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Conserved domains on  [gi|90111691|ref|NP_418564|]
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protein FxsA [Escherichia coli str. K-12 substr. MG1655]

Protein Classification

FxsA family protein( domain architecture ID 10013808)

FxsA family protein similar to Escherichia coli exclusion protein FxsA, which acts as phage T7 F exclusion suppressor

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
fxsA PRK11463
phage T7 F exclusion suppressor FxsA; Reviewed
3-149 1.17e-37

phage T7 F exclusion suppressor FxsA; Reviewed


:

Pssm-ID: 236913  Cd Length: 148  Bit Score: 125.74  E-value: 1.17e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111691    3 WLPFIAIFL-YVYIEISIFIQVAHVLGVLLTLVLVIFTSVIGMSLVRNQGFKNFVLMQQKMAAGENPAAEMIKSVSLIIA 81
Cdd:PRK11463   1 MRPFLLLFLlYPLIEIAVFIAVASVIGVGWTLLLVILTSVLGVLLARSQGFKTLLRAQRKLARGELPAAELLDGLLLAVA 80
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 90111691   82 GLLLLLPGFFTDFLGLLLLLPPVQKHLTVKLMPHLRFSRMPGGGFSAGTGGGNTFDGEYQRKDDERDR 149
Cdd:PRK11463  81 GVLLLLPGFVTDILGLLLLLPPTRALLRPKLMKRLRRKRNFNGGFSAPGGGGDVIDGEYERKDDPDDR 148
 
Name Accession Description Interval E-value
fxsA PRK11463
phage T7 F exclusion suppressor FxsA; Reviewed
3-149 1.17e-37

phage T7 F exclusion suppressor FxsA; Reviewed


Pssm-ID: 236913  Cd Length: 148  Bit Score: 125.74  E-value: 1.17e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111691    3 WLPFIAIFL-YVYIEISIFIQVAHVLGVLLTLVLVIFTSVIGMSLVRNQGFKNFVLMQQKMAAGENPAAEMIKSVSLIIA 81
Cdd:PRK11463   1 MRPFLLLFLlYPLIEIAVFIAVASVIGVGWTLLLVILTSVLGVLLARSQGFKTLLRAQRKLARGELPAAELLDGLLLAVA 80
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 90111691   82 GLLLLLPGFFTDFLGLLLLLPPVQKHLTVKLMPHLRFSRMPGGGFSAGTGGGNTFDGEYQRKDDERDR 149
Cdd:PRK11463  81 GVLLLLPGFVTDILGLLLLLPPTRALLRPKLMKRLRRKRNFNGGFSAPGGGGDVIDGEYERKDDPDDR 148
FxsA COG3030
FxsA protein affecting phage T7 exclusion by the F plasmid, UPF0716 family [General function ...
1-145 3.53e-37

FxsA protein affecting phage T7 exclusion by the F plasmid, UPF0716 family [General function prediction only];


Pssm-ID: 442266  Cd Length: 144  Bit Score: 124.50  E-value: 3.53e-37
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111691   1 MRWLPFIAIFLYVYIEISIFIQVAHVLGVLLTLVLVIFTSVIGMSLVRNQGFKNFVLMQQKMAAGENPAAEMIKSVSLII 80
Cdd:COG3030   1 MFRLLLLLFLLLPLLEIALLIQVGSAIGVLPTLLLVVLTAVLGLLLLRRQGLRTLRRLQQALAQGELPARELLDGALLLL 80
                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 90111691  81 AGLLLLLPGFFTDFLGLLLLLPPVQKHLTVKLMPHLRFsRMPGGGFSAGTGGGNTFDGEYQRKDD 145
Cdd:COG3030  81 AGALLLTPGFLTDALGLLLLLPPVRRLLRRLLLRRVVV-RVRSAGTGPRPGDGDVIEGEFEREDD 144
FxsA pfam04186
FxsA cytoplasmic membrane protein; This is a bacterial family of cytoplasmic membrane proteins. ...
7-115 4.07e-21

FxsA cytoplasmic membrane protein; This is a bacterial family of cytoplasmic membrane proteins. It includes two transmembrane regions. The molecular function of FxsA is unknown, but in Escherichia coli its over-expression has been shown to alleviate the exclusion of phage T7 in those cells with an F plasmid.


