|
Name |
Accession |
Description |
Interval |
E-value |
| PRK15445 |
PRK15445 |
arsenical efflux pump membrane protein ArsB; |
2-428 |
0e+00 |
|
arsenical efflux pump membrane protein ArsB;
Pssm-ID: 185342 Cd Length: 427 Bit Score: 741.60 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 2 LLAGAIFVLTIVLVIWQPKGLGIGWSATLGAVLALVTGVVHPGDIPVVWNIVWNATAAFIAVIIISLLLDESGFFEWAAL 81
Cdd:PRK15445 1 LLAIAIFLLTLVLVIWQPKGLGIGWSALLGAVLALLTGVVSLGDVPVVWGIVWNATLTFIAIIIISLLLDEAGFFEWAAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 82 HVSRWGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSKGTTLAFVMAAGFIADTASLPLIVSNLVN 161
Cdd:PRK15445 81 HVARWAKGNGRKLFVYIVLLGAAVAALFANDGAALILTPIVLAMLLALGFSKKATLAFVMAAGFIADTASLPLVVSNLVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 162 IVSADFFGLGFREYASVMVPVDIAAIVATLVMLHLYFRKDIPQNYDMALLKSPAEAIKDPATFKTGWVVLLLLLVGFFVL 241
Cdd:PRK15445 161 IVSADYFGIGFAEYASVMVPVNLVSLAASLLVLWLYFRKDIPKTYDLELLKEPASAIKDPALFKLGWIVLALLLVGYFVL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 242 EPLGIPVSAIAAVGALILFVVAKRGHAINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNVLADNGLWAAT 321
Cdd:PRK15445 241 EPLGIPVSAIAGVGALILLLVARRGHAINTKKVLKGAPWQIVIFSLGMYLVVYGLRNAGLTDYLAGVLNYLADQGLFAAT 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 322 LGTGFLTAFLSSIMNNMPTVLVGALSIDGSTASGVIKEAMVYANVIGCDLGPKITPIGSLATLLWLHVLSQKNMTISWGY 401
Cdd:PRK15445 321 LGTGFLAAFLSSVMNNMPTVLIGALAIDGSNATGVIKEAMIYANVIGSDLGPKITPIGSLATLLWLHVLAQKGVKISWGY 400
|
410 420
....*....|....*....|....*..
gi 90111602 402 YFRTGIIMTLPVLFVTLAALALRLSFT 428
Cdd:PRK15445 401 YFKVGIIITLPVLLVTLLALALRLSLF 427
|
|
| 2a45 |
TIGR00935 |
arsenite/antimonite efflux pump membrane protein; Members of this protein family are ArsB, a ... |
3-427 |
0e+00 |
|
arsenite/antimonite efflux pump membrane protein; Members of this protein family are ArsB, a highly hydrophobic integral membrane protein involved in transport processes used to protect cells from arsenite (or antimonite). Members of the seed alignment were selected by adjacency to the ATPase subunit ArsA that energizes the transport. [Cellular processes, Detoxification, Transport and binding proteins, Other]
Pssm-ID: 213571 Cd Length: 426 Bit Score: 609.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 3 LAGAIFVLTIVLVIWQPKGLGIGWSATLGAVLALVTGVVHPGDIPVVWNIVWNATAAFIAVIIISLLLDESGFFEWAALH 82
Cdd:TIGR00935 2 LAVLIFLLTLVLVIWQPKGLGIGWSATIGAVLALLSGVVSFGDVPVVTGIVWNATLTFVAIIIISLILDEIGFFEWAALH 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 83 VSRWGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSKGTTLAFVMAAGFIADTASLPLIVSNLVNI 162
Cdd:TIGR00935 82 MARWAKGNGRKMFIYISLLGAIVAALFANDGAALILTPIVLAMVRALGFDEAAVLPFIMASGFIADTTSLPLIVSNLVNI 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 163 VSADFFGLGFREYASVMVPVDIAAIVATLVMLHLYFRKDIPQNYDMALLKSPAEAIKDPATFKTGWVVLLLLLVGFFVLE 242
Cdd:TIGR00935 162 VSADFFGIGFNEYAAVMIPPNIFALIASILVLYLYFRKDIPARYDVSQLREPKEAIKDQKLFKFSWVVLALLLVGYFGSE 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 243 PLGIPVSAIAAVGALILFVVAKRGHAINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNVLADNGLWAATL 322
Cdd:TIGR00935 242 FLNIPVSFVAATIALIFLVVAAKSHAVDTRKVIKGAPWNIVVFSLGMYLVVYGLRNVGLTDLLAGVLDYFADQGLFVATM 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 323 GTGFLTAFLSSIMNNMPTVLVGALSIDGSTASGVIKEAMVYANVIGCDLGPKITPIGSLATLLWLHVLSQKNMTISWGYY 402
Cdd:TIGR00935 322 GMGFLAAFLSSIMNNMPTVLINALSIDGSNATGVMKEAMIYANVIGSDLGPKITPIGSLATLLWLHVLAQKGVKISWGYY 401
|
410 420
....*....|....*....|....*
gi 90111602 403 FRTGIIMTLPVLFVTLAALALRLSF 427
Cdd:TIGR00935 402 FKVGIVITVPVLFITLAGLYLRLSI 426
|
|
| ArsB_permease |
cd01118 |
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in ... |
3-422 |
3.62e-165 |
|
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in eubacteria and archaea. A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump (ArsAB). The ArsAB complex is similar in many ways to ATP-binding cassette transporters, which have two groups of six transmembrane-spanning helical segments and two nucleotide-binding domains. The ArsB proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life.
