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Concise Results
Standard Results
Full Results
aerobic glycerol 3-phosphate dehydrogenase [Escherichia coli str. K-12 substr. MG1655]
Protein Classification
glycerol-3-phosphate dehydrogenase ( domain architecture ID 11485706 )
glycerol-3-phosphate dehydrogenase catalyzes the interconversion of glycerone phosphate and sn-glycerol-3-phosphate
List of domain hits
Name
Accession
Description
Interval
E-value
glpD
PRK12266 glycerol-3-phosphate dehydrogenase; Reviewed
27-501
0e+00
glycerol-3-phosphate dehydrogenase; Reviewed
Pssm-ID: 237027 [Multi-domain]
Cd Length: 508
Bit Score: 960.37
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 27 LSVL ML E AQ DLA C ATSSAS S KLIHGGLRYLEHYEFRLV S EALAEREVLL K MAPHI AF PMRF R LPHRPHLRPAWMIR I GLF 106
Cdd:PRK12266 30 LSVL LC E QD DLA S ATSSAS T KLIHGGLRYLEHYEFRLV R EALAEREVLL R MAPHI IW PMRF V LPHRPHLRPAWMIR A GLF 109
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 107 M YDHLGKR T SLPGS T GL RF G --- A N S V LKPEI K RGFEYSDCWVDDARLV LA NA QMVVRK G G E V LTRTR AT SARRENGLW I 183
Cdd:PRK12266 110 L YDHLGKR K SLPGS R GL DL G rdp A G S P LKPEI T RGFEYSDCWVDDARLV VL NA RDAAER G A E I LTRTR VV SARRENGLW H 189
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 184 V EA ED ID TGK K Y SWQ AR G LVNA T GPWVKQF F DDG MH LPSPYGIRL I KGSHIVVPR VHTQK QAYILQN E D K RIVF V IP WM D 263
Cdd:PRK12266 190 V TL ED TA TGK R Y TVR AR A LVNA A GPWVKQF L DDG LG LPSPYGIRL V KGSHIVVPR LFDHD QAYILQN P D G RIVF A IP YE D 269
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 264 E F SI IGTTDVEYKGDP KA V K I E E S EI N YL LN V Y N TH FKKQL SRD D I VWTYSGVRPLCDDESDS P QAITRDYTL DIH DENG 343
Cdd:PRK12266 270 D F TL IGTTDVEYKGDP AK V A I S E E EI D YL CK V V N RY FKKQL TPA D V VWTYSGVRPLCDDESDS A QAITRDYTL ELD DENG 349
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 344 K APLLSVFGGK L TTYRKLAEHALEKL T PY YQGI GPAWT KESV LPGG AIE GDR - D DY AA R LRRRYP F L T E S LAR HY AR T YG 422
Cdd:PRK12266 350 G APLLSVFGGK I TTYRKLAEHALEKL A PY LPQM GPAWT AGAP LPGG DFP GDR f D AL AA A LRRRYP W L P E A LAR RL AR A YG 429
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 16131300 423 SNS E L LLG N A GTVS DLGE D FGH EF YEAE LK YLV D HEW V R R A D D A LWRRTK Q G MW L N A D QQ S R VSQ WL VEYTQQRLSL A S 501
Cdd:PRK12266 430 TRA E R LLG G A TSLA DLGE H FGH GL YEAE VD YLV E HEW A R T A E D I LWRRTK L G LR L D A E QQ A R LEA WL AARRAAAAAA A A 508
Name
Accession
Description
Interval
E-value
glpD
PRK12266 glycerol-3-phosphate dehydrogenase; Reviewed
27-501
0e+00
glycerol-3-phosphate dehydrogenase; Reviewed
Pssm-ID: 237027 [Multi-domain]
Cd Length: 508
Bit Score: 960.37
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 27 LSVL ML E AQ DLA C ATSSAS S KLIHGGLRYLEHYEFRLV S EALAEREVLL K MAPHI AF PMRF R LPHRPHLRPAWMIR I GLF 106
Cdd:PRK12266 30 LSVL LC E QD DLA S ATSSAS T KLIHGGLRYLEHYEFRLV R EALAEREVLL R MAPHI IW PMRF V LPHRPHLRPAWMIR A GLF 109
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 107 M YDHLGKR T SLPGS T GL RF G --- A N S V LKPEI K RGFEYSDCWVDDARLV LA NA QMVVRK G G E V LTRTR AT SARRENGLW I 183
Cdd:PRK12266 110 L YDHLGKR K SLPGS R GL DL G rdp A G S P LKPEI T RGFEYSDCWVDDARLV VL NA RDAAER G A E I LTRTR VV SARRENGLW H 189
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 184 V EA ED ID TGK K Y SWQ AR G LVNA T GPWVKQF F DDG MH LPSPYGIRL I KGSHIVVPR VHTQK QAYILQN E D K RIVF V IP WM D 263
