6.43e-16
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 16131294 836 LTQREWQVLGLIYSGYSNEQIAGELEVAATTIKTHIRNLYQKLGVAHRQDAVQHAQQ 892
Cdd:cd06170   1 LTPREREVLRLLAEGKTNKEIADILGISEKTVKTHLRNIMRKLGVKSRTQLVAYAIR 57
MalT COG2909
ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT [Transcription];
125-223 3.21e-13

ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT [Transcription];


Pssm-ID: 442153 [Multi-domain]  Cd Length: 184  Bit Score: 68.96  E-value: 3.21e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294 125 LVIDDYHLITNpvIHesMRFFIRHQPENLTLVVLSRNLPqlgIANLRVRdqlLEIGSQQLAftHQEAKQFFDCRLsSPIE 204
Cdd:COG2909   2 LVLDDYHLIDD--IH--LAFLLRHLPPNLHLVLASRTDP---LARLRAR---LELRADDLR--REEAAALLRRRL-LPLS 68

                        90
                ....*....|....*....
gi 16131294 205 AAESSRICDDVSGWATALQ 223
Cdd:COG2909  69 EEDAARLAERTEGWARLAL 87
CsgD COG2771
DNA-binding transcriptional regulator, CsgD family [Transcription];
740-893 2.83e-12

DNA-binding transcriptional regulator, CsgD family [Transcription];


Pssm-ID: 442052 [Multi-domain]  Cd Length: 188  Bit Score: 66.32  E-value: 2.83e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294 740 QAGRKSDAQRVLLDALKLANRTGFISHFVIEGEAMAQQLRQLIQLNTLPELEQHRAQRILREINQHHRHKFAHFDENFVE 819
Cdd:COG2771  32 LLLLLALLLLAALLLLAAAAAALAAALAAALLLGLLLLLLIALLLLLLLLLALLLLLALLALLAALLARLAALLLALALA 111

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 16131294 820 RLLNHPEVPELIRTSPLTQREWQVLGLIYSGYSNEQIAGELEVAATTIKTHIRNLYQKLGVAHRQDAVQHAQQL 893
Cdd:COG2771 112 ALLLAALARLLARAPGLTPREREVLRLLAEGLTLKEIARILGISERTVRTHLKRIYRKLGVSSRAELVALALRL 185
MalT COG2909
ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT [Transcription];
846-893 5.54e-12

ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT [Transcription];


Pssm-ID: 442153 [Multi-domain]  Cd Length: 184  Bit Score: 65.50  E-value: 5.54e-12
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*...
gi 16131294 846 LIYSGYSNEQIAGELEVAATTIKTHIRNLYQKLGVAHRQDAVQHAQQL 893
Cdd:COG2909 133 LLAEGLSNKEIAERLFISVNTVKTHLRNIYRKLGVRSRTEAVARAREL 180
FixJ COG4566
DNA-binding response regulator, FixJ family, consists of REC and HTH domains [Signal ...
 814-893 1.40e-09

DNA-binding response regulator, FixJ family, consists of REC and HTH domains [Signal transduction mechanisms, Transcription];


Pssm-ID: 443623 [Multi-domain]  Cd Length: 196  Bit Score: 58.57  E-value: 1.40e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294 814 DENFVERLLNHPEVPELIRTspLTQREWQVLGLIYSGYSNEQIAGELEVAATTIKTHIRNLYQKLGVAHRQDAVQHAQQL 893
Cdd:COG4566 118 DRARRAERARRAELRARLAS--LTPREREVLDLVVAGLSNKQIARELGISPRTVEVHRANVMEKLGARSLAELVRLALAL 195
PRK10403 PRK10403
nitrate/nitrite response regulator protein NarP;
834-883 5.08e-07

nitrate/nitrite response regulator protein NarP;