Pssm-ID: 238538 [Multi-domain] Cd Length: 416 Bit Score: 470.59 E-value: 3.62e-165
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 3 LAGAIFVLTIVLVIWQPKGLGIGWSATLGAVLALVTGVVHPGDIPVVWNIVWNATAAFIAVIIISLLLDESGFFEWAALH 82
Cdd:cd01118 1 LAIAIFVLTLVLVIWRPFGLPEAVWAVLGAVIALILGLVSPHDALEVWGIVWDVTLTLIGVILLSLLLDEEGFFEWVAAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 83 VSRWGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSKGTTLAFVMAAGFIADTASLPLIVSNLVNI 162
Cdd:cd01118 81 AARWARGSGRKLFTLIVLLGAAVTAFFANDGTALILTPIVIALLRALGAKKNRTLPFLYACAFIADAASLPLPISNLVNI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 163 VSADFFGLGFREYASVMVPVDIAAIVATLVMLHLYFRKDIPQNYDMALLKSPAEAIKDPATFKTGWVVLLLLLVGFFVLE 242
Cdd:cd01118 161 VTAGYFGIGFTEYAALMFLPSIVSILATYVVLYLFFRRALPKRLETASVKKPSLAIKDPLLFGLAWTLLVLLVVSAFGVD 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 243 PLGIPVSAIAAVGALILFVVAKRGHAINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNVLADNGLWAATL 322
Cdd:cd01118 241 ILLIPPSFIAGVLALIFLLLARRGGAINPLKVLKEAPWGVLLFSLGLYVVVFGLKNAGLTAILADLLNWLVSQGLLAAIL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 323 GTGFLTAFLSSIMNNMPTVLVGALSIdgstASGVIKEAMVYANVIGCDLGPKITPIGSLATLLWLHVLSQKNMTISWGYY 402
Cdd:cd01118 321 GVGLLAAFLSNVMNNLPAVLIGALAL----AAGHAPEALVYANLIGVDLGPKLTPIGSLATLLWLHVLRRKGIRVSWGYY 396
|
410 420
....*....|....*....|
gi 90111602 403 FRTGIIMTLPVLFVTLAALA 422
Cdd:cd01118 397 LKVGLIVTPPVLVVTLAALI 416
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
1-425 |
3.42e-106 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 320.15 E-value: 3.42e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 1 MLLAGAIFVLTIVLVIWQPKGLGIGWSATLGAVLALVTGVVHPGDIPVVwnIVWNATAAFIAVIIISLLLDESGFFEWAA 80
Cdd:COG1055 2 MILALAIFVLTYLLIILEPRGLNRAVAALLGAALLLLLGVVSLEDALEA--IDWNTILFLLGMMIIVAILDESGFFEWLA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 81 LHVSRWGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSkgtTLAFVMAAGFIADTASLPLIVSNLV 160
Cdd:COG1055 80 IKLARRAKGSPRRLLWLLGLLTALLSAFLDNDTTALLLTPVVLAIARRLGLN---PVPFLIAIVFAANIGGAATPIGNPT 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 161 NIVSADFFGLGFREYASVMVPVDIAAIVATLVMLHLYFRKDIPQNYDMAllKSPAEAIKDPATFKTGWVVLLLLLVGFFV 240
Cdd:COG1055 157 NIMIASAGGLSFLDFLANLFPPSLVSLLVTLLVLYLLFRKELPAAPDLE--DDPKEAIKDRRLLRISLLVLALLLVGFVL 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 241 LEPLGIPVSAIAAVGALILFVVAKrghaINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNVLADNGLWAA 320
Cdd:COG1055 235 HSFLGLPPALIALLGAAVLLLLAR----VDVREVLKKVDWSTLLFFIGLFVVVGGLENTGLLDLLAELLASLTGGNLLLA 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 321 TLGTGFLTAFLSSIMNNMPTVLVGALSIDGSTASGvIKEAMVYANVIGCDLGPKITPIGSLATLLWLHVLSQKNMTISWG 400
Cdd:COG1055 311 ALLILWLSAILSAVVDNVPLVAALLPLIPDLGATG-NPEPLWLALALGATLGGNLTPIGSAANVIVLGIAEKKGIKISFG 389
|
410 420
....*....|....*....|....*
gi 90111602 401 YYFRTGIIMTLPVLFVTLAALALRL 425
Cdd:COG1055 390 EFLKVGLPLTLLTLLIALLYLLLLY 414
|
|
| ArsB |
pfam02040 |
Arsenical pump membrane protein; |