Cdd:PRK12266 190 V TL ED TA TGK R Y TVR AR A LVNA A GPWVKQF L DDG LG LPSPYGIRL V KGSHIVVPR LFDHD QAYILQN P D G RIVF A IP YE D 269
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 264 E F SI IGTTDVEYKGDP KA V K I E E S EI N YL LN V Y N TH FKKQL SRD D I VWTYSGVRPLCDDESDS P QAITRDYTL DIH DENG 343
Cdd:PRK12266 270 D F TL IGTTDVEYKGDP AK V A I S E E EI D YL CK V V N RY FKKQL TPA D V VWTYSGVRPLCDDESDS A QAITRDYTL ELD DENG 349
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 344 K APLLSVFGGK L TTYRKLAEHALEKL T PY YQGI GPAWT KESV LPGG AIE GDR - D DY AA R LRRRYP F L T E S LAR HY AR T YG 422
Cdd:PRK12266 350 G APLLSVFGGK I TTYRKLAEHALEKL A PY LPQM GPAWT AGAP LPGG DFP GDR f D AL AA A LRRRYP W L P E A LAR RL AR A YG 429
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 16131300 423 SNS E L LLG N A GTVS DLGE D FGH EF YEAE LK YLV D HEW V R R A D D A LWRRTK Q G MW L N A D QQ S R VSQ WL VEYTQQRLSL A S 501
Cdd:PRK12266 430 TRA E R LLG G A TSLA DLGE H FGH GL YEAE VD YLV E HEW A R T A E D I LWRRTK L G LR L D A E QQ A R LEA WL AARRAAAAAA A A 508
GlpA
COG0578 Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Glycerol-3-phosphate ...
27-497
0e+00
Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Glycerol-3-phosphate dehydrogenase is part of the Pathway/BioSystem: Isoprenoid biosynthesis
Pssm-ID: 440343 [Multi-domain]
Cd Length: 501
Bit Score: 607.90
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 27 LSV LML E AQ D L A CA TSS A SSKLIHGGLRYLE HY EFRLV S EAL A EREVLL KM APH IAF P MR F R LP HRP - HL RPAW M IR I GL 105
Cdd:COG0578 8 LSV ALV E KG D F A SG TSS R SSKLIHGGLRYLE QG EFRLV R EAL R EREVLL RN APH LVR P LP F L LP LYK g GE RPAW L IR A GL 87
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 106 F M YD H L GK R TS LP GSTG L RF ----- G A NSVLKPEIKR GFEY S D CW VDDARLVL AN A QMVVRK G GE VL TR TR A T SAR R EN G 180
Cdd:COG0578 88 F L YD L L AG R KG LP RHRR L SR aeala L A PLLRPDGLRG GFEY Y D AQ VDDARLVL EL A RTAAER G AV VL NY TR V T GLL R DG G 167
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 181 - L W I V EAE D ID TG KKYSWQ AR GL VNATGPWV KQFFDD g MHLPS P YGI R LI KGSH I VVPR VH -- TQKQA YI L QN E D K R I VF 257
Cdd:COG0578 168 r V W G V TVR D RL TG EEFTVR AR VV VNATGPWV DELRAL - DGPKA P RRV R PS KGSH L VVPR LF lp LDDAL YI F QN T D G R V VF 246
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 258 V IPW MD e FSI IGTTD VE Y K GDP KAVKIE E S EI N YLL NVY N TH F KKQ L S RDD I V W TY S GVRPL C DD ESDSPQ A IT RD YTLD 337
Cdd:COG0578 247 A IPW EG - RTL IGTTD TD Y D GDP DEPAAT E E EI D YLL EAA N RY F ARP L T RDD V V S TY A GVRPL L DD GGKDTS A LS RD HVIE 325
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 338 I hden G K A P LLS VF GGKLTTYRK L AE H A LEKLTPYY - QGIG P A WT KESV LPGG ai EGDR D DYA A R L r RRY P F L T E S LAR H 416
Cdd:COG0578 326 V ---- G P A G LLS IA GGKLTTYRK M AE D A VDAAARLL g LPRR P C WT ADLP LPGG -- DAGF D AFV A A L - AAA P G L P E A LAR R 398
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 417 YA R T YG SNS E LL L GN A GTVS DLGE DF G H -- EFY EAE LK Y L V D HE WV R RAD D A L W RRT KQ G M w L N AD QQSRVSQWLV E YTQ 494
Cdd:COG0578 399 LL R R YG TRA E EV L AL A AEDP DLGE PL G P gl PYL EAE VV Y A V R HE MA R TLE D V L L RRT RL G L - L D AD AAAAAAPAVA E LMA 477
...
gi 16131300 495 QR L 497
Cdd:COG0578 478 AE L 480
glycerol3P_ox_1
NF033461 type 1 glycerol-3-phosphate oxidase; Glycerol-3-phosphate oxidase, also called ...