Pssm-ID: 182431 [Multi-domain]  Cd Length: 215  Bit Score: 51.39  E-value: 5.08e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 16131294  834 SPLTQREWQVLGLIYSGYSNEQIAGELEVAATTIKTHIRNLYQKLGVAHR 883
Cdd:PRK10403 152 SVLTERELDVLHELAQGLSNKQIASVLNISEQTVKVHIRNLLRKLNVRSR 201
PRK10651 PRK10651
transcriptional regulator NarL; Provisional
 822-886 9.55e-07

transcriptional regulator NarL; Provisional


Pssm-ID: 182619 [Multi-domain]  Cd Length: 216  Bit Score: 50.80  E-value: 9.55e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 16131294  822 LNHPEVPELIRTSPLTQREWQVLGLIYSGYSNEQIAGELEVAATTIKTHIRNLYQKLGVAHRQDA 886
Cdd:PRK10651 142 LRANRATTERDVNQLTPRERDILKLIAQGLPNKMIARRLDITESTVKVHVKHMLKKMKLKSRVEA 206
PRK10100 PRK10100
transcriptional regulator CsgD;
833-895 1.99e-06

transcriptional regulator CsgD;


Pssm-ID: 182241 [Multi-domain]  Cd Length: 216  Bit Score: 49.87  E-value: 1.99e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 16131294  833 TSPLTQREWQVLGLIYSGYSNEQIAGELEVAATTIKTHIRNLYQKLGVAHRQDAVQHAQQLLK 895
Cdd:PRK10100 153 SALLTHREKEILNKLRIGASNNEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWANDNLR 215
PRK15369 PRK15369
two component system response regulator;
816-893 3.64e-05

two component system response regulator;


Pssm-ID: 185267 [Multi-domain]  Cd Length: 211  Bit Score: 45.84  E-value: 3.64e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294  816 NFVERLLNHPEVPELIRTSP-----LTQREWQVLGLIYSGYSNEQIAGELEVAATTIKTHIRNLYQKLGVAHRQDAVQHA 890
Cdd:PRK15369 125 RYIDPALNREAILALLNADDtnpplLTPRERQILKLITEGYTNRDIAEQLSISIKTVETHRLNMMRKLDVHKVAELLNWA 204


                 ...
gi 16131294  891 QQL 893
Cdd:PRK15369 205 RRL 207
PRK09935 PRK09935
fimbriae biosynthesis transcriptional regulator FimZ;
835-891 1.59e-04

fimbriae biosynthesis transcriptional regulator FimZ;


Pssm-ID: 182154 [Multi-domain]  Cd Length: 210  Bit Score: 43.71  E-value: 1.59e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 16131294  835 PLTQREWQVLGLIYSGYSNEQIAGELEVAATTIKTHIRNLYQKLGVAHRQDAVQHAQ 891
Cdd:PRK09935 149 VLSNREVTILRYLVSGLSNKEIADQLLLSNKTVSAHKSNIYGKLGLHSIVELIDYAK 205
PRK10360 PRK10360
transcriptional regulator UhpA;
832-882 1.94e-04

transcriptional regulator UhpA;


Pssm-ID: 182408 [Multi-domain]  Cd Length: 196  Bit Score: 43.43  E-value: 1.94e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 16131294  832 RTSPLTQREWQVLGLIYSGYSNEQIAGELEVAATTIKTHIRNLYQKLGVAH 882
Cdd:PRK10360 134 RQDPLTKRERQVAEKLAQGMAVKEIAAELGLSPKTVHVHRANLMEKLGVSN 184
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 449-598 4.50e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 41.33  E-value: 4.50e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294 449 AEFNALRAQVAINDGNPDEAERLAKLALEELPpgwfySRIVATSVLGEVLHCKGELTRSLALMQQTEQMARQHDVWHYAL 528
Cdd:COG4783   4 AEALYALAQALLLAGDYDEAEALLEKALELDP-----DNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNL 78

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294 529 wsliqqSEILFAQGFLQTAWETQEKAfqlineqhLEQLPMHEFLVRIRAQLLWAWARLDEAEASARSGIE 598
Cdd:COG4783  79 ------GLALLKAGDYDEALALLEKA--------LKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALE 134
COG3899 COG3899
Predicted ATPase [General function prediction only];
226-894 2.39e-03