1-418 |
4.20e-86 |
|
Arsenical pump membrane protein;
Pssm-ID: 460426 Cd Length: 423 Bit Score: 269.16 E-value: 4.20e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 1 MLLAGAIFVLTIVLVIWQPKGLGIGWSATLGAVLALVTGVVHPGDIPVVWNIVWNATAAFIAVIIISLLLDESGFFEWAA 80
Cdd:pfam02040 4 FIFALFIFLLILQLKILQIGNLACGGAACAGAAGALIAGDVLFHDGITVNAILAFAAIAFIAIILDNIGFDEIAAFEMAA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 81 LHVSRWGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSKGTTLAFVMAAGFIADTASLPLIVSNLV 160
Cdd:pfam02040 84 AAKAKAAKGFGVRMFLGAILAAAFAAAGAALDGAAIILAMIRAAHFNAKHFFEFIIAPFFIADGFIADFTSLNFVNINLA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 161 NIVSADFFGLGFREYASVMVPVDIAAIVATLVMLHLYFRKDIPQNYDMALLKSPAEAIKDPATFKTGWVVLLLLLVGFFV 240
Cdd:pfam02040 164 DIFHADFFDIAFIDVAPRLFSLLAFIILASIFFLKLFFKKSDLKEVDKPEEAIKDEAIFDLNMFILGLLIIGLFAIEFFA 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 241 LEPLGIPVSAIAAVGALILFVVAKRGHAINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNVLADNGLWAA 320
Cdd:pfam02040 244 IEFFSIAGSIAAGFIAAAFKIAAQHSKAVHKEAPVAEAFFAIGFFSIGMGVRNAGLRDAGLDDILAAADQAAAAGGIFAG 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 321 TLGTGFLTAFLSSIMNNMPTVLVGALSIDGSTASGVIKEAMVYANVIGCDLGPKITPIGSLATLLWLHVLSQKNMTISWG 400
Cdd:pfam02040 324 FIAAGFIAAILNLIMNMIDALAIAALAIAGMDREALIRAALIGADLGGKDLGIGILAIGLLAHLLSHHGLKHKGGKIFKG 403
|
410
....*....|....*...
gi 90111602 401 YYFRTGIIMTLPVLFVTL 418
Cdd:pfam02040 404 GIFKTGIILLIPLLGITI 421
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK15445 |
PRK15445 |
arsenical efflux pump membrane protein ArsB; |
2-428 |
0e+00 |
|
arsenical efflux pump membrane protein ArsB;
Pssm-ID: 185342 Cd Length: 427 Bit Score: 741.60 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 2 LLAGAIFVLTIVLVIWQPKGLGIGWSATLGAVLALVTGVVHPGDIPVVWNIVWNATAAFIAVIIISLLLDESGFFEWAAL 81
Cdd:PRK15445 1 LLAIAIFLLTLVLVIWQPKGLGIGWSALLGAVLALLTGVVSLGDVPVVWGIVWNATLTFIAIIIISLLLDEAGFFEWAAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 82 HVSRWGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSKGTTLAFVMAAGFIADTASLPLIVSNLVN 161
Cdd:PRK15445 81 HVARWAKGNGRKLFVYIVLLGAAVAALFANDGAALILTPIVLAMLLALGFSKKATLAFVMAAGFIADTASLPLVVSNLVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 162 IVSADFFGLGFREYASVMVPVDIAAIVATLVMLHLYFRKDIPQNYDMALLKSPAEAIKDPATFKTGWVVLLLLLVGFFVL 241
Cdd:PRK15445 161 IVSADYFGIGFAEYASVMVPVNLVSLAASLLVLWLYFRKDIPKTYDLELLKEPASAIKDPALFKLGWIVLALLLVGYFVL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 242 EPLGIPVSAIAAVGALILFVVAKRGHAINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNVLADNGLWAAT 321
Cdd:PRK15445 241 EPLGIPVSAIAGVGALILLLVARRGHAINTKKVLKGAPWQIVIFSLGMYLVVYGLRNAGLTDYLAGVLNYLADQGLFAAT 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 322 LGTGFLTAFLSSIMNNMPTVLVGALSIDGSTASGVIKEAMVYANVIGCDLGPKITPIGSLATLLWLHVLSQKNMTISWGY 401
Cdd:PRK15445 321 LGTGFLAAFLSSVMNNMPTVLIGALAIDGSNATGVIKEAMIYANVIGSDLGPKITPIGSLATLLWLHVLAQKGVKISWGY 400
|
410 420
....*....|....*....|....*..