27-471
5.05e-52
type 1 glycerol-3-phosphate oxidase; Glycerol-3-phosphate oxidase, also called alpha-glycerophosphate oxidase (GlpO), is an FAD-dependent enzyme related to the glycerol-3-phosphate dehydrogenase GlpD. Notably, GlpO releases hydrogen peroxide, which can contribute to virulence.
Pssm-ID: 411122 [Multi-domain]
Cd Length: 607
Bit Score: 185.92
E-value: 5.05e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 27 LSVLML E A QD L A CA TSS A S S KL I HGG L RYL EHYEFRL V SEALA ER E V LLKM APHI -- AF PM rfrlphrph L R P AW ----- 99
Cdd:NF033461 42 MKTGLI E M QD F A EG TSS R S T KL V HGG I RYL KTFDVEV V ADTVK ER A V VQGI APHI pk PD PM --------- L L P IY depga 112
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 100 --- M IRIGLF M -- YD H L G krtslp G S TG LRF g AN SV L -------- K P EI K R ----- G FE Y S D CWVD DARLV LA N AQMVVR 161
Cdd:NF033461 113 tfn M FSVKVA M dl YD Q L A ------ G V TG TKY - AN YT L tkeevler E P QL K K eglqg G GV Y L D FRNN DARLV IE N IKRAHE 185
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 162 K G GEVLT R TR A TS - ARR ENG LWI - V E AED ID TG KKYSWQ A RGLV N A TGPW VKQFFDDGMHLPSPYGI R LI KG S H I VV P R - 238
Cdd:NF033461 186 D G ALMAS R VK A VG f LHD ENG KIN g V K AED LL TG ETFDIH A KLVI N T TGPW SDKVRNLDKKEALVPQM R PT KG V H L VV D R s 265
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 239 --------- VH T Q K Q ayilqne D K R I VFVIP WMDE f SII GTTD VE Y K GD P K AVKIEESEIN YLL NVY N THF - KKQLSR DD 308
Cdd:NF033461 266 rlpvpqpty FD T G K N ------- D G R M VFVIP RENK - TYF GTTD TD Y T GD Y K HPTVTQEDVD YLL EIV N NRY p EANITI DD 337
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 309 I VWTYS G V RPL ---------------- CD DES ------------------------------------ DS P Q A IT R DYT L 336
Cdd:NF033461 338 I EASWA G L RPL isgnggsdynggnngk LS DES fdevidvvkdylndeasrddvekvlnnlesslseke LN P S A VS R GSS L 417
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 337 DI h D E N G kap L LSVF GGK L T T YRK L AE H AL EKLT ----- PYYQGIGPAWT K ESVLP GG A I EGDR - D DYAAR L RRR -- YPF 408
Cdd:NF033461 418 ER - A E D G --- L ITLA GGK I T D YRK M AE G AL KLIQ kilke EFNRSFELIDS K TYPVS GG E I DPTN v D EELEF L AKQ gv EKG 493
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 16131300 409 L T E SL A RHY A RT YGSN SELLLGNAGT V S ----- D L G E DFG hefyeae L K Y LV D H E W V RRAD D A L W RRT 471
Cdd:NF033461 494 L S E ED A LYL A NL YGSN APKVFALIDK V E paegl S L A E TLS ------- L H Y AL D E E M V LTPV D Y L L RRT 554
DAO
pfam01266 FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
5-321
2.80e-35
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.
Pssm-ID: 426168 [Multi-domain]
Cd Length: 339
Bit Score: 134.45
E-value: 2.80e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 5 D LI VIG ggingagiaada A G RGLSV LM LE AQ - D LACAT S SASSK LIH G GLRYLE HY E F - RL VS EAL AER E V L LKM - APHI 81
Cdd:pfam01266 1 D VV VIG ggivglstayel A R RGLSV TL LE RG d D PGSGA S GRNAG LIH P GLRYLE PS E L a RL AL EAL DLW E E L EEE l GIDC 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 82 A F PMRFR L PH - R PHLRP A WMIRIGLFM yd H LG KRTS L -- PGSTGLRFGAN svlk P EIKR G FE Y S D C - W VD D ARL VL A N A Q 157
Cdd:pfam01266 81 G F RRCGV L VL a R DEEEE A LEKLLAALR -- R LG VPAE L ld AEELRELEPLL ---- P GLRG G LF Y P D G g H VD P ARL LR A L A R 154
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 158 MVVRK G GEVLTR T RA T SARR E N G L W I V E aedi D TG kkysw Q A RGL VNA T G P W VKQFFDD G MH LP spyg I R LIK G SHI V VP 237
Cdd:pfam01266 155 AAEAL G VRIIEG T EV T GIEE E G G V W G V V ---- T TG ----- E A DAV VNA A G A W ADLLALP G LR LP ---- V R PVR G QVL V LE 221
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 238 RVHTQKQAY -- ILQNEDK R I V FVI P WM D EFSII G T TD V E YKG D P ka VKIEES EI NY LL NVYNTH F K kql SRD DI VWTYS G 315
Cdd:pfam01266 222 PLPEALLIL pv PITVDPG R G V YLR P RA D GRLLL G G TD E E DGF D D -- PTPDPE EI EE LL EAARRL F P --- ALA DI ERAWA G 296
....*.