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 41.77  E-value: 2.39e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294  226 ALSARQNTHSAHKSARRLAGINASHLSDYLVDEVLDNVDL---ATRHFLLKSAIL-RSMNDALITRVTGEENGQM--RLE 299
Cdd:COG3899  547 ALLEEGLLRFDGGGWRWDAALAALALPDTVVDLLAARLDRlppAARRVLRLAAVLgRRFDLELLAAVLGLSEAELaaALE 626

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294  300 EIERQGLFLQRMDDTGEWFC-YHPLFGNFLRQRCqweLAAELPEIHRAAAE------SWMAQGFPSEAIHHALAAGDAlm 372
Cdd:COG3899  627 ELVAAGLLVPRGDAGGGRYRfRHDLVREAAYASL---PPEERRALHRRIARaleargPEPLEERLFELAHHLNRAGER-- 701

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294  373 lrdillnhawslfnhselslleesLKALPWDsllenpqlvLLQAWLMQSQHRYGEVNTLLARAEHEIKDIREDTMHAEFN 452
Cdd:COG3899  702 ------------------------DRAARLL---------LRAARRALARGAYAEALRYLERALELLPPDPEEEYRLALL 748

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294  453 ALRAQVAINDGNPDEAERLAKLALEE--------LPPGWFYSRIVATSVLGEVLHckGELTRSLALMQQTEQMARQHDVW 524
Cdd:COG3899  749 LELAEALYLAGRFEEAEALLERALAAralaalaaLRHGNPPASARAYANLGLLLL--GDYEEAYEFGELALALAERLGDR 826

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294  525 HYALWSLIQQSEILFAQGFLQTAWETQEKAFQL---INEQHLEQLPMHEFLVRIRAQLLWAWARLDEAEASARSGIEVLS 601
Cdd:COG3899  827 RLEARALFNLGFILHWLGPLREALELLREALEAgleTGDAALALLALAAAAAAAAAAAALAAAAAAAARLLAAAAAALAA 906

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294  602 SYQPQQQLQCLAMLIQCSLARGDLDNARSQLNRLENLLGNGKYHSDWISNANKVRVIYWQMTGDKAAAANWLRHTAKPEF 681
Cdd:COG3899  907 AAAAAALAAAELARLAAAAAAAAALALAAAAAAAAAAALAAAAAAAALAAALALAAAAAAAAAAALAAAAAAAAAAAAAA 986

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294  682 ANNHFLQGQWRNIARAQILLGEFEPAEIVLEELNENARSLRLMSDLNRNLLLLNQLYWQAGRKSDAQRVLLDALKLANRT 761
Cdd:COG3899  987 AAAALEAAAAALLALLAAAAAAAAAAAALAAALLAAALAALAAAAAAAALLAAAAALALLAALAAAAAAAAAAAALAAAA 1066

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294  762 GFISHFVIEGEAMAQQLRQLIQLNTLPELEQHRAQRILREINQHHRHKFAHFDENFVERLLNHPEVPELIRTSPLTQREW 841
Cdd:COG3899 1067 ALLAAAAAAAAAAAAAAAAAALAAALAAAALAAAAAAALALAAALAALALAAALAALALAAAARAAAALLLLAAALALAL 1146

                        650       660       670       680       690
                 ....*....|....*....|....*....|....*....|....*....|...
gi 16131294  842 QVLGLIYSGYSNEQIAGELEVAATTIKTHIRNLYQKLGVAHRQDAVQHAQQLL 894
Cdd:COG3899 1147 AALLLLAALLLALALLLLALAALALAAALAALAAALLAAAAAAAAAAALLAAL 1199
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 370-618 2.94e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 41.13  E-value: 2.94e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294 370 ALMLRDILLNHAWSLFNHSELSLLEESLKALPWDSLLENPQLVLLQAWLMQSQHRYGevNTLLARAEHEIKDIREDTMHA 449
Cdd:COG3914   3 AAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAAL--LALAAGEAAAAAAALLLLAAL 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294 450 EFNALRAQVAIndGNPDEAERLAKLALEELPpgwfySRIVATSVLGEVLHCKGELTRSLALMQQTEQMARQHDVWHYALw 529
Cdd:COG3914  81 LELAALLLQAL--GRYEEALALYRRALALNP-----DNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNL- 152