gi 90111602 402 YFRTGIIMTLPVLFVTLAALALRLSFT 428
Cdd:PRK15445 401 YFKVGIIITLPVLLVTLLALALRLSLF 427
|
|
| 2a45 |
TIGR00935 |
arsenite/antimonite efflux pump membrane protein; Members of this protein family are ArsB, a ... |
3-427 |
0e+00 |
|
arsenite/antimonite efflux pump membrane protein; Members of this protein family are ArsB, a highly hydrophobic integral membrane protein involved in transport processes used to protect cells from arsenite (or antimonite). Members of the seed alignment were selected by adjacency to the ATPase subunit ArsA that energizes the transport. [Cellular processes, Detoxification, Transport and binding proteins, Other]
Pssm-ID: 213571 Cd Length: 426 Bit Score: 609.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 3 LAGAIFVLTIVLVIWQPKGLGIGWSATLGAVLALVTGVVHPGDIPVVWNIVWNATAAFIAVIIISLLLDESGFFEWAALH 82
Cdd:TIGR00935 2 LAVLIFLLTLVLVIWQPKGLGIGWSATIGAVLALLSGVVSFGDVPVVTGIVWNATLTFVAIIIISLILDEIGFFEWAALH 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 83 VSRWGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSKGTTLAFVMAAGFIADTASLPLIVSNLVNI 162
Cdd:TIGR00935 82 MARWAKGNGRKMFIYISLLGAIVAALFANDGAALILTPIVLAMVRALGFDEAAVLPFIMASGFIADTTSLPLIVSNLVNI 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 163 VSADFFGLGFREYASVMVPVDIAAIVATLVMLHLYFRKDIPQNYDMALLKSPAEAIKDPATFKTGWVVLLLLLVGFFVLE 242
Cdd:TIGR00935 162 VSADFFGIGFNEYAAVMIPPNIFALIASILVLYLYFRKDIPARYDVSQLREPKEAIKDQKLFKFSWVVLALLLVGYFGSE 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 243 PLGIPVSAIAAVGALILFVVAKRGHAINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNVLADNGLWAATL 322
Cdd:TIGR00935 242 FLNIPVSFVAATIALIFLVVAAKSHAVDTRKVIKGAPWNIVVFSLGMYLVVYGLRNVGLTDLLAGVLDYFADQGLFVATM 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 323 GTGFLTAFLSSIMNNMPTVLVGALSIDGSTASGVIKEAMVYANVIGCDLGPKITPIGSLATLLWLHVLSQKNMTISWGYY 402
Cdd:TIGR00935 322 GMGFLAAFLSSIMNNMPTVLINALSIDGSNATGVMKEAMIYANVIGSDLGPKITPIGSLATLLWLHVLAQKGVKISWGYY 401
|
410 420
....*....|....*....|....*
gi 90111602 403 FRTGIIMTLPVLFVTLAALALRLSF 427
Cdd:TIGR00935 402 FKVGIVITVPVLFITLAGLYLRLSI 426
|
|
| ArsB_permease |
cd01118 |
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in ... |
3-422 |
3.62e-165 |
|
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in eubacteria and archaea. A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump (ArsAB). The ArsAB complex is similar in many ways to ATP-binding cassette transporters, which have two groups of six transmembrane-spanning helical segments and two nucleotide-binding domains. The ArsB proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life.
Pssm-ID: 238538 [Multi-domain] Cd Length: 416 Bit Score: 470.59 E-value: 3.62e-165
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 3 LAGAIFVLTIVLVIWQPKGLGIGWSATLGAVLALVTGVVHPGDIPVVWNIVWNATAAFIAVIIISLLLDESGFFEWAALH 82
Cdd:cd01118 1 LAIAIFVLTLVLVIWRPFGLPEAVWAVLGAVIALILGLVSPHDALEVWGIVWDVTLTLIGVILLSLLLDEEGFFEWVAAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 83 VSRWGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSKGTTLAFVMAAGFIADTASLPLIVSNLVNI 162
Cdd:cd01118 81 AARWARGSGRKLFTLIVLLGAAVTAFFANDGTALILTPIVIALLRALGAKKNRTLPFLYACAFIADAASLPLPISNLVNI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 163 VSADFFGLGFREYASVMVPVDIAAIVATLVMLHLYFRKDIPQNYDMALLKSPAEAIKDPATFKTGWVVLLLLLVGFFVLE 242
Cdd:cd01118 161 VTAGYFGIGFTEYAALMFLPSIVSILATYVVLYLFFRRALPKRLETASVKKPSLAIKDPLLFGLAWTLLVLLVVSAFGVD 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 243 PLGIPVSAIAAVGALILFVVAKRGHAINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNVLADNGLWAATL 322
Cdd:cd01118 241 ILLIPPSFIAGVLALIFLLLARRGGAINPLKVLKEAPWGVLLFSLGLYVVVFGLKNAGLTAILADLLNWLVSQGLLAAIL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 323 GTGFLTAFLSSIMNNMPTVLVGALSIdgstASGVIKEAMVYANVIGCDLGPKITPIGSLATLLWLHVLSQKNMTISWGYY 402
Cdd:cd01118 321 GVGLLAAFLSNVMNNLPAVLIGALAL----AAGHAPEALVYANLIGVDLGPKLTPIGSLATLLWLHVLRRKGIRVSWGYY 396
|
410 420
....*....|....*....|
gi 90111602 403 FRTGIIMTLPVLFVTLAALA 422
Cdd:cd01118 397 LKVGLIVTPPVLVVTLAALI 416
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
1-425 |
3.42e-106 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 320.15 E-value: 3.42e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 1 MLLAGAIFVLTIVLVIWQPKGLGIGWSATLGAVLALVTGVVHPGDIPVVwnIVWNATAAFIAVIIISLLLDESGFFEWAA 80