gi 16131300 316 V RPL C D 321
Cdd:pfam01266 297 L RPL P D 302
Name
Accession
Description
Interval
E-value
glpD
PRK12266 glycerol-3-phosphate dehydrogenase; Reviewed
27-501
0e+00
glycerol-3-phosphate dehydrogenase; Reviewed
Pssm-ID: 237027 [Multi-domain]
Cd Length: 508
Bit Score: 960.37
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 27 LSVL ML E AQ DLA C ATSSAS S KLIHGGLRYLEHYEFRLV S EALAEREVLL K MAPHI AF PMRF R LPHRPHLRPAWMIR I GLF 106
Cdd:PRK12266 30 LSVL LC E QD DLA S ATSSAS T KLIHGGLRYLEHYEFRLV R EALAEREVLL R MAPHI IW PMRF V LPHRPHLRPAWMIR A GLF 109
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 107 M YDHLGKR T SLPGS T GL RF G --- A N S V LKPEI K RGFEYSDCWVDDARLV LA NA QMVVRK G G E V LTRTR AT SARRENGLW I 183
Cdd:PRK12266 110 L YDHLGKR K SLPGS R GL DL G rdp A G S P LKPEI T RGFEYSDCWVDDARLV VL NA RDAAER G A E I LTRTR VV SARRENGLW H 189
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 184 V EA ED ID TGK K Y SWQ AR G LVNA T GPWVKQF F DDG MH LPSPYGIRL I KGSHIVVPR VHTQK QAYILQN E D K RIVF V IP WM D 263
Cdd:PRK12266 190 V TL ED TA TGK R Y TVR AR A LVNA A GPWVKQF L DDG LG LPSPYGIRL V KGSHIVVPR LFDHD QAYILQN P D G RIVF A IP YE D 269
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 264 E F SI IGTTDVEYKGDP KA V K I E E S EI N YL LN V Y N TH FKKQL SRD D I VWTYSGVRPLCDDESDS P QAITRDYTL DIH DENG 343
Cdd:PRK12266 270 D F TL IGTTDVEYKGDP AK V A I S E E EI D YL CK V V N RY FKKQL TPA D V VWTYSGVRPLCDDESDS A QAITRDYTL ELD DENG 349
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 344 K APLLSVFGGK L TTYRKLAEHALEKL T PY YQGI GPAWT KESV LPGG AIE GDR - D DY AA R LRRRYP F L T E S LAR HY AR T YG 422
Cdd:PRK12266 350 G APLLSVFGGK I TTYRKLAEHALEKL A PY LPQM GPAWT AGAP LPGG DFP GDR f D AL AA A LRRRYP W L P E A LAR RL AR A YG 429
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 16131300 423 SNS E L LLG N A GTVS DLGE D FGH EF YEAE LK YLV D HEW V R R A D D A LWRRTK Q G MW L N A D QQ S R VSQ WL VEYTQQRLSL A S 501
Cdd:PRK12266 430 TRA E R LLG G A TSLA DLGE H FGH GL YEAE VD YLV E HEW A R T A E D I LWRRTK L G LR L D A E QQ A R LEA WL AARRAAAAAA A A 508
PRK13369
PRK13369 glycerol-3-phosphate dehydrogenase; Provisional
27-489
0e+00
glycerol-3-phosphate dehydrogenase; Provisional
Pssm-ID: 237365 [Multi-domain]
Cd Length: 502
Bit Score: 699.41
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 27 L S VL ML E AQ DLA CA TSS A S S KL I HGGLRYLE H YEFRLV S EAL A EREVLL KM APHI AF PMRF R LPH R P HL RPAW MI R I GLF 106
Cdd:PRK13369 30 L K VL LC E KD DLA QG TSS R S G KL V HGGLRYLE Y YEFRLV R EAL I EREVLL AA APHI IW PMRF V LPH S P ED RPAW LV R L GLF 109
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 107 M YDHLG K R TS LPG STG L RFG --- ANSV LKPE IKR GFEYSDCWVDDARLV LA NA QMVVRK G GEV LTRTR AT SARRE N GLW I 183
Cdd:PRK13369 110 L YDHLG G R KR LPG TRT L DLR rdp EGAP LKPE YTK GFEYSDCWVDDARLV VL NA LDAAER G ATI LTRTR CV SARRE G GLW R 189
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 184 VE AE D i DT G KKYSWQ AR G LVNA T GPWV KQFFDDGMHLP S PYGI RL I KGSHIVVP RVHTQK QAY IL QN E DKR IV F VI P WMD 263
Cdd:PRK13369 190 VE TR D - AD G ETRTVR AR A LVNA A GPWV TDVIHRVAGSN S SRNV RL V KGSHIVVP KFWDGA QAY LF QN P DKR VI F AN P YEG 268
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 264 E F SI IGTTD VE Y K GDP KA V KIE E S EI N YLL NVY N TH FK KQ L S R D D I V WTY SGVRPL C DD ESDS P Q A I TRDY TL D IHD E N G 343
Cdd:PRK13369 269 D F TL IGTTD IA Y E GDP ED V AAD E E EI D YLL DAA N RY FK EK L R R E D V V HSF SGVRPL F DD GAGN P S A V TRDY VF D LDA E T G 348
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 344 K APLLSVFGGK L TT Y RKLAEHALE K L T P YYQGI G PA WT KESV LPGG A I - EG D R D DY A AR LR R RYP F L TES LA RH YAR T YG 422
Cdd:PRK13369 349 G APLLSVFGGK I TT F RKLAEHALE R L K P FFPQM G GD WT AGAP LPGG D I a NA D F D TF A DD LR D RYP W L PRP LA HR YAR L YG 428
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 16131300 423 SNSELL LG N A GTVS DLG ED FG HEFY EAE LK YLV DH EW V R R A D D A LWRRTK Q G MW L N A DQQSRVSQ W L 489
Cdd:PRK13369 429 TRAKDV LG G A RSLE DLG RH FG GGLT EAE VR YLV AR EW A R T A E D I LWRRTK L G LH L S A AERAALAA W F 495
GlpA
COG0578 Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Glycerol-3-phosphate ...