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294 530 sliqqSEILFAQGFLQTAWETQEKAfqlineqhLEQLPMHEFLVRIRAQLLWAWARLDEAEASARSGIEVLSSYQPQQQL 609
Cdd:COG3914 153 -----GEALRRLGRLEEAIAALRRA--------LELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSN 219


                ....*....
gi 16131294 610 QCLAMLIQC 618
Cdd:COG3914 220 LLFALRQAC 228
Cohesin_load pfam10345
Cohesin loading factor; Cohesin_load is a common cohesin loading factor protein that is ...
 518-648 3.49e-03

Cohesin loading factor; Cohesin_load is a common cohesin loading factor protein that is conserved in fungi. It is associated with the cohesin complex and is required in G1 for cohesin binding to chromosomes but dispensable in G2 when cohesion has been established. It is referred to as both Ssl3, in pombe, and Scc4, in S.cerevisiae. It complexes with Mis4.


Pssm-ID: 463053 [Multi-domain]  Cd Length: 585  Bit Score: 41.15  E-value: 3.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294   518 ARQHDVWHYAL-----WSLIQQSEILFAqgfLQTAWETQEKAfQLINEQHLEQLPMH-EFLVRIRAQLLWAWARLDEAEA 591
Cdd:pfam10345 130 AYRHVHWVYAFrflraSLLLQENDYSAA---LENLQSISELA-EQRGDQAVRVVALLlEALLHLRSSPSDSLEEAQRALA 205

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 16131294   592 SARSGIEVLSSYQPQQqLQCLAMLIQ--CSLARGDLDNARSQLNRLENLLGNGKYHSDW 648
Cdd:pfam10345 206 AARSEQLQPSMQAIPQ-LRALLLLLDllCSLMQGNPKQITEKLKQLQSFIDNLKDWSNW 263
PRK11475 PRK11475
DNA-binding transcriptional activator BglJ; Provisional
 815-886 5.15e-03

DNA-binding transcriptional activator BglJ; Provisional


Pssm-ID: 236915 [Multi-domain]  Cd Length: 207  Bit Score: 39.34  E-value: 5.15e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 16131294  815 ENFVERLLNHPEVPELIRTSPlTQREwqVLGLIYSGYSNEQIAGELEVAATTIKTHIRNLYQKLGVahRQDA 886
Cdd:PRK11475 117 RQATDRLNNQWYINQSRMLSP-TERE--ILRFMSRGYSMPQIAEQLERNIKTIRAHKFNVMSKLGV--SSDA 183
COG1672 COG1672
Predicted ATPase, archaeal AAA+ ATPase superfamily [General function prediction only];
19-232 7.88e-03

Predicted ATPase, archaeal AAA+ ATPase superfamily [General function prediction only];


Pssm-ID: 441278 [Multi-domain]  Cd Length: 324  Bit Score: 39.51  E-value: 7.88e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294  19 RERLLAKLSGA---NNFRLALITSPAGYGKTTLISQWAAGKNDIgWYSLDEGDNQQ--ERFASYLIAAVqqatnghcaic 93
Cdd:COG1672   5 REEELEELEKLyesDGGELVVVYGRRRVGKTSLIKEFLKEKPAI-YFDAREESEREslRDFSEALAEAL----------- 72

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131294  94 ETMAQKRQYASLTSLFAQLFIELAEwhSPLYLVIDDY-HLIT-NPVIHESMRFFIRHQPE--NLTLV------------V 157
Cdd:COG1672  73 GDPLSKKEFESWEEAFEYLAELAEG--KRLVIVIDEFqYLVKlDPSLLSILQYLWDELLSdsNVSLIlcgssigmmeelL 150

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 16131294 158 LSRNLPqlgianLRVR-DQLLEIGsqqlAFTHQEAKQFF-DCRLSSPIEAAESSRICDDVSGWATALQLIALSARQN 232
Cdd:COG1672 151 LDYKSP------LYGRrTGEIKLK----PFSFEESKEFLpEGFEYSEEELEEAYSVLGGIPGYLTLFGNEGKSLEEN 217
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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