Cdd:COG1055 2 MILALAIFVLTYLLIILEPRGLNRAVAALLGAALLLLLGVVSLEDALEA--IDWNTILFLLGMMIIVAILDESGFFEWLA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 81 LHVSRWGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSkgtTLAFVMAAGFIADTASLPLIVSNLV 160
Cdd:COG1055 80 IKLARRAKGSPRRLLWLLGLLTALLSAFLDNDTTALLLTPVVLAIARRLGLN---PVPFLIAIVFAANIGGAATPIGNPT 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 161 NIVSADFFGLGFREYASVMVPVDIAAIVATLVMLHLYFRKDIPQNYDMAllKSPAEAIKDPATFKTGWVVLLLLLVGFFV 240
Cdd:COG1055 157 NIMIASAGGLSFLDFLANLFPPSLVSLLVTLLVLYLLFRKELPAAPDLE--DDPKEAIKDRRLLRISLLVLALLLVGFVL 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 241 LEPLGIPVSAIAAVGALILFVVAKrghaINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNVLADNGLWAA 320
Cdd:COG1055 235 HSFLGLPPALIALLGAAVLLLLAR----VDVREVLKKVDWSTLLFFIGLFVVVGGLENTGLLDLLAELLASLTGGNLLLA 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 321 TLGTGFLTAFLSSIMNNMPTVLVGALSIDGSTASGvIKEAMVYANVIGCDLGPKITPIGSLATLLWLHVLSQKNMTISWG 400
Cdd:COG1055 311 ALLILWLSAILSAVVDNVPLVAALLPLIPDLGATG-NPEPLWLALALGATLGGNLTPIGSAANVIVLGIAEKKGIKISFG 389
|
410 420
....*....|....*....|....*
gi 90111602 401 YYFRTGIIMTLPVLFVTLAALALRL 425
Cdd:COG1055 390 EFLKVGLPLTLLTLLIALLYLLLLY 414
|
|
| ArsB |
pfam02040 |
Arsenical pump membrane protein; |
1-418 |
4.20e-86 |
|
Arsenical pump membrane protein;
Pssm-ID: 460426 Cd Length: 423 Bit Score: 269.16 E-value: 4.20e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 1 MLLAGAIFVLTIVLVIWQPKGLGIGWSATLGAVLALVTGVVHPGDIPVVWNIVWNATAAFIAVIIISLLLDESGFFEWAA 80
Cdd:pfam02040 4 FIFALFIFLLILQLKILQIGNLACGGAACAGAAGALIAGDVLFHDGITVNAILAFAAIAFIAIILDNIGFDEIAAFEMAA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 81 LHVSRWGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSKGTTLAFVMAAGFIADTASLPLIVSNLV 160
Cdd:pfam02040 84 AAKAKAAKGFGVRMFLGAILAAAFAAAGAALDGAAIILAMIRAAHFNAKHFFEFIIAPFFIADGFIADFTSLNFVNINLA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 161 NIVSADFFGLGFREYASVMVPVDIAAIVATLVMLHLYFRKDIPQNYDMALLKSPAEAIKDPATFKTGWVVLLLLLVGFFV 240
Cdd:pfam02040 164 DIFHADFFDIAFIDVAPRLFSLLAFIILASIFFLKLFFKKSDLKEVDKPEEAIKDEAIFDLNMFILGLLIIGLFAIEFFA 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 241 LEPLGIPVSAIAAVGALILFVVAKRGHAINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNVLADNGLWAA 320
Cdd:pfam02040 244 IEFFSIAGSIAAGFIAAAFKIAAQHSKAVHKEAPVAEAFFAIGFFSIGMGVRNAGLRDAGLDDILAAADQAAAAGGIFAG 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 321 TLGTGFLTAFLSSIMNNMPTVLVGALSIDGSTASGVIKEAMVYANVIGCDLGPKITPIGSLATLLWLHVLSQKNMTISWG 400
Cdd:pfam02040 324 FIAAGFIAAILNLIMNMIDALAIAALAIAGMDREALIRAALIGADLGGKDLGIGILAIGLLAHLLSHHGLKHKGGKIFKG 403
|
410
....*....|....*...
gi 90111602 401 YYFRTGIIMTLPVLFVTL 418
Cdd:pfam02040 404 GIFKTGIILLIPLLGITI 421
|
|
| ArsB_NhaD_permease |
cd00625 |
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ... |
14-421 |
2.47e-67 |
|
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain] Cd Length: 396 Bit Score: 219.43 E-value: 2.47e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 14 LVIWQPKGLGIGWSATLGAVLALVTGVVHPGDIPVVwnIVWNATAAFIAVIIISLLLDESGFFEWAALHVSRWGNGRGRL 93
Cdd:cd00625 1 YVLIRPEKLPRAVVALLGAVLLVLLGVVSPKEALSA--IDWETILLLFGMMILSAALEETGLFDRLAAKLARASKGSRRL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 94 LFtWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSKgtTLAFVMAAGFIADTASLPLIVSNLVNIVSADFFGLGFR 173
Cdd:cd00625 79 LL-LLMLLTAALSAFFSNDATAVLLTPIVLALLRKLGLSP--PVPLLLALAFAANIGGAATPIGNPPNLIIASLSGLGFL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 174 EYASVMVPVDIAAIVATLVMLHLYFRKDIPQNYDMALLKSPAEAIKDPATFKTGWVVLLLLLVGFFVLEpLGIPVSAIAA 253
Cdd:cd00625 156 DFLAFMAPPALGLLLLLLGLLYLLFRKKLLLPDEDKLTVLAEPLPARPLLKKFLLLALLLLLLFVLLFF-FLIPLGLIAL 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 254 VGALILFVVAKRGhaINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNVLADNGLWAATLGTGFLTAFLSS 333
Cdd:cd00625 235 LGALLLLLLLVRG--LDPEEVLKSVDWGTLLFFAGLFVLVGALESTGLLEWLAELLVALVGLPPLAALLLIGLLSALLSN 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 334 IMNNMPTVLVGALSIdgstASGVIKEAMVYANVIGCDLGPKITPIGSLATLLWLHVLSQKNMTISWGYYFRTGIIMTLPV 413
Cdd:cd00625 313 FISNVPTVALLLPIA----ASLAPPEPAWLALALGSTLGGNLTLIGSLANLIPLGAAENAGVGISFGEFLKVGLPLTLLS 388
|
....*...