27-497
0e+00
Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Glycerol-3-phosphate dehydrogenase is part of the Pathway/BioSystem: Isoprenoid biosynthesis
Pssm-ID: 440343 [Multi-domain]
Cd Length: 501
Bit Score: 607.90
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 27 LSV LML E AQ D L A CA TSS A SSKLIHGGLRYLE HY EFRLV S EAL A EREVLL KM APH IAF P MR F R LP HRP - HL RPAW M IR I GL 105
Cdd:COG0578 8 LSV ALV E KG D F A SG TSS R SSKLIHGGLRYLE QG EFRLV R EAL R EREVLL RN APH LVR P LP F L LP LYK g GE RPAW L IR A GL 87
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 106 F M YD H L GK R TS LP GSTG L RF ----- G A NSVLKPEIKR GFEY S D CW VDDARLVL AN A QMVVRK G GE VL TR TR A T SAR R EN G 180
Cdd:COG0578 88 F L YD L L AG R KG LP RHRR L SR aeala L A PLLRPDGLRG GFEY Y D AQ VDDARLVL EL A RTAAER G AV VL NY TR V T GLL R DG G 167
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 181 - L W I V EAE D ID TG KKYSWQ AR GL VNATGPWV KQFFDD g MHLPS P YGI R LI KGSH I VVPR VH -- TQKQA YI L QN E D K R I VF 257
Cdd:COG0578 168 r V W G V TVR D RL TG EEFTVR AR VV VNATGPWV DELRAL - DGPKA P RRV R PS KGSH L VVPR LF lp LDDAL YI F QN T D G R V VF 246
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 258 V IPW MD e FSI IGTTD VE Y K GDP KAVKIE E S EI N YLL NVY N TH F KKQ L S RDD I V W TY S GVRPL C DD ESDSPQ A IT RD YTLD 337
Cdd:COG0578 247 A IPW EG - RTL IGTTD TD Y D GDP DEPAAT E E EI D YLL EAA N RY F ARP L T RDD V V S TY A GVRPL L DD GGKDTS A LS RD HVIE 325
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 338 I hden G K A P LLS VF GGKLTTYRK L AE H A LEKLTPYY - QGIG P A WT KESV LPGG ai EGDR D DYA A R L r RRY P F L T E S LAR H 416
Cdd:COG0578 326 V ---- G P A G LLS IA GGKLTTYRK M AE D A VDAAARLL g LPRR P C WT ADLP LPGG -- DAGF D AFV A A L - AAA P G L P E A LAR R 398
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 417 YA R T YG SNS E LL L GN A GTVS DLGE DF G H -- EFY EAE LK Y L V D HE WV R RAD D A L W RRT KQ G M w L N AD QQSRVSQWLV E YTQ 494
Cdd:COG0578 399 LL R R YG TRA E EV L AL A AEDP DLGE PL G P gl PYL EAE VV Y A V R HE MA R TLE D V L L RRT RL G L - L D AD AAAAAAPAVA E LMA 477
...
gi 16131300 495 QR L 497
Cdd:COG0578 478 AE L 480
glycerol3P_ox_1
NF033461 type 1 glycerol-3-phosphate oxidase; Glycerol-3-phosphate oxidase, also called ...
27-471
5.05e-52
type 1 glycerol-3-phosphate oxidase; Glycerol-3-phosphate oxidase, also called alpha-glycerophosphate oxidase (GlpO), is an FAD-dependent enzyme related to the glycerol-3-phosphate dehydrogenase GlpD. Notably, GlpO releases hydrogen peroxide, which can contribute to virulence.