Pssm-ID: 427769  Cd Length: 109  Bit Score: 82.50  E-value: 4.07e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111691     7 IAIFLYVYIEISIFIQVAHVLGVLLTLVLVIFTSVIGMSLVRNQGFKNFVLMQQKMAAGENPAAEMIKSVSLIIAGLLLL 86
Cdd:pfam04186   1 LLFLLVPLLEIALLILVGSAIGVLPTLLLVILTALLGAALARRQGRRTLRRLQQALAQGRMPGRELLDGLLLLVGGVLLL 80
                          90       100
                  ....*....|....*....|....*....
gi 90111691    87 LPGFFTDFLGLLLLLPPVQKHLTVKLMPH 115
Cdd:pfam04186  81 TPGFVTDVLGLLLLLPPTRRLIRRLLARR 109
 
Name Accession Description Interval E-value
fxsA PRK11463
phage T7 F exclusion suppressor FxsA; Reviewed
3-149 1.17e-37

phage T7 F exclusion suppressor FxsA; Reviewed


Pssm-ID: 236913  Cd Length: 148  Bit Score: 125.74  E-value: 1.17e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111691    3 WLPFIAIFL-YVYIEISIFIQVAHVLGVLLTLVLVIFTSVIGMSLVRNQGFKNFVLMQQKMAAGENPAAEMIKSVSLIIA 81
Cdd:PRK11463   1 MRPFLLLFLlYPLIEIAVFIAVASVIGVGWTLLLVILTSVLGVLLARSQGFKTLLRAQRKLARGELPAAELLDGLLLAVA 80
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 90111691   82 GLLLLLPGFFTDFLGLLLLLPPVQKHLTVKLMPHLRFSRMPGGGFSAGTGGGNTFDGEYQRKDDERDR 149
Cdd:PRK11463  81 GVLLLLPGFVTDILGLLLLLPPTRALLRPKLMKRLRRKRNFNGGFSAPGGGGDVIDGEYERKDDPDDR 148
FxsA COG3030
FxsA protein affecting phage T7 exclusion by the F plasmid, UPF0716 family [General function ...
1-145 3.53e-37

FxsA protein affecting phage T7 exclusion by the F plasmid, UPF0716 family [General function prediction only];


Pssm-ID: 442266  Cd Length: 144  Bit Score: 124.50  E-value: 3.53e-37
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111691   1 MRWLPFIAIFLYVYIEISIFIQVAHVLGVLLTLVLVIFTSVIGMSLVRNQGFKNFVLMQQKMAAGENPAAEMIKSVSLII 80
Cdd:COG3030   1 MFRLLLLLFLLLPLLEIALLIQVGSAIGVLPTLLLVVLTAVLGLLLLRRQGLRTLRRLQQALAQGELPARELLDGALLLL 80
                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 90111691  81 AGLLLLLPGFFTDFLGLLLLLPPVQKHLTVKLMPHLRFsRMPGGGFSAGTGGGNTFDGEYQRKDD 145
Cdd:COG3030  81 AGALLLTPGFLTDALGLLLLLPPVRRLLRRLLLRRVVV-RVRSAGTGPRPGDGDVIEGEFEREDD 144
FxsA pfam04186
FxsA cytoplasmic membrane protein; This is a bacterial family of cytoplasmic membrane proteins. ...
7-115 4.07e-21

FxsA cytoplasmic membrane protein; This is a bacterial family of cytoplasmic membrane proteins. It includes two transmembrane regions. The molecular function of FxsA is unknown, but in Escherichia coli its over-expression has been shown to alleviate the exclusion of phage T7 in those cells with an F plasmid.


Pssm-ID: 427769  Cd Length: 109  Bit Score: 82.50  E-value: 4.07e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 90111691     7 IAIFLYVYIEISIFIQVAHVLGVLLTLVLVIFTSVIGMSLVRNQGFKNFVLMQQKMAAGENPAAEMIKSVSLIIAGLLLL 86
Cdd:pfam04186   1 LLFLLVPLLEIALLILVGSAIGVLPTLLLVILTALLGAALARRQGRRTLRRLQQALAQGRMPGRELLDGLLLLVGGVLLL 80
                          90       100
                  ....*....|....*....|....*....
gi 90111691    87 LPGFFTDFLGLLLLLPPVQKHLTVKLMPH 115
Cdd:pfam04186  81 TPGFVTDVLGLLLLLPPTRRLIRRLLARR 109
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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