gi 90111602 414 LFVTLAAL 421
Cdd:cd00625 389 LVVSLLYL 396
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
12-364 |
1.04e-37 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 139.75 E-value: 1.04e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 12 IVLVIWQPkgLGIGWSATLGAVLALVTGVVHPGDIpvVWNIVWNATAAFIAVIIISLLLDESGFFEWAALHVSRWGNGRG 91
Cdd:pfam03600 1 YVLIITEK--LPRDVVALLGAVLLVLLGVLTPEEA--LSGIDSPTILLLLGMMIIGAILERTGLFDRLALKLLRLAGGKP 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 92 RLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSkgtTLAFVMAAGFIADTASLPLIVSNLVNIVSADFFGLG 171
Cdd:pfam03600 77 RRLLVALMLATALLSAFLSNDGTVLIMIPIVLALARRLGLP---PSPLLIALAFAANIGGTATPIGDPPNIIIASALGLS 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 172 FREYASVMVPVDIAAIVAT-LVMLHLYFRKDIPQNYDMALLKSPAE--AIKDPATFKTGWVVLLLLLVGFFVLEPLGIPV 248
Cdd:pfam03600 154 FGDFGFFMFPPVGVALLLVgLLPLLLIFRKLLPVRKEEEAELEELRkrAIKDKLLLAISALVLALVILGFLLLSVLALAG 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 249 SAIAAVgalilfvvakrGHAINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNVLAdnGLWAATLGTGFLT 328
Cdd:pfam03600 234 ALLLLL-----------TGVLDPEEALKAVDWSTLLFFAGLFILVGALEKTGLADALADALGGLS--GLLVALALILWLS 300
|
330 340 350
....*....|....*....|....*....|....*.
gi 90111602 329 AFLSSIMNNMPTVLVGALSIDGSTASGVIKEAMVYA 364
Cdd:pfam03600 301 ALLSAFISNVPTAALMAPIIVGMAPAAGLGDPDPLA 336
|
|
| P_permease |
cd01116 |
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible ... |
8-425 |
5.05e-26 |
|
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible for classic phenotype of oculocutaneous albinism type 2 (OCA2). Although the precise function of the P protein is unknown, it was predicted to regulate the intraorganelle pH, together with the ATP-driven proton pump. It shows significant sequence similarity to the Na+/H+ antiporter NhaD from Vibrio parahaemolyticus. Both proteins belong to ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease contains 8-13 transmembrane domains.
Pssm-ID: 238536 [Multi-domain] Cd Length: 413 Bit Score: 108.88 E-value: 5.05e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 8 FVLTIVLVIWQPKGLGIgwSATLGAVLALVTGVVHPGDIP--VVWNIVWNATAAFIAVIIISLLLDESGFFEWAALHVSR 85
Cdd:cd01116 1 FIITYALIIFEKVHRTV--AALAGALWLVILGLATLSPDLetIVSWVDWETLALLLGMMIIVSILSETGVFEYLAIWAVK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 86 WGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGfskGTTLAFVMAAGFIADTASLPLIVSNLVNIVSA 165
Cdd:cd01116 79 ISKGRPWRLLLLLGLLTAFLSAFLDNVTTVLLMVPVTIRLCEVLG---LNPVPVLISEVIAANIGGAATLIGDPPNIMIG 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 166 DFFGLGFREYASVMVPVDIAAIVATLVMLHLYFRKDIPQNYDMALLKS---PAEAIKDPATFKTGWVVLLLLLVGFFVLE 242
Cdd:cd01116 156 SAAGLTFNDFLLHMLPSVVLALVVTFILLYFLYRNILKAREEDVLALAelePKYPIKDKVLLLKSLTILTLVIIGFVLHS 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 243 PLGIPVSAIAAVGALILFVVAKRGHAINtgkVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNVLADNGLWAATL 322
Cdd:cd01116 236 PLGVSLGWIALLGALLLLLLADKLDFED---VLSRVEWDTLLFFAGLFVLVGGLEELGIIEWIAELLVGVILGRIAVAVI 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 323 GTGFLTAFLSSIMNNMPTVLVGA-LSIDGSTASGVIKEAMVYANVIGCDLGPKITPIGSLATLLWLHVLSQKNMTISWGY 401
Cdd:cd01116 313 LILWISALLSAFIDNIPVTATMIpIVKDLASQLGIPLLPLWWALALGACLGGNGTLIGASANVVAAGIAEQHGYKISFWE 392
|
410 420
....*....|....*....|....
gi 90111602 402 YFRTGiimtLPVLFVTLAALALRL 425
Cdd:cd01116 393 FLKVG----FPIMLVSLILATVYL 412
|
|
| YbiR_permease |
cd01117 |
Putative anion permease YbiR. Based on sequence similarity, YbiR proteins are predicted to ... |
27-421 |
1.93e-19 |
|
Putative anion permease YbiR. Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate sodium, sulfate, arsenite and organic anions. A typical ArsB/NhaD permease is composed of 8-13 transmembrane domains.