Pssm-ID: 411122 [Multi-domain]
Cd Length: 607
Bit Score: 185.92
E-value: 5.05e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 27 LSVLML E A QD L A CA TSS A S S KL I HGG L RYL EHYEFRL V SEALA ER E V LLKM APHI -- AF PM rfrlphrph L R P AW ----- 99
Cdd:NF033461 42 MKTGLI E M QD F A EG TSS R S T KL V HGG I RYL KTFDVEV V ADTVK ER A V VQGI APHI pk PD PM --------- L L P IY depga 112
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 100 --- M IRIGLF M -- YD H L G krtslp G S TG LRF g AN SV L -------- K P EI K R ----- G FE Y S D CWVD DARLV LA N AQMVVR 161
Cdd:NF033461 113 tfn M FSVKVA M dl YD Q L A ------ G V TG TKY - AN YT L tkeevler E P QL K K eglqg G GV Y L D FRNN DARLV IE N IKRAHE 185
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 162 K G GEVLT R TR A TS - ARR ENG LWI - V E AED ID TG KKYSWQ A RGLV N A TGPW VKQFFDDGMHLPSPYGI R LI KG S H I VV P R - 238
Cdd:NF033461 186 D G ALMAS R VK A VG f LHD ENG KIN g V K AED LL TG ETFDIH A KLVI N T TGPW SDKVRNLDKKEALVPQM R PT KG V H L VV D R s 265
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 239 --------- VH T Q K Q ayilqne D K R I VFVIP WMDE f SII GTTD VE Y K GD P K AVKIEESEIN YLL NVY N THF - KKQLSR DD 308
Cdd:NF033461 266 rlpvpqpty FD T G K N ------- D G R M VFVIP RENK - TYF GTTD TD Y T GD Y K HPTVTQEDVD YLL EIV N NRY p EANITI DD 337
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 309 I VWTYS G V RPL ---------------- CD DES ------------------------------------ DS P Q A IT R DYT L 336
Cdd:NF033461 338 I EASWA G L RPL isgnggsdynggnngk LS DES fdevidvvkdylndeasrddvekvlnnlesslseke LN P S A VS R GSS L 417
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 337 DI h D E N G kap L LSVF GGK L T T YRK L AE H AL EKLT ----- PYYQGIGPAWT K ESVLP GG A I EGDR - D DYAAR L RRR -- YPF 408
Cdd:NF033461 418 ER - A E D G --- L ITLA GGK I T D YRK M AE G AL KLIQ kilke EFNRSFELIDS K TYPVS GG E I DPTN v D EELEF L AKQ gv EKG 493
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 16131300 409 L T E SL A RHY A RT YGSN SELLLGNAGT V S ----- D L G E DFG hefyeae L K Y LV D H E W V RRAD D A L W RRT 471
Cdd:NF033461 494 L S E ED A LYL A NL YGSN APKVFALIDK V E paegl S L A E TLS ------- L H Y AL D E E M V LTPV D Y L L RRT 554
PLN02464
PLN02464 glycerol-3-phosphate dehydrogenase
27-491
7.85e-48
glycerol-3-phosphate dehydrogenase
Pssm-ID: 215257 [Multi-domain]
Cd Length: 627
Bit Score: 174.97
E-value: 7.85e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 27 L S V LML E AQ D LACA TSS A S S KLIHGG L RYLE HYE F ------- R LV SE AL A ER EV L LKM APH IAFP mrfrlph R P HLR P A - 98
Cdd:PLN02464 95 L R V GLV E RE D FSSG TSS R S T KLIHGG V RYLE KAV F qldygql K LV FH AL E ER KQ L IEN APH LCHA ------- L P IMT P C y 167
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 99 -------- W M iri GL FM YD HLGKRTS L PG S TGLRFGANSV L K P EI --------- K RGFE Y S D CWVD D A RL VL A N A QMVVR 161
Cdd:PLN02464 168 dwfevpyy W A --- GL KA YD LVAGPRL L HL S RYYSAKESLE L F P TL akkgkdgsl K GTVV Y Y D GQMN D S RL NV A L A CTAAL 244
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 162 K G GE VL TRTRAT S - ARR E NGLW IV E A -- E D ID TGK KYSWQ A RGL VNA T GP WVKQF -- FD DG MHL P S pyg I RLIK G S HIV V 236
Cdd:PLN02464 245 A G AA VL NYAEVV S l IKD E STGR IV G A rv R D NL TGK EFDVY A KVV VNA A GP FCDEV rk MA DG KAK P M --- I CPSS G V HIV L 321
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 237 P RVHTQKQAYIL -- QNE D K R I VF VI PW MDE f SII GTTD ---- VEYKGD P K avkie E S EI NYL L NVYNTHFKKQLS R D D IV 310
Cdd:PLN02464 322 P DYYSPEGMGLI vp KTK D G R V VF ML PW LGR - TVA GTTD sktp ITMLPE P H ----- E D EI QFI L DAISDYLNVKVR R S D VL 395
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 311 WTY SG V RPL CD D E S - D S PQA I T RD YTL d IHDEN G kap L LSVF GGK L TTYR KL AE H A LE ------ KL T P yyqg IGPAW T KE 383
Cdd:PLN02464 396 SAW SG I RPL AV D P S a K S TES I S RD HVV - CEEPD G --- L VTIT GGK W TTYR SM AE D A VD aaiksg KL S P ---- TNGCV T TD 467
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 384 SV L P G G ai EG DRDDYAAR L RRR Y PFLT ------------- ESL A R H Y A RT YG snselll G N A GT V SDLGED -------- F 442
Cdd:PLN02464 468 LP L V G A -- EG YEPSLFTQ L AQQ Y VRMK rtyggkvvpgamd TAA A K H L A HA YG ------- G R A DR V AEIAQN eglgkrla H 538
490 500 510 520
....*....|....*....|....*....|....*....|....*....
gi 16131300 443 G HE F Y EAE LK Y LVD HE WVRR A D D ALW RRT KQG m W L NA D QQS R VSQWL VE 491
Cdd:PLN02464 539 G YP F L EAE VA Y CAR HE YCES A V D FIA RRT RLA - F L DT D AAV R ALPRV VE 586
DAO
pfam01266 FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
5-321
2.80e-35
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.
Pssm-ID: 426168 [Multi-domain]
Cd Length: 339
Bit Score: 134.45
E-value: 2.80e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 5 D LI VIG ggingagiaada A G RGLSV LM LE AQ - D LACAT S SASSK LIH G GLRYLE HY E F - RL VS EAL AER E V L LKM - APHI 81
Cdd:pfam01266 1 D VV VIG ggivglstayel A R RGLSV TL LE RG d D PGSGA S GRNAG LIH P GLRYLE PS E L a RL AL EAL DLW E E L EEE l GIDC 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 82 A F PMRFR L PH - R PHLRP A WMIRIGLFM yd H LG KRTS L -- PGSTGLRFGAN svlk P EIKR G FE Y S D C - W VD D ARL VL A N A Q 157
Cdd:pfam01266 81 G F RRCGV L VL a R DEEEE A LEKLLAALR -- R LG VPAE L ld AEELRELEPLL ---- P GLRG G LF Y P D G g H VD P ARL LR A L A R 154
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 158 MVVRK G GEVLTR T RA T SARR E N G L W I V E aedi D TG kkysw Q A RGL VNA T G P W VKQFFDD G MH LP spyg I R LIK G SHI V VP 237
Cdd:pfam01266 155 AAEAL G VRIIEG T EV T GIEE E G G V W G V V ---- T TG ----- E A DAV VNA A G A W ADLLALP G LR LP ---- V R PVR G QVL V LE 221
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 238 RVHTQKQAY -- ILQNEDK R I V FVI P WM D EFSII G T TD V E YKG D P ka VKIEES EI NY LL NVYNTH F K kql SRD DI VWTYS G 315
Cdd:pfam01266 222 PLPEALLIL pv PITVDPG R G V YLR P RA D GRLLL G G TD E E DGF D D -- PTPDPE EI EE LL EAARRL F P --- ALA DI ERAWA G 296
....*.
gi 16131300 316 V RPL C D 321
Cdd:pfam01266 297 L RPL P D 302
DAO_C
pfam16901 C-terminal domain of alpha-glycerophosphate oxidase; DAO_C is the C-terminal region of ...
381-471
1.35e-12
C-terminal domain of alpha-glycerophosphate oxidase; DAO_C is the C-terminal region of alpha-glycerophosphate oxidase.