Pssm-ID: 238537 [Multi-domain] Cd Length: 384 Bit Score: 89.26 E-value: 1.93e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 27 SATLGAVLALVTGVVHPGDIPVVwnIVWNATAAFIAVIIISLLLDESGFFEWAALHVSRWGNGRGRLLFTwIVLLGAAVA 106
Cdd:cd01117 16 IALLGAALMLLFGVISLEDAPAA--IDLDTIILLFGLMVVSAALELSGFFDALGSRILVKAGSPRRLLFL-LVLLSGILS 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 107 ALFANDGAALILTPIVIAMLLALGFSkgtTLAFVMAAGFIADTASLPLIVSNLVNIVSADFFGLGFREYASVMVPVDIAA 186
Cdd:cd01117 93 ALLTNDTACLVFTPIVLELARVAGLP---PIPLLLALATAANIGSAATPIGNPQNLLIASESGISFPFFLAAMAPLALLG 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 187 IVATLVMLHLYFRKDiPQNYDMALLKSPAEAIKDPATFKTGWVVLLLLLVGFFVLEPLGIPVSAIAAVGALILFVVAKRg 266
Cdd:cd01117 170 LLLLLILLLVLFPGE-LKGLPLDKATKEEGVGARKLAVKLLVLILLLLVAFLALLGVIPLWTAALVAAVLLLLTRLKPR- 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 267 haintgKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNVLADnglwaaTLGTGFLTAFLSSIMNNMPTVLVGAL 346
Cdd:cd01117 248 ------RVLKKVDWGLLLFFAGLFILVGGFAQGLPLEGLSRLLPLLDS------VLSLFLVSIGLSQLISNVPAVLLLLP 315
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 90111602 347 SIDGSTASGVIKEAMvyanviGCDLGPKITPIGSLATLLWLHVLSQKNMTISWGYYFRTGIIMTLPVLFVTLAAL 421
Cdd:cd01117 316 FLPSADEKDWLLLAA------GSTIAGNLTLLGSAANLIVAEAAERRGVRLSFGEFLKYGVPLTLLTAAIGILWL 384
|
|
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
61-423 |
2.78e-11 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 64.79 E-value: 2.78e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 61 IAVIIISLLLDESGFFEWAALHVSRWGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSKGTTLA-- 138
Cdd:COG0471 1 LGGFVLAAALEKTGLGRRIALLLLKRFGGSPLRLLLGLMLATALLSAFISNTARAAMMLPIALSIAAALGSEKRSKFGsa 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 139 FVMAAGFIADTASLPLIVSNLVNIVSADFF------GLGFREYASVMVPVDIAAIVATLVMLHLYFRKDIPQNYDMALLK 212
Cdd:COG0471 81 LLLPIAFAASIGGMGTLIGTPPNLIAAGLLeeatgiPISFFEWMLVGLPVALVGLLLLWLVLYRLLPPEIKEVPGSKEVI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 213 SPAEAIKDPATF--KTGWVVLLLLLVGFFVLEPLGIPVSAIAAVGALILFVVakrgHAINTGKVLRGAPWQIVIFSLGMY 290
Cdd:COG0471 161 REELAELGPLSRreKIALAIFALTVLLWITGSLHGIPIAVVALLGAVLLLLT----GVLTWKDAYKSIPWGVLLLFGGGL 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 291 LVVYGLRNAGLTEYLSG-VLNVLADNGLWAATLGTGFLTAFLSSIMNNMPTV-LVGALSIDGSTASGVIKEAMVYANVIG 368
Cdd:COG0471 237 ALGAALEKTGLAAWLADaLLPLLGGLSPLLLLLLLALLTLLLTEFASNTATAaLLLPIAISLAQALGVNPLPLALAVAFA 316
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 90111602 369 CDLGPkITPIGSLATLLwlhVLSQKNMTIswGYYFRTGIIMTLPVLFVTLAALAL 423
Cdd:COG0471 317 ASCAF-LLPVGTPPNAI---VYGSGYYKF--KDFLKVGLPLNLIGLVVLLLLGPL 365
|
|
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
3-199 |
2.39e-10 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 61.71 E-value: 2.39e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 3 LAGAIFVLTIVLVIWQP-KGLGIGWSATLGAVLALVTGVVHPGDI--PVVWNIVWnataAFIAVIIISLLLDESGFFEWA 79
Cdd:COG0471 176 IALAIFALTVLLWITGSlHGIPIAVVALLGAVLLLLTGVLTWKDAykSIPWGVLL----LFGGGLALGAALEKTGLAAWL 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 80 ALHVSRWGNGRGRLLFTWIVLLGAAVAALFANDGA-ALILTPIVIAMLLALGFSkgtTLAFVMAAGFIADTASLpLIVSN 158
Cdd:COG0471 252 ADALLPLLGGLSPLLLLLLLALLTLLLTEFASNTAtAALLLPIAISLAQALGVN---PLPLALAVAFAASCAFL-LPVGT 327