Pssm-ID: 465305 [Multi-domain]
Cd Length: 126
Bit Score: 64.48
E-value: 1.35e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 381 TK ESV L P G G ai E G DRDDY AARL RR RY P f L T E SL A R H Y AR T YGS NSELL L GN A GTVS D -- LGE -- DFGHEFY EAE LK Y L V D 456
Cdd:pfam16901 3 TK KLP L L G A -- D G YSANL AARL AQ RY G - L D E EV A E H L AR R YGS RADEV L EL A LADG D pe LGE rl SPAYPYI EAE VV Y A V R 79
90
....*....|....*
gi 16131300 457 HE WVRRAD D A L W RRT 471
Cdd:pfam16901 80 HE MALTLV D V L A RRT 94
glpA
PRK11101 anaerobic glycerol-3-phosphate dehydrogenase subunit A;
27-475
7.84e-12
anaerobic glycerol-3-phosphate dehydrogenase subunit A;
Pssm-ID: 236847 [Multi-domain]
Cd Length: 546
Bit Score: 67.35
E-value: 7.84e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 27 L SVLML E AQ D L A CATSSASSK L I H G G L RY LEH y EFRLVS E ALA E REV L LKM A P H IAF P MR frlphrphlrpawmiri GLF 106
Cdd:PRK11101 30 L RCILV E RH D I A TGATGRNHG L L H S G A RY AVT - DAESAR E CIS E NQI L KRI A R H CVE P TD ----------------- GLF 91
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 107 MY --- D H L GKRTSLPGSTG l RF G ANSV - LK P EIKRGF E YS ------------ D CW VD DA RL VL AN AQMVVRK G GEV LT RT 170
Cdd:PRK11101 92 IT lpe D D L AFQATFIRACE - EA G IEAE a ID P QQALIL E PA vnpaligavkvp D GT VD PF RL TA AN MLDAKEH G AQI LT YH 170
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 171 RA T SAR RE NGLWI - V EAE D ID TG KKYSWQ A RGL VNA T G P W --- VKQFF D DGMHLPSPY G IR LI KGSH I --- V VP R VHTQK 243
Cdd:PRK11101 171 EV T GLI RE GDTVC g V RVR D HL TG ETQEIH A PVV VNA A G I W gqh IAEYA D LRIRMFPAK G SL LI MDHR I nnh V IN R CRKPA 250
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 244 Q A Y IL qnedkrivfv I P W m D EF S I IGTT D -- VE Y - KG D PKA V KI EE SE I nyl L NVYNTHFKKQLSRDD I VWT Y S GVRPL C 320
Cdd:PRK11101 251 D A D IL ---------- V P G - D TI S L IGTT S tr ID Y d QI D DNR V TA EE VD I --- L LREGEKLAPVMAKTR I LRA Y A GVRPL V 316
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 321 DDES D - S PQAIT R DYT L DI H D E - N G KAPLLSVF GGKL T TYR KL AE H A LEKLTPYYQGIG P AW T KESV LPG G aiegdr DDY 398
Cdd:PRK11101 317 ASDD D p S GRNVS R GIV L LD H A E r D G LDGFITIT GGKL M TYR LM AE W A TDAVCRKLGNTR P CT T ADTP LPG S ------ QEP 390
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 399 A ARLR R RYPF L TES L A ----- RH YA R T ygsn SEL L LGNAGTV S DLG E dfghef Y EA ---- E LK Y L V DHEW V RRAD D a L W R 469
Cdd:PRK11101 391 A EVTL R KVIS L PAP L R gsavy RH GD R A ---- PAW L SEGRLDR S LVC E ------ C EA vtag E VR Y A V ENLN V NNLL D - L R R 459
....*.
gi 16131300 470 RT KQ GM 475
Cdd:PRK11101 460 RT RV GM 465
DadA
COG0665 Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
27-322
9.35e-12
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
Pssm-ID: 440429 [Multi-domain]
Cd Length: 364
Bit Score: 66.47
E-value: 9.35e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 27 L S V LM LE AQDLACAT S SASSKLIHG G lr YLEHYEFR LV SE A LAEREVLLKM A PHIAFPMR FR lp HRPH L RP A W ------ M 100
Cdd:COG0665 26 L D V TV LE RGRPGSGA S GRNAGQLRP G -- LAALADRA LV RL A REALDLWREL A AELGIDCD FR -- RTGV L YL A R teaela A 101
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 101 I R IGLFMYDH LG KRTS L PGSTG LR FGANSVLK P EIKR G FEYS D C - W VD D A R LV L A N A QMVVRK G GEVLTR T RA T SAR RE N 179
Cdd:COG0665 102 L R AEAEALRA LG LPVE L LDAAE LR EREPGLGS P DYAG G LYDP D D g H VD P A K LV R A L A RAARAA G VRIREG T PV T GLE RE G 181
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131300 180 G LWI - V EA E D idt G kky SWQ A RGL V N A T G P W VKQFFDD - G MH LP spyg I R LIK G SHI V VPRVHTQKQAYI L QNED kri V F 257
Cdd:COG0665 182 G RVT g V RT E R --- G --- TVR A DAV V L A A G A W SARLLPM l G LR LP ---- L R PVR G YVL V TEPLPDLPLRPV L DDTG --- V Y 248
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 16131300 258 VI P WM D EFSII G T T DVEYKG D P kav KIEESEINY LL NVYNTH F k KQ L SRDD IV WTYS G V RP LCD D 322
Cdd:COG0665 249 LR P TA D GRLLV G G T AEPAGF D R --- APTPERLEA LL RRLRRL F - PA L ADAE IV RAWA G L RP MTP D 309
CzcO
COG2072 Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
166-209
9.94e-03
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];
Pssm-ID: 441675 [Multi-domain]
Cd Length: 414
Bit Score: 38.31
E-value: 9.94e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 16131300 166 VLTR T RA TSAR -- REN G L W I V EAE D ID T gkkys WQ AR GL V N ATGP W 209
Cdd:COG2072 99 IRFG T EV TSAR wd EAD G R W T V TTD D GE T ----- LT AR FV V V ATGP L 139
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