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 90111602 159 LVNIVSADFFGLGFREYASVMVPVDIAAIVATLVMLHLYFR 199
Cdd:COG0471 328 PPNAIVYGSGYYKFKDFLKVGLPLNLIGLVVLLLLGPLWWP 368
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
6-423 |
1.56e-07 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 52.97 E-value: 1.56e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 6 AIFVLTIVLVIWQPKGLGIgwSATLGAVLALVTGVVHPGDIPVvwNIVWNATAAFIAVIIISLLLDESGFFEWAALHVSR 85
Cdd:cd01115 2 AILVFAAVLFVTEALPLDV--TALLVPVLLVLLGVVPPKEAFS--GFSDPAVILFLAGFILGAALTRTGLAKRIATKLLK 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 86 WGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSKGTTLAFVMAAGFIADTASLpliVSNLVNIVSA 165
Cdd:cd01115 78 RAGKGERRLLLLLMLVTAFLSAFMSNTATVAIMLPVALGLAAKLDISPSRLLMPLAFAASIGGMLTL---IGTPPNLVAS 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 166 DFFGLGFREYASVMVPVDIAAIVATLVMLHLYFrkdipqnydmallkspaeaikdpaTFKTGWVVLLLLLVGFFVLEPLG 245
Cdd:cd01115 155 GYLESLGGQGFSFFEFTPIGLPLLIIGLLYLWF------------------------IFRLAVLIITIVLLAALAAITGL 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 246 IPVSAIAAVGALILFVvakrGHAINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNVLADN-GLWAATLGT 324
Cdd:cd01115 211 LPVSVAIAIGAIVLVF----GGVLLTKEDYKSIDWGIIFLFAGGIPLGKALESSGAAALIAEALISLLGGlPPFAILLLL 286
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 325 GFLTAFLSSIMNNMPTVLVGA-LSIDGSTASGVIKEAMVYANVIGCDLgPKITPIGSLATLLwlhVLSQKNmtISWGYYF 403
Cdd:cd01115 287 CLLTLVLTNFISNTATAVLLApIALSIALSLGLPPEALLLAVAIGASC-AFMLPVGTPPNAI---VLGPGG--YKFSDFA 360
|
410 420
....*....|....*....|
gi 90111602 404 RTGIIMTLPVLFVTLAALAL 423
Cdd:cd01115 361 KVGLPLSILSLVVSVTMIPL 380
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
1-198 |
6.73e-04 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 41.80 E-value: 6.73e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 1 MLLAGAIFVLTIVLVIWQPKGLGIGWSATLGAVLALVTGVVHPGDIP---VVWNIVWNATAAFIAVIIISLLLDESGFFE 77
Cdd:cd01115 185 LWFIFRLAVLIITIVLLAALAAITGLLPVSVAIAIGAIVLVFGGVLLtkeDYKSIDWGIIFLFAGGIPLGKALESSGAAA 264
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 78 WAALHVSRWGNGRGRLLFTWIVLLGAAVAALF-ANDGAALILTPIVIAMLLALGFSKgttLAFVMAAGFIADTASLpLIV 156
Cdd:cd01115 265 LIAEALISLLGGLPPFAILLLLCLLTLVLTNFiSNTATAVLLAPIALSIALSLGLPP---EALLLAVAIGASCAFM-LPV 340
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 90111602 157 SNLVNIVSADFFGLGFREYASVMVPVDIAAIVATLVMLHLYF 198
Cdd:cd01115 341 GTPPNAIVLGPGGYKFSDFAKVGLPLSILSLVVSVTMIPLIW 382
|
|
| PLN00136 |
PLN00136 |
silicon transporter; Provisional |
28-220 |
2.70e-03 |
|
silicon transporter; Provisional
Pssm-ID: 215070 [Multi-domain] Cd Length: 482 Bit Score: 39.98 E-value: 2.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 28 ATLGAVLALVTGVVHPGDipVVWNIVWNATAAFIAVIIISLLLDESGFFEwaalHVSR---WGNGRGRLLFTWIVLLGAA 104
Cdd:PLN00136 39 ALLSAVLMIVFHVISPDD--AYASIDLPILGLLFATMVVGSYLKNAGMFK----HLGRllaWRSQGGRDLLCRVCVVTAL 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111602 105 VAALFANDGAALILTPIVIAMLLALGFSKGttlAFVMAAGFIADTASLPLIVSNLVNIVSADFFGLGFREYASVMVPVDI 184
Cdd:PLN00136 113 ASALFTNDTCCVVLTEFVLELAAERNLPAK---PFLLALASSANIGSSATPIGNPQNLVIAFNSKITFPKFLLGILPAML 189
|
170 180 190
....*....|....*....|....*....|....*.
gi 90111602 185 AAIVATLVMLHLYFRKDIPQNYDMALLKSPAEAIKD 220
Cdd:PLN00136 190 AGMAVNMVMLLCMYWKDLDGGAELSVDGKQMEAVEE 225
|
|
| |
